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Your search keyword '"Parab, Rakshita"' showing total 8 results
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8 results on '"Parab, Rakshita"'

1. Take-home naloxone administered in emergency settings: feasibility of intervention implementation in a cluster randomized trial

Author

Snooks, Helen A., Jones, Jenna K., Bell, Fiona B., Benger, Jonathon R., Black, Sarah L., Dixon, Simon, Edwards, Adrian, Emery, Helena, Evans, Bridie A., Fuller, Gordon W., Goodacre, Steve, Hoskins, Rebecca, Hughes, Jane, John, Ann, Johnston, Sasha, Jones, Matthew B., Moore, Chris R., Parab, Rakshita, Pilbery, Richard, Sampson, Fiona C., and Watkins, Alan

Published
2024
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2. Is a definitive trial of Take-Home Naloxone in emergency settings indicated? Results of a cluster randomised feasibility study

Author

Snooks, Helen A, primary, Jones, Jenna K, additional, Bell, Fiona B, additional, Benger, Jonathon R, additional, Black, Sarah L, additional, Dixon, Simon, additional, Edwards, Adrian, additional, Emery, Helena, additional, Evans, Bridie A, additional, Fuller, Gordon W, additional, Goodacre, Steve, additional, Hoskins, Rebecca, additional, John, Ann, additional, MClinRes, Sasha Johnston, additional, Jones, Matthew B, additional, Moore, Chris R, additional, Parab, Rakshita, additional, Pilbery, Richard, additional, Sampson, Fiona C, additional, and Watkins, Alan, additional

Published
2024
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5. Evaluating the impact of minimum unit pricing for alcohol on road traffic accidents in Scotland after 20 months: An interrupted time series study.

Author

Manca, Francesco, Parab, Rakshita, Mackay, Daniel, Fitzgerald, Niamh, and Lewsey, Jim

Subjects
*ALCOHOLISM, *TRAFFIC accidents, *CONFIDENCE intervals, *SOCIOECONOMIC factors, *TIME series analysis, *HEALTH equity
Abstract

Background and aims: On 1 May 2018, Scotland implemented Minimum Unit Pricing (MUP) of £0.50 per unit of alcohol with the aim to lower alcohol consumption and related harms, and reduce health inequalities. We measured the impact of MUP on the most likely categories of road traffic accidents (RTAs) to be affected by drink‐driving episodes (fatal and nighttime) up to 20 months after the policy implementation. Further, we checked whether any association varied by level of socio‐economic deprivation. Methods: An interrupted time series design was used to evaluate the impact of MUP on fatal and nighttime RTAs in Scotland and any effect modification across socio‐economic deprivation groups. RTAs in England and Wales (E&W) were used as a comparator. Covariates representing severe weather events, bank holidays, seasonal and underlying trends were adjusted for. Results: In Scotland, MUP implementation was associated with 40.5% (95% confidence interval: 15.5%, 65.4%) and 11.4% (−1.1%, 24.0%) increases in fatal and nighttime RTAs, respectively. There was no evidence of differential impacts of MUP by level of socio‐economic deprivation. While we found a substantial increase in fatal RTAs associated with MUP, null effects observed in nighttime RTAs and high uncertainty in sensitivity analyses suggest caution be applied before attributing causation to this association. Conclusion: There is no evidence of an association between the introduction of minimum unit pricing for alcohol in Scotland and a reduction in fatal and nighttime road traffic accidents, these being outcome measure categories that are proxies of outcomes that directly relate alcohol consumption to road traffic accidents. [ABSTRACT FROM AUTHOR]

Published
2024
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8. PP68 The epidemiology of opioid overdose related decedents: extended evidence from routine data

Author

Parab, Rakshita, Snooks, Helen, Emery, Helena, and Watkins, Alan

Abstract

BackgroundThe incidence of fatal opioid overdoses is a growing and significant health concern in developed countries. We aimed to describe demographic attributes and healthcare utilisation of individuals who died due to opioid overdose in Wales using routine data. This research is a part of the TIME study on the feasibility of using Take-Home Naloxone kits to reduce deaths related to opioid overdose.MethodsA retrospective cross-sectional analysis was conducted for data from January 1st2015 to November 30th2021. Anonymised individual-level records from six Welsh routine data sources: Annual District Death Extract (ADDE); the Emergency Department Data Set (EDDS); the Patient Episode Database for Wales (PEDW); the Critical Care Data Set (CCDS); Substance misuse Dataset (SMDS) and the Welsh Longitudinal General Practice (WLGP) were linked within the SAIL databank. Residents in Wales aged 18 or above within the study window were assessed, censoring at final date of residency in Wales. Deaths were classified as related to opioid overdose (or not) using ICD-10 coding framework, and healthcare events identified within 12 months of study end dates. Composite measures of healthcare utilisation due to opioid overdose (or otherwise) were derived.ResultsDemographic characteristics:1,105 deaths related to opioid overdose. Predominantly male (n=785, 71%), middle-aged (25% opioid overdoses aged 46-55; mean age: 44.3 years) and resident in the most deprived areas (40%). 50% of deaths were classified as accidental; heroin was explicitly noted in 60% of cases. Healthcare utilisation events 1 year prior to deaths:Opioid overdose related: 144 (13%) cases in EDDS, 56 (5%) cases in PEDW and 165 (15%) cases in SMDS. All other events: 682 (62%) cases in EDDS; 483 (44%) cases in PEDW; 118 (11%) cases in CCDS; 243 (22%) cases in SMDS. No healthcare event recorded:Over a quarter of cases (n=307, 28%) had no recorded healthcare event, whether related to opioid overdose or other events.ConclusionPeople who died with an opioid related cause were predominantly male, middle-aged, and more likely to live in relatively deprived areas. Healthcare utilisation for opioid-related causes in 12 months prior to death was generally low. 28% of decedents had no recorded contact at all with acute care providers.

Published
2023
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