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365 results on '"Pappagianis D"'

7. Systemic Mycosis

Author

Solano Aquilar, E., Negroni, R., Meinhof, W., Padilha-Gonçalves, A., Pappagianis, D., Iwata, K., González Mendoza, A., Graybill, J. R., Orfanos, Constantin E., editor, Stadler, Rudolf, editor, and Gollnick, Harald, editor

Published
1988
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28. Cerebrospinal fluid antibodies detected by ELISA against a 33-kDa antigen from spherules of Coccidioides immitis in patients with coccidioidal meningitis. The National Institute of Allergy and Infectious Diseases Mycoses Study Group.

Author

Galgiani JN, Peng T, Lewis ML, Cloud GA, Pappagianis D, Galgiani, J N, Peng, T, Lewis, M L, Cloud, G A, and Pappagianis, D

Abstract

Antibodies against a 33-kDa antigen from Coccidioides immitis were detected by ELISA in patients' cerebrospinal fluid (CSF). Anti-33-kDa antibodies were detected at dilutions > 1:80 in only 1 (1.4%) of 73 patients without coccidioidal meningitis but in 74 (71.8%) of 103 with meningitis. Anti-33-kDa antibodies were detected in 53 (91.4%) of 58 patients whose anti-coccidioidal complement-fixing (CF) antibodies were detectable and in 21 (46.7%) of 45 patients whose CSF was negative by CF test (positive predictive value, 99%; negative predictive value, 71%; sensitivity, 72%; specificity, 99%). Anti-33-kDa antibodies, among which IgG1 was the dominant subclass, increased when infections worsened and decreased when patients' conditions improved. Antibody concentration appeared to be independent of most baseline findings, although only 1 of 5 patients coinfected with human immunodeficiency virus had initially detectable antibodies. Measurement of anti-33-kDa antibodies is a sensitive indicator of coccidioidal meningitis and of its clinical course. [ABSTRACT FROM AUTHOR]

Published
1996

49. Clinical perspectives. Mammary candidosis in lactating women.

Author

Heinig MJ, Francis J, and Pappagianis D

Abstract

Though perceived to be a growing problem by lactation professionals, fungal infection of the breast (mammary candidosis) is largely unstudied. Candida albicans, a commensal organism encountered frequently in the vagina and gastrointestinal tract of humans, has been reported to be responsible for both superficial (cutaneous) and localized (ductal) infection of the mammary gland in lactating women, though the latter association is not universally accepted. Severe pain is considered to be characteristic of yeast infection of the breast and may be a cause of premature weaning among lactating mothers. Given that pain is often the complaint that prompts mothers to consult lactation professionals, it is important that healthcare providers working with lactating women be knowledgeable about this disease. In this article, current research regarding yeast infection of the breast is summarized, including morphology and pathology, diagnosis, risk factors, and common treatment options. [ABSTRACT FROM AUTHOR]

Published
1999
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