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7 results on '"Papatzikas, Grigorios"'

1. Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells

Author

Vilaplana-Lopera, Nuria, primary, Cuminetti, Vincent, additional, Almaghrabi, Ruba, additional, Papatzikas, Grigorios, additional, Rout, Ashok Kumar, additional, Jeeves, Mark, additional, González, Elena, additional, Alyahyawi, Yara, additional, Cunningham, Alan, additional, Erdem, Ayşegül, additional, Schnütgen, Frank, additional, Raghavan, Manoj, additional, Potluri, Sandeep, additional, Cazier, Jean-Baptiste, additional, Schuringa, Jan Jacob, additional, Reed, Michelle AC, additional, Arranz, Lorena, additional, Günther, Ulrich L, additional, and Garcia, Paloma, additional

Published
2022
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2. Author response: Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells

Author

Vilaplana-Lopera, Nuria, primary, Cuminetti, Vincent, additional, Almaghrabi, Ruba, additional, Papatzikas, Grigorios, additional, Rout, Ashok Kumar, additional, Jeeves, Mark, additional, González, Elena, additional, Alyahyawi, Yara, additional, Cunningham, Alan, additional, Erdem, Ayşegül, additional, Schnütgen, Frank, additional, Raghavan, Manoj, additional, Potluri, Sandeep, additional, Cazier, Jean-Baptiste, additional, Schuringa, Jan Jacob, additional, Reed, Michelle AC, additional, Arranz, Lorena, additional, Günther, Ulrich L, additional, and Garcia, Paloma, additional

Published
2022
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4. Association of Vitamin D Receptor Gene Polymorphisms with Serum Vitamin D Levels in a Greek Rural Population (Velestino Study)

Author

Divanoglou, Natalia Komninou, Despina Stea, Eleni A. and Argiriou, Anagnostis Papatzikas, Grigorios Tsakalof, Andreas and Pazaitou-Panayiotou, Kalliopi Georgakis, Marios K. Petridou, Eleni

Abstract

Background/Aim: An alarming increase in vitamin D deficiency even in sunny regions highlights the need for a better understanding of the genetic background of the vitamin D endocrine system and the molecular mechanisms of gene polymorphisms of the vitamin D receptor (VDR). In this study, the serum levels of 25(OH)D-3 were correlated with common VDR polymorphisms (ApaI, BsmI, FokI, and TaqI) in 98 subjects of a Greek homogeneous rural population. Methods: 25(OH)D-3 concentration was measured by ultra-HPLC, and the VDR gene polymorphisms were identified by quantitative real-time PCR followed by amplicon high-resolution melting analysis. Results: Subjects carrying either the B BsmI (OR: 0.52, 95% CI: 0.27-0.99) or t TaqI (OR: 2.06, 95%: 1.06-3.99) allele presented twice the risk for developing vitamin D deficiency compared to the reference allele. Moreover, subjects carrying 1, 2, or all 3 of these genotypes (BB/Bb, Tt/tt, and FF) demonstrated 2-fold (OR: 2.04, 95% CI: 0.42-9.92), 3.6-fold (OR: 3.62, 95% CI: 1.07-12.2), and 7-fold (OR: 6.92, 95% CI: 1.68-28.5) increased risk for low 25(OH)D-3 levels, respectively. Conclusions: Our findings reveal a cumulative effect of specific VDR gene polymorphisms that may regulate vitamin D concentrations explaining, in part, the paradox of vitamin D deficiency in sunny regions, with important implications for precision medicine.

Published
2021

5. Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells

Author

Vilaplana-Lopera, Nuria, primary, Almaghrabi, Ruba, additional, Papatzikas, Grigorios, additional, Cuminetti, Vincent, additional, Jeeves, Mark, additional, González, Elena, additional, Cunningham, Alan, additional, Erdem, Ayşegül, additional, Schnuetgen, Frank, additional, Raghavan, Manoj, additional, Potluri, Sandeep, additional, Cazier, Jean-Baptiste, additional, Schuringa, Jan Jacob, additional, Reed, Michelle AC, additional, Arranz, Lorena, additional, Günther, Ulrich L, additional, and Garcia, Paloma, additional

Published
2021
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7. Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL

Author

Kwok, Marwan, primary, Oldreive, Ceri, additional, Rawstron, Andy C., additional, Goel, Anshita, additional, Papatzikas, Grigorios, additional, Jones, Rhiannon E., additional, Drennan, Samantha, additional, Agathanggelou, Angelo, additional, Sharma-Oates, Archana, additional, Evans, Paul, additional, Smith, Edward, additional, Dalal, Surita, additional, Mao, Jingwen, additional, Hollows, Robert, additional, Gordon, Naheema, additional, Hamada, Mayumi, additional, Davies, Nicholas J., additional, Parry, Helen, additional, Beggs, Andrew D., additional, Munir, Talha, additional, Moreton, Paul, additional, Paneesha, Shankara, additional, Pratt, Guy, additional, Taylor, A. Malcolm R., additional, Forconi, Francesco, additional, Baird, Duncan M., additional, Cazier, Jean-Baptiste, additional, Moss, Paul, additional, Hillmen, Peter, additional, and Stankovic, Tatjana, additional

Published
2020
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