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565 results on '"Papalois, Vassilios"'

2. Evaluation of non-invasive biomarkers of kidney allograft rejection in a prospective multicenter unselected cohort study (EU-TRAIN)

Author

Goutaudier, Valentin, Danger, Richard, Catar, Rusan Ali, Racapé, Maud, Philippe, Aurélie, Elias, Michelle, Raynaud, Marc, Aubert, Olivier, Bouton, Didier, Girardin, François, Vicaut, Éric, Yaiche, Sarhan, Demotes, Jacques, Heidecke, Harald, Taupin, Jean-Luc, Randoux-Lebrun, Christine, Zaidan, Mohamad, Papuchon, Emmanuelle, Le Mai, Hoa, Nguyen, Thi-Van-Ha, Moreso, Francesc, Berney, Thierry, Villard, Jean, Legendre, Christophe, Dragun, Duska, Papalois, Vassilios, Potena, Luciano, Giral, Magali, Gourraud, Pierre-Antoine, Brouard, Sophie, Crespo, Elena, Halleck, Fabian, Budde, Klemens, Bestard, Oriol, Loupy, Alexandre, and Lefaucheur, Carmen

Published
2024
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7. Surgical Back-Table Procedures

Author

Muthusamy, Anand Sivaprakash Rathnasamy, Gopal, Jeevan Prakash, Papalois, Vassilios E., Gruessner, Rainer W. G., editor, and Gruessner, Angelika C., editor

Published
2023
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15. COVID-19 pandemic and worldwide organ transplantation: a population-based study

Author

Aubert, Olivier, Yoo, Daniel, Zielinski, Dina, Cozzi, Emanuele, Cardillo, Massimo, Dürr, Michael, Domínguez-Gil, Beatriz, Coll, Elisabeth, Da Silva, Margarida Ivo, Sallinen, Ville, Lemström, Karl, Midtvedt, Karsten, Ulloa, Camilo, Immer, Franz, Weissenbacher, Annemarie, Vallant, Natalie, Basic-Jukic, Nikolina, Tanabe, Kazunari, Papatheodoridis, Georgios, Menoudakou, Georgia, Torres, Martin, Soratti, Carlos, Hansen Krogh, Daniela, Lefaucheur, Carmen, Ferreira, Gustavo, Silva, Helio Tedesco, Jr, Hartell, David, Forsythe, John, Mumford, Lisa, Reese, Peter P, Kerbaul, François, Jacquelinet, Christian, Vogelaar, Serge, Papalois, Vassilios, and Loupy, Alexandre

Published
2021
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17. Informing the Risk of Kidney Transplantation Versus Remaining on the Waitlist in the Coronavirus Disease 2019 Era

Author

Appelbe, Maura, Brown, Edwina, Cairns, Tom, Clerkin, Caroline, Condon, Marie, Corbett, Richard W., Crane, Jeremy, Dor, Frank, Duncan, Neill, Edwards, Claire, Fernandes da costa, Fabiana, Frankel, Andrew, Goodall, Dawn, Harris, Julie, Harris, Sharon, Herbert, Paul, Hill, Peter, Kousios, Andreas, Levy, Jeremy B., Liu, Lian, Loucaidou, Marina, Lynch, Kathleen, Medjeral-Thomas, Nicholas, Moabi, Dihlabelo, Muthusamy, Anand, Nevin, Margaret, Palmer, Andrew, Parsons, Darren, Prout, Virginia, Punzalan, Sue, Salisbury, Emma, Sandhu, Eleanor, Smith, Colin, Storey, Roland, Tanna, Anisha, Tansey, Katie, Thomas, David, Tomlinson, James, Papalois, Vassilios, Webster, Phil, Yang, Dejing, Clarke, Candice, Lucisano, Gaetano, Prendecki, Maria, Gleeson, Sarah, Martin, Paul, Ali, Mahrukh, McAdoo, Stephen P., Lightstone, Liz, Ashby, Damien, Charif, Rawya, Griffith, Megan, McLean, Adam, and Willicombe, Michelle

Published
2021
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20. Delivery of Mesenchymal Stem Cells during Hypothermic Machine Perfusion in a Translational Kidney Perfusion Study.

Author

Vallant, Natalie, Wolfhagen, Nienke, Sandhu, Bynvant, Hamaoui, Karim, and Papalois, Vassilios

Subjects
MESENCHYMAL stem cells, PERFUSION, REPERFUSION, KIDNEYS, OXYGEN consumption, COLD storage, REPERFUSION injury
Abstract

In transplantation, hypothermic machine perfusion (HMP) has been shown to be superior to static cold storage (SCS) in terms of functional outcomes. Ex vivo machine perfusion offers the possibility to deliver drugs or other active substances, such as Mesenchymal Stem Cells (MSCs), directly into an organ without affecting the recipient. MSCs are multipotent, self-renewing cells with tissue-repair capacities, and their application to ameliorate ischemia- reperfusion injury (IRI) is being investigated in several preclinical and clinical studies. The aim of this study was to introduce MSCs into a translational model of hypothermic machine perfusion and to test the efficiency and feasibility of this method. Methods: three rodent kidneys, six porcine kidneys and three human kidneys underwent HMP with 1–5 × 106 labelled MSCs within respective perfusates. Only porcine kidneys were compared to a control group of 6 kidneys undergoing HMP without MSCs, followed by mimicked reperfusion with whole blood at 37 °C for 2 h for all 12 kidneys. Reperfusion perfusate samples were analyzed for levels of NGAL and IL-β by ELISA. Functional parameters, including urinary output, oxygen consumption and creatinine clearance, were compared and found to be similar between the MSC treatment group and the control group in the porcine model. IL-1β levels were higher in perfusate and urine samples in the MSC group, with a median of 285.3 ng/mL (IQR 224.3–407.8 ng/mL) vs. 209.2 ng/mL (IQR 174.9–220.1), p = 0.51 and 105.3 ng/mL (IQR 71.03–164.7 ng/mL) vs. 307.7 ng/mL (IQR 190.9–349.6 ng/mL), p = 0.16, respectively. MSCs could be traced within the kidneys in all models using widefield microscopy after HMP. The application of Mesenchymal Stem Cells in an ex vivo hypothermic machine perfusion setting is feasible, and MSCs can be delivered into the kidney grafts during HMP. Functional parameters during mimicked reperfusion were not altered in treated kidney grafts. Changes in levels of IL-1β suggest that MSCs might have an effect on the kidney grafts, and whether this leads to a positive or a negative outcome on IRI in transplantation needs to be determined in further experiments. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Contributors

Author

Abrams, Peter, primary, Adler, Joel T., additional, Alejandro, Rodolfo, additional, Alibashe-Ahmed, Mohamed, additional, Alvarez, Ana, additional, Anazawa, Takayuki, additional, Andres, Axel, additional, Antonioli, Barbara, additional, Apete, Alan, additional, Axelrod, David A., additional, Badet, Lionel, additional, Baidal, David, additional, Barrera, Kaylene, additional, Benhamou, Pierre-Yves, additional, Berney, Thierry, additional, Bertoni, Alain Gerald, additional, Bertuzzi, Federico, additional, Boggi, Ugo, additional, Bonner, Caroline, additional, Bozorgzadeh, Adel, additional, Branchereau, Julien, additional, Bromberg, Jonathan, additional, Burke, George W., additional, Buron, Fanny, additional, Caiazzo, Robert, additional, Caldara, Rossana, additional, Camhi, Stephanie S., additional, Cantarovich, Diego, additional, Cardillo, Massimo, additional, Castanares-Zapatero, D., additional, Cattan, Pierre, additional, Chandran, Suresh Rama, additional, Chang, Erin, additional, Chen, Linda, additional, Chetboun, Mikael, additional, Choudhary, Pratik, additional, Ciancio, Gaetano, additional, Cicalese, Maria Pia, additional, Citro, Antonio, additional, Collienne, C., additional, Conte, Caterina, additional, Counter, Claire, additional, Dajani, Khaled Z., additional, Darden, Carly M., additional, De Cobelli, Francesco, additional, de Koning, Eelco J.P., additional, De Leon, Hector, additional, Delalleau, Nathalie, additional, DiChiacchio, Laura, additional, Doppenberg, Jason B., additional, Drachenberg, Cinthia B., additional, Dugnani, Erica, additional, Dunn, Ty B., additional, Engelse, Marten A., additional, Farag, Ahmed, additional, Farney, Alan, additional, Farrow, Anne Elizabeth, additional, Fathi, Ibrahim, additional, Figueiro, Jose, additional, Flatt, Anneliese, additional, Fousteri, Georgia, additional, Fridell, Jonathan A., additional, Friend, Peter J., additional, Gastaldi, Giacomo, additional, Gmyr, Valery, additional, Gonzalez, Javier, additional, Gopal, Jeevan Prakash, additional, Gorus, Frans K., additional, Goto, Masafumi, additional, Gotoh, Mitsukazu, additional, Greget, Michel, additional, Grenet, Dominique, additional, Grossi, Paolo Antonio, additional, Gruessner, Rainer W.G., additional, Gruessner, Angelika C., additional, Harriman, David I., additional, Hawthorne, Wayne J., additional, Hellman, Jarl, additional, Holbert, Brenda Lee, additional, Hubert, Thomas, additional, Iacopi, Sara, additional, Infante, Marco, additional, Jacob, Peter, additional, Johnson, Paul, additional, Kandaswamy, Raja, additional, Karam, Georges, additional, Kaufman, Dixon B., additional, Kendall Jr, W.F., additional, Kensinger, Clark D., additional, Kenyon, Norma S., additional, Kerr-Conte, Julie, additional, Kervella, Delphine, additional, Kessler, Laurence, additional, Kessler, Romain, additional, Keymeulen, Bart, additional, Korsgren, Olle, additional, Lablanche, Sandrine, additional, Lakhani, Muhaib, additional, Lalwani, Neeraj, additional, Laterre, P.F., additional, Lawrence, Michael C., additional, Lee, Frances Tangherlini, additional, Lehmann, Roger, additional, Linetsky, Elina, additional, Ludwig, Barbara, additional, Lundgren, Torbjörn, additional, Luo, Xunrong, additional, Madiraju, SriGita, additional, Maffi, Paola, additional, Magistretti, Paola, additional, Mapihan, Kristell Le, additional, Markmann, James F., additional, Martens, Geert, additional, Martins, Paulo N., additional, Mazzotta, Francesco Antonio, additional, Mekala, Kavya Chitra, additional, Melzi, Raffaella, additional, Mercalli, Alessia, additional, Monti, Paolo, additional, Morsi, Mahmoud, additional, Mosca, Irene, additional, Mourad, M., additional, Muthusamy, Anand S. Rathnasamy, additional, Nano, Rita, additional, Naziruddin, Bashoo, additional, Noel, Christian, additional, O’Callaghan, John, additional, Odorico, Jon S., additional, Olland, Anne, additional, Opara, E.C., additional, Orlando, Giuseppe, additional, Padilla, Nathalia, additional, Papadimitriou, John C., additional, Papalois, Vassilios E., additional, Papas, Klearchos K., additional, Pasquetti, Gianni, additional, Pattou, François, additional, Pellegrini, Silvia, additional, Pernin, Nadine, additional, Perrone, Vittorio Grazio, additional, Piemonti, Lorenzo, additional, Ploeg, Rutger, additional, Powelson, John A., additional, Pugliese, Alberto, additional, Rajan, Shanthini K., additional, Ramanathan, Karthik V., additional, Raverdy, Violeta, additional, Redfield, Robert R., additional, Renz, John, additional, Rickels, Michael R., additional, Rickert, Charles G., additional, Ricordi, Camillo, additional, Rogers, Jeffrey, additional, Scalea, Joseph R., additional, Schold, Jesse D., additional, Scholz, Hanne, additional, Secchi, Antonio, additional, Serrano, Oscar K., additional, Shapiro, A.M. James, additional, Sharma, Sidharth, additional, Sharples, Edward, additional, Shaw, James A.M., additional, Sinha, Sanjay, additional, Socci, Carlo, additional, Squifflet, Jean-Paul G., additional, Stock, Peter G., additional, Stratta, Robert J., additional, Sutherland, David E.R., additional, Tesauro, Manfredi, additional, Thaunat, Olivier, additional, Thévenet, Julien, additional, Troppmann, Christoph, additional, Vantyghem, Marie-Christine, additional, Vendrame, Francesco, additional, Venturini, Massimo, additional, Vianna, Rodrigo, additional, Vistoli, Fabio, additional, von Zur-Mühlen, Bengt, additional, Wittebole, X., additional, Wojtusciszyn, Anne, additional, Zarinsefat, Arya, additional, and Zimmerman, Asha, additional

Published
2020
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26. European Society for Organ Transplantation (ESOT) Consensus Statement on the Role of Pancreas Machine Perfusion to Increase the Donor Pool for Beta Cell Replacement Therapy

Author

Ferrer-Fàbrega, Joana, primary, Mesnard, Benoît, additional, Messner, Franka, additional, Doppenberg, Jason B., additional, Drachenberg, Cinthia, additional, Engelse, Marten A., additional, Johnson, Paul R. V., additional, Leuvenink, Henri G. D., additional, Oniscu, Gabriel C., additional, Papalois, Vassilios, additional, Ploeg, Rutger J., additional, Reichman, Trevor W., additional, Scott, William E, additional, Vistoli, Fabio, additional, Berney, Thierry, additional, Jacobs-Tulleneers-Thevissen, Daniel, additional, Kessaris, Nicos, additional, Weissenbacher, Annemarie, additional, Ogbemudia, Ann Etohan, additional, White, Steve, additional, and Branchereau, Julien, additional

Published
2023
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27. The Medical Community’s Role in Communication Strategies during Health Crises—Perspective from European Union of Medical Specialists (UEMS)

Author

Nadareishvili, Ilia, primary, Bazas, Theodore, additional, Petrosillo, Nicola, additional, Berce, Vojko, additional, Firth, John, additional, Mansilha, Armando, additional, Leventer, Mihaela, additional, Renieri, Alessandra, additional, Zampolini, Mauro, additional, and Papalois, Vassilios, additional

Published
2023
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31. Evaluating the educational environment of an international animal model-based wet lab course for undergraduate students

Author

Sideris, Michail Ch., Papalois, Apostolos E., Athanasiou, Thanos, Dimitropoulos, Ioannis, Theodoraki, Korina, Dos Santos, Francois Sousa, Paparoidamis, Georgios, Staikoglou, Nikolaos, Pissas, Dimitrios, Whitfield, Peter C., Rampotas, Alexandros, Papagrigoriadis, Savvas, Papalois, Vassilios, Zografos, Georgios, and Tsoulfas, Georgios

Published
2016
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32. Introducing In Vivo Dissection Modules for Undergraduate Level Trainees: What Is the Actual Benefit and How Could We Make It More Efficient?

Author

Sideris, Michail, Papalois, Apostolos, Theodoraki, Korina, Paparoidamis, Georgios, Staikoglou, Nikolaos, Tsagkaraki, Ismini, Koletsis, Efstratios, Dedeilias, Panagiotis, Lymperopoulos, Nikolaos, Imprialos, Konstantinos, Papagrigoriadis, Savvas, Papalois, Vassilios, Zografos, Georgios, and Tsoulfas, Georgios

Published
2018
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41. Health Literacy

Author

Theodosopoulou, Maria, primary, Dor, Frank J. M. F., additional, Casanova, Daniel, additional, Baskozos, Georgios, additional, and Papalois, Vassilios, additional

Published
2018
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49. The Impact of Cold Ischaemia Time on Outcomes of Living Donor Kidney Transplantation:A Systematic Review and Meta-Analysis

Author

van de Laar, Stijn C, Lafranca, Jeffrey A, Minnee, Robert C, Papalois, Vassilios, Dor, Frank J M F, van de Laar, Stijn C, Lafranca, Jeffrey A, Minnee, Robert C, Papalois, Vassilios, and Dor, Frank J M F

Abstract

Studies have been carried out to investigate the effect of a prolonged cold ischaemia time (CIT) on the outcomes of living donor kidney transplantation (LDKT). There is no clear consensus in the literature about the effects of CIT on LDKT outcomes, and therefore, we performed a systematic review and meta-analysis to provide evidence on this subject. Searches were performed in five databases up to 12 July 2021. Articles comparing different CIT in LDKT describing delayed graft function (DGF), graft and patient survival, and acute rejection were considered for inclusion. This study is registered with PROSPERO, CRD42019131438. In total, 1452 articles were found, of which eight were finally eligible, including a total of 164,179 patients. Meta-analyses showed significantly lower incidence of DGF (odds ratio (OR) = 0.61, p < 0.01), and significantly higher 1-year graft survival (OR = 0.72, p < 0.001) and 5-year graft survival (OR = 0.88, p = 0.04), for CIT of less than 4 h. Our results underline the need to keep CIT as short as possible in LDKT (ideally < 4 h), as a shorter CIT in LDKT is associated with a statistically significant lower incidence of DGF and higher graft survival compared to a prolonged CIT. However, clinical impact seems limited, and therefore, in LDKT programmes in which the CIT might be prolonged, such as kidney exchange programmes, the benefits outweigh the risks. To minimize these risks, it is worth considering including CIT in kidney allocation algorithms and in general take precautions to protect high risk donor/recipient combinations.

Published
2022

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