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1. Using an Educational Intervention to Map our Surgical Teams’ Function, Emotional Intelligence, Communication and Conflict Styles

Author: White, Bobbie Ann Adair, Fleshman, James W., Picchioni, Anthony, Hammonds, Kendall P., Gentry, Lonnie, Bird, Erin T., Arroliga, Alejandro C., and Papaconstantinou, Harry T.
Published: 2023
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2. Postoperative Opioid Prescription Reduction Strategy in a Regional Healthcare System

Author: Frazee, Richard, Garmon, Emily, Isbell, Claire, Bird, Erin, and Papaconstantinou, Harry
Published: 2020
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3. Preoperative Frailty Scores Predict the Early Postoperative Complications of Holmium Laser Enucleation of Prostate

Author: Elsaqa, Mohamed, primary, Papaconstantinou, Harry, additional, and El Tayeb, Marawan M., additional
Published: 2023
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4. Room Setup, Equipment, and Patient Positioning

Author: Sharp, Nicole E., Papaconstantinou, Harry T., Geisler, Daniel P., editor, Keller, Deborah S., editor, and Haas, Eric M., editor
Published: 2018
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5. Preoperative Frailty and Surgical Outcomes Across Diverse Surgical Subspecialties in a Large Health Care System

Author: Mrdutt, Mary M., Papaconstantinou, Harry T., Robinson, Bobby D., Bird, Erin T., and Isbell, Claire L.
Published: 2019
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6. Operative Time Accuracy in the Era of Electronic Health Records: Addressing the Elephant in the Room.

Author: Elsaqa, Mohamed, Tayeb, Marawan M. El, and Papaconstantinou, Harry T.
Published: 2024
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7. Checklists in Surgery

Author: Sparks, Eric A., Papaconstantinou, Harry T., Ferguson, Mark K, Series editor, Hyman, Neil, editor, and Umanskiy, Konstantin, editor
Published: 2017
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8. Open vs Closed Negative Pressure Wound Therapy for Contaminated and Dirty Surgical Wounds: A Prospective Randomized Comparison

Author: Frazee, Richard, Manning, Anthony, Abernathy, Stephen, Isbell, Claire, Isbell, Travis, Kurek, Stanley, Regner, Justin, Smith, Randall, and Papaconstantinou, Harry
Published: 2018
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9. NSQIP-Based Quality Improvement Curriculum for Surgical Residents

Author: Mrdutt, Mary M., Isbell, Claire L., Regner, Justin L., Hodges, Bonnie R., Munoz-Maldonado, Yolanda, Thomas, J. Scott, and Papaconstantinou, Harry T.
Published: 2017
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10. Development and Validation of a Methodology to Reduce Mortality Using the Veterans Affairs Surgical Quality Improvement Program Risk Calculator

Author: Keller, Deborah S., Kroll, Donald, Papaconstantinou, Harry T., and Ellis, C. Neal
Published: 2017
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11. Fissure-in-Ano

Author: Essani, Rahila, primary and Papaconstantinou, Harry T., additional
Published: 2019
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12. Contributors

Author: Abbas, Abbas E., primary, Adams, David B., additional, Aggarwal, Piyush, additional, Ahmed, Bestoun H., additional, Albanese, Craig, additional, Albert, Matthew R., additional, Ali, Abubaker, additional, Alicuben, Evan, additional, Allaix, Marco E., additional, Altman, Ashley, additional, Ando, Hisami, additional, Andolfi, Ciro, additional, Annamalai, Alagappan, additional, Asare, Elliot A., additional, Asti, Emanuele, additional, Auchincloss, Hugh G., additional, Babic, Benjamin, additional, Baker, Talia B., additional, Ball, Chad G., additional, Barbetta, Arianna, additional, Barlow, John M., additional, Barr, Justin, additional, Barreto, Juan Camilo, additional, Barry, Linda, additional, Beal, Eliza W., additional, Beard, Kristin Wilson, additional, Beck, David E., additional, Behrns, Kevin E., additional, Bellevue, Oliver C., additional, Bellorin-Marin, Omar E., additional, Bergman, Jacques, additional, Berry, James, additional, Besselink, Marc G.H., additional, Bharucha, Adil E., additional, Bilchik, Anton J., additional, Bildzukewicz, Nikolai A., additional, Bingham, Jason, additional, Birnbaum, Elisa, additional, Black, Sylvester M., additional, Blackmon, Shanda H., additional, Bleier, Joshua I.S., additional, Bodzin, Adam S., additional, Boland, C. Richard, additional, Bolton, John, additional, Bolton, Nathan, additional, Bonavina, Luigi, additional, Bonds, Morgan, additional, Bouwense, Stefan A.W., additional, Boys, Joshua A., additional, Bravo-Infante, Raquel, additional, Bremner, Ross M., additional, Brenner, Bruce M., additional, Brown, Shaun R., additional, Callery, Mark P., additional, Cameron, John L., additional, Camilleri, Michael, additional, Campbell, Jacob, additional, Cassim, Riaz, additional, Castillo-Angeles, Manuel, additional, Cauley, Christy, additional, Cavaness, Keith M., additional, Cerfolio, Robert J., additional, Champagne, Bradley J., additional, Chandrasoma, Parakrama, additional, Chang, Alex L., additional, Chapman, Christopher G., additional, Chapman, William C., additional, Cheek, Susannah, additional, Chen, Harvey S., additional, Cho, Clifford S., additional, Choi, Eric T., additional, Choi, Eugene A., additional, Chojnacki, Karen A., additional, Choti, Michael A., additional, Christie, Ian, additional, Chua, Heidi, additional, Church, James M., additional, Cioffi, Jessica L., additional, Clark, Susannah, additional, Clavien, Pierre-Alain, additional, Cloud, Adam, additional, Colavita, Paul D., additional, Colquhoun, Steven D., additional, Conway, William, additional, Cools-Lartigue, Jonathan, additional, Coosemans, Willy, additional, Cornwell, Edward E., additional, Costantini, Mario, additional, Coyle, Yvonne, additional, Craig, Daniel A., additional, Croome, Kristopher P., additional, Cullen, Joseph J., additional, D'Andrea, Anthony P., additional, Dassopoulos, Themistocles, additional, Davila, Marta L., additional, Davila, Raquel E., additional, DeMeester, Steven R., additional, DeMeester, Tom R., additional, Dempsey, Daniel T., additional, dePrisco, Gregory, additional, Depypere, Lieven, additional, Dietz, David W., additional, Dillhoff, Mary E., additional, DiNorcia, Joseph, additional, Doane, Stephen M., additional, Dogeas, Epameinondas, additional, Dozois, Eric J., additional, Dumon, Kristoffel, additional, Dunn, Stephen P., additional, Dunst, Christy M., additional, Dussel, John N., additional, Dyer, Matthew, additional, Efron, Jonathan, additional, El-Gohary, Yousef, additional, Lakis, Mustapha El, additional, Ellison, E. Christopher, additional, Ellsmere, James, additional, Essani, Rahila, additional, Evans, Douglas B., additional, Fang, Sandy H., additional, Fasen, Geoffrey, additional, Fernando, Hiran C., additional, Ferri, Lorenzo, additional, Fichera, Alessandro, additional, Finck, Christine, additional, Fisher, Oliver M., additional, Fleshman, James W., additional, Fong, Yuman, additional, Foreman, Michael L., additional, Francone, Todd D., additional, Franko, Edward R., additional, French, Daniel, additional, Fuchs, Hans Friedrich, additional, Fuchs, Karl Hermann, additional, Funaki, Brian, additional, Funk, Geoffrey A., additional, Fusco, Joseph, additional, Gaitonde, Shrawan G., additional, Gajjar, Aakash H., additional, Garcia-Aguilar, Julio, additional, Gearhart, Susan, additional, Geller, David A., additional, Ghobadi, Comeron, additional, Gilbert, Sebastien, additional, Giles, David, additional, Gillaspie, Erin, additional, Girotti, Micah, additional, Gittes, George K., additional, Goodman, Michael D., additional, Gooszen, Hein G., additional, Gores, Gregory J., additional, Griffin, James F., additional, Griffin, S. Michael, additional, Grimm, Leander, additional, Grochola, L.F., additional, Habib, Fahim, additional, Hanks, John B., additional, Harris, James E., additional, Hartwig, Matthew G., additional, Hassan, Imran, additional, Hedrick, Traci L., additional, Hicks, Terry C., additional, Hodin, Richard, additional, Hofstetter, Wayne L., additional, Hogg, Melissa, additional, Hu, Yue-Yung, additional, Hungness, Eric S., additional, Hunt, Steven R., additional, Huseynova, Khumara, additional, Hyman, Neil H., additional, Iannitti, David A., additional, Indes, Jeffrey, additional, Jenkins, Megan, additional, Jensen, Todd, additional, Jeziorczak, Paul M., additional, Jilani, Danial, additional, Jiménez-Toscano, Marta, additional, Jobe, Blair A., additional, Johnston, Lily E., additional, Kahrilas, Peter J., additional, Kalady, Matthew F., additional, Kassira, Noor, additional, Katkhouda, Namir, additional, Katz, Philip O., additional, Keller, Deborah S., additional, Kelley, Matthew P., additional, Kennedy, Gregory D., additional, Kent, Tara Sotsky, additional, Kia, Leila, additional, Kibbe, Melina R., additional, Kim, John, additional, King, Alice, additional, Kiran, Ravi P., additional, Kirton, Orlando C., additional, Klein, Andrew, additional, Klein, Eric N., additional, Kohn, Geoffrey P., additional, Kovell, Robert Caleb, additional, Kozol, Robert, additional, Lacy, Antonio M., additional, Ladner, Daniela P., additional, Lagarde, S.M., additional, Laituri, Carrie A., additional, Landmann, Alessandra, additional, Lee, Janet T., additional, Lee, Lawrence L., additional, Leinicke, Jennifer A., additional, Lerut, Toni, additional, Levi, David M., additional, Li, Chao, additional, Liang, Yu, additional, Lichliter, Andrew H., additional, Lichliter, Warren E., additional, Lightner, Amy L., additional, Lile, Deacon J., additional, Lillemoe, Keith D., additional, Lin, Jules, additional, Lin, Shu S., additional, Lipham, John C., additional, Litle, Virginia R., additional, Lodhia, Nayna A., additional, Longo, Walter E., additional, Lord, Reginald V.N., additional, Louie, Brian E., additional, Low, Donald E., additional, Lowe, Val J., additional, Luc, Jessica G.Y., additional, Luketich, James D., additional, Ma, Yanling, additional, MacCarty, Robert L., additional, MacDonald, Blair, additional, Madoff, Robert D., additional, Magge, Deepa, additional, Maheshwari, Anurag, additional, Mahmoud, Najjia N., additional, Mahvi, David A., additional, Mahvi, David M., additional, Mak, Grace Z., additional, Mansfield, Sara A., additional, Manzano, Maricarmen, additional, Maron, David J., additional, Mathew, Melvy S., additional, Mathis, Kellie L., additional, Matthews, Jeffrey B., additional, McFadden, David W., additional, Merchea, Amit, additional, Messaris, Evangelos, additional, Miller, Daniel L., additional, Miller, Heidi J., additional, Millis, J. Michael, additional, Mittal, Sumeet K., additional, Molena, Daniela, additional, Montgomery, Stephanie C., additional, Moore, Ryan, additional, Morgan, Katherine A., additional, Mortenson, Melinda M., additional, Mulholland, Michael W., additional, Mulvihill, Michael S., additional, Mutch, Matthew, additional, Nafteux, Philippe Robert, additional, Nagaraju, Arun, additional, Nagorney, David M., additional, Nathan, Hari, additional, Natoli, Karen R., additional, Navuluri, Rakesh, additional, Nissen, Nicholas N., additional, Nobel, Tamar B., additional, Noordman, B.J., additional, Norton, Jeffrey A., additional, Novitsky, Yuri W., additional, Nussbaum, Michael S., additional, Nyberg, Scott L., additional, Oelschlager, Brant K., additional, Oh, Daniel S., additional, Otero-Piñeiro, Ana, additional, Oto, Aytekin, additional, Pachter, H. Leon, additional, Paidas, Charles N., additional, Palazzo, Francesco, additional, Paniccia, Alessandro, additional, Papaconstantinou, Harry T., additional, Pappas, Theodore N., additional, Pappou, Emmanouil P., additional, Parikh, Manish, additional, Paruch, Jennifer L., additional, Patel, Asish D., additional, Patel, Mikin, additional, Patti, Marco G., additional, Paulson, Emily Carter, additional, Pawlik, Timothy M., additional, Payne, Isaac, additional, Pemberton, John H., additional, Pendola, Michael, additional, Perez, Alexander, additional, Pernar, Luise I.M., additional, Peters, Walter R., additional, Petrowsky, Henrik, additional, Peyre, Christian G., additional, Phillips, Alexander W., additional, Pillai, Lashmikumar, additional, Plummer, Joseph M., additional, Pointer, David T., additional, Poruk, Katherine E., additional, Posner, Mitchell C., additional, Postier, Russell, additional, Prachand, Vivek N., additional, Pritts, Timothy A., additional, Quatrino, Gregory, additional, Ranka, Sagar, additional, Rattner, David W., additional, Reavis, Kevin M., additional, Reddy, Vikram B., additional, Remzi, Feza H., additional, Ricciardi, Rocco, additional, Rice, Thomas W., additional, Richman, Aaron, additional, Rider, Paul, additional, Roberts, John Paul, additional, Roberts, Patricia L., additional, Roggin, Kevin K., additional, Roll, Garrett Richard, additional, Rona, Kais, additional, Rosen, Charles B., additional, Ross, Samuel Wade, additional, Roth, J. Scott, additional, Rushing, Amy P., additional, Safar, Bashar, additional, Saldinger, Pierre F., additional, Samakar, Kamran, additional, Sandhu, Kulmeet K., additional, Schaheen, Lara W., additional, Schirmer, Bruce, additional, Schneider, Andrew, additional, Schulick, Richard D., additional, Schwab, Ben, additional, Scurci, Stephanie, additional, Senagore, Anthony, additional, Shah, Adil A., additional, Shah, Shimul A., additional, Shames, Brian, additional, Shanmugan, Skandan, additional, Shapiro, David S., additional, Silviera, Matthew, additional, Slakey, Douglas P., additional, Sloan, Joshua, additional, Smallwood, Nathan, additional, Smith, Shane P., additional, Smithers, B. Mark, additional, Smoot, Rory L., additional, Soares, Kevin C., additional, Soffer, Edy, additional, Solomina, Julia, additional, Soper, Nathaniel J., additional, Spechler, Stuart Jon, additional, Sridhar, Praveen, additional, Steele, Scott R., additional, Sternbach, Joel M., additional, Stevenson, Christina E., additional, Strong, Scott A., additional, Sucandy, Iswanto, additional, Sundaram, Magesh, additional, Sundaresan, Sudhir, additional, Swanstrom, Lee L., additional, Sylla, Patricia, additional, Takada, Tadahiro, additional, Talbot, Ethan, additional, Tam, Vernissia, additional, Tamm, Eric P., additional, Tatarian, Talar, additional, Tavakkoli, Ali, additional, Te, Helen S., additional, Teitelbaum, Ezra N., additional, Ternent, Charles A., additional, Thompson, Jon S., additional, Thomson, Iain, additional, Thorson, Alan G., additional, Thorson, Chad M., additional, Totten, Crystal F., additional, Truty, Mark J., additional, Tsai, Susan, additional, Tseng, Jennifer, additional, Tullius, Tom, additional, Tzakis, Andreas G., additional, van Lanschot, J.J.B., additional, van Santvoort, Hjalmar C., additional, Van Veer, Hans, additional, Vega, Jorge A., additional, Velanovich, Vic, additional, Vogler, Sarah A., additional, Wang, Huamin, additional, Ward, Mark A., additional, Warner, Brad W., additional, Warner, Susanne G., additional, Watson, Thomas J., additional, Waxman, Irving, additional, Webster-Lake, Carissa, additional, Wei, Benjamin, additional, Weiser, Martin R., additional, Wells, Dennis, additional, Wells, Katerina, additional, Welton, Mark Lane, additional, Wen, Yuxiang, additional, Wendling, Mark R., additional, Wesson, Hadley K.H., additional, Wexner, Steven D., additional, White, Rebekah R., additional, Whitlow, Charles B., additional, Wijnhoven, B.P.L., additional, Wilkes, Justin, additional, Wilson, Rickesha L., additional, Witkowski, Piotr, additional, Wolfgang, Christopher L., additional, Worrell, Stephanie G., additional, Yang, Jian, additional, Yeo, Charles J., additional, Yeung, Ching, additional, Yung, Evan E., additional, Zafar, Syed Nabeel, additional, Zaninotto, Giovanni, additional, Zeh, Herbert, additional, Zehetner, Joerg, additional, Zenilman, Michael E., additional, Zimmerman, Pamela, additional, and Zuccaro, Gregory, additional
Published: 2019
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13. Pilonidal Disease and Hidradenitis Suppurativa

Author: Papaconstantinou, Harry T., Read, Thomas E., Beck, David E., editor, Wexner, Steven D., editor, Hull, Tracy L., editor, Roberts, Patricia L., editor, Saclarides, Theodore J., editor, Senagore, Anthony J., editor, Stamos, Michael J., editor, and Steele, Scott R., editor
Published: 2014
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14. Incidence and predictors of urinary incontinence rates post‐holmium laser enucleation of prostate.

Author: Elsaqa, Mohamed, Zhang, Yu, Papaconstantinou, Harry, and Tayeb, Marawan M. El
Subjects: SURGICAL enucleation, LASER lithotripsy, PROSTATE, ENUCLEATION of the eye, URINARY incontinence, BIVARIATE analysis, REGRESSION analysis, MULTIVARIATE analysis
Abstract: Introduction: One of the main adverse outcomes following Holmium laser enucleation of the prostate (HoLEP) is the development of transient de novo urinary incontinence (UI). We aimed to evaluate the correlation of multiple risk factors to UI rates post‐HoLEP. Methods: A review of prospectively maintained 7 year database for HoLEP patients in a single center was performed. UI data at 6 week, 3 month, and 1 year follow‐up intervals were assessed with bivariate and multivariate analysis of multiple potential risk factors. Results: The study included 666 patients with median (IQR) age of 72 (66–78) years old and median (IQR) preoperative prostate volume of 89 (68–126) gm. UI was seen in 287 (43%), 100 (15%) and 26 (5.8%) at 6 week, 3 month, and 1 year follow up occasions respectively. At 6 weeks follow up, UI type was stress, urge and mixed in 121 (18.16%), 118 (17.72) and 48 (7.21%) patients respectively. Using a multivariate regression analysis, obesity and pre‐operative UI were associated with postoperative UI rate at both 6 week (p =.0065,.031) and 3 month (p =.0261,.044) follow up encounters respectively. Also, larger specimen weight was another predictor for 6 week UI (p =.0399) while higher frailty score was a predictor for UI at 3 month occasion (p =.041). Conclusion: Patients with preoperative UI, obesity, frailty, and large prostate volume are at higher risk of short‐term UI post‐HoLEP up to 3 months. Patients with one or more of these risk factors should be counseled regarding the higher risk of UI. [ABSTRACT FROM AUTHOR]
Published: 2023
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15. Room Setup, Equipment, and Patient Positioning

Author: Sharp, Nicole E., primary and Papaconstantinou, Harry T., additional
Published: 2017
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16. Concurrent Chart Review Provides More Accurate Documentation and Increased Calculated Case Mix Index, Severity of Illness, and Risk of Mortality

Author: Frazee, Richard C., Matejicka, Anthony V., II, Abernathy, Stephen W., Davis, Matthew, Isbell, Travis S., Regner, Justin L., Smith, Randall W., Jupiter, Daniel C., and Papaconstantinou, Harry T.
Published: 2015
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17. Moving beyond teamwork in the operating room to facilitating mutual professional respect

Author: Lin, Melody W., primary, Papaconstantinou, Harry T., additional, and White, Bobbie Ann Adair, additional
Published: 2022
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18. Perspectives on Psychological Safety in the Operating Room: Investigating the Factors That Influence the Culture of Safety in the Operating Room

Author: Lin, Melody W, primary, Papaconstantinou, Harry T, additional, and White, BobbieAnn A, additional
Published: 2022
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19. Pilonidal Disease and Hidradenitis Suppurativa

Author: Papaconstantinou, Harry T., Thomas, J. Scott, Beck, David E., editor, Roberts, Patricia L., editor, Saclarides, Theodore J., editor, Senagore, Anthony J., editor, Stamos, Michael J., editor, and Wexner, Steven D., editor
Published: 2011
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20. Recurrent Rectal Prolapse

Author: Papaconstantinou, Harry T., Billingham, Richard P., editor, Kobashi, Kathleen C., editor, and Peters, William A., editor
Published: 2009
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21. Checklists in Surgery

Author: Sparks, Eric A., primary and Papaconstantinou, Harry T., additional
Published: 2017
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22. Rectal Prolapse in the Elderly: Trends in Surgical Management and Outcomes from the American College of Surgeons National Surgical Quality Improvement Program Database

Author: Clark, Clarence E., III, Jupiter, Dan C., Thomas, J. Scott, and Papaconstantinou, Harry T.
Published: 2012
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23. Moving beyond teamwork in the operating room to facilitating mutual professional respect.

Author: Lin, Melody W., Papaconstantinou, Harry T., and White, Bobbie Ann Adair
Abstract: Psychological safety enables the interpersonal risk-taking necessary for providing safer patient care in the operating room (OR). Limited studies look at psychological safety in the OR from the perspectives of each highly specialized team member. Therefore, we investigated each member's perspective on the factors that influence psychological safety in the OR. Interviews were conducted with operative team members of a level 1 trauma center in central Texas. The interviews were transcribed, de-identified, and coded by two investigators independently, and thematic analysis was performed. Responses were collected from 21 participants representing all surgical team roles (attending surgeons, attending anesthesiologists, circulating nurses, nurse anesthetists, scrub techs, and residents). Circulating nurse responses were redacted for confidentiality (n = 1). Six major themes influencing psychological safety in the OR were identified. Psychological safety is essential to better, safer patient care. Establishing a climate of mutual respect and suspended judgment in an OR safe for learning will lay the foundation for achieving psychological safety in the OR. Team exercises in building rapport and mutual understanding are important starting points. [ABSTRACT FROM AUTHOR]
Published: 2023
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24. Improving Preoperative Communication and First Case On-Time Starts with the Surgical Flight Plan: A Pilot Study

Author: Falola, Reuben A., additional, Rodriguez-Unda, Nelson A., additional, Probe, Robert A., additional, Papaconstantinou, Harry T., additional, Saint-Cyr, Michel H., additional, and Altman, Andrew M., additional
Published: 2022
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25. Single-Incision Laparoscopic Right Colectomy: A Case-Matched Comparison with Standard Laparoscopic and Hand-Assisted Laparoscopic Techniques

Author: Papaconstantinou, Harry T., Sharp, Nicole, and Thomas, J. Scott
Published: 2011
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26. THE IMPACT OF A SURGICAL SAFETY CHECKLIST ON OPERATING ROOM TIME AND COST IN ROBOTIC ASSISTED LAPAROSCOPIC RADICAL PROSTATECTOMY: MP08-02

Author: Hudson, Tillman, Grant, Jordan, Tsai, Lawrence, Wagner, Kristofer, Papaconstantinou, Harry, Pruszynski, Jessica, and Lowry, Patrick
Published: 2016
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27. Outpatient colectomy—a dream or reality?

Author: Campbell, Stephen, primary, Fichera, Alessandro, additional, Thomas, Scott, additional, Papaconstantinou, Harry, additional, and Essani, Rahila, additional
Published: 2021
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28. Initial Outcomes of a Novel Irrigating Wound Protector for Reducing the Risk of Surgical Site Infection in Elective Colectomies

Author: Malek, Adil J., primary, Stafford, Susan V., additional, Papaconstantinou, Harry T., additional, and Thomas, Jimmy Scott, additional
Published: 2021
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29. The Impact of MRSA Colonization on Surgical Site Infection Following Major Gastrointestinal Surgery

Author: Ramirez, Marcela C., Marchessault, Michelle, Govednik-Horny, Cara, Jupiter, Daniel, and Papaconstantinou, Harry T.
Published: 2013
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30. Pilonidal Disease and Hidradenitis Suppurativa

Author: Papaconstantinou, Harry T., primary and Read, Thomas E., additional
Published: 2013
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31. Late Presentation of Intestinal Malrotation: An Argument for Elective Repair

Author: Moldrem, Amy W., Papaconstantinou, Harry, Broker, Harshal, Megison, Steve, and Jeyarajah, D. Rohan
Published: 2008
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32. Villous adenoma of the urethra

Author: Dowd, Katherine E., primary, Yang, Derek, additional, Papaconstantinou, Harry, additional, and Bird, Erin T., additional
Published: 2021
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33. Identification of apoptotic genes mediating TGF-[beta]/Smad3-induced cell death in intestinal epithelial cells using a genomic approach

Author: Cao, Yanna, Chen, Lu, Zhang, Weili, Liu, Yan, Papaconstantinou, Harry T., Bush, Craig R., Townsend, Courtney M., Jr., Thompson, E. Aubrey, and Ko, Tien C.
Subjects: Apoptosis -- Research, DNA microarrays -- Research, Transforming growth factors -- Research, Epithelial cells -- Genetic aspects, Epithelial cells -- Research, Biological sciences
Abstract: Transforming growth factor (TGF)-[beta]-dependent apoptosis is important in the elimination of damaged or abnormal cells from normal tissues in vivo. Previously, we have shown that TGF-[beta] inhibits the growth of rat intestinal epithelial (RIE)-1 cells. However, RIE-1 cells are relatively resistant to TGF[beta]-induced apoptosis due to a low endogenous Smad3-to-Akt ratio. Overexpression of Smad3 sensitizes RIE-1 cells (RIE-1/Smad3) to TGF-[beta]-induced apoptosis by altering the Smad3-to-Akt ratio in favor of apoptosis. In this study, we utilized a genomic approach to identify potential downstream target genes that are regulated by TGF-[beta]/Smad3. Total RNA samples were analyzed using Affymetrix oligonucleotide microarrays. We found that TGF-[beta] regulated 518 probe sets corresponding to its target genes. Interestingly, among the known apoptotic genes included in the microarray analyses, only caspase-3 was induced, which was confirmed by real-time RT-PCR. Furthermore, TGF-[beta] activated caspase-3 through protein cleavage. Upstream of caspase-3, TGF-[beta] induced mitochondrial depolarization, cytochrome c release, and cleavage of caspase-9, which suggests that the intrinsic apoptotic pathway mediates TGF-[beta]-induced apoptosis in RIE-1/Smad3 cells. apoptosis; Affymetrix oligonucleotide microarrays; caspases; transforming growth factor-[beta]
Published: 2007

34. Fissure-in-Ano

Author: Simmang, Clifford L., primary, Papaconstantinou, Harry T., additional, and Huber, Philip J., additional
Published: 2013
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35. Contributors

Author: Abbott, Andrea M., primary, Abcarian, Herand, additional, Abu-Jaish, Wasef, additional, Adams, David B., additional, Adams, Julie E., additional, Akman, Andrew S., additional, Alberts, Steven R., additional, Ando, Hisami, additional, Armstrong, Leonard, additional, Asamoah, Vivian A., additional, Asgeirsson, Theodor, additional, Ashley, Stanley W., additional, Avgerinos, Dimitrios, additional, Bailey, H. Randolph, additional, Bakhtawar, Humayun, additional, Bandla, Santhoshi, additional, Barlow, John M., additional, Baron, Todd H., additional, Andrade, Juan Camilo Barreto, additional, Bathla, Lokesh, additional, Beaty, Jennifer S., additional, Beck, David E., additional, Beddy, David, additional, Beekley, Alec C., additional, Behrns, Kevin E., additional, Ben-David, Kfir, additional, Bergman, Jacques, additional, Besselink, Marc, additional, Bharucha, Adil E., additional, Billeter, Adrian, additional, Black, Sylvester M., additional, Blatnik, Jeffrey A., additional, Bleday, Ronald, additional, Boland, Brendan J., additional, Boley, Scott J., additional, Bonavina, Luigi, additional, Bonin, Eduardo A., additional, Boostrom, Sarah Y., additional, Bower, Thomas C., additional, Brabender, Jan, additional, Brock, Malcolm V., additional, Buckley, Jill C., additional, Bulsiewicz, William J., additional, Burgess, Adele, additional, Burjonrappa, Sathyaprasad C., additional, Caban, Angel M., additional, Call, Jason A., additional, Callery, Mark P., additional, Cameron, John L., additional, Camilleri, Michael, additional, Carne, Peter W.G., additional, Carr, Jennifer C., additional, Paulson, Emily Carter, additional, Cassim, Riaz, additional, Castell, Donald O., additional, Cataldo, Peter, additional, Cemaj, Samuel, additional, Chandrasoma, Parakrama T., additional, Chang, George J., additional, Chaudhry, Vivek, additional, Chen, Herbert, additional, Cho, Clifford S., additional, Choi, Eugene A., additional, Chojnacki, Karen, additional, Choti, Michael A., additional, Christein, John D., additional, Christensen, Donald O., additional, Chukwumah, Chike V., additional, Chun, Albert K., additional, Cima, Robert R., additional, Clark, Clancy J., additional, Clavien, Pierre-Alain, additional, Cohen, Alfred M., additional, Cohen, Jeffrey, additional, Colquhoun, Steven D., additional, Coosemans, Willy, additional, Coppa, Gene F., additional, Cornwell, Edward E., additional, Cortez, Daniel A., additional, Costantini, Mario, additional, Craig, Daniel A., additional, Crookes, Peter F., additional, Cullen, Joseph J., additional, d’Audiffret, Alexandre, additional, Decaluwé, Herbert, additional, Decker, Georges, additional, Dehn, Thomas C.B., additional, De Leyn, Paul, additional, DeMeester, Steven R., additional, DeMeester, Tom R., additional, Demirjian, Aram N., additional, DeRoss, Anthony L., additional, de Santibañes, Eduardo, additional, Donohue, John H., additional, Dozois, Eric J., additional, Dunkin, Brian J., additional, Dunn, Stephen P., additional, Dunst, Christy M., additional, Duranceau, Andre, additional, Durrani, Noreen, additional, Dutkowski, Philipp, additional, Edil, Barish H., additional, Efron, Jonathan E., additional, El-Gohary, Yousef, additional, Ellison, E. Christopher, additional, Engum, Scott A., additional, Enker, Warren E., additional, Etzioni, David A., additional, Evans, Douglas B., additional, Fazio, Victor W., additional, Felix, Edward L., additional, Fink, Aaron S., additional, Fisher, James, additional, Fitzgibbons, Robert J., additional, Fogel, Evan L., additional, Fong, Yuman, additional, Ford, Debra H., additional, Forgione, Patrick, additional, Fortune, John B., additional, Fritze, Danielle M., additional, Fuchs, Karl-Hermann, additional, Funaki, Brian, additional, Gadacz, Thomas R., additional, Galandiuk, Susan, additional, Geller, David, additional, Gittes, George K., additional, Gitzelmann, Christopher A., additional, Godfrey, Tony E., additional, Goldblatt, Matthew I., additional, Gooszen, Hein G., additional, Gores, Gregory J., additional, Govil, Yogesh, additional, Grant, Kimberly, additional, Greer, Sarah E., additional, Grosfeld, Jay L., additional, Guillem, José G., additional, Hagen, Jeffrey A., additional, Hall, Jason F., additional, Hallemeier, Christopher L., additional, Hallowell, Peter T., additional, Harper, Amy P., additional, Hatzaras, Ioannis S., additional, Haut, Elliott R., additional, Havron, William S., additional, Heitmiller, Richard F., additional, Henderson, J. Michael, additional, Herlong, H. Franklin, additional, Hines, O. Joe, additional, Hirashima, Fuyuki, additional, Hofstetter, Wayne L., additional, Hölscher, Arnulf H., additional, Hompes, Roel, additional, Hoppo, Toshitaka, additional, Huber, Philip J., additional, Hull, Tracy, additional, Hungness, Eric S., additional, Hunter, John G., additional, Huprich, James E., additional, Hussain, Hero K., additional, Hyman, Neil, additional, Irani, Jennifer L., additional, Jackson, Emily T., additional, Jacobs, Danny O., additional, Jensen, Eric H., additional, Jephcott, Catherine, additional, Jobe, Blair A., additional, Johnston, Michael, additional, Jorden, Jeffrey, additional, Joyner, Paul, additional, Julien, Lucas A., additional, Kahrilas, Peter J., additional, Kaleya, Ronald, additional, Kashef, Elika, additional, Katz, Philip, additional, Kent, Tara, additional, Khati, Nadia J., additional, King, Jonathan C., additional, Kissane, Nicole A., additional, Klein, Andrew S., additional, Klinger, Dean E., additional, Knight, Jennifer, additional, Koleilat, Issam, additional, Kozol, Robert, additional, Krantz, Seth B., additional, Ladner, Daniela, additional, Langerman, Alexander, additional, Larson, David W., additional, Law, Simon, additional, Lawler, Leo P., additional, Lazaridis, Konstantinos N., additional, Lee, Yi-Horng, additional, Lee, Yoori, additional, Lefèvre, Jérémie H., additional, Lehman, Glen A., additional, Lerut, Toni, additional, Levi, David M., additional, Lidor, Anne, additional, Liebermann-Meffert, Dorothea, additional, Lillegard, Joseph, additional, Lillemoe, Keith D., additional, Litle, Virginia R., additional, Liu, Donald C., additional, Loftus, Edward V., additional, Lopez-Viego, Miguel, additional, Lord, Reginald V.N., additional, Lowe, Val J., additional, Lurje, Georg, additional, Lyons, Calvin, additional, MacCarty, Robert L., additional, Madoff, Robert D., additional, Maheshwari, Anurag, additional, Mahmoud, Najjia N., additional, Mahvi, David M., additional, Malagó, Massimo, additional, Mannal, Patrick, additional, Marohn, Michael R., additional, Maron, David J., additional, Martz, Joseph E., additional, Mathis, Kellie L., additional, Mathisen, Douglas, additional, Matthews, Jeffrey B., additional, McCahill, Laurence E., additional, McClusky, David A., additional, McFadden, David W., additional, McHenry, Lee, additional, McMurrick, Paul J., additional, Mee, Anthony S., additional, Meilahn, John E., additional, Michelassi, Fabrizio, additional, Miller, Robert C., additional, Miller, Thomas A., additional, Millis, J. Michael, additional, Misawa, Ryosuke, additional, Mittal, Sumeet, additional, Molmenti, Ernesto P., additional, Monson, John R.T., additional, Moore, Jesse, additional, Morgan, Katherine A., additional, Morse, Christopher R., additional, Mortensen, Neil J., additional, Mortenson, Melinda M., additional, Moxon, Ruth, additional, Mulholland, Michael W., additional, Nachmany, Ido, additional, Nafteux, Philippe, additional, Nagorney, David M., additional, Nandakumar, Govind, additional, Natarajan, Bala, additional, Nelson, Heidi, additional, Nicastro, Jeffrey M., additional, Nigam, Ankesh, additional, Nissen, Nicholas N., additional, Norton, Jeffrey A., additional, Nussbaum, Michael, additional, Nyberg, Scott, additional, Öberg, Stefan, additional, Oh, Daniel S., additional, Onesti, Jill K., additional, O’Rourke, Robert W., additional, Oto, Aytekin, additional, Otterson, Mary F., additional, Ouellette, James R., additional, Paidas, Charles N., additional, Pandolfino, John E., additional, Papaconstantinou, Harry T., additional, Pappas, Theodore N., additional, Parc, Yann, additional, Parker, Susan C., additional, Patti, Marco G., additional, Pegoli, Walter, additional, Pemberton, John H., additional, Peters, Jeffrey H., additional, Pham, Thai H., additional, Pillai, Lakshmikumar, additional, Pineda, Carlos E., additional, Pitt, Henry A., additional, Ponsky, Jeffrey L., additional, Posner, Mitchell C., additional, Postier, Russel G., additional, Prabhakaran, Sangeetha, additional, Prachand, Vivek N., additional, Que, Florencia G., additional, Radtke, Arnold, additional, Rai, Rudra, additional, Rakinic, Jan, additional, Rattner, David W., additional, Raymond, Daniel P., additional, Rice, Thomas W., additional, Richardson, J. David, additional, Riegler, Martin, additional, Roberts, John Paul, additional, Roberts, Patricia L., additional, Rodeberg, David A., additional, Roggin, Kevin K., additional, Rolandelli, Rolando, additional, Roman, Sabine, additional, Rosato, Ernest L., additional, Rosen, Michael J., additional, Ross, Andrew, additional, Rushing, Amy P., additional, Sabnis, Adheesh, additional, Saclarides, Theodore J., additional, Sagar, Peter M., additional, Sakorafas, George H., additional, Saltz, Leonard B., additional, Sarin, Shawn N., additional, Sarr, Michael G., additional, Sartorelli, Kennith, additional, Savas, Jeannie F., additional, Schirmer, Bruce, additional, Schmid-Tannwald, Christine, additional, Schneider, John G., additional, Schneider, Paul M., additional, Schnelldorfer, Thomas, additional, Schoetz, David J., additional, Schoppmann, Sebastian, additional, Schröder, Wolfgang, additional, Schulick, Richard D., additional, Senagore, Anthony, additional, Sepesi, Boris, additional, Shaheen, Nicholas J., additional, Sherman, Stuart, additional, Silberstein, Irene, additional, Simmang, Clifford L., additional, Singer, George, additional, Slakey, Douglas P., additional, Smith, Jason, additional, Smith, Jessica K., additional, Snyder, Christopher W., additional, Sonnenday, Christopher J., additional, Soper, Nathaniel J., additional, Sotiropoulos, George C., additional, Spechler, Stuart Jon, additional, Stanley, Andrew, additional, Statter, Mindy B., additional, Steele, Kimberley E., additional, Steinhagen, Emily, additional, Stocchi, Luca, additional, Sudakoff, Gary, additional, Sundaram, Abhishek, additional, Sundaram, Magesh, additional, Swanström, Lee L., additional, Swartz, Daniel E., additional, Takada, Tadahiro, additional, Tamm, Eric P., additional, Tavakkolizadeh, Ali, additional, Telford, Gordon L., additional, Thacker, Julie K. Marosky, additional, Theodoropoulos, Dimitra G., additional, Thomas, Michael S., additional, Thorson, Alan G., additional, Thurston, Kristy, additional, Tichansky, David S., additional, Tomizawa, Yutaka, additional, Traverso, L. William, additional, Trus, Thadeus, additional, Tsai, Susan, additional, Tsikitis, Vassiliki Liana, additional, Tsoraides, Steven, additional, Tutuian, Radu, additional, Tzakis, Andreas G., additional, Vallböhmer, Daniel, additional, Raemdonck, Dirk Van, additional, van Santvoort, Hjalmar, additional, Venbrux, Anthony C., additional, Vickers, Selwyn M., additional, Villar, Hugo V., additional, Villegas, Leonardo, additional, Wallace, James R., additional, Wallace, William D., additional, Wang, Huamin, additional, Wang, Kenneth K., additional, Watkins, James L., additional, Watson, Thomas J., additional, Waxman, Irving, additional, Weiser, Martin R., additional, Welch, John, additional, Welton, Mark L., additional, Wexner, Steven D., additional, White, Rebekah R., additional, Wick, Elizabeth C., additional, Wilson, Alison, additional, Winslow, Emily, additional, Witkowski, Piotr, additional, Wolff, Bruce G., additional, Wolfgang, Christopher L., additional, Wong, W. Douglas, additional, Worsey, Jonathan, additional, Wright, Cameron D., additional, Yadav, Bhupender, additional, Yeo, Charles J., additional, Yeung, Trevor M., additional, Yezhelyev, Max, additional, Yoo, Kyo-Sang, additional, You, Yi-Qian Nancy, additional, Young-Fadok, Tonia M., additional, Zacherl, Johannes, additional, Zaninotto, Giovanni, additional, Zeman, Merissa N., additional, Zimmerman, Pamela, additional, and Zuccaro, Gregory, additional
Published: 2013
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36. Characteristics and Survival Patterns of Solid Organ Transplant Patients Developing De Novo Colon and Rectal Cancer

Author: Papaconstantinou, Harry T., Sklow, Bradford, Hanaway, Michael J., Gross, Thomas G., Beebe, Thomas M., Trofe, Jennifer, Alloway, Rita R., Woodle, E. Steve, and Buell, Joseph F.
Published: 2004
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37. Resident-Championed Quality Improvement Provides Value: Confronting Prolonged Mechanical Ventilation

Author: Malek, Adil J., primary, Isbell, Claire L., additional, Mrdutt, Mary M., additional, Zamin, Syed A., additional, Allen, Erika M., additional, Coulson, Scott E., additional, Regner, Justin L., additional, and Papaconstantinou, Harry T., additional
Published: 2020
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38. Outpatient colectomy—a dream or reality?

Author: Campbell, Stephen, Fichera, Alessandro, Thomas, Scott, Papaconstantinou, Harry, and Essani, Rahila
Abstract: Whereas the advancement of minimally invasive surgical techniques and enhanced recovery after surgery (ERAS) pathways for partial colectomies has shortened postoperative length of stay, the ideal length of stay after partial colectomy with or without diverting loop ileostomy is still up for debate. This article examines the safety and efficacy of discharging select patients home from day surgery following partial colectomy. We performed a retrospective review of 7 patients who underwent partial colectomy at one tertiary care center from December 2020 to August 2021. None of our cases suffered complications such as anastomotic leak, surgical site infection, or bowel obstruction or required admission to the hospital. One patient was seen in the emergency department on postoperative day 1 for nausea and vomiting and was managed as an outpatient. A second patient required a fluid bolus in the clinic for high ileostomy output. In conclusion, our study suggests that appropriately selected patients can be successfully managed in the outpatient setting without increased complications following partial colectomy when preoperative preparation and education are put in place alongside our colon ERAS pathway and minimally invasive surgical techniques. [ABSTRACT FROM AUTHOR]
Published: 2022
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39. Prevention of mucosal atrophy: Role of glutamine and caspases in apoptosis in intestinal epithelial cells

Author: Papaconstantinou, Harry T., Chung, Dai H., Zhang, Weiping, Ansari, Naseem H., Hellmich, Mark R., Townsend, Jr., Courtney M., and Ko, Tien C.
Published: 2000
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40. Targeting molecular pathways with camptothecin as novel therapy for gastric cancer

Author: Litvak, David A., Papaconstantinou, Harry T., Evers, B. Mark, and Townsend, Jr., Courtney M.
Published: 1999
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41. Single-incision laparoscopic colectomy for cancer: Assessment of oncologic resection and short-term outcomes in a case-matched comparison with standard laparoscopy

Author: Papaconstantinou, Harry T. and Thomas, Scott J.
Published: 2011
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42. Chapter 159 - Fissure-in-Ano

Author: Essani, Rahila and Papaconstantinou, Harry T.
Published: 2019
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43. Identifying Preoperative Risk Factors Associated with Prolonged Mechanical Ventilation in Elective Surgical Patients: First Steps to Improved Risk Stratification

Author: Malek, Adil J., primary, Zamin, Syed A., additional, Sager, Lauren, additional, Regner, Justin L., additional, Papaconstantinou, Harry T., additional, and Isbell, Claire L., additional
Published: 2019
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44. Screening Methods for High-Grade Dysplasia in Patients with Anal Condyloma 1

Author: Papaconstantinou, Harry T., Lee, Augustine J., Simmang, Clifford L., Ashfaq, Raheela, Gokaslan, Sefik T., Sokol, Saul, Huber, Philip J., Jr., and Gregorcyk, Sharon G.
Published: 2005
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