520 results on '"Paoletti, L."'
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2. First light of BEaTriX, the new testing facility for the modular X-ray optics of the ATHENA mission
- Author
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Basso, S., Salmaso, B., Spiga, D., Ghigo, M., Vecchi, G., Sironi, G., Cotroneo, V., Conconi, P., Redaelli, E., Bianco, A., Pareschi, G., Tagliaferri, G., Sisana, D., Pelliciari, C., Fiorini, M., Incorvaia, S., Uslenghi, M., Paoletti, L., Ferrari, C., Lolli, R., Zappettini, A., del Rio, M. Sanchez, Parodi, G., Burwitz, V., Rukdee, S., Hartner, G., Müller, T., Schmidt, T., Langmeier, A., Ferreira, D. Della Monica, Massahi, S., Gellert, N. C., Christensen, F., Bavdaz, M., Ferreira, I., Collon, M., Vacanti, G., and Barrière, N. M.
- Subjects
Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The Beam Expander Testing X-ray facility (BEaTriX) is a unique X-ray apparatus now operated at the Istituto Nazionale di Astrofisica (INAF), Osservatorio Astronomico di Brera (OAB), in Merate, Italy. It has been specifically designed to measure the point spread function (PSF) and the effective area (EA) of the X-ray mirror modules (MMs) of the Advanced Telescope for High-ENergy Astrophysics (ATHENA), based on silicon pore optics (SPO) technology, for verification before integration into the mirror assembly. To this end, BEaTriX generates a broad, uniform, monochromatic, and collimated X-ray beam at 4.51 keV. [...] In BEaTriX, a micro-focus X-ray source with a titanium anode is placed in the focus of a paraboloidal mirror, which generates a parallel beam. A crystal monochromator selects the 4.51 keV line, which is expanded to the final size by a crystal asymmetrically cut with respect to the crystalline planes. [...] After characterization, the BEaTriX beam has the nominal dimensions of 170 mm x 60 mm, with a vertical divergence of 1.65 arcsec and a horizontal divergence varying between 2.7 and 3.45 arcsec, depending on the monochromator setting: either high collimation or high intensity. The flux per area unit varies from 10 to 50 photons/s/cm2 from one configuration to the other. The BEaTriX beam performance was tested using an SPO MM, whose entrance pupil was fully illuminated by the expanded beam, and its focus was directly imaged onto the camera. The first light test returned a PSF and an EA in full agreement with expectations. As of today, the 4.51 keV beamline of BEaTriX is operational and can characterize modular X-ray optics, measuring their PSF and EA with a typical exposure of 30 minutes. [...] We expect BEaTriX to be a crucial facility for the functional test of modular X-ray optics, such as the SPO MMs for ATHENA., Comment: Accepted on 29 June 2022 for publication in Astronomy & Astrophysics, Sect. 13, Astronomical instrumentation of Astronomy and Astrophysics. Version after language correction
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- 2022
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3. Surface-guided DIBH radiotherapy for left breast cancer: impact of different thresholds on intrafractional motion monitoring and DIBH stability
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Gnerucci, A., Esposito, M., Ghirelli, A., Pini, S., Paoletti, L., Barca, R., Fondelli, S., Alpi, P., Grilli, B., Rossi, F., Scoccianti, S., and Russo, S.
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- 2023
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4. Hyaluronan-estradiol nanogels as potential drug carriers to target ER+ breast cancer cell line
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Paoletti, L., Zoratto, N., Benvenuto, M., Nardozi, D., Angiolini, V., Mancini, P., Masuelli, L., Bei, R., Frajese, G.V., Matricardi, P., Nalli, M., and Di Meo, C.
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- 2023
- Full Text
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5. OC.06.2: POTENTIALOFA NATURAL COMPOUNDAS HEDGEHOG PATHWAY INHIBITOR FOR THE TREATMENT OF INTRAHEPATIC CHOLANGIOCARCINOMA
- Author
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Paradiso, S., primary, Carpino, G., additional, Quaglio, D., additional, Ghirga, F., additional, Di Meo, C., additional, Paoletti, L., additional, De Luca, T., additional, Franchitto, M., additional, Di Marcotullio, L., additional, Infante, P., additional, Gaudio, E., additional, Alvaro, D., additional, and Cardinale, V., additional
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- 2024
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6. The CYGNO/INITIUM experiment
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F. D. Amaro, E. Baracchini, L. Benussi , S. Bianco, C. Capoccia, M. Caponero, D. Santos Cardoso, G. Cavoto, A. Cortez, I. A. Costa, E. Dané, G. Dho, F. Di Giambattista, E. Di Marco, G. D’Imperio, F. Iacoangeli, H. P. L. Jùnior, G. S. P. Lopes, G. Maccarrone, R. D. P. Mano, R. R. M. Gregorio, D. J. G. Marques, G. Mazzitelli, A. G. McLean, A. Messina, C. M. B. Monteiro, R. A. Nobrega, I. Fonseca Pains, E. Paoletti, L. Passamonti, S. Pelosi, F. Petrucci, S. Piacentini, D. Piccolo, D. Pierluigi, D. Pinci, A. Prajapati, F. Renga, R. J. C. Roque, F. Rosatelli, A. Russo, J. M. F. dos Santos, G. Saviano, N. J. C. Spooner, R. Tesauro, S. Tommasini, S. Torelli
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Physics ,QC1-999 - Abstract
The CYGNO project for the development of a high precision optical readout gaseous TPC for directional Dark Matter search and solar neutrino spectroscopy will be presented. It is to be hosted at Laboratori Nazionali del Gran Sasso. CYGNO peculiar features are the use of sCMOS cameras and PMTs coupled to GEMs amplification of a helium-based gas mixture at atmospheric pressure, in order to achieve 3D tracking with head tail capability and background rejection down to O(keV) energy, to boost sensitivity to low WIMP masses. The latest R&D results within the CYGNO project will be discussed along with the underground installation and operation of a 50 l prototype, soon to be followed by a O(1) m3 experiment demonstrator in 2024-2026. The latest results on the negative ion drift operation at atmospheric pressure within CYGNO optical readout approach will be illustrated, which is the aim of the ERC Consolidator Grant project INITIUM.
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- 2023
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7. Underprescription of medications in older adults: causes, consequences and solutions—a narrative review
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Lombardi, F., Paoletti, L., Carrieri, B., Dell’Aquila, G., Fedecostante, M., Di Muzio, M., Corsonello, A., Lattanzio, F., and Cherubini, A.
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- 2021
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8. Correction: Epidemiology and outcomes of early-onset AKI in COVID-19-related ARDS in comparison with non-COVID-19-related ARDS: insights from two prospective global cohort studies (Critical Care, (2023), 27, 1, (3), 10.1186/s13054-022-04294-5)
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McNicholas B. A., Mcnicholas, B, Rezoagli, E, Simpkin, A, Khanna, S, Suen, J, Yeung, P, Brodie, D, Bassi, G, Pham, T, Bellani, G, Fraser, J, Laffey, J, Al-Dabbous, T, Alfoudri, H, Shamsah, M, Alhadad, Q, Hanan, M, Elapavaluru, S, Berg, A, Horn, C, Abdelhalim, A, Amer, A, Elnaggar, C, Hassan, A, Abdelaziz, A, Abdelhalim, M, Orabi, Y, Alaraji, Z, Muhaisen, M, Almasri, L, Mustafa, D, Hamdan, S, Al-Saba'a, Y, Dalloul, Z, Alkahlout, M, Jaber, H, Aldabbourosama, O, Hussein, A, Emad, Z, Khaled, S, Mohamed, N, Hassanin, E, Hamdi, A, Ragab, A, Azizeldin, M, Mayasi, Y, Schroll, S, Meyer, D, Velazco, J, Ploskanych, L, Fikes, W, Bagewadi, R, Dao, M, White, H, Laviena, A, Ehlers, A, Shalabi-McGuire, M, Witt, T, Grazioli, L, Lorini, L, Grandin, E, Nunez, J, Reyes, T, O'Briain, D, Hunter, S, Ramanan, M, Affleck, J, Veerendra, H, Rai, S, Russell-Brown, J, Nourse, M, Joseph, M, Mitchell, B, Tenzer, M, Abe, R, Cho, H, Jeong, I, Rahman, N, Kakar, V, Sun, H, Hanley, A, Brozzi, N, Mehkri, O, Krishnan, S, Duggal, A, Houltham, S, Graf, J, Diaz, R, Orrego, R, Delgado, C, Gonzalez, J, Sanchez, M, Piagnerelli, M, Sarrazin, J, Zabert, G, Espinosa, L, Delgado, P, Delgado, V, Rincon, D, Yanten, A, Duque, M, Abouelmagd, K, Elhazmi, A, Al-Hudaib, A, Javidfar, J, Callahan, M, Dong, A, D'Orleans, C, Taufik, M, Wardoyo, E, Gunawan, M, Trisnaningrum, N, Irawany, V, Rayhan, M, Panigada, M, Pesenti, A, Zanella, A, Grasselli, G, Colombo, S, Martinet, C, Florio, G, Antonelli, M, Carelli, S, Grieco, D, Asaki, M, Hoshino, K, Salazar, L, Monsalve, M, Cosgrave, D, Atif, M, Qutishat, F, Laffey, C, Van Der Walt, M, Mccaffrey, J, Bone, A, Hakeem, Y, Winearls, J, Tallott, M, Thomson, D, Joubert, I, Arnold-Day, C, Piercy, J, van Zyl Smit, R, Miller, M, Seymour, L, van Heyningen, F, Teyangesikayi, G, Fredericks, D, Hssain, A, Aliudin, J, Alqahtani, A, Mohamed, K, Mohamed, A, Tan, D, Villanueva, J, Zaqout, A, Kurtzman, E, Ademi, A, Dobrita, A, El Aoudi, K, Segura, J, Giwangkancana, G, Ohshimo, S, Osatnik, J, Joosten, A, Torres, A, Yang, M, Motos, A, Luna, C, Arancibia, F, Williams, V, Noel, A, Luque, N, Fantini, M, Garcia, R, Alvarez, E, Greti, A, Ceccato, A, Sanchez, A, Vazquez, A, Roche-Campo, F, Franch-Llasat, D, Tuazon, D, Amato, M, Cassimiro, L, Pola, F, Ribeiro, F, Fonseca, G, Dalton, H, Desai, M, Osborn, E, Deeb, H, Arcadipane, A, Martucci, G, Panarello, G, Vitiello, S, Bianco, C, Occhipinti, G, Rossetti, M, Cuffaro, R, Cho, S, Whitman, G, El Sayed, M, Mokhtar, W, El-Shenawy, E, Shimizu, H, Moriyama, N, Kim, J, Kitamura, N, Gebauer, J, Yokoyama, T, Al-Fares, A, Buabbas, S, Alamad, E, Alawadhi, F, Alawadi, K, Khalefa, M, Al Ajeel, N, Aly, M, Al-Saleh, A, Naanouh, A, Elshourbgy, A, Gad, M, Elrazaz, R, Khadadah, I, Almumin, A, Altarakma, H, Albannay, H, Alsaleh, M, Radwan, M, Saadallah, I, Tanaka, H, Hashimoto, S, Yamazaki, M, Oh, T, Epler, M, Forney, C, Kruse, L, Feister, J, Williamson, J, Grobengieser, K, Gnall, E, Golden, S, Caroline, M, Shapiro, T, Karaj, C, Thome, L, Sher, L, Vanderland, M, Welch, M, Mcdermott, S, Brain, M, Mineall, S, Unwin, M, Chen, L, Trezise, T, Mckeon, L, Kimura, D, Brazzi, L, Sales, G, Montrucchio, G, Ogston, T, Nagpal, D, Fischer, K, Lorusso, R, van Bussell, B, De Piero, M, Mariani, S, Rangappa, R, Shetty, R, Rai, P, Ganesan, A, Esperatti, M, Fuentes, N, Gonzalez, M, Carton, E, Sen, A, Palacios, A, Rainey, D, Samoukoviv, G, Campisi, J, Durham, L, Neumann, E, Seefeldt, C, Falcucci, O, Emmrich, A, Guy, J, Johns, C, Potzner, K, Zimmermann, C, Espinal, A, Buchtele, N, Schwameis, M, Korhnfehl, A, Brock, R, Staudinger, T, Stecher, S, Barnikel, M, Anton, S, Pawlikowski, A, Zaaqoq, A, Galloway, L, Merley, C, Nichol, A, Csete, M, Quesada, L, Saba, I, Kasugai, D, Hiraiwa, H, Tanaka, T, Marwali, E, Purnama, Y, Dewayanti, S, Ardiyan, Juzar, D, Siagian, D, Chen, Y, Ogino, M, Nasa, P, Matthew, C, Majeed, N, Ratsep, I, Post, A, Sillaots, P, Krund, A, Lehiste, M, Lepik, T, Manetta, F, Mihelis, E, Sarmiento, I, Narasimhan, M, Varrone, M, Komats, M, Garcia-Diaz, J, Harmon, C, Satyapriya, S, Bhatt, A, Mokadam, N, Uribe, A, Gonzalez, A, Shi, H, Mckeown, J, Pasek, J, Fiorda, J, Echeverria, M, Moreno, R, Zakhary, B, Cavana, M, Cucino, A, Foti, G, Giani, M, Fumagalli, B, Chiumello, D, Castagna, V, Dell'Amore, A, Navalesi, P, Shum, H, Vuysteke, A, Usman, A, Acker, A, Smood, B, Mergler, B, Sertic, F, Subramanian, M, Sperry, A, Rizer, N, Burhan, E, Rasmin, M, Akmal, E, Sitompul, F, Lolong, N, Naivedh, B, Erickson, S, Barrett, P, Dean, D, Daugherty, J, Loforte, A, Khan, I, Quraishi, M, Desantis, O, So, D, Kandamby, D, Mandei, J, Natanael, H, Yudhalantang, E, Lantang, A, Wijaya, S, Jung, A, Ng, G, Ng, W, Ng, P, Fang, S, Tabah, A, Ratcliffe, M, Duroux, M, Alajeeli, A, Tarhabat, A, Adachi, S, Nakao, S, Blanco, P, Prieto, A, Sanchez, J, Nicholson, M, Butt, W, Serratore, A, Delzoppo, C, Janin, P, Yarad, E, Totaro, R, Coles, J, Pujo, B, Balk, R, Vissing, A, Kapania, E, Hays, J, Fox, S, Yantosh, G, Mishin, P, Yuliarto, S, Santoso, K, Djajalaksana, S, Fatoni, A, Fukuda, M, Liu, K, Pelosi, P, Battaglini, D, Jimenez, J, Bastos, D, Gaiao, S, Rusmawatiningtyas, D, Cho, Y, Lee, S, Kawasaki, T, Munshi, L, Sakiyalak, P, Nitayavardhana, P, Elagili, M, Salem, T, Seitz, T, Arora, R, Kent, D, Marino, D, Parwar, S, Cheng, A, Miller, J, Fujitani, S, Shimizu, N, Madhok, J, Owyang, C, Buscher, H, Reynolds, C, Maasikas, O, Aleksanbeljantsev, Mihnovits, V, Akimoto, T, Aizawa, M, Horibe, K, Onodera, R, Hodgson, C, Burrell, A, Young, M, George, T, Shekar, K, Mcguinness, N, Irvine, L, Flynn, B, Endo, T, Sugiyama, K, Shimizu, K, Fan, E, Exconde, K, Ichiba, S, Binnawara, M, Lussier, L, Lotz, G, Malfertheiner, M, Maier, L, Dreier, E, Kusumastuti, N, Mccloskey, C, Dabaliz, A, Elshazly, T, Smith, J, Szuldrzynski, K, Bielanski, P, Wille, K, Murthy, S, Parhar, K, Fiest, K, Codan, C, Shahid, A, Fayed, M, Evans, T, Gutierrez, A, Song, T, Rose, R, Bennett, S, Richardson, D, Peek, G, Arora, L, Rappapport, K, Rudolph, K, Sibenaller, Z, Stout, L, Walter, A, Herr, D, Vedadi, N, Bartlett, R, Thompson, S, Hoffman, J, Ying, X, Williams, B, Sanchez, E, Akwani, C, Kennedy, R, Elhadi, M, Griffee, M, Mone, M, Ciullo, A, Kida, Y, Roca, R, Riera, J, Contreras, S, Alegre, C, Kay, C, Fischer, I, Renner, E, Taniguci, H, Lee, J, Plotkin, D, Citarella, B, Merson, L, Hartley, E, Lubis, B, Ikeyama, T, Alhamad, A, Fathi, M, Hadhoud, M, Alhouri, H, Mechi, A, Alyasiri, M, Elsaid, M, Shahla, H, Bhaskar, B, Jung, J, Mcguinness, S, Eastwood, G, Marta, S, Guarracino, F, Gerle, S, Coxon, E, Claro, B, Eleisawy, M, Osama, H, Loverde, D, Patil, N, Parrini, V, Mcbride, A, Negaard, K, Ratsch, A, Uribe, J, Peris, A, Sanders, M, Emerson, D, Kamal, M, Faida, H, Povoa, P, Francis, R, Cherif, A, Joseph, S, Di Nardo, M, Heard, M, Kyle, K, Blackwell, R, Ouyahia, A, Biston, P, Jeong, H, Smith, R, Prawira, Y, Garcia, A, Salterain, N, Meyns, B, Elnasser, M, Moreno, M, Walia, R, Mehta, A, Schweda, A, Williams, M, Emadamkhatirah, Kim, K, Assad, A, Giraldo, E, Karolak, W, Balik, M, Pocock, E, Gajkowski, E, Masafumi, K, Barrett, N, Takeyama, Y, Park, S, Amin, F, Andriyani, F, Sudakevych, S, Schnur, J, Vera, M, Cornejo, R, Schwarz, P, Mardini, A, de Paula, T, Neto, A, Villoldo, A, Colafranceschi, A, Iglesias, A, Granjean, J, Melro, L, Romualdo, G, Gaia, D, Souza, H, Galas, F, Mendiluce, R, Sosa, A, Martinez, I, Kurosawa, H, Almoshantaf, M, Salgado, J, Hugi-Mayr, B, Charbonneau, E, Barzilai, V, Monteiro, V, de Souza, R, Harper, M, Siddig, N, Suzuki, H, Adams, C, Brieva, J, Khamees, A, Graige, F, Supriatna, M, Nyale, G, Eltatar, F, Fatani, J, Baeissa, H, Masri, A, Rabie, A, Hui, M, Yamane, M, Jung, H, Margaret, A, Nacpil, N, Ruck, K, Bakken, R, Jara, C, Felton, T, Tharwat, S, Berra, L, Shah, B, Chakraborty, A, Cardona, M, Capatos, G, Akkanti, B, Orija, A, Jain, H, Ito, A, Muftah, M, Housni, B, Aldhalia, A, Low, S, Iihara, K, Chavez, J, Ramanathan, K, Naidoo, K, Seppelt, I, Vandyk, M, Macdonald, S, Hafez, W, Mcgregor, R, Siebenaler, T, Flynn, H, Lofton, K, Aokage, T, Kvirkvelia, B, Shigemitsu, K, Moscatelli, A, Fiorentino, G, Baumgaertel, M, Mba, S, Assy, J, Hutahaean, A, Roush, H, Sichting, K, Alessandri, F, Burns, D, Alkhubouli, T, Nasrallah, A, Salt, G, Garabedian, C, Millar, J, Sim, M, Mattke, A, Mcauley, D, Tadili, J, Frenzel, T, Bar-Lavie, Y, Ortiz, A, Stone, J, Attokaran, A, Farquharson, M, Patel, B, Gunning, D, Baillie, K, Adem, S, Watson, P, Tamai, K, Sajinadiyasa, G, Kanyawati, D, Salgado, M, Sassine, A, Yudo, B, Mccaul, S, Lee, B, Afek, A, Iwashita, Y, Fadlalmola, H, Semedi, B, Mansour, N, Metiva, J, Van Belle, N, Martin-Loeches, I, Al-Sadawi, M, Kirakli, C, Shimaa, A, Abdurraouf, A, Ivatt, L, Moharam, S, Woon, C, Kang, H, Smith, T, James, E, Al-Rawas, N, Almjersah, A, Iwasaki, Y, Ashour, H, Embarek, H, King-Chung, K, Gudzenko, V, Taccone, F, Perdhana, F, Lamarche, Y, Ribeiro, J, Bradic, N, Van den Bossche, K, Lansink, O, Singh, G, Debeuckelaere, G, Stelfox, H, Yi, C, Elia, J, Tribble, T, Shankar, S, Padmanabhan, R, Hallinan, B, Paoletti, L, Leyva, Y, Fykuda, T, Badulak, J, Koch, J, Janowaik, L, Hackman, A, Hernandez, D, Osofsky, J, Donadello, K, Lawang, A, Fine, J, Davidson, B, Abdehaleem, I, McNicholas B. A., Rezoagli E., Simpkin A. J., Khanna S., Suen J. Y., Yeung P., Brodie D., Bassi G. L., Pham T., Bellani G., Fraser J. F., Laffey J., Al-Dabbous T., Alfoudri H., Shamsah M., Alhadad Q., Hanan M., Elapavaluru S., Berg A., Horn C., Abdelhalim A. R. M. E., Amer A. E., Elnaggar C. O. R., Hassan A. A., Abdelaziz A., Abdelhalim M., Orabi Y. S. S. A., Alaraji Z. A., Muhaisen M. R., Almasri L., Mustafa D., Hamdan S., Al-Saba'a Y., Dalloul Z., Alkahlout M., Jaber H., Aldabbourosama O., Hussein A. A. R. M., Emad Z. K., Khaled S., Mohamed N., Hassanin E., Hamdi A., Ragab A., Azizeldin M. G., Mayasi Y., Schroll S., Meyer D., Velazco J., Ploskanych L., Fikes W., Bagewadi R., Dao M., White H., Laviena A. B., Ehlers A., Shalabi-McGuire M., Witt T., Grazioli L., Lorini L., Grandin E. W., Nunez J., Reyes T., O'Briain D., Hunter S., Ramanan M., Affleck J., Veerendra H. H., Rai S., Russell-Brown J., Nourse M., Joseph M., Mitchell B., Tenzer M., Abe R., Cho H. J., Jeong I. S., Rahman N., Kakar V., Sun H., Hanley A., Brozzi N., Mehkri O., Krishnan S., Duggal A., Houltham S., Graf J., Diaz R., Orrego R., Delgado C., Gonzalez J., Sanchez M. S., Piagnerelli M., Sarrazin J. V., Zabert G., Espinosa L., Delgado P., Delgado V., Rincon D. F. B., Yanten A. M. M., Duque M. B., Abouelmagd K., Elhazmi A., Al-Hudaib A., Javidfar J., Callahan M., Dong A., D'Orleans C. C., Taufik M. A., Wardoyo E. Y., Gunawan M., Trisnaningrum N. S., Irawany V., Rayhan M., Panigada M., Pesenti A., Zanella A., Grasselli G., Colombo S., Martinet C., Florio G., Antonelli M., Carelli S., Grieco D. L., Asaki M., Hoshino K., Salazar L., Monsalve M. A. M., McNicholas B., Cosgrave D., Atif M., Qutishat F., Laffey C., Van Der Walt M., McCaffrey J., Bone A., Hakeem Y., Winearls J., Tallott M., Thomson D., Joubert I., Arnold-Day C., Piercy J., van Zyl Smit R., Miller M., Seymour L., van Heyningen F., Teyangesikayi G., Fredericks D., Hssain A. A., Aliudin J., Alqahtani A. -R., Mohamed K., Mohamed A., Tan D., Villanueva J., Zaqout A., Kurtzman E., Ademi A., Dobrita A., El Aoudi K., Segura J., Giwangkancana G., Ohshimo S., Osatnik J., Joosten A., Torres A., Yang M., Motos A., Luna C., Arancibia F., Williams V., Noel A., Luque N., Fantini M., Garcia R. N. J., Alvarez E. C., Greti A., Ceccato A., Sanchez A., Vazquez A. L., Roche-Campo F., Franch-Llasat D., Tuazon D., Amato M., Cassimiro L., Pola F., Ribeiro F., Fonseca G., Dalton H., Desai M., Osborn E., Deeb H., Arcadipane A., Martucci G., Panarello G., Vitiello S., Bianco C., Occhipinti G., Rossetti M., Cuffaro R., Cho S. -M., Whitman G., El Sayed M., Mokhtar W., El-Shenawy E., Shimizu H., Moriyama N., Kim J. -B., Kitamura N., Gebauer J., Yokoyama T., Al-Fares A., Buabbas S., Alamad E., Alawadhi F., Alawadi K., Khalefa M. A., Al Ajeel N. A. A., Aly M. F., Al-Saleh A., Naanouh A., Elshourbgy A. M., Gad M. Y., ElRazaz R. M., Khadadah I., Almumin A. M., Altarakma H., Albannay H., Alsaleh M. K., Radwan M. S. A., Saadallah I. A., Tanaka H., Hashimoto S., Yamazaki M., Oh T. -H., Epler M., Forney C., Kruse L., Feister J., Williamson J., Grobengieser K., Gnall E., Golden S., Caroline M., Shapiro T., Karaj C., Thome L., Sher L., Vanderland M., Welch M., McDermott S., Brain M., Mineall S., Unwin M., Chen L., Trezise T., McKeon L., Kimura D., Brazzi L., Sales G., Montrucchio G., Ogston T., Nagpal D., Fischer K., Lorusso R., van Bussell B., De Piero M. E., Mariani S., Rangappa R., Shetty R. M., Rai P. S., Ganesan A., Esperatti M., Fuentes N. A., Gonzalez M. E., Carton E. G., Sen A., Palacios A., Rainey D., Samoukoviv G., Campisi J., Durham L., Neumann E., Seefeldt C., Falcucci O., Emmrich A., Guy J., Johns C., Potzner K., Zimmermann C., Espinal A., Buchtele N., Schwameis M., Korhnfehl A., Brock R., Staudinger T., Stecher S. -S., Barnikel M., Anton S., Pawlikowski A., Zaaqoq A., Galloway L. A., Merley C., Nichol A., Csete M., Quesada L., Saba I., Kasugai D., Hiraiwa H., Tanaka T., Marwali E., Purnama Y., Dewayanti S. R., Juzar D. A., Siagian D., Chen Y. -S., Ogino M., Nasa P., Matthew C., Majeed N. A., Ratsep I., Post A. -M., Sillaots P., Krund A., Lehiste M. -H., Lepik T., Manetta F., Mihelis E., Sarmiento I. C., Narasimhan M., Varrone M., Komats M., Garcia-Diaz J., Harmon C., Satyapriya S. V., Bhatt A., Mokadam N. A., Uribe A., Gonzalez A., Shi H., McKeown J., Pasek J., Fiorda J., Echeverria M., Moreno R., Zakhary B., Cavana M., Cucino A., Foti G., Giani M., Fumagalli B., Chiumello D., Castagna V., Dell'Amore A., Navalesi P., Shum H. -P., Vuysteke A., Usman A., Acker A., Smood B., Mergler B., Sertic F., Subramanian M., Sperry A., Rizer N., Burhan E., Rasmin M., Akmal E., Sitompul F., Lolong N., Naivedh B., Erickson S., Barrett P., Dean D., Daugherty J., Loforte A., Khan I., Quraishi M. A., DeSantis O., So D., Kandamby D., Mandei J. M., Natanael H., YudhaLantang E., Lantang A., Wijaya S. O., Jung A., Ng G., Ng W. Y., Ng P. Y., Fang S., Tabah A., Ratcliffe M., Duroux M., Alajeeli A., Tarhabat A., Adachi S., Nakao S., Blanco P., Prieto A., Sanchez J., Nicholson M., Butt W., Serratore A., Delzoppo C., Janin P., Yarad E., Totaro R., Coles J., Pujo B., Balk R., Vissing A., Kapania E., Hays J., Fox S., Yantosh G., Mishin P., Yuliarto S., Santoso K. H., Djajalaksana S., Fatoni A. Z., Fukuda M., Liu K., Pelosi P., Battaglini D., Jimenez J. F. M., Bastos D., Gaiao S., Rusmawatiningtyas D., Cho Y. -J., Lee S. H., Kawasaki T., Munshi L., Sakiyalak P., Nitayavardhana P., Elagili M. B., Salem T. A. A., Seitz T., Arora R., Kent D., Marino D., Parwar S., Cheng A., Miller J., Fujitani S., Shimizu N., Madhok J., Owyang C., Buscher H., Reynolds C., Maasikas O., AleksanBeljantsev, Mihnovits V., Akimoto T., Aizawa M., Horibe K., Onodera R., Hodgson C., Burrell A., Young M., George T., Shekar K., McGuinness N., Irvine L., Flynn B., Endo T., Sugiyama K., Shimizu K., Fan E., Exconde K., Ichiba S., Binnawara M., Lussier L., Lotz G., Malfertheiner M., Maier L., Dreier E., Kusumastuti N. P., McCloskey C., Dabaliz A. -A., Elshazly T. B., Smith J., Szuldrzynski K. S., Bielanski P., Wille K., Murthy S., Parhar K. K. S., Fiest K. M., Codan C., Shahid A., Fayed M., Evans T., Garcia R., Gutierrez A., Song T., Rose R., Bennett S., Richardson D., Peek G., Arora L., Rappapport K., Rudolph K., Sibenaller Z., Stout L., Walter A., Herr D., Vedadi N., Bartlett R., Thompson S., Hoffman J., Ying X., Williams B., Sanchez E., Akwani C., Kennedy R., Elhadi M., Griffee M., Mone M., Ciullo A., Kida Y., Roca R. F., Riera J. I., Contreras S., Alegre C., Kay C., Fischer I., Renner E., Taniguci H., Lee J., Plotkin D., Citarella B. W., Merson L., Hartley E., Lubis B., Ikeyama T., Alhamad A., Fathi M., Hadhoud M. M., Alhouri H., Mechi A., Alyasiri M. S., Elsaid M. Z. A., Shahla H., Bhaskar B., Jung J. -S., McGuinness S., Eastwood G., Marta S. R., Guarracino F., Gerle S., Coxon E., Claro B., Eleisawy M., Osama H., Loverde D., Patil N., Parrini V., McBride A., Negaard K., Ratsch A., Uribe J. D., Peris A., Sanders M., Emerson D., Kamal M., Faida H., Povoa P., Francis R., Cherif A., Joseph S., Di Nardo M., Heard M., Kyle K., Blackwell R. A., Ouyahia A., Biston P., Jeong H. W., Smith R., Prawira Y., Garcia A. H., Salterain N., Meyns B., Elnasser M., Moreno M., Walia R., Mehta A., Schweda A., Williams M., EmadAmkhatirah, Kim K. H., Assad A., Giraldo E., Karolak W., Balik M., Pocock E., Gajkowski E., Masafumi K., Barrett N., Takeyama Y., Park S., Amin F., Andriyani F. M., Sudakevych S., Schnur J., Vera M., Cornejo R., Schwarz P., Mardini A. C., de Paula T., Neto A. S., Villoldo A., Colafranceschi A. S., Iglesias A. U., Granjean J., Melro L. M. G., Romualdo G. F., Gaia D., Souza H., Galas F., Mendiluce R. M., Sosa A., Martinez I., Kurosawa H., Almoshantaf M. B., Salgado J., Hugi-Mayr B., Charbonneau E., Barzilai V. S., Monteiro V., de Souza R. R., Harper M., Siddig N., Suzuki H., Adams C., Brieva J., Khamees A., Graige F., Supriatna M., Nyale G., Eltatar F. S., Fatani J., Baeissa H., Masri A. A. L., Rabie A., Hui M. Y., Yamane M., Jung H., Margaret A. M., Nacpil N., Ruck K., Bakken R., Jara C., Felton T., Tharwat S., Berra L., Shah B., Chakraborty A., Cardona M., Capatos G., Akkanti B., Orija A., Jain H., Ito A., Muftah M., Housni B., Aldhalia A., Low S., Iihara K., Chavez J., Ramanathan K., Naidoo K., Seppelt I., VanDyk M., MacDonald S., Hafez W., McGregor R., Siebenaler T., Flynn H., Lofton K., Aokage T., Kvirkvelia B., Shigemitsu K., Moscatelli A., Fiorentino G., Baumgaertel M., Mba S. E., Assy J., Hutahaean A., Roush H., Sichting K. A., Alessandri F., Burns D., Alkhubouli T. H., Nasrallah A., Salt G., Garabedian C. P., Millar J., Sim M., Mattke A., McAuley D., Tadili J., Frenzel T., Bar-Lavie Y., Ortiz A. B., Stone J., Attokaran A., Farquharson M., Patel B., Gunning D., Baillie K., Adem S., Watson P., Tamai K., Sajinadiyasa G. K., Kanyawati D., Salgado M., Sassine A., Yudo B., McCaul S., Lee B., Lee S. M., Afek A., Iwashita Y., Fadlalmola H., Semedi B. P., Mansour N. 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A., Aliudin J., Alqahtani A. -R., Mohamed K., Mohamed A., Tan D., Villanueva J., Zaqout A., Kurtzman E., Ademi A., Dobrita A., El Aoudi K., Segura J., Giwangkancana G., Ohshimo S., Osatnik J., Joosten A., Torres A., Yang M., Motos A., Luna C., Arancibia F., Williams V., Noel A., Luque N., Fantini M., Garcia R. N. J., Alvarez E. C., Greti A., Ceccato A., Sanchez A., Vazquez A. L., Roche-Campo F., Franch-Llasat D., Tuazon D., Amato M., Cassimiro L., Pola F., Ribeiro F., Fonseca G., Dalton H., Desai M., Osborn E., Deeb H., Arcadipane A., Martucci G., Panarello G., Vitiello S., Bianco C., Occhipinti G., Rossetti M., Cuffaro R., Cho S. -M., Whitman G., El Sayed M., Mokhtar W., El-Shenawy E., Shimizu H., Moriyama N., Kim J. -B., Kitamura N., Gebauer J., Yokoyama T., Al-Fares A., Buabbas S., Alamad E., Alawadhi F., Alawadi K., Khalefa M. A., Al Ajeel N. A. A., Aly M. F., Al-Saleh A., Naanouh A., Elshourbgy A. M., Gad M. Y., ElRazaz R. M., Khadadah I., Almumin A. M., Altarakma H., Albannay H., Alsaleh M. K., Radwan M. S. A., Saadallah I. A., Tanaka H., Hashimoto S., Yamazaki M., Oh T. -H., Epler M., Forney C., Kruse L., Feister J., Williamson J., Grobengieser K., Gnall E., Golden S., Caroline M., Shapiro T., Karaj C., Thome L., Sher L., Vanderland M., Welch M., McDermott S., Brain M., Mineall S., Unwin M., Chen L., Trezise T., McKeon L., Kimura D., Brazzi L., Sales G., Montrucchio G., Ogston T., Nagpal D., Fischer K., Lorusso R., van Bussell B., De Piero M. E., Mariani S., Rangappa R., Shetty R. M., Rai P. S., Ganesan A., Esperatti M., Fuentes N. A., Gonzalez M. E., Carton E. G., Sen A., Palacios A., Rainey D., Samoukoviv G., Campisi J., Durham L., Neumann E., Seefeldt C., Falcucci O., Emmrich A., Guy J., Johns C., Potzner K., Zimmermann C., Espinal A., Buchtele N., Schwameis M., Korhnfehl A., Brock R., Staudinger T., Stecher S. -S., Barnikel M., Anton S., Pawlikowski A., Zaaqoq A., Galloway L. A., Merley C., Nichol A., Csete M., Quesada L., Saba I., Kasugai D., Hiraiwa H., Tanaka T., Marwali E., Purnama Y., Dewayanti S. R., Juzar D. A., Siagian D., Chen Y. -S., Ogino M., Nasa P., Matthew C., Majeed N. A., Ratsep I., Post A. -M., Sillaots P., Krund A., Lehiste M. -H., Lepik T., Manetta F., Mihelis E., Sarmiento I. C., Narasimhan M., Varrone M., Komats M., Garcia-Diaz J., Harmon C., Satyapriya S. V., Bhatt A., Mokadam N. A., Uribe A., Gonzalez A., Shi H., McKeown J., Pasek J., Fiorda J., Echeverria M., Moreno R., Zakhary B., Cavana M., Cucino A., Foti G., Giani M., Fumagalli B., Chiumello D., Castagna V., Dell'Amore A., Navalesi P., Shum H. -P., Vuysteke A., Usman A., Acker A., Smood B., Mergler B., Sertic F., Subramanian M., Sperry A., Rizer N., Burhan E., Rasmin M., Akmal E., Sitompul F., Lolong N., Naivedh B., Erickson S., Barrett P., Dean D., Daugherty J., Loforte A., Khan I., Quraishi M. A., DeSantis O., So D., Kandamby D., Mandei J. M., Natanael H., YudhaLantang E., Lantang A., Wijaya S. O., Jung A., Ng G., Ng W. Y., Ng P. Y., Fang S., Tabah A., Ratcliffe M., Duroux M., Alajeeli A., Tarhabat A., Adachi S., Nakao S., Blanco P., Prieto A., Sanchez J., Nicholson M., Butt W., Serratore A., Delzoppo C., Janin P., Yarad E., Totaro R., Coles J., Pujo B., Balk R., Vissing A., Kapania E., Hays J., Fox S., Yantosh G., Mishin P., Yuliarto S., Santoso K. H., Djajalaksana S., Fatoni A. Z., Fukuda M., Liu K., Pelosi P., Battaglini D., Jimenez J. F. M., Bastos D., Gaiao S., Rusmawatiningtyas D., Cho Y. -J., Lee S. H., Kawasaki T., Munshi L., Sakiyalak P., Nitayavardhana P., Elagili M. B., Salem T. A. A., Seitz T., Arora R., Kent D., Marino D., Parwar S., Cheng A., Miller J., Fujitani S., Shimizu N., Madhok J., Owyang C., Buscher H., Reynolds C., Maasikas O., AleksanBeljantsev, Mihnovits V., Akimoto T., Aizawa M., Horibe K., Onodera R., Hodgson C., Burrell A., Young M., George T., Shekar K., McGuinness N., Irvine L., Flynn B., Endo T., Sugiyama K., Shimizu K., Fan E., Exconde K., Ichiba S., Binnawara M., Lussier L., Lotz G., Malfertheiner M., Maier L., Dreier E., Kusumastuti N. P., McCloskey C., Dabaliz A. -A., Elshazly T. B., Smith J., Szuldrzynski K. S., Bielanski P., Wille K., Murthy S., Parhar K. K. S., Fiest K. M., Codan C., Shahid A., Fayed M., Evans T., Garcia R., Gutierrez A., Song T., Rose R., Bennett S., Richardson D., Peek G., Arora L., Rappapport K., Rudolph K., Sibenaller Z., Stout L., Walter A., Herr D., Vedadi N., Bartlett R., Thompson S., Hoffman J., Ying X., Williams B., Sanchez E., Akwani C., Kennedy R., Elhadi M., Griffee M., Mone M., Ciullo A., Kida Y., Roca R. F., Riera J. I., Contreras S., Alegre C., Kay C., Fischer I., Renner E., Taniguci H., Lee J., Plotkin D., Citarella B. W., Merson L., Hartley E., Lubis B., Ikeyama T., Alhamad A., Fathi M., Hadhoud M. M., Alhouri H., Mechi A., Alyasiri M. S., Elsaid M. Z. A., Shahla H., Bhaskar B., Jung J. -S., McGuinness S., Eastwood G., Marta S. R., Guarracino F., Gerle S., Coxon E., Claro B., Eleisawy M., Osama H., Loverde D., Patil N., Parrini V., McBride A., Negaard K., Ratsch A., Uribe J. D., Peris A., Sanders M., Emerson D., Kamal M., Faida H., Povoa P., Francis R., Cherif A., Joseph S., Di Nardo M., Heard M., Kyle K., Blackwell R. A., Ouyahia A., Biston P., Jeong H. W., Smith R., Prawira Y., Garcia A. H., Salterain N., Meyns B., Elnasser M., Moreno M., Walia R., Mehta A., Schweda A., Williams M., EmadAmkhatirah, Kim K. H., Assad A., Giraldo E., Karolak W., Balik M., Pocock E., Gajkowski E., Masafumi K., Barrett N., Takeyama Y., Park S., Amin F., Andriyani F. M., Sudakevych S., Schnur J., Vera M., Cornejo R., Schwarz P., Mardini A. C., de Paula T., Neto A. S., Villoldo A., Colafranceschi A. S., Iglesias A. U., Granjean J., Melro L. M. G., Romualdo G. F., Gaia D., Souza H., Galas F., Mendiluce R. M., Sosa A., Martinez I., Kurosawa H., Almoshantaf M. B., Salgado J., Hugi-Mayr B., Charbonneau E., Barzilai V. S., Monteiro V., de Souza R. R., Harper M., Siddig N., Suzuki H., Adams C., Brieva J., Khamees A., Graige F., Supriatna M., Nyale G., Eltatar F. S., Fatani J., Baeissa H., Masri A. A. L., Rabie A., Hui M. Y., Yamane M., Jung H., Margaret A. M., Nacpil N., Ruck K., Bakken R., Jara C., Felton T., Tharwat S., Berra L., Shah B., Chakraborty A., Cardona M., Capatos G., Akkanti B., Orija A., Jain H., Ito A., Muftah M., Housni B., Aldhalia A., Low S., Iihara K., Chavez J., Ramanathan K., Naidoo K., Seppelt I., VanDyk M., MacDonald S., Hafez W., McGregor R., Siebenaler T., Flynn H., Lofton K., Aokage T., Kvirkvelia B., Shigemitsu K., Moscatelli A., Fiorentino G., Baumgaertel M., Mba S. E., Assy J., Hutahaean A., Roush H., Sichting K. A., Alessandri F., Burns D., Alkhubouli T. H., Nasrallah A., Salt G., Garabedian C. P., Millar J., Sim M., Mattke A., McAuley D., Tadili J., Frenzel T., Bar-Lavie Y., Ortiz A. B., Stone J., Attokaran A., Farquharson M., Patel B., Gunning D., Baillie K., Adem S., Watson P., Tamai K., Sajinadiyasa G. K., Kanyawati D., Salgado M., Sassine A., Yudo B., McCaul S., Lee B., Lee S. M., Afek A., Iwashita Y., Fadlalmola H., Semedi B. P., Mansour N. M., Metiva J., Van Belle N., Martin-Loeches I., Al-Sadawi M., Kirakli C., Shimaa A. -T., Abdurraouf A., Ivatt L., Moharam S., Woon C. Y., Kang H. M., Smith T., James E., Al-Rawas N., Almjersah A., Iwasaki Y., Ashour H., Embarek H., King-Chung K. C., Gudzenko V., Taccone F., Perdhana F., Lamarche Y., Ribeiro J. M., Bradic N., Van den Bossche K., Lansink O., Singh G., Debeuckelaere G., Stelfox H. T., Yi C., Elia J., Tribble T., Shankar S., Padmanabhan R., Hallinan B., Paoletti L., Leyva Y., Fykuda T., Badulak J., Koch J., Janowaik L., Hackman A., Hernandez D., Osofsky J., Donadello K., Lawang A., Fine J., Davidson B., Vazquez A. O. R., and Abdehaleem I.
- Abstract
Following publication of the original article [1], the authors identified that the collaborating authors part of the collaborating author group CCCC Consortium was missing. The collaborating author group is available and included as Additional file 1 in this article.
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- 2023
9. Modelling the spectral energy distribution of galaxies: introducing the artificial neural network
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Silva, L., Schurer, A., Granato, G. L., Almeida, C., Baugh, C. M., Frenk, C. S., Lacey, C. G., Paoletti, L., Petrella, A., and Selvestrel, D.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
The spectral energy distribution of galaxies is a complex function of the star formation history and geometrical arrangement of stars and gas in galaxies. The computation of the radiative transfer of stellar radiation through the dust distribution is time-consuming. This aspect becomes unacceptable in particular when dealing with the predictions by semi-analytical galaxy formation models populating cosmological volumes, to be then compared with multi-wavelength surveys. Mainly for this aim, we have implemented an artificial neural network algorithm into the spectro-photometric and radiative transfer code GRASIL in order to compute the spectral energy distribution of galaxies in a short computing time. This allows to avoid the adoption of empirical templates that may have nothing to do with the mock galaxies output by models. The ANN has been implemented to compute the dust emission spectrum (the bottleneck of the computation), and separately for the star-forming molecular clouds and the diffuse dust (due to their different properties and dependencies). We have defined the input neurons effectively determining their emission, which means this implementation has a general applicability and is not linked to a particular galaxy formation model. We have trained the net for the disc and spherical geometries, and tested its performance to reproduce the SED of disc and starburst galaxies, as well as for a semi-analytical model for spheroidal galaxies. We have checked that for this model both the SEDs and the galaxy counts in the Herschel bands obtained with the ANN approximation are almost superimposed to the same quantities obtained with the full GRASIL. We conclude that this method appears robust and advantageous, and will present the application to a more complex SAM in another paper., Comment: 16 pages, 14 figures, MNRAS, Accepted 2010 August 22
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- 2010
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10. Oropharyngeal swallow physiology and swallowing-related quality of life in underweight patients with concomitant advanced chronic obstructive pulmonary disease
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Garand KL, Strange C, Paoletti L, Hopkins-Rossabi T, and Martin-Harris B
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COPD ,swallowing impairment ,MBSImP ,dysphagia ,and underweight ,Diseases of the respiratory system ,RC705-779 - Abstract
Kendrea L Garand,1 Charlie Strange,2 Luca Paoletti,2 Theresa Hopkins-Rossabi,3 Bonnie Martin-Harris3 1Department of Speech Pathology and Audiology, College of Allied Health Professions, University of South Alabama, Mobile, AL 36688, USA; 2Division of Pulmonary, Critical Care, and Sleep Medicine, College of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA; 3Department of Communication Sciences and Disorders, School of Communication, Northwestern University, Evanston, IL 60208, USA Background: Swallowing impairment (dysphagia) has been associated with COPD and may contribute to exacerbations of this chronic and progressive disease. Further, risk of mortality increases with concomitant presence of cachexia in the COPD population. The purpose of this prospective study was to depict oropharyngeal swallowing physiology in underweight patients with stable but advanced-stage COPD. Patients and methods: Ten underweight patients with stable but advanced COPD underwent a modified barium swallow study. Analysis of oropharyngeal swallowing function was completed using the standardized Modified Barium Swallow Impairment Profile and the Penetration–Aspiration Scale. Scores from the Dysphagia Handicap Index and 10-item Eating Assessment Tool were collected to assess patient perception of swallowing difficulty. Findings were compared to age- and sex-matched healthy controls. Results: Significantly higher MBSImP oral total scores (P=0.007) were observed in COPD patients compared to matched controls, but no difference was observed in pharyngeal total scores (P=0.105). Patients with COPD had significantly higher maximum PAS scores compared with controls (P=0.030). There was no significant difference in EAT-10 or DHI scores between patients with COPD and controls (P=0.41 and P=0.08, respectively). Conclusion: Underweight patients with severe but stable COPD present with dysphagia that may not be recognized by the patient. Further investigation is needed to elucidate the interaction between the respiratory–swallowing systems, how muscular weakness may contribute to swallowing impairment, and responsiveness to swallowing treatment. Keywords: COPD, swallowing impairment, MBSImP, dysphagia, underweight
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- 2018
11. BEaTriX, the new facility to measure the modular X-ray optics of the ATHENA telescope with an expanded and parallel X-ray beam
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Basso, S., primary, Salmaso, B., additional, Spiga, D., additional, Ghigo, M., additional, Vecchi, G., additional, Sironi, G., additional, Cotroneo, V., additional, Conconi, P., additional, Redaelli, E., additional, Bianco, A., additional, Pareschi, G., additional, Tagliaferri, G., additional, Sisana, D., additional, Pelliciari, C., additional, Fiorini, M., additional, Incorvaia, S., additional, Uslenghi, M., additional, Paoletti, L., additional, Ferrari, C., additional, Lolli, R., additional, Zappettini, A., additional, Sanchez del Rio, M., additional, Parodi, G., additional, Burwitz, V., additional, Rukdee, S., additional, Hartner, G., additional, Müller, T., additional, Schmidt, T., additional, Langmeier, A., additional, Della Monica Ferreira, D., additional, Massahi, S., additional, Gellert, N. C., additional, Christensen, F., additional, Bavdaz, M., additional, Ferreira, I., additional, Collon, M., additional, Vacanti, G., additional, and Barrière, N. M., additional
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- 2023
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12. Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis
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Li Bassi, G, Gibbons, K, Suen, J, Dalton, H, White, N, Corley, A, Shrapnel, S, Hinton, S, Forsyth, S, Laffey, J, Fan, E, Fanning, J, Panigada, M, Bartlett, R, Brodie, D, Burrell, A, Chiumello, D, Elhazmi, A, Esperatti, M, Grasselli, G, Hodgson, C, Ichiba, S, Luna, C, Marwali, E, Merson, L, Murthy, S, Nichol, A, Ogino, M, Pelosi, P, Torres, A, Ng, P, Fraser, J, Al-Dabbous, T, Alfoudri, H, Shamsah, M, Elapavaluru, S, Berg, A, Horn, C, Mayasi, Y, Schroll, S, Meyer, D, Velazco, J, Ploskanych, L, Fikes, W, Bagewadi, R, Dao, M, White, H, Ehlers, A, Shalabi-McGuire, M, Witt, T, Grazioli, L, Lorini, L, Grandin, E, Nunez, J, Reyes, T, Obriain, D, Hunter, S, Ramanan, M, Affleck, J, Veerendra, H, Rai, S, Russell-Brown, J, Nourse, M, Joseph, M, Mitchell, B, Tenzer, M, Abe, R, Cho, H, Jeong, I, Rahman, N, Kakar, V, Brozzi, N, Mehkri, O, Krishnan, S, Duggal, A, Houltham, S, Graf, J, Diaz, R, Orrego, R, Delgado, C, Gonzalez, J, Sanchez, M, Piagnerelli, M, Sarrazin, J, Zabert, A, Espinosa, L, Delgado, P, Delgado, V, Rincon, D, Yanten, A, Duque, M, Al-Hudaib, A, Callahan, M, Taufik, M, Wardoyo, E, Gunawan, M, Trisnaningrum, N, Irawany, V, Rayhan, M, Pesenti, A, Zanella, A, Leone, M, Coppola, S, Colombo, S, Antonelli, M, Carelli, S, Grieco, D, Asaki, M, Hoshino, K, Salazar, L, Duarte, L, Mcnicholas, B, Cosgrave, D, Mccaffrey, J, Bone, A, Hakeem, Y, Winearls, J, Tallott, M, Thomson, D, Arnold-Day, C, Cupido, J, Miller, M, Seymore, L, van Straaten, D, Hssain, A, Aliudin, J, Alqahtani, A, Mohamed, K, Mohamed, A, Tan, D, Villanueva, J, Zaqout, A, Kurtzman, E, Ademi, A, Dobrita, A, El Aoudi, K, Segura, J, Giwangkancana, G, Ohshimo, S, Hitoshi, S, Osatnik, J, Joosten, A, Yang, M, Motos, A, Arancibia, F, Williams, V, Noel, A, Luque, N, Trung, T, Yacoub, S, Fantini, M, Garcia, R, Alvarez, E, Greti, A, Ceccato, A, Sanchez, A, Vazquez, A, Roche-Campo, F, Franch-Llasat, D, Tuazon, D, Amato, M, Cassimiro, L, Pola, F, Ribeiro, F, Fonseca, G, Desai, M, Osborn, E, Deeb, H, Arcadipane, A, Martucci, G, Panarello, G, Vitiello, C, Bianco, C, Occhipinti, G, Rossetti, M, Cuffaro, R, Cho, S, Shimizu, H, Moriyama, N, Kim, J, Kitamura, N, Gebauer, J, Yokoyama, T, Al-Fares, A, Buabbas, S, Alamad, E, Alawadhi, F, Alawadi, K, Tanaka, H, Hashimoto, S, Yamazaki, M, Oh, T, Epler, M, Forney, C, Kruse, L, Feister, J, Williamson, J, Grobengieser, K, Gnall, E, Golden, S, Caroline, M, Shapiro, T, Karaj, C, Thome, L, Sher, L, Vanderland, M, Welch, M, Mcdermott, S, Brain, M, Mineall, S, Kimura, D, Brazzi, L, Sales, G, Ogston, T, Nagpal, D, Fischer, K, Lorusso, R, Rangappa, R, Appu, A, Carton, E, Sen, A, Palacios, A, Rainey, D, Samoukoviv, G, Campisi, J, Durham, L, Neumann, E, Seefeldt, C, Falcucci, O, Emmrich, A, Guy, J, Johns, C, Potzner, K, Zimmermann, C, Espinal, A, Buchtele, N, Schwameis, M, Stecher, S, Singh, D, Barnikel, M, Arenz, L, Zaaqoq, A, Galloway, L, Merley, C, Csete, M, Quesada, L, Saba, I, Kasugai, D, Hiraiwa, H, Tanaka, T, Purnama, Y, Dewayanti, S, Ardiyan, Juzar, D, Siagian, D, Chen, Y, Ratsep, I, Oigus, G, Erikson, K, Post, A, Enneveer, L, Sillaots, P, Manetta, F, Mihelis, E, Sarmiento, I, Narasimhan, M, Varrone, M, Komats, M, Garcia-Diaz, J, Harmon, C, Satyapriya, S, Bhatt, A, Mokadam, N, Uribe, A, Gonzalez, A, Shi, H, Mckeown, J, Pasek, J, Fiorda, J, Echeverria, M, Moreno, R, Zakhary, B, Cavana, M, Cucino, A, Foti, G, Giani, M, Russotto, V, Castagna, V, Dellamore, A, Navalesi, P, Shum, H, Vuysteke, A, Usman, A, Acker, A, Smood, B, Mergler, B, Sertic, F, Subramanian, M, Sperry, A, Rizer, N, Burhan, E, Rasmin, M, Akmal, E, Sitompul, F, Lolong, N, Naivedh, B, Erickson, S, Barrett, P, Dean, D, Daugherty, J, Loforte, A, Khan, I, Abraar Quraishi, M, Desantis, O, So, D, Kandamby, D, Mandei, J, Natanael, H, Yudhalantang, E, Lantang, A, Wijaya, S, Jung, A, Ng, G, Ng, W, Fang, S, Tabah, A, Ratcliffe, M, Duroux, M, Adachi, S, Nakao, S, Blanco, P, Prieto, A, Sanchez, J, Nicholson, M, Butt, W, Serratore, A, Delzoppo, C, Janin, P, Yarad, E, Totaro, R, Coles, J, Pujo, B, Balk, R, Vissing, A, Kapania, E, Hays, J, Fox, S, Yantosh, G, Mishin, P, Yuliarto, S, Hari Santoso, K, Djajalaksana, S, Fatoni, A, Fukuda, M, Liu, K, Battaglini, D, Jimenez, J, Bastos, D, Gaiao, S, Rusmawatiningtyas, D, Buchner, J, Cho, Y, Lee, S, Kawasaki, T, Munshi, L, Sakiyalak, P, Nitayavardhana, P, Seitz, T, Arora, R, Kent, D, Marino, D, Parwar, S, Cheng, A, Miller, J, Fujitani, S, Shimizu, N, Madhok, J, Owyang, C, Buscher, H, Reynolds, C, Maasikas, O, Beljantsev, A, Mihnovits, V, Akimoto, T, Aizawa, M, Horibe, K, Onodera, R, Young, M, George, T, Shekar, K, Mcguinness, N, Irvine, L, Flynn, B, Endo, T, Sugiyama, K, Shimizu, K, Exconde, K, Lussier, L, Lotz, G, Malfertheiner, M, Maier, L, Dreier, E, Kusumastuti, N, Mccloskey, C, Dabaliz, A, Elshazly, T, Smith, J, Szuldrzynski, K, Bielanski, P, Wille, K, Parhar, K, Fiest, K, Codan, C, Shahid, A, Fayed, M, Evans, T, Gutierrez, A, Song, T, Rose, R, Bennett, S, Richardson, D, Peek, G, Arora, L, Rappapport, K, Rudolph, K, Sibenaller, Z, Stout, L, Walter, A, Herr, D, Vedadi, N, Thompson, S, Sindt, L, Rajnic, S, Ewald, C, Hoffman, J, Ying, X, Kennedy, R, Griffee, M, Ciullo, A, Kida, Y, Roca, R, Riera, J, Contreras, S, Alegre, C, Kay, C, Fischer, I, Renner, E, Taniguci, H, Bassi, G, Barnett, A, Pearse, I, Abbate, G, Hassan, H, Heinsar, S, Karnik, V, Ki, K, Oneill, H, Obonyo, N, Pimenta, L, Reid, J, Sato, K, Vuorinen, A, Wildi, K, Wood, E, Yerkovich, S, Lee, J, Plotkin, D, Citarella, B, Hartley, E, Lubis, B, Ikeyama, T, Bhaskar, B, Jung, J, Mcguinness, S, Eastwood, G, Marta, S, Guarracino, F, Gerle, S, Coxon, E, Claro, B, Loverde, D, Patil, N, Parrini, V, Mcbride, A, Negaard, K, Ratsch, A, Abdelaziz, A, Uribe, J, Peris, A, Sanders, M, Emerson, D, Kamal, M, Povoa, P, Francis, R, Cherif, A, Joseph, S, Di Nardo, M, Heard, M, Kyle, K, Blackwell, R, Biston, P, Jeong, H, Smith, R, Prawira, Y, Montrucchio, G, Garcia, A, Salterain, N, Meyns, B, Moreno, M, Walia, R, Mehta, A, Schweda, A, Supriatna, M, Kirakli, C, Williams, M, Kim, K, 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G., Espinosa L., Delgado P., Delgado V., Rincon D. F. B., Yanten A. M. M., Duque M. B., Al-Hudaib A., Callahan M., Taufik M. A., Wardoyo E. Y., Gunawan M., Trisnaningrum N. S., Irawany V., Rayhan M., Pesenti A., Zanella A., Leone M., Coppola S., Colombo S., Antonelli M., Carelli S., Grieco D. L., Asaki M., Hoshino K., Salazar L., Duarte L., McNicholas B., Cosgrave D., McCaffrey J., Bone A., Hakeem Y., Winearls J., Tallott M., Thomson D., Arnold-Day C., Cupido J., Miller M., Seymore L., van Straaten D., Hssain A. A., Aliudin J., Alqahtani A. -R., Mohamed K., Mohamed A., Tan D., Villanueva J., Zaqout A., Kurtzman E., Ademi A., Dobrita A., El Aoudi K., Segura J., Giwangkancana G., Ohshimo S., Hitoshi S., Osatnik J., Joosten A., Yang M., Motos A., Arancibia F., Williams V., Noel A., Luque N., Trung T. H., Yacoub S., Fantini M., Garcia R. N. J., Alvarez E. C., Greti A., Ceccato A., Sanchez A., Vazquez A. L., Roche-Campo F., Franch-Llasat D., Tuazon D., Amato M., Cassimiro L., Pola F., Ribeiro F., Fonseca G., Dalton H., Desai M., Osborn E., Deeb H., Arcadipane A., Martucci G., Panarello G., Vitiello C., Bianco C., Occhipinti G., Rossetti M., Cuffaro R., Cho S. -M., Shimizu H., Moriyama N., Kim J. -B., Kitamura N., Gebauer J., Yokoyama T., Al-Fares A., Buabbas S., Alamad E., Alawadhi F., Alawadi K., Tanaka H., Hashimoto S., Yamazaki M., Oh T. -H., Epler M., Forney C., Kruse L., Feister J., Williamson J., Grobengieser K., Gnall E., Golden S., Caroline M., Shapiro T., Karaj C., Thome L., Sher L., Vanderland M., Welch M., McDermott S., Brain M., Mineall S., Kimura D., Brazzi L., Sales G., Ogston T., Nagpal D., Fischer K., Lorusso R., Rangappa R., Appu A., Carton E. G., Sen A., Palacios A., Rainey D., Samoukoviv G., Campisi J., Durham L., Neumann E., Seefeldt C., Falcucci O., Emmrich A., Guy J., Johns C., Potzner K., Zimmermann C., Espinal A., Buchtele N., Schwameis M., Stecher S. -S., Singh D., Barnikel M., Arenz L., Zaaqoq A., Galloway L. A., Merley C., Csete M., Quesada L., Saba I., Kasugai D., Hiraiwa H., Tanaka T., Purnama Y., Dewayanti S. R., Juzar D. A., Siagian D., Chen Y. -S., Ratsep I., Oigus G., Erikson K., Post A. -M., Enneveer L., Sillaots P., Manetta F., Mihelis E., Sarmiento I. C., Narasimhan M., Varrone M., Komats M., Garcia-Diaz J., Harmon C., Satyapriya S. V., Bhatt A., Mokadam N. 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Baumgaertel, M, Mba, S, Assy, J, Hutahaean, A, Roush, H, Sichting, K, Alessandri, F, Burns, D, Salt, G, Garabedian, C, Millar, J, Sim, M, Mattke, A, Mcauley, D, Tadili, J, Frenzel, T, Bar-Lavie, Y, Ortiz, A, Stone, J, Attokaran, A, Farquharson, M, Patel, B, Gunning, D, Baillie, K, Watson, P, Tamai, K, Sajinadiyasa, G, Kanyawati, D, Salgado, M, Sassine, A, Yudo, B, Mccaul, S, Lee, B, Afek, A, Iwashita, Y, Semedi, B, Metiva, J, Van Belle, N, Martin-Loeches, I, Ivatt, L, Woon, C, Kang, H, Smith, T, James, E, Al-Rawas, N, Iwasaki, Y, King-Chung, K, Gudzenko, V, Hugi-Mayr, B, Taccone, F, Perdhana, F, Lamarche, Y, Ribeiro, J, Bradic, N, Van den Bossche, K, Lansink, O, Singh, G, Debeuckelaere, G, Stelfox, H, Yi, C, Elia, J, Tribble, T, Shankar, S, Padmanabhan, R, Hallinan, B, Paoletti, L, Leyva, Y, Fykuda, T, Badulak, J, Koch, J, Hackman, A, Janowaik, L, Hernandez, D, Osofsky, J, Donadello, K, Lawang, A, Fine, J, Davidson, B, Li Bassi G., Gibbons K., Suen J. Y., Dalton H. J., White N., Corley A., Shrapnel S., Hinton S., Forsyth S., Laffey J. G., Fan E., Fanning J. P., Panigada M., Bartlett R., Brodie D., Burrell A., Chiumello D., Elhazmi A., Esperatti M., Grasselli G., Hodgson C., Ichiba S., Luna C., Marwali E., Merson L., Murthy S., Nichol A., Ogino M., Pelosi P., Torres A., Ng P. Y., Fraser J. F., Al-Dabbous T., Alfoudri H., Shamsah M., Elapavaluru S., Berg A., Horn C., Mayasi Y., Schroll S., Meyer D., Velazco J., Ploskanych L., Fikes W., Bagewadi R., Dao M., White H., Ehlers A., Shalabi-McGuire M., Witt T., Grazioli L., Lorini L., Grandin E. W., Nunez J., Reyes T., OBriain D., Hunter S., Ramanan M., Affleck J., Veerendra H. H., Rai S., Russell-Brown J., Nourse M., Joseph M., Mitchell B., Tenzer M., Abe R., Cho H. J., Jeong I. S., Rahman N., Kakar V., Brozzi N., Mehkri O., Krishnan S., Duggal A., Houltham S., Graf J., Diaz R., Orrego R., Delgado C., Gonzalez J., Sanchez M. S., Piagnerelli M., Sarrazin J. V., Zabert A. /P. G., Espinosa L., Delgado P., Delgado V., Rincon D. F. B., Yanten A. M. M., Duque M. B., Al-Hudaib A., Callahan M., Taufik M. A., Wardoyo E. Y., Gunawan M., Trisnaningrum N. S., Irawany V., Rayhan M., Pesenti A., Zanella A., Leone M., Coppola S., Colombo S., Antonelli M., Carelli S., Grieco D. L., Asaki M., Hoshino K., Salazar L., Duarte L., McNicholas B., Cosgrave D., McCaffrey J., Bone A., Hakeem Y., Winearls J., Tallott M., Thomson D., Arnold-Day C., Cupido J., Miller M., Seymore L., van Straaten D., Hssain A. A., Aliudin J., Alqahtani A. -R., Mohamed K., Mohamed A., Tan D., Villanueva J., Zaqout A., Kurtzman E., Ademi A., Dobrita A., El Aoudi K., Segura J., Giwangkancana G., Ohshimo S., Hitoshi S., Osatnik J., Joosten A., Yang M., Motos A., Arancibia F., Williams V., Noel A., Luque N., Trung T. H., Yacoub S., Fantini M., Garcia R. N. J., Alvarez E. C., Greti A., Ceccato A., Sanchez A., Vazquez A. L., Roche-Campo F., Franch-Llasat D., Tuazon D., Amato M., Cassimiro L., Pola F., Ribeiro F., Fonseca G., Dalton H., Desai M., Osborn E., Deeb H., Arcadipane A., Martucci G., Panarello G., Vitiello C., Bianco C., Occhipinti G., Rossetti M., Cuffaro R., Cho S. -M., Shimizu H., Moriyama N., Kim J. -B., Kitamura N., Gebauer J., Yokoyama T., Al-Fares A., Buabbas S., Alamad E., Alawadhi F., Alawadi K., Tanaka H., Hashimoto S., Yamazaki M., Oh T. -H., Epler M., Forney C., Kruse L., Feister J., Williamson J., Grobengieser K., Gnall E., Golden S., Caroline M., Shapiro T., Karaj C., Thome L., Sher L., Vanderland M., Welch M., McDermott S., Brain M., Mineall S., Kimura D., Brazzi L., Sales G., Ogston T., Nagpal D., Fischer K., Lorusso R., Rangappa R., Appu A., Carton E. G., Sen A., Palacios A., Rainey D., Samoukoviv G., Campisi J., Durham L., Neumann E., Seefeldt C., Falcucci O., Emmrich A., Guy J., Johns C., Potzner K., Zimmermann C., Espinal A., Buchtele N., Schwameis M., Stecher S. -S., Singh D., Barnikel M., Arenz L., Zaaqoq A., Galloway L. A., Merley C., Csete M., Quesada L., Saba I., Kasugai D., Hiraiwa H., Tanaka T., Purnama Y., Dewayanti S. R., Juzar D. A., Siagian D., Chen Y. -S., Ratsep I., Oigus G., Erikson K., Post A. -M., Enneveer L., Sillaots P., Manetta F., Mihelis E., Sarmiento I. C., Narasimhan M., Varrone M., Komats M., Garcia-Diaz J., Harmon C., Satyapriya S. V., Bhatt A., Mokadam N. A., Uribe A., Gonzalez A., Shi H., McKeown J., Pasek J., Fiorda J., Echeverria M., Moreno R., Zakhary B., Cavana M., Cucino A., Foti G., Giani M., Russotto V., Castagna V., DellAmore A., Navalesi P., Shum H. -P., Vuysteke A., Usman A., Acker A., Smood B., Mergler B., Sertic F., Subramanian M., Sperry A., Rizer N., Burhan E., Rasmin M., Akmal E., Sitompul F., Lolong N., Naivedh B., Erickson S., Barrett P., Dean D., Daugherty J., Loforte A., Khan I., Abraar Quraishi M., DeSantis O., So D., Kandamby D., Mandei J. M., Natanael H., YudhaLantang E., Lantang A., Wijaya S. O., Jung A., Ng G., Ng W. Y., Fang S., Tabah A., Ratcliffe M., Duroux M., Adachi S., Nakao S., Blanco P., Prieto A., Sanchez J., Nicholson M., Butt W., Serratore A., Delzoppo C., Janin P., Yarad E., Totaro R., Coles J., Pujo B., Balk R., Vissing A., Kapania E., Hays J., Fox S., Yantosh G., Mishin P., Yuliarto S., Hari Santoso K., Djajalaksana S., Fatoni A. Z., Fukuda M., Liu K., Battaglini D., Jimenez J. F. M., Bastos D., Gaiao S., Rusmawatiningtyas D., Buchner J., Cho Y. -J., Lee S. H., Kawasaki T., Munshi L., Sakiyalak P., Nitayavardhana P., Seitz T., Arora R., Kent D., Marino D., Parwar S., Cheng A., Miller J., Fujitani S., Shimizu N., Madhok J., Owyang C., Buscher H., Reynolds C., Maasikas O., Beljantsev A., Mihnovits V., Akimoto T., Aizawa M., Horibe K., Onodera R., Young M., George T., Shekar K., McGuinness N., Irvine L., Flynn B., Endo T., Sugiyama K., Shimizu K., Exconde K., Lussier L., Lotz G., Malfertheiner M., Maier L., Dreier E., Kusumastuti N. P., McCloskey C., Dabaliz A. -A., Elshazly T. B., Smith J., Szuldrzynski K. S., Bielanski P., Wille K., Parhar K. K. S., Fiest K. M., Codan C., Shahid A., Fayed M., Evans T., Garcia R., Gutierrez A., Song T., Rose R., Bennett S., Richardson D., Peek G., Arora L., Rappapport K., Rudolph K., Sibenaller Z., Stout L., Walter A., Herr D., Vedadi N., Thompson S., Sindt L., Rajnic S., Ewald C., Hoffman J., Ying X., Kennedy R., Griffee M., Ciullo A., Kida Y., Roca R. F., Riera J. I., Contreras S., Alegre C., Kay C., Fischer I., Renner E., Taniguci H., Bassi G. L., Suen J., Barnett A., Pearse I., Abbate G., Hassan H., Heinsar S., Karnik V. A., Ki K., ONeill H. F., Obonyo N., Pimenta L. P., Reid J. D., Sato K., Vuorinen A., Wildi K. S., Wood E. S., Yerkovich S., Lee J., Plotkin D., Citarella B. W., Hartley E., Lubis B., Ikeyama T., Bhaskar B., Jung J. -S., McGuinness S., Eastwood G., Marta S. R., Guarracino F., Gerle S., Coxon E., Claro B., Loverde D., Patil N., Parrini V., McBride A., Negaard K., Ratsch A., Abdelaziz A., Uribe J. D., Peris A., Sanders M., Emerson D., Kamal M., Povoa P., Francis R., Cherif A., Joseph S., Di Nardo M., Heard M., Kyle K., Blackwell R. A., Biston P., Jeong H. W., Smith R., Prawira Y., Montrucchio G., Garcia A. H., Salterain N., Meyns B., Moreno M., Walia R., Mehta A., Schweda A., Supriatna M., Kirakli C., Williams M., Kim K. H., Assad A., Giraldo E., Karolak W., Balik M., Pocock E., Gajkowski E., Masafumi K., Barrett N., Takeyama Y., Park S., Amin F., Andriyani F. M., Sudakevych S., Vera M., Cornejo R., Schwarz P., Mardini A. C., de Paula T., Neto A. S., Villoldo A., Colafranceschi A. S., Iglesias A. U., Granjean J., Melro L. M. G., Romualdo G. F., Gaia D., Souza H., Galas F., Mendiluce R. M., Sosa A., Martinez I., Kurosawa H., Salgado J., Hugi-MayrCharbonneau B. E., Barzilai V. S., Monteiro V., de Souza R. R., Harper M., Suzuki H., Adams C., Brieva J., Nyale G., Eltatar F. S., Fatani J., Baeissa H., Masri A. A., Rabie A., Hui M. Y., Yamane M., Jung H., Margaret A. M., Nacpil N., Ruck K., Bakken R., Jara C., Felton T., Berra L., Shah B., Chakraborty A., Cardona M., Capatos G., Akkanti B., Orija A., Jain H., Ito A., Housni B., Low S., Iihara K., Chavez J., Ramanathan K., Zabert G., Naidoo K., Seppelt I., VanDyk M., MacDonald S., McGregor R., Siebenaler T., Flynn H., Lofton K., Aokage T., Shigemitsu K., Moscatelli A., Fiorentino G., Baumgaertel M., Mba S. E., Assy J., Hutahaean A., Roush H., Sichting K. A., Alessandri F., Burns D., Salt G., Garabedian C. P., Millar J., Sim M., Mattke A., McAuley D., Tadili J., Frenzel T., Bar-Lavie Y., Ortiz A. B., Stone J., Attokaran A., Farquharson M., Patel B., Gunning D., Baillie K., Watson P., Tamai K., Sajinadiyasa G. K., Kanyawati D., Salgado M., Sassine A., Yudo B., McCaul S., Lee B., Lee S. M., Afek A., Iwashita Y., Semedi B. P., Metiva J., Van Belle N., Martin-Loeches I., Ivatt L., Woon C. Y., Kang H. M., Smith T., James E., Al-Rawas N., Iwasaki Y., King-Chung K. C., Gudzenko V., Hugi-Mayr B., Taccone F., Perdhana F., Lamarche Y., Ribeiro J. M., Bradic N., Van den Bossche K., Lansink O., Singh G., Debeuckelaere G., Stelfox H. T., Yi C., Elia J., Tribble T., Shankar S., Padmanabhan R., Hallinan B., Paoletti L., Leyva Y., Fykuda T., Badulak J., Koch J., Hackman A., Janowaik L., Hernandez D., Osofsky J., Donadello K., Lawang A., Fine J., Davidson B., and Vazquez A. O. R.
- Abstract
Background: The role of neuromuscular blocking agents (NMBAs) in coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS) is not fully elucidated. Therefore, we aimed to investigate in COVID-19 patients with moderate-to-severe ARDS the impact of early use of NMBAs on 90-day mortality, through propensity score (PS) matching analysis. Methods: We analyzed a convenience sample of patients with COVID-19 and moderate-to-severe ARDS, admitted to 244 intensive care units within the COVID-19 Critical Care Consortium, from February 1, 2020, through October 31, 2021. Patients undergoing at least 2 days and up to 3 consecutive days of NMBAs (NMBA treatment), within 48 h from commencement of IMV were compared with subjects who did not receive NMBAs or only upon commencement of IMV (control). The primary objective in the PS-matched cohort was comparison between groups in 90-day in-hospital mortality, assessed through Cox proportional hazard modeling. Secondary objectives were comparisons in the numbers of ventilator-free days (VFD) between day 1 and day 28 and between day 1 and 90 through competing risk regression. Results: Data from 1953 patients were included. After propensity score matching, 210 cases from each group were well matched. In the PS-matched cohort, mean (± SD) age was 60.3 ± 13.2 years and 296 (70.5%) were male and the most common comorbidities were hypertension (56.9%), obesity (41.1%), and diabetes (30.0%). The unadjusted hazard ratio (HR) for death at 90 days in the NMBA treatment vs control group was 1.12 (95% CI 0.79, 1.59, p = 0.534). After adjustment for smoking habit and critical therapeutic covariates, the HR was 1.07 (95% CI 0.72, 1.61, p = 0.729). At 28 days, VFD were 16 (IQR 0–25) and 25 (IQR 7–26) in the NMBA treatment and control groups, respectively (sub-hazard ratio 0.82, 95% CI 0.67, 1.00, p = 0.055). At 90 days, VFD were 77 (IQR 0–87) and 87 (IQR 0–88) (sub-hazard ratio 0.86 (95% CI 0.69, 1.07; p =
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- 2022
13. PO-2029 Autoplanning tangential IMRT technique for DIBH breast radiotherapy: a robustness evaluation.
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Gnerucci, A., primary, Esposito, M., additional, Ghirelli, A., additional, Pini, S., additional, Paoletti, L., additional, Barca, R., additional, Fondelli, S., additional, Alpi, P., additional, Grilli, B., additional, Rossi, F., additional, Scoccianti, S., additional, and Russo, S., additional
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- 2023
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14. OC-0910 Immunogenicity after two/three doses of mRNA vaccine in cancer patients treated with radiotherapy
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Scoccianti, S., primary, Delli Paoli, C., additional, Infantino, M., additional, Paoletti, L., additional, Caini, S., additional, Meacci, F., additional, Russo, S., additional, Esposito, M., additional, Fondelli, S., additional, Grilli Leonulli, B., additional, Grossi, V., additional, Barca, R., additional, Alpi, P., additional, Furlan, F., additional, Perna, M., additional, Pino, M.S., additional, Martella, F., additional, Manfredi, M., additional, Stefanacci, M., additional, Bassetti, A., additional, Casprini, P., additional, and Fioretto, L., additional
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- 2023
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15. PO-1736 The role of in vivo dosimetry in the continuous quality improvement of lung stereotactic treatments
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Esposito, M., primary, Mancosu, P., additional, Bruschi, A., additional, Ghirelli, A., additional, Pini, S., additional, Alpi, P., additional, Barca, R., additional, Delli Paoli, C., additional, Meacci, F., additional, Grilli Leonulli, B., additional, Fondelli, S., additional, Paoletti, L., additional, Scoccianti, S., additional, and Russo, S., additional
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- 2023
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16. (920) Elective Cardiopulmonary Bypass for Lung Transplantation: Is It Safer Than We Think
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Blanding, W., primary, Hill, M., additional, Hashmi, Z., additional, Whelan, T., additional, Paoletti, L., additional, Engelhardt, K., additional, and Gibney, B., additional
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- 2023
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17. BEaTriX, the new facility to measure the modular X-ray optics of the ATHENA telescope with an expanded and parallel X-ray beam
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Minoglou, Kyriaki, Karafolas, Nikos, Cugny, Bruno, Basso, S., Salmaso, B., Spiga, D., Ghigo, M., Vecchi, G., Sironi, G., Cotroneo, V., Conconi, P., Redaelli, E., Bianco, A., Pareschi, G., Tagliaferri, G., Sisana, D., Pelliciari, C., Fiorini, M., Incorvaia, S., Uslenghi, M., Paoletti, L., Ferrari, C., Lolli, R., Zappettini, A., del Rio, M. Sanchez, Parodi, G., Burwitz, V., Rukdee, S., Hartner, G., Müller, T., Schmidt, T., Langmeier, A., Della Monica Ferreira, D., Massahi, S., Gellert, N. C., Christensen, F., Bavdaz, M., Ferreira, I., Minoglou, Kyriaki, Karafolas, Nikos, Cugny, Bruno, Basso, S., Salmaso, B., Spiga, D., Ghigo, M., Vecchi, G., Sironi, G., Cotroneo, V., Conconi, P., Redaelli, E., Bianco, A., Pareschi, G., Tagliaferri, G., Sisana, D., Pelliciari, C., Fiorini, M., Incorvaia, S., Uslenghi, M., Paoletti, L., Ferrari, C., Lolli, R., Zappettini, A., del Rio, M. Sanchez, Parodi, G., Burwitz, V., Rukdee, S., Hartner, G., Müller, T., Schmidt, T., Langmeier, A., Della Monica Ferreira, D., Massahi, S., Gellert, N. C., Christensen, F., Bavdaz, M., and Ferreira, I.
- Abstract
BEaTriX (Beam Expander Testing X-ray facility) is the new facility available at the INAF-Osservatorio Astronomico Brera (Merate, Italy) for the calibration of X-ray optics. Specifically designed to measure the point spread function (PSF) and the effective area (EA) of the mirror modules (MM) of the ATHENA X-ray telescope at their production rate, BEaTriX gives the unique possibility to test the optics with a source that approximate an astronomical source, i.e. with a large, parallel X-ray beam (170 × 60 mm2) that fully covers the entrance pupil of the MM. For a fast and precise testing, BEaTriX is a compact facility (9 × 18 m2) with fast vacuum pump-down (to 10-6 mbar), and an optical setup able to create the X-ray beam with a residual divergence of about 2-3 arcsec, HEW, and with a flux of 60 photons/s/cm2. The first beam line at the energy of 4.51 keV is now operative, and a second beam line, working at the energy of 1.49 keV, will be implemented in the coming future. The unique characteristics of the BEaTriX X-ray beam are obtained with an X-ray microfocus source placed in the focus of a paraboloidal mirror, a monochromation stage with 4 symmetrically cut crystals, and an expansion stage where the beam is diffracted and expanded by an asymmetrically-cut crystal. The beam, reflected by the MMs, is then imaged at 12 m distance, where a directly-illuminated CCD camera is placed. This paper presents the facility, the calibration of the beam and the latest results with the ATHENA MMs.
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- 2023
18. Surface-guided DIBH radiotherapy for left breast cancer: impact of different thresholds on intrafractional motion monitoring and DIBH stability
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Gnerucci, A., primary, Esposito, M., additional, Ghirelli, A., additional, Pini, S., additional, Paoletti, L., additional, Barca, R., additional, Fondelli, S., additional, Alpi, P., additional, Grilli, B., additional, Rossi, F., additional, Scoccianti, S., additional, and Russo, S., additional
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- 2022
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19. First light of BEaTriX, the new testing facility for the modular X-ray optics of the ATHENA mission
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Basso, S., primary, Salmaso, B., additional, Spiga, D., additional, Ghigo, M., additional, Vecchi, G., additional, Sironi, G., additional, Cotroneo, V., additional, Conconi, P., additional, Redaelli, E., additional, Bianco, A., additional, Pareschi, G., additional, Tagliaferri, G., additional, Sisana, D., additional, Pelliciari, C., additional, Fiorini, M., additional, Incorvaia, S., additional, Uslenghi, M., additional, Paoletti, L., additional, Ferrari, C., additional, Lolli, R., additional, Zappettini, A., additional, del Rio, M. Sanchez, additional, Parodi, G., additional, Burwitz, V., additional, Rukdee, S., additional, Hartner, G., additional, Müller, T., additional, Schmidt, T., additional, Langmeier, A., additional, Della Monica Ferreira, D., additional, Massahi, S., additional, Gellert, N. C., additional, Christensen, F., additional, Bavdaz, M., additional, Ferreira, I., additional, Collon, M., additional, Vacanti, G., additional, and Barrière, N. M., additional
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- 2022
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20. The expanded, parallel and monochromatic X-ray beam of BEaTriX:alignment and characterization
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den Herder, Jan-Willem A., Nikzad, Shouleh, Nakazawa, Kazuhiro, Basso, S., Salmaso, B., Ghigo, M., Spiga, D., Vecchi, G., Sironi, G., Cotroneo, V., Conconi, P., Redaelli, E., Bianco, A., Pareschi, G., Tagliaferri, G., Sisana, D., Pelliciari, C., Fiorini, M., Incorvaia, S., Uslenghi, M., Paoletti, L., Ferrari, C., Beretta, S., Zappettini, A., Sanchez del Rio, M., Parodi, G., Burwitz, V., Rukdee, S., Hartner, G., Müller, T., Schmidt, T., Langmeier, A., Ferreira, D. D., Massahi, S., Gellert, N. C., Christensen, F., Bavdaz, M., Ferreira, I., den Herder, Jan-Willem A., Nikzad, Shouleh, Nakazawa, Kazuhiro, Basso, S., Salmaso, B., Ghigo, M., Spiga, D., Vecchi, G., Sironi, G., Cotroneo, V., Conconi, P., Redaelli, E., Bianco, A., Pareschi, G., Tagliaferri, G., Sisana, D., Pelliciari, C., Fiorini, M., Incorvaia, S., Uslenghi, M., Paoletti, L., Ferrari, C., Beretta, S., Zappettini, A., Sanchez del Rio, M., Parodi, G., Burwitz, V., Rukdee, S., Hartner, G., Müller, T., Schmidt, T., Langmeier, A., Ferreira, D. D., Massahi, S., Gellert, N. C., Christensen, F., Bavdaz, M., and Ferreira, I.
- Abstract
BEaTriX (Beam Expander Testing X-ray) is the compact (18m × 9m) X-ray facility being implemented at INAF for the acceptance tests of the ATHENA Silicon Pore Optics Mirror Modules (MM) working at the two energies of 1.49 and 4.51 keV. It adopts an innovative design based on a collimating mirror and Bragg crystals in proper configuration to provide a large and parallel beam. The 4.51 keV line provides a parallel beam with 170 mm x 60 mm size and it has been calibrated and characterized in term of intensity, uniformity, divergence and stability. This paper traces the path taken for the best-achieved alignment of the different optical components, from the preliminary phases to the final step where the function of merit was obtained directly from the parallel beam itself. The alignment method used a combination of optical and mechanical tools: laser tracker, micro-alignment telescope (MAT), 3D measuring machine (CMM) and self-designed holed plates. The final characterization of the X-ray beam is presented.
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- 2022
21. X-ray tests of the ATHENA mirror modules in BEaTriX:from design to reality
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den Herder, Jan-Willem A., Nikzad, Shouleh, Nakazawa, Kazuhiro, Salmaso, B., Basso, S., Ghigo, M., Spiga, D., Vecchi, G., Sironi, G., Cotroneo, V., Conconi, P., Redaelli, E., Bianco, A., Pareschi, G., Tagliaferri, G., Sisana, D., Pelliciari, C., Fiorini, M., Incorvaia, S., Uslenghi, M., Paoletti, L., Ferrari, C., Lolli, R., Zappettini, A., Sanchez Del Rio, M., Parodi, G., Burwitz, V., Rukdee, S., Hartner, G., Müller, T., Schmidt, T., Langmeier, A., Ferreira, D. D., Massahi, S., Gellert, N. C., Christensen, F., Bavdaz, M., Ferreira, I., Collon, M., Vacanti, G., Barrière, N., den Herder, Jan-Willem A., Nikzad, Shouleh, Nakazawa, Kazuhiro, Salmaso, B., Basso, S., Ghigo, M., Spiga, D., Vecchi, G., Sironi, G., Cotroneo, V., Conconi, P., Redaelli, E., Bianco, A., Pareschi, G., Tagliaferri, G., Sisana, D., Pelliciari, C., Fiorini, M., Incorvaia, S., Uslenghi, M., Paoletti, L., Ferrari, C., Lolli, R., Zappettini, A., Sanchez Del Rio, M., Parodi, G., Burwitz, V., Rukdee, S., Hartner, G., Müller, T., Schmidt, T., Langmeier, A., Ferreira, D. D., Massahi, S., Gellert, N. C., Christensen, F., Bavdaz, M., Ferreira, I., Collon, M., Vacanti, G., and Barrière, N.
- Abstract
The BEaTriX (Beam Expander Testing X-ray) facility is now operative at the INAF-Osservatorio Astronomico Brera (Merate, Italy). This facility has been specifically designed and built for the X-ray acceptance tests (PSF and Effective Area) of the ATHENA Silicon Pore Optics (SPO) Mirror Modules (MM). The unique setup creates a parallel, monochromatic, large X-ray beam, that fully illuminates the aperture of the MMs, generating an image at the ATHENA focal length of 12 m. This is made possible by a microfocus X-ray source followed by a chain of optical components (a paraboloidal mirror, 2 channel cut monochromators, and an asymmetric silicon crystal) able to expand the X-ray beam to a 6 cm × 17 cm size with a residual divergence of 1.5 arcsec (vertical) × 2.5 arcsec (horizontal). This paper reports the commissioning of the 4.5 keV beam line, and the first light obtained with a Mirror Module.
- Published
- 2022
22. PO-1067 Safety and Immunogenicity of Moderna COVID vaccine in radiotherapy patients
- Author
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Scoccianti, S., primary, Delli Paoli, C., additional, Paoletti, L., additional, Grilli Leonulli, B., additional, Russo, S., additional, Alpi, P., additional, Barca, R., additional, Fondelli, S., additional, Caini, S., additional, Infantino, M., additional, Manfredi, M., additional, Esposito, M., additional, Grossi, V., additional, Furlan, F., additional, Pino, M.S., additional, Martella, F., additional, Bassetti, A., additional, Casprini, P., additional, and Fioretto, L., additional
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- 2022
- Full Text
- View/download PDF
23. PO-1710 Robustness evaluation of surface guided DIBH breast radiotherapy
- Author
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Gnerucci, A., primary, Russo, S., additional, Esposito, M., additional, Ghirelli, A., additional, Pini, S., additional, Paoletti, L., additional, Barca, R., additional, Fondelli, S., additional, Alpi, P., additional, Grilli, B., additional, Rossi, F., additional, and Scoccianti, S., additional
- Published
- 2022
- Full Text
- View/download PDF
24. Omnidirectional people's gathering monitoring by using deep learning algorithms
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Pernechele, C., Grandis, N., Bondanza, I., Capucci, A, Lessio, L., Paoletti, L., Sparc, S., Tomasin, M., Yusupova, R., and ITA
- Abstract
It has long been recognized as gathering of people is one of the major risk factor in spreading of viral epidemics. Social distancing is then one of the most simple and powerful system to mitigate the spread of infections.We explore here the possibility of monitoring public people’s gathering by using a novel bifocal omnidirectional lens designed by INAF jointly with deep learning-based algorithms. The paper briefly describe how the lens works, the applied deep learning algorithms and the preliminary results of the trials.
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- 2022
25. Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis
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Li Bassi, G., Gibbons, K., Suen, J. Y., Dalton, H. J., White, N., Corley, A., Shrapnel, S., Hinton, S., Forsyth, S., Laffey, J. G., Fan, E., Fanning, J. P., Panigada, M., Bartlett, R., Brodie, D., Burrell, A., Chiumello, D., Elhazmi, A., Esperatti, M., Grasselli, G., Hodgson, C., Ichiba, S., Luna, C., Marwali, E., Merson, L., Murthy, S., Nichol, A., Ogino, M., Pelosi, P., Torres, A., P. Y., Ng, Fraser, J. F., Al-Dabbous, T., Alfoudri, H., Shamsah, M., Elapavaluru, S., Berg, A., Horn, C., Mayasi, Y., Schroll, S., Meyer, D., Velazco, J., Ploskanych, L., Fikes, W., Bagewadi, R., Dao, M., White, H., Ehlers, A., Shalabi-McGuire, M., Witt, T., Grazioli, L., Lorini, L., Grandin, E. W., Nunez, J., Reyes, T., Obriain, D., Hunter, S., Ramanan, M., Affleck, J., Veerendra, H. H., Rai, S., Russell-Brown, J., Nourse, M., Joseph, M., Mitchell, B., Tenzer, M., Abe, R., Cho, H. J., Jeong, I. S., Rahman, N., Kakar, V., Brozzi, N., Mehkri, O., Krishnan, S., Duggal, A., Houltham, S., Graf, J., Diaz, R., Orrego, R., Delgado, C., Gonzalez, J., Sanchez, M. S., Piagnerelli, M., Sarrazin, J. V., Zabert, A. /P. G., Espinosa, L., Delgado, P., Delgado, V., Rincon, D. F. B., Yanten, A. M. M., Duque, M. B., Al-Hudaib, A., Callahan, M., Taufik, M. A., Wardoyo, E. Y., Gunawan, M., Trisnaningrum, N. S., Irawany, V., Rayhan, M., Pesenti, A., Zanella, A., Leone, M., Coppola, S., Colombo, S., Antonelli, M., Carelli, S., Grieco, D. L., Asaki, M., Hoshino, K., Salazar, L., Duarte, L., Laffey, J., Mcnicholas, B., Cosgrave, D., Mccaffrey, J., Bone, A., Hakeem, Y., Winearls, J., Tallott, M., Thomson, D., Arnold-Day, C., Cupido, J., Fanie, Z., Miller, M., Seymore, L., van Straaten, D., Hssain, A. A., Aliudin, J., Alqahtani, A. -R., Mohamed, K., Mohamed, A., Tan, D., Villanueva, J., Zaqout, A., Kurtzman, E., Ademi, A., Dobrita, A., El Aoudi, K., Segura, J., Giwangkancana, G., Ohshimo, S., Hitoshi, S., Osatnik, J., Joosten, A., Yang, M., Motos, A., Arancibia, F., Williams, V., Noel, A., Luque, N., Trung, T. H., Yacoub, S., Fantini, M., Garcia, R. N. J., Alvarez, E. C., Greti, A., Ceccato, A., Sanchez, A., Vazquez, A. L., Roche-Campo, F., Franch-Llasat, D., Tuazon, D., Amato, M., Cassimiro, L., Pola, F., Ribeiro, F., Fonseca, G., Dalton, H., Desai, M., Osborn, E., Deeb, H., Arcadipane, A., Martucci, G., Panarello, G., Vitiello, C., Bianco, C., Occhipinti, G., Rossetti, M., Cuffaro, R., Cho, S. -M., Shimizu, H., Moriyama, N., Kim, J. -B., Kitamura, N., Gebauer, J., Yokoyama, T., Al-Fares, A., Buabbas, S., Alamad, E., Alawadhi, F., Alawadi, K., Tanaka, H., Hashimoto, S., Yamazaki, M., T. -H., Oh, Epler, M., Forney, C., Kruse, L., Feister, J., Williamson, J., Grobengieser, K., Gnall, E., Golden, S., Caroline, M., Shapiro, T., Karaj, C., Thome, L., Sher, L., Vanderland, M., Welch, M., Mcdermott, S., Brain, M., Mineall, S., Kimura, D., Brazzi, L., Sales, G., Ogston, T., Nagpal, D., Fischer, K., Lorusso, R., Rangappa, R., Appu, A., Carton, E. G., Sen, A., Palacios, A., Rainey, D., Samoukoviv, G., Campisi, J., Durham, L., Neumann, E., Seefeldt, C., Falcucci, O., Emmrich, A., Guy, J., Johns, C., Potzner, K., Zimmermann, C., Espinal, A., Buchtele, N., Schwameis, M., Stecher, S. -S., Singh, D., Barnikel, M., Arenz, L., Zaaqoq, A., Galloway, L. A., Merley, C., Csete, M., Quesada, L., Saba, I., Kasugai, D., Hiraiwa, H., Tanaka, T., Purnama, Y., Dewayanti, S. R., Ardiyan, Juzar, D. A., Siagian, D., Chen, Y. -S., Ratsep, I., Oigus, G., Erikson, K., Post, A. -M., Enneveer, L., Sillaots, P., Manetta, F., Mihelis, E., Sarmiento, I. C., Narasimhan, M., Varrone, M., Komats, M., Garcia-Diaz, J., Harmon, C., Satyapriya, S. V., Bhatt, A., Mokadam, N. A., Uribe, A., Gonzalez, A., Shi, H., Mckeown, J., Pasek, J., Fiorda, J., Echeverria, M., Moreno, R., Zakhary, B., Cavana, M., Cucino, A., Foti, G., Giani, M., Russotto, V., Castagna, V., Dellamore, A., Navalesi, P., Shum, H. -P., Vuysteke, A., Usman, A., Acker, A., Smood, B., Mergler, B., Sertic, F., Subramanian, M., Sperry, A., Rizer, N., Burhan, E., Rasmin, M., Akmal, E., Sitompul, F., Lolong, N., Naivedh, B., Erickson, S., Barrett, P., Dean, D., Daugherty, J., Loforte, A., Khan, I., Abraar Quraishi, M., Desantis, O., So, D., Kandamby, D., Mandei, J. M., Natanael, H., Yudhalantang, E., Lantang, A., Wijaya, S. O., Jung, A., Ng, G., W. Y., Ng, Fang, S., Tabah, A., Ratcliffe, M., Duroux, M., Adachi, S., Nakao, S., Blanco, P., Prieto, A., Sanchez, J., Nicholson, M., Butt, W., Serratore, A., Delzoppo, C., Janin, P., Yarad, E., Totaro, R., Coles, J., Pujo, B., Balk, R., Vissing, A., Kapania, E., Hays, J., Fox, S., Yantosh, G., Mishin, P., Yuliarto, S., Hari Santoso, K., Djajalaksana, S., Fatoni, A. Z., Fukuda, M., Liu, K., Battaglini, D., Jimenez, J. F. M., Bastos, D., Gaiao, S., Rusmawatiningtyas, D., Buchner, J., Cho, Y. -J., Lee, S. H., Kawasaki, T., Munshi, L., Sakiyalak, P., Nitayavardhana, P., Seitz, T., Arora, R., Kent, D., Marino, D., Parwar, S., Cheng, A., Miller, J., Fujitani, S., Shimizu, N., Madhok, J., Owyang, C., Buscher, H., Reynolds, C., Maasikas, O., Beljantsev, A., Mihnovits, V., Akimoto, T., Aizawa, M., Horibe, K., Onodera, R., Young, M., George, T., Shekar, K., Mcguinness, N., Irvine, L., Flynn, B., Endo, T., Sugiyama, K., Shimizu, K., Exconde, K., Lussier, L., Lotz, G., Malfertheiner, M., Maier, L., Dreier, E., Kusumastuti, N. P., Mccloskey, C., Dabaliz, A. -A., Elshazly, T. B., Smith, J., Szuldrzynski, K. S., Bielanski, P., Wille, K., Parhar, K. K. S., Fiest, K. M., Codan, C., Shahid, A., Fayed, M., Evans, T., Garcia, R., Gutierrez, A., Song, T., Rose, R., Bennett, S., Richardson, D., Peek, G., Arora, L., Rappapport, K., Rudolph, K., Sibenaller, Z., Stout, L., Walter, A., Herr, D., Vedadi, N., Thompson, S., Sindt, L., Rajnic, S., Ewald, C., Hoffman, J., Ying, X., Kennedy, R., Griffee, M., Ciullo, A., Kida, Y., Roca, R. F., Riera, J. I., Contreras, S., Alegre, C., Kay, C., Fischer, I., Renner, E., Taniguci, H., Fraser, J., Bassi, G. L., Suen, J., Barnett, A., Pearse, I., Abbate, G., Hassan, H., Heinsar, S., Karnik, V. A., Ki, K., Oneill, H. F., Obonyo, N., Pimenta, L. P., Reid, J. D., Sato, K., Vuorinen, A., Wildi, K. S., Wood, E. S., Yerkovich, S., Lee, J., Plotkin, D., Citarella, B. W., Hartley, E., Lubis, B., Ikeyama, T., Bhaskar, B., Jung, J. -S., Mcguinness, S., Eastwood, G., Marta, S. R., Guarracino, F., Gerle, S., Coxon, E., Claro, B., Loverde, D., Patil, N., Parrini, V., Mcbride, A., Negaard, K., Ratsch, A., Abdelaziz, A., Uribe, J. D., Peris, A., Sanders, M., Emerson, D., Kamal, M., Povoa, P., Francis, R., Cherif, A., Joseph, S., Di Nardo, M., Heard, M., Kyle, K., Blackwell, R. A., Biston, P., Jeong, H. W., Smith, R., Prawira, Y., Montrucchio, G., Garcia, A. H., Salterain, N., Meyns, B., Moreno, M., Walia, R., Mehta, A., Schweda, A., Supriatna, M., Kirakli, C., Williams, M., Kim, K. H., Assad, A., Giraldo, E., Karolak, W., Balik, M., Pocock, E., Gajkowski, E., Masafumi, K., Barrett, N., Takeyama, Y., Park, S., Amin, F., Andriyani, F. M., Sudakevych, S., Vera, M., Cornejo, R., Schwarz, P., Mardini, A. C., de Paula, T., Neto, A. S., Villoldo, A., Colafranceschi, A. S., Iglesias, A. U., Granjean, J., Melro, L. M. G., Romualdo, G. F., Gaia, D., Souza, H., Galas, F., Mendiluce, R. M., Sosa, A., Martinez, I., Kurosawa, H., Salgado, J., Hugi-MayrCharbonneau, B. E., Barzilai, V. S., Monteiro, V., de Souza, R. R., Harper, M., Suzuki, H., Adams, C., Brieva, J., Nyale, G., Eltatar, F. S., Fatani, J., Baeissa, H., Masri, A. A., Rabie, A., Hui, M. Y., Yamane, M., Jung, H., Margaret, A. M., Nacpil, N., Ruck, K., Bakken, R., Jara, C., Felton, T., Berra, L., Shah, B., Chakraborty, A., Cardona, M., Capatos, G., Akkanti, B., Orija, A., Jain, H., Ito, A., Housni, B., Low, S., Iihara, K., Chavez, J., Ramanathan, K., Zabert, G., Naidoo, K., Seppelt, I., Vandyk, M., Macdonald, S., Mcgregor, R., Siebenaler, T., Flynn, H., Lofton, K., Aokage, T., Shigemitsu, K., Moscatelli, A., Fiorentino, G., Baumgaertel, M., Mba, S. E., Assy, J., Hutahaean, A., Roush, H., Sichting, K. A., Alessandri, F., Burns, D., Salt, G., Garabedian, C. P., Millar, J., Sim, M., Mattke, A., Mcauley, D., Tadili, J., Frenzel, T., Bar-Lavie, Y., Ortiz, A. B., Stone, J., Attokaran, A., Farquharson, M., Patel, B., Gunning, D., Baillie, K., Watson, P., Tamai, K., Sajinadiyasa, G. K., Kanyawati, D., Salgado, M., Sassine, A., Yudo, B., Mccaul, S., Lee, B., Lee, S. M., Afek, A., Iwashita, Y., Semedi, B. P., Metiva, J., Van Belle, N., Martin-Loeches, I., Ivatt, L., Woon, C. Y., Kang, H. M., Smith, T., James, E., Al-Rawas, N., Iwasaki, Y., King-Chung, K. C., Gudzenko, V., Hugi-Mayr, B., Taccone, F., Perdhana, F., Lamarche, Y., Ribeiro, J. M., Bradic, N., Van den Bossche, K., Lansink, O., Singh, G., Debeuckelaere, G., Stelfox, H. T., Yi, C., Elia, J., Tribble, T., Shankar, S., Padmanabhan, R., Hallinan, B., Paoletti, L., Leyva, Y., Fykuda, T., Badulak, J., Koch, J., Hackman, A., Janowaik, L., Hernandez, D., Osofsky, J., Donadello, K., Lawang, A., Fine, J., Davidson, B., Vazquez, A. O. R., COVID-19 Critical Care Consortium, and Consortium, COVID-19 Critical Care
- Subjects
Male ,Respiratory Distress Syndrome ,COVID-19 ,Intensive care unit ,Mechanical ventilation ,Neuromuscular blocking agent ,SARS-CoV-2 ,Aged ,Female ,Humans ,Intensive Care Units ,Middle Aged ,Propensity Score ,Respiration, Artificial ,Neuromuscular Blocking Agents ,Respiration ,Other Research Radboud Institute for Health Sciences [Radboudumc 0] ,Settore MED/41 - Anestesiologia ,Critical Care and Intensive Care Medicine ,COVID-19 Drug Treatment ,Artificial ,Human medicine - Abstract
Background The role of neuromuscular blocking agents (NMBAs) in coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS) is not fully elucidated. Therefore, we aimed to investigate in COVID-19 patients with moderate-to-severe ARDS the impact of early use of NMBAs on 90-day mortality, through propensity score (PS) matching analysis. Methods We analyzed a convenience sample of patients with COVID-19 and moderate-to-severe ARDS, admitted to 244 intensive care units within the COVID-19 Critical Care Consortium, from February 1, 2020, through October 31, 2021. Patients undergoing at least 2 days and up to 3 consecutive days of NMBAs (NMBA treatment), within 48 h from commencement of IMV were compared with subjects who did not receive NMBAs or only upon commencement of IMV (control). The primary objective in the PS-matched cohort was comparison between groups in 90-day in-hospital mortality, assessed through Cox proportional hazard modeling. Secondary objectives were comparisons in the numbers of ventilator-free days (VFD) between day 1 and day 28 and between day 1 and 90 through competing risk regression. Results Data from 1953 patients were included. After propensity score matching, 210 cases from each group were well matched. In the PS-matched cohort, mean (± SD) age was 60.3 ± 13.2 years and 296 (70.5%) were male and the most common comorbidities were hypertension (56.9%), obesity (41.1%), and diabetes (30.0%). The unadjusted hazard ratio (HR) for death at 90 days in the NMBA treatment vs control group was 1.12 (95% CI 0.79, 1.59, p = 0.534). After adjustment for smoking habit and critical therapeutic covariates, the HR was 1.07 (95% CI 0.72, 1.61, p = 0.729). At 28 days, VFD were 16 (IQR 0–25) and 25 (IQR 7–26) in the NMBA treatment and control groups, respectively (sub-hazard ratio 0.82, 95% CI 0.67, 1.00, p = 0.055). At 90 days, VFD were 77 (IQR 0–87) and 87 (IQR 0–88) (sub-hazard ratio 0.86 (95% CI 0.69, 1.07; p = 0.177). Conclusions In patients with COVID-19 and moderate-to-severe ARDS, short course of NMBA treatment, applied early, did not significantly improve 90-day mortality and VFD. In the absence of definitive data from clinical trials, NMBAs should be indicated cautiously in this setting.
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- 2022
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26. Targeting Hedgehog signaling pathway by a natural compound: a promising approach for anti-cancer therapeutic development in Intrahepatic Cholangiocarcinoma
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Paradiso, S., Carpino, G., Quaglio, D., Ghirga, F., Di Meo, C., Paoletti, L., De Luca, T., Franchitto, M., Di Marcotullio, L., Infante, P., Gaudio, E., Alvaro, D., and Cardinale, V.
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- 2024
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27. Special stereotactic radiotherapy techniques: procedures and equipment for treatment simulation and dose delivery
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Paoletti, L., Ceccarelli, C., Menichelli, C., Aristei, C., Borghesi, S., Tucci, E., Bastiani, P., and Cozzi, S.
- Subjects
Frame-based stereotactic radiotherapy ,Oncology ,Frame-less stereotactic radiotherapy ,Stereotactic radiotherapy ,Image-guided radiotherapy ,Radiology, Nuclear Medicine and imaging ,Organ motion ,Radiosurgery - Abstract
Stereotactic radiotherapy (SRT ) is a multi-step procedure with each step requiring extreme accuracy. Physician-dependent accuracy includes appropriate disease staging, multi-disciplinary discussion with shared decision-making, choice of morphological and functional imaging methods to identify and delineate the tumor target and organs at risk, an image-guided patient set-up, active or passive management of intra-fraction movement, clinical and instrumental follow-up. Medical physicist-dependent accuracy includes use of advanced software for treatment planning and more advanced Quality Assurance procedures than required for conventional radiotherapy. Consequently, all the professionals require appropriate training in skills for high-quality SRT. Thanks to the technological advances, SRT has moved from a "frame-based" technique, i.e. the use of stereotactic coordinates which are identified by means of rigid localization frames, to the modern "frame-less" SRT which localizes the target volume directly, or by means of anatomical surrogates or fiducial markers that have previously been placed within or near the target. This review describes all the SRT steps in depth, from target simulation and delineation procedures to treatment delivery and image-guided radiation therapy. Target movement assessment and management are also described.
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- 2021
28. Mineral Particulate in the Lung Parenchyma of Subjects Not Occupationally Exposed to Dust
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Paoletti, L., Falchi, M., Batisti, D., Carrieri, M. P., Petrelli, M. G., Ciallella, C., Donelli, G., and Bignon, Jean, editor
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- 1990
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29. Serotypes VI and VIII Predominate among Group B Streptococci Isolated from Pregnant Japanese Women
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Lachenauer, C. S., Kasper, D. L., Shimada, J., Ichiman, Y., Ohtsuka, H., Kaku, M., Paoletti, L. C., Ferrieri, P., and Madoff, L. C.
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- 1999
30. Building the BEaTriX facility for the ATHENA mirror modules X-ray testing
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O'Dell, Stephen L., Gaskin, Jessica A., Pareschi, Giovanni, Salmaso, B., Basso, S., Cotroneo, V., Ghigo, M., Pareschi, G., Redaelli, E., Sironi, G., Spiga, D., Tagliaferri, G., Vecchi, G., Fiorini, M., Incorvaia, S., Uslenghi, M., Paoletti, L., Ferrari, C., Zappettini, A., Lolli, R., Sanchez Del Rio, M., Burwitz, V., Christensen, F., Ferreira, D. D., Gellert, N. C., Massahi, S., Bavdaz, M., Ferreira, I., O'Dell, Stephen L., Gaskin, Jessica A., Pareschi, Giovanni, Salmaso, B., Basso, S., Cotroneo, V., Ghigo, M., Pareschi, G., Redaelli, E., Sironi, G., Spiga, D., Tagliaferri, G., Vecchi, G., Fiorini, M., Incorvaia, S., Uslenghi, M., Paoletti, L., Ferrari, C., Zappettini, A., Lolli, R., Sanchez Del Rio, M., Burwitz, V., Christensen, F., Ferreira, D. D., Gellert, N. C., Massahi, S., Bavdaz, M., and Ferreira, I.
- Abstract
BEaTriX (Beam Expander Testing X-ray) is the X-ray facility under construction at the INAF-Osservatorio Astronomico Brera (Merate, Italy) to prove that it is possible to perform the X-ray acceptance tests (PSF and Aeff) of the ATHENA mirror modules at the required rate and with the required accuracy. The unique optical setup makes use of a micro-focus X-ray source with anode in Titanium, a paraboloidal mirror with small radius of curvature, and a set of crystals to monochromate and expand the beam to fully illuminate the entrance pupil of the ATHENA MMs. The quality of the optical components, and their precise alignment, guarantees the production of a parallel beam at 4.51 keV, to be extended in a second phase to 1.49 keV in order to complete the acceptance requirements for the ATHENA MMs. The completion of the facility is expected to occur in July this year, while the commissioning will start in September. In this paper, we present the current status.
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- 2021
31. Non-fibrous Inorganic Particles in Bronchoalveolar Lavage Fluid of Pottery Workers
- Author
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Falchi, M., Paoletti, L., Mariotta, S., Giosue, S., Guidi, L., Biondo, L., Scavalli, P., and Bisetti, A.
- Published
- 1996
32. A pilot study on the content and the release of Ni and other allergenic metals from cheap earrings available on the Italian market
- Author
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Bocca, B., Forte, G., Senofonte, O., Violante, N., Paoletti, L., De Berardis, B., Petrucci, F., and Cristaudo, A.
- Published
- 2007
- Full Text
- View/download PDF
33. Airborne silica levels in an urban area
- Author
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De Berardis, B., Incocciati, E., Massera, S., Gargaro, G., and Paoletti, L.
- Published
- 2007
- Full Text
- View/download PDF
34. Geo-volcanological, mineralogical and environmental aspects of quarry materials related to pleural neoplasm in the area of Biancavilla, Mount Etna (Eastern Sicily, Italy)
- Author
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Burragato, F., Comba, P., Baiocchi, V., Palladino, D. M., Simei, S., Gianfagna, A., Paoletti, L., and Pasetto, R.
- Published
- 2005
- Full Text
- View/download PDF
35. (1069) Lung Waitlist and Transplantation Outcomes after the Affordable Care Act's Medicaid Expansion
- Author
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Kern, Q., Shorbaji, K., Gibney, B., Paoletti, L., Whelan, T., Kilic, A., and Hashmi, Z.
- Published
- 2023
- Full Text
- View/download PDF
36. (1070) Changes in Patient Selection and Outcomes in the New Lung Transplant Allocation Era
- Author
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Blanding, W., Shorbaji, K., Welch, B., Gibney, B., Paoletti, L., Whelan, T., Kilic, A., and Hashmi, Z.
- Published
- 2023
- Full Text
- View/download PDF
37. Nature and extent of the exposure to fibrous amphiboles in Biancavilla
- Author
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Bruni, B.M., Pacella, A., MazziottiTagliani, S., Gianfagna, A., and Paoletti, L.
- Published
- 2006
- Full Text
- View/download PDF
38. Influence of tobacco smoke on indoor PM 10 particulate matter characteristics
- Author
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Paoletti, L., De Berardis, B., Arrizza, L., and Granato, V.
- Published
- 2006
- Full Text
- View/download PDF
39. Multinucleation and pro-inflammatory cytokine release promoted by fibrous fluoro-edenite in lung epithelial A549 cells
- Author
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Travaglione, S., Bruni, B.M., Falzano, L., Filippini, P., Fabbri, A., Paoletti, L., and Fiorentini, C.
- Published
- 2006
- Full Text
- View/download PDF
40. PO-1621: Surface Guided Radiotherapy for locoregional DIBH treatment: Intrafraction motion evaluation
- Author
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Gnerucci, A., primary, Russo, S., additional, Esposito, M., additional, Ghirelli, A., additional, Pini, S., additional, Rossi, F., additional, Paoletti, L., additional, Barca, R., additional, Fondelli, S., additional, Alpi, P., additional, Grilli, B., additional, and Bastiani, P., additional
- Published
- 2020
- Full Text
- View/download PDF
41. PD-0182: Elastically deformed planning CT improves in vivo dosimetry results for Head and Neck treatments
- Author
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Esposito, M., primary, Ghirelli, A., additional, Pini, S., additional, Russo, S., additional, Alpi, P., additional, Barca, R., additional, Fondelli, S., additional, Leonulli, B. Grilli, additional, Paoletti, L., additional, Rossi, F., additional, and Bastiani, P., additional
- Published
- 2020
- Full Text
- View/download PDF
42. The expanded, parallel, and monochromatic x-ray beam of BEaTriX: alignment and characterization
- Author
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den Herder, Jan-Willem A., Nikzad, Shouleh, Nakazawa, Kazuhiro, Basso, S., Salmaso, B., Ghigo, M., Spiga, D., Vecchi, G., Sironi, G., Cotroneo, V., Conconi, P., Redaelli, E., Bianco, A., Pareschi, G., Tagliaferri, G., Sisana, D., Pelliciari, C., Fiorini, M., Incorvaia, S., Uslenghi, M., Paoletti, L., Ferrari, C., Beretta, S., Zappettini, A., del Rio, M. Sanchez .., Parodi, G., Burwitz, V., Rukdee, S., Hartner, G., Müller, T., Schmidt, T., Langmeier, A., Ferreira, D. D., Massahi, S., Gellert, N. C., Christensen, F., Bavdaz, M., and Ferreira, I.
- Published
- 2022
- Full Text
- View/download PDF
43. X-ray tests of the ATHENA mirror modules in BEaTriX: from design to reality
- Author
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den Herder, Jan-Willem A., Nikzad, Shouleh, Nakazawa, Kazuhiro, Salmaso, B., Basso, S., Ghigo, M., Spiga, D., Vecchi, G., Sironi, G., Cotroneo, V., Conconi, P., Redaelli, E., Bianco, A., Pareschi, G., Tagliaferri, G., Sisana, D., Pelliciari, C., Fiorini, M., Incorvaia, S., Uslenghi, M., Paoletti, L., Ferrari, C., Lolli, R., Zappettini, A., Sanchez del Rio, M., Parodi, G., Burwitz, V., Rukdee, S., Hartner, G., Müller, T., Schmidt, T., Langmeier, A., Ferreira, D. D., Massahi, S., Gellert, N. C., Christensen, F., Bavdaz, M., Ferreira, I., Collon, M., Vacanti, G., and Barrière, N.
- Published
- 2022
- Full Text
- View/download PDF
44. The control software of the BEaTriX x-ray beam calibration facility: problems and solutions
- Author
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Ibsen, Jorge, Chiozzi, Gianluca, Ghigo, M., Salmaso, B., Basso, S., Spiga, D., and Paoletti, L.
- Published
- 2022
- Full Text
- View/download PDF
45. Yawning distribution across 24 h in preterm and near term infants: P048
- Author
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GIGANTI, F., PAOLETTI, L., HAYES, M., BERTINI, G., CIONI, G., and SALZARULO, P.
- Published
- 2006
46. In vitro effects on macrophages induced by noncytotoxic doses of silica particles possibly relevant to ambient exposure
- Author
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Balduzzi, M, Diociaiuti, M, De Berardis, B, Paradisi, S, and Paoletti, L
- Published
- 2004
- Full Text
- View/download PDF
47. Is DIBH more robust than FB in VMAT left breast irradiation? Multicenter and multivendor analysis
- Author
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Universitat Rovira i Virgili, Russo, S; Esposito, M; Hernandez, V; Saez, J; Nicolini, G; Vanetti, E; Rossi, F; Paoletti, L; Bastiani, P; Reggiori, G; Tomatis, S; Scorsetti, M; Mancosu, P, Universitat Rovira i Virgili, and Russo, S; Esposito, M; Hernandez, V; Saez, J; Nicolini, G; Vanetti, E; Rossi, F; Paoletti, L; Bastiani, P; Reggiori, G; Tomatis, S; Scorsetti, M; Mancosu, P
- Published
- 2019
48. Influence of Particle Size and Chemical Composition on Efficiency of Clearance Mechanisms: Electron Microscopy Studies on Humans
- Author
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Falchi, M., Donelli, G., and Paoletti, L.
- Published
- 1994
- Full Text
- View/download PDF
49. Seasonal effects on the physico-chemical characteristics of PM2.1 in Rome: a study by SEM and XPS
- Author
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Paoletti, L., De Berardis, B., Arrizza, L., Passacantando, M., Inglessis, M., and Mosca, M.
- Published
- 2003
- Full Text
- View/download PDF
50. EP-1847 Automatic optimization of Head and Neck treatments with multicriteria radiobiological cost functions
- Author
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Esposito, M., primary, Ghirelli, A., additional, Pini, S., additional, Russo, S., additional, Zatelli, G., additional, Alpi, P., additional, Barca, R., additional, Fondelli, S., additional, Grilli Leonulli, B., additional, Paoletti, L., additional, Rossi, F., additional, and Bastani, P., additional
- Published
- 2019
- Full Text
- View/download PDF
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