Search

Rabbit oncology is gaining more attention as more pet rabbits are surviving beyond their normal lifespans. Due to the limited epidemiological information on pet rabbits’ tumors in Thailand, this study aimed to report the prevalence and the potential risk factors associated with tumors in pet rabbits in Thailand. From 2018 to 2022, 93 tissue biopsies from tumor-suspected lesions on pet rabbits were gathered from animal hospitals in Bangkok and Chonburi provinces, Thailand. According to histopathology confirmation, tumors and tumor-like lesions were diagnosed. In this study, the overall tumors were 67.74% (n=63) out of the submitted cases (n=93). The most commonly affected organ systems were reproduction (65.08%) and integumentary (22.22%). Rabbits older than 5 years were 3.85 times more likely to have reproductive tumors than younger rabbits (95% confidence interval (CI): 1.45–10.27, P≤0.01), and the most frequently occurring tumor type was uterine adenocarcinoma. Furthermore, male rabbits had a 17.02 times higher probability of developing cutaneous tumors than female rabbits (95% CI: 4.19–69.11, P≤0.001), and the most frequently occurring tumor type was soft tissue sarcoma. The results of this study thus suggested that the age and sex of the rabbits were potential risk factors for tumor development in Thailand. The knowledge gained from our study also provided the recommendation for owners to monitor their rabbits’ health annually, particularly after late middle age, and rendered guidance for tumor detection in practical clinics. [ABSTRACT FROM AUTHOR]

Canine transmissible venereal tumor (TVT) is a contagious neoplastic disease commonly seen in tropical and subtropical areas in the countries where the control of stray dog population is poor. This study aimed to summarize the current disease status and evaluate factors affecting treatment outcome to vincristine sulfate, which is the chemotherapeutic drug of choice. Studied factors were divided into three categories; general background (i.e. age, gender, breed), specific descriptions (i.e. tumor diameter, tumor site, season of the year), and treatment details (number of vincristine shots, meteorological parameters). One hundred and fifty-seven medical records were included with 100 achieved complete treatments and enrolled in the investigation of treatment outcome. Treatment outcome was classified as complete remission (CR) and partial remission (PR) at the eighth week of treatment. Moreover, the corresponding factors affecting number of vincristine shot to commit CR were evaluated. The age, gender and breed had no effect on treatment outcome or number of vincristine shots. The tumors at the genital area were prone to be recovered (CR) than the others (P = 0.08). The tumors with diameter >6 cm required higher number of vincristine shots than that of diameter <2 cm (P = 0.05). Moreover, there was a tendency that CR was observed with lower mean temperature at 60 days after enrolled (Temp60) and lower maximal temperature (MaxTemp60) than the PR cases (P = 0.08 and P = 0.07, respectively). These results may contribute to the prognosis of the treatment with vincristine sulfate particularly when the treatment is influenced by tumor site, tumor size, and climate. [ABSTRACT FROM AUTHOR]