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3. Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis

Author

Dmytriw, Adam A., Salim, Hamza, Musmar, Basel, Aslan, Assala, Cancelliere, Nicole M., McLellan, Rachel M., Algin, Oktay, Ghozy, Sherief, Dibas, Mahmoud, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Carnevale, Joseph, Saliou, Guillaume, Mastorakos, Panagiotis, Naamani, Kareem El, Shotar, Eimad, Premat, Kevin, Möhlenbruch, Markus, Kral, Michael, Doron, Omer, Chung, Charlotte, Salem, Mohamed M., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad U., Catapano, Joshua, Waqas, Muhammad, Tutino, Vincent M., Ibrahim, Mohamed K., Mohammed, Marwa A., Imamoglu, Cetin, Bayrak, Ahmet, Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer E., Ogilvie, Mark, Sporns, Peter, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie T., Psychogios, Marios, Ulfert, Christian, Diestro, Jose Danilo Bengzon, Pukenas, Bryan, Burkhardt, Jan-Karl, Huynh, Thien, Martinez-Gutierrez, Juan Carlos, Essibayi, Muhammed Amir, Sheth, Sunil A., Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberfalzer, Monika, Griessenauer, Christoph J., Asadi, Hamed, Siddiqui, Adnan, Brook, Allan L., Altschul, David, Ducruet, Andrew F., Albuquerque, Felipe C., Regenhardt, Robert W., Stapleton, Christopher J., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Tjoumakaris, Stavropoula I., Clarençon, Frédéric, Limbucci, Nicola, Cuellar-Saenz, Hugo H., Jabbour, Pascal M., Pereira, Vitor Mendes, Patel, Aman B., and Adeeb, Nimer

Published
2024
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6. Long-Term Follow-Up of Cerebral Aneurysms Completely Occluded at 6 Months After Intervention with the Woven EndoBridge (WEB) Device: a Retrospective Multicenter Observational Study

Author

El Naamani, Kareem, Mastorakos, Panagiotis, Adeeb, Nimer, Lan, Mathews, Castiglione, James, Khanna, Omaditya, Diestro, Jose Danilo Bengzon, McLellan, Rachel M., Dibas, Mahmoud, Vranic, Justin E., Aslan, Assala, Cuellar-Saenz, Hugo H., Guenego, Adrien, Carnevale, Joseph, Saliou, Guillaume, Ulfert, Christian, Möhlenbruch, Markus, Foreman, Paul M., Vachhani, Jay A., Hafeez, Muhammad U., Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Michelozzi, Caterina, Spears, Julian, Panni, Pietro, Griessenauer, Christoph J., Asadi, Hamed, Regenhardt, Robert W., Stapleton, Christopher J., Ghozy, Sherief, Siddiqui, Adnan, Patel, Nirav J., Kan, Peter, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Zanaty, Mario, Ghosh, Ritam, Abbas, Rawad, Amllay, Abdelaziz, Tjoumakaris, Stavropoula I., Gooch, Michael R., Cancelliere, Nicole M., Herial, Nabeel A., Rosenwasser, Robert H., Zarzour, Hekmat, Schmidt, Richard F., Pereira, Vitor Mendes, Patel, Aman B., Jabbour, Pascal, and Dmytriw, Adam A.

Published
2024
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8. Advancing Racial Equity with the Aquarium Conservation Partnership

Author

Jaclyn N. Wegner and Kera Abraham Panni

Abstract

Historic and present-day systemic racism frequently excludes Black, Indigenous, and people of color (BIPOC) from engaging in aquarium efforts toward conservation, research, advocacy, and education. But to realize the conservation missions of aquariums--creating a more equitable and sustainable world in which people and nature thrive--we need a diversity of perspectives and voices driving adaptive, lasting solutions. In this article, the co-authors describe how a diverse coalition of U.S. aquariums is working to integrate racial justice with their conservation initiatives and to transform their sector. They outline the formation of the Aquarium Conservation Partnership (ACP) Equity Work Group, progress toward an ACP Equity Commitment, and the restructuring of ACP governance. They describe how these efforts, like equity work across the broader cultural attractions sector, have been imperfect and uncertain; but they yield lessons that may provide reassurance, encouragement, and guidance to similar coalitions committed to racial equity.

Published
2024
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9. Long-term responders to nivolumab in previously treated advanced renal cell carcinoma: a sub-analysis of meet-URO15 study

Author

Messina, Carlo, Catalano, Martina, Roviello, Giandomenico, Gandini, Annalice, Maruzzo, Marco, De Giorgi, Ugo, Pedrazzoli, Paolo, Sbrana, Andrea, Zucal, Paolo Andrea, Masini, Cristina, Naglieri, Emanuele, Procopio, Giuseppe, Milella, Michele, Catalano, Fabio, Fratino, Lucia, Pipitone, Stefania, Ricotta, Riccardo, Panni, Stefano, Mollica, Veronica, Soraru, Mariella, Prati, Veronica, Atzori, Francesco, Di Napoli, Marilena, Messina, Marco, Morelli, Franco, Prati, Giuseppe, Nole, Franco, Malgeri, Andrea, Tudini, Marianna, Vignani, Francesca, Cavo, Alessia, Signori, Alessio, Banna, Giuseppe Luigi, Rescigno, Pasquale, Buti, Sebastiano, Rebuzzi, Sara Elena, and Fornarini, Giuseppe

Published
2024
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10. Mixed finite element method for a beam equation with the p-biharmonic operator

Author

Almeida, Rui M. P., Duque, José C. M., Ferreira, Jorge, and Panni, Willian S.

Subjects
Mathematics - Numerical Analysis, Mathematics - Analysis of PDEs, 35A01, 35D30, 35J40, 65N30
Abstract

In this paper, we consider a nonlinear beam equation with the p-biharmonic operator, where $1 < p < \infty$. Using a change of variable, we transform the problem into a system of differential equations and prove the existence, uniqueness and regularity of the weak solution by applying the Lax-Milgram theorem and classical results of functional analysis. We investigate the discrete formulation for that system and, with the aid of the Brouwer theorem, we show that the problem has a discrete solution. The uniqueness and stability of the discrete solution are obtained through classical methods. After establishing the order of convergence, we apply the mixed finite element method to obtain an algebraic system of equations. Finally, we implement the computational codes in Matlab software and perform the comparison between theory and simulations.

Published
2022

12. Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology

Author

Panni, Usman Y., Chen, Michael Y., Zhang, Felicia, Cullinan, Darren R., Li, Lijin, James, C. Alston, Zhang, Xiuli, Rogers, S., Alarcon, A., Baer, John M., Zhang, Daoxiang, Gao, Feng, Miller, Christopher A., Gong, Qingqing, Lim, Kian-Huat, DeNardo, David G., Goedegebuure, S. Peter, Gillanders, William E., and Hawkins, William G.

Published
2023
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13. The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Dibas, Mahmoud, Ghozy, Sherief, Adeeb, Nimer, Diestro, Jose Danilo Bengzon, Phan, Kevin, Cuellar-Saenz, Hugo H., Sweid, Ahmad, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Saliou, Guillaume, Möhlenbruch, Markus, Regenhardt, Robert W., Vranic, Justin E., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer, Salehani, Arsalaan, Sporns, Peter, Jones, Jesse, Psychogios, Marios, Spears, Julian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Stapleton, Christopher J., Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Tjoumakaris, Stavropoula, Knopman, Jared, Aziz-Sultan, Mohammad A., Limbucci, Nicola, Jabbour, Pascal, Cognard, Christophe, and Patel, Aman B.

Published
2023
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14. The IntAct database: efficient access to fine-grained molecular interaction data

Author

del Toro, Noemi, Shrivastava, Anjali, Ragueneau, Eliot, Meldal, Birgit, Combe, Colin, Barrera, Elisabet, Perfetto, Livia, How, Karyn, Ratan, Prashansa, Shirodkar, Gautam, Lu, Odilia, Mészáros, Bálint, Watkins, Xavier, Pundir, Sangya, Licata, Luana, Iannuccelli, Marta, Pellegrini, Matteo, Martin, Maria Jesus, Panni, Simona, Duesbury, Margaret, Vallet, Sylvain D, Rappsilber, Juri, Ricard-Blum, Sylvie, Cesareni, Gianni, Salwinski, Lukasz, Orchard, Sandra, Porras, Pablo, Panneerselvam, Kalpana, and Hermjakob, Henning

Subjects
Aetiology, 2.6 Resources and infrastructure (aetiology), Databases, Protein, Humans, Protein Interaction Mapping, Protein Interaction Maps, Software, Environmental Sciences, Biological Sciences, Information and Computing Sciences, Developmental Biology
Abstract

The IntAct molecular interaction database (https://www.ebi.ac.uk/intact) is a curated resource of molecular interactions, derived from the scientific literature and from direct data depositions. As of August 2021, IntAct provides more than one million binary interactions, curated by twelve global partners of the International Molecular Exchange consortium, for which the IntAct database provides a shared curation and dissemination platform. The IMEx curation policy has always emphasised a fine-grained data and curation model, aiming to capture the relevant experimental detail essential for the interpretation of the provided molecular interaction data. Here, we present recent curation focus and progress, as well as a completely redeveloped website which presents IntAct data in a much more user-friendly and detailed way.

Published
2022

20. The Minimum Information about a Molecular Interaction Causal Statement (MI2CAST)

Author

Touré, Vasundra, Vercruysse, Steven, Acencio, Marcio Luis, Lovering, Ruth C, Orchard, Sandra, Bradley, Glyn, Casals-Casas, Cristina, Chaouiya, Claudine, del-Toro, Noemi, Flobak, Åsmund, Gaudet, Pascale, Hermjakob, Henning, Hoyt, Charles Tapley, Licata, Luana, Lægreid, Astrid, Mungall, Christopher J, Niknejad, Anne, Panni, Simona, Perfetto, Livia, Porras, Pablo, Pratt, Dexter, Saez-Rodriguez, Julio, Thieffry, Denis, Thomas, Paul D, Türei, Dénes, and Kuiper, Martin

Subjects
Generic health relevance, Causality, Humans, Software, Mathematical Sciences, Biological Sciences, Information and Computing Sciences, Bioinformatics
Abstract

MotivationA large variety of molecular interactions occurs between biomolecular components in cells. When a molecular interaction results in a regulatory effect, exerted by one component onto a downstream component, a so-called 'causal interaction' takes place. Causal interactions constitute the building blocks in our understanding of larger regulatory networks in cells. These causal interactions and the biological processes they enable (e.g. gene regulation) need to be described with a careful appreciation of the underlying molecular reactions. A proper description of this information enables archiving, sharing and reuse by humans and for automated computational processing. Various representations of causal relationships between biological components are currently used in a variety of resources.ResultsHere, we propose a checklist that accommodates current representations, called the Minimum Information about a Molecular Interaction CAusal STatement (MI2CAST). This checklist defines both the required core information, as well as a comprehensive set of other contextual details valuable to the end user and relevant for reusing and reproducing causal molecular interaction information. The MI2CAST checklist can be used as reporting guidelines when annotating and curating causal statements, while fostering uniformity and interoperability of the data across resources.Availability and implementationThe checklist together with examples is accessible at https://github.com/MI2CAST/MI2CAST.Supplementary informationSupplementary data are available at Bioinformatics online.

Published
2021

21. Correction to: The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Dibas, Mahmoud, Ghozy, Sherief, Adeeb, Nimer, Diestro, Jose Danilo Bengzon, Phan, Kevin, Cuellar-Saenz, Hugo H., Sweid, Ahmad, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Saliou, Guillaume, Möhlenbruch, Markus, Regenhardt, Robert W., Vranic, Justin E., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer, Salehani, Arsalaan, Sporns, Peter, Jones, Jesse, Psychogios, Marios, Spears, Julian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Stapleton, Christopher J., Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Tjoumakaris, Stavropoula, Jared Knopman, Aziz-Sultan, Mohammad A., Limbucci, Nicola, Jabbour, Pascal, Cognard, Christophe, and Patel, Aman B.

Published
2023
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22. RNAcentral 2021: secondary structure integration, improved sequence search and new member databases

Author

Sweeney, Blake A, Petrov, Anton I, Ribas, Carlos E, Finn, Robert D, Bateman, Alex, Szymanski, Maciej, Karlowski, Wojciech M, Seemann, Stefan E, Gorodkin, Jan, Cannone, Jamie J, Gutell, Robin R, Kay, Simon, Marygold, Steven, dos Santos, Gil, Frankish, Adam, Mudge, Jonathan M, Barshir, Ruth, Fishilevich, Simon, Chan, Patricia P, Lowe, Todd M, Seal, Ruth, Bruford, Elspeth, Panni, Simona, Porras, Pablo, Karagkouni, Dimitra, Hatzigeorgiou, Artemis G, Ma, Lina, Zhang, Zhang, Volders, Pieter-Jan, Mestdagh, Pieter, Griffiths-Jones, Sam, Fromm, Bastian, Peterson, Kevin J, Kalvari, Ioanna, Nawrocki, Eric P, Petrov, Anton S, Weng, Shuai, Bouchard-Bourelle, Philia, Scott, Michelle, Lui, Lauren M, Hoksza, David, Lovering, Ruth C, Kramarz, Barbara, Mani, Prita, Ramachandran, Sridhar, and Weinberg, Zasha

Subjects
Biological Sciences, Bioinformatics and Computational Biology, 2.6 Resources and infrastructure (aetiology), Animals, Apicomplexa, Base Sequence, Betacoronavirus, Databases, Nucleic Acid, Fungi, Gene Ontology, Humans, Internet, Molecular Sequence Annotation, Nucleic Acid Conformation, RNA, Untranslated, Sequence Analysis, RNA, Software, RNAcentral Consortium, Environmental Sciences, Information and Computing Sciences, Developmental Biology, Biological sciences, Chemical sciences, Environmental sciences
Abstract

RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences that provides a single access point to 44 RNA resources and >18 million ncRNA sequences from a wide range of organisms and RNA types. RNAcentral now also includes secondary (2D) structure information for >13 million sequences, making RNAcentral the world's largest RNA 2D structure database. The 2D diagrams are displayed using R2DT, a new 2D structure visualization method that uses consistent, reproducible and recognizable layouts for related RNAs. The sequence similarity search has been updated with a faster interface featuring facets for filtering search results by RNA type, organism, source database or any keyword. This sequence search tool is available as a reusable web component, and has been integrated into several RNAcentral member databases, including Rfam, miRBase and snoDB. To allow for a more fine-grained assignment of RNA types and subtypes, all RNAcentral sequences have been annotated with Sequence Ontology terms. The RNAcentral database continues to grow and provide a central data resource for the RNA community. RNAcentral is freely available at https://rnacentral.org.

Published
2021

23. Clinical Impact and Predictors of Diffusion Weighted Imaging (DWI) Reversal in Stroke Patients with Diffusion Weighted Imaging Alberta Stroke Program Early CT Score 0–5 Treated by Thrombectomy: Diffusion Weighted Imaging Reversal in Large Volume Stroke

Author

Panni, Pietro, Lapergue, Bertrand, Maïer, Benjamin, Finitsis, Stephanos, Clarençon, Frédéric, Richard, Sébastien, Marnat, Gaultier, Bourcier, Romain, Sibon, Igor, Dargazanli, Cyril, Blanc, Raphaël, Consoli, Arturo, Eugène, François, Vannier, Stéphane, Spelle, Laurent, Denier, Christian, Boulanger, Marion, Gauberti, Maxime, Saleme, Suzana, Macian, Francisco, Rosso, Charlotte, Naggara, Olivier, Turc, Guillaume, Ozkul-Wermester, Ozlem, Papagiannaki, Chrisanthi, Albucher, Jean-François, Darcourt, Jean, Le Bras, Anthony, Evain, Sarah, Wolff, Valérie, Pop, Raoul, Timsit, Serge, Gentric, Jean-Christophe, Bourdain, Frédéric, Veunac, Louis, Arquizan, Caroline, and Gory, Benjamin

Published
2022
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30. Early management of patients with aneurysmal subarachnoid hemorrhage in a hospital with neurosurgical/neuroendovascular facilities: a consensus and clinical recommendations of the Italian Society of Anesthesia and Intensive Care (SIAARTI)–Part 1

Author

Picetti, Edoardo, Barbanera, Andrea, Bernucci, Claudio, Bertuccio, Alessandro, Bilotta, Federico, Boccardi, Edoardo Pietro, Cafiero, Tullio, Caricato, Anselmo, Castioni, Carlo Alberto, Cenzato, Marco, Chieregato, Arturo, Citerio, Giuseppe, Gritti, Paolo, Lanterna, Luigi, Menozzi, Roberto, Munari, Marina, Panni, Pietro, Rossi, Sandra, Stocchetti, Nino, Sturiale, Carmelo, Zoerle, Tommaso, Zona, Gianluigi, Rasulo, Frank, and Robba, Chiara

Published
2022
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33. Early management of patients with aneurysmal subarachnoid hemorrhage in a hospital with neurosurgical/neuroendovascular facilities: a consensus and clinical recommendations of the Italian Society of Anesthesia and Intensive Care (SIAARTI)—part 2

Author

Picetti, Edoardo, Barbanera, Andrea, Bernucci, Claudio, Bertuccio, Alessandro, Bilotta, Federico, Boccardi, Edoardo Pietro, Cafiero, Tullio, Caricato, Anselmo, Castioni, Carlo Alberto, Cenzato, Marco, Chieregato, Arturo, Citerio, Giuseppe, Gritti, Paolo, Lanterna, Luigi, Menozzi, Roberto, Munari, Marina, Panni, Pietro, Rossi, Sandra, Stocchetti, Nino, Sturiale, Carmelo, Zoerle, Tommaso, Zona, Gianluigi, Rasulo, Frank, and Robba, Chiara

Published
2022
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34. The prognostic value of the previous nephrectomy in pretreated metastatic renal cell carcinoma receiving immunotherapy: a sub-analysis of the Meet-URO 15 study

Author

Rebuzzi, Sara Elena, Signori, Alessio, Banna, Giuseppe Luigi, Gandini, Annalice, Fornarini, Giuseppe, Damassi, Alessandra, Maruzzo, Marco, De Giorgi, Ugo, Basso, Umberto, Chiellino, Silvia, Galli, Luca, Zucali, Paolo Andrea, Fantinel, Emanuela, Naglieri, Emanuele, Procopio, Giuseppe, Milella, Michele, Boccardo, Francesco, Fratino, Lucia, Pipitone, Stefania, Ricotta, Riccardo, Panni, Stefano, Mollica, Veronica, Sorarù, Mariella, Santoni, Matteo, Cortellini, Alessio, Prati, Veronica, Soto Parra, Hector Josè, Santini, Daniele, Atzori, Francesco, Di Napoli, Marilena, Caffo, Orazio, Messina, Marco, Morelli, Franco, Prati, Giuseppe, Nolè, Franco, Vignani, Francesca, Cavo, Alessia, Roviello, Giandomenico, Rescigno, Pasquale, and Buti, Sebastiano

Published
2022
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35. Neutrophils predominate the immune signature of cerebral thrombi in COVID-19 stroke patients

Author

Genchi, Angela, Semerano, Aurora, Schwarz, Ghil, Dell’Acqua, Beatrice, Gullotta, Giorgia Serena, Sampaolo, Michela, Boeri, Enzo, Quattrini, Angelo, Sanvito, Francesca, Diamanti, Susanna, Bergamaschi, Andrea, Grassi, Stefano, Podini, Paola, Panni, Pietro, Michelozzi, Caterina, Simionato, Franco, Scomazzoni, Francesco, Remida, Paolo, Valvassori, Luca, Falini, Andrea, Ferrarese, Carlo, Michel, Patrik, Saliou, Guillaume, Hajdu, Steven, Beretta, Simone, Roveri, Luisa, Filippi, Massimo, Strambo, Davide, Martino, Gianvito, and Bacigaluppi, Marco

Published
2022
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38. The impact of postoperative aspirin in patients undergoing Woven EndoBridge: a multicenter, institutional, propensity score-matched analysis

Author

Dmytriw, Adam A, Musmar, Basel, Salim, Hamza, Aslan, Assala, Cancelliere, Nicole M, McLellan, Rachel M, Algin, Oktay, Ghozy, Sherief, Dibas, Mahmoud, Lay, Sovann V, Guenego, Adrien, Renieri, Leonardo, Carnevale, Joseph Anthony, Saliou, Guillaume, Mastorakos, Panagiotis, El Naamani, Kareem, Shotar, Eimad, Premat, Kevin, Mo¨hlenbruch, Markus A, Kral, Michael, Doron, Omer, Chung, Charlotte, Salem, Mohamed M, Lylyk, Ivan, Foreman, Paul M, Vachhani, Jay A, Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad Ubaid, Catapano, Joshua S, Waqas, Muhammad, Tutino, Vincent M, Ibrahim, Mohamed K, Mohammed, Marwa A, Imamoglu, Cetin, Bayrak, Ahmet, Rabinov, James D, Ren, Yifan, Schirmer, Clemens M, Piano, Mariangela, Kuhn, Anna Luisa, Michelozzi, Caterina, Elens, Stephanie, Hasan, Zuha, Starke, Robert M, Hassan, Ameer E, Ogilvie, Mark, Nguyen, Anh, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie Teresa, Psychogios, Marios-Nikos, Ulfert, Christian, Diestro, Jose Danilo Bengzon, Pukenas, Bryan, Burkhardt, Jan Karl, Huynh, Thien J, Martinez-Gutierrez, Juan Carlos, Essibayi, Muhammed Amir, Sheth, Sunil A, Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit S, Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberpfalzer, Monika, Griessenauer, Christoph J, Asadi, Hamed, Siddiqui, Adnan H, Brook, Allan L, Altschul, David, Ducruet, Andrew F, Albuquerque, Felipe C, Regenhardt, Robert W, Stapleton, Christopher J, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth Reddy, Knopman, Jared, Aziz-Sultan, Mohammad A, Tjoumakaris, Stavropoula I, Clarencon, Frédéric, Limbucci, Nicola, Cuellar, Hugo H, Jabbour, Pascal M, Pereira, Vitor M, Patel, Aman B, and Adeeb, Nimer

Abstract

BackgroundThe Woven EndoBridge (WEB) device is frequently used for the treatment of intracranial aneurysms. Postoperative management, including the use of aspirin, varies among clinicians and institutions, but its impact on the outcomes of the WEB has not been thoroughly investigated.MethodsThis was a retrospective, multicenter study involving 30 academic institutions in North America, South America, and Europe. Data from 1492 patients treated with the WEB device were included. Patients were categorized into two groups based on their postoperative use of aspirin (aspirin group: n=1124, non-aspirin group: n=368). Data points included patient demographics, aneurysm characteristics, procedural details, complications, and angiographic and functional outcomes. Propensity score matching (PSM) was applied to balance variables between the two groups.ResultsPrior to PSM, the aspirin group exhibited significantly higher rates of modified Rankin scale (mRS) mRS 0–1 and mRS 0–2 (89.8% vs 73.4% and 94.1% vs 79.8%, p<0.001), lower rates of mortality (1.6% vs 8.6%, p<0.001), and higher major compaction rates (13.4% vs 7%, p<0.001). Post-PSM, the aspirin group showed significantly higher rates of retreatment (p=0.026) and major compaction (p=0.037) while maintaining its higher rates of good functional outcomes and lower mortality rates. In the multivariable regression, aspirin was associated with higher rates of mRS 0–1 (OR 2.166; 95% CI 1.16 to 4, p=0.016) and mRS 0–2 (OR 2.817; 95% CI 1.36 to 5.88, p=0.005) and lower rates of mortality (OR 0.228; 95% CI 0.06 to 0.83, p=0.025). However, it was associated with higher rates of retreatment (OR 2.471; 95% CI 1.11 to 5.51, p=0.027).ConclusionsAspirin use post-WEB treatment may lead to better functional outcomes and lower mortality but with higher retreatment rates. These insights are crucial for postoperative management after WEB procedures, but further studies are necessary for validation.

Published
2025
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41. Correction to: “Recommendations for periprosthetic joint infections (PJI) prevention: the European Knee Associates (EKA)–International Committee American Association of Hip and Knee Surgeons (AAHKS)–Arthroplasty Society in Asia (ASIA) survey of members”

Author

Indelli, Pier Francesco, Iannotti, F., Ferretti, A., Valtanen, R., Prati, P., Pérez Prieto, D., Kort, N. P., Violante, B., Tandogan, N. R., Schiavone Panni, A., Pipino, G., and Hirschmann, M. T.

Published
2022
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45. Impact of flow and angioarchitecture on brain arteriovenous malformation outcome after gamma knife radiosurgery: the role of hemodynamics and morphology in obliteration

Author

Panni, Pietro, Gallotti, Alberto Luigi, Gigliotti, Carmen Rosaria, Shehata, Ahmed Badry, Albano, Luigi, da Passano, Camillo Ferrari, Barzaghi, Raffaella Lina Alessandra, Capitanio, Jody Filippo, Righi, Claudio, Simionato, Franco, Scomazzoni, Francesco, del Vecchio, Antonella, Falini, Andrea, and Mortini, Pietro

Published
2020
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