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29 results on '"Panesar, Balpreet"'

2. Primary outcome reporting in clinical trials for older adults with depression

Author

Rodrigues, Myanca, primary, Oprea, Anna, additional, Johnson, Keily, additional, Dufort, Alexander, additional, Sanger, Nitika, additional, Ghiassi, Pegah, additional, Sanger, Stephanie, additional, Panesar, Balpreet, additional, D'Elia, Alessia, additional, Parpia, Sameer, additional, Samaan, Zainab, additional, and Thabane, Lehana, additional

Published
2024
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4. Sex-Specific Risk Factors and Health Disparity Among Hepatitis C Positive Patients Receiving Pharmacotherapy for Opioid Use Disorder: Findings From a Propensity Matched Analysis

Author

Dennis, Brittany B., Martin, Leslie J., Naji, Leen, Akhtar, Daud, Cholankeril, George, Kim, Donghee, Sanger, Nitika, Hillmer, Alannah, Chawar, Caroul, D’Elia, Alessia, Panesar, Balpreet, Worster, Andrew, Marsh, David C., O’Shea, Tim, Bawor, Monica, Thabane, Lehana, Samaan, Zainab, and Ahmed, Aijaz

Published
2022
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12. The Inclusion of Patients’ Reported Outcomes to Inform Treatment Effectiveness Measures in Opioid Use Disorder. A Systematic Review

Author

Sanger,Nitika, Panesar,Balpreet, Dennis,Michael, Rosic,Tea, Rodrigues,Myanca, Lovell,Elizabeth, Yang,Shuling, Butt,Mehreen, Thabane,Lehana, and Samaan,Zainab

Subjects
Patient Related Outcome Measures
Abstract

Nitika Sanger,1,* Balpreet Panesar,2,* Michael Dennis,3 Tea Rosic,4 Myanca Rodrigues,4 Elizabeth Lovell,5 Shuling Yang,3 Mehreen Butt,6 Lehana Thabane,4,7 Zainab Samaan4,5 1Medical Science Graduate Program, McMaster University, Hamilton, Ontario, Canada; 2Neuroscience Graduate Program, McMaster University, Hamilton, Ontario, Canada; 3Michael G DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada; 4Health Research Methodology Graduate Program, McMaster University, Hamilton, Ontario, Canada; 5Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada; 6Accelerated Nursing Program, McMaster University, Hamilton, Ontario, Canada; 7Centre for Evaluation of Medicines, Programs for Assessment of Technology in Health (PATH) Research Institute, McMaster University, Hamilton, Ontario, Canada*These authors contributed equally to this workCorrespondence: Zainab Samaan, Health Research Methodology Graduate Program, McMaster University, Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main St. West, Hamilton, Ontario, Canada, Tel +1 905-522-1155 ext. 35448, Fax +1 905-381-5629, Email samaanz@mcmaster.caIntroduction: Patient centred care is needed now more than ever in the treatment of opioid use disorder. Trials, policy makers, and service providers have most often used treatment retention and opioid urine screens as measures of treatment effectiveness. However, patients receiving medication for opioid use disorder treatment (MOUD) may prioritise the use of different ways to assess treatment success.Objective: The aim of this review is to synthesize literature examining the self-reported goals patients would like to achieve in MOUD for opioid use disorder.Methods: We searched MEDLINE, EMBASE, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, Web of Science, Cochrane Library, Cochrane Clinical Trials Registry, the National Institutes for Health Clinical Trials Registry, and the WHO International Clinical Trials Registry Platform from inception until April 30th, 2021. No restrictions were placed on language, age, or type of MOUD. A qualitative synthesis is presented given that a meta-analysis was not possible.Results: The search yielded a total of 21,082 records from which 8 met criteria for inclusion in the qualitative synthesis. We identified a total of 43 patient-reported treatment goals from the 8 studies. Twelve domains were created from the 43 goals reported. These domains cover a range of important areas for patients’ goals related to living a normal life, physical health, mental health, treatment, and substance use specific areas.Conclusion: This review highlights several patient goals that they would like to achieve during treatment for opioid use disorder that are not commonly considered as markers of treatment effectiveness. Goals related to health, living a normal life, and overall substance use concerns by patients should be taken into consideration by clinical trialists, researchers, policy makers, service providers, patients, and communities engaged in developing and tailoring treatment plans for opioid use disorder.Systematic Review Registration: PROSPERO CRD42018095553.Keywords: opioid use disorder, patient reported outcomes, patient-centred care, medication for opioid use disorder

Published
2022

13. National suicide management guidelines recommending family-based prevention, intervention and postvention and their association with suicide mortality rates: systematic review

Author

Panesar, Balpreet, primary, Soni, Divya, additional, Khan, Mohammed I., additional, Bdair, Faris, additional, Holek, Matthew, additional, Tahir, Talha, additional, Woo, Julia, additional, Sanger, Nitika, additional, Khumalo, Nonhlanhla P., additional, Minuzzi, Luciano, additional, Thabane, Lehana, additional, and Samaan, Zainab, additional

Published
2022
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15. Sex-Specific Risk Factors and Health Disparity Among Hepatitis C Positive Patients Receiving Pharmacotherapy for Opioid Use Disorder: Findings From a Propensity Matched Analysis

Author

Dennis, Brittany B., primary, Martin, Leslie J., additional, Naji, Leen, additional, Akhtar, Daud, additional, Cholankeril, George, additional, Kim, Donghee, additional, Sanger, Nitika, additional, Hillmer, Alannah, additional, Chawar, Caroul, additional, D’Elia, Alessia, additional, Panesar, Balpreet, additional, Worster, Andrew, additional, Marsh, David C., additional, O’Shea, Tim, additional, Bawor, Monica, additional, Thabane, Lehana, additional, Samaan, Zainab, additional, and Ahmed, Aijaz, additional

Published
2021
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19. Additional file 1 of Delirium and other neuropsychiatric manifestations of COVID-19 infection in people with preexisting psychiatric disorders: a systematic review

Author

van Reekum, Emma A., Rosic, Tea, Sergeant, Anjali, Sanger, Nitika, Rodrigues, Myanca, Rebinsky, Reid, Panesar, Balpreet, Deck, Eve, Kim, Nayeon, Woo, Julia, D���Elia, Alessia, Hillmer, Alannah, Dufort, Alexander, Sanger, Stephanie, Thabane, Lehana, Mbuagbaw, Lawrence, and Samaan, Zainab

Abstract

Additional file 1. Table S1. PRISMA Research Checklist.

Published
2021
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20. Additional file 2 of Delirium and other neuropsychiatric manifestations of COVID-19 infection in people with preexisting psychiatric disorders: a systematic review

Author

van Reekum, Emma A., Rosic, Tea, Sergeant, Anjali, Sanger, Nitika, Rodrigues, Myanca, Rebinsky, Reid, Panesar, Balpreet, Deck, Eve, Kim, Nayeon, Woo, Julia, D���Elia, Alessia, Hillmer, Alannah, Dufort, Alexander, Sanger, Stephanie, Thabane, Lehana, Mbuagbaw, Lawrence, and Samaan, Zainab

Subjects
Data_FILES
Abstract

Additional file 2. Table S2. Search Strategy.

Published
2021
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21. The future of precision medicine in opioid use disorder: inclusion of patient-important outcomes in clinical trials

Author

Sanger, Nitika, primary, Panesar, Balpreet, additional, Rosic, Tea, additional, Dennis, Brittany, additional, D'Elia, Alessia, additional, Hillmer, Alannah, additional, Chawar, Caroul, additional, Naji, Leen, additional, Hudson, Jacqueline, additional, Samaan, M. Constantine, additional, de Souza, Russell J., additional, Marsh, David C., additional, Thabane, Lehana, additional, and Samaan, Zainab, additional

Published
2021
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22. Are patients’ goals in treatment associated with expected treatment outcomes? Findings from a mixed-methods study on outpatient pharmacological treatment for opioid use disorder

Author

Rosic, Tea, primary, Naji, Leen, additional, Panesar, Balpreet, additional, Chai, Darren B, additional, Sanger, Nitika, additional, Dennis, Brittany B, additional, Marsh, David C, additional, Rieb, Launette, additional, Worster, Andrew, additional, Thabane, Lehana, additional, and Samaan, Zainab, additional

Published
2021
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23. Treatment Outcomes in Patients With Opioid Use Disorder Who Were First Introduced to Opioids by Prescription: A Systematic Review and Meta-Analysis

Author

Sanger, Nitika, primary, Bhatt, Meha, additional, Singhal, Nikhita, additional, Panesar, Balpreet, additional, D’Elia, Alessia, additional, Trottier, Maegan, additional, Shahid, Hamnah, additional, Hillmer, Alannah, additional, Baptist-Mohseni, Natasha, additional, Roczyki, Victoria, additional, Soni, Divya, additional, Brush, Maurana, additional, Lovell, Elizabeth, additional, Sanger, Stephanie, additional, Samaan, M. Constantine, additional, de Souza, Russell J., additional, Thabane, Lehana, additional, and Samaan, Zainab, additional

Published
2020
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29. The future of precision medicine in opioid use disorder: inclusion of patient-important outcomes in clinical trials.

Author

Sanger N, Panesar B, Rosic T, Dennis B, D'Elia A, Hillmer A, Chawar C, Naji L, Hudson J, Samaan MC, de Souza RJ, Marsh DC, Thabane L, and Samaan Z

Subjects
Adult, Analgesics, Opioid adverse effects, Female, Humans, Male, Opiate Substitution Treatment, Precision Medicine, United States, Behavior, Addictive, Opioid-Related Disorders drug therapy
Abstract

Opioid use has reached an epidemic proportion in Canada and the United States that is mostly attributed to excess availability of prescribed opioids for pain. This excess in opioid use led to an increase in the prevalence of opioid use disorder (OUD) requiring treatment. The most common treatment recommendations include medication-assisted treatment (MAT) combined with psychosocial interventions. Clinical trials investigating the effectiveness of MAT, however, have a limited focus on effectiveness measures that overlook patient-important outcomes. Despite MAT, patients with OUD continue to suffer negative consequences of opioid use. Patient goals and personalized medicine are overlooked in clinical trials and guidelines, thus missing an opportunity to improve prognosis of OUD by considering precision medicine in addiction trials. In this mixed-methods study, patients with OUD receiving MAT (n=2,031, mean age 39.1 years [SD 10.7], 44% female) were interviewed to identify patient goals for MAT. The most frequently reported patient-important outcomes were to stop treatment (39%) and to avoid all drugs (25%). These results are inconsistent with treatment recommendations and trial outcome measures. We discuss theses inconsistencies and make recommendations to incorporate these outcomes to achieve patient-centered and personalized treatment strategies.

Published
2021
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