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1. Residential radon and characteristics of chronic obstructive pulmonary disease

Author: Pando-Sandoval, Ana, Ruano-Ravina, Alberto, Torres-Durán, María, Dacal-Quintas, Raquel, Valdés-Cuadrado, Luis, Hernández-Hernández, Jesús R., Consuegra-Vanegas, Angélica, Candal-Pedreira, Cristina, Varela-Lema, Leonor, Fernández-Villar, Alberto, and Pérez-Ríos, Mónica
Published: 2022
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2. Indoor Radon Exposure and COPD, Synergic Association? A Multicentric, Hospital-Based Case–Control Study in a Radon-Prone Area

Author: Ruano-Ravina, Alberto, Cameselle-Lago, Candela, Torres-Durán, María, Pando-Sandoval, Ana, Dacal-Quintas, Raquel, Valdés-Cuadrado, Luis, Hernández-Hernández, Jesús, Consuegra-Vanegas, Angélica, Tenes-Mayén, José Andrés, Varela-Lema, Leonor, Fernández-Villar, Alberto, Barros-Dios, Juan Miguel, and Pérez-Ríos, Mónica
Published: 2021
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3. An international perspective on hospitalized patients with viral community-acquired pneumonia

Author: Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I., Cambursano, Victor Hugo, Ceccato, Adrian, Chertcoff, Julio, Cordon Díaz, Ariel, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M., Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Anseeuw, Kurt, Francois, Camille A., Van Braeckel, Eva, Vincent, Jean Louis, Djimon, Marcel Zannou, Aranha Nouér, Simone, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Balkissou, Adamou Dodo, Pefura Yone, Eric Walter, Mbatchou Ngahane, Bertrand Hugo, Shen, Ning, Xu, Jin-fu, Bustamante Rico, Carlos Andres, Buitrago, Ricardo, Pereira Paternina, Fernando Jose, Kayembe Ntumba, Jean-Marie, Vladic-Carevic, Vesna, Jakopovic, Marko, Matkovic, Zinka, Mitrecic, Ivan, Bouchy Jacobsson, Marie-Laure, Bro Christensen, Anette, Bødtger, Uffe, Meyer, Christian Niels, Vestergaard Jensen, Andreas, El-Said Abd El-Wahhab, Ibrahim, Elsayed Morsy, Nesreen, Shafiek, Hanaa, Sobh, Eman, Abdulsemed, Kedir Abdella, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Pletz, Mathias W., Hagel, Stefan, Rupp, Jan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Dimakou, Katerina, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Kaimakamis, Evangelos, Bhatia, Mohit, Dhar, Raja, D’Souza, George, Garg, Rajiv, Koul, Parvaiz A., Jayaraj, B.S., Narayan, Kiran Vishnu, Udnur, Hirennappa B., Krishnamurthy, Shashi Bhaskara, Kant, Surya, Swarnakar, Rajesh, Salvi, Sundeep, Limaye, Sneha, Golshani, Keihan, Keatings, Vera M., Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, d’Arminio Monforte, Antonella, Del Prato, Bruno, De Rosa, Marino, Fantini, Riccardo, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Petrino, Roberta, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, Franzetti, Fabio, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Aoun Bacha, Zeina, Barajas Ugalde, Daniel, Ceballos Zuñiga, Omar, Villegas, José F., Medenica, Milic, van de Garde, E.M.W., Raj Mihsra, Deebya, Shrestha, Poojan, Ridgeon, Elliott, Ishola Awokola, Babatunde, Nwankwo, Ogonna N.O., Olufunlola, Adefuye Bolanle, Olumide, Segaolu, Ukwaja, Kingsley N., Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczyński, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Ravara, Sofia B., Brocovschii, Victoria, Ion, Chesov, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Dorobat, Carmen Mihaela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Bukhary, Zakeya Abdulbaqi Ali, Edathodu, Jameela, Fathy, Amal, Mushira Abdulaziz Enani, Abdullah, Eltayeb Mohamed, Nazik, Ulhadi Memon, Jawed, Bella, Abdelhaleem, Bogdanović, Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Bordon Garcia, Noel Manuel, Cabello Alarcón, Hugo, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, Encabo González, Alicia, Fernández-Almira, Maria Luisa, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, González Del Castillo, Juan, Javaloyes Victoria, Patricia, Laserna Martínez, Elena, Malo de Molina, Rosa, Menéndez, Rosario, Pando-Sandoval, Ana, Prat Aymerich, Cristina, Lacoma de la Torre, Alicia, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Sanz, Francisco, Sibila, Oriol, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, van Boven, Job F.M., Vendrell Torra, Ester, Pujol, Jordi Almirall, Feldman, Charles, Kee Yum, Ho, Fiogbe, Arnauld Attannon, Yangui, Ferdaous, Bilaceroglu, Semra, Dalar, Levent, Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J., Feneley, Andrew, Hancock, Carole, Hill, Adam T., Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Allen, Karen S., Brito, Veronica, Dietz, Jessica, Dysart, Claire E., Kellie, Susan M., Franco-Sadud, Ricardo A., Meier, Garnet, Gaga, Mina, Holland, Thomas L., Bergin, Stephen P., Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B., Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Soni, Nilam J., Noda, Julio, Hinojosa, Cecilia I., Levine, Stephanie M., Angel, Luis F., Anzueto, Antonio, Scott Whitlow, K., Hipskind, John, Sukhija, Kunal, Totten, Vicken, Wunderink, Richard G., Shah, Ray D., Mateyo, Kondwelani John, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Radovanovic, Dejan, Sotgiu, Giovanni, Jankovic, Mateja, Mahesh, Padukudru Anand, Marcos, Pedro Jorge, Abdalla, Mohamed I., Di Pasquale, Marta Francesca, Gramegna, Andrea, Terraneo, Silvia, Blasi, Francesco, Santus, Pierachille, Aliberti, Stefano, Reyes, Luis F., and Restrepo, Marcos I.
Published: 2019
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4. Residual pulmonary infiltrates, symptoms and diffusion impairment at one‐year after severe COVID‐19 infection have different associated factors

Author: Menéndez, Rosario, primary, Méndez, Raúl, additional, Latorre, Ana, additional, González‐Jiménez, Paula, additional, Peces‐Barba, Germán, additional, Molina, María, additional, España, Pedro Pablo, additional, García, Estela, additional, Consuegra‐Vanegas, Angélica, additional, Pando‐Sandoval, Ana, additional, Panadero, Carolina, additional, Figueira‐Gonçalves, Juan Marco, additional, De la Rosa, David, additional, Sibila, Oriol, additional, Martínez‐Pitarch, María Dolores, additional, Toledo, Nuria, additional, Cejudo, Pilar, additional, Almonte‐Batista, Wanda, additional, Macías‐Paredes, Abigail, additional, Badenes, Diana, additional, Pérez‐Rodas, Eli Nancy, additional, Lázaro, Javier, additional, Quirós, Sarai, additional, Cordovilla, Rosa, additional, Cano‐Pumarega, Irene, additional, and Torres, Antoni, additional
Published: 2023
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5. Global initiative for meticillin-resistant Staphylococcus aureus pneumonia (GLIMP): an international, observational cohort study

Author: Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I, Cambursano, Victor Hugo, Ceccato, Adrian, Chertcoff, Julio, Lascar, Florencia, Di Tulio, Fernando, Cordon Díaz, Ariel, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M, Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Vincent, Jean Louis, Anseeuw, Kurt, Francois, Camille A, Van Braeckel, Eva, Djimon, Marcel Zannou, Bashi, Jules, Dodo, Roger, Aranha Nouér, Simone, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Balkissou, Adamou Dodo, Pefura Yone, Eric Walter, Mbatchou Ngahane, Bertrand Hugo, Shen, Ning, Xu, Jin-fu, Bustamante Rico, Carlos Andres, Buitrago, Ricardo, Pereira Paternina, Fernando Jose, Kayembe Ntumba, Jean-Marie, Vladic Carevic, Vesna, Jakopovic, Marko, Jankovic, Mateja, Matkovic, Zinka, Mitrecic, Ivan, Bouchy Jacobsson, Marie-Laure, Bro Christensen, Anette, Heitmann Bødtger, Uffe Christian, Meyer, Christian Niels, Vestergaard Jensen, Andreas, Baunbæk-knudsen, Gertrud, Trier Petersen, Pelle, Andersen, Stine, El-Said Abd El-Wahhab, Ibrahim, Elsayed Morsy, Nesreen, Shafiek, Hanaa, Sobh, Eman, Abdulsemed, Kedir Abdella, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Pletz, Mathias W, Hagel, Stefan, Rupp, Jan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Dimakou, Katerina, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Kaimakamis, Evangelos, Bhatia, Mohit, Dhar, Raja, D'Souza, George, Garg, Rajiv, Koul, Parvaiz A, Mahesh, P A, Jayaraj, B S, Narayan, Kiran Vishnu, Udnur, Hirennappa B, Krishnamurthy, Shashi Bhaskara, Kant, Surya, Swarnakar, Rajesh, Limaye, Sneha, Salvi, Sundeep, Golshani, Keihan, Keatings, Vera M, Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, d'Arminio Monforte, Antonella, Del Prato, Bruno, De Rosa, Marino, Fantini, Riccardo, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Petrino, Roberta, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, Franzetti, Fabio, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Aoun Bacha, Zeina, Barajas Ugalde, Daniel, Ceballos Zuñiga, Omar, Villegas, José F, Medenica, Milic, van de Garde, E M W, Raj Mihsra, Deebya, Shrestha, Poojan, Ridgeon, Elliott, Ishola Awokola, Babatunde, Nwankwo, Ogonna N O, Olufunlola, Adefuye Bolanle, Olumide, Segaolu, Ukwaja, Kingsley N, Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczynski, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Ravara, Sofia B, Brocovschii, Victoria, Ion, Chesov, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Dorobat, Carmen Mihaela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Bukhary, Zakeya Abdulbaqi Ali, Edathodu, Jameela, Fathy, Amal, Mushira Abdulaziz Enani, Abdullah, Eltayeb Mohamed, Nazik, Ulhadi Memon, Jawed, Bella, Abdelhaleem, Bogdanovic, Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Bordon Garcia, Noel Manuel, Cabello Alarcón, Hugo, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, Encabo González, Alicia, Fernández-Almira, Maria Luisa, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, González del Castillo, Juan, Javaloyes Victoria, Patricia, Laserna Martínez, Elena, Malo de Molina, Rosa, Marcos, Pedro J, Menéndez, Rosario, Pando-Sandoval, Ana, Prat Aymerich, Cristina, Lacoma de la Torre, Alicia, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Sanz, Francisco, Sibila, Oriol, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, van Boven, Job FM, Vendrell Torra, Ester, Pujol, Jordi Almirall, Feldman, Charles, Kee Yum, Ho, Fiogbe, Arnauld Attannon, Yangui, Ferdaous, Bilaceroglu, Semra, Dalar, Levent, Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J, Feneley, Andrew, Ions, Rhiannon, Skeemer, Julie, Woltmann, Gerrit, Hancock, Carole, Hill, Adam T, Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Allen, Karen S, Brito, Veronica, Dietz, Jessica, Dysart, Claire E, Kellie, Susan M, Franco-Sadud, Ricardo A, Meier, Garnet, Gaga, Mina, Holland, Thomas L, Bergin, Stephen P, Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B, Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Soni, Nilam J, Noda, Julio, Hinojosa, Cecilia I, Levine, Stephanie M, Angel, Luis F, Anzueto, Antonio, Whitlow, K Scott, Hipskind, John, Sukhija, Kunal, Totten, Vicken, Wunderink, Richard G, Shah, Ray D, Mateyo, Kondwelani John, Noriega, Lorena, Alvarado, Ezequiel, Aman, Mohamed, Labra, Lucía, Aliberti, Stefano, Reyes, Luis F, Faverio, Paola, Sotgiu, Giovanni, Dore, Simone, Rodriguez, Alejandro H, and Restrepo, Marcos I
Published: 2016
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6. Residual pulmonary infiltrates, symptoms and diffusion impairment at 1‐year after severe COVID‐19 infection have different associated factors.

Author: Menéndez, Rosario, Méndez, Raúl, Latorre, Ana, González‐Jiménez, Paula, Peces‐Barba, Germán, Molina, María, España, Pedro Pablo, García, Estela, Consuegra‐Vanegas, Angélica, Pando‐Sandoval, Ana, Panadero, Carolina, Figueira‐Gonçalves, Juan Marco, De la Rosa, David, Sibila, Oriol, Martínez‐Pitarch, María Dolores, Toledo, Nuria, Cejudo, Pilar, Almonte‐Batista, Wanda, Macías‐Paredes, Abigail, and Badenes, Diana
Subjects: SARS-CoV-2, COVID-19, SMOKING, ASYMPTOMATIC patients
Abstract: Introduction: After severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pneumonia, patients may show lung sequelae on radiology and functional impairment at the 1‐year follow‐up. We aimed to describe the persistence of symptoms, radiological alterations, or reduced diffusing capacity of the lung for carbon monoxide (DLCO) at 1‐year follow‐up in patients from the Spanish Registry RECOVID. Methods: RECOVID collected symptom and radiological and functional lung tests data on hospitalized patients with coronavirus disease 2019 during the acute phase and at the 6‐ and 12‐month follow‐up visits. Results: Of the 2500 enrolled survivors (90% admitted to the ward), 1874 had follow‐up visits for up to a year. Of these, 42% continued to present with symptoms, 27% had radiological sequelae and 31% had reduced DLCO. Independently associated factors included female sex, asthma and the requirement for invasive or non‐invasive mechanical ventilation. Complete radiological resolution was 72.2% at 12 months; associated factors with incomplete recovery were age, male sex, oxygen or respiratory support, corticosteroids and an initial SpO2/FiO2 <450 or CURB‐65 ≥2. Reduced DLCO was observed in 31% of patients at 12 months; associated factors were older age, female sex, smoking habit, SpO2/FiO2 <450 and CURB‐65 ≥2 and the requirement of respiratory support.At 12 months, a proportion of the asymptomatic patients showed reduced DLCO (9.5%), radiological findings (25%) or both (11%). Conclusions: The factors associated with symptom persistence, incomplete radiological resolution and DLCO <80% differed according to age, sex, comorbidities and respiratory support. The burden of symptoms, reduced DLCO and incomplete radiological resolution were considerable in patients with SARS‐CoV‐2 pneumonia at the 1‐year follow‐up after hospitalisation. [ABSTRACT FROM AUTHOR]
Published: 2023
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7. Residential radon and characteristics of chronic obstructive pulmonary disease

Author: Universidade de Santiago de Compostela. Departamento de Psiquiatría, Radioloxía, Saúde Pública, Enfermaría e Medicina, Pando Sandoval, Ana, Ruano Raviña, Alberto, Torres Durán, María, Dacal Quintas, Raquel, Valdés Cuadrado, Luis Guillermo, Hernández Hernández, Jesús R., Consuegra Vanegas, Angélica, Candal Pedreira, Cristina, Varela Lema, María Leonor, Fernández Villar, Alberto, Pérez Ríos, Mónica, Universidade de Santiago de Compostela. Departamento de Psiquiatría, Radioloxía, Saúde Pública, Enfermaría e Medicina, Pando Sandoval, Ana, Ruano Raviña, Alberto, Torres Durán, María, Dacal Quintas, Raquel, Valdés Cuadrado, Luis Guillermo, Hernández Hernández, Jesús R., Consuegra Vanegas, Angélica, Candal Pedreira, Cristina, Varela Lema, María Leonor, Fernández Villar, Alberto, and Pérez Ríos, Mónica
Abstract: It is not known whether residential radon exposure may be linked to the development of chronic obstructive pulmonary disease (COPD) and/or have an influence on the functional characteristics or exacerbations of COPD. The aim of this study was therefore to ascertain whether there might be an association between residential radon concentrations and certain characteristics of COPD. We analyzed COPD cases drawn from a case–control study conducted in an area of high radon exposure. Data were collected on spirometric pulmonary function variables, hospital admissions, and smoking. Radon measurements were taken using alpha-track-type CR-39 detectors individually placed in patients’ homes. All statistical analyses were performed using the IBM SPSS v22 computer software program. The study included 189 COPD cases (79.4% men; median age 64 years). The median radon concentration was 157 Bq/m3. No differences were found between radon concentration and sex, age or severity of breathing obstruction as measured by FEV1%. It should be noted, however, that 48.1% of patients with FEV1% < 50 had radon concentrations below 100 Bq/m3, as compared to 35.6% with the same severity of obstruction who had over 300 Bq/m3. COPD cases with radon concentrations higher than > 600 Bq/m3 exhibited no different characteristics in lung function. Exposure to radon does not appear to have an influence on the clinical characteristics of smokers and ex-smokers with COPD. As exposure to residential radon increases, there is no trend towards a worsening of FEV1%. Further studies are thus needed to analyze this possible association in never-smokers with COPD
Published: 2022

8. Risk factors for chronic obstructive pulmonary disease in never‐smokers: A systematic review

Author: Pando‐Sandoval, Ana, primary, Ruano‐Ravina, Alberto, additional, Candal‐Pedreira, Cristina, additional, Rodríguez‐García, Carlota, additional, Represas‐Represas, Cristina, additional, Golpe, Rafael, additional, Fernández‐Villar, Alberto, additional, and Pérez‐Ríos, Mónica, additional
Published: 2022
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9. Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients

Author: Di Pasquale, Marta Francesca, Sotgiu, Giovanni, Gramegna, Andrea, Radovanovic, Dejan, Terraneo, Silvia, Reyes, Luis F, Rupp, Jan, González del Castillo, Juan, Blasi, Francesco, Aliberti, Stefano, Restrepo, Marcos I, Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I, Cambursano, Victor Hugo, Cazaux, A, Ceccato, Adrian, Chertcoff, Julio, Lascar, Florencia, Tulio, Fernando Di, Díaz, Ariel Cordon, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M, Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Cetrangolo, Antonio A, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Anseeuw, Kurt, Francois, Camille A, Van Braeckel, Eva, Vincent, Jean Louis, Djimon, Marcel Zannou, Bashi, Jules, Dodo, Roger, Nouér, Simone Aranha, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Balkissou, Adamou Dodo, Yone, Eric Walter Pefura, Ngahane, Bertrand Hugo Mbatchou, Shen, Ning, Xu, Jin-fu, Rico, Carlos Andres Bustamante, Buitrago, Ricardo, Paternina, Fernando Jose Pereira, Ntumba, Jean-Marie Kayembe, Carevic, Vesna Vladic, Jakopovic, Marko, Jankovic, Mateja, Matkovic, Zinka, Mitrecic, Ivan, Jacobsson, Marie-Laure Bouchy, Christensen, Anette Bro, Bødtger, Uffe Christian Heitmann, Meyer, Christian Niels, Jensen, Andreas Vestergaard, Baunbæk-Knudsen, Gertrud, Petersen, Pelle Trier, Andersen, Stine, El-Wahhab, Ibrahim El-Said Abd, Morsy, Nesreen Elsayed, Shafiek, Hanaa, Sobh, Eman, Abdulsemed, Kedir Abdella, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Niederlausitz, Klinikum, Pletz, Mathias W, Hagel, Stefan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Dimakou, Katerina, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Kaimakamis, Evangelos, Bhatia, Mohit, Dhar, Raja, D’Souza, George, Garg, Rajiv, Koul, Parvaiz A, Mahesh, P A, Jayaraj, B S, Narayan, Kiran Vishnu, Udnur, Hirennappa B, Krishnamurthy, Shashi Bhaskara, Kant, Surya, Swarnakar, Rajesh, Limaye, Sneha, Salvi, Sundeep, Golshani, Keihan, Keatings, Vera M, Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, Monforte, Antonella d’Arminio, Prato, Bruno Del, Rosa, Marino De, Fantini, Riccardo, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Petrino, Roberta, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, Franzetti, Fabio, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Bacha, Zeina Aoun, Ugalde, Daniel Barajas, Zuñiga, Omar Ceballos, Villegas, José F, Medenica, Milic, van de Garde, E M W, Mihsra, Deebya Raj, Shrestha, Poojan, Ridgeon, Elliott, Awokola, Babatunde Ishola, Nwankwo, Ogonna N O, Olufunlola, Adefuye Bolanle, Olumide, Segaolu, Ukwaja, Kingsley N, Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczyński, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Ravara, Sofia B, Brocovschii, Victoria, Ion, Chesov, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Dorobat, Carmen Mihaela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Bukhary, Zakeya Abdulbaqi Ali, Edathodu, Jameela, Fathy, Amal, Enani, Abdullah Mushira Abdulaziz, Mohamed, Nazik Eltayeb, Memon, Jawed Ulhadi, Bella, Abdelhaleem, Bogdanović, Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Garcia, Noel Manuel Bordon, Alarcón, Hugo Cabello, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, González, Alicia Encabo, Fernández-Almira, Maria Luisa, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, del Castillo, Juan González, Victoria, Patricia Javaloyes, Martínez, Elena Laserna, de Molina, Rosa Malo, Marcos, Pedro J, Menéndez, Rosario, Pando-Sandoval, Ana, Aymerich, Cristina Prat, de la Torre, Alicia Lacoma, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Sanz, Francisco, Sibila, Oriol, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, van Boven, Job F M, Torra, Ester Vendrell, Pujol, Jordi Almirall, Feldman, Charles, Yum, Ho Kee, Fiogbe, Arnauld Attannon, Yangui, Ferdaous, Bilaceroglu, Semra, Dalar, Levent, Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J, Feneley, Andrew, Ions, Rhiannon, Skeemer, Julie, Woltmann, Gerrit, Hancock, Carole, Hill, Adam T, Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Allen, Karen S, Brito, Veronica, Dietz, Jessica, Dysart, Claire E, Kellie, Susan M, Franco-Sadud, Ricardo A, Meier, Garnet, Gaga, Mina, Holland, Thomas L, Bergin, Stephen P, Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B, Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Soni, Nilam J, Noda, Julio, Hinojosa, Cecilia I, Levine, Stephanie M, Angel, Luis F, Anzueto, Antonio, Whitlow, K Scott, Hipskind, John, Sukhija, Kunal, Totten, Vicken, Wunderink, Richard G, Shah, Ray D, Mateyo, Kondwelani John, Noriega, Lorena, Alvarado, Ezequiel, Aman, Mohamed, Labra, Lucía, Value, Affordability and Sustainability (VALUE), Groningen Research Institute for Asthma and COPD (GRIAC), Di Pasquale, M. F., Sotgiu, G., Gramegna, A., Radovanovic, D., Terraneo, S., Reyes, L. F., Rupp, J., Gonzalez Del Castillo, J., Blasi, F., Aliberti, S., Restrepo, M. I., Aruj, P. K., Attorri, S., Barimboim, E., Caeiro, J. P., Garzon, M. I., Cambursano, V. H., Cazaux, A., Ceccato, A., Chertcoff, J., Lascar, F., Tulio, F. D., Diaz, A. C., de Vedia, L., Ganaha, M. C., Lambert, S., Lopardo, G., Luna, C. M., Malberti, A. G., Morcillo, N., Tartara, S., Cetrangolo, A. A., Pensotti, C., Pereyra, B., Scapellato, P. G., Stagnaro, J. P., Shah, S., Lotsch, F., Thalhammer, F., Anseeuw, K., Francois, C. A., Van Braeckel, E., Vincent, J. L., Djimon, M. Z., Bashi, J., Dodo, R., Nouer, S. A., Chipev, P., Encheva, M., Miteva, D., Petkova, D., Balkissou, A. D., Yone, E. W. P., Ngahane, B. H. M., Shen, N., Xu, J. F., Rico, C. A. B., Buitrago, R., Paternina, F. J. P., Ntumba, J. K., Carevic, V. V., Jakopovic, M., Jankovic, M., Matkovic, Z., Mitrecic, I., Jacobsson, M. B., Christensen, A. B., Bodtger, U. C. H., Meyer, C. N., Jensen, A. V., Baunbaek-Knudsen, G., Petersen, P. T., Andersen, S., El-Wahhab, I. E. A., Morsy, N. E., Shafiek, H., Sobh, E., Abdulsemed, K. A., Bertrand, F., Brun-Buisson, C., de Montmollin, E., Fartoukh, M., Messika, J., Tattevin, P., Khoury, A., Ebruke, B., Dreher, M., Kolditz, M., Meisinger, M., Niederlausitz, K., Pletz, M. W., Hagel, S., Schaberg, T., Spielmanns, M., Creutz, P., Suttorp, N., Siaw-Lartey, B., Dimakou, K., Papapetrou, D., Tsigou, E., Ampazis, D., Kaimakamis, E., Bhatia, M., Dhar, R., D'Souza, G., Garg, R., Koul, P. A., Mahesh, P. A., Jayaraj, B. S., Narayan, K. V., Udnur, H. B., Krishnamurthy, S. B., Kant, S., Swarnakar, R., Limaye, S., Salvi, S., Golshani, K., Keatings, V. M., Martin-Loeches, I., Maor, Y., Strahilevitz, J., Battaglia, S., Carrabba, M., Ceriana, P., Confalonieri, M., Monforte, A. D., Prato, B. D., Rosa, M., Fantini, R., Fiorentino, G., Gammino, M. A., Menzella, F., Milani, G., Nava, S., Palmiero, G., Petrino, R., Gabrielli, B., Rossi, P., Sorino, C., Steinhilber, G., Zanforlin, A., Franzetti, F., Carugati, M., Morosi, M., Monge, E., Carone, M., Patella, V., Scarlata, S., Comel, A., Kurahashi, K., Bacha, Z. A., Ugalde, D. B., Zuniga, O. C., Villegas, J. F., Medenica, M., van de Garde, E. M. W., Mihsra, D. R., Shrestha, P., Ridgeon, E., Awokola, B. I., Nwankwo, O. N. O., Olufunlola, A. B., Olumide, S., Ukwaja, K. N., Irfan, M., Minarowski, L., Szymon, S., Froes, F., Leuschner, P., Meireles, M., Ferrao, C., Neves, J., Ravara, S. B., Brocovschii, V., Ion, C., Rusu, D., Toma, C., Chirita, D., Dorobat, C. M., Birkun, A., Kaluzhenina, A., Almotairi, A., Bukhary, Z. A. A., Edathodu, J., Fathy, A., Enani, A. M. A., Mohamed, N. E., Memon, J. U., Bella, A., Bogdanovic, N., Milenkovic, B., Pesut, D., Borderias, L., Garcia, N. M. B., Alarcon, H. C., Cilloniz, C., Torres, A., Diaz-Brito, V., Casas, X., Gonzalez, A. E., Fernandez-Almira, Ml., Gallego, M., Gaspar-GarcIa, I., Victoria, P. J., Martinez, E. L., de Molina, R. M., Marcos, P. J., Menendez, R., Pando-Sandoval, A., Aymerich, C. P., de la Torre, A. L., Garcia-Olive, I., Rello, J., Moyano, S., Sanz, F., Sibila, O., Rodrigo-Troyano, A., Sole-Violan, J., Uranga, A., van Boven, J. F. M., Torra, E. V., Pujol, J. A., Feldman, C., Yum, H. K., Fiogbe, A. A., Yangui, F., Bilaceroglu, S., Dalar, L., Yilmaz, U., Bogomolov, A., Elahi, N., Dhasmana, D. J., Feneley, A., Ions, R., Skeemer, J., Woltmann, G., Hancock, C., Hill, A. T., Rudran, B., Ruiz-Buitrago, S., Campbell, M., Whitaker, P., Youzguin, A., Singanayagam, A., Allen, K. S., Brito, V., Dietz, J., Dysart, C. E., Kellie, S. M., Franco-Sadud, R. A., Meier, G., Gaga, M., Holland, T. L., Bergin, S. P., Kheir, F., Landmeier, M., Lois, M., Nair, G. B., Patel, H., Reyes, K., Rodriguez-Cintron, W., Saito, S., Soni, N. J., Noda, J., Hinojosa, C. I., Levine, S. M., Angel, L. F., Anzueto, A., Whitlow, K. S., Hipskind, J., Sukhija, K., Totten, V., Wunderink, R. G., Shah, R. D., Mateyo, K. J., Noriega, L., Alvarado, E., Aman, M., Labra, L., Di Pasquale M.F., Sotgiu G., Gramegna A., Radovanovic D., Terraneo S., Reyes L.F., Rupp J., Gonzalez Del Castillo J., Blasi F., Aliberti S., Restrepo M.I., Aruj P.K., Attorri S., Barimboim E., Caeiro J.P., Garzon M.I., Cambursano V.H., Cazaux A., Ceccato A., Chertcoff J., Lascar F., Tulio F.D., Diaz A.C., de Vedia L., Ganaha M.C., Lambert S., Lopardo G., Luna C.M., Malberti A.G., Morcillo N., Tartara S., Cetrangolo A.A., Pensotti C., Pereyra B., Scapellato P.G., Stagnaro J.P., Shah S., Lotsch F., Thalhammer F., Anseeuw K., Francois C.A., Van Braeckel E., Vincent J.L., Djimon M.Z., Bashi J., Dodo R., Nouer S.A., Chipev P., Encheva M., Miteva D., Petkova D., Balkissou A.D., Yone E.W.P., Ngahane B.H.M., Shen N., Xu J.F., Rico C.A.B., Buitrago R., Paternina F.J.P., Ntumba J.K., Carevic V.V., Jakopovic M., Jankovic M., Matkovic Z., Mitrecic I., Jacobsson M.B., Christensen A.B., Bodtger U.C.H., Meyer C.N., Jensen A.V., Baunbaek-Knudsen G., Petersen P.T., Andersen S., El-Wahhab I.E.A., Morsy N.E., Shafiek H., Sobh E., Abdulsemed K.A., Bertrand F., Brun-Buisson C., de Montmollin E., Fartoukh M., Messika J., Tattevin P., Khoury A., Ebruke B., Dreher M., Kolditz M., Meisinger M., Niederlausitz K., Pletz M.W., Hagel S., Schaberg T., Spielmanns M., Creutz P., Suttorp N., Siaw-Lartey B., Dimakou K., Papapetrou D., Tsigou E., Ampazis D., Kaimakamis E., Bhatia M., Dhar R., D'Souza G., Garg R., Koul P.A., Mahesh P.A., Jayaraj B.S., Narayan K.V., Udnur H.B., Krishnamurthy S.B., Kant S., Swarnakar R., Limaye S., Salvi S., Golshani K., Keatings V.M., Martin-Loeches I., Maor Y., Strahilevitz J., Battaglia S., Carrabba M., Ceriana P., Confalonieri M., Monforte A.D., Prato B.D., Rosa M., Fantini R., Fiorentino G., Gammino M.A., Menzella F., Milani G., Nava S., Palmiero G., Petrino R., Gabrielli B., Rossi P., Sorino C., Steinhilber G., Zanforlin A., Franzetti F., Carugati M., Morosi M., Monge E., Carone M., Patella V., Scarlata S., Comel A., Kurahashi K., Bacha Z.A., Ugalde D.B., Zuniga O.C., Villegas J.F., Medenica M., van de Garde E.M.W., Mihsra D.R., Shrestha P., Ridgeon E., Awokola B.I., Nwankwo O.N.O., Olufunlola A.B., Olumide S., Ukwaja K.N., Irfan M., Minarowski L., Szymon S., Froes F., Leuschner P., Meireles M., Ferrao C., Neves J., Ravara S.B., Brocovschii V., Ion C., Rusu D., Toma C., Chirita D., Dorobat C.M., Birkun A., Kaluzhenina A., Almotairi A., Bukhary Z.A.A., Edathodu J., Fathy A., Enani A.M.A., Mohamed N.E., Memon J.U., Bella A., Bogdanovic N., Milenkovic B., Pesut D., Borderias L., Garcia N.M.B., Alarcon H.C., Cilloniz C., Torres A., Diaz-Brito V., Casas X., Gonzalez A.E., Fernandez-Almira ML., Gallego M., Gaspar-GarcIa I., Victoria P.J., Martinez E.L., de Molina R.M., Marcos P.J., Menendez R., Pando-Sandoval A., Aymerich C.P., de la Torre A.L., Garcia-Olive I., Rello J., Moyano S., Sanz F., Sibila O., Rodrigo-Troyano A., Sole-Violan J., Uranga A., van Boven J.F.M., Torra E.V., Pujol J.A., Feldman C., Yum H.K., Fiogbe A.A., Yangui F., Bilaceroglu S., Dalar L., Yilmaz U., Bogomolov A., Elahi N., Dhasmana D.J., Feneley A., Ions R., Skeemer J., Woltmann G., Hancock C., Hill A.T., Rudran B., Ruiz-Buitrago S., Campbell M., Whitaker P., Youzguin A., Singanayagam A., Allen K.S., Brito V., Dietz J., Dysart C.E., Kellie S.M., Franco-Sadud R.A., Meier G., Gaga M., Holland T.L., Bergin S.P., Kheir F., Landmeier M., Lois M., Nair G.B., Patel H., Reyes K., Rodriguez-Cintron W., Saito S., Soni N.J., Noda J., Hinojosa C.I., Levine S.M., Angel L.F., Anzueto A., Whitlow K.S., Hipskind J., Sukhija K., Totten V., Wunderink R.G., Shah R.D., Mateyo K.J., Noriega L., Alvarado E., Aman M., and Labra L.
Subjects: 0301 basic medicine, Male, Pediatrics, Etiology, Multidrug-resistant pathogen, MRSA, Pneumocystis pneumonia, Pneumònia adquirida a la comunitat, HOSPITALIZED-PATIENTS, 0302 clinical medicine, Community-acquired pneumonia, Risk Factors, Prevalence, Medicine, 030212 general & internal medicine, PNEUMOCYSTIS PNEUMONIA, Articles and Commentaries, Aged, 80 and over, Respiratory tract infections, Anemia, Aplastic, Middle Aged, 3. Good health, Community-Acquired Infections, Europe, Infectious Diseases, Immunocompromise, Microbiology, Multidrug-resistant pathogens, Pneumonia, Etiologia, Hematologic Neoplasms, Female, BLOOD-STREAM INFECTIONS, Lung Transplantation, Microbiology (medical), medicine.medical_specialty, Asia, Neutropenia, 030106 microbiology, RESPIRATORY-TRACT INFECTIONS, Settore MED/10 - Malattie Dell'Apparato Respiratorio, TRANSPLANT RECIPIENTS, DISEASES-SOCIETY, 03 medical and health sciences, Immunocompromised Host, Pneumonia, Bacterial, MANAGEMENT, Humans, pneumonia, BACTERIAL PNEUMONIA, Aged, Acquired Immunodeficiency Syndrome, business.industry, microbiology, Bacterial pneumonia, Australia, medicine.disease, multidrug-resistant pathogens, Mycoses, Bacteremia, Africa, RISK-FACTORS, immunocompromise, Americas, business
Abstract: Background The correct management of immunocompromised patients with pneumonia is debated. We evaluated the prevalence, risk factors, and characteristics of immunocompromised patients coming from the community with pneumonia. Methods We conducted a secondary analysis of an international, multicenter study enrolling adult patients coming from the community with pneumonia and hospitalized in 222 hospitals in 54 countries worldwide. Risk factors for immunocompromise included AIDS, aplastic anemia, asplenia, hematological cancer, chemotherapy, neutropenia, biological drug use, lung transplantation, chronic steroid use, and solid tumor. Results At least 1 risk factor for immunocompromise was recorded in 18% of the 3702 patients enrolled. The prevalences of risk factors significantly differed across continents and countries, with chronic steroid use (45%), hematological cancer (25%), and chemotherapy (22%) the most common. Among immunocompromised patients, community-acquired pneumonia (CAP) pathogens were the most frequently identified, and prevalences did not differ from those in immunocompetent patients. Risk factors for immunocompromise were independently associated with neither Pseudomonas aeruginosa nor non–community-acquired bacteria. Specific risk factors were independently associated with fungal infections (odds ratio for AIDS and hematological cancer, 15.10 and 4.65, respectively; both P = .001), mycobacterial infections (AIDS; P = .006), and viral infections other than influenza (hematological cancer, 5.49; P < .001). Conclusions Our findings could be considered by clinicians in prescribing empiric antibiotic therapy for CAP in immunocompromised patients. Patients with AIDS and hematological cancer admitted with CAP may have higher prevalences of fungi, mycobacteria, and noninfluenza viruses.
Published: 2019
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10. Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment

Author: European Commission, Instituto de Salud Carlos III, Fundación Científica Asociación Española Contra el Cáncer, Ministerio de Economía y Competitividad (España), Fundación Ramón Areces, Principado de Asturias, German Research Foundation, European Research Council, Asociación Española Contra el Cáncer, Fundación Fero, Fundación la Caixa, Josep Carreras Leukemia Foundation, Generalitat de Catalunya, Obra Social Cajastur, Urdinguio, Rocío G., López, Virginia, Bayón, Gustavo F., Díaz de la Guardia, Rafael, Sierra, Marta I., García-Toraño, Estela, Pérez, Raúl F., García, María G., Carella, Antonella, Pruneda, Patricia C., Prieto López, Cristina, Dmitrijeva, Marija, Santamarina-Ojeda, Pablo, Belmonte, Thalia, Mangas, Cristina, Diaconu, Elena, Ferrero, Cecilia, Tejedor, Juan Ramón, Fernández-Morera, Juan L., Bravo, Cristina, Bueno, Clara, Sanjuan-Pla, Alejandra, Rodríguez López, Ramón María, Suárez-Álvarez, Beatriz, López-Larrea, Carlos, Bernal, Teresa, Colado, Enrique, Balbín, Milagros, García-Suarez, Olivia, Chiara, María-Dolores, Sáenz-de-Santa-María, Inés, Rodríguez Hernández, Francisco José, Pando-Sandoval, Ana, Rodrigo, Luis, Santos, Laura, Salas, Ana, Vallejo-Díaz, Jesús, Carrera, Ana C., Rico, Daniel, Hernández-López, Inmaculada, Vayá, Amparo, Ricart, José M., Seto, Edward, Sima-Teruel, Núria, Vaquero, Alejandro, Valledor, Luis, Cañal, María Jesús, Pisano, David, Graña-Castro, Osvaldo, Thomas, Tim, Voss, Anne K., Menéndez, Pablo, Villar-Garea, Ana, Deutzmann, Rainer, Fernández, Agustín F., Fraga, Mario F., European Commission, Instituto de Salud Carlos III, Fundación Científica Asociación Española Contra el Cáncer, Ministerio de Economía y Competitividad (España), Fundación Ramón Areces, Principado de Asturias, German Research Foundation, European Research Council, Asociación Española Contra el Cáncer, Fundación Fero, Fundación la Caixa, Josep Carreras Leukemia Foundation, Generalitat de Catalunya, Obra Social Cajastur, Urdinguio, Rocío G., López, Virginia, Bayón, Gustavo F., Díaz de la Guardia, Rafael, Sierra, Marta I., García-Toraño, Estela, Pérez, Raúl F., García, María G., Carella, Antonella, Pruneda, Patricia C., Prieto López, Cristina, Dmitrijeva, Marija, Santamarina-Ojeda, Pablo, Belmonte, Thalia, Mangas, Cristina, Diaconu, Elena, Ferrero, Cecilia, Tejedor, Juan Ramón, Fernández-Morera, Juan L., Bravo, Cristina, Bueno, Clara, Sanjuan-Pla, Alejandra, Rodríguez López, Ramón María, Suárez-Álvarez, Beatriz, López-Larrea, Carlos, Bernal, Teresa, Colado, Enrique, Balbín, Milagros, García-Suarez, Olivia, Chiara, María-Dolores, Sáenz-de-Santa-María, Inés, Rodríguez Hernández, Francisco José, Pando-Sandoval, Ana, Rodrigo, Luis, Santos, Laura, Salas, Ana, Vallejo-Díaz, Jesús, Carrera, Ana C., Rico, Daniel, Hernández-López, Inmaculada, Vayá, Amparo, Ricart, José M., Seto, Edward, Sima-Teruel, Núria, Vaquero, Alejandro, Valledor, Luis, Cañal, María Jesús, Pisano, David, Graña-Castro, Osvaldo, Thomas, Tim, Voss, Anne K., Menéndez, Pablo, Villar-Garea, Ana, Deutzmann, Rainer, Fernández, Agustín F., and Fraga, Mario F.
Abstract: Histone H4 acetylation at Lysine 16 (H4K16ac) is a key epigenetic mark involved in gene regulation, DNA repair and chromatin remodeling, and though it is known to be essential for embryonic development, its role during adult life is still poorly understood. Here we show that this lysine is massively hyperacetylated in peripheral neutrophils. Genome-wide mapping of H4K16ac in terminally differentiated blood cells, along with functional experiments, supported a role for this histone post-translational modification in the regulation of cell differentiation and apoptosis in the hematopoietic system. Furthermore, in neutrophils, H4K16ac was enriched at specific DNA repeats. These DNA regions presented an accessible chromatin conformation and were associated with the cleavage sites that generate the 50 kb DNA fragments during the first stages of programmed cell death. Our results thus suggest that H4K16ac plays a dual role in myeloid cells as it not only regulates differentiation and apoptosis, but it also exhibits a non-canonical structural role in poising chromatin for cleavage at an early stage of neutrophil cell death.
Published: 2019

11. Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment

Author: Urdinguio, Rocio G, primary, Lopez, Virginia, additional, Bayón, Gustavo F, additional, Diaz de la Guardia, Rafael, additional, Sierra, Marta I, additional, García-Toraño, Estela, additional, Perez, Raúl F, additional, García, María G, additional, Carella, Antonella, additional, Pruneda, Patricia C, additional, Prieto, Cristina, additional, Dmitrijeva, Marija, additional, Santamarina, Pablo, additional, Belmonte, Thalía, additional, Mangas, Cristina, additional, Diaconu, Elena, additional, Ferrero, Cecilia, additional, Tejedor, Juan Ramón, additional, Fernandez-Morera, Juan Luis, additional, Bravo, Cristina, additional, Bueno, Clara, additional, Sanjuan-Pla, Alejandra, additional, Rodriguez, Ramon M, additional, Suarez-Alvarez, Beatriz, additional, López-Larrea, Carlos, additional, Bernal, Teresa, additional, Colado, Enrique, additional, Balbín, Milagros, additional, García-Suarez, Olivia, additional, Chiara, María Dolores, additional, Sáenz-de-Santa-María, Inés, additional, Rodríguez, Francisco, additional, Pando-Sandoval, Ana, additional, Rodrigo, Luis, additional, Santos, Laura, additional, Salas, Ana, additional, Vallejo-Díaz, Jesús, additional, C. Carrera, Ana, additional, Rico, Daniel, additional, Hernández-López, Inmaculada, additional, Vayá, Amparo, additional, Ricart, José M, additional, Seto, Edward, additional, Sima-Teruel, Núria, additional, Vaquero, Alejandro, additional, Valledor, Luis, additional, Cañal, Maria Jesus, additional, Pisano, David, additional, Graña-Castro, Osvaldo, additional, Thomas, Tim, additional, Voss, Anne K, additional, Menéndez, Pablo, additional, Villar-Garea, Ana, additional, Deutzmann, Rainer, additional, Fernandez, Agustín F, additional, and Fraga, Mario F, additional
Published: 2019
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12. An international perspective on hospitalized patients with viral community-acquired pneumonia

Author: Radovanovic, Dejan, primary, Sotgiu, Giovanni, additional, Jankovic, Mateja, additional, Mahesh, Padukudru Anand, additional, Marcos, Pedro Jorge, additional, Abdalla, Mohamed I., additional, Di Pasquale, Marta Francesca, additional, Gramegna, Andrea, additional, Terraneo, Silvia, additional, Blasi, Francesco, additional, Santus, Pierachille, additional, Aliberti, Stefano, additional, Reyes, Luis F., additional, Restrepo, Marcos I., additional, Aruj, Patricia Karina, additional, Attorri, Silvia, additional, Barimboim, Enrique, additional, Caeiro, Juan Pablo, additional, Garzón, María I., additional, Cambursano, Victor Hugo, additional, Ceccato, Adrian, additional, Chertcoff, Julio, additional, Cordon Díaz, Ariel, additional, de Vedia, Lautaro, additional, Ganaha, Maria Cristina, additional, Lambert, Sandra, additional, Lopardo, Gustavo, additional, Luna, Carlos M., additional, Malberti, Alessio Gerardo, additional, Morcillo, Nora, additional, Tartara, Silvina, additional, Pensotti, Claudia, additional, Pereyra, Betiana, additional, Scapellato, Pablo Gustavo, additional, Stagnaro, Juan Pablo, additional, Shah, Sonali, additional, Lötsch, Felix, additional, Thalhammer, Florian, additional, Anseeuw, Kurt, additional, Francois, Camille A., additional, Van Braeckel, Eva, additional, Vincent, Jean Louis, additional, Djimon, Marcel Zannou, additional, Aranha Nouér, Simone, additional, Chipev, Peter, additional, Encheva, Milena, additional, Miteva, Darina, additional, Petkova, Diana, additional, Balkissou, Adamou Dodo, additional, Pefura Yone, Eric Walter, additional, Mbatchou Ngahane, Bertrand Hugo, additional, Shen, Ning, additional, Xu, Jin-fu, additional, Bustamante Rico, Carlos Andres, additional, Buitrago, Ricardo, additional, Pereira Paternina, Fernando Jose, additional, Kayembe Ntumba, Jean-Marie, additional, Vladic-Carevic, Vesna, additional, Jakopovic, Marko, additional, Matkovic, Zinka, additional, Mitrecic, Ivan, additional, Bouchy Jacobsson, Marie-Laure, additional, Bro Christensen, Anette, additional, Bødtger, Uffe, additional, Meyer, Christian Niels, additional, Vestergaard Jensen, Andreas, additional, El-Said Abd El-Wahhab, Ibrahim, additional, Elsayed Morsy, Nesreen, additional, Shafiek, Hanaa, additional, Sobh, Eman, additional, Abdulsemed, Kedir Abdella, additional, Bertrand, Fabrice, additional, Brun-Buisson, Christian, additional, de Montmollin, Etienne, additional, Fartoukh, Muriel, additional, Messika, Jonathan, additional, Tattevin, Pierre, additional, Khoury, Abdo, additional, Ebruke, Bernard, additional, Dreher, Michael, additional, Kolditz, Martin, additional, Meisinger, Matthias, additional, Pletz, Mathias W., additional, Hagel, Stefan, additional, Rupp, Jan, additional, Schaberg, Tom, additional, Spielmanns, Marc, additional, Creutz, Petra, additional, Suttorp, Norton, additional, Siaw-Lartey, Beatrice, additional, Dimakou, Katerina, additional, Papapetrou, Dimosthenis, additional, Tsigou, Evdoxia, additional, Ampazis, Dimitrios, additional, Kaimakamis, Evangelos, additional, Bhatia, Mohit, additional, Dhar, Raja, additional, D’Souza, George, additional, Garg, Rajiv, additional, Koul, Parvaiz A., additional, Jayaraj, B.S., additional, Narayan, Kiran Vishnu, additional, Udnur, Hirennappa B., additional, Krishnamurthy, Shashi Bhaskara, additional, Kant, Surya, additional, Swarnakar, Rajesh, additional, Salvi, Sundeep, additional, Limaye, Sneha, additional, Golshani, Keihan, additional, Keatings, Vera M., additional, Martin-Loeches, Ignacio, additional, Maor, Yasmin, additional, Strahilevitz, Jacob, additional, Battaglia, Salvatore, additional, Carrabba, Maria, additional, Ceriana, Piero, additional, Confalonieri, Marco, additional, d’Arminio Monforte, Antonella, additional, Del Prato, Bruno, additional, De Rosa, Marino, additional, Fantini, Riccardo, additional, Fiorentino, Giuseppe, additional, Gammino, Maria Antonia, additional, Menzella, Francesco, additional, Milani, Giuseppe, additional, Nava, Stefano, additional, Palmiero, Gerardo, additional, Petrino, Roberta, additional, Gabrielli, Barbra, additional, Rossi, Paolo, additional, Sorino, Claudio, additional, Steinhilber, Gundi, additional, Zanforlin, Alessandro, additional, Franzetti, Fabio, additional, Carone, Mauro, additional, Patella, Vincenzo, additional, Scarlata, Simone, additional, Comel, Andrea, additional, Kurahashi, Kiyoyasu, additional, Aoun Bacha, Zeina, additional, Barajas Ugalde, Daniel, additional, Ceballos Zuñiga, Omar, additional, Villegas, José F., additional, Medenica, Milic, additional, van de Garde, E.M.W., additional, Raj Mihsra, Deebya, additional, Shrestha, Poojan, additional, Ridgeon, Elliott, additional, Ishola Awokola, Babatunde, additional, Nwankwo, Ogonna N.O., additional, Olufunlola, Adefuye Bolanle, additional, Olumide, Segaolu, additional, Ukwaja, Kingsley N., additional, Irfan, Muhammad, additional, Minarowski, Lukasz, additional, Szymon, Skoczyński, additional, Froes, Felipe, additional, Leuschner, Pedro, additional, Meireles, Mariana, additional, Ferrão, Cláudia, additional, Neves, João, additional, Ravara, Sofia B., additional, Brocovschii, Victoria, additional, Ion, Chesov, additional, Rusu, Doina, additional, Toma, Cristina, additional, Chirita, Daniela, additional, Dorobat, Carmen Mihaela, additional, Birkun, Alexei, additional, Kaluzhenina, Anna, additional, Almotairi, Abdullah, additional, Bukhary, Zakeya Abdulbaqi Ali, additional, Edathodu, Jameela, additional, Fathy, Amal, additional, Mushira Abdulaziz Enani, Abdullah, additional, Eltayeb Mohamed, Nazik, additional, Ulhadi Memon, Jawed, additional, Bella, Abdelhaleem, additional, Bogdanović, Nada, additional, Milenkovic, Branislava, additional, Pesut, Dragica, additional, Borderìas, Luis, additional, Bordon Garcia, Noel Manuel, additional, Cabello Alarcón, Hugo, additional, Cilloniz, Catia, additional, Torres, Antoni, additional, Diaz-Brito, Vicens, additional, Casas, Xavier, additional, Encabo González, Alicia, additional, Fernández-Almira, Maria Luisa, additional, Gallego, Miguel, additional, Gaspar-GarcÍa, Inmaculada, additional, González Del Castillo, Juan, additional, Javaloyes Victoria, Patricia, additional, Laserna Martínez, Elena, additional, Malo de Molina, Rosa, additional, Menéndez, Rosario, additional, Pando-Sandoval, Ana, additional, Prat Aymerich, Cristina, additional, Lacoma de la Torre, Alicia, additional, García-Olivé, Ignasi, additional, Rello, Jordi, additional, Moyano, Silvia, additional, Sanz, Francisco, additional, Sibila, Oriol, additional, Rodrigo-Troyano, Ana, additional, Solé-Violán, Jordi, additional, Uranga, Ane, additional, van Boven, Job F.M., additional, Vendrell Torra, Ester, additional, Pujol, Jordi Almirall, additional, Feldman, Charles, additional, Kee Yum, Ho, additional, Fiogbe, Arnauld Attannon, additional, Yangui, Ferdaous, additional, Bilaceroglu, Semra, additional, Dalar, Levent, additional, Yilmaz, Ufuk, additional, Bogomolov, Artemii, additional, Elahi, Naheed, additional, Dhasmana, Devesh J., additional, Feneley, Andrew, additional, Hancock, Carole, additional, Hill, Adam T., additional, Rudran, Banu, additional, Ruiz-Buitrago, Silvia, additional, Campbell, Marion, additional, Whitaker, Paul, additional, Youzguin, Alexander, additional, Singanayagam, Anika, additional, Allen, Karen S., additional, Brito, Veronica, additional, Dietz, Jessica, additional, Dysart, Claire E., additional, Kellie, Susan M., additional, Franco-Sadud, Ricardo A., additional, Meier, Garnet, additional, Gaga, Mina, additional, Holland, Thomas L., additional, Bergin, Stephen P., additional, Kheir, Fayez, additional, Landmeier, Mark, additional, Lois, Manuel, additional, Nair, Girish B., additional, Patel, Hemali, additional, Reyes, Katherine, additional, Rodriguez-Cintron, William, additional, Saito, Shigeki, additional, Soni, Nilam J., additional, Noda, Julio, additional, Hinojosa, Cecilia I., additional, Levine, Stephanie M., additional, Angel, Luis F., additional, Anzueto, Antonio, additional, Scott Whitlow, K., additional, Hipskind, John, additional, Sukhija, Kunal, additional, Totten, Vicken, additional, Wunderink, Richard G., additional, Shah, Ray D., additional, Mateyo, Kondwelani John, additional, Carugati, Manuela, additional, Morosi, Manuela, additional, and Monge, Elisa, additional
Published: 2019
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13. From cytology to histology: diagnosis of a relapsed mediastinal lymphoma by endobronchial ultrasound transbronchial histological needle

Author: Ariza-Prota, Miguel Angel, Bango Álvarez, Antonio, Pérez, Liliana, Pando-Sandoval, Ana, Fuentes, Nelson, and Casan, Pere
Subjects: histological, needle, lymphoma, Case Reports, Endobronchial ultrasound
Abstract: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is highly accurate in diagnosing mediastinal lymphadenopathies of lung cancer and benign disorders, with the advantage that it is a minimally invasive technique, unlike open surgery and mediastinoscopy. However, the diagnostic accuracy of EBUS-TBNA for the diagnosis of lymphoma in patients with mediastinal lymphadenopathy is not well defined. The lack of tissue architecture obtained by cytological needles decreases the diagnostic accuracy for diagnosis and subtyping of de novo and relapsed mediastinal lymphomas. We present the first described case in the literature of an anaplastic large cell lymphoma relapsed, diagnosed on tissue fragments obtained by EBUS-TBNA with the particularity of using a histological needle.
Published: 2015

14. Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment

Author: European Commission, Urdinguio, Rocío G., López, Virginia, Bayón, Gustavo F., Díaz de la Guardia, Rafael, Sierra, Marta I., García-Toraño, Estela, Pérez, Raúl F., García, María G., Carella, Antonella, Pruneda, Patricia C., Prieto López, Cristina, Dmitrijeva, Marija, Santamarina-Ojeda, Pablo, Belmonte, Thalia, Mangas, Cristina, Diaconu, Elena, Ferrero, Cecilia, Tejedor, Juan Ramón, Fernández-Morera, Juan L., Bravo, Cristina, Bueno, Clara, Sanjuan-Pla, Alejandra, Rodríguez López, Ramón María, Suárez-Álvarez, Beatriz, López-Larrea, Carlos, Bernal, Teresa, Colado, Enrique, Balbín, Milagros, García-Suarez, Olivia, Chiara, María-Dolores, Sáenz-de-Santa-María, Inés, Rodríguez Hernández, Francisco José, Pando-Sandoval, Ana, Rodrigo, Luis, Santos, Laura, Salas, Ana, Vallejo-Díaz, Jesús, Carrera, Ana C., Rico, Daniel, Hernández-López, Inmaculada, Vayá, Amparo, Ricart, José M., Seto, Edward, Sima-Teruel, Núria, Vaquero, Alejandro, Valledor, Luis, Cañal, María Jesús, Pisano, David, Graña-Castro, Osvaldo, Thomas, Tim, Voss, Anne K., Menéndez, Pablo, Villar-Garea, Ana, Deutzmann, Rainer, Fernández, Agustín F., Fraga, Mario F., European Commission, Urdinguio, Rocío G., López, Virginia, Bayón, Gustavo F., Díaz de la Guardia, Rafael, Sierra, Marta I., García-Toraño, Estela, Pérez, Raúl F., García, María G., Carella, Antonella, Pruneda, Patricia C., Prieto López, Cristina, Dmitrijeva, Marija, Santamarina-Ojeda, Pablo, Belmonte, Thalia, Mangas, Cristina, Diaconu, Elena, Ferrero, Cecilia, Tejedor, Juan Ramón, Fernández-Morera, Juan L., Bravo, Cristina, Bueno, Clara, Sanjuan-Pla, Alejandra, Rodríguez López, Ramón María, Suárez-Álvarez, Beatriz, López-Larrea, Carlos, Bernal, Teresa, Colado, Enrique, Balbín, Milagros, García-Suarez, Olivia, Chiara, María-Dolores, Sáenz-de-Santa-María, Inés, Rodríguez Hernández, Francisco José, Pando-Sandoval, Ana, Rodrigo, Luis, Santos, Laura, Salas, Ana, Vallejo-Díaz, Jesús, Carrera, Ana C., Rico, Daniel, Hernández-López, Inmaculada, Vayá, Amparo, Ricart, José M., Seto, Edward, Sima-Teruel, Núria, Vaquero, Alejandro, Valledor, Luis, Cañal, María Jesús, Pisano, David, Graña-Castro, Osvaldo, Thomas, Tim, Voss, Anne K., Menéndez, Pablo, Villar-Garea, Ana, Deutzmann, Rainer, Fernández, Agustín F., and Fraga, Mario F.
Abstract: Histone H4 acetylation at Lysine 16 (H4K16ac) is a key epigenetic mark involved in gene regulation, DNA repair and chromatin remodeling, and though it is known to be essential for embryonic development, its role during adult life is still poorly understood. Here we show that this lysine is massively hyperacetylated in peripheral neutrophils. Genome-wide mapping of H4K16ac in terminally differentiated blood cells, along with functional experiments, supported a role for this histone post-translational modification in the regulation of cell differentiation and apoptosis in the hematopoietic system. Furthermore, in neutrophils, H4K16ac was enriched at specific DNA repeats. These DNA regions presented an accessible chromatin conformation and were associated with the cleavage sites that generate the 50 kb DNA fragments during the first stages of programmed cell death. Our results thus suggest that H4K16ac plays a dual role in myeloid cells as it not only regulates differentiation and apoptosis, but it also exhibits a non-canonical structural role in poising chromatin for cleavage at an early stage of neutrophil cell death.
Published: 2018

15. Cost of Hospitalizations due to Exacerbation in Patients with Non-Cystic Fibrosis Bronchiectasis

Author: de la Rosa Carrillo, David, primary, Navarro Rolon, Annie, additional, Girón Moreno, Rosa Maria, additional, Montull Veiga, Beatriz, additional, Olveira Fuster, Casilda, additional, Padilla Galo, Alicia, additional, Prados Sánchez, Concepción, additional, Quintana Gallego, Esther, additional, Sibila Vidal, Oriol , additional, Celorrio Jiménez, Nuria, additional, Ruiz Peña, Antonio, additional, Torres Martí, Antoni, additional, Avilés Inglés, Maria Jesús, additional, Blanco Aparicio, Marina, additional, García-Clemente, Marta, additional, Golpe Gómez, Rafael, additional, Gómez Bonilla, Ainhoa, additional, Gómez González, Cristina, additional, Leal Arranz, Maria Victoria, additional, Mínguez Clemente, Patricia, additional, López Muñiz, Belén, additional, Máiz Carro, Luis, additional, Pando Sandoval, Ana, additional, Rodríguez Hermosa, Juan Luis, additional, Uranga Echeverria, Ane, additional, Núñez Ares, Ana, additional, López Roldán, Lorena, additional, Abellán Martínez, Carmen, additional, Martínez García, Abel Jesús, additional, Michel de la Rosa, Francisco Javier, additional, Godoy Mayoral, Raúl, additional, and Martínez-García, Miguel Ángel, additional
Published: 2018
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16. Community-Acquired Moraxella catarrhalis Bacteremic Pneumonia: Two Case Reports and Review of the Literature

Author: Ariza-Prota, Miguel Angel, Pando-Sandoval, Ana, García-Clemente, Marta, Fole-Vázquez, David, and Casan, Pere
Subjects: Article Subject, bacteria, respiratory tract diseases
Abstract: Moraxella (formerly Branhamella) catarrhalis was discovered at the end of the nineteenth century, and for many decades it was considered to be a harmless commensal of the upper respiratory tract. It is a Gram-negative, aerobic diplococcus considered to be the third most common pathogen isolated in childhood sinusitis and otitis media and in adult chronic lower respiratory disease, as well as an etiological agent of pneumonia in immunosuppressed patients or those with chronic obstructive pulmonary disease. Moraxella catarrhalis pneumonia is rarely associated with bacteremia. Here, we present two cases of community-acquired Moraxella catarrhalis bacteremic pneumonia.
Published: 2016
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17. Tracheobronchial amyloidosis: Diagnosis, treatment and evolution in 5 patients

Author: Pando Sandoval, Ana, Ariza Prota, Miguel Angel, García Clemente, Marta, and Casan, Pere
Published: 2015
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18. Aspiration Risk Factors, Microbiology, and Empiric Antibiotics for Patients Hospitalized With Community-Acquired Pneumonia

Author: Marin-Corral, Judith, Pascual-Guardia, Sergi, Amati, Francesco, Aliberti, Stefano, Masclans, Joan R., Soni, Nilam, Rodriguez, Alejandro, Sibila, Oriol, Sanz, Francisco, Sotgiu, Giovanni, Anzueto, Antonio, Dimakou, Katerina, Petrino, Roberta, van de Garde, Ewoudt, Restrepo, Marcos I., Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I., Cambursano, Victor Hugo, Adrian Ceccato, V. H. Dr Cazaux A., Chertcoff, Julio, Lascar, Florencia, Di Tulio, Fernando, Díaz, Ariel Cordon, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M., Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Anseeuw, Kurt, Francois, Camille A., Van Braeckel, Eva, Vincent, Jean Louis, Djimon, Marcel Zannou, Bashi, Jules, Dodo, Roger, Nouér, Simone Aranha, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Balkissou, Adamou Dodo, Pefura Yone, Eric Walter, Mbatchou Ngahane, Bertrand Hugo, Shen, Ning, Xu, Jin-fu, Bustamante Rico, Carlos Andres, Buitrago, Ricardo, Pereira Paternina, Fernando Jose, Kayembe Ntumba, Jean-Marie, Carevic, Vesna Vladic, Jakopovic, Marko, Jankovic, Mateja, Matkovic, Zinka, Mitrecic, Ivan, Bouchy Jacobsson, Marie-Laure, Christensen, Anette Bro, Heitmann Bødtger, Uffe Christian, Meyer, Christian Niels, Jensen, Andreas Vestergaard, Baunbæk-knudsen, Gertrud, Petersen, Pelle Trier, Andersen, Stine, El-Said Abd El-Wahhab, Ibrahim, Morsy, Nesreen Elsayed, Shafiek, Hanaa, Sobh, Eman, Abdulsemed, Kedir Abdella, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Pletz, Mathias W., Hagel, Stefan, Rupp, Jan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Kaimakamis, Evangelos, Bhatia, Mohit, Dhar, Raja, D’Souza, George, Garg, Rajiv, Koul, Parvaiz A., Mahesh, P.A., Jayaraj, B.S., Narayan, Kiran Vishnu, Udnur, Hirennappa B., Krishnamurthy, Shashi Bhaskara, Kant, Surya, Swarnakar, Rajesh, Limaye, Sneha, Salvi, Sundeep, Golshani, Keihan, Keatings, Vera M., Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Faverio, Paola, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, Monforte, Antonella d’Arminio, Del Prato, Bruno, De Rosa, Marino, Fantini, Riccardo, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, San Luca, Ospedale, Franzetti, Fabio, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Bacha, Zeina Aoun, Ugalde, Daniel Barajas, Zuñiga, Omar Ceballos, Villegas, José F., Medenica, Milic, Mihsra, Deebya Raj, Shrestha, Poojan, Ridgeon, Elliott, Awokola, Babatunde Ishola, Adefuye Bolanle Olufunlola, Ogonna N.O., Olumide, Segaolu, Ukwaja, Kingsley N., Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczyński, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Leuschner, Pedro, Neves, João, Salazar, Abel, Ravara, Sofia B., Brocovschii, Victoria, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Dorobat, Carmen Mihaela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Ali Bukhary, Zakeya Abdulbaqi, Edathodu, Jameela, Fathy, Amal, Abdulaziz Enani, Abdullah Mushira, Mohamed, Nazik Eltayeb, Memon, Jawed Ulhadi, Bella, Abdelhaleem, Bogdanović, Serbia: Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Bordon Garcia, Noel Manuel, Alarcón, Hugo Cabello, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, González, Alicia Encabo, Fernández-Almira, Maria Luisa, Interna, Medicina, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, González del Castillo, Juan, Victoria, Patricia Javaloyes, Martínez, Elena Laserna, Malo de Molina, Rosa, Marcos, Pedro J., Menéndez, Rosario, Pando-Sandoval, Ana, Aymerich, Cristina Prat, Lacoma de la Torre, Alicia, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, van Boven, Job FM., Torra, Ester Vendrell, Pujol, Jordi Almirall, Feldman, Charles, Yum, Ho Kee, Arnauld Attannon Fiogbe, Inje Univ., Yangui, Ferdaous, Bilaceroglu, Semra, Levent Dalar, Izmir Dr., Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J., Feneley, Andrew, Hill, Adam T., Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Hancock, C., Villafuerte, David, Allen, Karen S., Brito, Veronica, Dietz, Jessica, Dysart, Claire E., Kellie, Susan M., Ricardo A. Franco-Sadud, Clement J., Meier, Garnet, Gaga, Mina, Holland, Thomas L., Bergin, Stephen P., Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B., Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Noda, Julio, Hinojosa, Cecilia I., Levine, Stephanie M., Reyes, Luis F., Angel, Luis F., Anzueto, Antonio, Whitlow, K. Scott, Hipskind, John, Sukhija, Kunal, Totten, Vicken, Wunderink, Richard G., Shah, Ray D., Mateyo, Kondwelani John, Noriega, Lorena, Alvarado, Ezequiel, Aman, Mohamed, and Labra, Lucía
Abstract: Aspiration community-acquired pneumonia (ACAP) and community-acquired pneumonia (CAP) in patients with aspiration risk factors (AspRFs) are infections associated with anaerobes, but limited evidence suggests their pathogenic role.
Published: 2021
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19. Transbronchial cryobiopsy in interstitial lung disease: experience in 106 cases – how to do it

Author: Bango-Álvarez, Antonio, primary, Ariza-Prota, Miguel, additional, Torres-Rivas, Hector, additional, Fernández-Fernández, Luis, additional, Prieto, Amador, additional, Sánchez, Inmaculada, additional, Gil, Maria, additional, and Pando-Sandoval, Ana, additional
Published: 2017
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20. Community-Acquired Pneumonia and Empyema Caused by Citrobacter koseri in an Immunocompetent Patient

Author: Ariza-Prota, Miguel Angel, Pando-Sandoval, Ana, García-Clemente, Marta, Fernández, Ramón, and Casan, Pere
Subjects: Article Subject
Abstract: Citrobacter species, belonging to the family Enterobacteriaceae, are environmental organisms commonly found in soil, water, and the intestinal tracts of animals and humans. Citrobacter koseri is known to be an uncommon but serious cause of both sporadic and epidemic septicemia and meningitis in neonates and young infants. Most cases reported have occurred in immunocompromised hosts. The infections caused by Citrobacter are difficult to treat with usual broad spectrum antibiotics owing to rapid generation of mutants and have been associated with high death rates in the past. We believe this is the first case described in the literature of a community-acquired pneumonia and empyema caused by Citrobacter koseri in an immunocompetent adult patient.
Published: 2015
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21. Global initiative for meticillin-resistant Staphylococcus aureus pneumonia (GLIMP): an international, observational cohort study

Author: Aliberti, Stefano, primary, Reyes, Luis F, additional, Faverio, Paola, additional, Sotgiu, Giovanni, additional, Dore, Simone, additional, Rodriguez, Alejandro H, additional, Soni, Nilam J, additional, Restrepo, Marcos I, additional, Aruj, Patricia Karina, additional, Attorri, Silvia, additional, Barimboim, Enrique, additional, Caeiro, Juan Pablo, additional, Garzón, María I, additional, Cambursano, Victor Hugo, additional, Ceccato, Adrian, additional, Chertcoff, Julio, additional, Lascar, Florencia, additional, Di Tulio, Fernando, additional, Cordon Díaz, Ariel, additional, de Vedia, Lautaro, additional, Ganaha, Maria Cristina, additional, Lambert, Sandra, additional, Lopardo, Gustavo, additional, Luna, Carlos M, additional, Malberti, Alessio Gerardo, additional, Morcillo, Nora, additional, Tartara, Silvina, additional, Pensotti, Claudia, additional, Pereyra, Betiana, additional, Scapellato, Pablo Gustavo, additional, Stagnaro, Juan Pablo, additional, Shah, Sonali, additional, Lötsch, Felix, additional, Thalhammer, Florian, additional, Vincent, Jean Louis, additional, Anseeuw, Kurt, additional, Francois, Camille A, additional, Van Braeckel, Eva, additional, Djimon, Marcel Zannou, additional, Bashi, Jules, additional, Dodo, Roger, additional, Aranha Nouér, Simone, additional, Chipev, Peter, additional, Encheva, Milena, additional, Miteva, Darina, additional, Petkova, Diana, additional, Balkissou, Adamou Dodo, additional, Pefura Yone, Eric Walter, additional, Mbatchou Ngahane, Bertrand Hugo, additional, Shen, Ning, additional, Xu, Jin-fu, additional, Bustamante Rico, Carlos Andres, additional, Buitrago, Ricardo, additional, Pereira Paternina, Fernando Jose, additional, Kayembe Ntumba, Jean-Marie, additional, Vladic Carevic, Vesna, additional, Jakopovic, Marko, additional, Jankovic, Mateja, additional, Matkovic, Zinka, additional, Mitrecic, Ivan, additional, Bouchy Jacobsson, Marie-Laure, additional, Bro Christensen, Anette, additional, Heitmann Bødtger, Uffe Christian, additional, Meyer, Christian Niels, additional, Vestergaard Jensen, Andreas, additional, Baunbæk-knudsen, Gertrud, additional, Trier Petersen, Pelle, additional, Andersen, Stine, additional, El-Said Abd El-Wahhab, Ibrahim, additional, Elsayed Morsy, Nesreen, additional, Shafiek, Hanaa, additional, Sobh, Eman, additional, Abdulsemed, Kedir Abdella, additional, Bertrand, Fabrice, additional, Brun-Buisson, Christian, additional, de Montmollin, Etienne, additional, Fartoukh, Muriel, additional, Messika, Jonathan, additional, Tattevin, Pierre, additional, Khoury, Abdo, additional, Ebruke, Bernard, additional, Dreher, Michael, additional, Kolditz, Martin, additional, Meisinger, Matthias, additional, Pletz, Mathias W, additional, Hagel, Stefan, additional, Rupp, Jan, additional, Schaberg, Tom, additional, Spielmanns, Marc, additional, Creutz, Petra, additional, Suttorp, Norton, additional, Siaw-Lartey, Beatrice, additional, Dimakou, Katerina, additional, Papapetrou, Dimosthenis, additional, Tsigou, Evdoxia, additional, Ampazis, Dimitrios, additional, Kaimakamis, Evangelos, additional, Bhatia, Mohit, additional, Dhar, Raja, additional, D'Souza, George, additional, Garg, Rajiv, additional, Koul, Parvaiz A, additional, Mahesh, P A, additional, Jayaraj, B S, additional, Narayan, Kiran Vishnu, additional, Udnur, Hirennappa B, additional, Krishnamurthy, Shashi Bhaskara, additional, Kant, Surya, additional, Swarnakar, Rajesh, additional, Limaye, Sneha, additional, Salvi, Sundeep, additional, Golshani, Keihan, additional, Keatings, Vera M, additional, Martin-Loeches, Ignacio, additional, Maor, Yasmin, additional, Strahilevitz, Jacob, additional, Battaglia, Salvatore, additional, Carrabba, Maria, additional, Ceriana, Piero, additional, Confalonieri, Marco, additional, d'Arminio Monforte, Antonella, additional, Del Prato, Bruno, additional, De Rosa, Marino, additional, Fantini, Riccardo, additional, Fiorentino, Giuseppe, additional, Gammino, Maria Antonia, additional, Menzella, Francesco, additional, Milani, Giuseppe, additional, Nava, Stefano, additional, Palmiero, Gerardo, additional, Petrino, Roberta, additional, Gabrielli, Barbra, additional, Rossi, Paolo, additional, Sorino, Claudio, additional, Steinhilber, Gundi, additional, Zanforlin, Alessandro, additional, Franzetti, Fabio, additional, Carugati, Manuela, additional, Morosi, Manuela, additional, Monge, Elisa, additional, Carone, Mauro, additional, Patella, Vincenzo, additional, Scarlata, Simone, additional, Comel, Andrea, additional, Kurahashi, Kiyoyasu, additional, Aoun Bacha, Zeina, additional, Barajas Ugalde, Daniel, additional, Ceballos Zuñiga, Omar, additional, Villegas, José F, additional, Medenica, Milic, additional, van de Garde, E M W, additional, Raj Mihsra, Deebya, additional, Shrestha, Poojan, additional, Ridgeon, Elliott, additional, Ishola Awokola, Babatunde, additional, Nwankwo, Ogonna N O, additional, Olufunlola, Adefuye Bolanle, additional, Olumide, Segaolu, additional, Ukwaja, Kingsley N, additional, Irfan, Muhammad, additional, Minarowski, Lukasz, additional, Szymon, Skoczynski, additional, Froes, Felipe, additional, Leuschner, Pedro, additional, Meireles, Mariana, additional, Ferrão, Cláudia, additional, Neves, João, additional, Ravara, Sofia B, additional, Brocovschii, Victoria, additional, Ion, Chesov, additional, Rusu, Doina, additional, Toma, Cristina, additional, Chirita, Daniela, additional, Dorobat, Carmen Mihaela, additional, Birkun, Alexei, additional, Kaluzhenina, Anna, additional, Almotairi, Abdullah, additional, Bukhary, Zakeya Abdulbaqi Ali, additional, Edathodu, Jameela, additional, Fathy, Amal, additional, Mushira Abdulaziz Enani, Abdullah, additional, Eltayeb Mohamed, Nazik, additional, Ulhadi Memon, Jawed, additional, Bella, Abdelhaleem, additional, Bogdanovic, Nada, additional, Milenkovic, Branislava, additional, Pesut, Dragica, additional, Borderìas, Luis, additional, Bordon Garcia, Noel Manuel, additional, Cabello Alarcón, Hugo, additional, Cilloniz, Catia, additional, Torres, Antoni, additional, Diaz-Brito, Vicens, additional, Casas, Xavier, additional, Encabo González, Alicia, additional, Fernández-Almira, Maria Luisa, additional, Gallego, Miguel, additional, Gaspar-GarcÍa, Inmaculada, additional, González del Castillo, Juan, additional, Javaloyes Victoria, Patricia, additional, Laserna Martínez, Elena, additional, Malo de Molina, Rosa, additional, Marcos, Pedro J, additional, Menéndez, Rosario, additional, Pando-Sandoval, Ana, additional, Prat Aymerich, Cristina, additional, Lacoma de la Torre, Alicia, additional, García-Olivé, Ignasi, additional, Rello, Jordi, additional, Moyano, Silvia, additional, Sanz, Francisco, additional, Sibila, Oriol, additional, Rodrigo-Troyano, Ana, additional, Solé-Violán, Jordi, additional, Uranga, Ane, additional, van Boven, Job FM, additional, Vendrell Torra, Ester, additional, Pujol, Jordi Almirall, additional, Feldman, Charles, additional, Kee Yum, Ho, additional, Fiogbe, Arnauld Attannon, additional, Yangui, Ferdaous, additional, Bilaceroglu, Semra, additional, Dalar, Levent, additional, Yilmaz, Ufuk, additional, Bogomolov, Artemii, additional, Elahi, Naheed, additional, Dhasmana, Devesh J, additional, Feneley, Andrew, additional, Ions, Rhiannon, additional, Skeemer, Julie, additional, Woltmann, Gerrit, additional, Hancock, Carole, additional, Hill, Adam T, additional, Rudran, Banu, additional, Ruiz-Buitrago, Silvia, additional, Campbell, Marion, additional, Whitaker, Paul, additional, Youzguin, Alexander, additional, Singanayagam, Anika, additional, Allen, Karen S, additional, Brito, Veronica, additional, Dietz, Jessica, additional, Dysart, Claire E, additional, Kellie, Susan M, additional, Franco-Sadud, Ricardo A, additional, Meier, Garnet, additional, Gaga, Mina, additional, Holland, Thomas L, additional, Bergin, Stephen P, additional, Kheir, Fayez, additional, Landmeier, Mark, additional, Lois, Manuel, additional, Nair, Girish B, additional, Patel, Hemali, additional, Reyes, Katherine, additional, Rodriguez-Cintron, William, additional, Saito, Shigeki, additional, Noda, Julio, additional, Hinojosa, Cecilia I, additional, Levine, Stephanie M, additional, Angel, Luis F, additional, Anzueto, Antonio, additional, Whitlow, K Scott, additional, Hipskind, John, additional, Sukhija, Kunal, additional, Totten, Vicken, additional, Wunderink, Richard G, additional, Shah, Ray D, additional, Mateyo, Kondwelani John, additional, Noriega, Lorena, additional, Alvarado, Ezequiel, additional, Aman, Mohamed, additional, and Labra, Lucía, additional
Published: 2016
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22. Lung Injury Caused by All-Trans-Retinoic Acid in the Treatment of Acute Promyelocytic Leukemia

Author: Ariza-Prota, Miguel, primary, Pando-Sandoval, Ana, additional, and García-Clemente, Marta, additional
Published: 2016
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23. Afectación pulmonar por ácido transretinoico en el tratamiento de la leucemia promielocítica aguda

Author: Ariza-Prota, Miguel, primary, Pando-Sandoval, Ana, additional, and García-Clemente, Marta, additional
Published: 2016
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24. Miliary Tuberculosis With Vertebral Involvement (Pott's Disease)

Author: Ariza-Prota, Miguel, primary, Pando-Sandoval, Ana, additional, and García-Clemente, Marta, additional
Published: 2016
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25. Tuberculosis miliar con afectación vertebral (mal de Pott)

Author: Ariza-Prota, Miguel, primary, Pando-Sandoval, Ana, additional, and García-Clemente, Marta, additional
Published: 2016
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26. Community-AcquiredMoraxella catarrhalisBacteremic Pneumonia: Two Case Reports and Review of the Literature

Author: Ariza-Prota, Miguel Angel, primary, Pando-Sandoval, Ana, additional, García-Clemente, Marta, additional, Fole-Vázquez, David, additional, and Casan, Pere, additional
Published: 2016
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27. Poncet's disease mimicking rheumatoid arthritis in a patient with suspected Crohn's disease

Author: Ariza‐Prota, Miguel, primary, Pando‐Sandoval, Ana, additional, García‐Clemente, Marta, additional, and Casan, Pere, additional
Published: 2015
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28. Community-acquired bacteremic Streptomyces atratus pneumonia in an immunocompetent adult: a case report

Author: Ariza-Prota, Miguel Angel, primary, Pando-Sandoval, Ana, additional, Fole-Vázquez, David, additional, García-Clemente, Marta, additional, Budiño, Teresa, additional, and Casan, Pere, additional
Published: 2015
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29. Amiloidosis traqueobronquial: diagnóstico, tratamiento y evolución en 5 casos

Author: Pando Sandoval, Ana, primary, Ariza Prota, Miguel Angel, additional, García Clemente, Marta, additional, and Casan, Pere, additional
Published: 2015
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30. Air embolism: a complication of computed tomography‐guided transthoracic needle biopsy

Author: Pando Sandoval, Ana, primary, Ariza Prota, Miguel Angel, additional, García Clemente, Marta, additional, Prieto, Amador, additional, Fole Vázquez, David, additional, and Casán, Pere, additional
Published: 2015
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31. Community-Acquired Pneumonia and Empyema Caused byCitrobacter koseriin an Immunocompetent Patient

Author: Ariza-Prota, Miguel Angel, primary, Pando-Sandoval, Ana, additional, García-Clemente, Marta, additional, Fernández, Ramón, additional, and Casan, Pere, additional
Published: 2015
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32. Desmoplastic small round cell tumor of the lung: A case report and literature review

Author: Ariza-Prota, Miguel Angel, primary, Pando-Sandoval, Ana, additional, Fole-Vázquez, David, additional, and Casan, Pere, additional
Published: 2015
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33. Finger-in-Glove Sign in Congenital Bronchial Atresia

Author: Ariza-Prota, Miguel, primary, Jarilla, José Luis Diez, additional, Prieto, Amador, additional, Pando-Sandoval, Ana, additional, and Casan, Pere, additional
Published: 2015
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34. Flavimonas oryzihabitans bacteremia and concomitant pleural tuberculosis

Author: Pando-Sandoval, Ana, primary, Angel-Ariza, Miguel, additional, Garcia-Clemente, Marta, additional, Buchelli-Ramirez, Herminia, additional, Madrid, Claudia, additional, Martínez-Zapico, Aleida, additional, and Casan, Pere, additional
Published: 2014
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35. Pleural Effusion Due to Streptococcus milleri: Case Descriptions

Author: Madrid-Carbajal, Claudia Janeth, primary, Molinos, Luis, additional, García-Clemente, Marta, additional, Pando-Sandoval, Ana, additional, Fleites, Ana, additional, and Casan-Clarà, Pere, additional
Published: 2014
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36. Descripción de casos de derrame pleural secundario a Streptococcus milleri

Author: Madrid-Carbajal, Claudia Janeth, primary, Molinos, Luis, additional, García-Clemente, Marta, additional, Pando-Sandoval, Ana, additional, Fleites, Ana, additional, and Casan-Clarà, Pere, additional
Published: 2014
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37. T-Cell Profiling and the Immunodiagnosis of Latent Tuberculosis Infection in Patients with Inflammatory Bowel Disease

Author: Arias-Guillén, Miguel, primary, Riestra, Sabino, additional, de Francisco, Ruth, additional, Palacios, Juan José, additional, Belda, José, additional, Escalante, Patricio, additional, Pérez-Martínez, Isabel, additional, Molinos, Luis M., additional, Garcia-Clemente, Marta, additional, Pando-Sandoval, Ana, additional, Rodrigo, Luis, additional, Prieto, Amador, additional, Martínez-Camblor, Pablo, additional, Losada, Ana, additional, and Casan, Pere, additional
Published: 2014
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38. Pneumothorax as Atypical Presentation of Bronchial Carcinoid

Author: Madrid-Carbajal, Claudia J., primary, García-Clemente, Marta M., additional, Gutiérrez-Rodríguez, Margarita, additional, Pando-Sandoval, Ana, additional, Álvarez-Santín, Laura, additional, and Casan-Clarà, Pere, additional
Published: 2013
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39. Tumor carcinoide bronquial: análisis de 60 pacientes

Author: Madrid-Carbajal, Claudia, primary, García-Clemente, Marta, additional, Pando-Sandoval, Ana, additional, Cubillas Martín, Hugo, additional, González-Budiño, Teresa, additional, and Casan-Clarà, Pere, additional
Published: 2013
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40. Poncet's disease mimicking rheumatoid arthritis in a patient with suspected Crohn's disease.

Author: Ariza‐Prota, Miguel, Pando‐Sandoval, Ana, García‐Clemente, Marta, and Casan, Pere
Subjects: *RHEUMATOID arthritis, *ARTHRITIS, *AUTOIMMUNE diseases, *CROHN'S disease, *INFLAMMATORY bowel diseases
Abstract: Key Clinical Message Poncet's disease is a rarely reported entity with an unknown pathogenesis. However, because it has a very favorable prognosis with antituberculosis drugs, we believe it should be considered as a differential diagnosis for patients with fever and polyarthritis of unknown cause, particularly if active tuberculosis is suspected. [ABSTRACT FROM AUTHOR]
Published: 2016
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41. Community-acquired bacteremic Streptomyces atratus pneumonia in animmunocompetent adult: a case report.

Author: Ariza-Prota, Miguel Angel, Pando-Sandoval, Ana, Fole-Vázquez, David, García-Clemente, Marta, Budiño, Teresa, and Casan, Pere
Subjects: *STREPTOMYCES, *GRAM-positive bacteria, *STREPTOMYCIN, *PNEUMONIA, *LUNG diseases, *PNEUMONIA diagnosis, *ANTIBIOTICS, *BODY fluids, *BRONCHOSCOPY, *CORYNEBACTERIACEAE, *ENZYME inhibitors, *IMMUNE response, *IMMUNOCOMPETENT cells, *QUINOLONE antibacterial agents, *COMMUNITY-acquired infections, *TREATMENT effectiveness, *SEQUENCE analysis, *IMIPENEM, *DIAGNOSIS
Abstract: Introduction: Streptomyces spp. are aerobic, Gram-positive bacteria of the order Actinomycetales, known for their ability to produce antimicrobial molecules such as streptomycin. Pneumonia due to Streptomyces is considered to be rare and limited to immunocompromised patients. Streptomyces spp. are only rarely associated with invasive systemic infections. To our knowledge, we report the first documented case of community-acquired Streptomyces atratus bacteremic pneumonia in an immunocompetent patient.Case Presentation: We describe a case of Streptomyces atratus bacteremic pneumonia in an otherwise healthy, 77-year-old Spanish man. Streptomyces identified by 16S ribosomal RNA sequencing grew in multiple blood cultures and bronchoalveolar lavage cultures. The infection resolved completely after treatment with imipenem and amoxicillin/clavulanic acid for 2 months.Conclusions: The majority of cases reported in the literature make reference to the difficulty of determining the pathogenic role of Streptomyces spp. Usually considered a contaminant, the pathogenic role of Streptomyces spp. is easier to confirm when the species is isolated from a catheter tip and, in the case of blood cultures, in more than one sample with a high count of colonies. To our knowledge, we report the first documented case of Streptomyces atratus bacteremic pneumonia in an immunocompetent patient. As the experience is limited, further studies are needed to better understand the interpretation of the isolates of the genus Streptomyces; the predisposing factors for infection; and the course, treatment, and evolution of these infections. [ABSTRACT FROM AUTHOR]
Published: 2015
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42. Community-Acquired Moraxella catarrhalis Bacteremic Pneumonia: Two Case Reports and Review of the Literature

Author: Angel Ariza-Prota, Miguel, Pando-Sandoval, Ana, García-Clemente, Marta, Fole-Vázquez, David, and Casan, Pere
Abstract: Moraxella (formerly Branhamella) catarrhalis was discovered at the end of the nineteenth century, and for many decades it was considered to be a harmless commensal of the upper respiratory tract. It is a Gram-negative, aerobic diplococcus considered to be the third most common pathogen isolated in childhood sinusitis and otitis media and in adult chronic lower respiratory disease, as well as an etiological agent of pneumonia in immunosuppressed patients or those with chronic obstructive pulmonary disease. Moraxella catarrhalis pneumonia is rarely associated with bacteremia. Here, we present two cases of community-acquired Moraxella catarrhalis bacteremic pneumonia.
Published: 2016
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43. Community-Acquired Pneumonia and Empyema Caused by Citrobacter koseri in an Immunocompetent Patient

Author: Angel Ariza-Prota, Miguel, Pando-Sandoval, Ana, García-Clemente, Marta, Fernández, Ramón, and Casan, Pere
Abstract: Citrobacter species, belonging to the family Enterobacteriaceae, are environmental organisms commonly found in soil, water, and the intestinal tracts of animals and humans. Citrobacter koseri is known to be an uncommon but serious cause of both sporadic and epidemic septicemia and meningitis in neonates and young infants. Most cases reported have occurred in immunocompromised hosts. The infections caused by Citrobacter are difficult to treat with usual broad spectrum antibiotics owing to rapid generation of mutants and have been associated with high death rates in the past. We believe this is the first case described in the literature of a community-acquired pneumonia and empyema caused by Citrobacter koseri in an immunocompetent adult patient.
Published: 2015
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44. Aspiration Risk Factors, Microbiology, and Empiric Antibiotics for Patients Hospitalized With Community-Acquired Pneumonia

Author: Judith Marin-Corral, Sergi Pascual-Guardia, Francesco Amati, Stefano Aliberti, Joan R Masclans, Nilam Soni, Alejandro Rodriguez, Oriol Sibila, Francisco Sanz, Giovanni Sotgiu, Antonio Anzueto, Katerina Dimakou, Roberta Petrino, Ewoudt van de Garde, Marcos I Restrepo, GLIMP investigators, Patricia Karina Aruj, Silvia Attorri, Enrique Barimboim, Juan Pablo Caeiro, María I Garzón, Victor Hugo Cambursano, V H Dr Cazaux A Adrian Ceccato, Julio Chertcoff, Florencia Lascar, Fernando Di Tulio, Ariel Cordon Díaz, Lautaro de Vedia, Maria Cristina Ganaha, Sandra Lambert, Gustavo Lopardo, Carlos M Luna, Alessio Gerardo Malberti, Nora Morcillo, Silvina Tartara, Claudia Pensotti, Betiana Pereyra, Pablo Gustavo Scapellato, Juan Pablo Stagnaro, Sonali Shah, Felix Lötsch, Florian Thalhammer, Kurt Anseeuw, Camille A Francois, Eva Van Braeckel, Jean Louis Vincent, Marcel Zannou Djimon, Jules Bashi, Roger Dodo, Simone Aranha Nouér, Peter Chipev, Milena Encheva, Darina Miteva, Diana Petkova, Adamou Dodo Balkissou, Eric Walter Pefura Yone, Bertrand Hugo Mbatchou Ngahane, Ning Shen, Jin-Fu Xu, Carlos Andres Bustamante Rico, Ricardo Buitrago, Fernando Jose Pereira Paternina, Jean-Marie Kayembe Ntumba, Vesna Vladic Carevic, Marko Jakopovic, Mateja Jankovic, Zinka Matkovic, Ivan Mitrecic, Marie-Laure Bouchy Jacobsson, Anette Bro Christensen, Uffe Christian Heitmann Bødtger, Christian Niels Meyer, Andreas Vestergaard Jensen, Gertrud Baunbæk-Knudsen, Pelle Trier Petersen, Stine Andersen, Ibrahim El-Said Abd El-Wahhab, Nesreen Elsayed Morsy, Hanaa Shafiek, Eman Sobh, Kedir Abdella Abdulsemed, Fabrice Bertrand, Christian Brun-Buisson, Etienne de Montmollin, Muriel Fartoukh, Jonathan Messika, Pierre Tattevin, Abdo Khoury, Bernard Ebruke, Michael Dreher, Martin Kolditz, Matthias Meisinger, Mathias W Pletz, Stefan Hagel, Jan Rupp, Tom Schaberg, Marc Spielmanns, Petra Creutz, Norton Suttorp, Beatrice Siaw-Lartey, Dimosthenis Papapetrou, Evdoxia Tsigou, Dimitrios Ampazis, Evangelos Kaimakamis, Mohit Bhatia, Raja Dhar, George D'Souza, Rajiv Garg, Parvaiz A Koul, P A Mahesh, B S Jayaraj, Kiran Vishnu Narayan, Hirennappa B Udnur, Shashi Bhaskara Krishnamurthy, Surya Kant, Rajesh Swarnakar, Sneha Limaye, Sundeep Salvi, Keihan Golshani, Vera M Keatings, Ignacio Martin-Loeches, Yasmin Maor, Jacob Strahilevitz, Paola Faverio, Salvatore Battaglia, Maria Carrabba, Piero Ceriana, Marco Confalonieri, Antonella d'Arminio Monforte, Bruno Del Prato, Marino De Rosa, Riccardo Fantini, Giuseppe Fiorentino, Maria Antonia Gammino, Francesco Menzella, Giuseppe Milani, Stefano Nava, Gerardo Palmiero, Barbra Gabrielli, Paolo Rossi, Claudio Sorino, Gundi Steinhilber, Alessandro Zanforlin, Ospedale San Luca, Fabio Franzetti, Manuela Carugati, Manuela Morosi, Elisa Monge, Mauro Carone, Vincenzo Patella, Simone Scarlata, Andrea Comel, Kiyoyasu Kurahashi, Zeina Aoun Bacha, Daniel Barajas Ugalde, Omar Ceballos Zuñiga, José F Villegas, Milic Medenica, Deebya Raj Mihsra, Poojan Shrestha, Elliott Ridgeon, Babatunde Ishola Awokola, Ogonna N O Adefuye Bolanle Olufunlola, Segaolu Olumide, Kingsley N Ukwaja, Muhammad Irfan, Lukasz Minarowski, Skoczyński Szymon, Felipe Froes, Pedro Leuschner, Mariana Meireles, Cláudia Ferrão, João Neves, Abel Salazar, Sofia B Ravara, Victoria Brocovschii, Doina Rusu, Cristina Toma, Daniela Chirita, Carmen Mihaela Dorobat, Alexei Birkun, Anna Kaluzhenina, Abdullah Almotairi, Zakeya Abdulbaqi Ali Bukhary, Jameela Edathodu, Amal Fathy, Abdullah Mushira Abdulaziz Enani, Nazik Eltayeb Mohamed, Jawed Ulhadi Memon, Abdelhaleem Bella, Serbia Nada Bogdanović, Branislava Milenkovic, Dragica Pesut, Luis Borderìas, Noel Manuel Bordon Garcia, Hugo Cabello Alarcón, Catia Cilloniz, Antoni Torres, Vicens Diaz-Brito, Xavier Casas, Alicia Encabo González, Maria Luisa Fernández-Almira, Medicina Interna, Miguel Gallego, Inmaculada Gaspar-GarcÍa, Juan González Del Castillo, Patricia Javaloyes Victoria, Elena Laserna Martínez, Rosa Malo de Molina, Pedro J Marcos, Rosario Menéndez, Ana Pando-Sandoval, Cristina Prat Aymerich, Alicia Lacoma de la Torre, Ignasi García-Olivé, Jordi Rello, Silvia Moyano, Ana Rodrigo-Troyano, Jordi Solé-Violán, Ane Uranga, Job Fm van Boven, Ester Vendrell Torra, Jordi Almirall Pujol, Charles Feldman, Ho Kee Yum, Inje Univ Arnauld Attannon Fiogbe, Ferdaous Yangui, Semra Bilaceroglu, Izmir Dr Levent Dalar, Ufuk Yilmaz, Artemii Bogomolov, Naheed Elahi, Devesh J Dhasmana, Andrew Feneley, Adam T Hill, Banu Rudran, Silvia Ruiz-Buitrago, Marion Campbell, Paul Whitaker, Alexander Youzguin, Anika Singanayagam, C Hancock, David Villafuerte, Karen S Allen, Veronica Brito, Jessica Dietz, Claire E Dysart, Susan M Kellie, Clement J Ricardo A Franco-Sadud, Garnet Meier, Mina Gaga, Thomas L Holland, Stephen P Bergin, Fayez Kheir, Mark Landmeier, Manuel Lois, Girish B Nair, Hemali Patel, Katherine Reyes, William Rodriguez-Cintron, Shigeki Saito, Julio Noda, Cecilia I Hinojosa, Stephanie M Levine, Luis F Reyes, Luis F Angel, K Scott Whitlow, John Hipskind, Kunal Sukhija, Vicken Totten, Richard G Wunderink, Ray D Shah, Kondwelani John Mateyo, Lorena Noriega, Ezequiel Alvarado, Mohamed Aman, Lucía Labra, Marin-Corral J., Pascual-Guardia S., Amati F., Aliberti S., Masclans J.R., Soni N., Rodriguez A., Sibila O., Sanz F., Sotgiu G., Anzueto A., Dimakou K., Petrino R., van de Garde E., Restrepo M.I., Aruj P.K., Attorri S., Barimboim E., Caeiro J.P., Garzon M.I., Cambursano V.H., Adrian Ceccato V.H.D.C.A., Chertcoff J., Lascar F., Di Tulio F., Diaz A.C., de Vedia L., Ganaha M.C., Lambert S., Lopardo G., Luna C.M., Malberti A.G., Morcillo N., Tartara S., Pensotti C., Pereyra B., Scapellato P.G., Stagnaro J.P., Shah S., Lotsch F., Thalhammer F., Anseeuw K., Francois C.A., Van Braeckel E., Vincent J.L., Djimon M.Z., Bashi J., Dodo R., Nouer S.A., Chipev P., Encheva M., Miteva D., Petkova D., Balkissou A.D., Pefura Yone E.W., Mbatchou Ngahane B.H., Shen N., Xu J.-F., Bustamante Rico C.A., Buitrago R., Pereira Paternina F.J., Kayembe Ntumba J.-M., Carevic V.V., Jakopovic M., Jankovic M., Matkovic Z., Mitrecic I., Bouchy Jacobsson M.-L., Christensen A.B., Heitmann Bodtger U.C., Meyer C.N., Jensen A.V., Baunbaek-knudsen G., Petersen P.T., Andersen S., El-Said Abd El-Wahhab I., Morsy N.E., Shafiek H., Sobh E., Abdulsemed K.A., Bertrand F., Brun-Buisson C., de Montmollin E., Fartoukh M., Messika J., Tattevin P., Khoury A., Ebruke B., Dreher M., Kolditz M., Meisinger M., Pletz M.W., Hagel S., Rupp J., Schaberg T., Spielmanns M., Creutz P., Suttorp N., Siaw-Lartey B., Papapetrou D., Tsigou E., Ampazis D., Kaimakamis E., Bhatia M., Dhar R., D'Souza G., Garg R., Koul P.A., Mahesh P.A., Jayaraj B.S., Narayan K.V., Udnur H.B., Krishnamurthy S.B., Kant S., Swarnakar R., Limaye S., Salvi S., Golshani K., Keatings V.M., Martin-Loeches I., Maor Y., Strahilevitz J., Faverio P., Battaglia S., Carrabba M., Ceriana P., Confalonieri M., Monforte A.D., Del Prato B., De Rosa M., Fantini R., Fiorentino G., Gammino M.A., Menzella F., Milani G., Nava S., Palmiero G., Gabrielli B., Rossi P., Sorino C., Steinhilber G., Zanforlin A., San Luca O., Franzetti F., Carugati M., Morosi M., Monge E., Carone M., Patella V., Scarlata S., Comel A., Kurahashi K., Bacha Z.A., Ugalde D.B., Zuniga O.C., Villegas J.F., Medenica M., Mihsra D.R., Shrestha P., Ridgeon E., Awokola B.I., Adefuye Bolanle Olufunlola O.N.O., Olumide S., Ukwaja K.N., Irfan M., Minarowski L., Szymon S., Froes F., Leuschner P., Meireles M., Ferrao C., Neves J., Abel Salazar, Ravara S.B., Brocovschii V., Rusu D., Toma C., Chirita D., Dorobat C.M., Birkun A., Kaluzhenina A., Almotairi A., Ali Bukhary Z.A., Edathodu J., Fathy A., Abdulaziz Enani A.M., Mohamed N.E., Memon J.U., Bella A., Bogdanovic S.N., Milenkovic B., Pesut D., Borderias L., Bordon Garcia N.M., Alarcon H.C., Cilloniz C., Torres A., Diaz-Brito V., Casas X., Gonzalez A.E., Fernandez-Almira M.L., Interna M., Gallego M., Gaspar-GarcIa I., Gonzalez del Castillo J., Victoria P.J., Martinez E.L., Malo de Molina R., Marcos P.J., Menendez R., Pando-Sandoval A., Aymerich C.P., Lacoma de la Torre A., Garcia-Olive I., Rello J., Moyano S., Rodrigo-Troyano A., Sole-Violan J., Uranga A., van Boven J.F., Torra E.V., Pujol J.A., Feldman C., Yum H.K., Arnauld Attannon Fiogbe I.U., Yangui F., Bilaceroglu S., Levent Dalar I.D., Yilmaz U., Bogomolov A., Elahi N., Dhasmana D.J., Feneley A., Hill A.T., Rudran B., Ruiz-Buitrago S., Campbell M., Whitaker P., Youzguin A., Singanayagam A., Hancock C., Villafuerte D., Allen K.S., Brito V., Dietz J., Dysart C.E., Kellie S.M., Ricardo A. Franco-Sadud C.J., Meier G., Gaga M., Holland T.L., Bergin S.P., Kheir F., Landmeier M., Lois M., Nair G.B., Patel H., Reyes K., Rodriguez-Cintron W., Saito S., Noda J., Hinojosa C.I., Levine S.M., Reyes L.F., Angel L.F., Whitlow K.S., Hipskind J., Sukhija K., Totten V., Wunderink R.G., Shah R.D., Mateyo K.J., Noriega L., Alvarado E., Aman M., Labra L., Marin-Corral, Judith, Pascual-Guardia, Sergi, Amati, Francesco, Aliberti, Stefano, R Masclans, Joan, Soni, Nilam, Rodriguez, Alejandro, Sibila, Oriol, Sanz, Francisco, Sotgiu, Giovanni, Anzueto, Antonio, Dimakou, Katerina, Petrino, Roberta, van de Garde, Ewoudt, I Restrepo, Marco, Investigators, Glimp, Karina Aruj, Patricia, Attorri, Silvia, Barimboim, Enrique, Pablo Caeiro, Juan, I Garzón, María, Hugo Cambursano, Victor, A Adrian Ceccato, V H Dr Cazaux, Chertcoff, Julio, Lascar, Florencia, Di Tulio, Fernando, Cordon Díaz, Ariel, de Vedia, Lautaro, Cristina Ganaha, Maria, Lambert, Sandra, Lopardo, Gustavo, M Luna, Carlo, Gerardo Malberti, Alessio, Morcillo, Nora, Tartara, Silvina, Pensotti, Claudia, Pereyra, Betiana, Gustavo Scapellato, Pablo, Pablo Stagnaro, Juan, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Anseeuw, Kurt, A Francois, Camille, Van Braeckel, Eva, Louis Vincent, Jean, Zannou Djimon, Marcel, Bashi, Jule, Dodo, Roger, Aranha Nouér, Simone, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Dodo Balkissou, Adamou, Walter Pefura Yone, Eric, Hugo Mbatchou Ngahane, Bertrand, Shen, Ning, Xu, Jin-Fu, Andres Bustamante Rico, Carlo, Buitrago, Ricardo, Jose Pereira Paternina, Fernando, Kayembe Ntumba, Jean-Marie, Vladic Carevic, Vesna, Jakopovic, Marko, Jankovic, Mateja, Matkovic, Zinka, Mitrecic, Ivan, Bouchy Jacobsson, Marie-Laure, Bro Christensen, Anette, Christian Heitmann Bødtger, Uffe, Niels Meyer, Christian, Vestergaard Jensen, Andrea, Baunbæk-Knudsen, Gertrud, Trier Petersen, Pelle, Andersen, Stine, El-Said Abd El-Wahhab, Ibrahim, Elsayed Morsy, Nesreen, Shafiek, Hanaa, Sobh, Eman, Abdella Abdulsemed, Kedir, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthia, W Pletz, Mathia, Hagel, Stefan, Rupp, Jan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Papapetrou, Dimostheni, Tsigou, Evdoxia, Ampazis, Dimitrio, Kaimakamis, Evangelo, Bhatia, Mohit, Dhar, Raja, D'Souza, George, Garg, Rajiv, A Koul, Parvaiz, A Mahesh, P, S Jayaraj, B, Vishnu Narayan, Kiran, B Udnur, Hirennappa, Bhaskara Krishnamurthy, Shashi, Kant, Surya, Swarnakar, Rajesh, Limaye, Sneha, Salvi, Sundeep, Golshani, Keihan, M Keatings, Vera, Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Faverio, Paola, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, d'Arminio Monforte, Antonella, Del Prato, Bruno, De Rosa, Marino, Fantini, Riccardo, Fiorentino, Giuseppe, Antonia Gammino, Maria, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, San Luca, Ospedale, Franzetti, Fabio, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Aoun Bacha, Zeina, Barajas Ugalde, Daniel, Ceballos Zuñiga, Omar, F Villegas, José, Medenica, Milic, Raj Mihsra, Deebya, Shrestha, Poojan, Ridgeon, Elliott, Ishola Awokola, Babatunde, O Adefuye Bolanle Olufunlola, Ogonna N, Olumide, Segaolu, N Ukwaja, Kingsley, Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczyński, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Salazar, Abel, B Ravara, Sofia, Brocovschii, Victoria, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Mihaela Dorobat, Carmen, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Abdulbaqi Ali Bukhary, Zakeya, Edathodu, Jameela, Fathy, Amal, Mushira Abdulaziz Enani, Abdullah, Eltayeb Mohamed, Nazik, Ulhadi Memon, Jawed, Bella, Abdelhaleem, Nada Bogdanović, Serbia, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Lui, Manuel Bordon Garcia, Noel, Cabello Alarcón, Hugo, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicen, Casas, Xavier, Encabo González, Alicia, Luisa Fernández-Almira, Maria, Interna, Medicina, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, González Del Castillo, Juan, Javaloyes Victoria, Patricia, Laserna Martínez, Elena, Malo de Molina, Rosa, J Marcos, Pedro, Menéndez, Rosario, Pando-Sandoval, Ana, Prat Aymerich, Cristina, Lacoma de la Torre, Alicia, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, Fm van Boven, Job, Vendrell Torra, Ester, Almirall Pujol, Jordi, Feldman, Charle, Kee Yum, Ho, Univ Arnauld Attannon Fiogbe, Inje, Yangui, Ferdaou, Bilaceroglu, Semra, Dr Levent Dalar, Izmir, Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, J Dhasmana, Devesh, Feneley, Andrew, T Hill, Adam, Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Hancock, C, Villafuerte, David, S Allen, Karen, Brito, Veronica, Dietz, Jessica, E Dysart, Claire, M Kellie, Susan, A Franco-Sadud, Clement J Ricardo, Meier, Garnet, Gaga, Mina, L Holland, Thoma, P Bergin, Stephen, Kheir, Fayez, Landmeier, Mark, Lois, Manuel, B Nair, Girish, Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Noda, Julio, I Hinojosa, Cecilia, M Levine, Stephanie, F Reyes, Lui, F Angel, Lui, Scott Whitlow, K, Hipskind, John, Sukhija, Kunal, Totten, Vicken, G Wunderink, Richard, D Shah, Ray, John Mateyo, Kondwelani, Noriega, Lorena, Alvarado, Ezequiel, Aman, Mohamed, Labra, Lucía, Marin-Corral, J, Pascual-Guardia, S, Amati, F, Aliberti, S, Masclans, J, Soni, N, Rodriguez, A, Sibila, O, Sanz, F, Sotgiu, G, Anzueto, A, Dimakou, K, Petrino, R, van de Garde, E, Restrepo, M, Aruj, P, Attorri, S, Barimboim, E, Caeiro, J, Garzon, M, Cambursano, V, Adrian Ceccato, V, Chertcoff, J, Lascar, F, Di Tulio, F, Diaz, A, de Vedia, L, Ganaha, M, Lambert, S, Lopardo, G, Luna, C, Malberti, A, Morcillo, N, Tartara, S, Pensotti, C, Pereyra, B, Scapellato, P, Stagnaro, J, Shah, S, Lotsch, F, Thalhammer, F, Anseeuw, K, Francois, C, Van Braeckel, E, Vincent, J, Djimon, M, Bashi, J, Dodo, R, Nouer, S, Chipev, P, Encheva, M, Miteva, D, Petkova, D, Balkissou, A, Pefura Yone, E, Mbatchou Ngahane, B, Shen, N, Xu, J, Bustamante Rico, C, Buitrago, R, Pereira Paternina, F, Kayembe Ntumba, J, Carevic, V, Jakopovic, M, Jankovic, M, Matkovic, Z, Mitrecic, I, Bouchy Jacobsson, M, Christensen, A, Heitmann Bodtger, U, Meyer, C, Jensen, A, Baunbaek-knudsen, G, Petersen, P, Andersen, S, El-Said Abd El-Wahhab, I, Morsy, N, Shafiek, H, Sobh, E, Abdulsemed, K, Bertrand, F, Brun-Buisson, C, de Montmollin, E, Fartoukh, M, Messika, J, Tattevin, P, Khoury, A, Ebruke, B, Dreher, M, Kolditz, M, Meisinger, M, Pletz, M, Hagel, S, Rupp, J, Schaberg, T, Spielmanns, M, Creutz, P, Suttorp, N, Siaw-Lartey, B, Papapetrou, D, Tsigou, E, Ampazis, D, Kaimakamis, E, Bhatia, M, Dhar, R, D'Souza, G, Garg, R, Koul, P, Mahesh, P, Jayaraj, B, Narayan, K, Udnur, H, Krishnamurthy, S, Kant, S, Swarnakar, R, Limaye, S, Salvi, S, Golshani, K, Keatings, V, Martin-Loeches, I, Maor, Y, Strahilevitz, J, Faverio, P, Battaglia, S, Carrabba, M, Ceriana, P, Confalonieri, M, Monforte, A, Del Prato, B, De Rosa, M, Fantini, R, Fiorentino, G, Gammino, M, Menzella, F, Milani, G, Nava, S, Palmiero, G, Gabrielli, B, Rossi, P, Sorino, C, Steinhilber, G, Zanforlin, A, San Luca, O, Franzetti, F, Carugati, M, Morosi, M, Monge, E, Carone, M, Patella, V, Scarlata, S, Comel, A, Kurahashi, K, Bacha, Z, Ugalde, D, Zuniga, O, Villegas, J, Medenica, M, Mihsra, D, Shrestha, P, Ridgeon, E, Awokola, B, Adefuye Bolanle Olufunlola, O, Olumide, S, Ukwaja, K, Irfan, M, Minarowski, L, Szymon, S, Froes, F, Leuschner, P, Meireles, M, Ferrao, C, Neves, J, Abel, S, Ravara, S, Brocovschii, V, Rusu, D, Toma, C, Chirita, D, Dorobat, C, Birkun, A, Kaluzhenina, A, Almotairi, A, Ali Bukhary, Z, Edathodu, J, Fathy, A, Abdulaziz Enani, A, Mohamed, N, Memon, J, Bella, A, Bogdanovic, S, Milenkovic, B, Pesut, D, Borderias, L, Bordon Garcia, N, Alarcon, H, Cilloniz, C, Torres, A, Diaz-Brito, V, Casas, X, Gonzalez, A, Fernandez-Almira, M, Interna, M, Gallego, M, Gaspar-GarcIa, I, Gonzalez del Castillo, J, Victoria, P, Martinez, E, Malo de Molina, R, Marcos, P, Menendez, R, Pando-Sandoval, A, Aymerich, C, Lacoma de la Torre, A, Garcia-Olive, I, Rello, J, Moyano, S, Rodrigo-Troyano, A, Sole-Violan, J, Uranga, A, van Boven, J, Torra, E, Pujol, J, Feldman, C, Yum, H, Arnauld Attannon Fiogbe, I, Yangui, F, Bilaceroglu, S, Levent Dalar, I, Yilmaz, U, Bogomolov, A, Elahi, N, Dhasmana, D, Feneley, A, Hill, A, Rudran, B, Ruiz-Buitrago, S, Campbell, M, Whitaker, P, Youzguin, A, Singanayagam, A, Villafuerte, D, Allen, K, Brito, V, Dietz, J, Dysart, C, Kellie, S, Ricardo, A, Meier, G, Gaga, M, Holland, T, Bergin, S, Kheir, F, Landmeier, M, Lois, M, Nair, G, Patel, H, Reyes, K, Rodriguez-Cintron, W, Saito, S, Noda, J, Hinojosa, C, Levine, S, Reyes, L, Angel, L, Whitlow, K, Hipskind, J, Sukhija, K, Totten, V, Wunderink, R, Shah, R, Mateyo, K, Noriega, L, Alvarado, E, Aman, M, and Labra, L
Subjects: Male, Pulmonary and Respiratory Medicine, medicine.drug_class, Aspiration risk, Antibiotics, Nursing home resident, Settore MED/10 - Malattie Dell'Apparato Respiratorio, Critical Care and Intensive Care Medicine, Microbiology, anaerobic, aspiration, bacteria, pneumonia, risk factors, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Community-acquired pneumonia, Taverne, Anti-Bacterial Agent, medicine, Humans, Community-Acquired Infection, 030212 general & internal medicine, Stroke, Aged, Aged, 80 and over, business.industry, Respiratory Aspiration, Middle Aged, medicine.disease, Antibiotic coverage, Anti-Bacterial Agents, Community-Acquired Infections, Hospitalization, Pneumonia, 030228 respiratory system, Risk factors, risk factor, Female, Underweight, medicine.symptom, business, Cardiology and Cardiovascular Medicine
Abstract: Background: Aspiration community-acquired pneumonia (ACAP) and community-acquired pneumonia (CAP) in patients with aspiration risk factors (AspRFs) are infections associated with anaerobes, but limited evidence suggests their pathogenic role. Research Question: What are the aspiration risk factors, microbiology patterns, and empiric anti-anaerobic use in patients hospitalized with CAP? Study Design and Methods: This is a secondary analysis of GLIMP, an international, multicenter, point-prevalence study of adults hospitalized with CAP. Patients were stratified into three groups: (1) ACAP, (2) CAP/AspRF+ (CAP with AspRF), and (3) CAP/AspRF- (CAP without AspRF). Data on demographics, comorbidities, microbiological results, and anti-anaerobic antibiotics were analyzed in all groups. Patients were further stratified in severe and nonsevere CAP groups. Results: We enrolled 2,606 patients with CAP, of which 193 (7.4%) had ACAP. Risk factors independently associated with ACAP were male, bedridden, underweight, a nursing home resident, and having a history of stroke, dementia, mental illness, and enteral tube feeding. Among non-ACAP patients, 1,709 (70.8%) had CAP/AspRF+ and 704 (29.2%) had CAP/AspRF-. Microbiology patterns including anaerobes were similar between CAP/AspRF-, CAP/AspRF+ and ACAP (0.0% vs 1.03% vs 1.64%). Patients with severe ACAP had higher rates of total gram-negative bacteria (64.3% vs 44.3% vs 33.3%, P =.021) and lower rates of total gram-positive bacteria (7.1% vs 38.1% vs 50.0%, P 50% in all groups) independent of AspRFs or ACAP received specific or broad-spectrum anti-anaerobic coverage antibiotics. Interpretation: Hospitalized patients with ACAP or CAP/AspRF+ had similar anaerobic flora compared with patients without aspiration risk factors. Gram-negative bacteria were more prevalent in patients with severe ACAP. Despite having similar microbiological flora between groups, a large proportion of CAP patients received anti-anaerobic antibiotic coverage.
Published: 2021

45. Is the long-term mortality similar in COVID-19 and community-acquired pneumonia?

Author: Méndez R, González-Jiménez P, Latorre A, Mengot N, Zalacain R, Ruiz LA, Serrano L, España PP, Uranga A, Cillóniz C, Hervás D, Torres A, Menéndez R, Pablo España P, Borderías L, Rajas O, Almirall J, Zalacaín R, Vendrell M, Bello S, Mir I, Morales C, Molinos L, Ferrer R, Briones M, Malo R, Sayago Reza I, Almonte Batista W, Moreno Galarraga L, Sibila Vidal O, Luis Rodríguez Hermosa J, Vargas Centanaro G, de Vega Sánchez B, Solís García E, Rodríguez Florez E, José M, Estaba C, Molina Molina M, Bordas J, Estela González Castro M, Badenes Bonet D, Domínguez Álvarez M, Pérez-Rodas EN, Marín Arguedas A, Román Bernal B, Estrada Trigueros G, Cuenca Peris S, Martín Royo M, Torres García M, Portillo Sánchez J, Lerenas Bernal F, Salome Ros Braquehais M, Alfonso García Guerra J, Dolores Martínez Pitarch M, Arroyo Fernández I, Guevara Velázquez V, Martínez Olondris P, Francisco Pereyra Barrionuevo M, Lázaro Sierra J, Clavería P, Luis Wangüemert Pérez A, Joel Ruiz Lacambra J, Fernández Ramos N, Guanche Dorta S, Macias Paredes A, de la Rosa Carrillo D, Palones Femenia E, Podzamczer Valls I, Peñacoba Toribio P, Muñoz Zara P, García García R, Del Mar Marrube Fernández M, Villar Aguilar L, de Jorge Domínguez Pazos S, Pereiro Brea T, Pando-Sandoval A, María García Clemente M, Alzueta Álvarez A, García Coya E, de Freitas González E, Pablo España Yandiola P, Uranga A, Raboso Moreno B, Panadero C, Abad A, Cano I, Pérez Orbis I, Gotera Rivera C, Ruiz Pérez C, Menéndez Villanueva R, Méndez R, Latorre A, González P, Ramírez Prieto T, Ángel Salvador Maya M, Valenzuela C, Cifrián Martínez JM, Marco Figueira Gonçalves J, Baeza Ruiz A, Expósito Marrero A, Gurbani N, Malo de Molina Ruiz R, Galdeano Lozano M, Villanueva Montes M, Toledo Pons N, Ramón Clar L, Esperanza Barrios A, Cejudo Ramos P, López Ramírez C, Gaboli M, Almadana Pacheco V, Eduard Barbé Illa F, Clara A, Gutiérrez González N, and Cabrera César E
Abstract: Introduction: There are no data on the association of type of pneumonia and long-term mortality by the type of pneumonia (COVID-19 or community-acquired pneumonia [CAP]) on long-term mortality after an adjustment for potential confounding variables. We aimed to assess the type of pneumonia and risk factors for long-term mortality in patients who were hospitalized in conventional ward and later discharged., Methods: Retrospective analysis of two prospective and multicentre cohorts of hospitalized patients with COVID-19 and CAP. The main outcome under study was 1-year mortality in hospitalized patients in conventional ward and later discharged. We adjusted a Bayesian logistic regression model to assess associations between the type of pneumonia and 1-year mortality controlling for confounders., Results: The study included a total of 1,693 and 2,374 discharged patients in the COVID-19 and CAP cohorts, respectively. Of these, 1,525 (90.1%) and 2,249 (95%) patients underwent analysis. Until 1-year follow-up, 69 (4.5%) and 148 (6.6%) patients from the COVID-19 and CAP cohorts, respectively, died ( p = 0.008). However, the Bayesian model showed a low probability of effect (PE) of finding relevant differences in long-term mortality between CAP and COVID-19 (odds ratio 1.127, 95% credibility interval 0.862-1.591; PE = 0.774)., Conclusion: COVID-19 and CAP have similar long-term mortality after adjusting for potential confounders., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Méndez, González-Jiménez, Latorre, Mengot, Zalacain, Ruiz, Serrano, España, Uranga, Cillóniz, Hervás, Torres, Menéndez, NEUMONAC and RECOVID.)
Published: 2023
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46. Indoor Radon Exposure and COPD, Synergic Association? A Multicentric, Hospital-Based Case-Control Study in a Radon-Prone Area.

Author: Ruano-Ravina A, Cameselle-Lago C, Torres-Durán M, Pando-Sandoval A, Dacal-Quintas R, Valdés-Cuadrado L, Hernández-Hernández J, Consuegra-Vanegas A, Tenes-Mayén JA, Varela-Lema L, Fernández-Villar A, Barros-Dios JM, and Pérez-Ríos M
Abstract: Background: COPD is a multifactorial disease which causes considerable mortality and morbidity worldwide. Previous studies assessing the possible relationship between indoor radon exposure and COPD have shown inconclusive results., Methods: A multicentric, hospital-based, case-control study was conducted in a Spanish radon-prone area. COPD cases were confirmed by spirometry and controls were selected due to trivial surgery or procedures not related to tobacco consumption. All participants had to have lived for at least 15 years in the same dwelling. Radon measurements were conducted individually in dwellings using alpha-track detectors. Results were obtained using multivariate logistic regression., Results: 189 cases and 747 controls took part. There was no significant association between residential radon concentrations and COPD onset with a OR of 1.12 (95%CI 0.41-3.06) for individuals exposed to more than 200Bq/m 3 compared to those exposed to less than 50Bq/m 3 . Heavy smokers seem to increase their COPD risk if exposed to higher radon concentrations vs those exposed to lower concentrations. There was a statistically significant synergy index between radon exposure and tobacco consumption, S-index 11.60 (95%CI 3.71-36.26). Indoor radon concentration was higher in never/light smokers with COPD compared to controls., Conclusions: No association between indoor radon and COPD has been observed. However, there might be some effect modification on the COPD risk in heavy smokers when high radon exposure is present. This is supported by the additive synergy observed. Also, a possible association between indoor radon and COPD onset in never and light smokers needs to be further studied., (Copyright © 2020 SEPAR. Publicado por Elsevier España, S.L.U. All rights reserved.)
Published: 2020
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47. [Bronchial carcinoid tumor: study of 60 patients].

Author: Madrid-Carbajal C, García-Clemente M, Pando-Sandoval A, Cubillas Martín H, González-Budiño T, and Casan-Clarà P
Subjects: Adult, Aged, Aged, 80 and over, Bronchial Neoplasms complications, Bronchial Neoplasms diagnosis, Bronchial Neoplasms pathology, Bronchial Neoplasms surgery, Bronchoscopy, Carcinoid Tumor complications, Carcinoid Tumor diagnosis, Carcinoid Tumor pathology, Carcinoid Tumor surgery, Cushing Syndrome etiology, Diagnostic Imaging, Female, Follow-Up Studies, Humans, Incidental Findings, Kaplan-Meier Estimate, Male, Malignant Carcinoid Syndrome etiology, Middle Aged, Pneumonectomy, Retrospective Studies, Spain epidemiology, Survival Rate, Young Adult, Bronchial Neoplasms epidemiology, Carcinoid Tumor epidemiology
Abstract: Background and Objective: To describe the casuistry of bronchial carcinoid tumor in the last 20 years in our hospital and determine survival after surgical treatment., Patients and Method: We retrospectively reviewed the medical records from January 1992 to June 2012 of patients diagnosed with carcinoid tumor by the pulmonary service., Results: Fifty-two patients (87%) had typical carcinoid and 8 (13%) atypical carcinoid. The mean age at diagnosis was 60 years (SD: 14.4). There was no relationship between consumption of tobacco and carcinoid tumor. Twenty-two per cent were asymptomatic radiographic finding (incidental finding) Three patients showed carcinoid syndrome and one patient had Cushing syndrome. There was a right dominance and the mean lesion size was between 2.1 and 5 cm. Nine per cent had lymph node involvement, predominantly in atypical carcinoid. Overall survival at 3.5 and 10 years was 94%, 86% and 82%. Survival at 5 years was 90% for typical and 86% for atypical and survival at 10 years was 85% for typical and 57% for atypical carcinoids., Conclusion: Carcinoid tumors are malignant tumors by their ability to metastasize. In our study, both histological type and staging were predictors of survival., (Copyright © 2012 Elsevier España, S.L. All rights reserved.)
Published: 2013
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