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1. Which inflammatory marker, between systemic immune-inflammation index and neutrophil to eosinophil ratio, is associated with Peyronie’s disease and are there any implications for a better understanding of its mechanisms?

Author

Crocetto, Felice, Imbimbo, Ciro, Barone, Biagio, Turchino, Davide, Bracale, Umberto Marcello, Peluso, Antonio, Panagrosso, Marco, Falcone, Alfonso, Mirto, Benito Fabio, De Luca, Luigi, Sicignano, Enrico, Del Giudice, Francesco, Busetto, Gian Maria, Lucarelli, Giuseppe, Giampaglia, Gaetano, Manfredi, Celeste, Ferro, Matteo, and Tarantino, Giovanni

Published
2023
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3. Current Applications and Future Perspectives of Artificial and Biomimetic Intelligence in Vascular Surgery and Peripheral Artery Disease.

Author

Martelli, Eugenio, Capoccia, Laura, Di Francesco, Marco, Cavallo, Eduardo, Pezzulla, Maria Giulia, Giudice, Giorgio, Bauleo, Antonio, Coppola, Giuseppe, and Panagrosso, Marco

Subjects
ARTIFICIAL neural networks, ARTIFICIAL intelligence, PERIPHERAL vascular diseases, CONVOLUTIONAL neural networks, VASCULAR surgery
Abstract

Artificial Intelligence (AI) made its first appearance in 1956, and since then it has progressively introduced itself in healthcare systems and patients' information and care. AI functions can be grouped under the following headings: Machine Learning (ML), Deep Learning (DL), Artificial Neural Network (ANN), Convolutional Neural Network (CNN), Computer Vision (CV). Biomimetic intelligence (BI) applies the principles of systems of nature to create biological algorithms, such as genetic and neural network, to be used in different scenarios. Chronic limb-threatening ischemia (CLTI) represents the last stage of peripheral artery disease (PAD) and has increased over recent years, together with the rise in prevalence of diabetes and population ageing. Nowadays, AI and BI grant the possibility of developing new diagnostic and treatment solutions in the vascular field, given the possibility of accessing clinical, biological, and imaging data. By assessing the vascular anatomy in every patient, as well as the burden of atherosclerosis, and classifying the level and degree of disease, sizing and planning the best endovascular treatment, defining the perioperative complications risk, integrating experiences and resources between different specialties, identifying latent PAD, thus offering evidence-based solutions and guiding surgeons in the choice of the best surgical technique, AI and BI challenge the role of the physician's experience in PAD treatment. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Sex Related Differences and Factors Associated With Peri-Procedural and One Year Mortality in Chronic Limb Threatening Ischaemia Patients

Author

Martelli, Eugenio, Zamboni, Matilde, Sotgiu, Giovanni, Saderi, Laura, Federici, Massimo, Sangiorgi, Giuseppe, Puci, Mariangela Valentina, Martelli, Allegra Rosa, Messina, Teresa, Frigatti, Paolo, Borrelli, Maria Pia, Ruotolo, Carlo, Ficarelli, Ilaria, Rubino, Paolo, Pezzo, Francesco, Carbonari, Luciano, Angelini, Andrea, Galeazzi, Edoardo, Calia di Pinto, Luca, Fiore, Franco Michelino, Palmieri, Armando, Ventoruzzo, Giorgio, Mazzitelli, Giulia, Ragni, Franco, Bozzani, Antonio, Forliti, Enzo, Castagno, Claudio, Volpe, Pietro, Massaro, Mafalda, Moniaci, Diego, Pagliasso, Elisa, Peretti, Tania, Ferrari, Mauro, Troisi, Nicola, Modugno, Piero, Maiorano, Maurizio, Bracale, Umberto Marcello, Panagrosso, Marco, Monaco, Mario, Giordano, Giovanni, Natalicchio, Giuseppe, Biello, Antonella, Celoria, Giovanni Maria, Amico, Alessio, Di Bartolo, Mauro, Martelli, Massimiliano, Munaò, Roberta, Razzano, Davide, Colacchio, Giovanni, Bussetti, Francesco, Lanza, Gaetano, Cardini, Antonio, Di Benedetto, Bartolomeo, De Laurentis, Mario, Taurino, Maurizio, Sirignano, Pasqualino, Cappiello, Pierluigi, Esposito, Andrea, Trimarchi, Santi, Romagnoli, Silvia, Padricelli, Andrea, Giudice, Giorgio, Crinisio, Adolfo, Di Nardo, Giovanni, Battaglia, Giuseppe, Tringale, Rosario, De Vivo, Salvatore, Compagna, Rita, Tolva, Valerio Stefano, D'Alessio, Ilenia, Curci, Ruggiero, Giovannetti, Simona, D'Arrigo, Giuseppe, Basile, Giusi, Frigerio, Dalmazio, Veraldi, Gianfranco, Mezzetto, Luca, Ippoliti, Arnaldo, Oddi, Fabio Massimo, and Settembrini, Alberto Maria

Published
2024
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6. Sex-Related Differences and Factors Associated with Peri-Procedural and 1 Year Mortality in Chronic Limb-Threatening Ischemia Patients from the CLIMATE Italian Registry

Author

Martelli, Eugenio, primary, Zamboni, Matilde, additional, Sotgiu, Giovanni, additional, Saderi, Laura, additional, Federici, Massimo, additional, Sangiorgi, Giuseppe M., additional, Puci, Mariangela V., additional, Martelli, Allegra R., additional, Messina, Teresa, additional, Frigatti, Paolo, additional, Borrelli, Maria Pia, additional, Ruotolo, Carlo, additional, Ficarelli, Ilaria, additional, Rubino, Paolo, additional, Pezzo, Francesco, additional, Carbonari, Luciano, additional, Angelini, Andrea, additional, Galeazzi, Edoardo, additional, Di Pinto, Luca Calia, additional, Fiore, Franco M., additional, Palmieri, Armando, additional, Ventoruzzo, Giorgio, additional, Mazzitelli, Giulia, additional, Ragni, Franco, additional, Bozzani, Antonio, additional, Forliti, Enzo, additional, Castagno, Claudio, additional, Volpe, Pietro, additional, Massara, Mafalda, additional, Moniaci, Diego, additional, Pagliasso, Elisa, additional, Peretti, Tania, additional, Ferrari, Mauro, additional, Troisi, Nicola, additional, Modugno, Piero, additional, Maiorano, Maurizio, additional, Bracale, Umberto M., additional, Panagrosso, Marco, additional, Monaco, Mario, additional, Giordano, Giovanni, additional, Natalicchio, Giuseppe, additional, Biello, Antonella, additional, Celoria, Giovanni M., additional, Amico, Alessio, additional, Di Bartolo, Mauro, additional, Martelli, Massimiliano, additional, Munaó, Roberta, additional, Razzano, Davide, additional, Colacchio, Giovanni, additional, Bussetti, Francesco, additional, Lanza, Gaetano, additional, Cardini, Antonio, additional, Di Benedetto, Bartolomeo, additional, De Laurentis, Mario, additional, Taurino, Maurizio, additional, Sirignano, Pasqualino, additional, Cappiello, Pierluigi, additional, Esposito, Andrea, additional, Trimarchi, Santi, additional, Romagnoli, Silvia, additional, Padricelli, Andrea, additional, Giudice, Giorgio, additional, Crinisio, Adolfo, additional, Di Nardo, Giovanni, additional, Battaglia, Giuseppe, additional, Tringale, Rosario, additional, De Vivo, Salvatore, additional, Compagna, Rita, additional, Tolva, Valerio S., additional, D’Alessio, Ilenia, additional, Curci, Ruggiero, additional, Giovannetti, Simona, additional, D’Arrigo, Giuseppe, additional, Basile, Giusi, additional, Frigerio, Dalmazio, additional, Veraldi, Gian Franco, additional, Mezzetto, Luca, additional, Ippoliti, Arnaldo, additional, Oddi, Fabio M., additional, and Settembrini, Alberto M., additional

Published
2023
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7. Sex-Related Differences and Factors Associated with Peri-Procedural and 1-year Mortality in Chronic Limb-Threatening Ischemia Patients from the CLIMATE Italian Registry

Author

Martelli, Eugenio, primary, Zamboni, Matilde, additional, Sotgiu, Giovanni, additional, Saderi, Laura, additional, Federici, Massimo, additional, Sangiorgi, Giuseppe Massimo, additional, Puci, Mariangela Valentina, additional, Martelli, Allegra Rosa, additional, Messina, Teresa, additional, Frigatti, Paolo, additional, Borrelli, Maria Pia, additional, Ruotolo, Carlo, additional, Ficarelli, Ilaria, additional, Rubino, Paolo, additional, Pezzo, Francesco, additional, Carbonari, Luciano, additional, Angelini, Andrea, additional, Galeazzi, Edoardo, additional, Di Pinto, Luca Calia, additional, Fiore, Franco Michelino, additional, Palmieri, Armado, additional, Ventoruzzo, Giorgio, additional, Mazzitelli, Giulia, additional, Ragni, Franco, additional, Bozzani, Antonio, additional, Forliti, Enzo, additional, Castagno, Claudio, additional, Volpe, Pietro, additional, Massara, Mafalda, additional, Moniaci, Diego, additional, Pagliasso, Elisa, additional, Peretti, Tania, additional, Ferrari, Mauro, additional, Troisi, Nicola, additional, Modugno, Pietro, additional, Maiorano, Maurizio, additional, Bracale, Umberto Marcello, additional, Panagrosso, Marco, additional, Monaco, Mario, additional, Giordano, Giovanni, additional, Natalicchio, Giuseppe, additional, Biello, Antonella, additional, Celoria, Giovanni Maria, additional, Amico, Alessio, additional, Di Bartolo, Mauro, additional, Martelli, Massimiliano, additional, Munaó, Roberta, additional, Razzano, Davide, additional, Colacchio, Giovanni, additional, Bussetti, Francesco, additional, Lanza, Gaetano, additional, Cardini, Antonio, additional, Di Benedetto, Bartolomeo, additional, De Laurentis, Mario, additional, Taurino, Maurizio, additional, Sirignano, Pasqualino, additional, Cappiello, Pierluigi, additional, Esposito, Andrea, additional, Trimarchi, Santi, additional, Romagnoli, Silvia, additional, Padricelli, Andrea, additional, Giudice, Giorgio, additional, Crinisio, Adolfo, additional, Di Nardo, Giovanni, additional, Battaglia, Giuseppe, additional, Tringale, Rosario, additional, De Vivo, Salvatore, additional, Compagna, Rita, additional, Tolva, Valerio Stefano, additional, D'Alessio, Ilenia, additional, Curci, Ruggiero, additional, Giovannetti, Simona, additional, D'Arrigo, Giuseppe, additional, Basile, Giusi, additional, Frigerio, Dalmazio, additional, Veraldi, Gian Franco, additional, Mezzetto, Luca, additional, Ippoliti, Arnaldo, additional, Oddi, Fabio Massimo, additional, and Settembrini, Alberto Maria, additional

Published
2022
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9. How the First Year of the COVID-19 Pandemic Impacted Patients’ Hospital Admission and Care in the Vascular Surgery Divisions of the Southern Regions of the Italian Peninsula

Author

Martelli, Eugenio, primary, Sotgiu, Giovanni, additional, Saderi, Laura, additional, Federici, Massimo, additional, Sangiorgi, Giuseppe, additional, Zamboni, Matilde, additional, Martelli, Allegra R., additional, Accarino, Giancarlo, additional, Bianco, Giuseppe, additional, Bonanno, Francesco, additional, Bracale, Umberto M., additional, Cappello, Enrico, additional, Cioffi, Giovanni, additional, Colacchio, Giovanni, additional, Crinisio, Adolfo, additional, De Vivo, Salvatore, additional, Dionisi, Carlo Patrizio, additional, Flora, Loris, additional, Impedovo, Giovanni, additional, Intrieri, Francesco, additional, Iorio, Luca, additional, Maritati, Gabriele, additional, Modugno, Piero, additional, Monaco, Mario, additional, Natalicchio, Giuseppe, additional, Palazzo, Vincenzo, additional, Petrosino, Fernando, additional, Pompeo, Francesco, additional, Pulli, Raffaele, additional, Razzano, Davide, additional, Ruggieri, Maurizio R., additional, Ruotolo, Carlo, additional, Sangiuolo, Paolo, additional, Vigliotti, Gennaro, additional, Volpe, Pietro, additional, Biello, Antonella, additional, Boggia, Pietro, additional, Boschetti, Michelangelo, additional, Centritto, Enrico M., additional, Condò, Flavia, additional, Cucciolillo, Lucia, additional, D’Amodio, Amodio S., additional, De Laurentis, Mario, additional, Desantis, Claudio, additional, Di Lella, Daniela, additional, Di Nardo, Giovanni, additional, Disabato, Angelo, additional, Ficarelli, Ilaria, additional, Gasparre, Angelo, additional, Giordano, Antonio N., additional, Luongo, Alessandro, additional, Massara, Mafalda, additional, Molinari, Vincenzo, additional, Padricelli, Andrea, additional, Panagrosso, Marco, additional, Petrone, Anna, additional, Pisanello, Serena, additional, Prunella, Roberto, additional, Tedesco, Michele, additional, and Settembrini, Alberto M., additional

Published
2022
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11. How the First Year of the COVID-19 Pandemic Impacted Patients’ Care in the Vascular Surgery Divisions of the Southern Regions of the Italian Peninsula

Author

Martelli, Eugenio, primary, Sotgiu, Giovanni, additional, Saderi, Laura, additional, Federici, Massimo, additional, Sangiorgi, Giuseppe, additional, Zamboni, Matilde, additional, Martelli, Allegra Rosa, additional, Accarino, Giancarlo, additional, Bianco, Giuseppe, additional, Bonanno, Francesco, additional, Bracale, Umberto Marcello, additional, Cappello, Enrico, additional, Cioffi, Giovanni, additional, Colacchio, Giovanni, additional, Crinisio, Adolfo, additional, De Vivo, Salvatore, additional, Dionisi, Carlo Patrizio, additional, Flora, Loris, additional, Impedovo, Giovanni, additional, Intrieri, Francesco, additional, Iorio, Luca, additional, Maritati, Gabriele, additional, Modugno, Piero, additional, Monaco, Mario, additional, Natalicchio, Giuseppe, additional, Palazzo, Vincenzo, additional, Petrosino, Fernando, additional, Pompeo, Francesco, additional, Pulli, Raffaele, additional, Razzano, Davide, additional, Ruggieri, Maurizio Ruggero, additional, Ruotolo, Carlo, additional, Sangiuolo, Paolo, additional, Vigliotti, Gennaro, additional, Volpe, Pietro, additional, Biello, Antonella, additional, Boggia, Pietro, additional, Boschetti, Michelangelo, additional, Centritto, Enrico Maria, additional, Condò, Flavia, additional, Cucciolillo, Lucia, additional, D'Amodio, Amodio Salvatore, additional, De Laurentis, Mario, additional, Desantis, Claudio, additional, Di Lella, Daniela, additional, Di Nardo, Giovanni, additional, Disabato, Angelo, additional, Ficarelli, Ilaria, additional, Gasparre, Angelo, additional, Giordano, Antonio Nicola, additional, Luongo, Alessandro, additional, Massara, Mafalda, additional, Molinari, Vincenzo, additional, Padricelli, Andrea, additional, Panagrosso, Marco, additional, Petrone, Anna, additional, Pisanello, Serena, additional, Prunella, Roberto, additional, Tedesco, Michele, additional, and Settembrini, Alberto Maria, additional

Published
2022
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14. Position Paper on Young Vascular Surgeons Training of the Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS): State of the Art and Perspectives

Author

Bracale, Umberto Marcello, Ammollo, Raffaele Pio, Hussein, Emad A., Hoballah, Jamal J., Taurino, Maurizio, Saleem, Ben R., Setacci, Carlo, Pecoraro, Felice, Serra, Raffaele, Bracale, Giancarlo, Panagrosso, Marco, Peluso, Antonio, Petrone, Anna, Maisto, Marianna, del Guercio, Luca, Dinoto, Ettore, Bajardi, Guido, Bouayed, Mohamed N., Zeebregts, Clark J., Pulli, Raffaele, Pane, Bianca, Pratesi, Giovanni, Castelli, Patrizio, Setacci, Francesco, Gargiulo, Mauro, Stella, Andrea, Illario, Maddalena, De Luca, Vincenzo, Verhoeven, Eric L.G., Riambau, Vincent, Saratzis, Nikolaos, Cvjetko, Ivan, Resch, Timothy, Fernandes e Fernandes, José, Chiche, Laurent, and Goeau-Brissonniere, Olivier

Published
2021
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17. Collagen-Based Vascular Closure Device Multicenter Italian Experience in Endovascular Aortic Aneurysm Repair Compared With Suture-Mediated Closure Vascular Device

Author

Panagrosso, Marco, Cavallo, Eduardo, Bracale, Umberto Marcello, Peluso, Antonio, Silvestri, Olga, Intrieri, Francesco, Molinari, Vincenzo, Esposito, Antonio, Trimarchi, Santi, Settembrini, Alberto Maria, Lomazzi, Chiara, La Barbera, Gaetano, Carbonari, Luciano, Angelini, Andrea, Morelli, Irene, Centonza, Eleonora, Berchiolli, Raffaella, Troisi, Nicola, Scarati, Valentina, Artini, Valerio, De Vivo, Salvatore, Volpe, Pietro, Massara, Mafalda, and Martelli, Eugenio

Abstract

Purpose: The Manta Vascular Closure Device is a novel collagen-based vascular closure device that has been designed specifically for closure of large-bore percutaneous arterial accesses. The aim of this retrospective study is to evaluate the immediate and 30-day outcome of Manta at the completion of endovascular aneurysm repair (EVAR) or thoracic endovascular aortic repair (TEVAR). The hypothesis is that Manta is not inferior in obtaining hemostasis compared with the Perclose ProGlide Suture-Mediated Closure System device.Materials and Methods: We recruited all the percutaneous accesses for (T)EVAR performed from January 2021 to April 2023 by all the Italian Divisions of Vascular Surgery using Manta at the time of data collection (May 2023). The primary outcome is to evaluate the incidence of complications at the puncture site after Manta implantation and at 1 month, and compare this with ProGlide. We applied the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) criteria for observational studies.Results: Overall, 524 consecutive femoral accesses for (T)EVAR procedures were collected: 355 in the Manta cohort and 169 in the ProGlide cohort, respectively. The size of the sheath was 17.2±2.7 Fr for Manta, 15.7±2.3 Fr for ProGlide (p<0.001). No statistically significant differences between the groups regarding age, sex, body mass index, ultrasound-guided access, femoral calcifications, intraoperative, and 30-day complications. Successful arterial closure at groin puncture sites for (T)EVAR using Manta is 90.5% and 93.1% using ProGlide. Freedom for any reintervention for any complication is 95.5% for Manta and 96% for ProGlide.Conclusion: The 2 vascular closure devices have proved to be similar in terms of complications, without any statistically significant difference, although the median size of the sheaths for (T)EVAR was statistically significantly larger when Manta has been used, compared with ProGlide.Clinical Impact Manta® is effective in the hemostasis of the access sites following the completion of (T)EVAR in this multicenter, retrospective, case-control study on 524 percutaneous femoral accesses. Compared to the more popular Proglide®, the average size of the introducers in the Manta® group was significantly larger than in the Proglide® group.

Published
2024
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18. Sequential Minimally Invasive Treatment of Concomitant Abdominal Aortic Aneurysm and Colorectal Cancer: A Single-Center Experience

Author

Bracale, Umberto, Di Nuzzo, Maria Michela, Bracale, Umberto Marcello, Del Guercio, Luca, Panagrosso, Marco, Serra, Raffaele, Terracciano, Rosa Maria, De Werra, Carlo, Corcione, Francesco, Peltrini, Roberto, and Sodo, Maurizio

Abstract

The surgical management of concomitant occurrence of abdominal aortic aneurysm (AAA) and colorectal cancer (CRC) is still controversial. Conversely, benefits from a minimally invasive approach are well known concerning the treatment of both AAA and CRC. The aim of this study is to assess safety and feasibility of a sequential 2-staged minimally invasive during the same recovery by endovascular aneurysm repair (EVAR) technique and laparoscopic colorectal resection.

Published
2021
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19. Sex-Related Differences and Factors Associated with Peri-Procedural and 1 Year Mortality in Chronic Limb-Threatening Ischemia Patients from the CLIMATE Italian Registry

Author

Eugenio Martelli, Matilde Zamboni, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe M. Sangiorgi, Mariangela V. Puci, Allegra R. Martelli, Teresa Messina, Paolo Frigatti, Maria Pia Borrelli, Carlo Ruotolo, Ilaria Ficarelli, Paolo Rubino, Francesco Pezzo, Luciano Carbonari, Andrea Angelini, Edoardo Galeazzi, Luca Calia Di Pinto, Franco M. Fiore, Armando Palmieri, Giorgio Ventoruzzo, Giulia Mazzitelli, Franco Ragni, Antonio Bozzani, Enzo Forliti, Claudio Castagno, Pietro Volpe, Mafalda Massara, Diego Moniaci, Elisa Pagliasso, Tania Peretti, Mauro Ferrari, Nicola Troisi, Piero Modugno, Maurizio Maiorano, Umberto M. Bracale, Marco Panagrosso, Mario Monaco, Giovanni Giordano, Giuseppe Natalicchio, Antonella Biello, Giovanni M. Celoria, Alessio Amico, Mauro Di Bartolo, Massimiliano Martelli, Roberta Munaó, Davide Razzano, Giovanni Colacchio, Francesco Bussetti, Gaetano Lanza, Antonio Cardini, Bartolomeo Di Benedetto, Mario De Laurentis, Maurizio Taurino, Pasqualino Sirignano, Pierluigi Cappiello, Andrea Esposito, Santi Trimarchi, Silvia Romagnoli, Andrea Padricelli, Giorgio Giudice, Adolfo Crinisio, Giovanni Di Nardo, Giuseppe Battaglia, Rosario Tringale, Salvatore De Vivo, Rita Compagna, Valerio S. Tolva, Ilenia D’Alessio, Ruggiero Curci, Simona Giovannetti, Giuseppe D’Arrigo, Giusi Basile, Dalmazio Frigerio, Gian Franco Veraldi, Luca Mezzetto, Arnaldo Ippoliti, Fabio M. Oddi, Alberto M. Settembrini, Martelli, Eugenio, Zamboni, Matilde, Sotgiu, Giovanni, Saderi, Laura, Federici, Massimo, Sangiorgi, Giuseppe M., Puci, Mariangela V., Martelli, Allegra R., Messina, Teresa, Frigatti, Paolo, Borrelli, Maria Pia, Ruotolo, Carlo, Ficarelli, Ilaria, Rubino, Paolo, Pezzo, Francesco, Carbonari, Luciano, Angelini, Andrea, Galeazzi, Edoardo, Di Pinto, Luca Calia Di, Fiore, Franco M., Palmieri, Armando, Ventoruzzo, Giorgio, Mazzitelli, Giulia, Ragni, Franco, Bozzani, Antonio, Forliti, Enzo, Castagno, Claudio, Volpe, Pietro, Massara, Mafalda, Moniaci, Diego, Pagliasso, Elisa, Peretti, Tania, Ferrari, Mauro, Troisi, Nicola, Modugno, Piero, Maiorano, Maurizio, Bracale, Umberto M., Panagrosso, Marco, Monaco, Mario, Giordano, Giovanni, Natalicchio, Giuseppe, Biello, Antonella, Celoria, Giovanni M., Amico, Alessio, Di Bartolo, Mauro, Martelli, Massimiliano, Munaó, Roberta, Razzano, Davide, Colacchio, Giovanni, Bussetti, Francesco, Lanza, Gaetano, Cardini, Antonio, Di Benedetto, Bartolomeo, De Laurentis, Mario, Taurino, Maurizio, Sirignano, Pasqualino, Cappiello, Pierluigi, Esposito, Andrea, Trimarchi, Santi, Romagnoli, Silvia, Padricelli, Andrea, Giudice, Giorgio, Crinisio, Adolfo, Di Nardo, Giovanni, Battaglia, Giuseppe, Tringale, Rosario, De Vivo, Salvatore, Compagna, Rita, Tolva, Valerio S., D’Alessio, Ilenia, Curci, Ruggiero, Giovannetti, Simona, D’Arrigo, Giuseppe, Basile, Giusi, Frigerio, Dalmazio, Veraldi, Gian Franco, Mezzetto, Luca, Ippoliti, Arnaldo, Oddi, Fabio M., and Settembrini, Alberto M.

Subjects
chronic limb-threatening ischemia, age, limb salvage, outcome, sex, Medicine (miscellaneous), Settore MED/09
Abstract

Background: Identifying sex-related differences/variables associated with 30 day/1 year mortality in patients with chronic limb-threatening ischemia (CLTI). Methods: Multicenter/retrospective/observational study. A database was sent to all the Italian vascular surgeries to collect all the patients operated on for CLTI in 2019. Acute lower-limb ischemia and neuropathic-diabetic foot are not included. Follow-up: One year. Data on demographics/comorbidities, treatments/outcomes, and 30 day/1 year mortality were investigated. Results: Information on 2399 cases (69.8% men) from 36/143 (25.2%) centers. Median (IQR) age: 73 (66–80) and 79 (71–85) years for men/women, respectively (p < 0.0001). Women were more likely to be over 75 (63.2% vs. 40.1%, p = 0.0001). More men smokers (73.7% vs. 42.2%, p < 0.0001), are on hemodialysis (10.1% vs. 6.7%, p = 0.006), affected by diabetes (61.9% vs. 52.8%, p < 0.0001), dyslipidemia (69.3% vs. 61.3%, p < 0.0001), hypertension (91.8% vs. 88.5%, p = 0.011), coronaropathy (43.9% vs. 29.4%, p < 0.0001), bronchopneumopathy (37.1% vs. 25.6%, p < 0.0001), underwent more open/hybrid surgeries (37.9% vs. 28.8%, p < 0.0001), and minor amputations (22% vs. 13.7%, p < 0.0001). More women underwent endovascular revascularizations (61.6% vs. 55.2%, p = 0.004), major amputations (9.6% vs. 6.9%, p = 0.024), and obtained limb-salvage if with limited gangrene (50.8% vs. 44.9%, p = 0.017). Age > 75 (HR = 3.63, p = 0.003) is associated with 30 day mortality. Age > 75 (HR = 2.14, p < 0.0001), nephropathy (HR = 1.54, p < 0.0001), coronaropathy (HR = 1.26, p = 0.036), and infection/necrosis of the foot (dry, HR = 1.42, p = 0.040; wet, HR = 2.04, p < 0.0001) are associated with 1 year mortality. No sex-linked difference in mortality statistics. Conclusion: Women exhibit fewer comorbidities but are struck by CLTI when over 75, a factor associated with short- and mid-term mortality, explaining why mortality does not statistically differ between the sexes.

Published
2023

20. Sequential Minimally Invasive Treatment of Concomitant Abdominal Aortic Aneurysm and Colorectal Cancer: A Single-Center Experience

Author

Carlo De Werra, Umberto Bracale, Maria Michela Di Nuzzo, Luca del Guercio, Raffaele Serra, Maurizio Sodo, Rosa Maria Terracciano, Marco Panagrosso, Roberto Peltrini, Francesco Corcione, Bracale, Umberto, Di Nuzzo, Maria Michela, Bracale, Umberto Marcello, Del Guercio, Luca, Panagrosso, Marco, Serra, Raffaele, Terracciano, Rosa Maria, De Werra, Carlo, Corcione, Francesco, Peltrini, Roberto, and Sodo, Maurizio

Subjects
Male, Laparoscopic surgery, medicine.medical_specialty, Time Factors, Percutaneous, medicine.medical_treatment, Endovascular aneurysm repair, Blood Vessel Prosthesis Implantation, Postoperative Complications, Aneurysm, medicine.artery, medicine, Humans, Colectomy, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Abdominal aortic aneurysm, Endovascular aneurysm repair, Colorectal cancer, Laparoscopic surgery, Endovascular Procedures, General Medicine, Perioperative, Length of Stay, medicine.disease, Common iliac artery, Abdominal aortic aneurysm, Surgery, Treatment Outcome, Concomitant, Female, Laparoscopy, Colorectal Neoplasms, Cardiology and Cardiovascular Medicine, business, Aortic Aneurysm, Abdominal
Abstract

Background The surgical management of concomitant occurrence of abdominal aortic aneurysm (AAA) and colorectal cancer (CRC) is still controversial. Conversely, benefits from a minimally invasive approach are well known concerning the treatment of both AAA and CRC. The aim of this study is to assess safety and feasibility of a sequential 2-staged minimally invasive during the same recovery by endovascular aneurysm repair (EVAR) technique and laparoscopic colorectal resection. Methods From January 2008 to December 2020, all patients with concomitant AAA and CRC were consecutively treated by EVAR and laparoscopic colorectal resection. Perioperative data were retrospectively collected in order to evaluate short- and long-term outcomes following the sequential 2-staged procedures. Results A total of 24 patients were included. The localization of the aneurysm was infrarenal abdominal aortic in 23 cases and in one case of common iliac artery. EVAR procedure has always been performed first. In 18 patients, a percutaneous access has been used while in 6 patients a surgical access has been adopted. Twelve patients had cancer in the left colon, 9 in the right colon, and 3 patients had rectal cancer. No conversions or intraoperative complications had occurred during laparoscopic surgery. The major complications rate after EVAR and CRC surgery was 8.3% and 12.5%, respectively. The mean interval between EVAR and CRC treatment was 7.8 ± 1 and the mean length of stay was 15.4 ± 3.6. No deaths occurred during hospitalization and between the procedures. Overall mortality was 20.8% with a mean follow-up of 39.41 ± 19.2 months. Conclusion Elective sequential 2-staged minimally invasive treatment is a safe and feasible approach with acceptable morbidity and mortality rates and it should be adopted in current clinical practice to manage concomitant AAA and CRC.

Published
2022

21. How the First Year of the COVID-19 Pandemic Impacted Patients' Hospital Admission and Care in the Vascular Surgery Divisions of the Southern Regions of the Italian Peninsula

Author

Eugenio Martelli, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe Sangiorgi, Matilde Zamboni, Allegra R. Martelli, Giancarlo Accarino, Giuseppe Bianco, Francesco Bonanno, Umberto M. Bracale, Enrico Cappello, Giovanni Cioffi, Giovanni Colacchio, Adolfo Crinisio, Salvatore De Vivo, Carlo Patrizio Dionisi, Loris Flora, Giovanni Impedovo, Francesco Intrieri, Luca Iorio, Gabriele Maritati, Piero Modugno, Mario Monaco, Giuseppe Natalicchio, Vincenzo Palazzo, Fernando Petrosino, Francesco Pompeo, Raffaele Pulli, Davide Razzano, Maurizio R. Ruggieri, Carlo Ruotolo, Paolo Sangiuolo, Gennaro Vigliotti, Pietro Volpe, Antonella Biello, Pietro Boggia, Michelangelo Boschetti, Enrico M. Centritto, Flavia Condò, Lucia Cucciolillo, Amodio S. D’Amodio, Mario De Laurentis, Claudio Desantis, Daniela Di Lella, Giovanni Di Nardo, Angelo Disabato, Ilaria Ficarelli, Angelo Gasparre, Antonio N. Giordano, Alessandro Luongo, Mafalda Massara, Vincenzo Molinari, Andrea Padricelli, Marco Panagrosso, Anna Petrone, Serena Pisanello, Roberto Prunella, Michele Tedesco, Alberto M. Settembrini, Martelli, Eugenio, Sotgiu, Giovanni, Saderi, Laura, Federici, Massimo, Sangiorgi, Giuseppe, Zamboni, Matilde, Martelli, Allegra R., Accarino, Giancarlo, Bianco, Giuseppe, Bonanno, Francesco, Bracale, Umberto M., Cappello, Enrico, Cioffi, Giovanni, Colacchio, Giovanni, Crinisio, Adolfo, De Vivo, Salvatore, Dionisi, Carlo Patrizio, Flora, Lori, Impedovo, Giovanni, Intrieri, Francesco, Iorio, Luca, Maritati, Gabriele, Modugno, Piero, Monaco, Mario, Natalicchio, Giuseppe, Palazzo, Vincenzo, Petrosino, Fernando, Pompeo, Francesco, Pulli, Raffaele, Razzano, Davide, Ruggieri, Maurizio R., Ruotolo, Carlo, Sangiuolo, Paolo, Vigliotti, Gennaro, Volpe, Pietro, Biello, Antonella, Boggia, Pietro, Boschetti, Michelangelo, Centritto, Enrico M., Condò, Flavia, Cucciolillo, Lucia, D’Amodio, Amodio S., De Laurentis, Mario, Desantis, Claudio, Di Lella, Daniela, Di Nardo, Giovanni, Disabato, Angelo, Ficarelli, Ilaria, Gasparre, Angelo, Giordano, Antonio N., Luongo, Alessandro, Massara, Mafalda, Molinari, Vincenzo, Padricelli, Andrea, Panagrosso, Marco, Petrone, Anna, Pisanello, Serena, Prunella, Roberto, Tedesco, Michele, and Settembrini, Alberto M.

Subjects
carotid stenosi, chronic limb-threatening ischemia, abdominal aortic aneurysm, amputation, Medicine (miscellaneous), COVID-19, carotid stenosis, deep venous thrombosis, Settore MED/09
Abstract

Background: To investigate the effects of the COVID-19 lockdowns on the vasculopathic population. Methods: The Divisions of Vascular Surgery of the southern Italian peninsula joined this multicenter retrospective study. Each received a 13-point questionnaire investigating the hospitalization rate of vascular patients in the first 11 months of the COVID-19 pandemic and in the preceding 11 months. Results: 27 out of 29 Centers were enrolled. April-December 2020 (7092 patients) vs. 2019 (9161 patients): post-EVAR surveillance, hospitalization for Rutherford category 3 peripheral arterial disease, and asymptomatic carotid stenosis revascularization significantly decreased (1484 (16.2%) vs. 1014 (14.3%), p = 0.0009; 1401 (15.29%) vs. 959 (13.52%), p = 0.0006; and 1558 (17.01%) vs. 934 (13.17%), p < 0.0001, respectively), while admissions for revascularization or major amputations for chronic limb-threatening ischemia and urgent revascularization for symptomatic carotid stenosis significantly increased (1204 (16.98%) vs. 1245 (13.59%), p < 0.0001; 355 (5.01%) vs. 358 (3.91%), p = 0.0007; and 153 (2.16%) vs. 140 (1.53%), p = 0.0009, respectively). Conclusions: The suspension of elective procedures during the COVID-19 pandemic caused a significant reduction in post-EVAR surveillance, and in the hospitalization of asymptomatic carotid stenosis revascularization and Rutherford 3 peripheral arterial disease. Consequentially, we observed a significant increase in admissions for urgent revascularization for symptomatic carotid stenosis, as well as for revascularization or major amputations for chronic limb-threatening ischemia.

Published
2022

22. Ankle-Brachial Index evaluation in totally percutaneous approach vs. femoral artery cutdown for endovascular aortic repair of abdominal aortic aneurysms

Author

Umberto M. BRACALE, Antonio PELUSO, Marco PANAGROSSO, Fabrizio CECERE, Luca DEL GUERCIO, Roberto MINICI, Nicola GIANNOTTA, Nicola IELAPI, Noemi LICASTRO, Giuseppe F. SERRAINO, Pasquale MASTROROBERTO, Michele ANDREUCCI, Raffaele SERRA, Bracale, Umberto M., Peluso, Antonio, Panagrosso, Marco, Cecere, Fabrizio, DEL GUERCIO, Luca, Minici, Roberto, Giannotta, Nicola, Ielapi, Nicola, Licastro, Noemi, Serraino, Giuseppe F., Mastroroberto, Pasquale, Andreucci, Michele, and Serra, Raffaele

Subjects
abdominal, ankle-brachial index, aortic aneurysm, complications, femoral artery, Aortic aneurysm, abdominal, Surgery, Complication
Abstract

BACKGROUND: Endovascular abdominal aortic aneurysm repair (EVAR) should be considered as the preferred treatment modality for infrarenal abdominal aortic aneurysm for patients with suitable anatomy and reasonable life expectancy. Surgical cut-down of both femoral arteries during EVAR procedure is associated with an increased risk of local complications. Therefore, nowadays most EVAR procedures are performed with a totally percutaneous approach. METHODS: Based on the evaluation of the Ankle Brachial Index (ABI) variation, the purpose of this study was to evaluate possible hemodynamic alterations on arterial perfusion of the lower limbs in two different types of access for EVAR procedures: totally percutaneous (p-EVAR) and EVAR with surgical access (s-EVAR). RESULTS: Our study considered 38 patients (36 men, mean age of 70.6±8.3 years) subjected to EVAR procedure between January 1, 2019 and December 31, 2020. The variation in pre- and postoperative ABI values (∆ ABI) and procedure-related complications rate were considered as primary outcomes. The p-EVAR group consisted of 27 patients (92.6% males, mean age of 72.3±8.6) while the s-EVAR group was composed by 11 patients (100% males, mean age of 69±8.1). The follow-up period was ranged from a minimum of 6 to a maximum of 12.3 months. In particular, the pre- and postoperative Δ ABI and the procedure-related complications rate, both considered as primary outcomes, did not show any significant difference between two groups, and in both groups, the technical success rate was 100%. CONCLUSIONS: Pre- and postoperative Δ ABI and the procedure-related complications rate, did not show any significant difference between two groups. We can confirm that percutaneous access is safe, and its use should be encouraged when any contraindication on his employment does not exist.

Published
2022

23. Single staged hybrid approach for multilevel aortic-iliac-femoral-popliteal disease

Author

Guido Bajardi, Umberto Bracale, Felice Pecoraro, Ettore Dinoto, Marco Panagrosso, Andrea Cutrupi, Dinoto, Ettore, Pecoraro, Felice, Cutrupi, Andrea, Bracale, Umberto M., Panagrosso, Marco, Bajardi, Guido, Dinoto E., Pecoraro F., Cutrupi A., Bracale U.M., Panagrosso M., and Bajardi G.

Subjects
medicine.medical_specialty, Arterial disease, medicine.medical_treatment, Disease, Revascularization, Renal artery stenosis, Settore MED/22 - Chirurgia Vascolare, 03 medical and health sciences, 0302 clinical medicine, Intensive care, medicine.artery, Case report, Peripheral arterial disease, medicine, Renal artery, Endovascular, business.industry, Blood flow, Hybrid approach, medicine.disease, Surgery, Hybrid procedure, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, business
Abstract

Highlights • Multilevel peripheral arterial disease in diabetic patients is cause of amputation. • Herein we report a case of critic limb ischemia addressed by hybrid procedure. • Hybrid procedure outcomes seem to be as good as with open revascularization. • Hybrid procedure show less morbidity and shorter intensive care and hospital stay., Introduction Multilevel peripheral arterial disease (MPAD) is the main cause of critic limb ischemia (CLI). Vascular interventions are required to increase distal blood flow and reduce the risk of lower limb amputation. Presentation of case We report a case of complex hybrid revascularization in a patient presenting a Rutherford V MPAD involving the infrarenal aorta, iliac, femoral and popliteal segments. The simultaneous hybrid intervention consisted of an endovascular aortic stent-graft placement and a surgical above-the-knee prosthetic femoro-popliteal bypass. In the same operation a renal stenting was performed due to a significant renal artery stenosis associated to a systemic hypertension non-responder to medical management. Discussion Hybrid interventions can be performed simultaneously or staged with benefit given by the complementary role of endovascular and surgical treatments allowing the correction of eventually inadequate results of both approaches. Reports of simultaneous hybrid treatments are limited but, despite the complexity of such procedures, primary success rate is reported high. Also in the reported case, a complex simultaneous treatment in a patient presenting MPAD in association to a significant and symptomatic renal artery disease was feasible in the same operation. Conclusion Hybrid procedure are safe with high degree of efficacy in terms of revascularization procedure, reduced morbidity and shorter intensive care and hospital stay. In our experience, the use of hybrid procedure is technically feasible and allowed the treatment of MPAD with a good outcomes.

Published
2020

24. Position Paper on Young Vascular Surgeons Training of the Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS): State of the Art and Perspectives

Author

Carlo Setacci, Umberto Bracale, Mohamed N. Bouayed, Raffaele Serra, Antonio Peluso, Guido Bajardi, Vincenzo De Luca, Timothy Resch, Anna Petrone, Maurizio Taurino, Laurent Chiche, Eric L.G. Verhoeven, Mauro Gargiulo, Patrizio Castelli, Nikolaos Saratzis, Felice Pecoraro, Raffaele Pio Ammollo, Marianna Maisto, Marco Panagrosso, Giovanni Pratesi, Ben R. Saleem, Andrea Stella, Raffaele Pulli, Bianca Pane, Ivan Cvjetko, Clark J. Zeebregts, Maddalena Illario, Emad Hussein, Giancarlo Bracale, Olivier Goëau-Brissonnière, Luca del Guercio, José Fernandes e Fernandes, Ettore Dinoto, Vincent Riambau, Francesco Setacci, Jamal J. Hoballah, Man, Biomaterials and Microbes (MBM), Bracale, Umberto Marcello, Ammollo, Raffaele Pio, Hussein, Emad A, Hoballah, Jamal J, Taurino, Maurizio, Saleem, Ben R, Setacci, Carlo, Pecoraro, Felice, Serra, Raffaele, Bracale, Giancarlo, Panagrosso, Marco, Peluso, Antonio, Petrone, Anna, Maisto, Marianna, Guercio, Luca Del, Dinoto, Ettore, Bajardi, Guido, Bouayed, Mohamed N, Zeebregts, Clark J, Pulli, Raffaele, Pane, Bianca, Pratesi, Giovanni, Castelli, Patrizio, Setacci, Francesco, Gargiulo, Mauro, Stella, Andrea, Illario, Maddalena, De Luca, Vincenzo, Verhoeven, Eric L G, Riambau, Vincent, Saratzis, Nikolao, Cvjetko, Ivan, Resch, Timothy, Fernandes, José Fernandes E, Chiche, Laurent, and Goeau-Brissonniere, Olivier

Subjects
medicine.medical_specialty, Arterial disease, media_common.quotation_subject, Vascular Surgery, Settore MED/22 - Chirurgia Vascolare, Training (civil), Peripheral Arterial Disease, State (polity), medicine, Mediterranean Sea, Humans, Training, Economic impact analysis, Vascular surgery specialty, media_common, National health, Surgeons, business.industry, Mediterranean Region, Internship and Residency, General Medicine, Vascular surgery, endovascular surgery, Mediterranean sea, training, vascular surgery, Education, Medical, Graduate, Family medicine, Endovascular Surgery, Position paper, Surgery, Clinical Competence, Curriculum, Cardiology and Cardiovascular Medicine, business, Vascular Surgical Procedures, Diabetic Angiopathies, Learning Curve, Program Evaluation, Specialization
Abstract

The Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS) was founded in 2018, with the aim to promote cooperation among vascular professionals within Mediterranean countries. Due to its prominent social and economic impact on national health systems, diabetic peripheral artery was selected as the very first topic to be investigated by the federation. In this second paper, different experiences from delegates of participating countries were shared to define common strategies to harmonize, standardize, and optimize education and training in the Vascular Surgery specialty.

Published
2021

25. A case of large renal aneurysm treated with a combined endovascular-laparoscopic approach

Author

Davide Turchino, Giuseppe Boccia, Marco Panagrosso, Umberto Bracale, Maurizio Sodo, Raffaele Serra, Francesco Corcione, Umberto Marcello Bracale, Turchino, Davide, Boccia, Giuseppe, Panagrosso, Marco, Bracale, Umberto, Sodo, Maurizio, Serra, Raffaele, Corcione, Francesco, and Bracale, Umberto Marcello

Subjects
Renal artery aneurysm, Laparoscopy, Nephrectomy, Amplatzer vascular plug
Abstract

A 67-year-old man with pain in his right flank and hematuria over the last few weeks was admitted to our hospital due to right renal calculi revealed by an ultrasound examination of the urinary tract. An abdominal x-ray drew attention to the presence of structures of an uncertain interpretation, that mimicked multiple calculi in the right kidney and renal pelvis, but CT-scan identified a large saccular aneurysm of 76 mm with renal pelvis involvement and urinary statis of the right renal artery. A combined endovascular and laparoscopic surgical approach was chosen. The patient underwent endovascular embolization of the renal artery with an Amplatzer Vascular Plug followed by a video laparoscopic nephrectomy. After few days of hospitalization, the patient was in good general status and was discharged. A review of the literature has highlighted the unicity of our surgical approach, especially within the context of traditional vascular and general surgical practice, due to multidisciplinary consultation.

Published
2022

26. Endovascular treatment of extracranial carotid artery aneurysms with flow diverter stents

Author

Marco Panagrosso, Margherita Tarantino, Luca del Guercio, Giuseppe Buono, Raffaele Serra, Umberto Marcello Bracale, Francesco Briganti, Panagrosso, Marco, Tarantino, Margherita, del Guercio, Luca, Buono, Giuseppe, Serra, Raffaele, Bracale, Umberto Marcello, and Briganti, Francesco

Subjects
extracranialcarotid arteryaneurysmsflow diverter stents
Abstract

Extracranial carotid artery aneurysms (ECAAs) are not a common occurrence. As a result, its natural clinical course and the risk factors associated with an adverse outcome are largely unknown. Herein, we describe the endovascular treatment of two extracranial carotid artery aneurysms with flow diverter stents. Flow-diverter devices are stents placed in the parent artery at the level of the neck aneurysm in order to disrupt the intra-aneurysmal flow, thereby favoring intra-aneurysmal thrombosis. In the first case, an angio-CT scan was performed at one-month follow-up and in the second case a duplex scan was performed after four months. Both cases resulted in good stent positioning with complete exclusion of the aneurysm and complete carotid artery patency. Based upon our own clinical experience, endovascular treatment with flow diverter stents merit to be recognized and considered an option in cases of ECAA acknowledging that larger studies or larger series are needed to concur experience.

Published
2022

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