23 results on '"Palumbo, Michele"'
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2. Logistica e Supply Chain per non addetti ai lavori
- Author
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Palumbo, Michele, Belvedere, Valeria, Di Pietro, M., Palumbo M., Belvedere V. (ORCID:0000-0002-7748-5152), Palumbo, Michele, Belvedere, Valeria, Di Pietro, M., Palumbo M., and Belvedere V. (ORCID:0000-0002-7748-5152)
- Abstract
Il testo si propone come manuale utile a studenti e manager per le tematiche relative alla gestione della logistica, delle operations e della supply
- Published
- 2024
3. A real‐life study of daratumumab combinations in newly diagnosed patients with light chain (AL) amyloidosis.
- Author
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Bellofiore, Claudia, Benvenuti, Pietro, Mina, Roberto, Basset, Marco, Foli, Andrea, Nanci, Martina, Nuvolone, Mario, Guida, Gianluigi, Attanasio, Andrea, Mussinelli, Roberta, Mangiacavalli, Silvia, Cartia, Claudio Salvatore, Masoni, Valeria, Palumbo, Michele, Cani, Lorenzo, Oliva, Stefania, Consoli, Ugo, Conticello, Concetta, Di Raimondo, Francesco, and Arcaini, Luca
- Subjects
DARATUMUMAB ,AMYLOIDOSIS ,LENALIDOMIDE ,MULTIPLE myeloma ,BORTEZOMIB - Abstract
Daratumumab‐based regimens are the new standard of care for newly diagnosed patients with AL amyloidosis based on the results of the ANDROMEDA study. However, real‐world data on daratumumab efficacy in upfront therapy in unselected patients are scanty. In the framework of a prospective observational study, we investigated the efficacy and safety of daratumumab in 88 newly diagnosed patients, including subjects with IIIb cardiac stage (26%) or myeloma defining events (29%). Daratumumab was administered with bortezomib in 50 (56%) patients, lenalidomide in 31 (35%), and monotherapy in 7 (8%). The rate of serious adverse events was low (16%). The overall hematologic response rate was 75% with 52 (59%) patients attaining at least a very good partial response (VGPR) at six months. Amongst patients evaluable for organ response, the rate of cardiac and renal responses at 6 months was 31% and 21%, respectively. Comparing stage IIIb patients with the remaining ones, the rate of profound hematologic response was not significantly different (≥VGPR 57% vs. 59%, p 0.955) likewise the rate of cardiac (33% vs. 30%, p 0.340) and renal (40% vs. 16%, p 0.908) responses. Daratumumab‐based regimens demonstrated to be safe and effective in treatment‐naïve AL amyloidosis even in advanced stage disease. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
4. Gestione in Service dei Flussi Logistici in Ospedale: perché e a quali condizioni?
- Author
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Belvedere, Valeria, Cervi, L., D’Agnese, G., Damele, A., Palumbo, Michele, Pellegrino, Rossella, Polimeni, J., Russo, A., Villa, Stefano, Belvedere V. (ORCID:0000-0002-7748-5152), Palumbo M., Pellegrino R. (ORCID:0009-0002-9277-4937), Villa S. (ORCID:0000-0001-8111-3098), Belvedere, Valeria, Cervi, L., D’Agnese, G., Damele, A., Palumbo, Michele, Pellegrino, Rossella, Polimeni, J., Russo, A., Villa, Stefano, Belvedere V. (ORCID:0000-0002-7748-5152), Palumbo M., Pellegrino R. (ORCID:0009-0002-9277-4937), and Villa S. (ORCID:0000-0001-8111-3098)
- Abstract
Il presente studio, utilizzando differenti metodi d’indagine (survey, interviste semi-strutturate e studio osservazionale), analizza le condizioni organizzative e l'impatto sulla performance del modello di gestione in service dei flussi logistici.
- Published
- 2023
5. The Role of Ellagic Acid and Annona muricata in the Management of Human Papillomavirus (HPV)-Related Genital Lesions: A Systematic Review
- Author
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Cai, Tommaso, primary, Rizzo, Michele, additional, Liguori, Giovanni, additional, Palumbo, Michele, additional, Palmieri, Alessandro, additional, and Gallelli, Luca, additional
- Published
- 2023
- Full Text
- View/download PDF
6. Lenalidomide-based triplet regimens in first relapsed multiple myeloma patients: real-world evidence from a propensity score matched analysis
- Author
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Mangiacavalli, Silvia, primary, Cartia, Claudio Salvatore, additional, Galli, Monica, additional, Pezzatti, Sara, additional, Belotti, Angelo, additional, Fazio, Francesca, additional, Mina, Roberto, additional, Marcatti, Magda, additional, Cafro, Anna, additional, Zambello, Renato, additional, Paris, Laura, additional, Barilà, Gregorio, additional, Olivares, Cecilia, additional, Pompa, Alessandra, additional, Mazza, Rita, additional, Farina, Francesca, additional, Soldarini, Martina, additional, Benvenuti, Pietro, additional, Pagani, Giuseppina, additional, Palumbo, Michele, additional, Masoni, Valeria, additional, Ferretti, Virginia Valeria, additional, Klersy, Catherine, additional, Arcaini, Luca, additional, and Petrucci, Maria Teresa, additional
- Published
- 2022
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7. Prevention of Recurrent Urinary Tract Infections by Intravesical Administration of Hyaluronic Acid and Chondroitin Sulphate: A Placebo-Controlled Randomised Trial
- Author
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Damiano, Rocco, Quarto, Giuseppe, Bava, Ilaria, Ucciero, Giuseppe, De Domenico, Renato, Palumbo, Michele I., and Autorino, Riccardo
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- 2011
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8. Cómo el fenómeno de la corrupción afecta a nuestra sociedad: análisis, medición, ideas y teorías
- Author
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Palumbo, Michele, Hernández Cánovas, Ginés, Mol Gómez-Vázquez, Ana, and Economía, Contabilidad y Finanzas
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Corruption ,Contemporary society ,Desarrollo económico y social ,Economía Financiera y Contabilidad ,Economic and social development ,Sociedad contemporánea ,Economic sociology ,Corrupción ,Sociología económica ,5303 Contabilidad Económica - Abstract
A través este trabajo, se intenta describir un fenómeno social que afecta a nuestra sociedad bajo varios puntos de vista, extendiéndose heterogéneamente por todo el mundo. Se va a explicar como el fenómeno de la corrupción se articula en los países del mundo, demostrando que explota sobre todo diferentes situaciones y dinámicas sociales, pero también políticas y económicas para activarse y realizarse. El fenómeno corroe la sociedad en diferentes niveles de la economía tanto macroeconómicos como microeconómicos. En primer lugar, la corrupción es muy difícil de interpretar y evaluar efectivamente y la presencia (o la ausencia) de unos efectos económico-sociales, elecciones políticas e inversiones puedan cambiar considerablemente la posibilidad de desarrollo de este fenómeno. Luego, ha sido útil explicar y medir, a través gráficos oportunos, algunas relaciones entre el IPC de Trasparencia Internacional, es decir el Índice de Percepción de Corrupción o Corruption Percepetion Index en inglés, y varios parámetros macroeconómicos y también si el fenómeno afecte al crecimiento de un País. Los datos analizados sobre el IPC se refieran al año 2018. El apartado final analiza la rara “interpretación benéfica” de como la suministración de sobornos pueda ser leída en un contexto social y empresarial. El trabajo se concluye con la actualización de los últimos datos de Trasparencia Internacional sobre Italia e España y con una rápida consideración de los últimos eventos de actualidad en función de la pandemia de Covid-19 y sus posibles consecuencias. Facultad de Ciencias de la Empresa Universidad Politécnica de Cartagena
- Published
- 2020
9. Impact of the Addition of Daratumumab to the Standard Bortezomib-Thalidomide-Dexamethasone Regimen on Hematopoietic Stem Cell Mobilization and Collection, Post-Transplant Engraftment and Infectious Complications: A Case-Control Multicentre Real-Life Analysis
- Author
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Cavallaro, Gianluca, Galli, Monica, Paris, Laura, Stefanoni, Paola, Pavoni, Chiara, Mangiacavalli, Silvia, Masoni, Valeria, Palumbo, Michele, Pompa, Alessandra, Cafro, Anna Maria, Pezzatti, Sara, Crippa, Stefano, and Rambaldi, Alessandro
- Published
- 2023
- Full Text
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10. When Does the Cytokine Storm Begin in COVID-19 Patients? A Quick Score to Recognize It
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Cappanera, Stefano, primary, Palumbo, Michele, additional, Kwan, Sherman H., additional, Priante, Giulia, additional, Martella, Lucia Assunta, additional, Saraca, Lavinia Maria, additional, Sicari, Francesco, additional, Vernelli, Carlo, additional, Di Giuli, Cinzia, additional, Andreani, Paolo, additional, Mariottini, Alessandro, additional, Francucci, Marsilio, additional, Sensi, Emanuela, additional, Costantini, Monya, additional, Bruzzone, Paolo, additional, D’Andrea, Vito, additional, Gioia, Sara, additional, Cirocchi, Roberto, additional, and Tiri, Beatrice, additional
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- 2021
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11. Prevalence of acquired resistance mutations in a large cohort of perinatally infected HIV-1 patients
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Giacometti, Andrea, Butini, Luca, del Gobbo, Romana, Bagnarelli, Patrizia, Tacconi, Danilo, Corbelli, Giovanni, Zanussi, Stefania, Monno, Laura, Punzi, Grazia, Maggiolo, Franco, Calza, Leonardo, Carla Re, Maria, Pristera, Raffaele, Turconi, Paola, Mandas, Antonella, Tini, Sauro, Zoncada, Alessia, Paolini, Elisabetta, Amadio, Giorgio, Sighinolfi, Laura, Corsi, Paola, Galli, Luisa, Di Pietro, Massimo, Colao, Grazia, Tosti, Andrea, Setti, Maurizio, Bruzzone, Bianca, Di Biagio, Antonio, Cenderello, Giovanni, Trezzi, Michele, Orani, Anna, Arcidiacono, Irene, Degiuli, Alberto, De Gennaro, Michele, Chiodera, Alessandro, Scalzini, Alfredo, Palvarini, Loredana, Todaro, Giovanni, Rusconi, Stefano, Gismondo, Maria Rita, Micheli, Valeria, Biondi, Maria Luisa, Capetti, Amedeo, Meraviglia, Paola, Boeri, Enzo, Mussini, Cristina, Pecorari, Monica, Soria, Alessandro, Vecchi, Laura, Santirocchi, Maurizio, Brustia, Diego, Ravanini, Paolo, Dal Bello, Federico, Romano, Nino, Mancuso, Salvatrice, Calzetti, Carlo, Maserati, Renato, Filice, Gaetano, Baldanti, Fausto, Francisci, Daniela, Parruti, Giustino, Polilli, Ennio, Sacchini, Daria, Martinelli, Chiara, Consolini, Rita, Vatteroni, Linda, Vivarelli, Angela, Nerli, Alessandro, Lenzi, Lucia, Magnani, Giacomo, Ortolani, Patrizia, Andreoni, Massimo, Fimiani, Caterina, Palmisano, Lucia, Di Giambenedetto, Simona, Vullo, Vincenzo, Turriziani, Ombretta, Montano, Marco, Antinori, Andrea, Zaccarelli, Mauro, Dentone, Chiara, Gonnelli, Angela, De Luca, Andrea, Palumbo, Michele, Ghisetti, Valeria, Bonora, Stefano, Delle Foglie, Palma, Rossi, Cristina, Mondino, Vincenzo, Malena, Marina, Grossi, Paolo, Seminari, Elena, Poletti, Federica, Ungaro, R., Taramasso, L., Bruzzone, B., Vicenti, I., Galli, L., Borghi, V., Francisci, D., Pecorari, M., Zoncada, A., Callegaro, A.P., Paolini, E., Monno, L., Bonora, S., and Di Biagio, A.
- Published
- 2019
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12. Detection of drug resistance mutations at low plasma HIV-1 RNA load in a European multicentre cohort study
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Prosperi, Mattia C. F., Mackie, Nicola, Di Giambenedetto, Simona, Zazzi, Maurizio, Camacho, Ricardo, Fanti, Iuri, Torti, Carlo, Sönnerborg, Anders, Kaiser, Rolf, Codoñer, Francisco M., Van Laethem, Kristel, Bansi, Loveleen, van de Vijver, David A. M. C., Geretti, Anna Maria, De Luca, Andrea, Giacometti, Andrea, Butini, Luca, del Gobbo, Romana, Menzo, Stefano, Tacconi, Danilo, Corbelli, Giovanni, Zanussi, Stefania, Monno, Laura, Punzi, Grazia, Maggiolo, Franco, Callegaro, Annapaola, Calza, Leonardo, Carla Re, Maria, Pristerà, Raffaele, Turconi, Paola, Mandas, Antonella, Tini, Sauro, Zoncada, Alessia, Paolini, Elisabetta, Amadio, Giorgio, Sighinolfi, Laura, Zuccati, Giuliano, Morfini, Massimo, Manetti, Roberto, Corsi, Paola, Galli, Luisa, Di Pietro, Massimo, Bartalesi, Filippo, Colao, Grazia, Tosti, Andrea, Di Biagio, Antonio, Setti, Maurizio, Bruzzone, Bianca, Penco, Giovanni, Trezzi, Michele, Orani, Anna, Pardelli, Riccardo, De Gennaro, Michele, Chiodera, Alessandro, Scalzini, Alfredo, Palvarini, Loredana, Almi, Paolo, Todaro, Giovanni, dʼArminio Monforte, Antonella, Cicconi, Paola, Rusconi, Stefano, Gismondo, Maria Rita, Gismondo, Maria Rita, Micheli, Valeria, Biondi, Maria Luisa, Gianotti, Nicola, Capetti, Amedeo, Meraviglia, Paola, Boeri, Enzo, Mussini, Cristina, Pecorari, Monica, Soria, Alessandro, Vecchi, Laura, Santirocchi, Maurizio, Brustia, Diego, Ravanini, Paolo, Bello, Federico Dal, Romano, Nino, Mancuso, Salvatrice, Calzetti, Carlo, Maserati, Renato, Filice, Gaetano, Baldanti, Fausto, Francisci, Daniela, Parruti, Giustino, Polilli, Ennio, Sacchini, Daria, Martinelli, Chiara, Consolini, Rita, Vatteroni, Linda, Vivarelli, Angela, Dionisio, Daniele, Nerli, Alessandro, Lenzi, Lucia, Magnani, Giacomo, Ortolani, Patrizia, Andreoni, Massimo, Palamara, Guido, Fimiani, Caterina, Palmisano, Lucia, De Luca, Andrea, Fadda, Giovanni, Vullo, Vincenzo, Turriziani, Ombretta, Montano, Marco, Cenderello, Giovanni, Gonnelli, Angela, Zazzi, Maurizio, Palumbo, Michele, Ghisetti, Valeria, Bonora, Stefano, Foglie, Palma Delle, Rossi, Cristina, Grossi, Paolo, Seminari, Elena, Poletti, Federica, Mondino, Vincenzo, Malena, Marina, Lattuada, Emanuela, Lengauer, Thomas, Däumer, Martin, Hoffmann, Daniel, Kaiser, Rolf, Schülter, Eugen, Müller, Claudia, Oette, Mark, Reuter, Stefan, Esser, Stefan, Fätkenheuer, Gerd, Rockstroh, Jürgen, van de Vijver, David AMC, Incardona, Francesca, Rosen-Zvi, Michal, Lengauer, Thomas, Camacho, Ricardo, Clotet, Bonaventura, Thalme, Anders, Svedhem, Veronica, Bratt, Göran, Gargiulo, Franco, Lapadula, Giuseppe, Manca, Nino, Paraninfo, Giuseppe, Quiros-Roldan, Eugenia, Carosi, Giampiero, Castelnuovo, Filippo, Vandamme, Anne-Mieke, Van Laethem, Kristel, Van Wijngaerden, Eric, Ainsworth, Jonathan, Anderson, Jane, Babiker, Abdel, Dunn, David, Easterbrook, Philippa, Fisher, Martin, Gazzard, Brian, Garrett, Nigel, Gilson, Richard, Gompels, Mark, Hill, Teresa, Johnson, Margaret, Leen, Clifford, Orkin, Chloe, Phillips, Andrew, Pillay, Deenan, Porter, Kholoud, Post, Frank, Sabin, Caroline, Sadiq, Tariq, Schwenk, Achim, Walsh, John, Delpech, Valerie, Palfreeman, Adrian, Dunn, David, Glabay, Adam, Porter, Kholoud, Bansi, Loveleen, Hill, Teresa, Phillips, Andrew, Sabin, Caroline, Orkin, Chloe, Garrett, Nigel, Lynch, Janet, Hand, James, de Souza, Carl, Fisher, Martin, Perry, Nicky, Tilbury, Stuart, Churchill, Duncan, Gazzard, Brian, Nelson, Mark, Waxman, Matthew, Mandalia, Sundhiya, Delpech, Valerie, Anderson, Jane, Kall, Meaghan, Post, Frank, Korat, Hardik, Taylor, Chris, Ibrahim, Fowzia, Campbell, Lucy, Easterbrook, Philippa, Babiker, Abdel, Dunn, David, Glabay, Adam, Porter, Kholoud, Gilson, Richard, James, Laura, Brima, Nataliya, Williams, Ian, Schwenk, Achim, Johnson, Margaret, Youle, Mike, Lampe, Fiona, Smith, Colette, Grabowska, Helen, Chaloner, Clinton, Puradiredja, Dewi Ismajani, Bansi, Loveleen, Hill, Teresa, Phillips, Andrew, Sabin, Caroline, Walsh, John, Weber, Jonathan, Ramzan, Farhan, Carder, Mark, Leen, Clifford, Wilson, Alan, Gompels, Mark, Dooley, Debbie, Palfreeman, Adrian, Anderson, Jane, Asboe, David, Pozniak, Anton, Cameron, Sheila, Cane, Patricia, Chadwick, David, Churchill, Duncan, Clark, Duncan, Collins, Simon, Delpech, Valerie, Pillay, Deenan, Lazarus, Linda, Dunn, David, Dolling, David, Fearnhill, Esther, Castro, Hannah, Porter, Kholoud, Coughlin, Kate, Dolling, David, Zuckerman, Mark, Anna Maria, Geretti, Booth, Clare, Goldberg, David, Gompels, Mark, Hale, Antony, Kaye, Steve, Kellam, Paul, Leigh-Brown, Andrew, Mackie, Nicola, Orkin, Chloe, Pillay, Deenan, Phillips, Andrew, Sabin, Caroline, Smit, Erasmus, Templeton, Kate, Tilston, Peter, Tong, William, Williams, Ian, Zhang, Hongyi, Zhang, Hongyi, Clark, Duncan, Ushiro-Lumb, Ines, Oliver, Tony, Bibby, David, Mitchell, Suzanne, Smit, Erasmus, Mbisa, Tamyo, Wildfire, Adrian, Tandy, Richard, Shepherd, Jill, Chadwick, David, MacLean, Alasdair, Tong, William, Bennett, Diane, Hopkins, Mark, Tilston, Peter, Booth, Clare, Garcia-Diaz, Ana, Kaye, Steve, and Kirk, Stuart
- Published
- 2011
- Full Text
- View/download PDF
13. Cómo el fenómeno de la corrupción afecta a nuestra sociedad: análisis, medición, ideas y teorías.
- Author
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Hernández Cánovas, Ginés, Mol Gómez-Vázquez, Ana, Economía, Contabilidad y Finanzas, Palumbo, Michele, Hernández Cánovas, Ginés, Mol Gómez-Vázquez, Ana, Economía, Contabilidad y Finanzas, and Palumbo, Michele
- Abstract
A través este trabajo, se intenta describir un fenómeno social que afecta a nuestra sociedad bajo varios puntos de vista, extendiéndose heterogéneamente por todo el mundo. Se va a explicar como el fenómeno de la corrupción se articula en los países del mundo, demostrando que explota sobre todo diferentes situaciones y dinámicas sociales, pero también políticas y económicas para activarse y realizarse. El fenómeno corroe la sociedad en diferentes niveles de la economía tanto macroeconómicos como microeconómicos. En primer lugar, la corrupción es muy difícil de interpretar y evaluar efectivamente y la presencia (o la ausencia) de unos efectos económico-sociales, elecciones políticas e inversiones puedan cambiar considerablemente la posibilidad de desarrollo de este fenómeno. Luego, ha sido útil explicar y medir, a través gráficos oportunos, algunas relaciones entre el IPC de Trasparencia Internacional, es decir el Índice de Percepción de Corrupción o Corruption Percepetion Index en inglés, y varios parámetros macroeconómicos y también si el fenómeno afecte al crecimiento de un País. Los datos analizados sobre el IPC se refieran al año 2018. El apartado final analiza la rara “interpretación benéfica” de como la suministración de sobornos pueda ser leída en un contexto social y empresarial. El trabajo se concluye con la actualización de los últimos datos de Trasparencia Internacional sobre Italia e España y con una rápida consideración de los últimos eventos de actualidad en función de la pandemia de Covid-19 y sus posibles consecuencias.
- Published
- 2020
14. Prevalence of acquired resistance mutations in a large cohort of perinatally infected HIV-1 patients
- Author
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Ungaro, R., primary, Taramasso, L., additional, Bruzzone, B., additional, Vicenti, I., additional, Galli, L., additional, Borghi, V., additional, Francisci, D., additional, Pecorari, M., additional, Zoncada, A., additional, Callegaro, A.P., additional, Paolini, E., additional, Monno, L., additional, Bonora, S., additional, Di Biagio, A., additional, Giacometti, Andrea, additional, Butini, Luca, additional, del Gobbo, Romana, additional, Bagnarelli, Patrizia, additional, Tacconi, Danilo, additional, Corbelli, Giovanni, additional, Zanussi, Stefania, additional, Monno, Laura, additional, Punzi, Grazia, additional, Maggiolo, Franco, additional, Calza, Leonardo, additional, Carla Re, Maria, additional, Pristera, Raffaele, additional, Turconi, Paola, additional, Mandas, Antonella, additional, Tini, Sauro, additional, Zoncada, Alessia, additional, Paolini, Elisabetta, additional, Amadio, Giorgio, additional, Sighinolfi, Laura, additional, Corsi, Paola, additional, Galli, Luisa, additional, Di Pietro, Massimo, additional, Colao, Grazia, additional, Tosti, Andrea, additional, Setti, Maurizio, additional, Bruzzone, Bianca, additional, Di Biagio, Antonio, additional, Cenderello, Giovanni, additional, Trezzi, Michele, additional, Orani, Anna, additional, Arcidiacono, Irene, additional, Degiuli, Alberto, additional, De Gennaro, Michele, additional, Chiodera, Alessandro, additional, Scalzini, Alfredo, additional, Palvarini, Loredana, additional, Todaro, Giovanni, additional, Rusconi, Stefano, additional, Gismondo, Maria Rita, additional, Micheli, Valeria, additional, Biondi, Maria Luisa, additional, Capetti, Amedeo, additional, Meraviglia, Paola, additional, Boeri, Enzo, additional, Mussini, Cristina, additional, Pecorari, Monica, additional, Soria, Alessandro, additional, Vecchi, Laura, additional, Santirocchi, Maurizio, additional, Brustia, Diego, additional, Ravanini, Paolo, additional, Dal Bello, Federico, additional, Romano, Nino, additional, Mancuso, Salvatrice, additional, Calzetti, Carlo, additional, Maserati, Renato, additional, Filice, Gaetano, additional, Baldanti, Fausto, additional, Francisci, Daniela, additional, Parruti, Giustino, additional, Polilli, Ennio, additional, Sacchini, Daria, additional, Martinelli, Chiara, additional, Consolini, Rita, additional, Vatteroni, Linda, additional, Vivarelli, Angela, additional, Nerli, Alessandro, additional, Lenzi, Lucia, additional, Magnani, Giacomo, additional, Ortolani, Patrizia, additional, Andreoni, Massimo, additional, Fimiani, Caterina, additional, Palmisano, Lucia, additional, Di Giambenedetto, Simona, additional, Vullo, Vincenzo, additional, Turriziani, Ombretta, additional, Montano, Marco, additional, Antinori, Andrea, additional, Zaccarelli, Mauro, additional, Dentone, Chiara, additional, Gonnelli, Angela, additional, De Luca, Andrea, additional, Palumbo, Michele, additional, Ghisetti, Valeria, additional, Bonora, Stefano, additional, Delle Foglie, Palma, additional, Rossi, Cristina, additional, Mondino, Vincenzo, additional, Malena, Marina, additional, Grossi, Paolo, additional, Seminari, Elena, additional, and Poletti, Federica, additional
- Published
- 2019
- Full Text
- View/download PDF
15. The role of baseline HIV-1 RNA, drug resistance, and regimen type as determinants of response to first-line antiretroviral therapy
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Di Biagio, Antonio, Rusconi, Stefano, Marzocchetti, Angela, Signori, Alessio, Schiavetti, Irene, Bruzzone, Bianca, Monno, Laura, Punzi, Grazia, Colao, Maria Grazia, Penco, Giovanni, Zazzi, Maurizio, De Luca, Andrea, Giacometti, Andrea, Butini, Luca, Del Gobbo, Romana, Bagnarelli, Patrizia, Tacconi, Danilo, Corbelli, Giovanni, Zanussi, Stefania, Maggiolo, Franco, Callegaro, Annapaola, Calza, Leonardo, Maria Carla, Re, Pristerà, Raffaele, Turconi, Paola, Mandas, Antonella, Pozzo, Alessandra, Simeone, Nuccia, Tini, Sauro, Zoncada, Alessia, Paolini, Elisabetta, Amadio, Giorgio, Sighinolfi, Laura, Zuccati, Giuliano, Morfini, Massimo, Manetti, Roberto, Corsi, Paola, Galli, Luisa, Di Pietro, Massimo, Bartalesi, Filippo, Colao, Grazia, Tosti, Andrea, Setti, Maurizio, Trezzi, Michele, Bonfanti, Paolo, Pardelli, Riccardo, Arcidiacono, Irene, Degiuli, Alberto, De Gennaro, Michele, Chiodera, Alessandro, Scalzini, Alfredo, Palvarini, Loredana, Almi, Paolo, Todaro, Giovanni, Cicconi, Paola, Gismondo, Maria Rita, Micheli, Valeria, Biondi, Maria Luisa, Gianotti, Nicola, Capetti, Amedeo, Meraviglia, Paola, Boeri, Enzo, Mussini, Cristina, Pecorari, Monica, Soria, Alessandro, Malandrin, Sergio, Santirocchi, Maurizio, Brustia, Diego, Ravanini, Paolo, Dal Bello, Federico, Romano, Nino, Mineo, Maurizio, Mancuso, Salvatrice, Calzetti, Carlo, Maserati, Renato, Filice, Gaetano, Baldanti, Fausto, Francisci, Daniela, Parruti, Giustino, Polilli, Ennio, Sacchini, Daria, Martinelli, Chiara, Consolini, Rita, Vatteroni, Linda, Vivarelli, Angela, Nerli, Alessandro, Lenzi, Lucia, Magnani, Giacomo, Ortolani, Patrizia, Andreoni, Massimo, Palamara, Guido, Fimiani, Caterina, Palmisano, Lucia, Di Gaimbenedetto, Simona, Colafigli, Manuela, Vullo, Vincenzo, Turriziani, Ombretta, Montano, Marco, Senatore, Cataldo, Dentone, Chiara, Gonnelli, Angela, Palumbo, Michele, Ghisetti, Valeria, Bonora, Stefano, Foglie, Palma Delle, Rossi, Cristina, Grossi, Paolo, Seminari, Elena, Poletti, Federica, Mondino, Vincenzo, and Malena, Marina
- Subjects
Adult ,Male ,Adolescent ,Genotype ,Antiretroviral Therapy ,HIV Infections ,Settore MED/17 - MALATTIE INFETTIVE ,wGSS ,Young Adult ,Virology ,Antiretroviral Therapy, Highly Active ,Drug Resistance, Viral ,80 and over ,Humans ,Highly Active ,HIV-1 RNA ,Viral ,Longitudinal Studies ,CD4 ,Drug regimen ,Drug resistance ,N(n)RTI backbone ,WGSS ,Infectious Diseases ,Aged ,Aged, 80 and over ,Anti-Retroviral Agents ,CD4 Lymphocyte Count ,Female ,HIV-1 ,Italy ,Middle Aged ,RNA, Viral ,Retrospective Studies ,Treatment Outcome ,Viral Load ,drug regimen ,drug resistance ,RNA - Abstract
The factors influencing virological response to first-line combined antiretroviral therapy (cART) in an Italian cohort of HIV-1-infected patients were examined. Eligible patients were those enrolled in a national prospective observational cohort (Antiretroviral Resistance Cohort Analysis), starting first-line cART between 2001 and 2011 and who had at least one follow-up of HIV-1 RNA. The primary endpoint was virological success, defined as the first viral load50 copies/ml. Time to events were analyzed by Kaplan-Meier analysis and Cox proportional hazard model. One thousand three hundred five patients met the study inclusion criteria. In a multivariable model adjusting for transmission mode, presence of transmitted drug resistance, baseline CD4(+) cell count, viral subtype, and type of NRTI backbone employed, independent predictors of virological success were higher baseline viral load (≥500,000 vs.100,000 HR 0.52; P 0.001), a weighted genotypic susceptibility score (wGSS)3 (HR 0.58; P = 0.003), male sex (HR 0.76 P = 0.001), and type of initial third drug employed (integrase inhibitor vs. boosted protease inhibitors HR 3.23; P 0.001). In the subset with HIV-1 RNA100,000 copies/ml, virologic success was only associated with the use of integrase inhibitors in the first cART regimen. Independent predictors of immunological success were baseline CD4(+) cell count and wGSS3. High baseline HIV-1 RNA, predicted activity of the first-line regimen based on genotypic resistance testing, gender, and use of new agents were found to predict time to achieve virological success. The type of initial nucleoside analog backbone was not found to predict virological response.
- Published
- 2014
16. Utility of kinematic MRI to evaluation of the female pelvic floor: comparison with conventional defecography
- Author
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Palumbo, Michele
- Subjects
Abdomen ,MR ,Pelvis ,MR-Functional imaging ,Defecography - Abstract
Purpose Methods and Materials Results Conclusion References Personal Information, Purpose: Pelvic floor dysfunction is a heterogeneous group of female disorders that are very common in the general population and presenting with pelvic pain, pressure, dyspareunia, incontinence, incomplete emptying, and gross organ protrusion. The true...
- Published
- 2013
- Full Text
- View/download PDF
17. Relaxometry with magnetic resonance in myocardium of ventricle left: the parameter R2 in volunteers healthy and athletes in terms of rest
- Author
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Palumbo, Michele
- Subjects
MR ,Imaging sequences ,Cardiac ,MR-Functional imaging - Abstract
Purpose Methods and Materials Results Conclusion References Personal Information, Purpose: BOLD-MRI (Blood Oxygenation Level Dependent sequences in Magnetic Resonance Imaging) represents a non-invasive method to study the oxygen distribution in parenchymas. This method uses the deoxygenated hemoglobin property to cause spin dephasing of...
- Published
- 2013
- Full Text
- View/download PDF
18. Corrigendum to “Prevention of Recurrent Urinary Tract Infections by Intravesical Administration of Hyaluronic Acid and Chondroitin Sulphate: A Placebo-Controlled Randomised Trial [Eur Urol 2011;59:645–51]
- Author
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Damiano, Rocco, primary, Quarto, Giuseppe, additional, Bava, Ilaria, additional, Ucciero, Giuseppe, additional, De Domenico, Renato, additional, Palumbo, Michele I., additional, and Autorino, Riccardo, additional
- Published
- 2011
- Full Text
- View/download PDF
19. Mimêsis teorizzata e mimêsis realizzata nel Sofista platonico
- Author
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Lidia Palumbo, Stephen Halliwell, Michael Erler, Andrea Capra, Anna Pavani, Laura Candiotto, Elenio Cecchini, Justin Vlastis, Irmgard Maennlein-Robert, Lidia Palumbo, Michele Abbate, Alexandra V.Alvan Leon, Benedikt Strobel, Francesco Fronterotta, Antonino Spinelli, José Antonio Giménez, Julia Pfefferkon, Julia Pfefferkorn, Antonino Spinelli, and Palumbo, Lidia
- Subjects
Plato, Mimesis, Dialogue, Image - Abstract
This paper aims at discussing Platonic examples of mimesis in the Sophist, by trying to identify the mimetic figures that show to the reader, in a vivid way, what the characters of the dialogue abstractly theorize. All Platonic dialogues are mimetic, but the Sophist is a privileged point of observation of their “mimeticity” because in the Sophist one of the characters explains what mimesis is, how it works. In addition, such a character does not simply explain this abstractly, but puts mimetic figures in front of the eyes of his interlocutor, just as Plato does with his reader. The question of difference is linked to that of mimesis and plays a crucial role in the Sophist. This question, too, is not only discussed at length but is also presented in front of the eyes of the reader thanks to the figure of the Eleatic Stranger who embodies the difference and makes it visible, just as the Sophist makes visible the misleading nature of not-being. This dialogue, with the aporiai of diairesis, stages the difficulty of drawing the figure of the sophist, who is never staged as a character, but is always faced as a problem.
- Published
- 2021
- Full Text
- View/download PDF
20. [A cause of acute renal dysfunction: a giant bladder diverticulum]
- Author
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Rivoli, L., Leonardi, G., Scafuro, C., Ucciero, G., Palumbo, M., Galluccio, G., Mariadelina Simeoni, Capria, M., Fuiano, G., Rivoli, Laura, Leonardi, Giuseppe, Scafuro, Chiara, Ucciero, Giuseppe, Palumbo, Michele, Galluccio, Giuseppe, Simeoni, Mariadelina, Capria, Maria, and Fuiano, Giorgio
- Subjects
Male ,Hydronephrosi ,obstructive nephropathy ,Bladder diverticulum ,Prostatic Hyperplasia ,Urinary Bladder Diseases ,Acute Kidney Injury ,Diverticulum ,AKI ,Ascite ,Edema ,Aged ,Human ,Ultrasonography - Abstract
We describe the case of a previously 77-year-old man who accessed in our Nephrology Unit for acute kidney injury (AKI) on chronic kidney disease (CKD), gastric discomfort and vague urinary symptoms with apparently preserved diuresis and suspected "ascites". Physical examination confirmed the presence of abdominal effusion, even though ultrasound abdominal examination revealed the presence of a giant diverticular urinary bladder with bilateral hydronephrosis. We discuss the diagnostic and therapeutic approach of these rare complications by briefly reviewing the technical aspects and the possible consequences.
- Published
- 2018
21. Feasibility of a Biomarker-Based Screening for Pre-Symptomatic AL Amyloidosis in Patients With Intermediate/High-Risk MGUS.
- Author
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Mangiacavalli S, Milani P, Cartia CS, Varettoni M, Palumbo M, Basset M, Masoni V, Nuvolone M, Foli A, Ferretti VV, Merlini G, Arcaini L, and Palladini G
- Subjects
- Humans, Male, Female, Middle Aged, Aged, Immunoglobulin Light-chain Amyloidosis diagnosis, Immunoglobulin Light-chain Amyloidosis blood, Biomarkers, Monoclonal Gammopathy of Undetermined Significance diagnosis, Monoclonal Gammopathy of Undetermined Significance complications, Monoclonal Gammopathy of Undetermined Significance blood, Feasibility Studies
- Abstract
Biomarker-based screening enables early detection of AL amyloidosis in intermediate/high-risk MGUS patients. Our study shows that identifying pre-symptomatic AL through biomarker longitudinal monitoring allows early treatment, leading to significant organ function recovery., (© 2024 The Author(s). American Journal of Hematology published by Wiley Periodicals LLC.)
- Published
- 2025
- Full Text
- View/download PDF
22. Lenalidomide-based triplet regimens in first relapsed multiple myeloma patients: real-world evidence from a propensity score matched analysis.
- Author
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Mangiacavalli S, Cartia CS, Galli M, Pezzatti S, Belotti A, Fazio F, Mina R, Marcatti M, Cafro A, Zambello R, Paris L, Barilà G, Olivares C, Pompa A, Mazza R, Farina F, Soldarini M, Benvenuti P, Pagani G, Palumbo M, Masoni V, Ferretti VV, Klersy C, Arcaini L, and Petrucci MT
- Subjects
- Humans, Lenalidomide therapeutic use, Propensity Score, Neoplasm Recurrence, Local drug therapy, Dexamethasone therapeutic use, Antineoplastic Combined Chemotherapy Protocols adverse effects, Multiple Myeloma drug therapy
- Abstract
Lenalidomide and dexamethasone (Rd)-based triplets, in particular carfilzomib-Rd (KRd) and daratumumab-Rd (DaraRd), represent a standard of care in lenalidomide-sensitive multiple myeloma (MM) patients in first relapse. Meta-analysis of randomized clinical trials (RCT), suggested better outcome with DaraRd. Trying to address this issue in clinical practice, we collected data of 430 consecutive MM patients addressed to Rd-based triplets in first relapse between January 2017 and March 2021. Overall, the most common used regimen was DaraRd, chosen in almost half of the cases (54.4%), followed by KRd (34.6%). Different triplets were used much less commonly. In an attempt to limit the imbalance of a retrospective analysis, we conducted a propensity score matching (PSM) comparison between DaraRd and KRd. After PSM, efficacy of DaraRd versus KRd was similar in terms of overall-response rate (ORR) (OR: 0.9, P=0.685) as well as of very good partial response (VGPR) or better (OR: 0.9, P=0.582). The median progression-free survival (PFS) was significantly longer for DaraRd (29.8 vs. 22.5 months; P=0.028). DaraRd was tolerated better, registering a lower rate of grade 3-4 non-hematological toxicity (OR: 0.4, P<0.001). With the limitations of any retrospective analysis, our real-life PSM comparison between DaraRd and KRd, in first-relapse MM patients, showed better tolerability and prolonged PFS of DaraRd, although with some gaps of performance, in particular of DaraRd, with respect to RCT. Carfilzomib-containing regimens, like KRd, still remain a valid second-line option in the emerging scenario of first-line daratumumab-based therapy.
- Published
- 2023
- Full Text
- View/download PDF
23. [A cause of acute renal dysfunction: a giant bladder diverticulum].
- Author
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Rivoli L, Leonardi G, Scafuro C, Ucciero G, Palumbo M, Galluccio G, Simeoni M, Capria M, and Fuiano G
- Subjects
- Aged, Ascites diagnostic imaging, Ascites etiology, Diverticulum diagnostic imaging, Edema etiology, Humans, Hydronephrosis etiology, Male, Prostatic Hyperplasia complications, Prostatic Hyperplasia diagnostic imaging, Ultrasonography, Urinary Bladder Diseases diagnostic imaging, Acute Kidney Injury etiology, Diverticulum complications, Urinary Bladder Diseases complications
- Abstract
We describe the case of a previously 77-year-old man who accessed in our Nephrology Unit for acute kidney injury (AKI) on chronic kidney disease (CKD), gastric discomfort and vague urinary symptoms with apparently preserved diuresis and suspected "ascites". Physical examination confirmed the presence of abdominal effusion, even though ultrasound abdominal examination revealed the presence of a giant diverticular urinary bladder with bilateral hydronephrosis. We discuss the diagnostic and therapeutic approach of these rare complications by briefly reviewing the technical aspects and the possible consequences., (Copyright by Società Italiana di Nefrologia SIN, Rome, Italy.)
- Published
- 2018
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