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16. Cardiovascular magnetic resonance myocardial feature tracking detects quantitative wall motion during dobutamine stress

Author

Beerbaum Philipp, Bigalke Boris, Makowski Marcus R, Parish Victoria, Gribben Paul, Danford David A, Kutty Shelby, Padiyath Asif, Schuster Andreas, and Nagel Eike

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Abstract Background Dobutamine stress cardiovascular magnetic resonance (DS-CMR) is an established tool to assess hibernating myocardium and ischemia. Analysis is typically based on visual assessment with considerable operator dependency. CMR myocardial feature tracking (CMR-FT) is a recently introduced technique for tissue voxel motion tracking on standard steady-state free precession (SSFP) images to derive circumferential and radial myocardial mechanics. We sought to determine the feasibility and reproducibility of CMR-FT for quantitative wall motion assessment during intermediate dose DS-CMR. Methods 10 healthy subjects were studied at 1.5 Tesla. Myocardial strain parameters were derived from SSFP cine images using dedicated CMR-FT software (Diogenes MRI prototype; Tomtec; Germany). Right ventricular (RV) and left ventricular (LV) longitudinal strain (EllRV and EllLV) and LV long-axis radial strain (ErrLAX) were derived from a 4-chamber view at rest. LV short-axis circumferential strain (EccSAX) and ErrSAX; LV ejection fraction (EF) and volumes were analyzed at rest and during dobutamine stress (10 and 20 μg · kg-1· min-1). Results In all volunteers strain parameters could be derived from the SSFP images at rest and stress. EccSAX values showed significantly increased contraction with DSMR (rest: -24.1 ± 6.7; 10 μg: -32.7 ± 11.4; 20 μg: -39.2 ± 15.2; p < 0.05). ErrSAX increased significantly with dobutamine (rest: 19.6 ± 14.6; 10 μg: 31.8 ± 20.9; 20 μg: 42.4 ± 25.5; p < 0.05). In parallel with these changes; EF increased significantly with dobutamine (rest: 56.9 ± 4.4%; 10 μg: 70.7 ± 8.1; 20 μg: 76.8 ± 4.6; p < 0.05). Observer variability was best for LV circumferential strain (EccSAX ) and worst for RV longitudinal strain (EllRV) as determined by 95% confidence intervals of the difference. Conclusions CMR-FT reliably detects quantitative wall motion and strain derived from SSFP cine imaging that corresponds to inotropic stimulation. The current implementation may need improvement to reduce observer-induced variance. Within a given CMR lab; this novel technique holds promise of easy and fast quantification of wall mechanics and strain.

Published
2011
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23. Removal of a retained intracardiac radiolucent guidewire fragment using an Atrieve™ vascular snare using combined fluoroscopy and transesophageal echocardiography guidance in an infant.

Author

Padiyath, Asif, Fontenot, Eudice E., and Abraham, Boban P.

Abstract

Retained intravascular foreign body is a well-known complication of central venous access placement in children as well as adults. Most of these foreign bodies are radio-opaque and hence are removed under fuoroscopy guidance. In our case, we describe the removal of an intracardiac radiolucent foreign body in an infant utilizing a combination technique - transesophageal echocardiogram and fluoroscopy. [ABSTRACT FROM AUTHOR]

Published
2017
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26. REAL TIME THREE DIMENSIONAL TRANSESOPHAGEAL ECHOCARDIOGRAPHY COUPLED WITH DIAGNOSTIC CATHETERIZATION TO DETERMINE LEFT VENTRICULAR PRESSURE-VOLUME RELATIONSHIPS AND MYOCONTRACTILITY

Author

Kutty, Shelby, primary, Nordmeyer, Sarah, additional, Padiyath, Asif, additional, Gribben, Paul, additional, Li, Ling, additional, Gao, Shunji, additional, Rangamani, Sheela, additional, Drvol, Lucas, additional, Lof, John, additional, Danford, David, additional, and Kuehne, Titus, additional

Published
2012
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