472 results on '"Padilla B"'
Search Results
2. Erratum: Direct Mechanical Detection and Measurement of Wave-Matter Orbital Angular Momentum Transfer by Nondissipative Vortex Mode Conversion [Phys. Rev. Lett. 123 , 244301 (2019)]
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Sanchez-Padilla, B., primary, Jonusauskas, L., additional, Malinauskas, M., additional, Wunenburger, R., additional, and Brasselet, E., additional
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- 2024
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3. Obtaining an Ent35-MccV derivative with mutated hinge region that exhibits increased activity against Listeria monocytogenes and Escherichia coli
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Navarro, S. A., Lanza, L., Colombo, N. S. Ríos, de Ullivarri, M. Fernandez, Acuña, L., Sosa-Padilla, B., Picariello, G., Bellomio, A., and Chalón, Miriam C.
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- 2019
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4. Rhodomyrtone decreases Staphylococcus aureus SigB activity during exponentially growing phase and inhibits haemolytic activity within membrane vesicles
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Jover, A., Barcenilla, F., García, M., Pujol, M., Gasch, O., Domínguez, M.A., Camoez, M., Dueñas, C., Ojeda, E., Martínez, J.A., Marco, F., Chaves, F., Lagarde, M., López-Medrano, F., Montejo, J.M., Bereciertua, E., Hernández, J.L., von Wichmann, M.Á., Goenaga, A., García-Arenzana, J.M., Padilla, B., Padilla, C., Cercenado, E., García-Prado, G., Tapiol, J., Horcajada, J.P., Montero, M., Salvadó, M., Arnáiz, A., Fernández, C., Calbo, E., Xercavins, M., Granados, A., Fontanals, D., Pintado, V., Loza, E., Torre-Cisneros, J., Lara, R., Rodríguez-López, F., Natera, C., Blanco, J.R., Olarte, I., Benito, N., Mirelis, B., Murillas, J., Ruiz de Gopegui, E., Espejo, H., Morera, M.A., Rodríguez-Baño, J., López-Cortés, L.E., Pascual, A., Martín, C., Lepe, J.A., Molina, J., Sordé, R., Almirante, B., Larrosa, N., Mitsuwan, Watcharapong, Jiménez-Munguía, Irene, Visutthi, Monton, Sianglum, Wipawadee, Rodríguez-Ortega, Manuel J., and Voravuthikunchai, Supayang P.
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- 2019
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5. Análisis de Datos COVID-19 Utilizando Algoritmos de Inteligencia Artificial
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Martínez-Escobar, A Elda Y., primary, Celaya-Padilla, B. José M., additional, Martínez-Torteya, Antonio, additional, Sustaita-Torres, C. Ireri A., additional, Murillo-Soto, Manuel A., additional, and Galván-Tejada, Jorge I., additional
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- 2023
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6. Tumor de células granulares de partes blandas: hallazgos en resonancia magnética
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Iglesias-Hidalgo, G., primary, Lopez-Maseda, A., additional, Zaldumbide-Dueñas, L., additional, and Canteli-Padilla, B., additional
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- 2023
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7. Granular cell tumor of soft tissues: MR findings
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Iglesias-Hidalgo, G., primary, Lopez-Maseda, A., additional, Zaldumbide-Dueñas, L., additional, and Canteli-Padilla, B., additional
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- 2023
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8. No evidence of increased ocular involvement in candidemic patients initially treated with echinocandins
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Muñoz, P., Vena, A., Padilla, B., Valerio, M., Sanchez, M.I., Puig-Asensio, M., Fortún, J., Fernández-Ruiz, M., Merino, P., Losa, J.E., Loza, A., Rivas, R.A., and Bouza, E.
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- 2017
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9. AB0957 IMPROVEMENTS IN PATIENT-REPORTED OUTCOMES AMONG PATIENTS WITH RESOLUTION OF ENTHESITIS AND/OR DACTYLITIS: POST HOC ANALYSES FROM THE KEEPSAKE 1 AND 2 TRIALS OF RISANKIZUMAB IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS
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Kwatra, S., primary, Khattri, S., additional, Amin, A., additional, Liu, R., additional, Padilla, B., additional, Soliman, A. M., additional, Kaplan, B., additional, and Mcgonagle, D., additional
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- 2023
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10. POS1524 DURABLE CLINICALLY-MEANINGFUL IMPROVEMENTS IN HEALTH-RELATED QUALITY OF LIFE, FATIGUE, PAIN, AND WORK PRODUCTIVITY AMONG PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS TREATED WITH RISANKIZUMAB AT WEEK 100
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Kristensen, L. E., primary, Soliman, A. M., additional, Padilla, B., additional, Papp, K., additional, and Ostor, A., additional
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- 2023
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11. POS1543 EFFICACY OF RISANKIZUMAB IN THE TREATMENT OF PsA PATIENTS WITH LIMITED AND EXTENSIVE JOINT INVOLVEMENT
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Ogdie, A., primary, Ritchlin, C. T., additional, Gladman, D. D., additional, M R Nakasato, P., additional, Liu, R., additional, Kaufmann, C., additional, Padilla, B., additional, and Gossec, L., additional
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- 2023
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12. Single‐Step 3D Printing of Micro‐Optics with Adjustable Refractive Index by Ultrafast Laser Nanolithography
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Gonzalez‐Hernandez, D., primary, Sanchez‐Padilla, B., additional, Gailevičius, D., additional, Thodika, S. Chandran, additional, Juodkazis, S., additional, Brasselet, E., additional, and Malinauskas, M., additional
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- 2023
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13. A Comparison of Science Between Similar GDP Countries: Spain, Mexico and Indonesia
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Barrera, Gonzalo Irving, Macías Padilla, B. Alan, and Rosales Rodríguez, José M
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In this study is compared the state of science between countries whit similar GDP, such as Spain, Mexico and Indonesia. For accomplish this goal, SciVal is used to achieve a quantitative collection of specific data on the production of sci- entific research in the field of informatics within these countries. In the investigation, factors such as the number of publications, the generation of impact in citations and the collaboration that institutions and authors can carry out were considered. The study proposes to distinguish between productivity and the footprint generated by scientific research in informatics by comparing these three countries, emphasizing the importance of factors that go beyond GDP to promote scientific innovation. This research is specially centered in computer science along this three countries, {"references":["Callen, T. (2008). What is gross domestic product. Finance \\& Development, 45(4), 48-49.","Autenticación Bases de Datos Biblioteca TEC. (s/f). Scival.com. Retrieved on April 29, 2023, https://0.www.scival.com/home","Maradana, R. P., Pradhan, R. P., Dash, S., Gaurav, K., Jayakumar, M., \\& Chatterjee, D. (2017). Does innovation promote economic growth? Evidence from European countries. Journal of Innovation and Entrepreneurship, 6(1). doi:10.1186/s13731-016-0061-9","Ventosa‐Santaulària, D., Hernández‐Román, L. G., & Amezcua, A. V. (2021). Recessions and potential GDP: The case of Mexico. Bulletin of Economic Research, 73(2), 179-195.","World Bank Group - international development, poverty, & sustainability. (s/f). World Bank. Retrieved on April 29, 2023, https://www.worldbank.org/en/home","Samimi, A. J. (2011). Scientific output and GDP: Evidence from countries around the world. Journal of Education and Vocational Research, 2(2), 38-41.","Hill, H. (2000). The Indonesian Economy. Cambridge University Press.","Ferreira, V., Pié, L., & Terceño, A. (2021). Economic impact of the bioeconomy in Spain: Multiplier effects with a bio social accounting matrix. Journal of Cleaner Production, 298, 126752.","Thornton, C. (2021). Revolution in development: Mexico and the governance of the global economy. University of California Press."]}
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- 2023
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14. CORRECCIÓN DE RUIDO TEMPORAL Y ESPACIAL ORIENTADO A LA MAXIMIZACIÓN DE CONTRASTE Y COMPENSACIÓN DE ILUMINACIÓN EN IMÁGENES INFRARROJAS
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Alejandro Jaramillo-I, Ramiro Arango, and José Bestier Padilla-B
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H1-99 ,Vignetting ,Mean squared error ,Pixel ,Rank (linear algebra) ,Defectos del Hardware ,Defectos del Medio ,media_common.quotation_subject ,General Medicine ,Maximización de Contraste ,Mathematical morphology ,General Works ,Estadísticas Constantes ,Social sciences (General) ,Noise ,T1-995 ,Contrast (vision) ,Rango Constante ,Infrarrojo ,Constant (mathematics) ,Algorithm ,Technology (General) ,media_common ,Mathematics - Abstract
Las imágenes infrarrojas presentan defectos asociados al hardware, como son: píxeles defectuosos, ruido temporal, ruido espacial, vignetting entre otros; e inherentes al medio como cambios de iluminación, corrientes de convección y conducción. En este trabajo se hace uso de metodologías enfocadas en la corrección de no uniformidades como lo es el algoritmo de las estadísticas constantes (CS) y rango constante (CR), así mismo se utiliza la morfología matemática y mapeos de contraste (MC) con el objetivo de maximizar el contraste y compensar los cambios de iluminación de cada uno de los frames infrarrojos. Las métricas utilizadas para evaluar el desempeño de las técnicas corresponden al RMSE (error cuadrático medio) y al índice de merito Rho el cual es un estimativo de la cantidad de ruido eliminado, los resultados obtenidos con la utilización de las técnicas de corrección de no uniformidades presentan un índice de merito Rho y un RMSE bajo en comparación a los valores de estas métricas para frames contaminados, siendo estos cercanos a valores de las métricas obtenidos para un frame sin ruido espacial, aun, mejores resultados se obtienen cuando se aplican los operadores morfológicos y mapeos de contraste a las secuencias de imágenes provenientes de la etapa de corrección de ruido, dado que el contraste de la imagen es mejorado adaptativamente.
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- 2021
15. Epidemiology and predictive factors for early and late mortality in Candida bloodstream infections: a population-based surveillance in Spain
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Puig-Asensio, M., Padilla, B., Garnacho-Montero, J., Zaragoza, O., Aguado, J.M., Zaragoza, R., Montejo, M., Muñoz, P., Ruiz-Camps, I., Cuenca-Estrella, M., and Almirante, B.
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- 2014
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16. Lack of association between genotypes and haematogenous seeding infections in a large cohort of patients with methicillin-resistant Staphylococcus aureus bacteraemia from 21 Spanish hospitals
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Gasch, O., Camoez, M., Dominguez, M.A., Padilla, B., Pintado, V., Almirante, B., Martín-Gandul, C., López-Medrano, F., de Gopegui, E. Ruiz, Ramón Blanco, J., García-Pardo, G., Calbo, E., Horcajada, J.P., Granados, A., Jover-Sáenz, A., Dueñas, C., and Pujol, M.
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- 2014
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17. Response
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Montejo, Leigh, Richesson, Rachel, Padilla, B. Iris, Zychowicz, Michael E., and Hambley, Crystal
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- 2018
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18. SISTEMAS OPEN HARDWARE Y OPEN SOURCE APLICADOS A LA ENSEÑANZA DE LA ELECTRÓNICA
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Ramiro Arango, Álvaro Andrés Navarro, and José Bestier Padilla B.
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open source ,open hardware ,sistemas microcontrolados ,Technology (General) ,T1-995 ,General Works ,Social sciences (General) ,H1-99 - Abstract
Los sistemas open source y open hardware son una opción económica, eficiente y flexible para implementar y desarrollar tecnología en el aula. El uso de estas herramientas permite la construcción de sistemas complejos haciendo uso de software y hardware diseñado por terceros, ofreciendo un gran flexibilidad gracias a la disponibilidad del código y circuitos esquemáticos; de esta manera se logra ajustar el comportamiento de las aplicaciones obteniendo algunos beneficios como: reducción de tiempo de desarrollo, expansión de aplicaciones, modularidad y corrección de problemas de una manera práctica. Adicionalmente, estos sistemas son de extrema utilidad para el caso en el cual sea necesario reducir costos, muy común en ambientes educativos de nuestra región que cuentan con recursos muy limitados. La calidad de las herramientas para el desarrollo de las aplicaciones es muy buena y no tienen nada que envidiarle a equivalentes comerciales. Con estas aplicaciones se pretende también involucrar a los estudiantes en proyectos a nivel de trabajos de fin de materia y/o proyectos de grado en la cultura del open Source tanto de software como de Hardware. Particularmente, en el GIDET se ha venido desarrollando aplicaciones con microcontroladores PIC’s y ATMEL, para robótica y otras áreas apoyados en el IDEA (Integrated Development Enviroment for coding Algorithms), un software de ambiente gráfico desarrollado en la región, el cual permite la construcción de programas a partir de algoritmos diseñados en diagramas de flujo y/o lenguajes de alto nivel (C, C++), con el IDEA además de diseñar la aplicación al finalizar es posible descargar el programa ejecutable en sistemas basados en microcontroladores. Los sistemas con los que se han realizado las aplicaciones open hardware utilizan el mismo sistema de conexión de los módulos arduino, lo que permite la conexión simultánea de varias tarjetas para la construcción de prototipos con cierta complejidad. Por su diseño basado en arduino, se puedan utilizar con ellos los módulos que ofrecen otras empresas que utilizan la misma tecnología. Los módulos son de arquitectura abierta. En el IDEA es posible contar simultáneamente con las rutinas y planos del hardware requeridos para la construcción de la aplicación. A partir de proyectos de investigación y de aula se vienen desarrollando aplicaciones con tecnologías inalámbricas basados igualmente en sistemas open hardware.
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- 2014
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19. 290 Risankizumab (RZB) for active psoriatic arthritis (PsA): Integrated subgroup analysis from 2 double-blind, placebo-controlled, phase 3 studies (KEEPsAKE 1 and KEEPsAKE 2)
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Merola, J., primary, Duffin, K., additional, Padilla, B., additional, Xue, Z., additional, Photowala, H., additional, Kaplan, B., additional, and McInnes, I., additional
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- 2022
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20. MANIPULACIÓN INALÁMBRICA DE UN BRAZO ROBÓTICO POR MEDIO DEL KINECT
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Diego Andrés Garzón Villa, José Bestier Padilla B, and Jesús David Cardona Cuesta
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kinect ,brazo robótico ,reconocimiento de movimientos ,transmisión inalámbrica ,Technology (General) ,T1-995 ,General Works ,Social sciences (General) ,H1-99 - Abstract
La implementación de robots ha permitido desde años atrás mejorar la calidad de vida del ser humano mediante su reemplazo en actividades que requieren ser repetitivas o que presentan altos grados de dificultad. El presente trabajo consiste en direccionar un brazo robótico cuyas funciones se generarán y transmitirán desde un ordenador vía inalámbrica, el robot empleado se encuentra dentro de la clasificación de robots móviles manipuladores. Para generar el direccionamiento del brazo se utiliza el Kinect como dispositivo de reconocimiento de movimientos; una vez realizado el procesamiento adecuado de la información captada, se transmiten los datos de forma inalámbrica utilizando la tecnología Zigbee hacia el brazo robótico, compuesto por un sistema de recepción y un circuito microcontrolado que permite manipularlo.
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- 2013
21. Predictive factors for mortality in patients with methicillin-resistant Staphylococcus aureus bloodstream infection: impact on outcome of host, microorganism and therapy
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Gasch, O., Camoez, M., Dominguez, M.A., Padilla, B., Pintado, V., Almirante, B., Molina, J., Lopez-Medrano, F., Ruiz, E., Martinez, J.A., Bereciartua, E., Rodriguez-Lopez, F., Fernandez-Mazarrasa, C., Goenaga, M.A., Benito, N., Rodriguez-Baño, J., Espejo, E., and Pujol, M.
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- 2013
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22. Healthcare-associated, community-acquired and hospital-acquired bacteraemic urinary tract infections in hospitalized patients: a prospective multicentre cohort study in the era of antimicrobial resistance
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Horcajada, J.P., Shaw, E., Padilla, B., Pintado, V., Calbo, E., Benito, N., Gamallo, R., Gozalo, M., and Rodríguez-Baño, J.
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- 2013
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23. Human immunodeficiency virus continuum of care in 11 european union countries at the end of 2016 overall and by key population: Have we made progress?
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Vourli, G, Noori, T, Pharris, A, Porter, K, Axelsson, M, Begovac, J, Cazein, F, Costagliola, D, Cowan, S, Croxford, S, Monforte, A, Delpech, V, Diaz, A, Girardi, E, Gunsenheimer-Bartmeyer, B, Hernando, V, Leierer, G, Lot, F, Nunez, O, Obel, N, Op de Coul, E, Paraskeva, D, Patrinos, S, Reiss, P, Schmid, D, Sonnerborg, A, Suligoi, B, Supervie, V, van Sighem, A, Zangerle, R, Touloumi, G, Egle, A, Kanatschnig, M, Ollinger, A, Rieger, A, Schmied, B, Wallner, E, Dewasurendra, D, Gisinger, M, Kitchen, M, Plattner, A, Rieser, E, Sarcletti, M, Greil, R, Schachner, M, Skocic, M, Muller, M, Aichwalder, R, Chromy, D, Grabmeier-Pfstershammer, K, Skoll, M, Touzeau, V, Cichon, P, Wolf-Nussmuller, S, Laferl, H, Zoufaly, A, Genger-Hackl, C, Kapper, A, Schneeberger, T, Trattner, E, Schober, G, Atzl, M, Hartmann, B, Puchhammer-Stockl, E, Berg, J, Appoyer, H, Rappold, M, Strickner, S, Schindelwig, K, Ledergerber, B, Fatkenheuer, G, Gerstof, J, Kronborg, G, Pedersen, C, Larsen, C, Pedersen, G, Mohey, R, Nielsen, L, Weise, L, Kvinesdal, B, Jensen, J, Abgrall, S, Bernard, L, Billaud, E, Boue, F, Boyer, L, Cabie, A, Caby, F, Canestri, A, Cotte, L, de Truchis, P, Duval, X, Duvivier, C, Enel, P, Fischer, H, Gasnault, J, Gaud, C, Grabar, S, Khuong-Josses, M, Launay, O, Marchand, L, Mary-Krause, M, Matheron, S, Melica-Gregoire, G, Melliez, H, Meynard, J, Nacher, M, Pavie, J, Piroth, L, Poizot-Martin, I, Pradier, C, Reynes, J, Rouveix, E, Simon, A, Slama, L, Tattevin, P, Tissot-Dupont, H, Biga, J, Kurth, T, Jacquemet, N, Guiguet, M, Leclercq, S, Lievre, L, Marshall, E, Roul, H, Selinger-Leneman, H, Potard, V, Benveniste, O, Breton, G, Lupin, C, Bourzam, E, Girard, P, Fonquernie, L, Valin, N, Lefebvre, B, Sebire, M, Pialoux, G, Lebrette, M, Tibaut, P, Adda, A, Hamidi, M, Cadranel, J, Lavole, A, Parrot, A, Bouchaud, O, Vignier, N, Mechai, F, Makhlouf, S, Honore, P, Bergmann, J, Delcey, V, Lopes, A, Sellier, P, Parrinello, M, Oksenhendler, E, Gerard, L, Molina, J, Rozenbaum, W, Denis, B, De Castro, N, Lascoux, C, Yazdanpanah, Y, Lariven, S, Joly, V, Rioux, C, Poupard, M, Taverne, B, Sutton, L, Masse, V, Genet, P, Wifaq, B, Gerbe, J, Grefe, S, Dupont, C, Freire Maresca, A, Reimann, E, Bloch, M, Meier, F, Mortier, E, Zeng, F, Montoya, B, Perronne, C, Mathez, D, Marigot-Outtandy, D, Berthe, H, Greder Belan, A, Terby, A, Godin Collet, C, Marque Juillet, S, Ruquet, M, Roussin-Bretagne, S, Colardelle, P, Granier, F, Laurichesse, J, Perronne, V, Akpan, T, Marcou, M, Daneluzzi, V, Veyssier-Belot, C, Masson, H, Welker, Y, Brazille, P, Kahn, J, Zucman, D, Majerholc, C, Fourn, E, Bornarel, D, Chambrin, V, Kansau, I, Raho-Moussa, M, Lelievre, J, Saidani, M, Chesnel, C, Dumont, C, Vittecoq, D, Derradji, O, Bolliot, C, Goujard, C, Teicher, E, Mole, M, Bourdic, K, Salmon, D, Le Jeunne, C, Guet, P, Pietri, M, Pannier Metzger, E, Marcou, V, Loulergue, P, Dupin, N, Morini, J, Deleuze, J, Gerhardt, P, Chanal, J, Weiss, L, Lucas, M, Jung, C, Ptak, M, Viard, J, Ghosn, J, Gazalet, P, Cros, A, Maignan, A, Lortholary, O, Rouzaud, C, Touam, F, Benhadj, K, Consigny, P, Bossi, P, Gergely, A, Cessot, G, Durand, F, Beck-Wirth, G, Michel, C, Benomar, M, Rey, D, Partisani, M, Cheneau, C, Batard, M, Fischer, P, Leclercq, P, Blanc, M, Morand, P, Epaulard, O, Signori-Schmuck, A, Laurichesse, H, Jacomet, C, Vidal, M, Coban, D, Casanova, S, Fresard, A, Guglielminotti, C, Botelho-Nevers, E, Brunon-Gagneux, A, Ronat, V, Verdon, R, Dargere, S, Haustraete, E, Feret, P, Goubin, P, Chavanet, P, Fillion, A, Croisier, D, Gohier, S, Arvieux, C, Souala, F, Chapplain, J, Ratajczak, M, Rohan, J, Faller, J, Ruyer, O, Gendrin, V, Toko, L, Chirouze, C, Hustache-Mathieu, L, Faucher, J, Proust, A, Magy-Bertrand, N, Gil, H, Meaux-Ruault, N, Sotto, A, Rouanet, I, Mauboussin, J, Doncesco, R, Jacques, G, May, T, Rabaud, C, Andre, M, Delestan, M, Bouillon, M, Bani-Sadr, F, Rouger, C, Berger, J, Nguyen, Y, Marchou, B, Delobel, P, Martin Blondel, G, Cuzin, L, Biezunski, N, Alric, L, Bonnet, D, Guivarch, M, Palacin, A, Payssan, V, Ajana, F, Meybeck, A, Viget, N, Pugliese, P, Roger, P, Rosenthal, E, Durant, J, Cua, E, Naqvi, A, Perbost, I, Risso, K, Quinsat, D, Raphael, S, Del Giudice, P, Dides, P, Sambuc, R, Antolini-Bouvenot, M, Druart, P, Meddeb, L, Ravaux, I, Menard, A, Tomei, C, Dhiver, C, Moreau, J, Mokhtari, S, Soavi, M, Tomas, V, Bregigeon, S, Faucher, O, Obry-Roguet, V, Ritleng, A, Petit, N, Bartoli, C, Ruiz, J, Blanc, D, Allegre, T, Sordage, M, Riou, J, Faudon, C, Slama, B, Zerazhi, H, Boulat, O, Chebrek, S, Beyrne, M, Granet Brunello, P, Pellissier, L, Bonnabel, D, Cohen Valensi, R, Mouchet, B, Mboungou, G, Lafeuillade, A, Hope-Rapp, E, Hittinger, G, Philip, G, Lambry, V, Raf, F, Allavena, C, Hall, N, Reliquet, V, Chidiac, C, Ferry, T, Perpoint, T, Miailhes, P, Boibieux, A, Livrozet, J, Makhlouf, D, Brunel, F, Chiarello, P, Hoen, B, Lamaury, I, Fabre, I, Samar, K, Duvallon, E, Clavel, C, Stegmann, S, Walter, V, Adriouch, L, Huber, F, Vanticlke, V, Couppie, P, Abel, S, Pierre-Francois, S, Ricaud, C, Rodet, R, Wartel, G, Sautron, C, Poubeau, P, Borgherini, G, Camuset, G, Arasteh, K, Kowohl Vivantes, S, Schurmann, D, Warncke Charite, M, Rockstroh, J, Wasmuth, J, Hass, S, Jensen, B, Feind, C, Esser, S, Schenk-Westkamp, P, Haberl, A, Stephan, C, Plettenberg, A, Kuhlendahl, F, Adam, A, Weitner, L, Schewe, K, Goey, H, Fenske, S, Buhk, T, Stellbrink, H, Hofmann, C, Hansen, S, Degen, O, Heuer, M, Stoll, M, Gerschmann, S, Horst, H, Trautmann, S, Gillor, D, Bogner, J, Sonntag, B, Salzberger, B, Fritzsche, C, Adamis, G, Antoniadou, A, Chini, M, Chrysos, G, Gikas, A, Gogos, H, Katsarou, O, Lazanas, M, Metallidis, S, Panagopoulos, P, Paparizos, V, Papastamopoulos, V, Paraskevis, D, Psychogiou, M, Sambatakou, H, Sipsas, N, Pantazis, N, Papadopoulos, A, Nitsotolis, T, Xylomenos, G, Marangos, M, Kouramba, A, Kontos, A, Lioni, A, Tsachouridou, O, Kourkounti, S, Ganitis, A, Barbounakis, E, d'Arminio Monforte, A, Antinori, A, Andreoni, M, Castagna, A, Castelli, F, 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M., van den Berg-Cameron H. J., de Groot J., Boucher C. A. B., Koopmans M. P. G., van Kampen J. J. A., Fraaij P. L. A., van Rossum A. M. C., Vermont C. L., van der Knaap L. C., Visser E., Branger J., Douma R. A., Duijf-Van de Ven C. J. H. M., Schippers E. F., van Nieuwkoop C., van IJperen J. M., Geilings J., van der Hut G., van Burgel N. D., Leyten E. M. S., Gelinck L. B. S., Mollema F., Davids-Veldhuis S., Wildenbeest G. S., Heikens E., Groeneveld P. H. P., Bouwhuis J. W., Lammers A. J. J., Kraan S., van Hulzen A. G. W., Kruiper M. S. M., van der Bliek G. L., Bor P. C. J., Bloembergen P., Wolfagen M. J. H. M., Ruijs G. J. H. M., Kroon F. P., de Boer M. G. J., Scheper H., Jolink H., Dorama W., van Holten N., Claas E. C. J., Wessels E., den Hollander J. G., El Moussaoui R., Pogany K., Kastelijns M., Smit J. V., Smit E., Struik-Kalkman D., Tearno C., van Niekerk T., Pontesilli O., Lowe S. H., Oude Lashof A. M. L., Posthouwer D., Ackens R. P., Burgers K., Schippers J., Weijenberg-Maes B., van Loo I. H. M., Havenith T. R. A., Weijer S., van Vonderen M. G. A., Kampschreur L. M., Faber S., Steeman-Bouma R., Weel J., Kootstra G. J., Delsing C. E., van der Burg-Van de Plas M., Heins H., Kortmann W., van Twillert G., Renckens R., Ruiter-Pronk D., van Truijen-Oud F. A., Cohen Stuart J. W. T., Jansen E. R., Hoogewerf M., Rozemeijer W., van der Reijden W. A., Sinnige J. C., Brinkman K., van den Berk G. E. L., Blok W. L., Frissen P. H. J., Lettinga K. D., Schouten W. E. M., Veenstra J., Vrouenraets S. M. E., Brouwer C. J., Geerders G. F., Hoeksema K., Kleene M. J., Knapen M., van der Meche I. B., Mulder-Seeleman E., Toonen A. J. M., Wijnands S., Kwa D., van Crevel R., van Aerde K., Doferhof A. S. M., Henriet S. S. V., ter Hofstede H. J. M., Hoogerwerf J., Keuter M., Richel O., Albers M., Grintjes-Huisman K. J. T., de Haan M., Marneef M., Strik-Albers R., Rahamat-Langendoen J., Stelma F. F., Burger D., Gisolf E. H., Hassing R. J., Claassen M., ter Beest G., van Bentum P. H. M., Langebeek N., Tiemessen R., Swanink C. M. A., van Lelyveld S. F. L., Soetekouw R., van der Prijt L. M. M., van der Swaluw J., Bermon N., Jansen R., Herpers B. L., Veenendaal D., Verhagen D. W. M., Lauw F. N., van Broekhuizen M. C., van Wijk M., Bierman W. F. W., Bakker M., Kleinnijenhuis J., Kloeze E., Middel A., Scholvinck E. H., Stienstra Y., Verhage A. R., Wouthuyzen-Bakker K. M., Boonstra A., de Groot-De Jonge H., van der Meulen P. A., de Weerd D. A., Niesters H. G. M., van Leer-Buter C. C., Knoester M., Hoepelman A. I. M., Arends J. E., Barth R. E., Bruns A. H. W., Ellerbroek P. M., Mudrikova T., Oosterheert J. J., de Regt M. J. A., Schadd E. M., van Zoelen M. A. D., Aarsman K., Grifoen-Van Santen B. M. G., de Kroon I., van Rooijen C. S. A. M., van Berkel M., Schuurman R., Verduyn-Lunel F., Wensing A. M. J., Bont L. J., Geelen S. P. M., Loefen Y. G. T., Wolfs T. F. W., Nauta N., Zaheri S., Boyd A. C., Bezemer D. O., van Sighem A. I., Smit C., Hillebregt M., de Jong A., Woudstra T., Bergsma D., Meijering R., van de Sande L., Rutkens T., van der Vliet S., de Groot L., van den Akker M., Bakker Y., El Berkaoui A., Bezemer M., Bretin N., Djoechro E., Geerlinks J., Kruijne E., Lodewijk C., Lucas E., van der Meer R., Munjishvili L., Paling F., Peeck B., Ree C., Regtop R., Ruijs Y., Schoorl M., Schnorr P., Tuijn E., Veenenberg L., Witte E. C., Tuk B., Moreno S., del Amo J., Dalmau D., Navarro M. L., Gonzalez M. I., Blanco J. L., Garcia F., Rubio R., Iribarren J. A., Gutierrez F., Vidal F., Berenguer J., Gonzalez J., Sobrino P., Alejos B., Alvarez D., Jarrin I., Moreno C., Munoz-Fernandez M. A., Garcia-Merino I., Rico C. G., de la Fuente J. G., Torre A. G., Portilla J., Merino E., Reus S., Boix V., Giner L., Gadea C., Portilla I., Pampliega M., Diez M., Rodriguez J. C., Sanchez-Paya J., Podzamczer D., Imaz E. F. A., Van Den Eyncle E., Di Yacovo S., Sumoy M., Gomez J. L., Hernandez J., Aleman M. R., Alonso M. D. M., Hernandez M. I., Diaz-Flores F., Garcia D., Pelazas R., Asensi V., Valle E., Carton J. A., Perez V. E., Molina M. J. T., Garcia J. V., Carrera E. P. -C., Pulido F., Bisbal O., Matarranz M., Lagarde M., Rubio-Martin R., Hernando A., Bermejo L., Dominguez L., Arrizabalaga J., Aramburu M. J., Camino X., Rodriguez-Arrondo F., von Wichmann M. A., Tome L. P., Goenaga M. A., Bustinduy M. J., Galparsoro H. A., Ibarguren M., Aguado M., Umerez M., Masia M., Lopez C., Padilla S., Navarro A., Montolio F., Robledano C., Colome J. G., Adsuar A., Pascual R., Carlos F., Martinez M., Garcia J. L., Fernandez M., Garcia E., Muga R., Tor J., Sanvisens A., Bernaldo de Quiros Lopez J. C., Miralles P., Gutierrez I., Ramirez M., Padilla B., Gijon P., Carrero A., Aldamiz-Echevarria T., Tejerina F., Parras F. J., Balsalobre P., Diez C., Peraire J., Vilades C., Veloso S., Vargas M., Lopez-Dupla M., Olona M., Aguilar A., Sirvent J. J., Alba V., Calavia O., Montero M., Lacruz J., Blanes M., Calabuig E., Cuellar S., Lopez J., Salavert M., de la Serna I. B., Arribas J. R., Montes M. L., Pena J. M., Arribas B., Castro J. M., Zamora J., Perez I., Estebanez M., Garcia S., Diaz M., Alcariz N. S., Mingorance J., Montero D., Gonzalez A., Isabel de Jose M., de los Santos I., Sanz J., Salas A., Sarria C., Berrocal A. G., Garcia-Fraile L., Oteo J. A., Blanco J. R., Ibarra V., Metola L., Sanz M., Perez-Martinez L., Pascual A., Ramos C., Arazo P., Gil D., Jaen A., Cairo M., Irigoyen D., Jordano Q., Xercavins M., Martinez-Lacasa J., Velli P., Font R., Sanmarti M., Ibanez L., Rivero M., Casado M. I., Diaz J. A., Uriz J., Reparaz J., Irigoyen C., Arraiza M. J., Segura F., Amengual M. J., Navarro G., Sala M., Cervantes M., Pineda V., Segura V., Navarro M., Anton E., Nogueras M. M., Casado J. L., Dronda F., Moreno A., Elias M. J. P., Lopez D., Gutierrez C., Madrid N., Lamas A., Marti P., de Diaz A., Serrrano S., Donat L., Cano A., Bernal E., Munoz A., Pena A., Munoz L., Parra J., Alvarez M., Chueca N., Guillot V., Vinuesa D., Fernandez J. A., Del Romero J., Rodriguez C., Puerta T., Carrio J. C., Vera M., Ballesteros J., Domingo P., Sambeat M. A., Lamarca K., Mateo G., Gutierrez M., Fernandez I., Antela A., Losada E., Riera M., Penaranda M., Leyes M., Ribas M. A., Campins A. A., Vidal C., Gil L., Fanjul F., Marinescu C., Ribera E., Santos J., Marquez M., Viciana I., Palacios R., Gonzalez C. M., Viciana P., Leal M., Lopez-Cortes L. F., Espinosa N., Munoz J., Zubero M. Z., Baraia-Etxaburu J. M., Ibarra S., Ferrero O., Lopez de Munain J., Camara M. M., Lopez I., de la Pena M., Suarez-Garcia I., Malmierca E., Olalla J., del Arco A., de la Torre J., Prada J. L., Caracuel Z., Lopez-Lirola A. M., Lozano A. B., Fernandez E., Fernandez J. M., Martinez O. J., Vera F. J., Martinez L., Garcia J., Alcaraz B., Jimeno A., Poveda E., Pernas B., Mena A., Grandal M., Castro A., Pedreira J. D., Galera C., Albendin H., Iborra A., Campillo M. A., Vidal A., Amador C., Pasquau F., Ena J., Benito C., Fenoll V., Mohamed-Balghata M. O., Gomez M. A., Alberto de Zarraga M., Rivas M. E., Gorgolas M., Svedhem-Johansson V., Flamholc L., Gisslen M., Hejdeman B., Norgren H., and Wendahl S.
- Abstract
Background. High uptake of antiretroviral treatment (ART) is essential to reduce human immunodeficiency virus (HIV) transmission and related mortality; however, gaps in care exist. We aimed to construct the continuum of HIV care (CoC) in 2016 in 11 European Union (EU) countries, overall and by key population and sex. To estimate progress toward the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 target, we compared 2016 to 2013 estimates for the same countries, representing 73% of the population in the region. Methods. A CoC with the following 4 stages was constructed: number of people living with HIV (PLHIV); proportion of PLHIV diagnosed; proportion of those diagnosed who ever initiated ART; and proportion of those ever treated who achieved viral suppression at their last visit. Results. We estimated that 87% of PLHIV were diagnosed; 92% of those diagnosed had ever initiated ART; and 91% of those ever on ART, or 73% of all PLHIV, were virally suppressed. Corresponding figures for men having sex with men were: 86%, 93%, 93%, 74%; for people who inject drugs: 94%, 88%, 85%, 70%; and for heterosexuals: 86%, 92%, 91%, 72%. The proportion suppressed of all PLHIV ranged from 59% to 86% across countries. Conclusions. The EU is close to the 90-90-90 target and achieved the UNAIDS target of 73% of all PLHIV virally suppressed, significant progress since 2013 when 60% of all PLHIV were virally suppressed. Strengthening of testing programs and treatment support, along with prevention interventions, are needed to achieve HIV epidemic control.
- Published
- 2020
24. Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?
- Author
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Vourli, G., Noori, T., Pharris, A., Porter, K., Axelsson, M., Begovac, J., Cazein, F., Costagliola, D., Cowan, S., Croxford, S., Monforte, A. D., Delpech, V., Diaz, A., Girardi, E., Gunsenheimer-Bartmeyer, B., Hernando, V., Leierer, G., Lot, F., Nunez, O., Obel, N., Op de Coul, E., Paraskeva, D., Patrinos, S., Reiss, P., Schmid, D., Sonnerborg, A., Suligoi, B., Supervie, V., van Sighem, A., Zangerle, R., Touloumi, G., Egle, A., Kanatschnig, M., Ollinger, A., Rieger, A., Schmied, B., Wallner, E., Dewasurendra, D., Gisinger, M., Kitchen, M., Plattner, A., Rieser, E., Sarcletti, M., Greil, R., Schachner, M., Skocic, M., Muller, M., Aichwalder, R., Chromy, D., Grabmeier-Pfstershammer, K., Skoll, M., Touzeau, V., Cichon, P., Wolf-Nussmuller, S., Laferl, H., Zoufaly, A., Genger-Hackl, C., Kapper, A., Schneeberger, T., Trattner, E., Schober, G., Atzl, M., Hartmann, B., Puchhammer-Stockl, E., Berg, J., Appoyer, H., Rappold, M., Strickner, S., Schindelwig, K., Ledergerber, B., Fatkenheuer, G., Gerstof, J., Kronborg, G., Pedersen, C., Larsen, C. S., Pedersen, G., Mohey, R., Nielsen, L., Weise, L., Kvinesdal, B., Jensen, J., Abgrall, S., Bernard, L., Billaud, E., Boue, F., Boyer, L., Cabie, A., Caby, F., Canestri, A., Cotte, L., de Truchis, P., Duval, X., Duvivier, C., Enel, P., Fischer, H., Gasnault, J., Gaud, C., Grabar, S., Khuong-Josses, M. A., Launay, O., Marchand, L., Mary-Krause, M., Matheron, S., Melica-Gregoire, G., Melliez, H., Meynard, J. L., Nacher, M., Pavie, J., Piroth, L., Poizot-Martin, I., Pradier, C., Reynes, J., Rouveix, E., Simon, A., Slama, L., Tattevin, P., Tissot-Dupont, H., Biga, J., Kurth, T., Jacquemet, N., Guiguet, M., Leclercq, S., Lievre, L., Marshall, E., Roul, H., Selinger-Leneman, H., Potard, V., Benveniste, O., Breton, G., Lupin, C., Bourzam, E., Girard, P. M., Fonquernie, L., Valin, N., Lefebvre, B., Sebire, M., Pialoux, G., Lebrette, M. G., Tibaut, P., Adda, A., Hamidi, M., Cadranel, J., Lavole, A., Parrot, A., Bouchaud, O., Vignier, N., Mechai, F., Makhlouf, S., Honore, P., Bergmann, J. 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D., Saidani, M., Chesnel, C., Dumont, C., Vittecoq, D., Derradji, O., Bolliot, C., Goujard, C., Teicher, E., Mole, M., Bourdic, K., Salmon, D., Le Jeunne, C., Guet, P., Pietri, M. P., Pannier Metzger, E., Marcou, V., Loulergue, P., Dupin, N., Morini, J. P., Deleuze, J., Gerhardt, P., Chanal, J., Weiss, L., Lucas, M. L., Jung, C., Ptak, M., Viard, J. P., Ghosn, J., Gazalet, P., Cros, A., Maignan, A., Lortholary, O., Rouzaud, C., Touam, F., Benhadj, K., Consigny, P. H., Bossi, P., Gergely, A., Cessot, G., Durand, F., Beck-Wirth, G., Michel, C., Benomar, M., Rey, D., Partisani, M., Cheneau, C., Batard, M. 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A., Katsarou, O., Lazanas, M., Metallidis, S., Panagopoulos, P., Paparizos, V., Papastamopoulos, V., Paraskevis, D., Psychogiou, M., Sambatakou, H., Sipsas, N. V., Pantazis, N., Papadopoulos, A., Nitsotolis, T., Xylomenos, G., Marangos, M. N., Kouramba, A., Kontos, A., Lioni, A., Tsachouridou, O., Kourkounti, S., Ganitis, A., Barbounakis, E., d'Arminio Monforte, A., Antinori, A., Andreoni, M., Castagna, A., Castelli, F., Cauda, R., Di Perri, G., Galli, M., Iardino, R., Ippolito, G., Lazzarin, A., Marchetti, G. C., Rezza, G., von Schloesser, F., Viale, P., Ceccherini-Silberstein, F., Cozzi-Lepri, A., Lo Caputo, S., Mussini, C., Puoti, M., Perno, C. F., Bai, F., Balotta, C., Bandera, A., Bonora, S., Borderi, M., Calcagno, A., Capetti, A., Capobianchi, M. 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Psychogiou M., Sambatakou H., Sipsas N.V., Pantazis N., Papadopoulos A., Nitsotolis T., Xylomenos G., Marangos M.N., Kouramba A., Kontos A., Lioni A., Tsachouridou O., Kourkounti S., Ganitis A., Barbounakis E., d'Arminio Monforte A., Antinori A., Andreoni M., Castagna A., Castelli F., Cauda R., Di Perri G., Galli M., Iardino R., Ippolito G., Lazzarin A., Marchetti G.C., Rezza G., von Schloesser F., Viale P., Ceccherini-Silberstein F., Cozzi-Lepri A., Lo Caputo S., Mussini C., Puoti M., Perno C.F., Bai F., Balotta C., Bandera A., Bonora S., Borderi M., Calcagno A., Capetti A., Capobianchi M.R., Cicalini S., Cingolani A., Cinque P., Di Biagio A., Gianotti N., Gori A., Guaraldi G., Lapadula G., Lichtner M., Madeddu G., Maggiolo F., Marchetti G., Monno L., Nozza S., Pinnetti C., Quiros Roldan E., Rossotti R., Rusconi S., Santoro M.M., Saracino A., Sarmati L., Fanti I., Galli L., Lorenzini P., Rodano A., Macchia M., Tavelli A., Carletti F., Carrara S., Di Caro A., Graziano S., Petroni F., Prota G., Trufa S., Giacometti A., Costantini A., Barocci V., Angarano G., Milano E., Suardi C., Donati V., Verucchi G., Castelnuovo F., Minardi C., Menzaghi B., Abeli C., Cacopardo B., Celesia B., Vecchiet J., Falasca K., Pan A., Lorenzotti S., Sighinolf L., Segala D., Blanc P., Vichi F., Cassola G., Viscoli C., Alessandrini A., Bobbio N., Mazzarello G., Fondaco L., Bonfanti P., Molteni C., Chiodera A., Milini P., Nunnari G., Pellicano G., Rizzardini G., Cannizzo E.S., Moioli M.C., Piolini R., Bernacchia D., Salpietro S., Tincati C., Puzzolante C., Migliorino C., Sangiovanni V., Borgia G., Esposito V., Di Flumeri G., Gentile I., Rizzo V., Cattelan A.M., Marinello S., Cascio A., Trizzino M., Francisci D., Schiaroli E., Parruti G., Sozio F., Magnani G., Ursitti M.A., Cristaudo A., Vullo V., Acinapura R., Moschese D., Capozzi M., Mondi A., Rivano Capparuccia M., Iaiani G., Latini A., Gagliardini R., Plazzi M.M., De Girolamo G., Vergori A., Cecchetto M., Viviani F., De Vito A., Rossetti B., Montagnani F., Franco A., Fontana Del Vecchio R., Di Giuli C., Caramello P., Orofno G.C., Sciandra M., Bassetti M., Londero A., Manfrin V., Battagin G., Starnini G., Ialungo A., van der Valk M., Geerlings S.E., Goorhuis A., Hovius J.W., Lempkes B., Nellen F.J.B., van der Poll T., Prins J.M., van Vugt M., Wiersinga W.J., Wit F.W.M.N., van Duinen M., van Eden J., Hazenberg A., van Hes A.M.H., Pijnappel F.J.J., Smalhout S.Y., Weijsenfeld A.M., Jurriaans S., Back N.K.T., Zaaijer H.L., Berkhout B., Cornelissen M.T.E., Schinkel C.J., Wolthers K.C., Peters E.J.G., van Agtmael M.A., Bomers M., Sigalof K.C.E., Heitmuller M., Laan L.M., Ang C.W., van Houdt R., Jonges M., van Prehn J., Kuijpers T.W., Pajkrt D., Scherpbier H.J., de Boer C., van der Plas A., van den Berge M., Stegeman A., Baas S., Hage de Loof L., Wintermans B., Veenemans J., Pronk M.J.H., Ammerlaan H.S.M., de Munnik E.S., Jansz A.R., Tjhie J., Wegdam M.C.A., Deiman B., Scharnhorst V., van Eeden A., Brokking W., Elsenburg L.J.M., Nobel H., Damen M., van Kasteren M.E.E., Berrevoets M.A.H., Brouwer A.E., Adams A., de Kruijf-Van de Wiel B.A.F.M., Keelan-Pfaf S., van der Ven B., Buiting A.G.M., Murck J.L., Versteeg D., de Vries-Sluijs T.E.M.S., Bax H.I., van Gorp E.C.M., Nouwen J.L., Rijnders B.J.A., Schurink C.A.M., Verbon A., de Jong-Peltenburg N.C., Bassant N., van Beek J.E.A., Vriesde M., van Zonneveld L.M., van den Berg-Cameron H.J., de Groot J., Boucher C.A.B., Koopmans M.P.G., van Kampen J.J.A., Fraaij P.L.A., van Rossum A.M.C., Vermont C.L., van der Knaap L.C., Visser E., Branger J., Douma R.A., Duijf-Van de Ven C.J.H.M., Schippers E.F., van Nieuwkoop C., van IJperen J.M., Geilings J., van der Hut G., van Burgel N.D., Leyten E.M.S., Gelinck L.B.S., Mollema F., Davids-Veldhuis S., Wildenbeest G.S., Heikens E., Groeneveld P.H.P., Bouwhuis J.W., Lammers A.J.J., Kraan S., van Hulzen A.G.W., Kruiper M.S.M., van der Bliek G.L., Bor P.C.J., Bloembergen P., Wolfagen M.J.H.M., Ruijs G.J.H.M., Kroon F.P., de Boer M.G.J., Scheper H., Jolink H., Dorama W., van Holten N., Claas E.C.J., Wessels E., den Hollander J.G., El Moussaoui R., Pogany K., Kastelijns M., Smit J.V., Smit E., Struik-Kalkman D., Tearno C., van Niekerk T., Pontesilli O., Lowe S.H., Oude Lashof A.M.L., Posthouwer D., Ackens R.P., Burgers K., Schippers J., Weijenberg-Maes B., van Loo I.H.M., Havenith T.R.A., Weijer S., van Vonderen M.G.A., Kampschreur L.M., Faber S., Steeman-Bouma R., Weel J., Kootstra G.J., Delsing C.E., van der Burg-Van de Plas M., Heins H., Kortmann W., van Twillert G., Renckens R., Ruiter-Pronk D., van Truijen-Oud F.A., Cohen Stuart J.W.T., Jansen E.R., Hoogewerf M., Rozemeijer W., van der Reijden W.A., Sinnige J.C., Brinkman K., van den Berk G.E.L., Blok W.L., Frissen P.H.J., Lettinga K.D., Schouten W.E.M., Veenstra J., Vrouenraets S.M.E., Brouwer C.J., Geerders G.F., Hoeksema K., Kleene M.J., Knapen M., van der Meche I.B., Mulder-Seeleman E., Toonen A.J.M., Wijnands S., Kwa D., van Crevel R., van Aerde 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Vilades C., Veloso S., Vargas M., Lopez-Dupla M., Olona M., Aguilar A., Sirvent J.J., Alba V., Calavia O., Montero M., Lacruz J., Blanes M., Calabuig E., Cuellar S., Lopez J., Salavert M., de la Serna I.B., Arribas J.R., Montes M.L., Pena J.M., Arribas B., Castro J.M., Zamora J., Perez I., Estebanez M., Garcia S., Diaz M., Alcariz N.S., Mingorance J., Montero D., Gonzalez A., Isabel de Jose M., de los Santos I., Sanz J., Salas A., Sarria C., Berrocal A.G., Garcia-Fraile L., Oteo J.A., Blanco J.R., Ibarra V., Metola L., Sanz M., Perez-Martinez L., Pascual A., Ramos C., Arazo P., Gil D., Jaen A., Cairo M., Irigoyen D., Jordano Q., Xercavins M., Martinez-Lacasa J., Velli P., Font R., Sanmarti M., Ibanez L., Rivero M., Casado M.I., Diaz J.A., Uriz J., Reparaz J., Irigoyen C., Arraiza M.J., Segura F., Amengual M.J., Navarro G., Sala M., Cervantes M., Pineda V., Segura V., Navarro M., Anton E., Nogueras M.M., Casado J.L., Dronda F., Moreno A., Elias M.J.P., Lopez D., Gutierrez C., Madrid N., 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Pedreira J.D., Galera C., Albendin H., Iborra A., Campillo M.A., Vidal A., Amador C., Pasquau F., Ena J., Benito C., Fenoll V., Mohamed-Balghata M.O., Gomez M.A., Alberto de Zarraga M., Rivas M.E., Gorgolas M., Svedhem-Johansson V., Flamholc L., Gisslen M., Hejdeman B., Norgren H., Wendahl S., Global Health, Infectious diseases, AII - Infectious diseases, APH - Aging & Later Life, ANS - Neuroinfection & -inflammation, Internal medicine, Medical Microbiology and Infection Prevention, AMS - Rehabilitation & Development, VU University medical center, Amsterdam Gastroenterology Endocrinology Metabolism, Pediatric surgery, Neurology, Amsterdam Neuroscience - Neurodegeneration, Pulmonary medicine, Psychiatry, APH - Mental Health, Amsterdam Neuroscience - Complex Trait Genetics, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, Ethics, Law & Medical humanities, APH - Quality of Care, ACS - Pulmonary hypertension & thrombosis, Amsterdam Neuroscience - Neuroinfection & -inflammation, Amsterdam Reproduction & Development (AR&D), APH - Societal Participation & Health, Pediatrics, HAL-SU, Gestionnaire, National and Kapodistrian University of Athens (NKUA), University College of London [London] (UCL), Public Health Agency of Sweden, University of Zagreb, Santé publique France - French National Public Health Agency [Saint-Maurice, France], Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Statens Serum Institut [Copenhagen], Public Health England [London], Università degli Studi di Milano = University of Milan (UNIMI), Instituto de Salud Carlos III [Madrid] (ISC), Istituto Nazionale di Malattie Infettive 'Lazzaro Spallanzani' (INMI), Robert Koch Institute [Berlin] (RKI), Innsbruck Medical University = Medizinische Universität Innsbruck (IMU), University of Copenhagen = Københavns Universitet (UCPH), National Institute for Public Health and the Environment [Bilthoven] (RIVM), Hellenic Center for Disease Control and Prevention, Amsterdam UMC - Amsterdam University Medical Center, Austrian Agency for Health and Food Safety (AGES), Department of Infectious Diseases, Institution of Medicine, Karolinska University Hospital and Karolinska Institutet, Istituto Superiore di Sanita [Rome], Stichting HIV Monitoring [Amsterdam], Universiteit van Amsterdam (UvA), University of Athens Medical School [Athens], Vourli, G, Noori, T, Pharris, A, Porter, K, Axelsson, M, Begovac, J, Cazein, F, Costagliola, D, Cowan, S, Croxford, S, Monforte, A, Delpech, V, Diaz, A, Girardi, E, Gunsenheimer-Bartmeyer, B, Hernando, V, Leierer, G, Lot, F, Nunez, O, Obel, N, Op de Coul, E, Paraskeva, D, Patrinos, S, Reiss, P, Schmid, D, Sonnerborg, A, Suligoi, B, Supervie, V, van Sighem, A, Zangerle, R, Touloumi, G, Egle, A, Kanatschnig, M, Ollinger, A, Rieger, A, Schmied, B, Wallner, E, Dewasurendra, D, Gisinger, M, Kitchen, M, Plattner, A, Rieser, E, Sarcletti, M, Greil, R, Schachner, M, Skocic, M, Muller, M, Aichwalder, R, Chromy, D, Grabmeier-Pfstershammer, K, Skoll, M, Touzeau, V, Cichon, P, Wolf-Nussmuller, S, Laferl, H, Zoufaly, A, Genger-Hackl, C, Kapper, A, Schneeberger, T, Trattner, E, Schober, G, Atzl, M, Hartmann, B, Puchhammer-Stockl, E, Berg, J, Appoyer, H, Rappold, M, Strickner, S, Schindelwig, K, Ledergerber, B, Fatkenheuer, G, Gerstof, J, Kronborg, G, Pedersen, C, Larsen, C, Pedersen, G, Mohey, R, Nielsen, L, Weise, L, Kvinesdal, B, Jensen, J, Abgrall, S, Bernard, L, Billaud, E, Boue, F, Boyer, L, Cabie, A, Caby, F, Canestri, A, Cotte, L, de Truchis, P, Duval, X, Duvivier, C, Enel, P, Fischer, H, Gasnault, J, Gaud, C, Grabar, S, Khuong-Josses, M, Launay, O, Marchand, L, Mary-Krause, M, Matheron, S, Melica-Gregoire, G, Melliez, H, Meynard, J, Nacher, M, Pavie, J, Piroth, L, Poizot-Martin, I, Pradier, C, Reynes, J, Rouveix, E, Simon, A, Slama, L, Tattevin, P, Tissot-Dupont, H, Biga, J, Kurth, T, Jacquemet, N, Guiguet, M, Leclercq, S, Lievre, L, Marshall, E, Roul, H, Selinger-Leneman, H, Potard, V, Benveniste, O, Breton, G, Lupin, C, Bourzam, E, Girard, P, Fonquernie, L, Valin, N, Lefebvre, B, Sebire, M, Pialoux, G, Lebrette, M, Tibaut, P, Adda, A, Hamidi, M, Cadranel, J, Lavole, A, Parrot, A, Bouchaud, O, Vignier, N, Mechai, F, Makhlouf, S, Honore, P, Bergmann, J, Delcey, V, Lopes, A, Sellier, P, Parrinello, M, Oksenhendler, E, Gerard, L, Molina, J, Rozenbaum, W, Denis, B, De Castro, N, Lascoux, C, Yazdanpanah, Y, Lariven, S, Joly, V, Rioux, C, Poupard, M, Taverne, B, Sutton, L, Masse, V, Genet, P, Wifaq, B, Gerbe, J, Grefe, S, Dupont, C, Freire Maresca, A, Reimann, E, Bloch, M, Meier, F, Mortier, E, Zeng, F, Montoya, B, Perronne, C, Mathez, D, Marigot-Outtandy, D, Berthe, H, Greder Belan, A, Terby, A, Godin Collet, C, Marque Juillet, S, Ruquet, M, Roussin-Bretagne, S, Colardelle, P, Granier, F, Laurichesse, J, Perronne, V, Akpan, T, Marcou, M, Daneluzzi, V, Veyssier-Belot, C, Masson, H, Welker, Y, 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Arvieux, C, Souala, F, Chapplain, J, Ratajczak, M, Rohan, J, Faller, J, Ruyer, O, Gendrin, V, Toko, L, Chirouze, C, Hustache-Mathieu, L, Faucher, J, Proust, A, Magy-Bertrand, N, Gil, H, Meaux-Ruault, N, Sotto, A, Rouanet, I, Mauboussin, J, Doncesco, R, Jacques, G, May, T, Rabaud, C, Andre, M, Delestan, M, Bouillon, M, Bani-Sadr, F, Rouger, C, Berger, J, Nguyen, Y, Marchou, B, Delobel, P, Martin Blondel, G, Cuzin, L, Biezunski, N, Alric, L, Bonnet, D, Guivarch, M, Palacin, A, Payssan, V, Ajana, F, Meybeck, A, Viget, N, Pugliese, P, Roger, P, Rosenthal, E, Durant, J, Cua, E, Naqvi, A, Perbost, I, Risso, K, Quinsat, D, Raphael, S, Del Giudice, P, Dides, P, Sambuc, R, Antolini-Bouvenot, M, Druart, P, Meddeb, L, Ravaux, I, Menard, A, Tomei, C, Dhiver, C, Moreau, J, Mokhtari, S, Soavi, M, Tomas, V, Bregigeon, S, Faucher, O, Obry-Roguet, V, Ritleng, A, Petit, N, Bartoli, C, Ruiz, J, Blanc, D, Allegre, T, Sordage, M, Riou, J, Faudon, C, Slama, B, Zerazhi, H, Boulat, O, Chebrek, S, Beyrne, M, Granet Brunello, P, Pellissier, L, Bonnabel, D, Cohen Valensi, R, Mouchet, B, Mboungou, G, Lafeuillade, A, Hope-Rapp, E, Hittinger, G, Philip, G, Lambry, V, Raf, F, Allavena, C, Hall, N, Reliquet, V, Chidiac, C, Ferry, T, Perpoint, T, Miailhes, P, Boibieux, A, Livrozet, J, Makhlouf, D, Brunel, F, Chiarello, P, Hoen, B, Lamaury, I, Fabre, I, Samar, K, Duvallon, E, Clavel, C, Stegmann, S, Walter, V, Adriouch, L, Huber, F, Vanticlke, V, Couppie, P, Abel, S, Pierre-Francois, S, Ricaud, C, Rodet, R, Wartel, G, Sautron, C, Poubeau, P, Borgherini, G, Camuset, G, Arasteh, K, Kowohl Vivantes, S, Schurmann, D, Warncke Charite, M, Rockstroh, J, Wasmuth, J, Hass, S, Jensen, B, Feind, C, Esser, S, Schenk-Westkamp, P, Haberl, A, Stephan, C, Plettenberg, A, Kuhlendahl, F, Adam, A, Weitner, L, Schewe, K, Goey, H, Fenske, S, Buhk, T, Stellbrink, H, Hofmann, C, Hansen, S, Degen, O, Heuer, M, Stoll, M, Gerschmann, S, Horst, H, Trautmann, S, Gillor, D, Bogner, J, Sonntag, B, Salzberger, B, Fritzsche, C, 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Capparuccia, M, Iaiani, G, Latini, A, Gagliardini, R, Plazzi, M, De Girolamo, G, Vergori, A, Cecchetto, M, Viviani, F, De Vito, A, Rossetti, B, Montagnani, F, Franco, A, Fontana Del Vecchio, R, Di Giuli, C, Caramello, P, Orofno, G, Sciandra, M, Bassetti, M, Londero, A, Manfrin, V, Battagin, G, Starnini, G, Ialungo, A, van der Valk, M, Geerlings, S, Goorhuis, A, Hovius, J, Lempkes, B, Nellen, F, van der Poll, T, Prins, J, van Vugt, M, Wiersinga, W, Wit, F, van Duinen, M, van Eden, J, Hazenberg, A, van Hes, A, Pijnappel, F, Smalhout, S, Weijsenfeld, A, Jurriaans, S, Back, N, Zaaijer, H, Berkhout, B, Cornelissen, M, Schinkel, C, Wolthers, K, Peters, E, van Agtmael, M, Bomers, M, Sigalof, K, Heitmuller, M, Laan, L, Ang, C, van Houdt, R, Jonges, M, van Prehn, J, Kuijpers, T, Pajkrt, D, Scherpbier, H, de Boer, C, van der Plas, A, van den Berge, M, Stegeman, A, Baas, S, Hage de Loof, L, Wintermans, B, Veenemans, J, Pronk, M, Ammerlaan, H, de Munnik, E, Jansz, A, Tjhie, J, Wegdam, M, Deiman, B, Scharnhorst, V, van Eeden, A, Brokking, W, Elsenburg, L, Nobel, H, Damen, M, van Kasteren, M, Berrevoets, M, Brouwer, A, Adams, A, de Kruijf-Van de Wiel, B, Keelan-Pfaf, S, van der Ven, B, Buiting, A, Murck, J, Versteeg, D, de Vries-Sluijs, T, Bax, H, van Gorp, E, Nouwen, J, Rijnders, B, Schurink, C, Verbon, A, de Jong-Peltenburg, N, Bassant, N, van Beek, J, Vriesde, M, van Zonneveld, L, van den Berg-Cameron, H, de Groot, J, Boucher, C, Koopmans, M, van Kampen, J, Fraaij, P, van Rossum, A, Vermont, C, van der Knaap, L, Visser, E, Branger, J, Douma, R, Duijf-Van de Ven, C, Schippers, E, van Nieuwkoop, C, van IJperen, J, Geilings, J, van der Hut, G, van Burgel, N, Leyten, E, Gelinck, L, Mollema, F, Davids-Veldhuis, S, Wildenbeest, G, Heikens, E, Groeneveld, P, Bouwhuis, J, Lammers, A, Kraan, S, van Hulzen, A, Kruiper, M, van der Bliek, G, Bor, P, Bloembergen, P, Wolfagen, M, Ruijs, G, Kroon, F, de Boer, M, Scheper, H, Jolink, H, Dorama, W, van Holten, N, Claas, E, Wessels, E, den Hollander, J, El Moussaoui, R, Pogany, K, Kastelijns, M, Smit, J, Smit, E, Struik-Kalkman, D, Tearno, C, van Niekerk, T, Pontesilli, O, Lowe, S, Oude Lashof, A, Posthouwer, D, Ackens, R, Burgers, K, Schippers, J, Weijenberg-Maes, B, van Loo, I, Havenith, T, Weijer, S, van Vonderen, M, Kampschreur, L, Faber, S, Steeman-Bouma, R, Weel, J, Kootstra, G, Delsing, C, van der Burg-Van de Plas, M, Heins, H, Kortmann, W, van Twillert, G, Renckens, R, Ruiter-Pronk, D, van Truijen-Oud, F, Cohen Stuart, J, Jansen, E, Hoogewerf, M, Rozemeijer, W, van der Reijden, W, Sinnige, J, Brinkman, K, van den Berk, G, Blok, W, Frissen, P, Lettinga, K, Schouten, W, Veenstra, J, Vrouenraets, S, Brouwer, C, Geerders, G, Hoeksema, K, Kleene, M, Knapen, M, van der Meche, I, Mulder-Seeleman, E, Toonen, A, Wijnands, S, Kwa, D, van Crevel, R, van Aerde, K, Doferhof, A, Henriet, S, ter Hofstede, H, Hoogerwerf, J, Keuter, M, Richel, O, Albers, M, Grintjes-Huisman, K, de Haan, M, Marneef, M, Strik-Albers, R, Rahamat-Langendoen, J, Stelma, F, Burger, D, Gisolf, E, Hassing, R, Claassen, M, ter Beest, G, van Bentum, P, Langebeek, N, Tiemessen, R, Swanink, C, van Lelyveld, S, Soetekouw, R, van der Prijt, L, van der Swaluw, J, Bermon, N, Jansen, R, Herpers, B, Veenendaal, D, Verhagen, D, Lauw, F, van Broekhuizen, M, van Wijk, M, Bierman, W, Bakker, M, Kleinnijenhuis, J, Kloeze, E, Middel, A, Scholvinck, E, Stienstra, Y, Verhage, A, Wouthuyzen-Bakker, K, Boonstra, A, de Groot-De Jonge, H, van der Meulen, P, de Weerd, D, Niesters, H, van Leer-Buter, C, Knoester, M, Hoepelman, A, Arends, J, Barth, R, Bruns, A, Ellerbroek, P, Mudrikova, T, Oosterheert, J, de Regt, M, Schadd, E, van Zoelen, M, Aarsman, K, Grifoen-Van Santen, B, de Kroon, I, van Rooijen, C, van Berkel, M, Schuurman, R, Verduyn-Lunel, F, Wensing, A, Bont, L, Geelen, S, Loefen, Y, Wolfs, T, Nauta, N, Zaheri, S, Boyd, A, Bezemer, D, Smit, C, Hillebregt, M, de Jong, A, Woudstra, T, Bergsma, D, Meijering, R, van de Sande, L, Rutkens, T, van der Vliet, S, de Groot, L, van den Akker, M, Bakker, Y, El Berkaoui, A, Bezemer, M, Bretin, N, Djoechro, E, Geerlinks, J, Kruijne, E, Lodewijk, C, Lucas, E, van der Meer, R, Munjishvili, L, Paling, F, Peeck, B, Ree, C, Regtop, R, Ruijs, Y, Schoorl, M, Schnorr, P, Tuijn, E, Veenenberg, L, Witte, E, Tuk, B, Moreno, S, del Amo, J, Dalmau, D, Navarro, M, Gonzalez, M, Blanco, J, Garcia, F, Rubio, R, Iribarren, J, Gutierrez, F, Vidal, F, Berenguer, J, Gonzalez, J, Sobrino, P, Alejos, B, Alvarez, D, Jarrin, I, Moreno, C, Munoz-Fernandez, M, Garcia-Merino, I, Rico, C, de la Fuente, J, Torre, A, Portilla, J, Merino, E, Reus, S, Boix, V, Giner, L, Gadea, C, Portilla, I, Pampliega, M, Diez, M, Rodriguez, J, Sanchez-Paya, J, Podzamczer, D, Imaz, E, Van Den Eyncle, E, Di Yacovo, S, Sumoy, M, Gomez, J, Hernandez, J, Aleman, M, Alonso, M, Hernandez, M, Diaz-Flores, F, Garcia, D, Pelazas, R, Asensi, V, Valle, E, Carton, J, Perez, V, Molina, M, Garcia, J, Carrera, E, Pulido, F, Bisbal, O, Matarranz, M, Lagarde, M, Rubio-Martin, R, Hernando, A, Bermejo, L, Dominguez, L, Arrizabalaga, J, Aramburu, M, Camino, X, Rodriguez-Arrondo, F, von Wichmann, M, Tome, L, Goenaga, M, Bustinduy, M, Galparsoro, H, Ibarguren, M, Aguado, M, Umerez, M, Masia, M, Lopez, C, Padilla, S, Navarro, A, Montolio, F, Robledano, C, Colome, J, Adsuar, A, Pascual, R, Carlos, F, Martinez, M, Fernandez, M, Garcia, E, Muga, R, Tor, J, Sanvisens, A, Bernaldo de Quiros Lopez, J, Miralles, P, Gutierrez, I, Ramirez, M, Padilla, B, Gijon, P, Carrero, A, Aldamiz-Echevarria, T, Tejerina, F, Parras, F, Balsalobre, P, Diez, C, Peraire, J, Vilades, C, Veloso, S, Vargas, M, Lopez-Dupla, M, Olona, M, Aguilar, A, Sirvent, J, Alba, V, Calavia, O, Montero, M, Lacruz, J, Blanes, M, Calabuig, E, Cuellar, S, Lopez, J, Salavert, M, de la Serna, I, Arribas, J, Montes, M, Pena, J, Arribas, B, Castro, J, Zamora, J, Perez, I, Estebanez, M, Garcia, S, Diaz, M, Alcariz, N, Mingorance, J, Montero, D, Gonzalez, A, Isabel de Jose, M, de los Santos, I, Sanz, J, Salas, A, Sarria, C, Berrocal, A, Garcia-Fraile, L, Oteo, J, Ibarra, V, Metola, L, Sanz, M, Perez-Martinez, L, Pascual, A, Ramos, C, Arazo, P, Gil, D, Jaen, A, Cairo, M, Irigoyen, D, Jordano, Q, Xercavins, M, Martinez-Lacasa, J, Velli, P, Font, R, Sanmarti, M, Ibanez, L, Rivero, M, Casado, M, Diaz, J, Uriz, J, Reparaz, J, Irigoyen, C, Arraiza, M, Segura, F, Amengual, M, Navarro, G, Sala, M, Cervantes, M, Pineda, V, Segura, V, Anton, E, Nogueras, M, Casado, J, Dronda, F, Moreno, A, Elias, M, Lopez, D, Gutierrez, C, Madrid, N, Lamas, A, Marti, P, de Diaz, A, Serrrano, S, Donat, L, Cano, A, Bernal, E, Munoz, A, Pena, A, Munoz, L, Parra, J, Alvarez, M, Chueca, N, Guillot, V, Vinuesa, D, Fernandez, J, Del Romero, J, Rodriguez, C, Puerta, T, Carrio, J, Vera, M, Ballesteros, J, Domingo, P, Sambeat, M, Lamarca, K, Mateo, G, Gutierrez, M, Fernandez, I, Antela, A, Losada, E, Riera, M, Penaranda, M, Leyes, M, Ribas, M, Campins, A, Vidal, C, Gil, L, Fanjul, F, Marinescu, C, Ribera, E, Santos, J, Marquez, M, Viciana, I, Palacios, R, Gonzalez, C, Viciana, P, Leal, M, Lopez-Cortes, L, Espinosa, N, Munoz, J, Zubero, M, Baraia-Etxaburu, J, Ibarra, S, Ferrero, O, Lopez de Munain, J, Camara, M, Lopez, I, de la Pena, M, Suarez-Garcia, I, Malmierca, E, Olalla, J, del Arco, A, de la Torre, J, Prada, J, Caracuel, Z, Lopez-Lirola, A, Lozano, A, Fernandez, E, Martinez, O, Vera, F, Martinez, L, Alcaraz, B, Jimeno, A, Poveda, E, Pernas, B, Mena, A, Grandal, M, Castro, A, Pedreira, J, Galera, C, Albendin, H, Iborra, A, Campillo, M, Vidal, A, Amador, C, Pasquau, F, Ena, J, Benito, C, Fenoll, V, Mohamed-Balghata, M, Gomez, M, Alberto de Zarraga, M, Rivas, M, Gorgolas, M, Svedhem-Johansson, V, Flamholc, L, Gisslen, M, Hejdeman, B, Norgren, H, and Wendahl, S
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Male ,0301 basic medicine ,Psychological intervention ,Human immunodeficiency virus (HIV) ,Medizin ,Continuum of care ,Europe ,HIV infection ,Key population ,Sex ,Anti-Retroviral Agents ,Continuity of Patient Care ,European Union ,HIV ,Humans ,HIV Infections ,medicine.disease_cause ,key population ,0302 clinical medicine ,HIV Infection ,030212 general & internal medicine ,Men having sex with men ,media_common ,education.field_of_study ,[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology ,Transmission (medicine) ,Infectious Diseases ,AcademicSubjects/MED00290 ,HIV infection, continuum of care, sex, key population, Europe ,Microbiology (medical) ,Population ,Socio-culturale ,03 medical and health sciences ,Acquired immunodeficiency syndrome (AIDS) ,SDG 3 - Good Health and Well-being ,medicine ,media_common.cataloged_instance ,European union ,education ,Pandemics ,continuum of care ,sex ,business.industry ,SARS-CoV-2 ,COVID-19 ,medicine.disease ,030112 virology ,Major Articles and Commentaries ,Anti-Retroviral Agent ,business ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology ,Demography - Abstract
Background High uptake of antiretroviral treatment (ART) is essential to reduce human immunodeficiency virus (HIV) transmission and related mortality; however, gaps in care exist. We aimed to construct the continuum of HIV care (CoC) in 2016 in 11 European Union (EU) countries, overall and by key population and sex. To estimate progress toward the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 target, we compared 2016 to 2013 estimates for the same countries, representing 73% of the population in the region. Methods A CoC with the following 4 stages was constructed: number of people living with HIV (PLHIV); proportion of PLHIV diagnosed; proportion of those diagnosed who ever initiated ART; and proportion of those ever treated who achieved viral suppression at their last visit. Results We estimated that 87% of PLHIV were diagnosed; 92% of those diagnosed had ever initiated ART; and 91% of those ever on ART, or 73% of all PLHIV, were virally suppressed. Corresponding figures for men having sex with men were: 86%, 93%, 93%, 74%; for people who inject drugs: 94%, 88%, 85%, 70%; and for heterosexuals: 86%, 92%, 91%, 72%. The proportion suppressed of all PLHIV ranged from 59% to 86% across countries. Conclusions The EU is close to the 90-90-90 target and achieved the UNAIDS target of 73% of all PLHIV virally suppressed, significant progress since 2013 when 60% of all PLHIV were virally suppressed. Strengthening of testing programs and treatment support, along with prevention interventions, are needed to achieve HIV epidemic control., Standardized definitions were used to estimate a 4-stage continuum of human immunodeficiency virus (HIV) care in 11 European Union (EU) countries in 2016. The EU is close to the 90-90-90 target, with the main challenge being the percentage of undiagnosed infections.
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- 2020
25. Increasing Influenza Immunization Rates Among Retail Employees: An Evidence-Based Approach
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Montejo, Leigh, Richesson, Rachel, Padilla, B. Iris, Zychowicz, Michael E., and Hambley, Crystal
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- 2017
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26. An algorithm to diagnose influenza infection: evaluating the clinical importance and impact on hospital costs of screening with rapid antigen detection tests
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González-Del Vecchio, M., Catalán, P., de Egea, V., Rodríguez-Borlado, A., Martos, C., Padilla, B., Rodríguez-Sanchez, B., and Bouza, E.
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- 2015
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27. AB0905 Routine Assessment of Patient Index Data 3 (RAPID3) in Patients With Active Psoriatic Arthritis (PsA) After Inadequate Response or Intolerance to DMARDs: Pooled Results From the Phase 3, Randomized, Double-Blind KEEPsAKE 1 and 2 Trials
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Ogdie, A., primary, Coates, L., additional, Acayaba DE Toledo, R., additional, Biljan, A., additional, Jones, H., additional, Tacelosky, K., additional, Yue, C., additional, Padilla, B., additional, and Bergman, M., additional
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- 2022
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28. POS1032 RISANKIZUMAB FOR ACTIVE PSORIATIC ARTHRITIS: INTEGRATED SUBGROUP ANALYSIS FROM 2 DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE 3 STUDIES (KEEPsAKE 1 AND KEEPsAKE 2)
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Merola, J. F., primary, Callis-Duffin, K., additional, Padilla, B., additional, Xue, Z., additional, Photowala, H., additional, Kaplan, B., additional, and Mcinnes, I., additional
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- 2022
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29. POS1036 EFFICACY AND SAFETY OF RISANKIZUMAB (RZB) FOR ACTIVE PSORIATIC ARTHRITIS (PsA): 52-WEEK RESULTS FROM KEEPsAKE 2
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Ostor, A., primary, Van den Bosch, F., additional, Papp, K., additional, Asnal, C., additional, Blanco, R., additional, Aelion, J., additional, Lu, W., additional, Wang, Z., additional, Soliman, A. M., additional, Eldred, A., additional, Padilla, B., additional, and Kivitz, A., additional
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- 2022
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30. POS1057 IMPACT OF RISANKIZUMAB ON ENTHESITIS AND ASSOCIATED PAIN: POOLED RESULTS FROM THE PHASE 3, RANDOMIZED, DOUBLE-BLIND KEEPsAKE 1 AND 2 TRIALS
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Magrey, M., primary, Jain, M., additional, Ranza, R., additional, Stigler, J., additional, Mcdearmon-Blondell, E., additional, Yue, C., additional, Padilla, B., additional, Kaufmann, C., additional, and Mcgonagle, D., additional
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- 2022
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31. Portuguese migrations to South America after world war II: Extending citizenship abroad
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Padilla, B., França, T., Maria Damilakou, and Yannis G. S. Papadopoulos
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info:eu-repo/semantics/publishedVersion
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- 2022
32. Prolonged viral shedding in pandemic influenza A(H1N1): clinical significance and viral load analysis in hospitalized patients
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Giannella, M., Alonso, M., Garcia de Viedma, D., Lopez Roa, P., Catalán, P., Padilla, B., Muñoz, P., and Bouza, E.
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- 2011
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33. Impact of fluconazole susceptibility on the outcome of patients with candidaemia: data from a population-based surveillance
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Padilla, B., Muñoz, P., Guinea, J., Paño Pardo, J.R., García-Rodríguez, J., Cerrada, C.G., Fortún, J., Martín, P., Gómez, E., Ryan, P., Campelo, C., de los Santos Gil, I., Buendía, V., Gorricho, B.P., Alonso, M., Sanz, F.S., Aguado, J.M., Merino, P., González Romo, F., Gorgolas, M., Gadea, I., Losa, J.E., Delgado-Iribarren, A., Ramos, A., Romero, Y., Romero, I.S., Zaragoza, O., Cuenca-Estrella, M., Rodríguez-Baño, J., Suarez, A.I., Loza, A., Aller García, A.I., Martín-Mazuelos, E., Pérez de Pipaón, M.R., Garnacho, J., Ortiz, C., Chávez, M., Maroto, F.L., Salavert, M., Pemán, J., Blanquer, J., Navarro, D., Camarena, J.J., Zaragoza, R., Abril, V., Gimeno, C., Hernández, S., Ezpeleta, G., Bereciartua, E., Hernández Almaraz, J.L., Montejo, M., Rivas, R.A., Ayarza, R., Planes, A.M., Camps, I.R., Almirante, B., Mensa, J., Almela, M., Gurgui, M., Sánchez-Reus, F., Martínez-Montauti, J., Sierra, M., Horcajada, J.P., Sorli, L., Gómez, J., Gené, A., Urrea, M., Mularoni, A., Valerio, M., Díaz-Martín, A., Puchades, F., Fernández-Ruiz, M., Lora-Pablos, D., Zaragoza, Ó., and Puig-Asensio, M.
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- 2017
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34. Evaluation of the possible influence of trailing and paradoxical effects on the clinical outcome of patients with candidemia
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Padilla, B., Muñoz, P., Guinea, J., Paño Pardo, J.R., García-Rodríguez, J., García Cerrada, C., Fortún, J., Martín, P., Gómez, E., Ryan, P., Campelo, C., de los Santos Gil, I., Buendía, V., Gorricho, B.P., Alonso, M., Sanz, F.S., Aguado, J.M., Merino, P., González Romo, F., Gorgolas, M., Gadea, I., Losa, J.E., Delgado-Iribarren, A., Ramos, A., Romero, Y., Sánchez Romero, I., Zaragoza, O., Cuenca-Estrella, M., Rodriguez-Baño, J., Isabel Suarez, A., Loza, A., Aller García, A.I., Martín-Mazuelos, E., Pérez de Pipaón, M.R., Garnacho, J., Ortiz, C., Chávez, M., Maroto, F.L., Salavert, M., Pemán, J., Blanquer, J., Navarro, D., Camarena, J.J., Zaragoza, R., Abril, V., Gimeno, C., Hernáez, S., Ezpeleta, G., Bereciartua, E., Hernández Almaraz, J.L., Montejo, M., Rivas, R.A., Ayarza, R., Planes, A.M., Camps, I.R., Almirante, B., Mensa, J., Almela, M., Gurgui, M., Sánchez-Reus, F., Martinez-Montauti, J., Sierra, M., Horcajada, J.P., Sorli, L., Gómez, J., Gené, A., Urrea, M., Valerio, M., Díaz-Martín, A., Puchades, F., Mularoni, A., Rueda, C., and Puig-Asensio, M.
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- 2017
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35. Emergence of resistance to daptomycin in a cohort of patients with methicillin-resistant Staphylococcus aureus persistent bacteraemia treated with daptomycin
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Gasch, O., Camoez, M., Domínguez, M. A., Padilla, B., Pintado, V., Almirante, B., Martín, C., López-Medrano, F., de Gopegui, E. Ruiz, Blanco, J. R., García-Pardo, G., Calbo, E., Montero, M., Granados, A., Jover, A., Dueñas, C., Pujol, M., Jover, A., Barcenilla, F., García, M., Pujol, M., Gasch, O., Domínguez, M. A., Camoez, M., Dueñas, C., Ojeda, E., Martínez, J. A., Marco, F., Chaves, F., Lagarde, M., López-Medrano, F., Montejo, J. M., Bereciertua, E., Hernández, J. L., von Wichmann, M. Á., Goenaga, A., García-Arenzana, J. M., Padilla, B., Padilla, C., Cercenado, E., García-Prado, G., Tapiol, J., Horcajada, J. P., Montero, M., Salvadó, M., Arnáiz, A., Fernández, C., Calbo, E., Xercavins, M., Granados, A., Fontanals, D., Pintado, V., Loza, E., Torre-Cisneros, J., Lara, R., Rodríguez-López, F., Rodríguez, M., Natera, C., Blanco, J. R., Olarte, I., Benito, N., Mirelis, B., Murillas, J., Ruiz de Gopegui, E., Espejo, H., Morera, M. A., Rodríguez-Baño, J., López-Cortés, L. E., Pascual, A., Martín, C., Lepe, J. A., Molina, J., Sordé, R., Almirante, B., and Larrosa, N.
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- 2014
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36. CORRECCIÓN DE RUIDO TEMPORAL Y ESPACIAL ORIENTADO A LA MAXIMIZACIÓN DE CONTRASTE Y COMPENSACIÓN DE ILUMINACIÓN EN IMÁGENES INFRARROJAS
- Author
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Jaramillo-I, Alejandro, primary, Padilla-B, José Bestier, primary, and Arango, Ramiro, primary
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- 2021
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37. Amélioration des PRO (« Patient-Reported Outcomes ») chez les patients traités par risankizumab pour un rhumatisme psoriasique actif présentant une résolution de l’enthésite et/ou de la dactylite : analyses post hoc des études KEEPsAKE 1 et 2
- Author
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Kwatra, S.G., Khattri, S., Amin, A., Liu, R., Padilla, B., Soliman, A.M., Kaplan, B., Goupille, P., and Mcgonagle, D.
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- 2023
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38. HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients
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Brochado Kith, Óscar, Martínez, Isidoro, Berenguer, Juan, Medrano, Luz María, González-García, Juan, Jiménez-Sousa, María Ángeles, Carrero, Ana, Hontañón Antoñana, Víctor, Navarro, Jordi, Guardiola Tey, Jose Maria, Fernández-Rodríguez, Amanda, Resino, Salvador, Miralles, P., López, J.C., Parras, F., Padilla, B., Aldámiz-Echevarría, T, Tejerina, F., Díez, C., Pérez-Latorre, L., Fanciulli, C., Gutiérrez, I., Ramírez, M., Carretero, S., Bellón, J.M., Bermejo, Javier, Arribas, J. R., Montes, M.L., Bernardino, I., Pascual, J.F., Zamora, Francisco, Peña, J.M., Arnalich, F., Díaz, M., Domingo, Pere, Van den Eynde, E., Pérez, M., Ribera, E., Crespo, M., Casado, J.L., Dronda, F., Moreno, A., Pérez-Elías, M.J., Sanfrutos, M.A., Moreno, S., Quereda, C., Arranz, A., Casas, E., de Miguel, J., Schroeder, S., Sanz, J., Santos, I., Bustinduy, M.J., Iribarren, J.A., Rodríguez-Arrondo, F., Von-Wichmann, M.A., Vergas, J., Téllez, M.J., Vinuesa, D., Muñoz, L., Hernández-Quero, J., Ferrer, A., Galindo, M.J., Ortiz, L., Ortega, E., Montero, M., Blanes, M., Cuellar, S., Lacruz, J., Salavert, M., López-Aldeguer, J., Pérez, G., Gaspar, G., Yllescas, M., Crespo, P., Aznar, E., Esteban, H., Instituto de Salud Carlos III, European Regional Development Fund (ERDF/FEDER), Ministerio de Ciencia e Innovación, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Ministerio de Ciencia e Innovación (España), Institut Català de la Salut, [Brochado Ó, Martínez I, Medrano L, Jiménez-Sousa MÁ] Unidad de Infección Viral E Inmunidad, Centro Nacional de Microbiología, Instituto de Salud Carlos III (Campus Majadahonda), Madrid, Spain. [Berenguer J] Unidad de Enfermedades Infecciosas/VIH, Hospital General Universitario 'Gregorio Marañón', Madrid, Spain. Instituto de Investigación Sanitaria del Gregorio Marañón, Madrid, Spain. [González-García J] Unidad de VIH, Servicio de Medicina Interna, Hospital Universitario 'La Paz', Madrid, Spain. Instituto de Investigacion Sanitaria La Paz (IdiPAZ), Madrid, Spain. [Navarro J] Servei de Malalties Infeccioses, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain, and Vall d'Hebron Barcelona Hospital Campus
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Male ,0301 basic medicine ,Endocrinology, Diabetes and Metabolism ,Clinical Biochemistry ,lcsh:Medicine ,Gene Expression ,HIV Infections ,Hepacivirus ,medicine.disease_cause ,0302 clinical medicine ,Interferon ,Medicine ,Pharmacology (medical) ,Other subheadings::/therapeutic use [Other subheadings] ,Interferon therapy ,Coinfection ,virus diseases ,Genetic Phenomena::Gene Expression [PHENOMENA AND PROCESSES] ,General Medicine ,Hepatitis C ,Middle Aged ,Interferó - Ús terapèutic ,Hepatocellular carcinoma ,Female ,030211 gastroenterology & hepatology ,medicine.drug ,Adult ,Hepatitis C virus ,Peripheral blood mononuclear cell ,Virus ,HCV clearance ,aminoácidos, péptidos y proteínas::péptidos::péptidos y proteínas de señalización intercelular::citocinas::interferones [COMPUESTOS QUÍMICOS Y DROGAS] ,03 medical and health sciences ,Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interferons [CHEMICALS AND DRUGS] ,Immune system ,Humans ,Molecular Biology ,Virus Diseases::Coinfection [DISEASES] ,Otros calificadores::/uso terapéutico [Otros calificadores] ,business.industry ,virosis::coinfección [ENFERMEDADES] ,Research ,lcsh:R ,Biochemistry (medical) ,HIV ,Cell Biology ,medicine.disease ,Expressió gènica ,HIV/HCV coinfection ,030104 developmental biology ,Virosis ,PBMCs ,Immunology ,Leukocytes, Mononuclear ,Gene expression ,Interferons ,business ,fenómenos genéticos::expresión génica [FENÓMENOS Y PROCESOS] - Abstract
Coinfecció pel VIH/VHC; Sistema immunitari; Teràpia amb interferó Coinfección por VIH/VHC; Sistema inmunitario; Terapia con interferón HIV/HCV coinfection; Immune system; Interferon therapy Objective To evaluate the impact of hepatitis C virus (HCV) elimination via interferon (IFN)-based therapy on gene expression profiles related to the immune system in HIV/HCV-coinfected patients. Methods We conducted a prospective study in 28 HIV/HCV-coinfected patients receiving IFN-based therapy at baseline (HIV/HCV-b) and week 24 after sustained virological response (HIV/HCV-f). Twenty-seven HIV-monoinfected patients (HIV-mono) were included as a control. RNA-seq analysis was performed on peripheral blood mononuclear cells (PBMCs). Genes with a fold-change (FC) ≥ 1.5 (in either direction) and false discovery rate (FDR) ≤ 0.05 were identified as significantly differentially expressed (SDE). Results HIV/HCV-b showed six SDE genes compared to HIV-mono group, but no significantly enriched pathways were observed. For HIV/HCV-f vs. HIV/HCV-b, we found 58 SDE genes, 34 upregulated and 24 downregulated in the HIV/HCV-f group. Of these, the most overexpressed were CXCL2, PDCD6IP, ATP5B, IGSF9, RAB26, and CSRNP1, and the most downregulated were IFI44 and IFI44L. These 58 SDE genes revealed two significantly enriched pathways (FDR
- Published
- 2021
39. Empirical and targeted therapy of candidemia with fluconazole versus echinocandins: a propensity score–derived analysis of a population-based, multicentre prospective cohort
- Author
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Padilla, B., Muñoz, P., Guinea, J., Paño Pardo, J.R., García-Rodríguez, J., García Cerrada, C., Fortún, J., Martín, P., Gómez, E., Ryan, P., Campelo, C., de los Santos Gil, I., Buendía, V., Pérez Gorricho, B., Alonso, M., Sanz Sanz, F., María Aguado, J., Merino, P., González Romo, F., Gorgolas, M., Gadea, I., Losa, J.E., Delgado-Iribarren, A., Ramos, A., Romero, Y., Sánchez Romero, I., Zaragoza, O., Cuenca-Estrella, M., Rodríguez-Baño, J., Suarez, A.I., Loza, A., Aller García, A.I., Martín-Mazuelos, E., Pérez de Pipaón, M.R., Garnacho, J., Ortiz, C., Chávez, M., Maroto, F.L., Salavert, M., Pemán, J., Blanquer, J., Navarro, D., Camarena, J.J., Zaragoza, R., Abril, V., Gimeno, C., Hernáez, S., Ezpeleta, G., Bereciartua, E., Hernández Almaraz, J.L., Montejo, M., Rivas, R.A., Ayarza, R., Planes, A.M., Ruiz Camps, I., Almirante, B., Mensa, J., Almela, M., Gurgui, M., Sánchez-Reus, F., Martinez-Montauti, J., Sierra, M., Horcajada, J.P., Sorli, L., Gómez, J., Gené, A., Urrea, M., Valerio, M., Díaz-Martín, A., Puchades, F., Mularoni, A., López-Cortés, L.E., Garnacho-Montero, J., Puig-Asensio, M., and Ruiz-Camps, I.
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- 2016
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40. PCN83 Healthcare Resource Utilization (HCRU) of Patients with Resected Esophageal Cancer or Gastroesophageal Junction Cancer (EC/GEJC) Receiving Adjuvant Nivolumab Treatment Versus Placebo
- Author
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Lawrance, R., primary, Singh, P., additional, Leso, A., additional, Moreno-Koehler, A., additional, Padilla, B., additional, Sun, X., additional, Taylor, F., additional, and Blum, S., additional
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- 2021
- Full Text
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41. Tecendo experiências migratórias: brasileiras em Portugal: entre o preconceito e a sexualização
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França, T., Padilla, B., Gláucia de Oliveira Assis, Thais França, and Beatriz Padilla
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Ciências Sociais::Sociologia [Domínio/Área Científica] ,Migração de gênero ,Mobilidade humana ,Migração transnacional - Abstract
A partir de finais da década de 1990, a imigração brasileira para Portugal ganhou uma visibilidade inédita. Numericamente, os/as imigrantes brasileiros/as cresceram de uma forma inesperada, passando de um grupo que representava cerca de 11% em 1991 para tornar-se a maior população de imigrantes no país a partir do ano de 2006, e permanecendo nesta posição até os dias de hoje. Em 2014, representavam 22% do total dessa população (MALHEIROS, 2007; SEF, vários anos). A partir de então, diversos estudos e investigações (FRANÇA, 2012; GÓIS et al., 2009; GOMES, 2013; MACHADO, 2009; MALHEIROS, 2007; PADILLA, 2007b; PEIXOTO, 2007; PINHO, 2014) foram conduzidos para conhecer as especificidades dessa corrente migratória. info:eu-repo/semantics/publishedVersion
- Published
- 2021
42. Gênero e mobilidades no tempo presente
- Author
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Assis, G., Padilla, B., and França, T.
- Abstract
O tema da feminização das migrações tem sido construído a partir de diferentes olhares e dimensões neste século XXI. Este livro aprofunda aspectos relativos às questões de gênero, sexualização, preconceitos, identidades, subjetividades, redes migratórias, associativismo, moradia, empreendedorismo, família, trabalho, raça, casamentos, nacionalidades e os espaços onde se processam as migrações transnacionais. Um fio condutor entre os estudos que compõem esta obra está pautado na visibilidade da presença de mulheres nos processos migratórios. A visibilidade entendida como agência traz novas interpretações ao fenômeno migratório e aponta para as diferenças entre os percursos e projetos migratórios para mulheres e homens. Reconhecer a presença de mulheres nas migrações imprime a construção da visibilidade social, caminho para a desconstrução de estigmas, discriminação e preconceitos. De fato, Norbert Elias nos faz refletir sobre a naturalização da ação invisibilisadora, a partir da qual o estigma cria estereótipos, reforçando-se na violência simbólica e na relação entre a invisibilidade social e a construção da identidade dos sujeitos. Entender o estigma, segundo Goffman, como uma linguagem de relações implica considerar que a percepção de si está relacionada ao julgamento do grupo em que se convive. Assim, com o olhar conceitual para a visibilidade social da migração de mulheres, minha leitura dos capítulos deste livro remete considerar a representação social de mulheres imigrantes nos variados contextos contemplados nos estudos, como Portugal, Itália, República Dominicana, espaços de fronteiras Argentina-Paraguai de Posadas (Misiones, República Argentina) e Encarnación (Itapúa, República do Paraguai), Espanha, Argentina, Estados Unidos, Alemanha, Londres e Brasil. Nesse sentido, esta obra torna-se referência obrigatória para se avançar na compreensão dos processos migratórios de mulheres no mundo contemporâneo. info:eu-repo/semantics/publishedVersion
- Published
- 2021
43. Mental health of refugees and migrants during the covid-19 pandemic: The role of experienced discrimination and daily stressors
- Author
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Spiritus-Beerden, E. Verelst, A. Devlieger, I. Primdahl, N.L. Guedes, F.B. Chiarenza, A. De Maesschalck, S. Durbeej, N. Garrido, R. de Matos, M.G. Ioannidi, E. Murphy, R. Oulahal, R. Osman, F. Padilla, B. Paloma, V. Shehadeh, A. Sturm, G. van den Muijsenbergh, M. Vasilikou, K. Watters, C. Willems, S. Skovdal, M. Derluyn, I.
- Abstract
The COVID-19 pandemic is a defining global health crisis of our time. While the impact of COVID-19, including its mental health impact, is increasingly being documented, there remain important gaps regarding the specific consequences of the pandemic on particular population groups, including refugees and migrants. This study aims to uncover the impact of the COVID-19 pandemic on the mental health of refugees and migrants worldwide, disentangling the possible role of social and daily stressors, i.e., experiences of discrimination and daily living conditions. Descriptive analysis and structural equation modeling were used to analyze the responses of N = 20,742 refugees and migrants on the self-reporting global ApartTogether survey. Survey findings indicated that the mental health of refugees and migrants during the COVID-19 pandemic was significantly impacted, particularly for certain subgroups, (i.e., insecure housing situation and residence status, older respondents, and females) who reported experiencing higher levels of increased discrimination and increases in daily life stressors. There is a need to recognize the detrimental mental health impact of the COVID-19 pandemic on particular refugee and migrant groups and to develop interventions that target their unique needs. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
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- 2021
44. Immigration, integration, and citizenship policies in Portugal: The case of health in the 21st century
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Asensio, M. and Padilla, B.
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Inmigration policy ,Policy gaps ,Social rights ,Ciências Sociais::Ciências Políticas [Domínio/Área Científica] - Abstract
This article investigates to what extent immigration is confronting the Welfare States with citizenship limitations as citizenship has been called into question by immigration, globalization, and the increasing internal debate of political communities. This case study of immigration in Portugal examines the contradiction between the rhetoric of immigrant integration portrayed by the State and the reality of immigrant exclusion. Existing research highlights the importance of international human rights frameworks as a catalyst for governments’ recognition of immigrants’ social rights. The study of Portuguese immigration policy on which this article is based was undertaken as a way to explore such apparent contradictions. As a Southern European country that has undergone an enormous political and economic transformation in the last three decades, experiencing the contradictions of advanced capitalist societies in an intensified way, Portugal offers an interesting case study for such analysis. This article aims to fill this gap. As we will see, the health policy on immigrants in Portugal can illuminate not only the contradictions of Portuguese society but also the broader contradictions of the Welfare State in the new global economy. info:eu-repo/semantics/publishedVersion
- Published
- 2021
45. Impact on knowledge and practice of an intervention to control catheter infection in the ICU
- Author
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Guembe, M., Pérez-Parra, A., Gómez, E., Sánchez-Luna, M., Bustinza, A., Zamora, E., Carrillo-Álvarez, A., Cuenca, A., Padilla, B., Martín-Rabadán, P., Bouza, E., and on behalf of the GEIDI Study Group
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- 2012
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46. Antifungal stewardship in a tertiary-care institution: a bedside intervention
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Valerio, M., Muñoz, P., Rodríguez, C.G., Caliz, B., Padilla, B., Fernández-Cruz, A., Sánchez-Somolinos, M., Gijón, P., Peral, J., Gayoso, J., Frias, I., Salcedo, M., Sanjurjo, M., and Bouza, E.
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- 2015
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47. Políticas migratórias em Portugal: complexidade e hiatos entre a lei e a prática
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Padilla, B., França, T., Luiz Carlos Ribeiro, and Márcio de Oliveira
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Portugal ,Políticas migratória - Abstract
A entrada de Portugal na União Europeia nos anos de 1980, juntamente com o aumento dos fluxos de imigração para o país deram início a um conjunto de mudanças fundamentais nas políticas migratórias nacionais. Entre essas mudanças destacam-se a legislação sobre o controle de entrada, permanência e saída de imigrantes do território nacional e mais recentemente a legislação acerca da integração desses imigrantes à sociedade portuguesa. A evolução dessas políticas tem concedido à Portugal um reconhecimento internacional como um país acolhedor e aberto à diversidade cultural. A partir da análise qualitativa de algumas dessas políticas – nomeadamente a lei da imigração que regula a entrada/saída de imigrantes, a lei de aquisição de nacionalidade e a legislação antidiscriminação -, o presente capítulo tem como objetivo discutir o papel do próprio Estado português, da União Europeia e da sociedade civil na concepção dessas políticas. info:eu-repo/semantics/submittedVersion
- Published
- 2020
48. Multicomponent Exercise Training Combined with Nutritional Counselling Improves Physical Function, Biochemical and Anthropometric Profiles in Obese Children: A Pilot Study
- Author
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Cordellat A, Padilla B, Grattarola P, Garcia-Lucerga C, Crehua-Gaudiza E, Nunez F, Martinez-Costa C, and Blasco-Lafarga C
- Abstract
Aerobics or strength exercise plus diet interventions have been shown to counteract childhood obesity. However, little is known with regard to periodized multicomponent exercise interventions combined with nutritional counselling, which might be less demanding but more enjoyable and respectful of children and adolescents' nature. In order to analyze the impact of such a multimodal approach, 18 obese children (10.8 ± 1.6 years; 63% females; z Body Mass Index 3 ± 0.4) trained for 60 min, twice weekly and were measured for body composition, biochemical parameters and physical function. We found that 16 weeks of multimodal intervention (14 of training), based on fun-type skill-learning physical activities and physical conditioning with challenging circuits and games, together with nutritional counselling, led to an attendance > 80%, with significant overall health improvement. Body composition was enhanced (p < 0.01 for z BMI, mid-upper-arm-circumference, waist-to-height ratio, tricipital and subscapular skinfolds, body-fat % by Slaughter equation and Dual energy X-ray absorptiometry body fat% and trunk fat%), as well as metabolic profile (LDL cholesterol, gamma-glutamyl transferase , alanine aminotransferase ; p < 0.05), homeostatic model assessment of insulin resistance (HOMA-IR; p < 0.05) and inflammatory response (C-Reactive Protein; p < 0.05). Physical fitness was also improved (p < 0.01) through better cardiovascular test scores and fundamental movement patterns (Functional Movement Screen-7, FMS-4). Tailoring multimodal supervised strategies ensured attendance, active participation and enjoyment, compensating for the lack of strict caloric restrictions and the low volume and training frequency compared to the exercise prescription guidelines for obesity. Nutritional counselling reinforced exercise benefits and turned the intervention into a powerful educational strategy. Teamwork and professionals' specificity may also be key factors.
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- 2020
49. Mild profile improvement of immune biomarkers in HIV/HCV-coinfected patients who removed hepatitis C after HCV treatment: A prospective study
- Author
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Garcia-Broncano, P, Medrano, LM, Berenguer, J, Brochado-Kith, O, Gonzalez-Garcia, J, Jimenez-Sousa, A, Quereda, C, Sanz, J, Tellez, MJ, Diaz, L, JImenez, JL, Resino, S, Carrero, A, Miralles, P, Lopez, JC, Parras, F, Padilla, B, Aldamiz-Echevarria, T, Tejerina, F, Diez, C, Perez-Latorre, L, Fanciulli, C, Gutierrez, I, Ramirez, M, Carretero, S, Bellon, JM, Bermejo, J, Hontanon, V, Arribas, JR, Montes, ML, Bernardino, I, Pascual, JF, Zamora, F, Pena, JM, Arnalich, F, Diaz, M, Domingo, P, Guardiola, JM, Van den Eynde, E, Perez, M, Ribera, E, Crespo, M, Casado, JL, Dronda, F, Moreno, A, Perez-Elias, MJ, Sanfrutos, MA, Moreno, S, Arranz, A, Casas, E, de Miguel, J, Schroeder, S, Santos, I, Bustinduy, MJ, Iribarren, JA, Rodriguez-Arrondo, F, Von-Wichmann, MA, Vergas, J, Vinuesa, D, Munoz, L, Hernandez-Quero, J, Ferrer, A, Galindo, MJ, Ortiz, L, Ortega, E, Montero, M, Blanes, M, Cuellar, S, Lacniz, J, Salavert, M, Lopez-Aldeguer, J, Perez, G, Gaspar, G, Yllescas, M, Crespo, P, Aznar, E, Esteban, H, and GESIDA 3603b Study Grp
- Subjects
Inflammation ,Immune activation ,virus diseases ,HIV ,HCV therapy ,Chronic hepatitis C ,digestive system diseases ,Biomarkers - Abstract
Objective: There are a lack of consistency among articles in regards to the evolution of peripheral immune biomarkers after HCV therapy. We aimed to detect the most relevant changes in peripheral immune biomarkers among HIV/HCV-coinfected patients who achieved sustained virologic response (SVR) following peg-IFN-alpha/ribavirin therapy and to evaluate its normalization with respect to an HIV-monoinfected control group. Methods: We performed a prospective cohort study in 99 HIV/HCV-coinfected patients with samples at baseline (HIV/HCV-b-group) and at week 24 after SVR (HIV/HCV-f-group). We also used a control group of 39 HIV-monoinfected patients (HIV-group) negative for HCV and HBV infections, and who had undetectable HIV viral load and CD4(+) >500 cells/mm(3). Peripheral T cell subsets were assessed by flow cytometry and plasma biomarkers by immunoassays. Results: HIV/HCV-coinfected patients had higher values of in IL-10, IL-4, IP-10, IL-8, IL-1 beta, IL-18, IL-6, IFN-gamma, IL-12p70, TNF-alpha, sVCAM-1, sICAM-1, and sTNFR-1 than HIV control subjects, both at the beginning and at the end of follow-up. Moreover, three biomarkers (CD4(+)CD38(+), telomere length, and IL-1RA) were normalized in relation to the control group at the end of follow-up (the HIV/HCV-b group had higher values and the HIV/HCV-f group had similar values as the HIV-group). Additionally, LPS, IL-2, and IL-17A levels were higher in the HIV/HCV-f group than the HIV-group (24 weeks after SVR). During the follow-up, HIV/HCV-coinfected patients had a significant decrease by the end of follow-up in CD8(+)CD45RA(-)CD28(+), CD4(+)CD38(+), CD4(+)CD25(+)CD127(-/lo)(w), CD4(+)CD25(+)CD127(-/low) CD45RA(-), FABP2, LBP, IP-10, sVCAM1. Only CD4(+)CD38(+) was normalized. Conclusion: HIV/HCV-patients showed a slight improvement in the overall profile of immune biomarkers after achieving SVR. (C) 2019 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
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- 2020
50. DETECCIÓN DE FATIGA AL CONDUCIR UTILIZANDO TÉCNICAS DE VISIÓN POR COMPUTADOR
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Alejandro Jaramillo I, José Bestier Padilla B, and Ramiro Arango
- Subjects
Modelos de forma activa ,Ajuste ,Modelo Paramétrico ,PERCLOS ,AECS ,Technology (General) ,T1-995 ,General Works ,Social sciences (General) ,H1-99 - Abstract
La fatiga al conducir es uno de las principales causas de accidentes de tránsito. Los sistemas de detección de fatiga basados en visión por computador tienen gran potencial dada su característica de no-invasividad. Los principales desafíos que se presentan son los movimientos rápidos de ojos y boca, cambios de pose y variacio-nes de iluminación. En este trabajo se entrena un Modelo de Forma Activa para la detección de características faciales extraídas del modelo paramétrico Candide-3. Se describe la metodología de caracterización a partir del modelo paramétrico. Se evalúan de forma cuantitativa la exactitud en: la detección de características y la estimación de los parámetros asociados a la fatiga; analizando su robustez a variaciones de pose y variaciones locales de las regiones de interés. El modelo utilizado y la metodología de caracterización mostraron eficiencia para detectar la fatiga en el 100% de los casos evaluados.
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- 2012
- Full Text
- View/download PDF
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