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Objective: To analyze the impact, performance, degree of specialization, and collaboration patterns of the worldwide scientific production on tissue engineering in otorhinolaryngology at the level of countries and institutions. Methods: Two different techniques were used, performance and science mapping analyses, using as samples all the available documents regarding tissue engineering focused on otorhinolaryngology applications. The dataset was retrieved from the Core Collection of the Web of Science database from 1900 to 2020. Social structure was analyzed using science mapping analysis with VOSviewer software. Results: The United States was the main producer, followed by Germany, and Japan. Malaysia and Germany had the highest Relative Specialization Index, indicating their greater relative interest in this area compared to other countries. The social structure analysis showed that the United States and Germany had significant co‐authorship relationships with other countries. The University of California System, Kyoto University, and Harvard University were the leading institutions producing literature in this field. These latter two institutions showed the largest number of collaborations, although most of them were with institutions within their own country. There was a lack of connections between different communities of research. Conclusion: The United States is the main country driving progress in this research area, housing the most notable institutions. However, significant collaborations between these research centers are currently lacking. Encouraging greater cooperation among these institutions and their researchers would promote the exchange of knowledge, ultimately facilitating and accelerating advancements in this field. [ABSTRACT FROM AUTHOR]

Translational medicine is an important area of biomedicine, and has significantly facilitated the development of biomedical research. Despite its relevance, there is no consensus on how to evaluate its progress and impact. A systematic review was carried out to identify all the methods to evaluate translational research. Seven methods were found according to the established criteria to analyze their characteristics, advantages, and limitations. They allow us to perform this type of evaluation in different ways. No relevant advantages were found between them; each one presented its specific limitations that need to be considered. Nevertheless, the Triangle of Biomedicine could be considered the most relevant method, concerning the time since its publication and usefulness. In conclusion, there is still a lack of a gold-standard method for evaluating biomedical translational research., Competing Interests: None., (AJTR Copyright © 2022.)