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973 results on '"Padilla, Jose"'

2. Broadening Access to Simulations for End-Users via Large Language Models: Challenges and Opportunities

Author

Giabbanelli, Philippe J., Padilla, Jose J., and Agrawal, Ameeta

Subjects
Computer Science - Human-Computer Interaction, Computer Science - Artificial Intelligence
Abstract

Large Language Models (LLMs) are becoming ubiquitous to create intelligent virtual assistants that assist users in interacting with a system, as exemplified in marketing. Although LLMs have been discussed in Modeling & Simulation (M&S), the community has focused on generating code or explaining results. We examine the possibility of using LLMs to broaden access to simulations, by enabling non-simulation end-users to ask what-if questions in everyday language. Specifically, we discuss the opportunities and challenges in designing such an end-to-end system, divided into three broad phases. First, assuming the general case in which several simulation models are available, textual queries are mapped to the most relevant model. Second, if a mapping cannot be found, the query can be automatically reformulated and clarifying questions can be generated. Finally, simulation results are produced and contextualized for decision-making. Our vision for such system articulates long-term research opportunities spanning M&S, LLMs, information retrieval, and ethics., Comment: To appear in proceedings of the 2024 Winter Simulation Conference

Published
2024

8. Ultrasound Bone Surface Segmentation for Hip Joint Arthroscopy: Evaluating a Local Phase-Based and a Rigid Object Filtering in a Simulated Environment

Author

de Avila-Armenta, Eduardo, Celaya-Padilla, Jose M., Adamson, Robert B. A., Moreno-Chavez, Gamaliel, Martinez-Torteya, Antonio, Soto-Murillo, Manuel A., Jácome-Cadena, Diana L., Galván-Tejada, Jorge I., Guerrero-Flores, M. Hazael, Cid-Baez, Miguel A., Hartmanis, Juris, Founding Editor, van Leeuwen, Jan, Series Editor, Hutchison, David, Editorial Board Member, Kanade, Takeo, Editorial Board Member, Kittler, Josef, Editorial Board Member, Kleinberg, Jon M., Editorial Board Member, Kobsa, Alfred, Series Editor, Mattern, Friedemann, Editorial Board Member, Mitchell, John C., Editorial Board Member, Naor, Moni, Editorial Board Member, Nierstrasz, Oscar, Series Editor, Pandu Rangan, C., Editorial Board Member, Sudan, Madhu, Series Editor, Terzopoulos, Demetri, Editorial Board Member, Tygar, Doug, Editorial Board Member, Weikum, Gerhard, Series Editor, Vardi, Moshe Y, Series Editor, Goos, Gerhard, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Mezura-Montes, Efrén, editor, Acosta-Mesa, Héctor Gabriel, editor, Carrasco-Ochoa, Jesús Ariel, editor, Martínez-Trinidad, José Francisco, editor, and Olvera-López, José Arturo, editor

Published
2024
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9. Redesign of the Dashboard of a Web Telemetry System for Decision Support

Author

Rivera-Medina, Rubén, Luna-García, Huizilopoztli, Celaya-Padilla, José M., Ordaz-García, Oscar O., Solís-Robles, Roberto, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Ruiz, Pablo H., editor, Agredo-Delgado, Vanessa, editor, and Mon, Alicia, editor

Published
2024
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14. About a dubious proof of a correct result about closed Newton Cotes error formulas

Author

López David J., Padilla Jose A., Ruiz Juan, Tapia Carlos, and Trillo Juan C.

Subjects
newton cotes, closed, integration, error formulas, simpson 3/8, 41a05, 41a55, 65d30, 65d32, Mathematics, QA1-939
Abstract

In this study, we comment about a wrong proof, at least incomplete, of the closed Newton Cotes error formulas for integration in a closed interval [a,b].\left[a,b]. These error formulas appear as an intuitive generalization of the simple proof for the error formula of the trapezoidal rule, and their proofs present one controversial step, which converts the proofs in mischievous, or at least, this step needs a clear clarification that it is not easy to derive. The correct proof of such formulas comes from a technique based on the Peano kernel.

Published
2023
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16. A Bayesian Approach of Predicting the Movement of Internally Displaced Persons

Author

Domson, Obed, Padilla, Jose J., Song, Guohui, Frydenlund, Erika, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Thomson, Robert, editor, Al-khateeb, Samer, editor, Burger, Annetta, editor, Park, Patrick, editor, and A. Pyke, Aryn, editor

Published
2023
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17. Assessing Media’s Representation of Frustration Towards Venezuelan Migrants in Colombia

Author

Llinas, Brian, Huseynli, Guljannat, Frydenlund, Erika, Palacio, Katherine, Llinas, Humberto, Padilla, Jose J., Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Thomson, Robert, editor, Al-khateeb, Samer, editor, Burger, Annetta, editor, Park, Patrick, editor, and A. Pyke, Aryn, editor

Published
2023
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18. Convolutional Neural Network for Monkeypox Detection

Author

Alcalá-Rmz, Vanessa, Villagrana-Bañuelos, Karen E., Celaya-Padilla, José M., Galván-Tejada, Jorge I., Gamboa-Rosales, Hamurabi, Galván-Tejada, Carlos E., Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Bravo, José, editor, Ochoa, Sergio, editor, and Favela, Jesús, editor

Published
2023
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19. Comparison of Three Supervised Machine Learning Classification Methods for the Diagnosis of PD

Author

Villagrana-Bañuelos, Ricardo, Villagrana-Bañuelos, Karen E., Murillo, Manuel A. Soto, Galván-Tejada, Carlos Eric, Celaya-Padilla, José María, Galván-Tejada, Jorge Issac, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Bravo, José, editor, Ochoa, Sergio, editor, and Favela, Jesús, editor

Published
2023
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20. Towards Esophagitis and Barret’s Esophagus Endoscopic Images Classification: An Approach with Deep Learning Techniques

Author

Villagrana-Bañuelos, Karen E., Alcalá-Rmz, Vanessa, Celaya-Padilla, José M., Galván-Tejada, Jorge I., Gamboa-Rosales, Hamurabi, Galván-Tejada, Carlos E., Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Bravo, José, editor, Ochoa, Sergio, editor, and Favela, Jesús, editor

Published
2023
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23. Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes.

Author

Aylward, Anthony, Okino, Mei-Lin, Benaglio, Paola, Chiou, Joshua, Beebe, Elisha, Padilla, Jose Andres, Diep, Sharlene, and Gaulton, Kyle J

Subjects
Developmental Biology, Genetics
Abstract

Glucocorticoids are key regulators of glucose homeostasis and pancreatic islet function, but the gene regulatory programs driving responses to glucocorticoid signaling in islets and the contribution of these programs to diabetes risk are unknown. In this study we used ATAC-seq and RNA-seq to map chromatin accessibility and gene expression from eleven primary human islet samples cultured in vitro with the glucocorticoid dexamethasone at multiple doses and durations. We identified thousands of accessible chromatin sites and genes with significant changes in activity in response to glucocorticoids. Chromatin sites up-regulated in glucocorticoid signaling were prominently enriched for glucocorticoid receptor binding sites and up-regulated genes were enriched for ion transport and lipid metabolism, whereas down-regulated chromatin sites and genes were enriched for inflammatory, stress response and proliferative processes. Genetic variants associated with glucose levels and T2D risk were enriched in glucocorticoid-responsive chromatin sites, including fine-mapped variants at 51 known signals. Among fine-mapped variants in glucocorticoid-responsive chromatin, a likely casual variant at the 2p21 locus had glucocorticoid-dependent allelic effects on beta cell enhancer activity and affected SIX2 and SIX3 expression. Our results provide a comprehensive map of islet regulatory programs in response to glucocorticoids through which we uncover a role for islet glucocorticoid signaling in mediating genetic risk of T2D.

Published
2021

32. Impact of genetic structural variants in factor XI deficiency: identification, accurate characterization, and inferred mechanism by long-read sequencing

Author

de la Morena-Barrio, Belén, Palomo, Ángeles, Padilla, José, Martín-Fernández, Laura, Rojo-Carrillo, Juan José, Cifuentes, Rosa, Bravo-Pérez, Carlos, Garrido-Rodríguez, Pedro, Miñano, Antonia, Rubio, Ana María, Pagán, Javier, Llamas, María, Vicente, Vicente, Vidal, Francisco, Lozano, María Luisa, Corral, Javier, and de la Morena-Barrio, María Eugenia

Published
2023
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36. Driver Identification Using Machine Learning and Motor Activity as Data Source

Author

Espino-Salinas, Carlos H., Luna-García, Huizilopoztli, Celaya-Padilla, José M., Morgan-Benita, Jorge A., Sarmiento, Wilson J., Gamboa-Rosales, Hamurabi, Galván-Tejada, Jorge I., Galván-Tejada, Carlos E., Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Agredo-Delgado, Vanessa, editor, Ruiz, Pablo H., editor, and Correa-Madrigal, Omar, editor

Published
2022
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37. Archaeological and Geophysical Evidence of a High-Energy Marine Event at the Phoenician Site of Cerro del Villar (Malaga, Spain)

Author

Álvarez-Martí-Aguilar, Manuel, Suárez-Padilla, José, Aubet, Mª Eugenia, Machuca Prieto, Francisco, Martín-Casado, Juan Manuel, Feist, Lisa, Val-Peón, Cristina, Reicherter, Klaus, Wagner, Günther A., Series Editor, Miller, Christopher E., Series Editor, Schutkowski, Holger, Series Editor, Álvarez-Martí-Aguilar, Manuel, editor, and Machuca Prieto, Francisco, editor

Published
2022
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40. Two SERPINC1 variants affecting N-glycosylation of Asn224 cause severe thrombophilia not detected by functional assays

Author

de la Morena-Barrio, Maria Eugenia, Suchon, Pierre, Jacobsen, Eva Marie, Iversen, Nina, Miñano, Antonia, de la Morena-Barrio, Belén, Bravo-Pérez, Carlos, Padilla, Jose, Cifuentes, Rosa, Asenjo, Susana, Deleuze, Jean François, Trégouët, David Alexandre, Lozano, Maria Luisa, Vicente, Vicente, Sandset, Per Morten, Morange, Pierre Emmanuel, and Corral, Javier

Published
2022
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42. Desktop Application for Water Quality Prediction and Monitoring System Using ISO 9241-210 and Machine Learning Techniques

Author

Guzman-Fernandez, Maximiliano, Luna-García, Huizilopoztli, Collazos, Cesar A., Sarmiento, Wilson J., Galvan-Tejada, Jorge I., Gamboa-Rosales, Hamurabi, Galvan-Tejada, Carlos E., Celaya-Padilla, Jose M., Zambrano-de la Torre, Misael, Lara-Cisneros, J. Guadalupe, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Ruiz, Pablo H., editor, Agredo-Delgado, Vanessa, editor, and Kawamoto, André Luiz Satoshi, editor

Published
2021
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44. Network Structures and Humanitarian Need

Author

Clark, Mackenzie, Frydenlund, Erika, Padilla, Jose J., Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Thomson, Robert, editor, Hussain, Muhammad Nihal, editor, Dancy, Christopher, editor, and Pyke, Aryn, editor

Published
2021
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45. The Integrated Game Transformation Framework and Cyberwar: What 2×2 Games Tell Us About Cyberattacks

Author

Fretz, Alexander L., Padilla, Jose J., Frydenlund, Erika F., Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Thomson, Robert, editor, Hussain, Muhammad Nihal, editor, Dancy, Christopher, editor, and Pyke, Aryn, editor

Published
2021
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46. An Analysis of Global News Coverage of Refugees Using a Big Data Approach

Author

Yesilbas, Veysel, Padilla, Jose J., Frydenlund, Erika, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Thomson, Robert, editor, Hussain, Muhammad Nihal, editor, Dancy, Christopher, editor, and Pyke, Aryn, editor

Published
2021
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47. The Phoenician diaspora in the westernmost Mediterranean: recent discoveries

Author

Suarez-Padilla, Jose, Jimenez-Jaimez, Victor, and Caro, Jose L.

Subjects
Archaeology -- Analysis, Anthropology/archeology/folklore
Abstract

Important discoveries over the past 15 years in the coastal area between Huelva and Malaga in Spain have illuminated the beginnings of the eighth-century BC Phoenician diaspora into the Western Mediterranean. Here, the authors combine Bayesian modelling of recently published radiocarbon dates with the latest archaeological data to investigate the Phoenician presence in southern Iberia. Their assessment of its significance for the Late Bronze and Early Iron Ages in the Western Mediterranean contributes not only to understanding the integration of the Phoenicians into local communities, but also to apprehending the mechanisms of colonisation and pre-colonial situations elsewhere in protohistoric Europe and other world contexts. Keywords: Mediterranean, Spain, Bronze Age, Iron Age, Phoenicians, colonialism, Introduction In the early first millennium BC, the Late Bronze Age communities of southern Iberia occupied hilltop settlements that were often fortified. Their houses were sometimes large, frequently oval in [...]

Published
2021
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