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23 results on '"Padhan, Kartika"'

1. The IBEX Knowledge-Base: Achieving more together with open science

Author

Radtke, Andrea J., Anidi, Ifeanyichukwu, Arakkal, Leanne, Arroyo-Mejias, Armando, Beuschel, Rebecca T., Borner, Katy, Chu, Colin J., Clark, Beatrice, Clatworthy, Menna R., Colautti, Jake, Croteau, Joshua, Denha, Saven, Dever, Rose, Dutra, Walderez O., Fritzsche, Sonja, Fullam, Spencer, Gerner, Michael Y., Gola, Anita, Gollob, Kenneth J., Hernandez, Jonathan M., Hor, Jyh Liang, Ichise, Hiroshi, Jing, Zhixin, Jonigk, Danny, Kandov, Evelyn, Kastenmueller, Wolfgang, Koenig, Joshua F. E., Kothurkar, Aanandita, Kreins, Alexandra Y., Lamborn, Ian, Lin, Yuri, Morais, Katia Luciano Pereira, Lunich, Aleksandra, Luz, Jean C. S., MacDonald, Ryan B., Makranz, Chen, Maltez, Vivien I., Moriaty, Ryan V., Ocampo-Godinez, Juan M., Olyntho, Vitoria M., Padhan, Kartika, Remmert, Kirsten, Richoz, Nathan, Schrom, Edward C., Shang, Wanjing, Shi, Lihong, Shih, Rochelle M., Speranza, Emily, Stierli, Salome, Teichmann, Sarah A., Veres, Tibor Z., Vierhout, Megan, Wachter, Brianna T., Wade-Vallance, Adam K., Williams, Margaret, Zangger, Nathan, Germain, Ronald N., and Yaniv, Ziv

Subjects
Quantitative Biology - Tissues and Organs
Abstract

Iterative Bleaching Extends multipleXity (IBEX) is a versatile method for highly multiplexed imaging of diverse tissues. Based on open science principles, we created the IBEX Knowledge-Base, a resource for reagents, protocols and more, to empower innovation., Comment: 8 pages, 1 figure, 9 references

Published
2024

3. Acquisition of optimal TFH cell function is defined by specific molecular, positional, and TCR dynamic signatures

Author

Padhan, Kartika, Moysi, Eirini, Noto, Alessandra, Chassiakos, Alexander, Ghneim, Khader, Perra, Maria Maddalena, Shah, Sanjana, Papaioannou, Vasilis, Fabozzi, Giulia, Ambrozak, David R., Poultsidi, Antigoni, Ioannou, Maria, Fenwick, Craig, Darko, Samuel, Douek, Daniel C., Sekaly, Rafick-Pierre, Pantaleo, Giuseppe, Koup, Richard A., and Petrovas, Constantinos

Published
2021

8. Human follicular CD4 T cell function is defined by specific molecular, positional and TCR dynamic signatures

Author

Padhan, Kartika, primary, Moysi, Eirini, additional, Noto, Alessandra, additional, Chassiakos, Alexander, additional, Ghneim, Khader, additional, Shah, Sanjana, additional, Papaioannou, Vasilis, additional, Fabozzi, Giulia, additional, Ambrozak, David, additional, Poultsidi, Antigoni, additional, Ioannou, Maria, additional, Fenwik, Craig, additional, Darko, Samuel, additional, Douek, Daniel C., additional, Sekaly, Rafick-Pierre, additional, Pantaleo, Giuseppe, additional, Koup, Richard A., additional, and Petrovas, Constantinos, additional

Published
2020
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10. Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence

Author

Pino, Maria, primary, Paganini, Sara, additional, Deleage, Claire, additional, Padhan, Kartika, additional, Harper, Justin L., additional, King, Colin T., additional, Micci, Luca, additional, Cervasi, Barbara, additional, Mudd, Joseph C., additional, Gill, Kiran P., additional, Jean, Sherrie M., additional, Easley, Kirk, additional, Silvestri, Guido, additional, Estes, Jacob D., additional, Petrovas, Constantinos, additional, Lederman, Michael M., additional, and Paiardini, Mirko, additional

Published
2019
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11. Star nanoparticles delivering HIV-1 peptide minimal immunogens elicit near-native envelope antibody responses in nonhuman primates

Author

Francica, Joseph R., primary, Laga, Richard, additional, Lynn, Geoffrey M., additional, Mužíková, Gabriela, additional, Androvič, Ladislav, additional, Aussedat, Baptiste, additional, Walkowicz, William E., additional, Padhan, Kartika, additional, Ramirez-Valdez, Ramiro Andrei, additional, Parks, Robert, additional, Schmidt, Stephen D., additional, Flynn, Barbara J., additional, Tsybovsky, Yaroslav, additional, Stewart-Jones, Guillaume B. E., additional, Saunders, Kevin O., additional, Baharom, Faezzah, additional, Petrovas, Constantinos, additional, Haynes, Barton F., additional, and Seder, Robert A., additional

Published
2019
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13. Infection with non-CD4 tropic variant of SIVmac239 accelerates the formation of mature germinal center reactions and elicits antigen specific B cell responses

Author

Dimopoulos, Yiannis Petros, primary, Padhan, Kartika, additional, Moysi, Eirini, additional, Swanstrom, Adrienne, additional, Lifson, Jeffrey D, additional, LaBranche, Celia, additional, Blaire, Robert, additional, Aye, Pyone, additional, Schiro, Faith, additional, Lackner, Andrew, additional, Koup, Richard, additional, Petrovas, Constantinos, additional, and Hoxie, Jim, additional

Published
2017
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15. TCR Microclusters Preexist and Contain Molecules Necessary for TCR Signal Transduction 1

Author

Crites, Travis J, Padhan, Kartika, Muller, James, Krogsgaard, Michelle, Gudla, Prabhakar R., Lockett, Stephen J., and Varma, Rajat

Subjects
Mice, Knockout, Mice, Membrane Microdomains, T-Lymphocytes, Receptors, Antigen, T-Cell, Animals, Leukocyte Common Antigens, hemic and immune systems, chemical and pharmacologic phenomena, Article, Signal Transduction
Abstract

TCR-dependent signaling events have been observed to occur in TCR microclusters. We found that some TCR microclusters are present in unstimulated murine T cells, indicating that the mechanisms leading to microcluster formation do not require ligand binding. These pre-existing microclusters increase in absolute number following engagement by low-potency ligands. This increase is accompanied by an increase in cell spreading, with the result that the density of TCR microclusters on the surface of the T cell is not a strong function of ligand potency. In characterizing their composition, we observed a constant number of TCRs in a microcluster, constitutive exclusion of the phosphatase CD45, and preassociation with the signaling adapters linker for activation of T cells and growth factor receptor-bound protein 2. The existence of TCR microclusters prior to ligand binding in a state that is conducive for the initiation of downstream signaling could explain, in part, the rapid kinetics with which TCR signal transduction occurs.

Published
2014

23. The IBEX Knowledge-Base: Achieving more together with open science.

Author

Radtke AJ, Anidi I, Arakkal L, Arroyo-Mejias A, Beuschel RT, Börner K, Chu CJ, Clark B, Clatworthy MR, Colautti J, Croteau J, Denha S, Dever R, Dutra WO, Fritzsche S, Fullam S, Gerner MY, Gola A, Gollob KJ, Hernandez JM, Hor JL, Ichise H, Jing Z, Jonigk D, Kandov E, Kastenmüller W, Koenig JFE, Kothurkar A, Kreins AY, Lamborn I, Lin Y, Luciano Pereira Morais K, Lunich A, Luz JCS, MacDonald RB, Makranz C, Maltez VI, Moriaty RV, Ocampo-Godinez JM, Olyntho VM, Padhan K, Remmert K, Richoz N, Schrom EC, Shang W, Shi L, Shih RM, Speranza E, Stierli S, Teichmann SA, Veres TZ, Vierhout M, Wachter BT, Wade-Vallance AK, Williams M, Zangger N, Germain RN, and Yaniv Z

Abstract

Iterative Bleaching Extends multipleXity (IBEX) is a versatile method for highly multiplexed imaging of diverse tissues. Based on open science principles, we created the IBEX Knowledge-Base, a resource for reagents, protocols and more, to empower innovation., Competing Interests: Competing interests SAT is a remunerated Scientific Advisory Board member of Qiagen, Foresite Labs, OMass Therapeutics, and a consultant and equity holder of TransitionBio and EnsoCell, and a non-executive board director of 10x Genomics, as well as part-time employee of GlaxoSmithKline. JC is an employee and stakeholder of BioLegend (revvity inc.). All other authors declare no competing interests.

Published
2024

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