Search

Your search keyword '"Packer, Richard"' showing total 134 results
Start Over Author "Packer, Richard"
134 results on '"Packer, Richard"'

1. Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Author

Shrine, Nick, Guyatt, Anna L., Erzurumluoglu, A. Mesut, Jackson, Victoria E., Hobbs, Brian D., Melbourne, Carl A., Batini, Chiara, Fawcett, Katherine A., Song, Kijoung, Sakornsakolpat, Phuwanat, Li, Xingnan, Boxall, Ruth, Reeve, Nicola F., Obeidat, Ma’en, Zhao, Jing Hua, Wielscher, Matthias, Weiss, Stefan, Kentistou, Katherine A., Cook, James P., Sun, Benjamin B., Zhou, Jian, Hui, Jennie, Karrasch, Stefan, Imboden, Medea, Harris, Sarah E., Marten, Jonathan, Enroth, Stefan, Kerr, Shona M., Surakka, Ida, Vitart, Veronique, Lehtimäki, Terho, Allen, Richard J., Bakke, Per S., Beaty, Terri H., Bleecker, Eugene R., Bossé, Yohan, Brandsma, Corry-Anke, Chen, Zhengming, Crapo, James D., Danesh, John, DeMeo, Dawn L., Dudbridge, Frank, Ewert, Ralf, Gieger, Christian, Gulsvik, Amund, Hansell, Anna L., Hao, Ke, Hoffman, Joshua D., Hokanson, John E., Homuth, Georg, Joshi, Peter K., Joubert, Philippe, Langenberg, Claudia, Li, Xuan, Li, Liming, Lin, Kuang, Lind, Lars, Locantore, Nicholas, Luan, Jian’an, Mahajan, Anubha, Maranville, Joseph C., Murray, Alison, Nickle, David C., Packer, Richard, Parker, Margaret M., Paynton, Megan L., Porteous, David J., Prokopenko, Dmitry, Qiao, Dandi, Rawal, Rajesh, Runz, Heiko, Sayers, Ian, Sin, Don D., Smith, Blair H., Artigas, María Soler, Sparrow, David, Tal-Singer, Ruth, Timmers, Paul R. H. J., Van den Berge, Maarten, Whittaker, John C., Woodruff, Prescott G., Yerges-Armstrong, Laura M., Troyanskaya, Olga G., Raitakari, Olli T., Kähönen, Mika, Polašek, Ozren, Gyllensten, Ulf, Rudan, Igor, Deary, Ian J., Probst-Hensch, Nicole M., Schulz, Holger, James, Alan L., Wilson, James F., Stubbe, Beate, Zeggini, Eleftheria, Jarvelin, Marjo-Riitta, Wareham, Nick, Silverman, Edwin K., Hayward, Caroline, Morris, Andrew P., Butterworth, Adam S., Scott, Robert A., Walters, Robin G., Meyers, Deborah A., Cho, Michael H., Strachan, David P., Hall, Ian P., Tobin, Martin D., and Wain, Louise V.

Published
2024
Full Text
View/download PDF

2. Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease

Author

Williams, Alexander T., Chen, Jing, Coley, Kayesha, Batini, Chiara, Izquierdo, Abril, Packer, Richard, Abner, Erik, Kanoni, Stavroula, Shepherd, David J., Free, Robert C., Hollox, Edward J., Brunskill, Nigel J., Ntalla, Ioanna, Reeve, Nicola, Brightling, Christopher E., Venn, Laura, Adams, Emma, Bee, Catherine, Wallace, Susan E., Pareek, Manish, Hansell, Anna L., Esko, Tõnu, Stow, Daniel, Jacobs, Benjamin M., van Heel, David A., Hennah, William, Rao, Balasubramanya S., Dudbridge, Frank, Wain, Louise V., Shrine, Nick, Tobin, Martin D., and John, Catherine

Published
2023
Full Text
View/download PDF

3. SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues

Author

D’Antonio, Matteo, Nguyen, Jennifer P, Arthur, Timothy D, Matsui, Hiroko, Neale, Benjamin M, Daly, Mark, Ganna, Andrea, Stevens, Christine, Pathak, Gita A, Andrews, Shea J, Kanai, Masahiro, Cordioli, Mattia, Karjalainen, Juha, Polimanti, Renato, Pirinen, Matti, Harerimana, Nadia, Veerapen, Kumar, Wolford, Brooke, Nguyen, Huy, Solomonson, Matthew, Liao, Rachel G, Chwialkowska, Karolina, Trankiem, Amy, Balaconis, Mary K, Hayward, Caroline, Richmond, Anne, Campbell, Archie, Morris, Marcela, Fawns-Ritchie, Chloe, Glessner, Joseph T, Shaw, Douglas M, Chang, Xiao, Polikowski, Hannah, Lauren, E, Chen, Hung-Hsin, Wanying, Zhu, Hakonarson, Hakon, Porteous, David J, Below, Jennifer, North, Kari, McCormick, Joseph B, Timmers, Paul RHJ, Wilson, James F, Tenesa, Albert, D’Mellow, Kenton, Kerr, Shona M, Niemi, Mari EK, Nkambul, Lindokuhle, von Hohenstaufen, Kathrin Aprile, Sobh, Ali, Eltoukhy, Madonna M, Yassen, Amr M, Hegazy, Mohamed AF, Okasha, Kamal, Eid, Mohammed A, Moahmed, Hanteera S, Shahin, Doaa, El-Sherbiny, Yasser M, Elhadidy, Tamer A, Elghafar, Mohamed S Abd, El-Jawhari, Jehan J, Mohamed, Attia AS, Elnagdy, Marwa H, Samir, Amr, Abdel-Aziz, Mahmoud, Khafaga, Walid T, El-Lawaty, Walaa M, Torky, Mohamed S, El-shanshory, Mohamed R, Batini, Chiara, Lee, Paul H, Shrine, Nick, Williams, Alexander T, Tobin, Martin D, Guyatt, Anna L, John, Catherine, Packer, Richard J, Ali, Altaf, Free, Robert C, Wang, Xueyang, Wain, Louise V, Hollox, Edward J, Venn, Laura D, Bee, Catherine E, Adams, Emma L, Niavarani, Ahmadreza, Sharififard, Bahareh, Aliannejad, Rasoul, Amirsavadkouhi, Ali, and Naderpour, Zeinab

Subjects
Biological Sciences, Genetics, Infectious Diseases, Human Genome, Coronaviruses Disparities and At-Risk Populations, Coronaviruses, Emerging Infectious Diseases, Lung, Biotechnology, 2.1 Biological and endogenous factors, Good Health and Well Being, COVID-19, Chromosome Mapping, Computational Biology, Databases, Genetic, Ethnicity, Gene Expression, Gene Expression Profiling, Genetic Predisposition to Disease, Genetic Variation, Genome-Wide Association Study, Humans, Organ Specificity, Polymorphism, Single Nucleotide, Quantitative Trait Loci, SARS-CoV-2, Severity of Illness Index, Transcriptome, COVID-19 Host Genetics Initiative, GWAS, colocalization, eQTL, Biochemistry and Cell Biology, Medical Physiology, Biological sciences
Abstract

Variability in SARS-CoV-2 susceptibility and COVID-19 disease severity between individuals is partly due to genetic factors. Here, we identify 4 genomic loci with suggestive associations for SARS-CoV-2 susceptibility and 19 for COVID-19 disease severity. Four of these 23 loci likely have an ethnicity-specific component. Genome-wide association study (GWAS) signals in 11 loci colocalize with expression quantitative trait loci (eQTLs) associated with the expression of 20 genes in 62 tissues/cell types (range: 1:43 tissues/gene), including lung, brain, heart, muscle, and skin as well as the digestive system and immune system. We perform genetic fine mapping to compute 99% credible SNP sets, which identify 10 GWAS loci that have eight or fewer SNPs in the credible set, including three loci with one single likely causal SNP. Our study suggests that the diverse symptoms and disease severity of COVID-19 observed between individuals is associated with variants across the genome, affecting gene expression levels in a wide variety of tissue types.

Published
2021

4. Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

Author

Shrine, Nick, Izquierdo, Abril G., Chen, Jing, Packer, Richard, Hall, Robert J., Guyatt, Anna L., Batini, Chiara, Thompson, Rebecca J., Pavuluri, Chandan, Malik, Vidhi, Hobbs, Brian D., Moll, Matthew, Kim, Wonji, Tal-Singer, Ruth, Bakke, Per, Fawcett, Katherine A., John, Catherine, Coley, Kayesha, Piga, Noemi Nicole, Pozarickij, Alfred, Lin, Kuang, Millwood, Iona Y., Chen, Zhengming, Li, Liming, Wijnant, Sara R. A., Lahousse, Lies, Brusselle, Guy, Uitterlinden, Andre G., Manichaikul, Ani, Oelsner, Elizabeth C., Rich, Stephen S., Barr, R. Graham, Kerr, Shona M., Vitart, Veronique, Brown, Michael R., Wielscher, Matthias, Imboden, Medea, Jeong, Ayoung, Bartz, Traci M., Gharib, Sina A., Flexeder, Claudia, Karrasch, Stefan, Gieger, Christian, Peters, Annette, Stubbe, Beate, Hu, Xiaowei, Ortega, Victor E., Meyers, Deborah A., Bleecker, Eugene R., Gabriel, Stacey B., Gupta, Namrata, Smith, Albert Vernon, Luan, Jian’an, Zhao, Jing-Hua, Hansen, Ailin F., Langhammer, Arnulf, Willer, Cristen, Bhatta, Laxmi, Porteous, David, Smith, Blair H., Campbell, Archie, Sofer, Tamar, Lee, Jiwon, Daviglus, Martha L., Yu, Bing, Lim, Elise, Xu, Hanfei, O’Connor, George T., Thareja, Gaurav, Albagha, Omar M. E., Suhre, Karsten, Granell, Raquel, Faquih, Tariq O., Hiemstra, Pieter S., Slats, Annelies M., Mullin, Benjamin H., Hui, Jennie, James, Alan, Beilby, John, Patasova, Karina, Hysi, Pirro, Koskela, Jukka T., Wyss, Annah B., Jin, Jianping, Sikdar, Sinjini, Lee, Mikyeong, May-Wilson, Sebastian, Pirastu, Nicola, Kentistou, Katherine A., Joshi, Peter K., Timmers, Paul R. H. J., Williams, Alexander T., Free, Robert C., Wang, Xueyang, Morrison, John L., Gilliland, Frank D., Chen, Zhanghua, Wang, Carol A., Foong, Rachel E., Harris, Sarah E., Taylor, Adele, Redmond, Paul, Cook, James P., Mahajan, Anubha, Lind, Lars, Palviainen, Teemu, Lehtimäki, Terho, Raitakari, Olli T., Kaprio, Jaakko, Rantanen, Taina, Pietiläinen, Kirsi H., Cox, Simon R., Pennell, Craig E., Hall, Graham L., Gauderman, W. James, Brightling, Chris, Wilson, James F., Vasankari, Tuula, Laitinen, Tarja, Salomaa, Veikko, Mook-Kanamori, Dennis O., Timpson, Nicholas J., Zeggini, Eleftheria, Dupuis, Josée, Hayward, Caroline, Brumpton, Ben, Langenberg, Claudia, Weiss, Stefan, Homuth, Georg, Schmidt, Carsten Oliver, Probst-Hensch, Nicole, Jarvelin, Marjo-Riitta, Morrison, Alanna C., Polasek, Ozren, Rudan, Igor, Lee, Joo-Hyeon, Sayers, Ian, Rawlins, Emma L., Dudbridge, Frank, Silverman, Edwin K., Strachan, David P., Walters, Robin G., Morris, Andrew P., London, Stephanie J., Cho, Michael H., Wain, Louise V., Hall, Ian P., and Tobin, Martin D.

Published
2023
Full Text
View/download PDF

5. Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

Author

Shrine, Nick, Izquierdo, Abril G., Chen, Jing, Packer, Richard, Hall, Robert J., Guyatt, Anna L., Batini, Chiara, Thompson, Rebecca J., Pavuluri, Chandan, Malik, Vidhi, Hobbs, Brian D., Moll, Matthew, Kim, Wonji, Tal-Singer, Ruth, Bakke, Per, Fawcett, Katherine A., John, Catherine, Coley, Kayesha, Piga, Noemi Nicole, Pozarickij, Alfred, Lin, Kuang, Millwood, Iona Y., Chen, Zhengming, Li, Liming, Wijnant, Sara R. A., Lahousse, Lies, Brusselle, Guy, Uitterlinden, Andre G., Manichaikul, Ani, Oelsner, Elizabeth C., Rich, Stephen S., Barr, R. Graham, Kerr, Shona M., Vitart, Veronique, Brown, Michael R., Wielscher, Matthias, Imboden, Medea, Jeong, Ayoung, Bartz, Traci M., Gharib, Sina A., Flexeder, Claudia, Karrasch, Stefan, Gieger, Christian, Peters, Annette, Stubbe, Beate, Hu, Xiaowei, Ortega, Victor E., Meyers, Deborah A., Bleecker, Eugene R., Gabriel, Stacey B., Gupta, Namrata, Smith, Albert Vernon, Luan, Jian’an, Zhao, Jing-Hua, Hansen, Ailin F., Langhammer, Arnulf, Willer, Cristen, Bhatta, Laxmi, Porteous, David, Smith, Blair H., Campbell, Archie, Sofer, Tamar, Lee, Jiwon, Daviglus, Martha L., Yu, Bing, Lim, Elise, Xu, Hanfei, O’Connor, George T., Thareja, Gaurav, Albagha, Omar M. E., Suhre, Karsten, Granell, Raquel, Faquih, Tariq O., Hiemstra, Pieter S., Slats, Annelies M., Mullin, Benjamin H., Hui, Jennie, James, Alan, Beilby, John, Patasova, Karina, Hysi, Pirro, Koskela, Jukka T., Wyss, Annah B., Jin, Jianping, Sikdar, Sinjini, Lee, Mikyeong, May-Wilson, Sebastian, Pirastu, Nicola, Kentistou, Katherine A., Joshi, Peter K., Timmers, Paul R. H. J., Williams, Alexander T., Free, Robert C., Wang, Xueyang, Morrison, John L., Gilliland, Frank D., Chen, Zhanghua, Wang, Carol A., Foong, Rachel E., Harris, Sarah E., Taylor, Adele, Redmond, Paul, Cook, James P., Mahajan, Anubha, Lind, Lars, Palviainen, Teemu, Lehtimäki, Terho, Raitakari, Olli T., Kaprio, Jaakko, Rantanen, Taina, Pietiläinen, Kirsi H., Cox, Simon R., Pennell, Craig E., Hall, Graham L., Gauderman, W. James, Brightling, Chris, Wilson, James F., Vasankari, Tuula, Laitinen, Tarja, Salomaa, Veikko, Mook-Kanamori, Dennis O., Timpson, Nicholas J., Zeggini, Eleftheria, Dupuis, Josée, Hayward, Caroline, Brumpton, Ben, Langenberg, Claudia, Weiss, Stefan, Homuth, Georg, Schmidt, Carsten Oliver, Probst-Hensch, Nicole, Jarvelin, Marjo-Riitta, Morrison, Alanna C., Polasek, Ozren, Rudan, Igor, Lee, Joo-Hyeon, Sayers, Ian, Rawlins, Emma L., Dudbridge, Frank, Silverman, Edwin K., Strachan, David P., Walters, Robin G., Morris, Andrew P., London, Stephanie J., Cho, Michael H., Wain, Louise V., Hall, Ian P., and Tobin, Martin D.

Published
2023
Full Text
View/download PDF

6. Genetic Associations and Architecture of Asthma-COPD Overlap

Author

John, Catherine, Guyatt, Anna L., Shrine, Nick, Packer, Richard, Olafsdottir, Thorunn A., Liu, Jiangyuan, Hayden, Lystra P., Chu, Su H., Koskela, Jukka T., Luan, Jian’an, Li, Xingnan, Terzikhan, Natalie, Xu, Hanfei, Bartz, Traci M., Petersen, Hans, Leng, Shuguang, Belinsky, Steven A., Cepelis, Aivaras, Hernández Cordero, Ana I., Obeidat, Ma’en, Thorleifsson, Gudmar, Meyers, Deborah A., Bleecker, Eugene R., Sakoda, Lori C., Iribarren, Carlos, Tesfaigzi, Yohannes, Gharib, Sina A., Dupuis, Josée, Brusselle, Guy, Lahousse, Lies, Ortega, Victor E., Jonsdottir, Ingileif, Sin, Don D., Bossé, Yohan, van den Berge, Maarten, Nickle, David, Quint, Jennifer K., Sayers, Ian, Hall, Ian P., Langenberg, Claudia, Ripatti, Samuli, Laitinen, Tarja, Wu, Ann C., Lasky-Su, Jessica, Bakke, Per, Gulsvik, Amund, Hersh, Craig P., Hayward, Caroline, Langhammer, Arnulf, Brumpton, Ben, Stefansson, Kari, Cho, Michael H., Wain, Louise V., and Tobin, Martin D.

Published
2022
Full Text
View/download PDF

7. Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study

Author

Shrine, Nick, Portelli, Michael A, John, Catherine, Soler Artigas, María, Bennett, Neil, Hall, Robert, Lewis, Jon, Henry, Amanda P, Billington, Charlotte K, Ahmad, Azaz, Packer, Richard J, Shaw, Dominick, Pogson, Zara E K, Fogarty, Andrew, McKeever, Tricia M, Singapuri, Amisha, Heaney, Liam G, Mansur, Adel H, Chaudhuri, Rekha, Thomson, Neil C, Holloway, John W, Lockett, Gabrielle A, Howarth, Peter H, Djukanovic, Ratko, Hankinson, Jenny, Niven, Robert, Simpson, Angela, Chung, Kian Fan, Sterk, Peter J, Blakey, John D, Adcock, Ian M, Hu, Sile, Guo, Yike, Obeidat, Maen, Sin, Don D, van den Berge, Maarten, Nickle, David C, Bossé, Yohan, Tobin, Martin D, Hall, Ian P, Brightling, Christopher E, Wain, Louise V, and Sayers, Ian

Published
2019
Full Text
View/download PDF

10. New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Author

Shrine, Nick, Guyatt, Anna L., Erzurumluoglu, A. Mesut, Jackson, Victoria E., Hobbs, Brian D., Melbourne, Carl A., Batini, Chiara, Fawcett, Katherine A., Song, Kijoung, Sakornsakolpat, Phuwanat, Li, Xingnan, Boxall, Ruth, Reeve, Nicola F., Obeidat, Ma’en, Zhao, Jing Hua, Wielscher, Matthias, Weiss, Stefan, Kentistou, Katherine A., Cook, James P., Sun, Benjamin B., Zhou, Jian, Hui, Jennie, Karrasch, Stefan, Imboden, Medea, Harris, Sarah E, Marten, Jonathan, Enroth, Stefan, Kerr, Shona M., Surakka, Ida, Vitart, Veronique, Lehtimäki, Terho, Allen, Richard J., Bakke, Per S., Beaty, Terri H., Bleecker, Eugene R., Bossé, Yohan, Brandsma, Corry-Anke, Chen, Zhengming, Crapo, James D., Danesh, John, DeMeo, Dawn L., Dudbridge, Frank, Ewert, Ralf, Gieger, Christian, Gulsvik, Amund, Hansell, Anna L., Hao, Ke, Hoffman, Joshua D., Hokanson, John E., Homuth, Georg, Joshi, Peter K., Joubert, Philippe, Langenberg, Claudia, Li, Xuan, Li, Liming, Lin, Kuang, Lind, Lars, Locantore, Nicholas, Luan, Jian’an, Mahajan, Anubha, Maranville, Joseph C., Murray, Alison, Nickle, David C., Packer, Richard, Parker, Margaret M., Paynton, Megan L., Porteous, David J., Prokopenko, Dmitry, Qiao, Dandi, Rawal, Rajesh, Runz, Heiko, Sayers, Ian, Sin, Don D, Smith, Blair H, Soler Artigas, María, Sparrow, David, Tal-Singer, Ruth, Timmers, Paul R. H. J., Van den Berge, Maarten, Whittaker, John C., Woodruff, Prescott G., Yerges-Armstrong, Laura M., Troyanskaya, Olga G., Raitakari, Olli T., Kähönen, Mika, Polašek, Ozren, Gyllensten, Ulf, Rudan, Igor, Deary, Ian J., Probst-Hensch, Nicole M., Schulz, Holger, James, Alan L, Wilson, James F., Stubbe, Beate, Zeggini, Eleftheria, Jarvelin, Marjo-Riitta, Wareham, Nick, Silverman, Edwin K., Hayward, Caroline, Morris, Andrew P., Butterworth, Adam S., Scott, Robert A., Walters, Robin G., Meyers, Deborah A., Cho, Michael H., Strachan, David P., Hall, Ian P., Tobin, Martin D., and Wain, Louise V.

Published
2019
Full Text
View/download PDF

11. Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection

Author

Packer, Richard J., primary, Shrine, Nick, additional, Hall, Robert, additional, Melbourne, Carl A., additional, Thompson, Rebecca, additional, Williams, Alex T., additional, Paynton, Megan L., additional, Guyatt, Anna L., additional, Allen, Richard J., additional, Lee, Paul H., additional, John, Catherine, additional, Campbell, Archie, additional, Hayward, Caroline, additional, de Vries, Maaike, additional, Vonk, Judith M., additional, Davitte, Jonathan, additional, Hessel, Edith, additional, Michalovich, David, additional, Betts, Joanna C., additional, Sayers, Ian, additional, Yeo, Astrid, additional, Hall, Ian P., additional, Tobin, Martin D., additional, and Wain, Louise V., additional

Published
2023
Full Text
View/download PDF

12. Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection

Author

Packer, Richard J., Shrine, Nick, Hall, Robert, Melbourne, Carl A., Thompson, Rebecca, Williams, Alex T., Paynton, Megan L., Guyatt, Anna L., Allen, Richard J., Lee, Paul H., John, Catherine, Campbell, Archie, Hayward, Caroline, Vries, Maaike de, Vonk, Judith M., Davitte, Jonathan, Hessel, Edith, Michalovich, David, Betts, Joanna C., Sayers, Ian, Yeo, Astrid, Hall, Ian P., Tobin, Martin D., and Wain, Louise V.

Abstract

BACKGROUND: Chronic sputum production impacts on quality of life and is a feature of many respiratory diseases. Identification of the genetic variants associated with chronic sputum production in a disease agnostic sample could improve understanding of its causes and identify new molecular targets for treatment.METHODS: We conducted a genome-wide association study (GWAS) of chronic sputum production in UK Biobank. Signals meeting genome-wide significance (pFINDINGS: From a GWAS of 9714 cases and 48 471 controls, we identified six novel genome-wide significant signals for chronic sputum production including signals in the Human Leukocyte Antigen (HLA) locus, chromosome 11 mucin locus (containing MUC2, MUC5AC and MUC5B) and the FUT2 locus. The four common variant associations were supported by independent studies with a combined sample size of up to 2,203 cases and 17,627 controls. The mucin locus signal had previously been reported for association with moderate-to-severe asthma. The HLA signal was fine-mapped to an amino-acid change of threonine to arginine (frequency 36.8%) in HLA-DRB1 (HLA-DRB1*03:147). The signal near FUT2 was associated with expression of several genes including FUT2, for which the direction of effect was tissue dependent. Our PheWAS identified a wide range of associations including blood cell traits, liver biomarkers, infections, gastrointestinal and thyroid-associated diseases, and respiratory disease.INTERPRETATION: Novel signals at the FUT2 and mucin loci suggest that mucin fucosylation may be a driver of chronic sputum production even in the absence of diagnosed respiratory disease and provide genetic support for this pathway as a target for therapeutic intervention.

Published
2023

24. DeepPheWAS: an R package for phenotype generation and association analysis for phenome-wide association studies

Author

Packer, Richard J, primary, Williams, Alex T, additional, Hennah, William, additional, Eisenberg, Micaela T, additional, Shrine, Nick, additional, Fawcett, Katherine A, additional, Pearson, Willow, additional, Guyatt, Anna L, additional, Edris, Ahmed, additional, Hollox, Edward J, additional, Marttila, Mikko, additional, Rao, Balasubramanya S, additional, Bratty, John Raymond, additional, Wain, Louise V, additional, Dudbridge, Frank, additional, and Tobin, Martin D, additional

Published
2023
Full Text
View/download PDF

25. Improved data linkage in the Extended Cohort for E-health, Environment and DNA (EXCEED) study through an electronic informed consent (eConsent) and recruitment management system.

Author

Wang, Xueyang, primary, Adams, Emma, additional, Bee, Catherine, additional, Guyatt, Anna, additional, John, Catherine, additional, Packer, Richard, additional, Shepherd, David, additional, Venn, Laura, additional, Tobin, Martin, additional, and Free, Robert, additional

Published
2022
Full Text
View/download PDF

27. Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Author

Shrine, Nick, Guyatt, Anna L., Erzurumluoglu, A. Mesut, Jackson, Victoria E., Hobbs, Brian D., Melbourne, Carl A., Batini, Chiara, Fawcett, Katherine A., Song, Kijoung, Sakornsakolpat, Phuwanat, Li, Xingnan, Boxall, Ruth, Reeve, Nicola F., Obeidat, Ma’en, Zhao, Jing Hua, Wielscher, Matthias, Weiss, Stefan, Kentistou, Katherine A., Cook, James P., Sun, Benjamin B., Zhou, Jian, Hui, Jennie, Karrasch, Stefan, Imboden, Medea, Harris, Sarah E, Marten, Jonathan, Enroth, Stefan, Kerr, Shona M., Surakka, Ida, Vitart, Veronique, Lehtimäki, Terho, Allen, Richard J., Bakke, Per S., Beaty, Terri H., Bleecker, Eugene R., Bossé, Yohan, Brandsma, Corry-Anke, Chen, Zhengming, Crapo, James D., Danesh, John, DeMeo, Dawn L., Dudbridge, Frank, Ewert, Ralf, Gieger, Christian, Gulsvik, Amund, Hansell, Anna L., Hao, Ke, Hoffman, Joshua D., Hokanson, John E., Homuth, Georg, Joshi, Peter K., Joubert, Philippe, Langenberg, Claudia, Li, Xuan, Li, Liming, Lin, Kuang, Lind, Lars, Locantore, Nicholas, Luan, Jian’an, Mahajan, Anubha, Maranville, Joseph C., Murray, Alison, Nickle, David C., Packer, Richard, Parker, Margaret M., Paynton, Megan L., Porteous, David J., Prokopenko, Dmitry, Qiao, Dandi, Rawal, Rajesh, Runz, Heiko, Sayers, Ian, Sin, Don D, Smith, Blair H, Artigas, María Soler, Sparrow, David, Tal-Singer, Ruth, Timmers, Paul R. H. J., Van den Berge, Maarten, Whittaker, John C., Woodruff, Prescott G., Yerges-Armstrong, Laura M., Troyanskaya, Olga G., Raitakari, Olli T., Kähönen, Mika, Polašek, Ozren, Gyllensten, Ulf, Rudan, Igor, Deary, Ian J., Probst-Hensch, Nicole M., Schulz, Holger, James, Alan L, Wilson, James F., Stubbe, Beate, Zeggini, Eleftheria, Jarvelin, Marjo-Riitta, Wareham, Nick, Silverman, Edwin K., Hayward, Caroline, Morris, Andrew P., Butterworth, Adam S., Scott, Robert A., Walters, Robin G., Meyers, Deborah A., Cho, Michael H., Strachan, David P., Hall, Ian P., Tobin, Martin D., and Wain, Louise V.

Published
2019
Full Text
View/download PDF

28. Multi-ancestry genome-wide association study improves resolution of genes, pathways and pleiotropy for lung function and chronic obstructive pulmonary disease

Author

Shrine, Nick, primary, Izquierdo, Abril G, additional, Chen, Jing, additional, Packer, Richard, additional, Hall, Robert J, additional, Guyatt, Anna L, additional, Batini, Chiara, additional, Thompson, Rebecca J, additional, Pavuluri, Chandan, additional, Malik, Vidhi, additional, Hobbs, Brian D, additional, Moll, Matthew, additional, Kim, Wonji, additional, Tal-Singer, Ruth, additional, Bakke, Per, additional, Fawcett, Katherine A, additional, John, Catherine, additional, Coley, Kayesha, additional, Piga, Noemi Nicole, additional, Pozarickij, Alfred, additional, Lin, Kuang, additional, Millwood, Iona Y, additional, Chen, Zhengming, additional, Li, Liming, additional, Wielscher, Sara RA, additional, Lahousse, Lies, additional, Brusselle, Guy, additional, Uitterlinden, Andre G, additional, Manichaikul, Ani, additional, Oelsner, Elizabeth C, additional, Rich, Stephen S, additional, Barr, R. Graham, additional, Kerr, Shona M, additional, Vitart, Veronique, additional, Brown, Michael R, additional, Wielscher, Matthias, additional, Imboden, Medea, additional, Jeong, Ayoung, additional, Bartz, Traci M, additional, Gharib, Sina A, additional, Flexeder, Claudia, additional, Karrasch, Stefan, additional, Gieger, Christian, additional, Peters, Annette, additional, Stubbe, Beate, additional, Hu, Xiaowei, additional, Ortega, Victor E, additional, Meyers, Deborah A, additional, Bleecker, Eugene R, additional, Gabriel, Stacey B, additional, Gupta, Namrata, additional, Smith, Albert Vernon, additional, Luan, Jian’an, additional, Zhao, Jing-Hua, additional, Hansen, Ailin F, additional, Langhammer, Arnulf, additional, Willer, Cristen, additional, Bhatta, Laxmi, additional, Porteous, David, additional, Smith, Blair H, additional, Campbell, Archie, additional, Sofer, Tamar, additional, Lee, Jiwon, additional, Daviglus, Martha L, additional, Yu, Bing, additional, Lim, Elise, additional, Xu, Hanfei, additional, O’Connor, George T, additional, Thareja, Gaurav, additional, E., Omar M, additional, Mbarek, Hamdi, additional, Suhre, Karsten, additional, Granell, Raquel, additional, Faquih, Tariq O, additional, Hiemstra, Pieter S, additional, Slats, Annelies M, additional, Mullin, Benjamin H, additional, Hui, Jennie, additional, James, Alan, additional, Beilby, John, additional, Patasova, Karina, additional, Hysi, Pirro, additional, Koskela, Jukka T, additional, Wyss, Annah B, additional, Jin, Jianping, additional, Sikdar, Sinjini, additional, Lee, Mikyeong, additional, May-Wilson, Sebastian, additional, Pirastu, Nicola, additional, Kentistou, Katherine A, additional, Joshi, Peter K, additional, Timmers, Paul RHJ, additional, Williams, Alexander T, additional, Free, Robert C, additional, Wang, Xueyang, additional, Morrison, John L, additional, Gilliland, Frank D, additional, Chen, Zhanghua, additional, Wang, Carol A, additional, Foong, Rachel E, additional, Harris, Sarah E, additional, Taylor, Adele, additional, Redmond, Paul, additional, Cook, James P, additional, Mahajan, Anubha, additional, Lind, Lars, additional, Palviainen, Teemu, additional, Lehtimäki, Terho, additional, Raitakari, Olli T, additional, Kaprio, Jaakko, additional, Rantanen, Taina, additional, Pietiläinen, Kirsi H, additional, Cox, Simon R, additional, Pennell, Craig E, additional, Hall, Graham L, additional, Gauderman, W. James, additional, Brightling, Chris, additional, Wilson, James F, additional, Vasankari, Tuula, additional, Laitinen, Tarja, additional, Salomaa, Veikko, additional, Mook-Kanamori, Dennis O, additional, Timpson, Nicholas J, additional, Zeggini, Eleftheria, additional, Dupuis, Josée, additional, Hayward, Caroline, additional, Brumpton, Ben, additional, Langenberg, Claudia, additional, Weiss, Stefan, additional, Homuth, Georg, additional, Schmidt, Carsten Oliver, additional, Probst-Hensch, Nicole, additional, Jarvelin, Marjo-Riitta, additional, Morrison, Alanna C, additional, Polasek, Ozren, additional, Rudan, Igor, additional, Lee, Joo-Hyeon, additional, Sayers, Ian, additional, Rawlins, Emma L, additional, Dudbridge, Frank, additional, Silverman, Edwin K, additional, Strachan, David P, additional, Walters, Robin G, additional, Morris, Andrew P, additional, London, Stephanie J, additional, Cho, Michael H, additional, Wain, Louise V, additional, Hall, Ian P, additional, and Tobin, Martin D, additional

Published
2022
Full Text
View/download PDF

29. Extended Cohort for E-health, Environment and DNA (EXCEED) COVID-19 focus

Author

Lee, Paul H., primary, Guyatt, Anna L., additional, John, Catherine, additional, Ali, Altaf, additional, Wang, Xueyang, additional, Williams, Alexander T., additional, Zhao, Bo, additional, Batini, Chiara, additional, Bee, Catherine, additional, Adams, Emma, additional, Melbourne, Carl A., additional, Brightling, Christopher E., additional, Hsu, Ron, additional, Bethea, Jane, additional, Reeve, Nicola, additional, Ntalla, Ioanna, additional, Terry, Sarah, additional, Pareek, Manish, additional, Brunskill, Nigel J., additional, Barwell, Julian, additional, Hollox, Edward J., additional, Miola, Jose, additional, Wallace, Susan E., additional, Shepherd, David J., additional, Packer, Richard, additional, Venn, Laura, additional, Wain, Louise V., additional, Free, Robert C., additional, and Tobin, Martin D., additional

Published
2021
Full Text
View/download PDF

30. Pleiotropic associations of heterozygosity for the SERPINA1 Z allele in the UK Biobank

Author

Fawcett, Katherine A., primary, Song, Kijoung, additional, Qian, Guoqing, additional, Farmaki, Aliki-Eleni, additional, Packer, Richard, additional, John, Catherine, additional, Shrine, Nick, additional, Granell, Raquel, additional, Ring, Sue, additional, Timpson, Nicholas J., additional, Yerges-Armstrong, Laura M., additional, Eastell, Richard, additional, Wain, Louise V., additional, Scott, Robert A., additional, Tobin, Martin D., additional, and Hall, Ian P., additional

Published
2021
Full Text
View/download PDF

31. Promoter Hypermethylation

Author

Pellacani, Davide, primary, Packer, Richard, additional, Frame, Fiona, additional, Oldridge, Emma, additional, Berry, Paul, additional, Labarthe, Marie-Christine, additional, Stower, Michael, additional, Simms, Matthew, additional, Collins, Anne, additional, and Maitland, Norman, additional

Published
2013
Full Text
View/download PDF

32. Pleiotropic effects of heterozygosity for theSERPINA1Z allele in the UK Biobank

Author

Fawcett, Katherine A, primary, Song, Kijoung, additional, Qian, Guoqing, additional, Farmaki, Aliki-Eleni, additional, Packer, Richard, additional, John, Catherine, additional, Shrine, Nick, additional, Granell, Raquel, additional, Ring, Sue, additional, Timpson, Nicholas J, additional, Yerges-Armstrong, Laura M, additional, Eastell, Richard, additional, Wain, Louise V, additional, Scott, Robert A, additional, Tobin, Martin D, additional, and Hall, Ian P, additional

Published
2020
Full Text
View/download PDF

34. Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study

Author

Hall, Robert, Shrine, Nick, Portelli, Michael A., John, Catherine, Bennett, Neil, Lewis, Jon, Henry, Amanda P., Billington, Charlotte K., Ahmad, Azaz, Packer, Richard J., Shaw, Dominick, Pogson, Zara E.K., Fogarty, Andrew, McKeever, Tricia M., Singapuri, Amisha, Heaney, Liam G., Mansur, Adel H., Chaudhuri, Rekha, Thomson, Neil C., Holloway, John W., Lockett, Gabrielle A., Howarth, Peter H., Djukanovic, Ratko, Hankinson, Jenny, Niven, Robert, Simpson, Angela, Fan Chung, Kian, Sterk, Peter J., Blakey, John D., Adcock, Ian M., Hu, Sile, Guo, Yike, Obeidat, Maen, Sin, Don D., van den Berge, Maarten, Nickle, David C., Tobin, Martin D., Hall, Ian P., Brightling, Christopher E., Wain, Louise V., and Sayers, Ian

Abstract

BackgroundFew genetic studies that focus on moderate-to-severe asthma exist. We aimed to identity novel genetic variants associated with moderate-to-severe asthma, see whether previously identified genetic variants for all types of asthma contribute to moderate-to-severe asthma, and provide novel mechanistic insights using expression analyses in patients with asthma.MethodsIn this genome-wide association study, we used a two-stage case-control design. In stage 1, we genotyped patient-level data from two UK cohorts (the Genetics of Asthma Severity and Phenotypes [GASP] initiative and the Unbiased BIOmarkers in PREDiction of respiratory disease outcomes [U-BIOPRED] project) and used data from the UK Biobank to collect patient-level genomic data for cases and controls of European ancestry in a 1:5 ratio. Cases were defined as having moderate-to-severe asthma if they were taking appropriate medication or had been diagnosed by a doctor. Controls were defined as not having asthma, rhinitis, eczema, allergy, emphysema, or chronic bronchitis as diagnosed by a doctor. For stage 2, an independent cohort of cases and controls (1:5) was selected from the UK Biobank only, with no overlap with stage 1 samples. In stage 1 we undertook a genome-wide association study of moderate-to-severe asthma, and in stage 2 we followed up independent variants that reached the significance threshold of p less than 1 × 10−6 in stage 1. We set genome-wide significance at p less than 5 × 10−8. For novel signals, we investigated their effect on all types of asthma (mild, moderate, and severe). For all signals meeting genome-wide significance, we investigated their effect on gene expression in patients with asthma and controls.FindingsWe included 5135 cases and 25 675 controls for stage 1, and 5414 cases and 21 471 controls for stage 2. We identified 24 genome-wide significant signals of association with moderate-to-severe asthma, including several signals in innate or adaptive immune-response genes. Three novel signals were identified: rs10905284 in GATA3 (coded allele A, odds ratio [OR] 0·90, 95% CI 0·88–0·93; p=1·76 × 10−10), rs11603634 in the MUC5AC region (coded allele G, OR 1·09, 1·06–1·12; p=2·32 × 10−8), and rs560026225 near KIAA1109 (coded allele GATT, OR 1·12, 1·08–1·16; p=3·06 × 10−9). The MUC5AC signal was not associated with asthma when analyses included mild asthma. The rs11603634 G allele was associated with increased expression of MUC5AC mRNA in bronchial epithelial brush samples via proxy SNP rs11602802; (p=2·50 × 10−5) and MUC5AC mRNA was increased in bronchial epithelial samples from patients with severe asthma (in two independent analyses, p=0·039 and p=0·022).InterpretationWe found substantial shared genetic architecture between mild and moderate-to-severe asthma. We also report for the first time genetic variants associated with the risk of developing moderate-to-severe asthma that regulate mucin production. Finally, we identify candidate causal genes in these loci and provide increased insight into this difficult to treat population.

Published
2019

36. Corrigendum to: Cohort profile: Extended Cohort for E-health, Environment and DNA (EXCEED)

Author

John, Catherine, primary, Reeve, Nicola F, additional, Free, Robert C, additional, Williams, Alexander T, additional, Ntalla, Ioanna, additional, Farmaki, Aliki-Eleni, additional, Bethea, Jane, additional, Barton, Linda M, additional, Shrine, Nick, additional, Batini, Chiara, additional, Packer, Richard, additional, Terry, Sarah, additional, Hargadon, Beverley, additional, Wang, Qingning, additional, Melbourne, Carl A, additional, Adams, Emma L, additional, Bee, Catherine E, additional, Harrington, Kyla, additional, Miola, José, additional, Brunskill, Nigel J, additional, Brightling, Christopher E, additional, Barwell, Julian, additional, Wallace, Susan E, additional, Hsu, Ron, additional, Shepherd, David J, additional, Hollox, Edward J, additional, Wain, Louise V, additional, and Tobin, Martin D, additional

Published
2019
Full Text
View/download PDF

37. Cohort Profile: Extended Cohort for E-health, Environment and DNA (EXCEED)

Author

John, Catherine, primary, Reeve, Nicola F, additional, Free, Robert C, additional, Williams, Alexander T, additional, Ntalla, Ioanna, additional, Farmaki, Aliki-Eleni, additional, Bethea, Jane, additional, Barton, Linda M, additional, Shrine, Nick, additional, Batini, Chiara, additional, Packer, Richard, additional, Terry, Sarah, additional, Hargadon, Beverley, additional, Wang, Qingning, additional, Melbourne, Carl A, additional, Adams, Emma L, additional, Bee, Catherine E, additional, Harrington, Kyla, additional, Miola, José, additional, Brunskill, Nigel J, additional, Brightling, Christopher E, additional, Barwell, Julian, additional, Wallace, Susan E, additional, Hsu, Ron, additional, Shepherd, David J, additional, Hollox, Edward J, additional, Wain, Louise V, additional, and Tobin, Martin D, additional

Published
2019
Full Text
View/download PDF

38. Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer

Author

Stower Michael J, Labarthe Marie-Christine, Berry Paul A, Oldridge Emma E, Frame Fiona M, Packer Richard J, Pellacani Davide, Simms Matthew S, Collins Anne T, and Maitland Norman J

Subjects
CD133, prostate cancer, cancer stem cells, epigenetic regulation of gene expression, DNA methylation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background Epigenetic control is essential for maintenance of tissue hierarchy and correct differentiation. In cancer, this hierarchical structure is altered and epigenetic control deregulated, but the relationship between these two phenomena is still unclear. CD133 is a marker for adult stem cells in various tissues and tumour types. Stem cell specificity is maintained by tight regulation of CD133 expression at both transcriptional and post-translational levels. In this study we investigated the role of epigenetic regulation of CD133 in epithelial differentiation and cancer. Methods DNA methylation analysis of the CD133 promoter was done by pyrosequencing and methylation specific PCR; qRT-PCR was used to measure CD133 expression and chromatin structure was determined by ChIP. Cells were treated with DNA demethylating agents and HDAC inhibitors. All the experiments were carried out in both cell lines and primary samples. Results We found that CD133 expression is repressed by DNA methylation in the majority of prostate epithelial cell lines examined, where the promoter is heavily CpG hypermethylated, whereas in primary prostate cancer and benign prostatic hyperplasia, low levels of DNA methylation, accompanied by low levels of mRNA, were found. Moreover, differential methylation of CD133 was absent from both benign or malignant CD133+/α2β1integrinhi prostate (stem) cells, when compared to CD133-/α2β1integrinhi (transit amplifying) cells or CD133-/α2β1integrinlow (basal committed) cells, selected from primary epithelial cultures. Condensed chromatin was associated with CD133 downregulation in all of the cell lines, and treatment with HDAC inhibitors resulted in CD133 re-expression in both cell lines and primary samples. Conclusions CD133 is tightly regulated by DNA methylation only in cell lines, where promoter methylation and gene expression inversely correlate. This highlights the crucial choice of cell model systems when studying epigenetic control in cancer biology and stem cell biology. Significantly, in both benign and malignant prostate primary tissues, regulation of CD133 is independent of DNA methylation, but is under the dynamic control of chromatin condensation. This indicates that CD133 expression is not altered in prostate cancer and it is consistent with an important role for CD133 in the maintenance of the hierarchical cell differentiation patterns in cancer.

Published
2011
Full Text
View/download PDF

39. Cohort Profile: Extended Cohort for E-health, Environment and DNA (EXCEED)

Author

John, Catherine, primary, Reeve, Nicola F, additional, Free, Robert C, additional, Williams, Alexander T, additional, Farmaki, Aliki-Eleni, additional, Bethea, Jane, additional, Barton, Linda M, additional, Shrine, Nick, additional, Batini, Chiara, additional, Packer, Richard, additional, Terry, Sarah, additional, Hargadon, Beverley, additional, Wang, Qingning, additional, Melbourne, Carl A, additional, Adams, Emma L, additional, Bee, Catherine E, additional, Harrington, Kyla, additional, Miola, José, additional, Brunskill, Nigel J, additional, Brightling, Christopher E, additional, Barwell, Julian, additional, Wallace, Susan E, additional, Hsu, Ron, additional, Shepherd, David J, additional, Hollox, Edward J, additional, Wain, Louise V, additional, and Tobin, Martin D, additional

Published
2018
Full Text
View/download PDF

40. New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

Author

Shrine, Nick, primary, Guyatt, Anna L, additional, Erzurumluoglu, A Mesut, additional, Jackson, Victoria E, additional, Hobbs, Brian D, additional, Melbourne, Carl, additional, Batini, Chiara, additional, Fawcett, Katherine A, additional, Song, Kijoung, additional, Sakornsakolpat, Phuwanat, additional, Li, Xingnan, additional, Boxall, Ruth, additional, Reeve, Nicola F, additional, Obeidat, Ma’en, additional, Zhao, Jing Hua, additional, Wielscher, Matthias, additional, Society Scientific Group, Understanding, additional, Weiss, Stefan, additional, Kentistou, Katherine A, additional, Cook, James P, additional, Sun, Benjamin B, additional, Zhou, Jian, additional, Hui, Jennie, additional, Karrasch, Stefan, additional, Imboden, Medea, additional, Harris, Sarah E, additional, Marten, Jonathan, additional, Enroth, Stefan, additional, Kerr, Shona M, additional, Surakka, Ida, additional, Vitart, Veronique, additional, Lehtimäki, Terho, additional, Allen, Richard J, additional, Bakke, Per S, additional, Beaty, Terri H, additional, Bleecker, Eugene R, additional, Bossé, Yohan, additional, Brandsma, Corry-Anke, additional, Chen, Zhengming, additional, Crapo, James D, additional, Danesh, John, additional, DeMeo, Dawn L, additional, Dudbridge, Frank, additional, Ewert, Ralf, additional, Gieger, Christian, additional, Gulsvik, Amund, additional, Hansell, Anna L, additional, Hao, Ke, additional, Hoffman, Josh D, additional, Hokanson, John, additional, Homuth, Georg, additional, Joshi, Peter K, additional, Joubert, Philippe, additional, Langenberg, Claudia, additional, Li, Xuan, additional, Li, Liming, additional, Lin, Kuang, additional, Lind, Lars, additional, Locantore, Nick, additional, Luan, Jian’an, additional, Mahajan, Anubha, additional, Maranville, Joseph C, additional, Murray, Alison, additional, Nickle, David C, additional, Packer, Richard, additional, Parker, Margaret M, additional, Paynton, Megan L, additional, Porteous, David, additional, Prokopenko, Dmitry, additional, Qiao, Dandi, additional, Rawal, Rajesh, additional, Runz, Heiko, additional, Sayers, Ian, additional, Sin, Don D, additional, H Smith, Blair, additional, Artigas, María Soler, additional, Sparrow, David, additional, Tal-Singer, Ruth, additional, Timmers, Paul RHJ, additional, Van den Berge, Maarten, additional, Whittaker, John C, additional, Woodruff, Prescott, additional, M Yerges Armstrong, Laura, additional, Troyanskaya, Olga G, additional, Raitakari, Olli T, additional, Kähönen, Mika, additional, Polasek, Ozren, additional, Gyllensten, Ulf, additional, Rudan, Igor, additional, Deary, Ian J, additional, Probst-Hensch, Nicole M, additional, Schulz, Holger, additional, James, Alan L, additional, Wilson, James F, additional, Stubbe, Beate, additional, Zeggini, Eleftheria, additional, Jarvelin, Marjo-Riitta, additional, Wareham, Nick, additional, Silverman, Edwin K, additional, Hayward, Caroline, additional, Morris, Andrew P, additional, Butterworth, Adam S, additional, Scott, Robert A, additional, Walters, Robin G, additional, Meyers, Deborah A, additional, Cho, Michael H, additional, Strachan, David P, additional, Hall, Ian P, additional, Tobin, Martin D, additional, and Wain, Louise V, additional

Published
2018
Full Text
View/download PDF

41. Academic Training

Author

Weisberg, Paul, Packer, Richard A., Weisberg, Roberta S., Bellack, Alan S., editor, Hersen, Michel, editor, Matson, Johnny L., editor, and McCartney, John R., editor

Published
1981
Full Text
View/download PDF

48. DELIUS AND BAX CHORAL MUSIC.

Author

Packer, Richard

Subjects
DELIUS & Bax Choral Music (Music), CARICE Singers (Performer)
Published
2017

Catalog

Books, media, physical & digital resources
See catalog results