163 results on '"Pacheco-Barrios K"'
Search Results
2. Factors influencing clinical trial participation of women with fibromyalgia across the United States: a cross-sectional survey
- Author
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Cardenas-Rojas, A., primary, Pacheco-Barrios, K., additional, Castelo-Branco, L., additional, Gonzalez-Mego, P., additional, Marduy, A., additional, Vásquez-Ávila, K., additional, Caumo, W., additional, and Fregni, F., additional
- Published
- 2024
- Full Text
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3. Resting-state EEG as Biomarker of Maladaptive Motor Function and Depressive Profile in Stroke Patients
- Author
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Marques, Lucas M., primary, Barbosa, Sara Pinto, additional, Gianlorenço, Anna Carolyna, additional, Pacheco-Barrios, K., additional, Souza, Daniel R., additional, Matheus, Denise, additional, Battistella, Linamara, additional, Simis, Marcel, additional, and Fregni, Felipe, additional
- Published
- 2024
- Full Text
- View/download PDF
4. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
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Brauer, M, Roth, G, Aravkin, A, Zheng, P, Abate, K, Abate, Y, Abbafati, C, Abbasgholizadeh, R, Abbasi, M, Abbasian, M, Abbasifard, M, Abbasi-Kangevari, M, Abd ElHafeez, S, Abd-Elsalam, S, Abdi, P, Abdollahi, M, Abdoun, M, Abdulah, D, Abdullahi, A, Abebe, M, Abedi, A, Abegaz, T, Abeldaño Zuñiga, R, Abiodun, O, Abiso, T, Aboagye, R, Abolhassani, H, Abouzid, M, Aboye, G, Abreu, L, Abualruz, H, Abubakar, B, Abu-Gharbieh, E, Abukhadijah, H, Aburuz, S, Abu-Zaid, A, Adane, M, Addo, I, Addolorato, G, Adedoyin, R, Adekanmbi, V, Aden, B, Adetunji, J, Adeyeoluwa, T, Adha, R, Adibi, A, Adnani, Q, Adzigbli, L, Afolabi, A, Afolabi, R, Afshin, A, Afyouni, S, Afzal, M, Afzal, S, Agampodi, S, Agbozo, F, Aghamiri, S, Agodi, A, Agrawal, A, Agyemang-Duah, W, Ahinkorah, B, Ahmad, A, Ahmad, D, Ahmad, F, Ahmad, N, Ahmad, S, Ahmad, T, Ahmed, A, Ahmed, L, Ahmed, M, Ahmed, S, Ajami, M, Akalu, G, Akara, E, Akbarialiabad, H, Akhlaghi, S, Akinosoglou, K, Akinyemiju, T, Akkaif, M, Akkala, S, Akombi-Inyang, B, Al Awaidy, S, Al Hasan, S, Alahdab, F, AL-Ahdal, T, Alalalmeh, S, Alalwan, T, Al-Aly, Z, Alam, K, Alam, N, Alanezi, F, Alanzi, T, Albakri, A, Albataineh, M, Aldhaleei, W, Aldridge, R, Alemayohu, M, Alemu, Y, Al-Fatly, B, Al-Gheethi, A, Al-Habbal, K, Alhabib, K, Alhassan, R, Ali, A, Ali, B, Ali, I, Ali, L, Ali, M, Ali, R, Ali, S, Ali, W, Alicandro, G, Alif, S, Aljunid, S, Alla, F, Al-Marwani, S, Al-Mekhlafi, H, Almustanyir, S, Alomari, M, Alonso, J, Alqahtani, J, Alqutaibi, A, Al-Raddadi, R, Alrawashdeh, A, Al-Rifai, R, Alrousan, S, Al-Sabah, S, Alshahrani, N, Altaany, Z, Altaf, A, Al-Tawfiq, J, Altirkawi, K, Aluh, D, Alvis-Guzman, N, Alvis-Zakzuk, N, Alwafi, H, Al-Wardat, M, Al-Worafi, Y, Aly, H, Aly, S, Alzoubi, K, Al-Zyoud, W, Amaechi, U, Aman Mohammadi, M, Amani, R, Amiri, S, Amirzade-Iranaq, M, Ammirati, E, Amu, H, Amugsi, D, Amusa, G, Ancuceanu, R, Anderlini, D, Anderson, J, Andrade, P, Andrei, C, Andrei, T, Anenberg, S, Angappan, D, Angus, C, Anil, A, Anil, S, Anjum, A, Anoushiravani, A, Antonazzo, I, Antony, C, Antriyandarti, E, Anuoluwa, B, Anvari, D, Anvari, S, Anwar, S, Anwer, R, Anyabolo, E, Anyasodor, A, Apostol, G, Arabloo, J, Arabzadeh Bahri, R, Arafat, M, Areda, D, Aregawi, B, Aremu, A, Armocida, B, Arndt, M, Ärnlöv, J, Arooj, M, Artamonov, A, Artanti, K, Aruleba, I, Arumugam, A, Asbeutah, A, Asgary, S, Asgedom, A, Ashbaugh, C, Ashemo, M, Ashraf, T, Askarinejad, A, Assmus, M, Astell-Burt, T, Athar, M, Athari, S, Atorkey, P, Atreya, A, Aujayeb, A, Ausloos, M, Avila-Burgos, L, Awoke, A, Ayala Quintanilla, B, Ayatollahi, H, Ayestas Portugal, C, Ayuso-Mateos, J, Azadnajafabad, S, Azevedo, R, Azhar, G, Azizi, H, Azzam, A, Backhaus, I, Badar, M, Badiye, A, Bagga, A, Baghdadi, S, Bagheri, N, Bagherieh, S, Bahrami Taghanaki, P, Bai, R, Baig, A, Baker, J, Bakkannavar, S, Balasubramanian, M, Baltatu, O, Bam, K, Bandyopadhyay, S, Banik, B, Banik, P, Banke-Thomas, A, Bansal, H, Barchitta, M, Bardhan, M, Bardideh, E, Barker-Collo, S, Bärnighausen, T, Barone-Adesi, F, Barqawi, H, Barrero, L, Barrow, A, Barteit, S, Basharat, Z, Basiru, A, Basso, J, Bastan, M, Basu, S, Batchu, S, Batra, K, Batra, R, Baune, B, Bayati, M, Bayileyegn, N, Beaney, T, Behnoush, A, Beiranvand, M, Béjot, Y, Bekele, A, Belgaumi, U, Bell, A, Bell, M, Bello, M, Bello, O, Belo, L, Beloukas, A, Bendak, S, Bennett, D, Bennitt, F, Bensenor, I, Benzian, H, Beran, A, Berezvai, Z, Bernabe, E, Bernstein, R, Bettencourt, P, Bhagavathula, A, Bhala, N, Bhandari, D, Bhardwaj, N, Bhardwaj, P, Bhaskar, S, Bhat, A, Bhat, V, Bhatti, G, Bhatti, J, Bhatti, M, Bhatti, R, Bhuiyan, M, Bhutta, Z, Bikbov, B, Bishai, J, Bisignano, C, Biswas, A, Biswas, B, Biswas, R, Bjørge, T, Boachie, M, Boakye, H, Bockarie, M, Bodolica, V, Bodunrin, A, Bogale, E, Bolla, S, Boloor, A, Bonakdar Hashemi, M, Boppana, S, Bora Basara, B, Borhany, H, Botero Carvajal, A, Bouaoud, S, Boufous, S, Bourne, R, Boxe, C, Braithwaite, D, Brant, L, Brar, A, Breitborde, N, Breitner, S, Brenner, H, Briko, A, Britton, G, Brown, C, Browne, A, Brunoni, A, Bryazka, D, Bulamu, N, Bulto, L, Buonsenso, D, Burkart, K, Burns, R, Busse, R, Bustanji, Y, Butt, N, Butt, Z, Caetano dos Santos, F, Cagney, J, Cahuana-Hurtado, L, Calina, D, Cámera, L, Campos, L, Campos-Nonato, I, Cao, C, Cao, F, Cao, Y, Capodici, A, Cárdenas, R, Carr, S, Carreras, G, Carrero, J, Carugno, A, Carvalho, F, Carvalho, M, Castaldelli-Maia, J, Castañeda-Orjuela, C, Castelpietra, G, Catalá-López, F, Catapano, A, Cattaruzza, M, Caye, A, Cederroth, C, Cegolon, L, Cenderadewi, M, Cercy, K, Cerin, E, Chadwick, J, Chakraborty, C, Chakraborty, P, Chakraborty, S, Chan, J, Chan, R, Chandan, J, Chandika, R, Chaturvedi, P, Chen, A, Chen, C, Chen, H, Chen, M, Chen, S, Cheng, C, Cheng, E, Cherbuin, N, Chi, G, Chichagi, F, Chimed-Ochir, O, Chimoriya, R, Ching, P, Chirinos-Caceres, J, Chitheer, A, Cho, W, Chong, B, Chopra, H, Chowdhury, R, Christopher, D, Chu, D, Chukwu, I, Chung, E, Chung, S, Chutiyami, M, Cioffi, I, Cogen, R, Cohen, A, Columbus, A, Conde, J, Corlateanu, A, Cortese, S, Cortesi, P, Costa, V, Costanzo, S, Criqui, M, Cruz, J, Cruz-Martins, N, Culbreth, G, da Silva, A, Dadras, O, Dai, X, Dai, Z, Daikwo, P, Dalli, L, Damiani, G, D'Amico, E, D'Anna, L, Darwesh, A, Das, J, Das, S, Dash, N, Dashti, M, Dávila-Cervantes, C, Davis Weaver, N, Davitoiu, D, De la Hoz, F, de la Torre-Luque, A, De Leo, D, Debopadhaya, S, Degenhardt, L, Del Bo', C, Delgado-Enciso, I, Delgado-Saborit, J, Demoze, C, Denova-Gutiérrez, E, Dervenis, N, Dervišević, E, Desai, H, Desai, R, Devanbu, V, Dewan, S, Dhali, A, Dhama, K, Dhane, A, Dhimal, M, Dhingra, S, Dhulipala, V, Dhungana, R, Dias da Silva, D, Diaz, D, Diaz, L, Diaz, M, Dima, A, Ding, D, Dinu, M, Djalalinia, S, Do, T, do Prado, C, Dodangeh, M, Dohare, S, Dokova, K, Dong, W, Dongarwar, D, D'Oria, M, Dorostkar, F, Dorsey, E, Doshi, R, Doshmangir, L, Dowou, R, Driscoll, T, Dsouza, A, Dsouza, H, Dumith, S, Duncan, B, Duraes, A, Duraisamy, S, Dushpanova, A, Dzianach, P, Dziedzic, A, Ebrahimi, A, Echieh, C, Ed-Dra, A, Edinur, H, Edvardsson, D, Edvardsson, K, Efendi, F, Eftekharimehrabad, A, Eini, E, Ekholuenetale, M, Ekundayo, T, El Arab, R, El Sayed Zaki, M, El-Dahiyat, F, Elemam, N, Elgar, F, Elgohary, G, Elhabashy, H, Elhadi, M, Elmehrath, A, Elmeligy, O, Elshaer, M, Elsohaby, I, Emeto, T, Esfandiari, N, Eshrati, B, Eslami, M, Esmaeili, S, Estep, K, Etaee, F, Fabin, N, Fagbamigbe, A, Fagbule, O, Fahimi, S, Falzone, L, Fareed, M, Farinha, C, Faris, M, Faris, P, Faro, A, Fasina, F, Fatehizadeh, A, Fauk, N, Fazylov, T, Feigin, V, Feng, X, Fereshtehnejad, S, Feroze, A, Ferrara, P, Ferrari, A, Ferreira, N, Fetensa, G, Feyisa, B, Filip, I, Fischer, F, Fitriana, I, Flavel, J, Flohr, C, Flood, D, Flor, L, Foigt, N, Folayan, M, Force, L, Fortuna, D, Foschi, M, Franklin, R, Freitas, A, Friedman, S, Fux, B, G, S, Gaal, P, Gaihre, S, Gajdács, M, Galali, Y, Gallus, S, Gandhi, A, Ganesan, B, Ganiyani, M, Garcia, V, Gardner, W, Garg, R, Gautam, R, Gebi, T, Gebregergis, M, Gebrehiwot, M, Gebremariam, T, Gebremeskel, T, Gerema, U, Getacher, L, Getahun, G, Getie, M, Ghadirian, F, Ghafarian, S, Ghaffari Jolfayi, A, Ghailan, K, Ghajar, A, Ghasemi, M, Ghasempour Dabaghi, G, Ghasemzadeh, A, Ghassemi, F, Ghazy, R, Gholami, A, Gholamrezanezhad, A, Gholizadeh, N, Ghorbani, M, Gil, A, Gil, G, Gilbertson, N, Gill, P, Gill, T, Gindaba, E, Girmay, A, Glasbey, J, Gnedovskaya, E, Göbölös, L, Godinho, M, Goel, A, Golechha, M, Goleij, P, Golinelli, D, Gomes, N, Gopalani, S, Gorini, G, Goudarzi, H, Goulart, A, Gouravani, M, Goyal, A, Graham, S, Grivna, M, Grosso, G, Guan, S, Guarducci, G, Gubari, M, Guha, A, Guicciardi, S, Gulati, S, Gulisashvili, D, Gunawardane, D, Guo, C, Gupta, A, Gupta, B, Gupta, M, Gupta, R, Gupta, S, Gupta, V, Habibzadeh, F, Habibzadeh, P, Hadaro, T, Hadian, Z, Haep, N, Haghi-Aminjan, H, Haghmorad, D, Hagins, H, Haile, D, Hailu, A, Hajj Ali, A, Halboub, E, Halimi, A, Hall, B, Haller, S, Halwani, R, Hamadeh, R, Hamdy, N, Hameed, S, Hamidi, S, Hammoud, A, Hanif, A, Hanifi, N, Haq, Z, Haque, M, Harapan, H, Hargono, A, Haro, J, Hasaballah, A, Hasan, I, Hasan, M, Hasan, S, Hasani, H, Hasanian, M, Hashmeh, N, Hasnain, M, Hassan, A, Hassan, I, Hassan Zadeh Tabatabaei, M, Hassani, S, Hassanipour, S, Hassankhani, H, Haubold, J, Havmoeller, R, Hay, S, Hebert, J, Hegazi, O, Hegena, T, Heidari, G, Heidari, M, Helfer, B, Hemmati, M, Henson, C, Herbert, M, Herteliu, C, Heuer, A, Hezam, K, Hinneh, T, Hiraike, Y, Hoan, N, Holla, R, Hon, J, Hoque, M, Horita, N, Hossain, S, Hosseini, S, Hosseinzadeh, H, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Hoven, H, Hsairi, M, Hsu, J, Hu, C, Huang, J, Huda, M, Hulland, E, Hultström, M, Hushmandi, K, Hussain, J, Hussein, N, Huynh, C, Huynh, H, Ibitoye, S, Idowu, O, Ihler, A, Ikeda, N, Ikuta, K, Ilesanmi, O, Ilic, I, Ilic, M, Imam, M, Immurana, M, Inbaraj, L, Irham, L, Isa, M, Islam, M, Ismail, F, Ismail, N, Iso, H, Isola, G, Iwagami, M, Iwu, C, Iwu-Jaja, C, J, V, Jaafari, J, Jacob, L, Jacobsen, K, Jadidi-Niaragh, F, Jahankhani, K, Jahanmehr, N, Jahrami, H, Jain, A, Jain, N, Jairoun, A, Jaiswal, A, Jakovljevic, M, Jalilzadeh Yengejeh, R, Jamora, R, Jatau, A, Javadov, S, Javaheri, T, Jayaram, S, Jeganathan, J, Jeswani, B, Jiang, H, Johnson, C, Jokar, M, Jomehzadeh, N, Jonas, J, Joo, T, Joseph, A, Joseph, N, Joshi, V, Joshua, C, Jozwiak, J, Jürisson, M, Kaambwa, B, Kabir, A, Kabir, Z, Kadashetti, V, Kahn, E, Kalani, R, Kaliyadan, F, Kalra, S, Kamath, R, Kanagasabai, T, Kanchan, T, Kandel, H, Kanmiki, E, Kanmodi, K, Kansal, S, Kapner, D, Kapoor, N, Karagiannidis, E, Karajizadeh, M, Karakasis, P, Karanth, S, Karaye, I, Karch, A, Karim, A, Karimi, H, Karmakar, S, Kashoo, F, Kasraei, H, Kassahun, W, Kassebaum, N, Kassel, M, Katikireddi, S, Kauppila, J, Kawakami, N, Kaydi, N, Kayode, G, Kazemi, F, Keiyoro, P, Kemmer, L, Kempen, J, Kerr, J, Kesse-Guyot, E, Khader, Y, Khafaie, M, Khajuria, H, Khalaji, A, Khalil, M, Khalilian, A, Khamesipour, F, Khan, A, Khan, M, Khanmohammadi, S, Khatab, K, Khatatbeh, H, Khatatbeh, M, Khatib, M, Khavandegar, A, Khayat Kashani, H, Khidri, F, Khodadoust, E, Khormali, M, Khorrami, Z, Khosla, A, Khosrowjerdi, M, Khreis, H, Khusun, H, Kifle, Z, Kim, K, Kim, M, Kim, Y, Kimokoti, R, Kisa, A, Kisa, S, Knibbs, L, Knudsen, A, Koh, D, Kolahi, A, Kompani, F, Kong, J, Koren, G, Korja, M, Korshunov, V, Korzh, O, Kosen, S, Kothari, N, Koul, P, Koulmane Laxminarayana, S, Krishan, K, Krishnamoorthy, V, Krishnamoorthy, Y, Krishnan, B, Krohn, K, Kuate Defo, B, Kucuk Bicer, B, Kuddus, M, Kugbey, N, Kuitunen, I, Kulimbet, M, Kulkarni, V, Kumar, A, Kumar, N, Kumar, V, Kundu, S, Kurmi, O, Kusnali, A, Kusuma, D, Kutluk, T, La Vecchia, C, Ladan, M, Laflamme, L, Lahariya, C, Lai, D, Lal, D, Lallukka, T, Lám, J, Lan, Q, Lan, T, Landires, I, Lanfranchi, F, Langguth, B, Lansingh, V, Laplante-Lévesque, A, Larijani, B, Larsson, A, Lasrado, S, Lauriola, P, Le, H, Le, L, Le, N, Le, T, Leasher, J, Ledda, C, Lee, M, Lee, P, Lee, S, Lee, Y, Legrand, K, Leigh, J, Leong, E, Lerango, T, Lescinsky, H, Leung, J, Li, M, Li, W, Li, Y, Li, Z, Ligade, V, Lim, L, Lim, S, Lin, R, Lin, S, Liu, C, Liu, G, Liu, J, Liu, R, Liu, S, Liu, W, Liu, X, Livingstone, K, Llanaj, E, Lohiya, A, López-Bueno, R, Lopukhov, P, Lorkowski, S, Lotufo, P, Lozano, R, Lubinda, J, Lucchetti, G, Luo, L, Lv, H, M Amin, H, Ma, Z, Maass, K, Mabrok, M, Machairas, N, Machoy, M, Mafhoumi, A, Magdy Abd El Razek, M, Maghazachi, A, Mahadeshwara Prasad, D, Maharaj, S, Mahmoud, M, Mahmoudi, E, Majeed, A, Makram, O, Makris, K, Malasala, S, Maled, V, Malhotra, K, Malik, A, Malik, I, Malinga, L, Malta, D, Mamun, A, Manda, A, Manla, Y, Mansour, A, Mansouri, B, Mansouri, P, Mansourian, M, Mansournia, M, Mantovani, L, Manu, E, Marateb, H, Maravilla, J, Marsh, E, Martinez, G, Martinez-Piedra, R, Martini, S, Martins-Melo, F, Martorell, M, Marx, W, Maryam, S, Mathangasinghe, Y, Mathioudakis, A, Matozinhos, F, Mattumpuram, J, Maugeri, A, Maulik, P, Mayeli, M, Mazidi, M, Mazzotti, A, Mcgrath, J, Mckee, M, Mckowen, A, Mclaughlin, S, Mcphail, M, Mcphail, S, Mechili, E, Mehmood, A, Mehmood, K, Mehrabani-Zeinabad, K, Mehrabi Nasab, E, Meier, T, Mejia-Rodriguez, F, Mekene Meto, T, Mekonnen, B, Menezes, R, Mengist, B, Mensah, G, Mensah, L, Mentis, A, Meo, S, Meretoja, A, Meretoja, T, Mersha, A, Mesfin, B, Mestrovic, T, Mettananda, K, Mettananda, S, Miazgowski, T, Micha, G, Michalek, I, Micheletti Gomide Nogueira de Sá, A, Miller, T, Mirarefin, M, Mirghafourvand, M, Mirica, A, Mirijello, A, Mirrakhimov, E, Mirshahi, A, Mirzaei, M, Mishra, A, Mishra, V, Mitchell, P, Mithra, P, Mittal, C, Moazen, B, Moberg, M, Mocciaro, G, Mohamadkhani, A, Mohamed, A, Mohamed, J, Mohamed, M, Mohamed, N, Mohammadi, E, Mohammadi, S, Mohammadian-Hafshejani, A, Mohammadifard, N, Mohammed, H, Mohammed, M, Mohammed, S, Mokdad, A, Monasta, L, Mondello, S, Moni, M, Moodi Ghalibaf, A, Moore, C, Moradi, M, Moradi, Y, Moraga, P, Morawska, L, Moreira, R, Morovatdar, N, Morrison, S, Morze, J, Mosaddeghi Heris, R, Mossialos, E, Motappa, R, Mougin, V, Mousavi, P, Msherghi, A, Mubarik, S, Muccioli, L, Mueller, U, Mulita, F, Mullany, E, Munjal, K, Murillo-Zamora, E, Murlimanju, B, Musina, A, Mustafa, G, Muthu, S, Muthupandian, S, Muthusamy, R, Muzaffar, M, Myung, W, Nafei, A, Nagarajan, A, Nagaraju, S, Nagel, G, Naghavi, M, Naghavi, P, Naik, G, Nainu, F, Nair, T, Najdaghi, S, Nakhostin Ansari, N, Nanavaty, D, Nangia, V, Narasimha Swamy, S, Narimani Davani, D, Nascimento, B, Nascimento, G, Nashwan, A, Natto, Z, Nauman, J, Navaratna, S, Naveed, M, Nayak, B, Nayak, V, Ndejjo, R, Nduaguba, S, Negash, H, Negoi, I, Negoi, R, Nejadghaderi, S, Nejjari, C, Nematollahi, M, Nepal, S, Neupane, S, Ng, M, Nguefack-Tsague, G, Ngunjiri, J, Nguyen, D, Nguyen, N, Nguyen, P, Nguyen, V, Nguyen Tran Minh, D, Niazi, R, Nicholson, S, Nie, J, Nikoobar, A, Nikpoor, A, Ningrum, D, Nnaji, C, Noman, E, Nomura, S, Noroozi, N, Norrving, B, Noubiap, J, Nri-Ezedi, C, Ntaios, G, Ntsekhe, M, Nunemo, M, Nurrika, D, Nutor, J, Oancea, B, O'Connell, E, Odetokun, I, O'Donnell, M, Oduro, M, Ogunfowokan, A, Ogunkoya, A, Oh, I, Okati-Aliabad, H, Okeke, S, Okekunle, A, Okonji, O, Olagunju, A, Olasupo, O, Olatubi, M, Oliveira, A, Oliveira, G, Olorukooba, A, Olufadewa, I, Olusanya, B, Olusanya, J, Oluwafemi, Y, Omar, H, Omar Bali, A, Omer, G, Ong, K, Ong, S, Onwujekwe, O, Onyedibe, K, Oppong, A, Ordak, M, Orish, V, Ornello, R, Orpana, H, Ortiz, A, Ortiz-Prado, E, Osman, W, Ostroff, S, Osuagwu, U, Otoiu, A, Otstavnov, N, Otstavnov, S, Ouyahia, A, Owolabi, M, Oyeyemi, I, Oyeyemi, O, P A, M, Pacheco-Barrios, K, Padron-Monedero, A, Padubidri, J, Pal, P, Palicz, T, Pan, F, Pan, H, Pana, A, Panda, S, Panda-Jonas, S, Pandey, A, Pandi-Perumal, S, Pangaribuan, H, Pantazopoulos, I, Pantea Stoian, A, Papadopoulou, P, Parent, M, Parija, P, Parikh, R, Park, S, Parsons, N, Pashaei, A, Pasovic, M, Passera, R, Patil, S, Patoulias, D, Patthipati, V, Paudel, U, Pawar, S, Pazoki Toroudi, H, Peden, A, Pedersini, P, Peng, M, Pensato, U, Pepito, V, Peprah, E, Peprah, P, Peres, M, Perianayagam, A, Perico, N, Perna, S, Pesudovs, K, Petcu, I, Petermann-Rocha, F, Pham, H, Philip, A, Phillips, M, Pickering, B, Pierannunzio, D, Pigeolet, M, Pigott, D, Piracha, Z, Piradov, M, Pisoni, E, Piyasena, M, Plass, D, Plotnikov, E, Poddighe, D, Polkinghorne, K, Poluru, R, Pond, C, Popovic, D, Porru, F, Postma, M, Poudel, G, Pour-Rashidi, A, Pourshams, A, Pourtaheri, N, Prabhu, D, Prada, S, Pradhan, J, Pradhan, P, Prasad, M, Prates, E, Purnobasuki, H, Purohit, B, Puvvula, J, Qasim, N, Qattea, I, Qazi, A, Qian, G, Qiu, S, Rabiee Rad, M, Radfar, A, Radhakrishnan, R, Radhakrishnan, V, Raeisi Shahraki, H, Rafferty, Q, Rafiei, A, Raggi, A, Raghav, P, Raheem, N, Rahim, F, Rahim, M, Rahimifard, M, Rahimi-Movaghar, V, Rahman, M, Rahmani, A, Rahmani, B, Rahmanian, M, Rahmanian, N, Rahmanian, V, Rahmati, M, Rahmawaty, S, Raimondo, D, Rajaa, S, Rajendran, V, Rajput, P, Ramadan, M, Ramasamy, S, Ramasubramani, P, Ramazanu, S, Ramteke, P, Rana, J, Rana, K, Ranabhat, C, Rane, A, Rani, U, Ranta, A, Rao, C, Rao, M, Rao, P, Rao, S, Rasella, D, Rashedi, S, Rashedi, V, Rashidi, M, Rasouli-Saravani, A, Ratan, Z, Rathnaiah Babu, G, Rauniyar, S, Rautalin, I, Rawaf, D, Rawaf, S, Rawassizadeh, R, Razo, C, Reda, Z, Reddy, M, Redwan, E, Reifels, L, Reitsma, M, Remuzzi, G, Reshmi, B, Resnikoff, S, Restaino, S, Reyes, L, Rezaei, M, Rezaei, N, Rezaeian, M, Rhee, T, Riaz, M, Ribeiro, A, Rickard, J, Robinson-Oden, H, Rodrigues, C, Rodrigues, M, Rodriguez, J, Roever, L, Romadlon, D, Ronfani, L, Rosauer, J, Roshandel, G, Rostamian, M, Rotimi, K, Rout, H, Roy, B, Roy, N, Rubagotti, E, Ruela, G, Rumisha, S, Runghien, T, Russo, M, Ruzzante, S, S N, C, Saad, A, Saber, K, Saber-Ayad, M, Sabour, S, Sacco, S, Sachdev, P, Sachdeva, R, Saddik, B, Saddler, A, Sadee, B, Sadeghi, E, Sadeghi, M, Sadeghi Majd, E, Saeb, M, Saeed, U, Safari, M, Safi, S, Sagar, R, Sagoe, D, Saheb Sharif-Askari, F, Saheb Sharif-Askari, N, Sahebkar, A, Sahoo, S, Sahu, M, Saif, Z, Sajid, M, Sakshaug, J, Salam, N, Salamati, P, Salami, A, Salaroli, L, Salehi, L, Salehi, S, Salem, M, Salihu, D, Salimi, S, Salum, G, Samadi Kafil, H, Samadzadeh, S, Samodra, Y, Samuel, V, Samy, A, Sanabria, J, Sanjeev, R, Sanna, F, Santomauro, D, Santric-Milicevic, M, Sarasmita, M, Saraswathy, S, Saravanan, A, Saravi, B, Sarikhani, Y, Sarmiento-Suárez, R, Sarode, G, Sarode, S, Sartorius, B, Sarveazad, A, Sathian, B, Sattin, D, Sawhney, M, Saya, G, Sayeed, A, Sayeed, M, Sayyah, M, Schinckus, C, Schmidt, M, Schuermans, A, Schumacher, A, Schutte, A, Schwarzinger, M, Schwebel, D, Schwendicke, F, Selvaraj, S, Semreen, M, Senthilkumaran, S, Serban, D, Serre, M, Sethi, Y, Shafie, M, Shah, H, Shah, N, Shah, P, Shah, S, Shahbandi, A, Shaheen, A, Shahid, S, Shahid, W, Shahsavari, H, Shahwan, M, Shaikh, M, Shaikh, S, Shalash, A, Sham, S, Shamim, M, Shams-Beyranvand, M, Shamshirgaran, M, Shamsi, M, Shanawaz, M, Shankar, A, Sharfaei, S, Sharifan, A, Sharifi-Rad, J, Sharma, M, Sharma, U, Sharma, V, Shastry, R, Shavandi, A, Shehabeldine, A, Shehzadi, S, Sheikh, A, Shen, J, Shetty, A, Shetty, B, Shetty, P, Shiani, A, Shiferaw, D, Shigematsu, M, Shin, M, Shiri, R, Shittu, A, Shiue, I, Shivakumar, K, Shivarov, V, Shool, S, Shorofi, S, Shrestha, R, Shrestha, S, Shuja, K, Shuval, K, Si, Y, Siddig, E, Silva, D, Silva, L, Silva, S, Silva, T, Simpson, C, Singh, A, Singh, B, Singh, G, Singh, H, Singh, J, Singh, M, Singh, N, Singh, P, Singh, S, Sinto, R, Sivakumar, S, Siwal, S, Skhvitaridze, N, Skou, S, Sleet, D, Sobia, F, Soboka, M, Socea, B, Solaimanian, S, Solanki, R, Solanki, S, Soliman, S, Somayaji, R, Song, Y, Sorensen, R, Soriano, J, Soyiri, I, Spartalis, M, Spearman, S, Spencer, C, Sreeramareddy, C, Stachteas, P, Stafford, L, Stanaway, J, Stanikzai, M, Stein, C, Stein, D, Steinbeis, F, Steiner, C, Steinke, S, Steiropoulos, P, Stockfelt, L, Stokes, M, Straif, K, Stranges, S, Subedi, N, Subramaniyan, V, Suleman, M, Suliankatchi Abdulkader, R, Sundström, J, Sunkersing, D, Sunnerhagen, K, Suresh, V, Swain, C, Szarpak, L, Szeto, M, Tabaee Damavandi, P, Tabarés-Seisdedos, R, Tabatabaei, S, Tabatabaei Malazy, O, Tabatabaeizadeh, S, Tabatabai, S, Tabche, C, Tabish, M, Tadakamadla, S, Taheri Abkenar, Y, Taheri Soodejani, M, Taherkhani, A, Taiba, J, Takahashi, K, Talaat, I, Tamuzi, J, Tan, K, Tang, H, Tat, N, Taveira, N, Tefera, Y, Tehrani-Banihashemi, A, Temesgen, W, Temsah, M, Teramoto, M, Terefa, D, Teye-Kwadjo, E, Thakur, R, Thangaraju, P, Thankappan, K, Thapar, R, Thayakaran, R, Thirunavukkarasu, S, Thomas, N, Tian, J, Tichopad, A, Ticoalu, J, Tiruye, T, Tobe-Gai, R, Tolani, M, Tolossa, T, Tonelli, M, Topor-Madry, R, Topouzis, F, Touvier, M, Tovani-Palone, M, Trabelsi, K, Tran, J, Tran, M, Tran, N, Trico, D, Trihandini, I, Troeger, C, Tromans, S, Truyen, T, Tsatsakis, A, Tsermpini, E, Tumurkhuu, M, Udoakang, A, Udoh, A, Ullah, A, Ullah, S, Umair, M, Umakanthan, S, Unim, B, Unnikrishnan, B, Upadhyay, E, Urso, D, Usman, J, Vaithinathan, A, Vakili, O, Valenti, M, Valizadeh, R, Van den Eynde, J, van Donkelaar, A, Varga, O, Vart, P, Varthya, S, Vasankari, T, Vasic, M, Vaziri, S, Venketasubramanian, N, Verghese, N, Verma, M, Veroux, M, Verras, G, Vervoort, D, Villafañe, J, Villalobos-Daniel, V, Villani, L, Villanueva, G, Vinayak, M, Violante, F, Vlassov, V, Vo, B, Vollset, S, Volovat, S, Vos, T, Vujcic, I, Waheed, Y, Wang, C, Wang, F, Wang, S, Wang, Y, Wanjau, M, Waqas, M, Ward, P, Waris, A, Wassie, E, Weerakoon, K, Weintraub, R, Weiss, D, Weiss, E, Weldetinsaa, H, Wells, K, Wen, Y, Wiangkham, T, Wickramasinghe, N, Wilkerson, C, Willeit, P, Wilson, S, Wong, Y, Wongsin, U, Wozniak, S, Wu, C, Wu, D, Wu, F, Wu, Z, Xia, J, Xiao, H, Xu, S, Xu, X, Xu, Y, Yadav, M, Yaghoubi, S, Yamagishi, K, Yang, L, Yano, Y, Yaribeygi, H, Yasufuku, Y, Ye, P, Yesodharan, R, Yesuf, S, Yezli, S, Yi, S, Yiğit, A, Yigzaw, Z, Yin, D, Yip, P, Yismaw, M, Yon, D, Yonemoto, N, You, Y, Younis, M, Yousefi, Z, Yu, C, Yu, Y, Zadey, S, Zadnik, V, Zakham, F, Zaki, N, Zakzuk, J, Zamagni, G, Zaman, S, Zandieh, G, Zanghì, A, Zar, H, Zare, I, Zarimeidani, F, Zastrozhin, M, Zeng, Y, Zhai, C, Zhang, A, Zhang, H, Zhang, L, Zhang, M, Zhang, Y, Zhang, Z, Zhao, H, Zhao, J, Zhao, X, Zhao, Y, Zhong, C, Zhou, J, Zhou, S, Zhu, B, Zhu, L, Zhu, Z, Ziaeian, B, Ziafati, M, Zielińska, M, Zimsen, S, Zoghi, G, Zoller, T, Zumla, A, Zyoud, S, Murray, C, Gakidou, E, Brauer, Michael, Roth, Gregory A, Aravkin, Aleksandr Y, Zheng, Peng, Abate, Kalkidan Hassen, Abate, Yohannes Habtegiorgis, Abbafati, Cristiana, Abbasgholizadeh, Rouzbeh, Abbasi, Madineh Akram, Abbasian, Mohammadreza, Abbasifard, Mitra, Abbasi-Kangevari, Mohsen, Abd ElHafeez, Samar, Abd-Elsalam, Sherief, Abdi, Parsa, Abdollahi, Mohammad, Abdoun, Meriem, Abdulah, Deldar Morad, Abdullahi, Auwal, Abebe, Mesfin, Abedi, Aidin, Abedi, Armita, Abegaz, Tadesse M, Abeldaño Zuñiga, Roberto Ariel, Abiodun, Olumide, Abiso, Temesgen Lera, Aboagye, Richard Gyan, Abolhassani, Hassan, Abouzid, Mohamed, Aboye, Girma Beressa, Abreu, Lucas Guimarães, Abualruz, Hasan, Abubakar, Bilyaminu, Abu-Gharbieh, Eman, Abukhadijah, Hana Jihad Jihad, Aburuz, Salahdein, Abu-Zaid, Ahmed, Adane, Mesafint Molla, Addo, Isaac Yeboah, Addolorato, Giovanni, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Aden, Bashir, Adetunji, Juliana Bunmi, Adeyeoluwa, Temitayo Esther, Adha, Rishan, Adibi, Amin, Adnani, Qorinah Estiningtyas Sakilah, Adzigbli, Leticia Akua, Afolabi, Aanuoluwapo Adeyimika, Afolabi, Rotimi Felix, Afshin, Ashkan, Afyouni, Shadi, Afzal, Muhammad Sohail, Afzal, Saira, Agampodi, Suneth Buddhika, Agbozo, Faith, Aghamiri, Shahin, Agodi, Antonella, Agrawal, Anurag, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahmad, Aqeel, Ahmad, Danish, Ahmad, Firdos, Ahmad, Noah, Ahmad, Shahzaib, Ahmad, Tauseef, Ahmed, Ali, Ahmed, Anisuddin, Ahmed, Ayman, Ahmed, Luai A, Ahmed, Muktar Beshir, Ahmed, Safoora, Ahmed, Syed Anees, Ajami, Marjan, Akalu, Gizachew Taddesse, Akara, Essona Matatom, Akbarialiabad, Hossein, Akhlaghi, Shiva, Akinosoglou, Karolina, Akinyemiju, Tomi, Akkaif, Mohammed Ahmed, Akkala, Sreelatha, Akombi-Inyang, Blessing, Al Awaidy, Salah, Al Hasan, Syed Mahfuz, Alahdab, Fares, AL-Ahdal, Tareq Mohammed Ali, Alalalmeh, Samer O, Alalwan, Tariq A, Al-Aly, Ziyad, Alam, Khurshid, Alam, Nazmul, Alanezi, Fahad Mashhour, Alanzi, Turki M, Albakri, Almaza, AlBataineh, Mohammad T, Aldhaleei, Wafa A, Aldridge, Robert W, Alemayohu, Mulubirhan Assefa, Alemu, Yihun Mulugeta, Al-Fatly, Bassam, Al-Gheethi, Adel Ali Saeed, Al-Habbal, Khairat, Alhabib, Khalid F, Alhassan, Robert Kaba, Ali, Abid, Ali, Amjad, Ali, Beriwan Abdulqadir, Ali, Iman, Ali, Liaqat, Ali, Mohammed Usman, Ali, Rafat, Ali, Syed Shujait Shujait, Ali, Waad, Alicandro, Gianfranco, Alif, Sheikh Mohammad, Aljunid, Syed Mohamed, Alla, François, Al-Marwani, Sabah, Al-Mekhlafi, Hesham M, Almustanyir, Sami, Alomari, Mahmoud A, Alonso, Jordi, Alqahtani, Jaber S, Alqutaibi, Ahmed Yaseen, Al-Raddadi, Rajaa M, Alrawashdeh, Ahmad, Al-Rifai, Rami Hani, Alrousan, Sahel Majed, Al-Sabah, Salman Khalifah, Alshahrani, Najim Z, Altaany, Zaid, Altaf, Awais, Al-Tawfiq, Jaffar A, Altirkawi, Khalid A, Aluh, Deborah Oyine, Alvis-Guzman, Nelson, Alvis-Zakzuk, Nelson J, Alwafi, Hassan, Al-Wardat, Mohammad Sami, Al-Worafi, Yaser Mohammed, Aly, Hany, Aly, Safwat, Alzoubi, Karem H, Al-Zyoud, Walid, Amaechi, Uchenna Anderson, Aman Mohammadi, Masous, Amani, Reza, Amiri, Sohrab, Amirzade-Iranaq, Mohammad Hosein, Ammirati, Enrico, Amu, Hubert, Amugsi, Dickson A, Amusa, Ganiyu Adeniyi, Ancuceanu, Robert, Anderlini, Deanna, Anderson, Jason A, Andrade, Pedro Prata, Andrei, Catalina Liliana, Andrei, Tudorel, Anenberg, Susan C, Angappan, Dhanalakshmi, Angus, Colin, Anil, Abhishek, Anil, Sneha, Anjum, Afifa, Anoushiravani, Amir, Antonazzo, Ippazio Cosimo, Antony, Catherine M, Antriyandarti, Ernoiz, Anuoluwa, Boluwatife Stephen, Anvari, Davood, Anvari, Saeid, Anwar, Saleha, Anwar, Sumadi Lukman, Anwer, Razique, Anyabolo, Ekenedilichukwu Emmanuel, Anyasodor, Anayochukwu Edward, Apostol, Geminn Louis 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L, Bakkannavar, Shankar M, Balasubramanian, Madhan, Baltatu, Ovidiu Constantin, Bam, Kiran, Bandyopadhyay, Soham, Banik, Biswajit, Banik, Palash Chandra, Banke-Thomas, Aduragbemi, Bansal, Hansi, Barchitta, Martina, Bardhan, Mainak, Bardideh, Erfan, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barone-Adesi, Francesco, Barqawi, Hiba Jawdat, Barrero, Lope H, Barrow, Amadou, Barteit, Sandra, Basharat, Zarrin, Basiru, Afisu, Basso, João Diogo, Bastan, Mohammad-Mahdi, Basu, Sanjay, Batchu, Sai, Batra, Kavita, Batra, Ravi, Baune, Bernhard T, Bayati, Mohsen, Bayileyegn, Nebiyou Simegnew, Beaney, Thomas, Behnoush, Amir Hossein, Beiranvand, Maryam, Béjot, Yannick, Bekele, Alehegn, Belgaumi, Uzma Iqbal, Bell, Arielle Wilder, Bell, Michelle L, Bello, Muhammad Bashir, Bello, Olorunjuwon Omolaja, Belo, Luis, Beloukas, Apostolos, Bendak, Salaheddine, Bennett, Derrick A, Bennitt, Fiona B, Bensenor, Isabela M, Benzian, Habib, Beran, Azizullah, Berezvai, Zombor, Bernabe, Eduardo, Bernstein, Robert S, Bettencourt, Paulo J G, Bhagavathula, Akshaya Srikanth, Bhala, Neeraj, Bhandari, Dinesh, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhaskar, Sonu, Bhat, Ajay Nagesh, Bhat, Vivek, Bhatti, Gurjit Kaur, Bhatti, Jasvinder Singh, Bhatti, Manpreet S, Bhatti, Rajbir, Bhuiyan, Mohiuddin Ahmed, Bhutta, Zulfiqar A, Bikbov, Boris, Bishai, Jessica Devin, Bisignano, Catherine, Biswas, Atanu, Biswas, Bijit, Biswas, Raaj Kishore, Bjørge, Tone, Boachie, Micheal Kofi, Boakye, Hosea, Bockarie, Moses John, Bodolica, Virginia, Bodunrin, Aadam Olalekan, Bogale, Eyob Ketema, Bolla, Srinivasa Rao, Boloor, Archith, Bonakdar Hashemi, Milad, Boppana, Sri Harsha, Bora Basara, Berrak, Borhany, Hamed, Botero Carvajal, Alejandro, Bouaoud, Souad, Boufous, Soufiane, Bourne, Rupert, Boxe, Christopher, Braithwaite, Dejana, Brant, Luisa C, Brar, Amanpreet, Breitborde, Nicholas J K, Breitner, Susanne, Brenner, Hermann, Briko, Andrey Nikolaevich, Britton, Gabrielle, Brown, Colin Stewart, Browne, Annie J, Brunoni, Andre R, Bryazka, Dana, Bulamu, Norma B, Bulto, Lemma N, Buonsenso, Danilo, Burkart, Katrin, Burns, Richard A, Busse, Reinhard, Bustanji, Yasser, Butt, Nadeem Shafique, Butt, Zahid A, Caetano dos Santos, Florentino Luciano, Cagney, Jack, Cahuana-Hurtado, Lucero, Calina, Daniela, Cámera, Luis Alberto, Campos, Luciana Aparecida, Campos-Nonato, Ismael R, Cao, Chao, Cao, Fan, Cao, Yubin, Capodici, Angelo, Cárdenas, Rosario, Carr, Sinclair, Carreras, Giulia, Carrero, Juan J, Carugno, Andrea, Carvalho, Felix, Carvalho, Márcia, Castaldelli-Maia, Joao Mauricio, Castañeda-Orjuela, Carlos A, Castelpietra, Giulio, Catalá-López, Ferrán, Catapano, Alberico L, Cattaruzza, Maria Sofia, Caye, Arthur, Cederroth, Christopher R, Cegolon, Luca, Cenderadewi, Muthia, Cercy, Kelly M, Cerin, Ester, Chadwick, Joshua, Chakraborty, Chiranjib, Chakraborty, Promit Ananyo, Chakraborty, Sandip, Chan, Jeffrey Shi Kai, Chan, Raymond N C, Chandan, Joht Singh, Chandika, Rama Mohan, Chaturvedi, Pankaj, Chen, An-Tian, Chen, Catherine S, Chen, Haowei, Chen, Meng Xuan, Chen, Mingling, Chen, Simiao, Cheng, Ching-Yu, Cheng, Esther T W, Cherbuin, Nicolas, Chi, Gerald, Chichagi, Fatemeh, Chimed-Ochir, Odgerel, Chimoriya, Ritesh, Ching, Patrick R, Chirinos-Caceres, Jesus Lorenzo, Chitheer, Abdulaal, Cho, William C S, Chong, Bryan, Chopra, Hitesh, Chowdhury, Rajiv, Christopher, Devasahayam J, Chu, Dinh-Toi, Chukwu, Isaac Sunday, Chung, Eric, Chung, Sheng-Chia, Chutiyami, Muhammad, Cioffi, Iolanda, Cogen, Rebecca M, Cohen, Aaron J, Columbus, Alyssa, Conde, Joao, Corlateanu, Alexandru, Cortese, Samuele, Cortesi, Paolo Angelo, Costa, Vera Marisa, Costanzo, Simona, Criqui, Michael H, Cruz, Jessica A, Cruz-Martins, Natália, Culbreth, Garland T, da Silva, Alanna Gomes, Dadras, Omid, Dai, Xiaochen, Dai, Zhaoli, Daikwo, Patience Unekwuojo, Dalli, Lachlan L, Damiani, Giovanni, D'Amico, Emanuele, D'Anna, Lucio, Darwesh, Aso Mohammad, Das, Jai K, Das, Subasish, Dash, Nihar Ranjan, Dashti, Mohsen, Dávila-Cervantes, Claudio 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Robert, Dsouza, Ashel Chelsea, Dsouza, Haneil Larson, Dumith, Samuel C, Duncan, Bruce B, Duraes, Andre Rodrigues, Duraisamy, Senbagam, Dushpanova, Anar, Dzianach, Paulina Agnieszka, Dziedzic, Arkadiusz Marian, Ebrahimi, Alireza, Echieh, Chidiebere Peter, Ed-Dra, Abdelaziz, Edinur, Hisham Atan, Edvardsson, David, Edvardsson, Kristina, Efendi, Ferry, Eftekharimehrabad, Aziz, Eini, Ebrahim, Ekholuenetale, Michael, Ekundayo, Temitope Cyrus, El Arab, Rabie Adel, El Sayed Zaki, Maysaa, El-Dahiyat, Faris, Elemam, Noha Mousaad, Elgar, Frank J, ElGohary, Ghada Metwally Tawfik, Elhabashy, Hala Rashad, Elhadi, Muhammed, Elmehrath, Ahmed O, Elmeligy, Omar Abdelsadek Abdou, Elshaer, Mohammed, Elsohaby, Ibrahim, Emeto, Theophilus I, Esfandiari, Negin, Eshrati, Babak, Eslami, Majid, Esmaeili, Sayed Vahid, Estep, Kara, Etaee, Farshid, Fabin, Natalia, Fagbamigbe, Adeniyi Francis, Fagbule, Omotayo Francis, Fahimi, Saman, Falzone, Luca, Fareed, Mohammad, Farinha, Carla Sofia e Sá, Faris, MoezAlIslam 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Bhawna, Gupta, Mohak, Gupta, Rahul, Gupta, Rajat Das, Gupta, Rajeev, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vijai Kumar, Gupta, Vivek Kumar, Habibzadeh, Farrokh, Habibzadeh, Parham, Hadaro, Tesfahun Simon, Hadian, Zahra, Haep, Nils, Haghi-Aminjan, Hamed, Haghmorad, Dariush, Hagins, Hailey, Haile, Demewoz, Hailu, Alemayehu, Hajj Ali, Adel, Halboub, Esam S, Halimi, Aram, Hall, Brian J, Haller, Sebastian, Halwani, Rabih, Hamadeh, Randah R, Hamdy, Nadia M, Hameed, Sajid, Hamidi, Samer, Hammoud, Ahmad, Hanif, Asif, Hanifi, Nasrin, Haq, Zaim Anan, Haque, Md Rabiul, Harapan, Harapan, Hargono, Arief, Haro, Josep Maria, Hasaballah, Ahmed I, Hasan, Ikramul, Hasan, Mohammad Jahid, Hasan, S M Mahmudul, Hasani, Hamidreza, Hasanian, Mohammad, Hashmeh, Nadim, Hasnain, Md Saquib, Hassan, Amr, Hassan, Ikrama, Hassan Zadeh Tabatabaei, Mahgol Sadat, Hassani, Shokoufeh, Hassanipour, Soheil, Hassankhani, Hadi, Haubold, Johannes, Havmoeller, Rasmus J, Hay, Simon I, Hebert, Jeffrey J, Hegazi, Omar E, Hegena, Tadele Yohannes, Heidari, Golnaz, Heidari, Mohammad, Helfer, Bartosz, Hemmati, Mehdi, Henson, Claire A, Herbert, Molly E, Herteliu, Claudiu, Heuer, Austin, Hezam, Kamal, Hinneh, Thomas Kwadwo, Hiraike, Yuta, Hoan, Nguyen Quoc, Holla, Ramesh, Hon, Julia, Hoque, Mohammad Enamul, Horita, Nobuyuki, Hossain, Sahadat, Hosseini, Seyed Ehsan, Hosseinzadeh, Hassan, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Hoven, Hanno, Hsairi, Mohamed, Hsu, Johnathan M, Hu, Chengxi, Huang, Junjie, Huda, Md Nazmul, Hulland, Erin N, Hultström, Michael, Hushmandi, Kiavash, Hussain, Javid, Hussein, Nawfal R, Huynh, Chantal K, Huynh, Hong-Han, Ibitoye, Segun Emmanuel, Idowu, Oluwatope Olaniyi, Ihler, Audrey L, Ikeda, Nayu, Ikuta, Kevin S, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Imam, Mohammad Tarique, Immurana, Mustapha, Inbaraj, Leeberk Raja, Irham, Lalu Muhammad, Isa, Mustafa Alhaji, Islam, Md Rabiul, Ismail, Faisal, Ismail, Nahlah Elkudssiah, Iso, Hiroyasu, Isola, Gaetano, Iwagami, Masao, Iwu, Chidozie C D, Iwu-Jaja, Chinwe Juliana, J, Vinothini, Jaafari, Jalil, Jacob, Louis, Jacobsen, Kathryn H, Jadidi-Niaragh, Farhad, Jahankhani, Kasra, Jahanmehr, Nader, Jahrami, Haitham, Jain, Akhil, Jain, Nityanand, Jairoun, Ammar Abdulrahman, Jaiswal, Abhishek, Jakovljevic, Mihajlo, Jalilzadeh Yengejeh, Reza, Jamora, Roland Dominic G, Jatau, Abubakar Ibrahim, Javadov, Sabzali, Javaheri, Tahereh, Jayaram, Shubha, Jeganathan, Jayakumar, Jeswani, Bijay Mukesh, Jiang, Heng, Johnson, Catherine O, Jokar, Mohammad, Jomehzadeh, Nabi, Jonas, Jost B, Joo, Tamas, Joseph, Abel, Joseph, Nitin, Joshi, Vivek, Joshua, Charity Ehimwenma, Jozwiak, Jacek Jerzy, Jürisson, Mikk, Kaambwa, Billingsley, Kabir, Ali, Kabir, Zubair, Kadashetti, Vidya, Kahn, Ethan M, Kalani, Rizwan, Kaliyadan, Feroze, Kalra, Sanjay, Kamath, Rajesh, Kanagasabai, Thanigaivelan, Kanchan, Tanuj, Kandel, Himal, Kanmiki, Edmund Wedam, Kanmodi, Kehinde Kazeem, Kansal, Sushil Kumar, Kapner, Daniel John, Kapoor, Neeti, Karagiannidis, Efstratios, Karajizadeh, Mehrdad, Karakasis, Paschalis, Karanth, Shama D, Karaye, Ibraheem M, Karch, André, Karim, Asima, Karimi, Hanie, Karmakar, Shilpi, Kashoo, Faizan Zaffar, Kasraei, Hengameh, Kassahun, Woldeteklehaymanot Dagne, Kassebaum, Nicholas J, Kassel, Molly B, Katikireddi, Srinivasa Vittal, Kauppila, Joonas H, Kawakami, Norito, Kaydi, Neda, Kayode, Gbenga A, Kazemi, Foad, Keiyoro, Peter Njenga, Kemmer, Laura, Kempen, John H, Kerr, Jessica A, Kesse-Guyot, Emmanuelle, Khader, Yousef Saleh, Khafaie, Morteza Abdullatif, Khajuria, Himanshu, Khalaji, Amirmohammad, Khalil, Mariam, Khalilian, Alireza, Khamesipour, Faham, Khan, Asaduzzaman, Khan, M Nuruzzaman, Khan, Maseer, Khan, Mohammad Jobair, Khan, Moien AB, Khanmohammadi, Shaghayegh, Khatab, Khaled, Khatatbeh, Haitham, Khatatbeh, Moawiah Mohammad, Khatib, Mahalaqua Nazli, Khavandegar, Armin, Khayat Kashani, Hamid Reza, Khidri, Feriha Fatima, Khodadoust, Elaheh, Khormali, Moein, Khorrami, Zahra, Khosla, Atulya Aman, Khosrowjerdi, Mahmood, Khreis, Haneen, Khusun, Helda, Kifle, Zemene Demelash, Kim, Kwanghyun, Kim, Min Seo, Kim, Yun Jin, Kimokoti, Ruth W, Kisa, Adnan, Kisa, Sezer, Knibbs, Luke D, Knudsen, Ann Kristin Skrindo, Koh, David S Q, Kolahi, Ali-Asghar, Kompani, Farzad, Kong, Jianqiu, Koren, Gerbrand, Korja, Miikka, Korshunov, Vladimir Andreevich, Korzh, Oleksii, Kosen, Soewarta, Kothari, Nikhil, Koul, Parvaiz A, Koulmane Laxminarayana, Sindhura Lakshmi, Krishan, Kewal, Krishnamoorthy, Vijay, Krishnamoorthy, Yuvaraj, Krishnan, Bindu, Krohn, Kris J, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kuddus, Md Abdul, Kuddus, Mohammed, Kugbey, Nuworza, Kuitunen, Ilari, Kulimbet, Mukhtar, Kulkarni, Vishnutheertha, Kumar, Ashish, Kumar, Nithin, Kumar, Vijay, Kundu, Satyajit, Kurmi, Om P, Kusnali, Asep, Kusuma, Dian, Kutluk, Tezer, La Vecchia, Carlo, Ladan, Muhammad Awwal, Laflamme, Lucie, Lahariya, Chandrakant, Lai, Daphne Teck Ching, Lal, Dharmesh Kumar, Lallukka, Tea, Lám, Judit, Lan, Qing, Lan, Tuo, Landires, Iván, Lanfranchi, Francesco, Langguth, Berthold, Lansingh, Van Charles, Laplante-Lévesque, Ariane, Larijani, Bagher, Larsson, Anders O, Lasrado, Savita, Lauriola, Paolo, Le, Huu-Hoai, Le, Long Khanh Dao, Le, Nhi Huu Hanh, Le, Thao Thi Thu, Leasher, Janet L, Ledda, Caterina, Lee, Munjae, Lee, Paul H, Lee, Seung Won, Lee, Shaun Wen Huey, Lee, Yo Han, LeGrand, Kate E, Leigh, James, Leong, Elvynna, Lerango, Temesgen L, Lescinsky, Haley, Leung, Janni, Li, Ming-Chieh, Li, Wang-Zhong, Li, Wei, Li, Yichong, Li, Zhihui, Ligade, Virendra S, Lim, Lee-Ling, Lim, Stephen S, Lin, Ro-Ting, Lin, Shuzhi, Liu, Chaojie, Liu, Gang, Liu, Jinli, Liu, Jue, Liu, Richard T, Liu, Shiwei, Liu, Wei, Liu, Xiaofeng, Liu, Xuefeng, Livingstone, Katherine M, Llanaj, Erand, Lohiya, Ayush, López-Bueno, Rubén, Lopukhov, Platon D, Lorkowski, Stefan, Lotufo, Paulo A, Lozano, Rafael, Lubinda, Jailos, Lucchetti, Giancarlo, Luo, Lisha, lv, Hengliang, M Amin, Hawraz Ibrahim, Ma, Zheng Feei, Maass, Kelsey Lynn, Mabrok, Mahmoud, Machairas, Nikolaos, Machoy, Monika, Mafhoumi, Asma, Magdy Abd El Razek, Mohammed, Maghazachi, Azzam A, Mahadeshwara Prasad, D R, Maharaj, Sandeep B, Mahmoud, Mansour Adam, Mahmoudi, Elham, Majeed, Azeem, Makram, Omar Mohamed, Makris, Konstantinos Christos, Malasala, Satyaveni, Maled, Venkatesh, Malhotra, Kashish, Malik, Ahmad Azam, Malik, Iram, Malinga, Lesibana Anthony, Malta, Deborah Carvalho, Mamun, Abdullah A, Manda, Ana Laura, Manla, Yosef, Mansour, Ali, Mansouri, Borhan, Mansouri, Pejman, Mansourian, Marjan, Mansournia, Mohammad Ali, Mantovani, Lorenzo Giovanni, Manu, Emmanuel, Marateb, Hamid Reza, Maravilla, Joemer C, Marsh, Elizabeth, Martinez, Gabriel, Martinez-Piedra, Ramon, Martini, Santi, Martins-Melo, Francisco Rogerlândio, Martorell, Miquel, Marx, Wolfgang, Maryam, Sharmeen, Mathangasinghe, Yasith, Mathioudakis, Alexander G, Matozinhos, Fernanda Penido, Mattumpuram, Jishanth, Maugeri, Andrea, Maulik, Pallab K, Mayeli, Mahsa, Mazidi, Mohsen, Mazzotti, Antonio, McGrath, John J, McKee, Martin, McKowen, Anna Laura W, McLaughlin, Susan A, McPhail, Michael A, McPhail, Steven M, Mechili, Enkeleint A, Mehmood, Asim, Mehmood, Khalid, Mehrabani-Zeinabad, Kamran, Mehrabi Nasab, Entezar, Meier, Toni, Mejia-Rodriguez, Fabiola, Mekene Meto, Tesfahun, Mekonnen, Birye Dessalegn, Menezes, Ritesh G, Mengist, Belayneh, Mensah, George A, Mensah, Laverne G, Mentis, Alexios-Fotios A, Meo, Sultan Ayoub, Meretoja, Atte, Meretoja, Tuomo J, Mersha, Abera M, Mesfin, Bezawit Afework, Mestrovic, Tomislav, Mettananda, Kukulege Chamila Dinushi, Mettananda, Sachith, Miazgowski, Tomasz, Micha, Georgia, Michalek, Irmina Maria, Micheletti Gomide Nogueira de Sá, Ana Carolina, Miller, Ted R, Mirarefin, Mojde, Mirghafourvand, Mojgan, Mirica, Andreea, Mirijello, Antonio, Mirrakhimov, Erkin M, Mirshahi, Arvin, Mirzaei, Maryam, Mishra, Ajay Kumar, Mishra, Vinaytosh, Mitchell, Philip B, Mithra, Prasanna, Mittal, Chaitanya, Moazen, Babak, Moberg, Madeline E, Mocciaro, Gabriele, Mohamadkhani, Ashraf, Mohamed, Abdalla Z, Mohamed, Ahmed Ismail, Mohamed, Jama, Mohamed, Mouhand F H, Mohamed, Nouh Saad, Mohammadi, Esmaeil, Mohammadi, Saeed, Mohammadian-Hafshejani, Abdollah, Mohammadifard, Noushin, Mohammed, Hussen, Mohammed, Mustapha, Mohammed, Salahuddin, Mohammed, Shafiu, Mokdad, Ali H, Monasta, Lorenzo, Mondello, Stefania, Moni, Mohammad Ali, Moodi Ghalibaf, AmirAli, Moore, Catrin E, Moradi, Maryam, Moradi, Yousef, Moraga, Paula, Morawska, Lidia, Moreira, Rafael Silveira, Morovatdar, Negar, Morrison, Shane Douglas, Morze, Jakub, Mosaddeghi Heris, Reza, Mossialos, Elias, Motappa, Rohith, Mougin, Vincent, Mousavi, Parsa, Msherghi, Ahmed, Mubarik, Sumaira, Muccioli, Lorenzo, Mueller, Ulrich Otto, Mulita, Francesk, Mullany, Erin C, Munjal, Kavita, Murillo-Zamora, Efrén, Murlimanju, BV, Musina, Ana-Maria, Mustafa, Ghulam, Muthu, Sathish, Muthupandian, Saravanan, Muthusamy, Raman, Muzaffar, Muhammad, Myung, Woojae, Nafei, Ayoub, Nagarajan, Ahamarshan Jayaraman, Nagaraju, Shankar Prasad, Nagel, Gabriele, Naghavi, Mohsen, Naghavi, Pirouz, Naik, Ganesh R, Naik, Gurudatta, Nainu, Firzan, Nair, Tapas Sadasivan, Najdaghi, Soroush, Nakhostin Ansari, Noureddin, Nanavaty, Dhairya P, Nangia, Vinay, Narasimha Swamy, Sreenivas, Narimani Davani, Delaram, Nascimento, Bruno Ramos, Nascimento, Gustavo G, Nashwan, Abdulqadir J, Natto, Zuhair S, Nauman, Javaid, Navaratna, Samidi N K, Naveed, Muhammad, Nayak, Biswa Prakash, Nayak, Vinod C, Ndejjo, Rawlance, Nduaguba, Sabina Onyinye, Negash, Hadush, Negoi, Ionut, Negoi, Ruxandra Irina, Nejadghaderi, Seyed Aria, Nejjari, Chakib, Nematollahi, Mohammad Hadi, Nepal, Samata, Neupane, Subas, Ng, Marie, Nguefack-Tsague, Georges, Ngunjiri, Josephine W, Nguyen, Dang H, Nguyen, Nhien Ngoc Y, Nguyen, Phat Tuan, Nguyen, Phuong The, Nguyen, Van Thanh, Nguyen Tran Minh, Duc, Niazi, Robina Khan, Nicholson, Sneha Ingle, Nie, Jing, Nikoobar, Ali, Nikpoor, Amin Reza, Ningrum, Dina Nur Anggraini, Nnaji, Chukwudi A, Noman, Efaq Ali, Nomura, Shuhei, Noroozi, Nafise, Norrving, Bo, Noubiap, Jean Jacques, Nri-Ezedi, Chisom Adaobi, Ntaios, George, Ntsekhe, Mpiko, Nunemo, Mengistu H, Nurrika, Dieta, Nutor, Jerry John, Oancea, Bogdan, O'Connell, Erin M, Odetokun, Ismail A, O'Donnell, Martin James, Oduro, Michael Safo, Ogunfowokan, Adesola Adenike, Ogunkoya, Abiola, Oh, In-Hwan, Okati-Aliabad, Hassan, Okeke, Sylvester Reuben, Okekunle, Akinkunmi Paul, Okonji, Osaretin Christabel, Olagunju, Andrew T, Olasupo, Omotola O, Olatubi, Matthew Idowu, Oliveira, Arão Belitardo, Oliveira, Gláucia Maria Moraes, Olorukooba, Abdulhakeem Abayomi, Olufadewa, Isaac Iyinoluwa, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Oluwafemi, Yinka Doris, Omar, Hany A, Omar Bali, Ahmed, Omer, Goran Latif, Ong, Kanyin Liane, Ong, Sokking, Onwujekwe, Obinna E, Onyedibe, Kenneth Ikenna, Oppong, Anita Frimpomaa, Ordak, Michal, Orish, Verner N, Ornello, Raffaele, Orpana, Heather M, Ortiz, Alberto, Ortiz-Prado, Esteban, Osman, Wael M S, Ostroff, Samuel M, Osuagwu, Uchechukwu Levi, Otoiu, Adrian, Otstavnov, Nikita, Otstavnov, Stanislav S, Ouyahia, Amel, Owolabi, Mayowa O, Oyeyemi, Ifeoluwa Temitayo, Oyeyemi, Oyetunde T, P A, Mahesh Padukudru, Pacheco-Barrios, Kevin, Padron-Monedero, Alicia, Padubidri, Jagadish Rao, Pal, Pramod Kumar, Palicz, Tamás, Pan, Feng, Pan, Hai-Feng, Pana, Adrian, Panda, Sujogya K, Panda-Jonas, Songhomitra, Pandey, Ashok, Pandi-Perumal, Seithikurippu R, Pangaribuan, Helena Ullyartha, Pantazopoulos, Ioannis, Pantea Stoian, Anca Mihaela, Papadopoulou, Paraskevi, Parent, Marie C, Parija, Pragyan Paramita, Parikh, Romil R, Park, Seoyeon, Park, Sungchul, Parsons, Nicholas, Pashaei, Ava, Pasovic, Maja, Passera, Roberto, Patil, Shankargouda, Patoulias, Dimitrios, Patthipati, Venkata Suresh, Paudel, Uttam, Pawar, Shrikant, Pazoki Toroudi, Hamidreza, Peden, Amy E, Pedersini, Paolo, Peng, Minjin, Pensato, Umberto, Pepito, Veincent Christian Filipino, Peprah, Emmanuel K, Peprah, Prince, Peres, Mario F P, Perianayagam, Arokiasamy, Perico, Norberto, Perna, Simone, Pesudovs, Konrad, Petcu, Ionela-Roxana, Petermann-Rocha, Fanny Emily, Pham, Hoang Tran, Philip, Anil K, Phillips, Michael R, Pickering, Brandon V, Pierannunzio, Daniela, Pigeolet, Manon, Pigott, David M, Piracha, Zahra Zahid, Piradov, Michael A, Pisoni, Enrico, Piyasena, Mapa Prabhath, Plass, Dietrich, Plotnikov, Evgenii, Poddighe, Dimitri, Polkinghorne, Kevan R, Poluru, Ramesh, Pond, Constance Dimity, Popovic, Djordje S, Porru, Fabio, Postma, Maarten J, Poudel, Govinda Raj, Pour-Rashidi, Ahmad, Pourshams, Akram, Pourtaheri, Naeimeh, Prabhu, Disha, Prada, Sergio I, Pradhan, Jalandhar, Pradhan, Pranil Man Singh, Prasad, Manya, Prates, Elton Junio Sady, Purnobasuki, Hery, Purohit, Bharathi M, Puvvula, Jagadeesh, Qasim, Nameer Hashim, Qattea, Ibrahim, Qazi, Asma Saleem, Qian, Gangzhen, Qiu, Suli, Rabiee Rad, Mehrdad, Radfar, Amir, Radhakrishnan, Raghu Anekal, Radhakrishnan, Venkatraman, Raeisi Shahraki, Hadi, Rafferty, Quinn, Rafiei, Alireza, Raggi, Alberto, Raghav, Pankaja Raghav, Raheem, Nasiru, Rahim, Fakher, Rahim, Md Jillur, Rahimifard, Mahban, Rahimi-Movaghar, Vafa, Rahman, Md Obaidur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rahmani, Bita, Rahmanian, Mohammad, Rahmanian, Nazanin, Rahmanian, Vahid, Rahmati, Masoud, Rahmawaty, Setyaningrum, Raimondo, Diego, Rajaa, Sathish, Rajendran, Vinoth, Rajput, Prashant, Ramadan, Mahmoud Mohammed, Ramasamy, Shakthi Kumaran, Ramasubramani, Premkumar, Ramazanu, Sheena, Ramteke, Pramod W, Rana, Juwel, Rana, Kritika, Ranabhat, Chhabi Lal, Rane, Amey, Rani, Usha, Ranta, Annemarei, Rao, Chythra R, Rao, Mithun, Rao, Puja C, Rao, Sowmya J, Rasella, Davide, Rashedi, Sina, Rashedi, Vahid, Rashidi, Mahsa, Rashidi, Mohammad-Mahdi, Rasouli-Saravani, Ashkan, Ratan, Zubair Ahmed, Rathnaiah Babu, Giridhara, Rauniyar, Santosh Kumar, Rautalin, Ilari, Rawaf, David Laith, Rawaf, Salman, Rawassizadeh, Reza, Razo, Christian, Reda, Zinabu Ferede Ferede, Reddy, Murali Mohan Rama Krishna, Redwan, Elrashdy Moustafa Mohamed, Reifels, Lennart, Reitsma, Marissa B, Remuzzi, Giuseppe, Reshmi, Bhageerathy, Resnikoff, Serge, Restaino, Stefano, Reyes, Luis Felipe, Rezaei, Maryam, Rezaei, Nazila, Rezaei, Negar, Rezaeian, Mohsen, Rhee, Taeho Gregory, Riaz, Mavra A, Ribeiro, Antonio Luiz P, Rickard, Jennifer, Robinson-Oden, Hannah Elizabeth, Rodrigues, Célia Fortuna, Rodrigues, Mónica, Rodriguez, Jefferson Antonio Buendia, Roever, Leonardo, Romadlon, Debby Syahru, Ronfani, Luca, Rosauer, Jennifer Jacqueline, Roshandel, Gholamreza, Rostamian, Morteza, Rotimi, Kunle, Rout, Himanshu Sekhar, Roy, Bedanta, Roy, Nitai, Rubagotti, Enrico, Ruela, Guilherme de Andrade, Rumisha, Susan Fred, Runghien, Tilleye, Russo, Michele, Ruzzante, Sacha Walde, S N, Chandan, Saad, Aly M A, Saber, Korosh, Saber-Ayad, Maha Mohamed, Sabour, Siamak, Sacco, Simona, Sachdev, Perminder S, Sachdeva, Rajesh, Saddik, Basema, Saddler, Adam, Sadee, Bashdar Abuzed, Sadeghi, Ehsan, Sadeghi, Masoumeh, Sadeghi Majd, Elham, Saeb, Mohammad Reza, Saeed, Umar, Safari, Mehdi, Safi, Sare, Safi, Sher Zaman, Sagar, Rajesh, Sagoe, Dominic, Saheb Sharif-Askari, Fatemeh, Saheb Sharif-Askari, Narjes, Sahebkar, Amirhossein, Sahoo, Soumya Swaroop, Sahu, Monalisha, Saif, Zahra, Sajid, Mirza Rizwan, Sakshaug, Joseph W, Salam, Nasir, Salamati, Payman, Salami, Afeez Abolarinwa, Salaroli, Luciane B, Salehi, Leili, Salehi, Sana, Salem, Marwa Rashad, Salem, Mohammed Z Y, Salihu, Dauda, Salimi, Sohrab, Salum, Giovanni A, Samadi Kafil, Hossein, Samadzadeh, Sara, Samodra, Yoseph Leonardo, Samuel, Vijaya Paul, Samy, Abdallah M, Sanabria, Juan, Sanjeev, Rama Krishna, Sanna, Francesca, Santomauro, Damian Francesco, Santric-Milicevic, Milena M, Sarasmita, Made Ary, Saraswathy, Sivan Yegnanarayana Iyer, Saravanan, Aswini, Saravi, Babak, Sarikhani, Yaser, Sarmiento-Suárez, Rodrigo, Sarode, Gargi Sachin, Sarode, Sachin C, Sartorius, Benn, Sarveazad, Arash, Sathian, Brijesh, Sattin, Davide, Sawhney, Monika, Saya, Ganesh Kumar, Sayeed, Abu, Sayeed, Md Abu, Sayyah, Mehdi, Schinckus, Christophe, Schmidt, Maria Inês, Schuermans, Art, Schumacher, Austin E, Schutte, Aletta Elisabeth, Schwarzinger, Michaël, Schwebel, David C, Schwendicke, Falk, Selvaraj, Siddharthan, Semreen, Mohammad H, Senthilkumaran, Subramanian, Serban, Dragos, Serre, Marc L, Sethi, Yashendra, Shafie, Mahan, Shah, Humaira, Shah, Nilay S, Shah, Pritik A, Shah, Syed Mahboob, Shahbandi, Ataollah, Shaheen, Amira A, Shahid, Samiah, Shahid, Wajeehah, Shahsavari, Hamid R, Shahwan, Moyad Jamal, Shaikh, Masood Ali, Shaikh, Summaiya Zareen, Shalash, Ali S, Sham, Sunder, Shamim, Muhammad Aaqib, Shams-Beyranvand, Mehran, Shamshirgaran, Mohammad Ali, Shamsi, Mohammad Anas, Shanawaz, Mohd, Shankar, Abhishek, Sharfaei, Sadaf, Sharifan, Amin, Sharifi-Rad, Javad, Sharma, Manoj, Sharma, Ujjawal, Sharma, Vishal, Shastry, Rajesh P, Shavandi, Amin, Shehabeldine, Amr Mohamed Elsayed, Shehzadi, Somia, Sheikh, Aziz, Shen, Jiabin, Shetty, Adithi, Shetty, B Suresh Kumar, Shetty, Pavanchand H, Shiani, Amir, Shiferaw, Desalegn, Shigematsu, Mika, Shin, Min-Jeong, Shiri, Rahman, Shittu, Aminu, Shiue, Ivy, Shivakumar, K M, Shivarov, Velizar, Shool, Sina, Shorofi, Seyed Afshin, Shrestha, Rajan, Shrestha, Sunil, Shuja, Kanwar Hamza, Shuval, Kerem, Si, Yafei, Siddig, Emmanuel Edwar, Silva, Diego Augusto Santos, Silva, Luís Manuel Lopes Rodrigues, Silva, Soraia, Silva, Thales Philipe R, Simpson, Colin R, Singh, Abhinav, Singh, Balbir Bagicha, Singh, Baljinder, Singh, Garima, Singh, Harmanjit, Singh, Jasvinder A, Singh, Mahendra, Singh, Narinder Pal, Singh, Paramdeep, Singh, Surjit, Sinto, Robert, Sivakumar, Shravan, Siwal, Samarjeet Singh, Skhvitaridze, Natia, Skou, Søren T, Sleet, David A, Sobia, Farrukh, Soboka, Matiwos, Socea, Bogdan, Solaimanian, Shahabaddin, Solanki, Ranjan, Solanki, Shipra, Soliman, Sameh S M, Somayaji, Ranjani, Song, Yi, Sorensen, Reed J D, Soriano, Joan B, Soyiri, Ireneous N, Spartalis, Michael, Spearman, Sandra, Spencer, Cory N, Sreeramareddy, Chandrashekhar T, Stachteas, Panagiotis, Stafford, Lauryn K, Stanaway, Jeffrey D, Stanikzai, Muhammad Haroon, Stein, Caroline, Stein, Dan J, Steinbeis, Fridolin, Steiner, Caitlyn, Steinke, Sabine, Steiropoulos, Paschalis, Stockfelt, Leo, Stokes, Mark A, Straif, Kurt, Stranges, Saverio, Subedi, Narayan, Subramaniyan, Vetriselvan, Suleman, Muhammad, Suliankatchi Abdulkader, Rizwan, Sundström, Johan, Sunkersing, David, Sunnerhagen, Katharina S, Suresh, Vinay, Swain, Chandan Kumar, Szarpak, Lukasz, Szeto, Mindy D, Tabaee Damavandi, Payam, Tabarés-Seisdedos, Rafael, Tabatabaei, Seyyed Mohammad, Tabatabaei Malazy, Ozra, Tabatabaeizadeh, Seyed-Amir, Tabatabai, Shima, Tabche, Celine, Tabish, Mohammad, Tadakamadla, Santosh Kumar, Taheri Abkenar, Yasaman, Taheri Soodejani, Moslem, Taherkhani, Amir, Taiba, Jabeen, Takahashi, Ken, Talaat, Iman M, Tamuzi, Jacques Lukenze, Tan, Ker-Kan, Tang, Haosu, Tat, Nathan Y, Taveira, Nuno, Tefera, Yibekal Manaye, Tehrani-Banihashemi, Arash, Temesgen, Worku Animaw, Temsah, Mohamad-Hani, Teramoto, Masayuki, Terefa, Dufera Rikitu, Teye-Kwadjo, Enoch, Thakur, Ramna, Thangaraju, Pugazhenthan, Thankappan, Kavumpurathu Raman, Thapar, Rekha, Thayakaran, Rasiah, Thirunavukkarasu, Sathish, Thomas, Nihal, Thomas, Nikhil Kenny, Tian, Jing, Tichopad, Ales, Ticoalu, Jansje Henny Vera, Tiruye, Tenaw Yimer, Tobe-Gai, Ruoyan, Tolani, Musliu Adetola, Tolossa, Tadesse, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Fotis, Touvier, Mathilde, Tovani-Palone, Marcos Roberto, Trabelsi, Khaled, Tran, Jasmine T, Tran, Mai Thi Ngoc, Tran, Nghia Minh, Trico, Domenico, Trihandini, Indang, Troeger, Christopher E, Tromans, Samuel Joseph, Truyen, Thien Tan Tri Tai, Tsatsakis, Aristidis, Tsermpini, Evangelia Eirini, Tumurkhuu, Munkhtuya, Udoakang, Aniefiok John, Udoh, Arit, Ullah, Atta, Ullah, Saeed, Ullah, Sana, Umair, Muhammad, Umakanthan, Srikanth, Unim, Brigid, Unnikrishnan, Bhaskaran, Upadhyay, Era, Urso, Daniele, Usman, Jibrin Sammani, Vaithinathan, Asokan Govindaraj, Vakili, Omid, Valenti, Mario, Valizadeh, Rohollah, Van den Eynde, Jef, van Donkelaar, Aaron, Varga, Orsolya, Vart, Priya, Varthya, Shoban Babu, Vasankari, Tommi Juhani, Vasic, Milena, Vaziri, Siavash, Venketasubramanian, Narayanaswamy, Verghese, Nicholas Alexander, Verma, Madhur, Veroux, Massimiliano, Verras, Georgios-Ioannis, Vervoort, Dominique, Villafañe, Jorge Hugo, Villalobos-Daniel, Victor E, Villani, Leonardo, Villanueva, Gabriela Ines, Vinayak, Manish, Violante, Francesco S, Vlassov, Vasily, Vo, Bay, Vollset, Stein Emil, Volovat, Simona Ruxandra, Vos, Theo, Vujcic, Isidora S, Waheed, Yasir, Wang, Cong, Wang, Fang, Wang, Shu, Wang, Yanzhong, Wang, Yuan-Pang, Wanjau, Mary Njeri, Waqas, Muhammad, Ward, Paul, Waris, Abdul, Wassie, Emebet Gashaw, Weerakoon, Kosala Gayan, Weintraub, Robert G, Weiss, Daniel J, Weiss, Eli J, Weldetinsaa, Haftom Legese Legese, Wells, Katherine M, Wen, Yi Feng, Wiangkham, Taweewat, Wickramasinghe, Nuwan Darshana, Wilkerson, Caroline, Willeit, Peter, Wilson, Shadrach, Wong, Yen Jun, Wongsin, Utoomporn, Wozniak, Sarah, Wu, Chenkai, Wu, Dongze, Wu, Felicia, Wu, Zenghong, Xia, Juan, Xiao, Hong, Xu, Suowen, Xu, Xiaoyue, Xu, Yvonne Yiru, Yadav, Mukesh Kumar, Yaghoubi, Sajad, Yamagishi, Kazumasa, Yang, Lin, Yano, Yuichiro, Yaribeygi, Habib, Yasufuku, Yuichi, Ye, Pengpeng, Yesodharan, Renjulal, Yesuf, Subah Abderehim, Yezli, Saber, Yi, Siyan, Yiğit, Arzu, Yigzaw, Zeamanuel Anteneh, Yin, Dehui, Yip, Paul, Yismaw, Malede Berihun, Yon, Dong Keon, Yonemoto, Naohiro, You, Yuyi, Younis, Mustafa Z, Yousefi, Zabihollah, Yu, Chuanhua, Yu, Yong, Zadey, Siddhesh, Zadnik, Vesna, Zakham, Fathiah, Zaki, Nazar, Zakzuk, Josefina, Zamagni, Giulia, Zaman, Sojib Bin, Zandieh, Ghazal G Z, Zanghì, Aurora, Zar, Heather J, Zare, Iman, Zarimeidani, Fatemeh, Zastrozhin, Mikhail Sergeevich, Zeng, Youjie, Zhai, Chunxia, Zhang, Anthony Lin, Zhang, Haijun, Zhang, Liqun, Zhang, Meixin, Zhang, Yunquan, Zhang, Zhenyu, Zhang, Zhi-Jiang, Zhao, Hanqing, Zhao, Jeff T, Zhao, Xiu-Ju George, Zhao, Yang, Zhao, Yong, Zhong, Chenwen, Zhou, Jingjing, Zhou, Juexiao, Zhou, Shangcheng, Zhu, Bin, Zhu, Lei, Zhu, Zhaohua, Ziaeian, Boback, Ziafati, Makan, Zielińska, Magdalena, Zimsen, Stephanie R M, Zoghi, Ghazal, Zoller, Thomas, Zumla, Alimuddin, Zyoud, Sa'ed H, Zyoud, Samer H, Murray, Christopher J L, Gakidou, Emmanuela, Brauer, M, Roth, G, Aravkin, A, Zheng, P, Abate, K, Abate, Y, Abbafati, C, Abbasgholizadeh, R, Abbasi, M, Abbasian, M, Abbasifard, M, Abbasi-Kangevari, M, Abd ElHafeez, S, Abd-Elsalam, S, Abdi, P, Abdollahi, M, Abdoun, M, Abdulah, D, Abdullahi, A, Abebe, M, Abedi, A, Abegaz, T, Abeldaño Zuñiga, R, Abiodun, O, Abiso, T, Aboagye, R, Abolhassani, H, Abouzid, M, Aboye, G, Abreu, L, Abualruz, H, Abubakar, B, Abu-Gharbieh, E, Abukhadijah, H, Aburuz, S, Abu-Zaid, A, Adane, M, Addo, I, Addolorato, G, Adedoyin, R, Adekanmbi, V, Aden, B, Adetunji, J, Adeyeoluwa, T, Adha, R, Adibi, A, Adnani, Q, Adzigbli, L, Afolabi, A, Afolabi, R, Afshin, A, Afyouni, S, Afzal, M, Afzal, S, Agampodi, S, Agbozo, F, Aghamiri, S, Agodi, A, Agrawal, A, Agyemang-Duah, W, Ahinkorah, B, Ahmad, A, Ahmad, D, Ahmad, F, Ahmad, N, Ahmad, S, Ahmad, T, Ahmed, A, Ahmed, L, Ahmed, M, Ahmed, S, Ajami, M, Akalu, G, Akara, E, Akbarialiabad, H, Akhlaghi, S, Akinosoglou, K, Akinyemiju, T, Akkaif, M, Akkala, S, Akombi-Inyang, B, Al Awaidy, S, Al Hasan, S, Alahdab, F, AL-Ahdal, T, Alalalmeh, S, Alalwan, T, Al-Aly, Z, Alam, K, Alam, N, Alanezi, F, Alanzi, T, Albakri, A, Albataineh, M, Aldhaleei, W, Aldridge, R, Alemayohu, M, Alemu, Y, Al-Fatly, B, Al-Gheethi, A, Al-Habbal, K, Alhabib, K, Alhassan, R, Ali, A, Ali, B, Ali, I, Ali, L, Ali, M, Ali, R, Ali, S, Ali, W, Alicandro, G, Alif, S, Aljunid, S, Alla, F, Al-Marwani, S, Al-Mekhlafi, H, Almustanyir, S, Alomari, M, Alonso, J, Alqahtani, J, Alqutaibi, A, Al-Raddadi, R, Alrawashdeh, A, Al-Rifai, R, Alrousan, S, Al-Sabah, S, Alshahrani, N, Altaany, Z, Altaf, A, Al-Tawfiq, J, Altirkawi, K, Aluh, D, Alvis-Guzman, N, Alvis-Zakzuk, N, Alwafi, H, Al-Wardat, M, Al-Worafi, Y, Aly, H, Aly, S, Alzoubi, K, Al-Zyoud, W, Amaechi, U, Aman Mohammadi, M, Amani, R, Amiri, S, Amirzade-Iranaq, M, Ammirati, E, Amu, H, Amugsi, D, Amusa, G, Ancuceanu, R, Anderlini, D, Anderson, J, Andrade, P, Andrei, C, Andrei, T, Anenberg, S, Angappan, D, Angus, C, Anil, A, Anil, S, Anjum, A, Anoushiravani, A, Antonazzo, I, Antony, C, Antriyandarti, E, Anuoluwa, B, Anvari, D, Anvari, S, Anwar, S, Anwer, R, Anyabolo, E, Anyasodor, A, Apostol, G, Arabloo, J, Arabzadeh Bahri, R, Arafat, M, Areda, D, Aregawi, B, Aremu, A, Armocida, B, Arndt, M, Ärnlöv, J, Arooj, M, Artamonov, A, Artanti, K, Aruleba, I, Arumugam, A, Asbeutah, A, Asgary, S, Asgedom, A, Ashbaugh, C, Ashemo, M, Ashraf, T, Askarinejad, A, Assmus, M, Astell-Burt, T, Athar, M, Athari, S, Atorkey, P, Atreya, A, Aujayeb, A, Ausloos, M, Avila-Burgos, L, Awoke, A, Ayala Quintanilla, B, Ayatollahi, H, Ayestas Portugal, C, Ayuso-Mateos, J, Azadnajafabad, S, Azevedo, R, Azhar, G, Azizi, H, Azzam, A, Backhaus, I, Badar, M, Badiye, A, Bagga, A, Baghdadi, S, Bagheri, N, Bagherieh, S, Bahrami Taghanaki, P, Bai, R, Baig, A, Baker, J, Bakkannavar, S, Balasubramanian, M, Baltatu, O, Bam, K, Bandyopadhyay, S, Banik, B, Banik, P, Banke-Thomas, A, Bansal, H, Barchitta, M, Bardhan, M, Bardideh, E, Barker-Collo, S, Bärnighausen, T, Barone-Adesi, F, Barqawi, H, Barrero, L, Barrow, A, Barteit, S, Basharat, Z, Basiru, A, Basso, J, Bastan, M, Basu, S, Batchu, S, Batra, K, Batra, R, Baune, B, Bayati, M, Bayileyegn, N, Beaney, T, Behnoush, A, Beiranvand, M, Béjot, Y, Bekele, A, Belgaumi, U, Bell, A, Bell, M, Bello, M, Bello, O, Belo, L, Beloukas, A, Bendak, S, Bennett, D, Bennitt, F, Bensenor, I, Benzian, H, Beran, A, Berezvai, Z, Bernabe, E, Bernstein, R, Bettencourt, P, Bhagavathula, A, Bhala, N, Bhandari, D, Bhardwaj, N, Bhardwaj, P, Bhaskar, S, Bhat, A, Bhat, V, Bhatti, G, Bhatti, J, Bhatti, M, Bhatti, R, Bhuiyan, M, Bhutta, Z, Bikbov, B, Bishai, J, Bisignano, C, Biswas, A, Biswas, B, Biswas, R, Bjørge, T, Boachie, M, Boakye, H, Bockarie, M, Bodolica, V, Bodunrin, A, Bogale, E, Bolla, S, Boloor, A, Bonakdar Hashemi, M, Boppana, S, Bora Basara, B, Borhany, H, Botero Carvajal, A, Bouaoud, S, Boufous, S, Bourne, R, Boxe, C, Braithwaite, D, Brant, L, Brar, A, Breitborde, N, Breitner, S, Brenner, H, Briko, A, Britton, G, Brown, C, Browne, A, Brunoni, A, Bryazka, D, Bulamu, N, Bulto, L, Buonsenso, D, Burkart, K, Burns, R, Busse, R, Bustanji, Y, Butt, N, Butt, Z, Caetano dos Santos, F, Cagney, J, Cahuana-Hurtado, L, Calina, D, Cámera, L, Campos, L, Campos-Nonato, I, Cao, C, Cao, F, Cao, Y, Capodici, A, Cárdenas, R, Carr, S, Carreras, G, Carrero, J, Carugno, A, Carvalho, F, Carvalho, M, Castaldelli-Maia, J, Castañeda-Orjuela, C, Castelpietra, G, Catalá-López, F, Catapano, A, Cattaruzza, M, Caye, A, Cederroth, C, Cegolon, L, Cenderadewi, M, Cercy, K, Cerin, E, Chadwick, J, Chakraborty, C, Chakraborty, P, Chakraborty, S, Chan, J, Chan, R, Chandan, J, Chandika, R, Chaturvedi, P, Chen, A, Chen, C, Chen, H, Chen, M, Chen, S, Cheng, C, Cheng, E, Cherbuin, N, Chi, G, Chichagi, F, Chimed-Ochir, O, Chimoriya, R, Ching, P, Chirinos-Caceres, J, Chitheer, A, Cho, W, Chong, B, Chopra, H, Chowdhury, R, Christopher, D, Chu, D, Chukwu, I, Chung, E, Chung, S, Chutiyami, M, Cioffi, I, Cogen, R, Cohen, A, Columbus, A, Conde, J, Corlateanu, A, Cortese, S, Cortesi, P, Costa, V, Costanzo, S, Criqui, M, Cruz, J, Cruz-Martins, N, Culbreth, G, da Silva, A, Dadras, O, Dai, X, Dai, Z, Daikwo, P, Dalli, L, Damiani, G, D'Amico, E, D'Anna, L, Darwesh, A, Das, J, Das, S, Dash, N, Dashti, M, Dávila-Cervantes, C, Davis Weaver, N, Davitoiu, D, De la Hoz, F, de la Torre-Luque, A, De Leo, D, Debopadhaya, S, Degenhardt, L, Del Bo', C, Delgado-Enciso, I, Delgado-Saborit, J, Demoze, C, Denova-Gutiérrez, E, Dervenis, N, Dervišević, E, Desai, H, Desai, R, Devanbu, V, Dewan, S, Dhali, A, Dhama, K, Dhane, A, Dhimal, M, Dhingra, S, Dhulipala, V, Dhungana, R, Dias da Silva, D, Diaz, D, Diaz, L, Diaz, M, Dima, A, Ding, D, Dinu, M, Djalalinia, S, Do, T, do Prado, C, Dodangeh, M, Dohare, S, Dokova, K, Dong, W, Dongarwar, D, D'Oria, M, Dorostkar, F, Dorsey, E, Doshi, R, Doshmangir, L, Dowou, R, Driscoll, T, Dsouza, A, Dsouza, H, Dumith, S, Duncan, B, Duraes, A, Duraisamy, S, Dushpanova, A, Dzianach, P, Dziedzic, A, Ebrahimi, A, Echieh, C, Ed-Dra, A, Edinur, H, Edvardsson, D, Edvardsson, K, Efendi, F, Eftekharimehrabad, A, Eini, E, Ekholuenetale, M, Ekundayo, T, El Arab, R, El Sayed Zaki, M, El-Dahiyat, F, Elemam, N, Elgar, F, Elgohary, G, Elhabashy, H, Elhadi, M, Elmehrath, A, Elmeligy, O, Elshaer, M, Elsohaby, I, Emeto, T, Esfandiari, N, Eshrati, B, Eslami, M, Esmaeili, S, Estep, K, Etaee, F, Fabin, N, Fagbamigbe, A, Fagbule, O, Fahimi, S, Falzone, L, Fareed, M, Farinha, C, Faris, M, Faris, P, Faro, A, Fasina, F, Fatehizadeh, A, Fauk, N, Fazylov, T, Feigin, V, Feng, X, Fereshtehnejad, S, Feroze, A, Ferrara, P, Ferrari, A, Ferreira, N, Fetensa, G, Feyisa, B, Filip, I, Fischer, F, Fitriana, I, Flavel, J, Flohr, C, Flood, D, Flor, L, Foigt, N, Folayan, M, Force, L, Fortuna, D, Foschi, M, Franklin, R, Freitas, A, Friedman, S, Fux, B, G, S, Gaal, P, Gaihre, S, Gajdács, M, Galali, Y, Gallus, S, Gandhi, A, Ganesan, B, Ganiyani, M, Garcia, V, Gardner, W, Garg, R, Gautam, R, Gebi, T, Gebregergis, M, Gebrehiwot, M, Gebremariam, T, Gebremeskel, T, Gerema, U, Getacher, L, Getahun, G, Getie, M, Ghadirian, F, Ghafarian, S, Ghaffari Jolfayi, A, Ghailan, K, Ghajar, A, Ghasemi, M, Ghasempour Dabaghi, G, Ghasemzadeh, A, Ghassemi, F, Ghazy, R, Gholami, A, Gholamrezanezhad, A, Gholizadeh, N, Ghorbani, M, Gil, A, Gil, G, Gilbertson, N, Gill, P, Gill, T, Gindaba, E, Girmay, A, Glasbey, J, Gnedovskaya, E, Göbölös, L, Godinho, M, Goel, A, Golechha, M, Goleij, P, Golinelli, D, Gomes, N, Gopalani, S, Gorini, G, Goudarzi, H, Goulart, A, Gouravani, M, Goyal, A, Graham, S, Grivna, M, Grosso, G, Guan, S, Guarducci, G, Gubari, M, Guha, A, Guicciardi, S, Gulati, S, Gulisashvili, D, Gunawardane, D, Guo, C, Gupta, A, Gupta, B, Gupta, M, Gupta, R, Gupta, S, Gupta, V, Habibzadeh, F, Habibzadeh, P, Hadaro, T, Hadian, Z, Haep, N, Haghi-Aminjan, H, Haghmorad, D, Hagins, H, Haile, D, Hailu, A, Hajj Ali, A, Halboub, E, Halimi, A, Hall, B, Haller, S, Halwani, R, Hamadeh, R, Hamdy, N, Hameed, S, Hamidi, S, Hammoud, A, Hanif, A, Hanifi, N, Haq, Z, Haque, M, Harapan, H, Hargono, A, Haro, J, Hasaballah, A, Hasan, I, Hasan, M, Hasan, S, Hasani, H, Hasanian, M, Hashmeh, N, Hasnain, M, Hassan, A, Hassan, I, Hassan Zadeh Tabatabaei, M, Hassani, S, Hassanipour, S, Hassankhani, H, Haubold, J, Havmoeller, R, Hay, S, Hebert, J, Hegazi, O, Hegena, T, Heidari, G, Heidari, M, Helfer, B, Hemmati, M, Henson, C, Herbert, M, Herteliu, C, Heuer, A, Hezam, K, Hinneh, T, Hiraike, Y, Hoan, N, Holla, R, Hon, J, Hoque, M, Horita, N, Hossain, S, Hosseini, S, Hosseinzadeh, H, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Hoven, H, Hsairi, M, Hsu, J, Hu, C, Huang, J, Huda, M, Hulland, E, Hultström, M, Hushmandi, K, Hussain, J, Hussein, N, Huynh, C, Huynh, H, Ibitoye, S, Idowu, O, Ihler, A, Ikeda, N, Ikuta, K, Ilesanmi, O, Ilic, I, Ilic, M, Imam, M, Immurana, M, Inbaraj, L, Irham, L, Isa, M, Islam, M, Ismail, F, Ismail, N, Iso, H, Isola, G, Iwagami, M, Iwu, C, Iwu-Jaja, C, J, V, Jaafari, J, Jacob, L, Jacobsen, K, Jadidi-Niaragh, F, Jahankhani, K, Jahanmehr, N, Jahrami, H, Jain, A, Jain, N, Jairoun, A, Jaiswal, A, Jakovljevic, M, Jalilzadeh Yengejeh, R, Jamora, R, Jatau, A, Javadov, S, Javaheri, T, Jayaram, S, Jeganathan, J, Jeswani, B, Jiang, H, Johnson, C, Jokar, M, Jomehzadeh, N, Jonas, J, Joo, T, Joseph, A, Joseph, N, Joshi, V, Joshua, C, Jozwiak, J, Jürisson, M, Kaambwa, B, Kabir, A, Kabir, Z, Kadashetti, V, Kahn, E, Kalani, R, Kaliyadan, F, Kalra, S, Kamath, R, Kanagasabai, T, Kanchan, T, Kandel, H, Kanmiki, E, Kanmodi, K, Kansal, S, Kapner, D, Kapoor, N, Karagiannidis, E, Karajizadeh, M, Karakasis, P, Karanth, S, Karaye, I, Karch, A, Karim, A, Karimi, H, Karmakar, S, Kashoo, F, Kasraei, H, Kassahun, W, Kassebaum, N, Kassel, M, Katikireddi, S, Kauppila, J, Kawakami, N, Kaydi, N, Kayode, G, Kazemi, F, Keiyoro, P, Kemmer, L, Kempen, J, Kerr, J, Kesse-Guyot, E, Khader, Y, Khafaie, M, Khajuria, H, Khalaji, A, Khalil, M, Khalilian, A, Khamesipour, F, Khan, A, Khan, M, Khanmohammadi, S, Khatab, K, Khatatbeh, H, Khatatbeh, M, Khatib, M, Khavandegar, A, Khayat Kashani, H, Khidri, F, Khodadoust, E, Khormali, M, Khorrami, Z, Khosla, A, Khosrowjerdi, M, Khreis, H, Khusun, H, Kifle, Z, Kim, K, Kim, M, Kim, Y, Kimokoti, R, Kisa, A, Kisa, S, Knibbs, L, Knudsen, A, Koh, D, Kolahi, A, Kompani, F, Kong, J, Koren, G, Korja, M, Korshunov, V, Korzh, O, Kosen, S, Kothari, N, Koul, P, Koulmane Laxminarayana, S, Krishan, K, Krishnamoorthy, V, Krishnamoorthy, Y, Krishnan, B, Krohn, K, Kuate Defo, B, Kucuk Bicer, B, Kuddus, M, Kugbey, N, Kuitunen, I, Kulimbet, M, Kulkarni, V, Kumar, A, Kumar, N, Kumar, V, Kundu, S, Kurmi, O, Kusnali, A, Kusuma, D, Kutluk, T, La Vecchia, C, Ladan, M, Laflamme, L, Lahariya, C, Lai, D, Lal, D, Lallukka, T, Lám, J, Lan, Q, Lan, T, Landires, I, Lanfranchi, F, Langguth, B, Lansingh, V, Laplante-Lévesque, A, Larijani, B, Larsson, A, Lasrado, S, Lauriola, P, Le, H, Le, L, Le, N, Le, T, Leasher, J, Ledda, C, Lee, M, Lee, P, Lee, S, Lee, Y, Legrand, K, Leigh, J, Leong, E, Lerango, T, Lescinsky, H, Leung, J, Li, M, Li, W, Li, Y, Li, Z, Ligade, V, Lim, L, Lim, S, Lin, R, Lin, S, Liu, C, Liu, G, Liu, J, Liu, R, Liu, S, Liu, W, Liu, X, Livingstone, K, Llanaj, E, Lohiya, A, López-Bueno, R, Lopukhov, P, Lorkowski, S, Lotufo, P, Lozano, R, Lubinda, J, Lucchetti, G, Luo, L, Lv, H, M Amin, H, Ma, Z, Maass, K, Mabrok, M, Machairas, N, Machoy, M, Mafhoumi, A, Magdy Abd El Razek, M, Maghazachi, A, Mahadeshwara Prasad, D, Maharaj, S, Mahmoud, M, Mahmoudi, E, Majeed, A, Makram, O, Makris, K, Malasala, S, Maled, V, Malhotra, K, Malik, A, Malik, I, Malinga, L, Malta, D, Mamun, A, Manda, A, Manla, Y, Mansour, A, Mansouri, B, Mansouri, P, Mansourian, M, Mansournia, M, Mantovani, L, Manu, E, Marateb, H, Maravilla, J, Marsh, E, Martinez, G, Martinez-Piedra, R, Martini, S, Martins-Melo, F, Martorell, M, Marx, W, Maryam, S, Mathangasinghe, Y, Mathioudakis, A, Matozinhos, F, Mattumpuram, J, Maugeri, A, Maulik, P, Mayeli, M, Mazidi, M, Mazzotti, A, Mcgrath, J, Mckee, M, Mckowen, A, Mclaughlin, S, Mcphail, M, Mcphail, S, Mechili, E, Mehmood, A, Mehmood, K, Mehrabani-Zeinabad, K, Mehrabi Nasab, E, Meier, T, Mejia-Rodriguez, F, Mekene Meto, T, Mekonnen, B, Menezes, R, Mengist, B, Mensah, G, Mensah, L, Mentis, A, Meo, S, Meretoja, A, Meretoja, T, Mersha, A, Mesfin, B, Mestrovic, T, Mettananda, K, Mettananda, S, Miazgowski, T, Micha, G, Michalek, I, Micheletti Gomide Nogueira de Sá, A, Miller, T, Mirarefin, M, Mirghafourvand, M, Mirica, A, Mirijello, A, Mirrakhimov, E, Mirshahi, A, Mirzaei, M, Mishra, A, Mishra, V, Mitchell, P, Mithra, P, Mittal, C, Moazen, B, Moberg, M, Mocciaro, G, Mohamadkhani, A, Mohamed, A, Mohamed, J, Mohamed, M, Mohamed, N, Mohammadi, E, Mohammadi, S, Mohammadian-Hafshejani, A, Mohammadifard, N, Mohammed, H, Mohammed, M, Mohammed, S, Mokdad, A, Monasta, L, Mondello, S, Moni, M, Moodi Ghalibaf, A, Moore, C, Moradi, M, Moradi, Y, Moraga, P, Morawska, L, Moreira, R, Morovatdar, N, Morrison, S, Morze, J, Mosaddeghi Heris, R, Mossialos, E, Motappa, R, Mougin, V, Mousavi, P, Msherghi, A, Mubarik, S, Muccioli, L, Mueller, U, Mulita, F, Mullany, E, Munjal, K, Murillo-Zamora, E, Murlimanju, B, Musina, A, Mustafa, G, Muthu, S, Muthupandian, S, Muthusamy, R, Muzaffar, M, Myung, W, Nafei, A, Nagarajan, A, Nagaraju, S, Nagel, G, Naghavi, M, Naghavi, P, Naik, G, Nainu, F, Nair, T, Najdaghi, S, Nakhostin Ansari, N, Nanavaty, D, Nangia, V, Narasimha Swamy, S, Narimani Davani, D, Nascimento, B, Nascimento, G, Nashwan, A, Natto, Z, Nauman, J, Navaratna, S, Naveed, M, Nayak, B, Nayak, V, Ndejjo, R, Nduaguba, S, Negash, H, Negoi, I, Negoi, R, Nejadghaderi, S, Nejjari, C, Nematollahi, M, Nepal, S, Neupane, S, Ng, M, Nguefack-Tsague, G, Ngunjiri, J, Nguyen, D, Nguyen, N, Nguyen, P, Nguyen, V, Nguyen Tran Minh, D, Niazi, R, Nicholson, S, Nie, J, Nikoobar, A, Nikpoor, A, Ningrum, D, Nnaji, C, Noman, E, Nomura, S, Noroozi, N, Norrving, B, Noubiap, J, Nri-Ezedi, C, Ntaios, G, Ntsekhe, M, Nunemo, M, Nurrika, D, Nutor, J, Oancea, B, O'Connell, E, Odetokun, I, O'Donnell, M, Oduro, M, Ogunfowokan, A, Ogunkoya, A, Oh, I, Okati-Aliabad, H, Okeke, S, Okekunle, A, Okonji, O, Olagunju, A, Olasupo, O, Olatubi, M, Oliveira, A, Oliveira, G, Olorukooba, A, Olufadewa, I, Olusanya, B, Olusanya, J, Oluwafemi, Y, Omar, H, Omar Bali, A, Omer, G, Ong, K, Ong, S, Onwujekwe, O, Onyedibe, K, Oppong, A, Ordak, M, Orish, V, Ornello, R, Orpana, H, Ortiz, A, Ortiz-Prado, E, Osman, W, Ostroff, S, Osuagwu, U, Otoiu, A, Otstavnov, N, Otstavnov, S, Ouyahia, A, Owolabi, M, Oyeyemi, I, Oyeyemi, O, P A, M, Pacheco-Barrios, K, Padron-Monedero, A, Padubidri, J, Pal, P, Palicz, T, Pan, F, Pan, H, Pana, A, Panda, S, Panda-Jonas, S, Pandey, A, Pandi-Perumal, S, Pangaribuan, H, Pantazopoulos, I, Pantea Stoian, A, Papadopoulou, P, Parent, M, Parija, P, Parikh, R, Park, S, Parsons, N, Pashaei, A, Pasovic, M, Passera, R, Patil, S, Patoulias, D, Patthipati, V, Paudel, U, Pawar, S, Pazoki Toroudi, H, Peden, A, Pedersini, P, Peng, M, Pensato, U, Pepito, V, Peprah, E, Peprah, P, Peres, M, Perianayagam, A, Perico, N, Perna, S, Pesudovs, K, Petcu, I, Petermann-Rocha, F, Pham, H, Philip, A, Phillips, M, Pickering, B, Pierannunzio, D, Pigeolet, M, Pigott, D, Piracha, Z, Piradov, M, Pisoni, E, Piyasena, M, Plass, D, Plotnikov, E, Poddighe, D, Polkinghorne, K, Poluru, R, Pond, C, Popovic, D, Porru, F, Postma, M, Poudel, G, Pour-Rashidi, A, Pourshams, A, Pourtaheri, N, Prabhu, D, Prada, S, Pradhan, J, Pradhan, P, Prasad, M, Prates, E, Purnobasuki, H, Purohit, B, Puvvula, J, Qasim, N, Qattea, I, Qazi, A, Qian, G, Qiu, S, Rabiee Rad, M, Radfar, A, Radhakrishnan, R, Radhakrishnan, V, Raeisi Shahraki, H, Rafferty, Q, Rafiei, A, Raggi, A, Raghav, P, Raheem, N, Rahim, F, Rahim, M, Rahimifard, M, Rahimi-Movaghar, V, Rahman, M, Rahmani, A, Rahmani, B, Rahmanian, M, Rahmanian, N, Rahmanian, V, Rahmati, M, Rahmawaty, S, Raimondo, D, Rajaa, S, Rajendran, V, Rajput, P, Ramadan, M, Ramasamy, S, Ramasubramani, P, Ramazanu, S, Ramteke, P, Rana, J, Rana, K, Ranabhat, C, Rane, A, Rani, U, Ranta, A, Rao, C, Rao, M, Rao, P, Rao, S, Rasella, D, Rashedi, S, Rashedi, V, Rashidi, M, Rasouli-Saravani, A, Ratan, Z, Rathnaiah Babu, G, Rauniyar, S, Rautalin, I, Rawaf, D, Rawaf, S, Rawassizadeh, R, Razo, C, Reda, Z, Reddy, M, Redwan, E, Reifels, L, Reitsma, M, Remuzzi, G, Reshmi, B, Resnikoff, S, Restaino, S, Reyes, L, Rezaei, M, Rezaei, N, Rezaeian, M, Rhee, T, Riaz, M, Ribeiro, A, Rickard, J, Robinson-Oden, H, Rodrigues, C, Rodrigues, M, Rodriguez, J, Roever, L, Romadlon, D, Ronfani, L, Rosauer, J, Roshandel, G, Rostamian, M, Rotimi, K, Rout, H, Roy, B, Roy, N, Rubagotti, E, Ruela, G, Rumisha, S, Runghien, T, Russo, M, Ruzzante, S, S N, C, Saad, A, Saber, K, Saber-Ayad, M, Sabour, S, Sacco, S, Sachdev, P, Sachdeva, R, Saddik, B, Saddler, A, Sadee, B, Sadeghi, E, Sadeghi, M, Sadeghi Majd, E, Saeb, M, Saeed, U, Safari, M, Safi, S, Sagar, R, Sagoe, D, Saheb Sharif-Askari, F, Saheb Sharif-Askari, N, Sahebkar, A, Sahoo, S, Sahu, M, Saif, Z, Sajid, M, Sakshaug, J, Salam, N, Salamati, P, Salami, A, Salaroli, L, Salehi, L, Salehi, S, Salem, M, Salihu, D, Salimi, S, Salum, G, Samadi Kafil, H, Samadzadeh, S, Samodra, Y, Samuel, V, Samy, A, Sanabria, J, Sanjeev, R, Sanna, F, Santomauro, D, Santric-Milicevic, M, Sarasmita, M, Saraswathy, S, Saravanan, A, Saravi, B, Sarikhani, Y, Sarmiento-Suárez, R, Sarode, G, Sarode, S, Sartorius, B, Sarveazad, A, Sathian, B, Sattin, D, Sawhney, M, Saya, G, Sayeed, A, Sayeed, M, Sayyah, M, Schinckus, C, Schmidt, M, Schuermans, A, Schumacher, A, Schutte, A, Schwarzinger, M, Schwebel, D, Schwendicke, F, Selvaraj, S, Semreen, M, Senthilkumaran, S, Serban, D, Serre, M, Sethi, Y, Shafie, M, Shah, H, Shah, N, Shah, P, Shah, S, Shahbandi, A, Shaheen, A, Shahid, S, Shahid, W, Shahsavari, H, Shahwan, M, Shaikh, M, Shaikh, S, Shalash, A, Sham, S, Shamim, M, Shams-Beyranvand, M, Shamshirgaran, M, Shamsi, M, Shanawaz, M, Shankar, A, Sharfaei, S, Sharifan, A, Sharifi-Rad, J, Sharma, M, Sharma, U, Sharma, V, Shastry, R, Shavandi, A, Shehabeldine, A, Shehzadi, S, Sheikh, A, Shen, J, Shetty, A, Shetty, B, Shetty, P, Shiani, A, Shiferaw, D, Shigematsu, M, Shin, M, Shiri, R, Shittu, A, Shiue, I, Shivakumar, K, Shivarov, V, Shool, S, Shorofi, S, Shrestha, R, Shrestha, S, Shuja, K, Shuval, K, Si, Y, Siddig, E, Silva, D, Silva, L, Silva, S, Silva, T, Simpson, C, Singh, A, Singh, B, Singh, G, Singh, H, Singh, J, Singh, M, Singh, N, Singh, P, Singh, S, Sinto, R, Sivakumar, S, Siwal, S, Skhvitaridze, N, Skou, S, Sleet, D, Sobia, F, Soboka, M, Socea, B, Solaimanian, S, Solanki, R, Solanki, S, Soliman, S, Somayaji, R, Song, Y, Sorensen, R, Soriano, J, Soyiri, I, Spartalis, M, Spearman, S, Spencer, C, Sreeramareddy, C, Stachteas, P, Stafford, L, Stanaway, J, Stanikzai, M, Stein, C, Stein, D, Steinbeis, F, Steiner, C, Steinke, S, Steiropoulos, P, Stockfelt, L, Stokes, M, Straif, K, Stranges, S, Subedi, N, Subramaniyan, V, Suleman, M, Suliankatchi Abdulkader, R, Sundström, J, Sunkersing, D, Sunnerhagen, K, Suresh, V, Swain, C, Szarpak, L, Szeto, M, Tabaee Damavandi, P, Tabarés-Seisdedos, R, Tabatabaei, S, Tabatabaei Malazy, O, Tabatabaeizadeh, S, Tabatabai, S, Tabche, C, Tabish, M, Tadakamadla, S, Taheri Abkenar, Y, Taheri Soodejani, M, Taherkhani, A, Taiba, J, Takahashi, K, Talaat, I, Tamuzi, J, Tan, K, Tang, H, Tat, N, Taveira, N, Tefera, Y, Tehrani-Banihashemi, A, Temesgen, W, Temsah, M, Teramoto, M, Terefa, D, Teye-Kwadjo, E, Thakur, R, Thangaraju, P, Thankappan, K, Thapar, R, Thayakaran, R, Thirunavukkarasu, S, Thomas, N, Tian, J, Tichopad, A, Ticoalu, J, Tiruye, T, Tobe-Gai, R, Tolani, M, Tolossa, T, Tonelli, M, Topor-Madry, R, Topouzis, F, Touvier, M, Tovani-Palone, M, Trabelsi, K, Tran, J, Tran, M, Tran, N, Trico, D, Trihandini, I, Troeger, C, Tromans, S, Truyen, T, Tsatsakis, A, Tsermpini, E, Tumurkhuu, M, Udoakang, A, Udoh, A, Ullah, A, Ullah, S, Umair, M, Umakanthan, S, Unim, B, Unnikrishnan, B, Upadhyay, E, Urso, D, Usman, J, Vaithinathan, A, Vakili, O, Valenti, M, Valizadeh, R, Van den Eynde, J, van Donkelaar, A, Varga, O, Vart, P, Varthya, S, Vasankari, T, Vasic, M, Vaziri, S, Venketasubramanian, N, Verghese, N, Verma, M, Veroux, M, Verras, G, Vervoort, D, Villafañe, J, Villalobos-Daniel, V, Villani, L, Villanueva, G, Vinayak, M, Violante, F, Vlassov, V, Vo, B, Vollset, S, Volovat, S, Vos, T, Vujcic, I, Waheed, Y, Wang, C, Wang, F, Wang, S, Wang, Y, Wanjau, M, Waqas, M, Ward, P, Waris, A, Wassie, E, Weerakoon, K, Weintraub, R, Weiss, D, Weiss, E, Weldetinsaa, H, Wells, K, Wen, Y, Wiangkham, T, Wickramasinghe, N, Wilkerson, C, Willeit, P, Wilson, S, Wong, Y, Wongsin, U, Wozniak, S, Wu, C, Wu, D, Wu, F, Wu, Z, Xia, J, Xiao, H, Xu, S, Xu, X, Xu, Y, Yadav, M, Yaghoubi, S, Yamagishi, K, Yang, L, Yano, Y, Yaribeygi, H, Yasufuku, Y, Ye, P, Yesodharan, R, Yesuf, S, Yezli, S, Yi, S, Yiğit, A, Yigzaw, Z, Yin, D, Yip, P, Yismaw, M, Yon, D, Yonemoto, N, You, Y, Younis, M, Yousefi, Z, Yu, C, Yu, Y, Zadey, S, Zadnik, V, Zakham, F, Zaki, N, Zakzuk, J, Zamagni, G, Zaman, S, Zandieh, G, Zanghì, A, Zar, H, Zare, I, Zarimeidani, F, Zastrozhin, M, Zeng, Y, Zhai, C, Zhang, A, Zhang, H, Zhang, L, Zhang, M, Zhang, Y, Zhang, Z, Zhao, H, Zhao, J, Zhao, X, Zhao, Y, Zhong, C, Zhou, J, Zhou, S, Zhu, B, Zhu, L, Zhu, Z, Ziaeian, B, Ziafati, M, Zielińska, M, Zimsen, S, Zoghi, G, Zoller, T, Zumla, A, Zyoud, S, Murray, C, Gakidou, E, Brauer, Michael, Roth, Gregory A, Aravkin, Aleksandr Y, Zheng, Peng, Abate, Kalkidan Hassen, Abate, Yohannes Habtegiorgis, Abbafati, Cristiana, Abbasgholizadeh, Rouzbeh, Abbasi, Madineh Akram, Abbasian, Mohammadreza, Abbasifard, Mitra, Abbasi-Kangevari, Mohsen, Abd ElHafeez, Samar, Abd-Elsalam, Sherief, Abdi, Parsa, Abdollahi, Mohammad, Abdoun, Meriem, Abdulah, Deldar Morad, Abdullahi, Auwal, Abebe, Mesfin, Abedi, Aidin, Abedi, Armita, Abegaz, Tadesse M, Abeldaño Zuñiga, Roberto Ariel, Abiodun, Olumide, Abiso, Temesgen Lera, Aboagye, Richard Gyan, Abolhassani, Hassan, Abouzid, Mohamed, Aboye, Girma Beressa, Abreu, Lucas Guimarães, Abualruz, Hasan, Abubakar, Bilyaminu, Abu-Gharbieh, Eman, Abukhadijah, Hana Jihad Jihad, Aburuz, Salahdein, Abu-Zaid, Ahmed, Adane, Mesafint Molla, Addo, Isaac Yeboah, Addolorato, Giovanni, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Aden, Bashir, Adetunji, Juliana Bunmi, Adeyeoluwa, Temitayo Esther, Adha, Rishan, Adibi, Amin, Adnani, Qorinah Estiningtyas Sakilah, Adzigbli, Leticia Akua, Afolabi, Aanuoluwapo Adeyimika, Afolabi, Rotimi Felix, Afshin, Ashkan, Afyouni, Shadi, Afzal, Muhammad Sohail, Afzal, Saira, Agampodi, Suneth Buddhika, Agbozo, Faith, Aghamiri, Shahin, Agodi, Antonella, Agrawal, Anurag, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahmad, Aqeel, Ahmad, Danish, Ahmad, Firdos, Ahmad, Noah, Ahmad, Shahzaib, Ahmad, Tauseef, Ahmed, Ali, Ahmed, Anisuddin, Ahmed, Ayman, Ahmed, Luai A, Ahmed, Muktar Beshir, Ahmed, Safoora, Ahmed, Syed Anees, Ajami, Marjan, Akalu, Gizachew Taddesse, Akara, Essona Matatom, Akbarialiabad, Hossein, Akhlaghi, Shiva, Akinosoglou, Karolina, Akinyemiju, Tomi, Akkaif, Mohammed Ahmed, Akkala, Sreelatha, Akombi-Inyang, Blessing, Al Awaidy, Salah, Al Hasan, Syed Mahfuz, Alahdab, Fares, AL-Ahdal, Tareq Mohammed Ali, Alalalmeh, Samer O, Alalwan, Tariq A, Al-Aly, Ziyad, Alam, Khurshid, Alam, Nazmul, Alanezi, Fahad Mashhour, Alanzi, Turki M, Albakri, Almaza, AlBataineh, Mohammad T, Aldhaleei, Wafa A, Aldridge, Robert W, Alemayohu, Mulubirhan Assefa, Alemu, Yihun Mulugeta, Al-Fatly, Bassam, Al-Gheethi, Adel Ali Saeed, Al-Habbal, Khairat, Alhabib, Khalid F, Alhassan, Robert Kaba, Ali, Abid, Ali, Amjad, Ali, Beriwan Abdulqadir, Ali, Iman, Ali, Liaqat, Ali, Mohammed Usman, Ali, Rafat, Ali, Syed Shujait Shujait, Ali, Waad, Alicandro, Gianfranco, Alif, Sheikh Mohammad, Aljunid, Syed Mohamed, Alla, François, Al-Marwani, Sabah, Al-Mekhlafi, Hesham M, Almustanyir, Sami, Alomari, Mahmoud A, Alonso, Jordi, Alqahtani, Jaber S, Alqutaibi, Ahmed Yaseen, Al-Raddadi, Rajaa M, Alrawashdeh, Ahmad, Al-Rifai, Rami Hani, Alrousan, Sahel Majed, Al-Sabah, Salman Khalifah, Alshahrani, Najim Z, Altaany, Zaid, Altaf, Awais, Al-Tawfiq, Jaffar A, Altirkawi, Khalid A, Aluh, Deborah Oyine, Alvis-Guzman, Nelson, Alvis-Zakzuk, Nelson J, Alwafi, Hassan, Al-Wardat, Mohammad Sami, Al-Worafi, Yaser Mohammed, Aly, Hany, Aly, Safwat, Alzoubi, Karem H, Al-Zyoud, Walid, Amaechi, Uchenna Anderson, Aman Mohammadi, Masous, Amani, Reza, Amiri, Sohrab, Amirzade-Iranaq, Mohammad Hosein, Ammirati, Enrico, Amu, Hubert, Amugsi, Dickson A, Amusa, Ganiyu Adeniyi, Ancuceanu, Robert, Anderlini, Deanna, Anderson, Jason A, Andrade, Pedro Prata, Andrei, Catalina Liliana, Andrei, Tudorel, Anenberg, Susan C, 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Catalá-López, Ferrán, Catapano, Alberico L, Cattaruzza, Maria Sofia, Caye, Arthur, Cederroth, Christopher R, Cegolon, Luca, Cenderadewi, Muthia, Cercy, Kelly M, Cerin, Ester, Chadwick, Joshua, Chakraborty, Chiranjib, Chakraborty, Promit Ananyo, Chakraborty, Sandip, Chan, Jeffrey Shi Kai, Chan, Raymond N C, Chandan, Joht Singh, Chandika, Rama Mohan, Chaturvedi, Pankaj, Chen, An-Tian, Chen, Catherine S, Chen, Haowei, Chen, Meng Xuan, Chen, Mingling, Chen, Simiao, Cheng, Ching-Yu, Cheng, Esther T W, Cherbuin, Nicolas, Chi, Gerald, Chichagi, Fatemeh, Chimed-Ochir, Odgerel, Chimoriya, Ritesh, Ching, Patrick R, Chirinos-Caceres, Jesus Lorenzo, Chitheer, Abdulaal, Cho, William C S, Chong, Bryan, Chopra, Hitesh, Chowdhury, Rajiv, Christopher, Devasahayam J, Chu, Dinh-Toi, Chukwu, Isaac Sunday, Chung, Eric, Chung, Sheng-Chia, Chutiyami, Muhammad, Cioffi, Iolanda, Cogen, Rebecca M, Cohen, Aaron J, Columbus, Alyssa, Conde, Joao, Corlateanu, Alexandru, Cortese, Samuele, Cortesi, Paolo Angelo, Costa, Vera Marisa, Costanzo, Simona, Criqui, Michael H, Cruz, Jessica A, Cruz-Martins, Natália, Culbreth, Garland T, da Silva, Alanna Gomes, Dadras, Omid, Dai, Xiaochen, Dai, Zhaoli, Daikwo, Patience Unekwuojo, Dalli, Lachlan L, Damiani, Giovanni, D'Amico, Emanuele, D'Anna, Lucio, Darwesh, Aso Mohammad, Das, Jai K, Das, Subasish, Dash, Nihar Ranjan, Dashti, Mohsen, Dávila-Cervantes, Claudio Alberto, Davis Weaver, Nicole, Davitoiu, Dragos Virgil, De la Hoz, Fernando Pio, de la Torre-Luque, Alejandro, De Leo, Diego, Debopadhaya, Shayom, Degenhardt, Louisa, Del Bo', Cristian, Delgado-Enciso, Ivan, Delgado-Saborit, Juana Maria, Demoze, Chalachew Kassaw, Denova-Gutiérrez, Edgar, Dervenis, Nikolaos, Dervišević, Emina, Desai, Hardik Dineshbhai, Desai, Rupak, Devanbu, Vinoth Gnana Chellaiyan, Dewan, Syed Masudur Rahman, Dhali, Arkadeep, Dhama, Kuldeep, Dhane, Amol S, Dhimal, Mandira Lamichhane, Dhimal, Meghnath, Dhingra, Sameer, Dhulipala, Vishal R, Dhungana, Raja Ram, Dias da Silva, Diana, Diaz, Daniel, Diaz, Luis Antonio, Diaz, Michael J, Dima, Adriana, Ding, Delaney D, Dinu, Monica, Djalalinia, Shirin, Do, Thanh Chi, Do, Thao Huynh Phuong, do Prado, Camila Bruneli, Dodangeh, Masoud, Dohare, Sushil, Dokova, Klara Georgieva, Dong, Wanyue, Dongarwar, Deepa, D'Oria, Mario, Dorostkar, Fariba, Dorsey, E Ray, Doshi, Rajkumar, Doshmangir, Leila, Dowou, Robert Kokou, Driscoll, Tim Robert, Dsouza, Ashel Chelsea, Dsouza, Haneil Larson, Dumith, Samuel C, Duncan, Bruce B, Duraes, Andre Rodrigues, Duraisamy, Senbagam, Dushpanova, Anar, Dzianach, Paulina Agnieszka, Dziedzic, Arkadiusz Marian, Ebrahimi, Alireza, Echieh, Chidiebere Peter, Ed-Dra, Abdelaziz, Edinur, Hisham Atan, Edvardsson, David, Edvardsson, Kristina, Efendi, Ferry, Eftekharimehrabad, Aziz, Eini, Ebrahim, Ekholuenetale, Michael, Ekundayo, Temitope Cyrus, El Arab, Rabie Adel, El Sayed Zaki, Maysaa, El-Dahiyat, Faris, Elemam, Noha Mousaad, Elgar, Frank J, ElGohary, Ghada Metwally Tawfik, Elhabashy, Hala Rashad, Elhadi, Muhammed, Elmehrath, Ahmed O, Elmeligy, Omar Abdelsadek Abdou, Elshaer, Mohammed, Elsohaby, Ibrahim, Emeto, Theophilus I, Esfandiari, Negin, Eshrati, Babak, Eslami, Majid, Esmaeili, Sayed Vahid, Estep, Kara, Etaee, Farshid, Fabin, Natalia, Fagbamigbe, Adeniyi Francis, Fagbule, Omotayo Francis, Fahimi, Saman, Falzone, Luca, Fareed, Mohammad, Farinha, Carla Sofia e Sá, Faris, MoezAlIslam Ezzat Mahmoud, Faris, Pawan Sirwan, Faro, Andre, Fasina, Folorunso Oludayo, Fatehizadeh, Ali, Fauk, Nelsensius Klau, Fazylov, Timur, Feigin, Valery L, Feng, Xiaoqi, Fereshtehnejad, Seyed-Mohammad, Feroze, Abdullah Hamid, Ferrara, Pietro, Ferrari, Alize J, Ferreira, Nuno, Fetensa, Getahun, Feyisa, Bikila Regassa, Filip, Irina, Fischer, Florian, Fitriana, Ida, Flavel, Joanne, Flohr, Carsten, Flood, David, Flor, Luisa S, Foigt, Nataliya A, Folayan, Morenike Oluwatoyin, Force, Lisa M, Fortuna, Daniela, Foschi, Matteo, Franklin, Richard Charles, Freitas, Alberto, Friedman, Sara D, Fux, Blima, G, Sridevi, Gaal, Peter Andras, Gaihre, Santosh, Gajdács, Márió, Galali, Yaseen, Gallus, Silvano, Gandhi, Aravind P, Ganesan, Balasankar, Ganiyani, Mohammad Arfat, Garcia, Vanessa, Gardner, William M, Garg, Ravindra K, Gautam, Rupesh K, Gebi, Tilaye Gebru, Gebregergis, Miglas W, Gebrehiwot, Mesfin, Gebremariam, Tesfay B B, Gebremeskel, Teferi Gebru, Gerema, Urge, Getacher, Lemma, Getahun, Genanew K a, Getie, Molla, Ghadirian, Fataneh, Ghafarian, Sadegh, Ghaffari Jolfayi, Amir, Ghailan, Khalid Yaser, Ghajar, Alireza, Ghasemi, MohammadReza, Ghasempour Dabaghi, Ghazal, Ghasemzadeh, Afsaneh, Ghassemi, Fariba, Ghazy, Ramy Mohamed, Gholami, Ali, Gholamrezanezhad, Ali, Gholizadeh, Nasim, Ghorbani, Mahsa, Gil, Artyom Urievich, Gil, Gabriela Fernanda, Gilbertson, Nora M, Gill, Paramjit Singh, Gill, Tiffany K, Gindaba, Ebisa Zerihun, Girmay, Alem, Glasbey, James C, Gnedovskaya, Elena V, Göbölös, Laszlo, Godinho, Myron Anthony, Goel, Amit, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Gomes, Nelson G M, Gopalani, Sameer Vali, Gorini, Giuseppe, Goudarzi, Houman, Goulart, Alessandra C, Gouravani, Mahdi, Goyal, Anmol, Graham, Simon Matthew, Grivna, Michal, Grosso, Giuseppe, Guan, Shi-Yang, Guarducci, Giovanni, Gubari, Mohammed Ibrahim Mohialdeen, Guha, Avirup, Guicciardi, Stefano, Gulati, Snigdha, Gulisashvili, David, Gunawardane, Damitha Asanga, Guo, Cui, Gupta, Anish Kumar, Gupta, Bhawna, Gupta, Mohak, Gupta, Rahul, Gupta, Rajat Das, Gupta, Rajeev, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vijai Kumar, Gupta, Vivek Kumar, Habibzadeh, Farrokh, Habibzadeh, Parham, Hadaro, Tesfahun Simon, Hadian, Zahra, Haep, Nils, Haghi-Aminjan, Hamed, Haghmorad, Dariush, Hagins, Hailey, Haile, Demewoz, Hailu, Alemayehu, Hajj Ali, Adel, Halboub, Esam S, Halimi, Aram, Hall, Brian J, Haller, Sebastian, Halwani, Rabih, Hamadeh, Randah R, Hamdy, Nadia M, Hameed, Sajid, Hamidi, Samer, Hammoud, Ahmad, Hanif, Asif, Hanifi, Nasrin, Haq, Zaim Anan, Haque, Md Rabiul, Harapan, Harapan, Hargono, Arief, Haro, Josep Maria, Hasaballah, Ahmed I, Hasan, Ikramul, Hasan, Mohammad Jahid, Hasan, S M Mahmudul, Hasani, Hamidreza, Hasanian, Mohammad, Hashmeh, Nadim, Hasnain, Md Saquib, Hassan, Amr, Hassan, Ikrama, Hassan Zadeh Tabatabaei, Mahgol Sadat, Hassani, Shokoufeh, Hassanipour, Soheil, Hassankhani, Hadi, Haubold, Johannes, Havmoeller, Rasmus J, Hay, Simon I, Hebert, Jeffrey J, Hegazi, Omar E, Hegena, Tadele Yohannes, Heidari, Golnaz, Heidari, Mohammad, Helfer, Bartosz, Hemmati, Mehdi, Henson, Claire A, Herbert, Molly E, Herteliu, Claudiu, Heuer, Austin, Hezam, Kamal, Hinneh, Thomas Kwadwo, Hiraike, Yuta, Hoan, Nguyen Quoc, Holla, Ramesh, Hon, Julia, Hoque, Mohammad Enamul, Horita, Nobuyuki, Hossain, Sahadat, Hosseini, Seyed Ehsan, Hosseinzadeh, Hassan, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Hoven, Hanno, Hsairi, Mohamed, Hsu, Johnathan M, Hu, Chengxi, Huang, Junjie, Huda, Md Nazmul, Hulland, Erin N, Hultström, Michael, Hushmandi, Kiavash, Hussain, Javid, Hussein, Nawfal R, Huynh, Chantal K, Huynh, Hong-Han, Ibitoye, Segun Emmanuel, Idowu, Oluwatope Olaniyi, Ihler, Audrey L, Ikeda, Nayu, Ikuta, Kevin S, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Imam, Mohammad Tarique, Immurana, Mustapha, Inbaraj, Leeberk Raja, Irham, Lalu Muhammad, Isa, Mustafa Alhaji, Islam, Md Rabiul, Ismail, Faisal, Ismail, Nahlah Elkudssiah, Iso, Hiroyasu, Isola, Gaetano, Iwagami, Masao, Iwu, Chidozie C D, Iwu-Jaja, Chinwe Juliana, J, Vinothini, Jaafari, Jalil, Jacob, Louis, Jacobsen, Kathryn H, Jadidi-Niaragh, Farhad, Jahankhani, Kasra, Jahanmehr, Nader, Jahrami, Haitham, Jain, Akhil, Jain, Nityanand, Jairoun, Ammar Abdulrahman, Jaiswal, Abhishek, Jakovljevic, Mihajlo, Jalilzadeh Yengejeh, Reza, Jamora, Roland Dominic G, Jatau, Abubakar Ibrahim, Javadov, Sabzali, Javaheri, Tahereh, Jayaram, Shubha, Jeganathan, Jayakumar, Jeswani, Bijay Mukesh, Jiang, Heng, Johnson, Catherine O, Jokar, Mohammad, Jomehzadeh, Nabi, Jonas, Jost B, Joo, Tamas, Joseph, Abel, Joseph, Nitin, Joshi, 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Khalilian, Alireza, Khamesipour, Faham, Khan, Asaduzzaman, Khan, M Nuruzzaman, Khan, Maseer, Khan, Mohammad Jobair, Khan, Moien AB, Khanmohammadi, Shaghayegh, Khatab, Khaled, Khatatbeh, Haitham, Khatatbeh, Moawiah Mohammad, Khatib, Mahalaqua Nazli, Khavandegar, Armin, Khayat Kashani, Hamid Reza, Khidri, Feriha Fatima, Khodadoust, Elaheh, Khormali, Moein, Khorrami, Zahra, Khosla, Atulya Aman, Khosrowjerdi, Mahmood, Khreis, Haneen, Khusun, Helda, Kifle, Zemene Demelash, Kim, Kwanghyun, Kim, Min Seo, Kim, Yun Jin, Kimokoti, Ruth W, Kisa, Adnan, Kisa, Sezer, Knibbs, Luke D, Knudsen, Ann Kristin Skrindo, Koh, David S Q, Kolahi, Ali-Asghar, Kompani, Farzad, Kong, Jianqiu, Koren, Gerbrand, Korja, Miikka, Korshunov, Vladimir Andreevich, Korzh, Oleksii, Kosen, Soewarta, Kothari, Nikhil, Koul, Parvaiz A, Koulmane Laxminarayana, Sindhura Lakshmi, Krishan, Kewal, Krishnamoorthy, Vijay, Krishnamoorthy, Yuvaraj, Krishnan, Bindu, Krohn, Kris J, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kuddus, Md Abdul, Kuddus, Mohammed, Kugbey, Nuworza, Kuitunen, Ilari, Kulimbet, Mukhtar, Kulkarni, Vishnutheertha, Kumar, Ashish, Kumar, Nithin, Kumar, Vijay, Kundu, Satyajit, Kurmi, Om P, Kusnali, Asep, Kusuma, Dian, Kutluk, Tezer, La Vecchia, Carlo, Ladan, Muhammad Awwal, Laflamme, Lucie, Lahariya, Chandrakant, Lai, Daphne Teck Ching, Lal, Dharmesh Kumar, Lallukka, Tea, Lám, Judit, Lan, Qing, Lan, Tuo, Landires, Iván, Lanfranchi, Francesco, Langguth, Berthold, Lansingh, Van Charles, Laplante-Lévesque, Ariane, Larijani, Bagher, Larsson, Anders O, Lasrado, Savita, Lauriola, Paolo, Le, Huu-Hoai, Le, Long Khanh Dao, Le, Nhi Huu Hanh, Le, Thao Thi Thu, Leasher, Janet L, Ledda, Caterina, Lee, Munjae, Lee, Paul H, Lee, Seung Won, Lee, Shaun Wen Huey, Lee, Yo Han, LeGrand, Kate E, Leigh, James, Leong, Elvynna, Lerango, Temesgen L, Lescinsky, Haley, Leung, Janni, Li, Ming-Chieh, Li, Wang-Zhong, Li, Wei, Li, Yichong, Li, Zhihui, Ligade, Virendra S, Lim, Lee-Ling, Lim, Stephen S, Lin, Ro-Ting, Lin, Shuzhi, Liu, Chaojie, Liu, Gang, Liu, Jinli, Liu, Jue, Liu, Richard T, Liu, Shiwei, Liu, Wei, Liu, Xiaofeng, Liu, Xuefeng, Livingstone, Katherine M, Llanaj, Erand, Lohiya, Ayush, López-Bueno, Rubén, Lopukhov, Platon D, Lorkowski, Stefan, Lotufo, Paulo A, Lozano, Rafael, Lubinda, Jailos, Lucchetti, Giancarlo, Luo, Lisha, lv, Hengliang, M Amin, Hawraz Ibrahim, Ma, Zheng Feei, Maass, Kelsey Lynn, Mabrok, Mahmoud, Machairas, Nikolaos, Machoy, Monika, Mafhoumi, Asma, Magdy Abd El Razek, Mohammed, Maghazachi, Azzam A, Mahadeshwara Prasad, D R, Maharaj, Sandeep B, Mahmoud, Mansour Adam, Mahmoudi, Elham, Majeed, Azeem, Makram, Omar Mohamed, Makris, Konstantinos Christos, Malasala, Satyaveni, Maled, Venkatesh, Malhotra, Kashish, Malik, Ahmad Azam, Malik, Iram, Malinga, Lesibana Anthony, Malta, Deborah Carvalho, Mamun, Abdullah A, Manda, Ana Laura, Manla, Yosef, Mansour, Ali, Mansouri, Borhan, Mansouri, Pejman, Mansourian, Marjan, Mansournia, Mohammad Ali, Mantovani, Lorenzo Giovanni, Manu, Emmanuel, Marateb, Hamid Reza, Maravilla, Joemer C, Marsh, Elizabeth, Martinez, Gabriel, Martinez-Piedra, Ramon, Martini, Santi, Martins-Melo, Francisco Rogerlândio, Martorell, Miquel, Marx, Wolfgang, Maryam, Sharmeen, Mathangasinghe, Yasith, Mathioudakis, Alexander G, Matozinhos, Fernanda Penido, Mattumpuram, Jishanth, Maugeri, Andrea, Maulik, Pallab K, Mayeli, Mahsa, Mazidi, Mohsen, Mazzotti, Antonio, McGrath, John J, McKee, Martin, McKowen, Anna Laura W, McLaughlin, Susan A, McPhail, Michael A, McPhail, Steven M, Mechili, Enkeleint A, Mehmood, Asim, Mehmood, Khalid, Mehrabani-Zeinabad, Kamran, Mehrabi Nasab, Entezar, Meier, Toni, Mejia-Rodriguez, Fabiola, Mekene Meto, Tesfahun, Mekonnen, Birye Dessalegn, Menezes, Ritesh G, Mengist, Belayneh, Mensah, George A, Mensah, Laverne G, Mentis, Alexios-Fotios A, Meo, Sultan Ayoub, Meretoja, Atte, Meretoja, Tuomo J, Mersha, Abera M, Mesfin, Bezawit Afework, Mestrovic, Tomislav, Mettananda, Kukulege Chamila Dinushi, Mettananda, Sachith, Miazgowski, Tomasz, Micha, Georgia, Michalek, Irmina Maria, Micheletti Gomide Nogueira de Sá, Ana Carolina, Miller, Ted R, Mirarefin, Mojde, Mirghafourvand, Mojgan, Mirica, Andreea, Mirijello, Antonio, Mirrakhimov, Erkin M, Mirshahi, Arvin, Mirzaei, Maryam, Mishra, Ajay Kumar, Mishra, Vinaytosh, Mitchell, Philip B, Mithra, Prasanna, Mittal, Chaitanya, Moazen, Babak, Moberg, Madeline E, Mocciaro, Gabriele, Mohamadkhani, Ashraf, Mohamed, Abdalla Z, Mohamed, Ahmed Ismail, Mohamed, Jama, Mohamed, Mouhand F H, Mohamed, Nouh Saad, Mohammadi, Esmaeil, Mohammadi, Saeed, Mohammadian-Hafshejani, Abdollah, Mohammadifard, Noushin, Mohammed, Hussen, Mohammed, Mustapha, Mohammed, Salahuddin, Mohammed, Shafiu, Mokdad, Ali H, Monasta, Lorenzo, Mondello, Stefania, Moni, Mohammad Ali, Moodi Ghalibaf, AmirAli, Moore, Catrin E, Moradi, Maryam, Moradi, Yousef, Moraga, Paula, Morawska, Lidia, Moreira, Rafael Silveira, Morovatdar, Negar, Morrison, Shane Douglas, Morze, Jakub, Mosaddeghi Heris, Reza, Mossialos, Elias, Motappa, Rohith, Mougin, Vincent, Mousavi, Parsa, Msherghi, Ahmed, Mubarik, Sumaira, Muccioli, Lorenzo, Mueller, Ulrich Otto, Mulita, Francesk, Mullany, Erin C, Munjal, Kavita, Murillo-Zamora, Efrén, Murlimanju, BV, Musina, Ana-Maria, Mustafa, Ghulam, Muthu, Sathish, Muthupandian, Saravanan, Muthusamy, Raman, Muzaffar, Muhammad, Myung, Woojae, Nafei, Ayoub, Nagarajan, Ahamarshan Jayaraman, Nagaraju, Shankar Prasad, Nagel, Gabriele, Naghavi, Mohsen, Naghavi, Pirouz, Naik, Ganesh R, Naik, Gurudatta, Nainu, Firzan, Nair, Tapas Sadasivan, Najdaghi, Soroush, Nakhostin Ansari, Noureddin, Nanavaty, Dhairya P, Nangia, Vinay, Narasimha Swamy, Sreenivas, Narimani Davani, Delaram, Nascimento, Bruno Ramos, Nascimento, Gustavo G, Nashwan, Abdulqadir J, Natto, Zuhair S, Nauman, Javaid, Navaratna, Samidi N K, Naveed, Muhammad, Nayak, Biswa Prakash, Nayak, Vinod C, Ndejjo, Rawlance, Nduaguba, Sabina Onyinye, Negash, Hadush, Negoi, Ionut, Negoi, Ruxandra Irina, Nejadghaderi, Seyed Aria, Nejjari, Chakib, Nematollahi, Mohammad Hadi, Nepal, Samata, Neupane, Subas, Ng, Marie, Nguefack-Tsague, Georges, Ngunjiri, Josephine W, Nguyen, Dang H, Nguyen, Nhien Ngoc Y, Nguyen, Phat Tuan, Nguyen, Phuong The, Nguyen, Van Thanh, Nguyen Tran Minh, Duc, Niazi, Robina Khan, Nicholson, Sneha Ingle, Nie, Jing, Nikoobar, Ali, Nikpoor, Amin Reza, Ningrum, Dina Nur Anggraini, Nnaji, Chukwudi A, Noman, Efaq Ali, Nomura, Shuhei, Noroozi, Nafise, Norrving, Bo, Noubiap, Jean Jacques, Nri-Ezedi, Chisom Adaobi, Ntaios, George, Ntsekhe, Mpiko, Nunemo, Mengistu H, Nurrika, Dieta, Nutor, Jerry John, Oancea, Bogdan, O'Connell, Erin M, Odetokun, Ismail A, O'Donnell, Martin James, Oduro, Michael Safo, Ogunfowokan, Adesola Adenike, Ogunkoya, Abiola, Oh, In-Hwan, Okati-Aliabad, Hassan, Okeke, Sylvester Reuben, Okekunle, Akinkunmi Paul, Okonji, Osaretin Christabel, Olagunju, Andrew T, Olasupo, Omotola O, Olatubi, Matthew Idowu, Oliveira, Arão Belitardo, Oliveira, Gláucia Maria Moraes, Olorukooba, Abdulhakeem Abayomi, Olufadewa, Isaac Iyinoluwa, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Oluwafemi, Yinka Doris, Omar, Hany A, Omar Bali, Ahmed, Omer, Goran Latif, Ong, Kanyin Liane, Ong, Sokking, Onwujekwe, Obinna E, Onyedibe, Kenneth Ikenna, Oppong, Anita Frimpomaa, Ordak, Michal, Orish, Verner N, Ornello, Raffaele, Orpana, Heather M, Ortiz, Alberto, Ortiz-Prado, Esteban, Osman, Wael M S, Ostroff, Samuel M, Osuagwu, Uchechukwu Levi, Otoiu, Adrian, Otstavnov, Nikita, Otstavnov, Stanislav S, Ouyahia, Amel, Owolabi, Mayowa O, Oyeyemi, Ifeoluwa Temitayo, Oyeyemi, Oyetunde T, P A, Mahesh Padukudru, Pacheco-Barrios, Kevin, Padron-Monedero, Alicia, Padubidri, Jagadish Rao, Pal, Pramod Kumar, Palicz, Tamás, Pan, Feng, Pan, Hai-Feng, Pana, Adrian, Panda, Sujogya K, Panda-Jonas, Songhomitra, Pandey, Ashok, Pandi-Perumal, Seithikurippu R, Pangaribuan, Helena Ullyartha, Pantazopoulos, Ioannis, Pantea Stoian, Anca Mihaela, Papadopoulou, Paraskevi, Parent, Marie C, Parija, Pragyan Paramita, Parikh, Romil R, Park, Seoyeon, Park, Sungchul, Parsons, Nicholas, Pashaei, Ava, Pasovic, Maja, Passera, Roberto, Patil, Shankargouda, Patoulias, Dimitrios, Patthipati, Venkata Suresh, Paudel, Uttam, Pawar, Shrikant, Pazoki Toroudi, Hamidreza, Peden, Amy E, Pedersini, Paolo, Peng, Minjin, Pensato, Umberto, Pepito, Veincent Christian Filipino, Peprah, Emmanuel K, Peprah, Prince, Peres, Mario F P, Perianayagam, Arokiasamy, Perico, Norberto, Perna, Simone, Pesudovs, Konrad, Petcu, Ionela-Roxana, Petermann-Rocha, Fanny Emily, Pham, Hoang Tran, Philip, Anil K, Phillips, Michael R, Pickering, Brandon V, Pierannunzio, Daniela, Pigeolet, Manon, Pigott, David M, Piracha, Zahra Zahid, Piradov, Michael A, Pisoni, Enrico, Piyasena, Mapa Prabhath, Plass, Dietrich, Plotnikov, Evgenii, Poddighe, Dimitri, Polkinghorne, Kevan R, Poluru, Ramesh, Pond, Constance Dimity, Popovic, Djordje S, Porru, Fabio, Postma, Maarten J, Poudel, Govinda Raj, Pour-Rashidi, Ahmad, Pourshams, Akram, Pourtaheri, Naeimeh, Prabhu, Disha, Prada, Sergio I, Pradhan, Jalandhar, Pradhan, Pranil Man Singh, Prasad, Manya, Prates, Elton Junio Sady, Purnobasuki, Hery, Purohit, Bharathi M, Puvvula, Jagadeesh, Qasim, Nameer Hashim, Qattea, Ibrahim, Qazi, Asma Saleem, Qian, Gangzhen, Qiu, Suli, Rabiee Rad, Mehrdad, Radfar, Amir, Radhakrishnan, Raghu Anekal, Radhakrishnan, Venkatraman, Raeisi Shahraki, Hadi, Rafferty, Quinn, Rafiei, Alireza, Raggi, Alberto, Raghav, Pankaja Raghav, Raheem, Nasiru, Rahim, Fakher, Rahim, Md Jillur, Rahimifard, Mahban, Rahimi-Movaghar, Vafa, Rahman, Md Obaidur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rahmani, Bita, Rahmanian, Mohammad, Rahmanian, Nazanin, Rahmanian, Vahid, Rahmati, Masoud, Rahmawaty, Setyaningrum, Raimondo, Diego, Rajaa, Sathish, Rajendran, Vinoth, Rajput, Prashant, Ramadan, Mahmoud Mohammed, Ramasamy, Shakthi Kumaran, Ramasubramani, Premkumar, Ramazanu, Sheena, Ramteke, Pramod W, Rana, Juwel, Rana, Kritika, Ranabhat, Chhabi Lal, Rane, Amey, Rani, Usha, Ranta, Annemarei, Rao, Chythra R, Rao, Mithun, Rao, Puja C, Rao, Sowmya J, Rasella, Davide, Rashedi, Sina, Rashedi, Vahid, Rashidi, Mahsa, Rashidi, Mohammad-Mahdi, Rasouli-Saravani, Ashkan, Ratan, Zubair Ahmed, Rathnaiah Babu, Giridhara, Rauniyar, Santosh Kumar, Rautalin, Ilari, Rawaf, David Laith, Rawaf, Salman, Rawassizadeh, Reza, Razo, Christian, Reda, Zinabu Ferede Ferede, Reddy, Murali Mohan Rama Krishna, Redwan, Elrashdy Moustafa Mohamed, Reifels, Lennart, Reitsma, Marissa B, Remuzzi, Giuseppe, Reshmi, Bhageerathy, Resnikoff, Serge, Restaino, Stefano, Reyes, Luis Felipe, Rezaei, Maryam, Rezaei, Nazila, Rezaei, Negar, Rezaeian, Mohsen, Rhee, Taeho Gregory, Riaz, Mavra A, Ribeiro, Antonio Luiz P, Rickard, Jennifer, Robinson-Oden, Hannah Elizabeth, Rodrigues, Célia Fortuna, Rodrigues, Mónica, Rodriguez, Jefferson Antonio Buendia, Roever, Leonardo, Romadlon, Debby Syahru, Ronfani, Luca, Rosauer, Jennifer Jacqueline, Roshandel, Gholamreza, Rostamian, Morteza, Rotimi, Kunle, Rout, Himanshu Sekhar, Roy, Bedanta, Roy, Nitai, Rubagotti, Enrico, Ruela, Guilherme de Andrade, Rumisha, Susan Fred, Runghien, Tilleye, Russo, Michele, Ruzzante, Sacha Walde, S N, Chandan, Saad, Aly M A, Saber, Korosh, Saber-Ayad, Maha Mohamed, Sabour, Siamak, Sacco, Simona, Sachdev, Perminder S, Sachdeva, Rajesh, Saddik, Basema, Saddler, Adam, Sadee, Bashdar Abuzed, Sadeghi, Ehsan, Sadeghi, Masoumeh, Sadeghi Majd, Elham, Saeb, Mohammad Reza, Saeed, Umar, Safari, Mehdi, Safi, Sare, Safi, Sher Zaman, Sagar, Rajesh, Sagoe, Dominic, Saheb Sharif-Askari, Fatemeh, Saheb Sharif-Askari, Narjes, Sahebkar, Amirhossein, Sahoo, Soumya Swaroop, Sahu, Monalisha, Saif, Zahra, Sajid, Mirza Rizwan, Sakshaug, Joseph W, Salam, Nasir, Salamati, Payman, Salami, Afeez Abolarinwa, Salaroli, Luciane B, Salehi, Leili, Salehi, Sana, Salem, Marwa Rashad, Salem, Mohammed Z Y, Salihu, Dauda, Salimi, Sohrab, Salum, Giovanni A, Samadi Kafil, Hossein, Samadzadeh, Sara, Samodra, Yoseph Leonardo, Samuel, Vijaya Paul, Samy, Abdallah M, Sanabria, Juan, Sanjeev, Rama Krishna, Sanna, Francesca, Santomauro, Damian Francesco, Santric-Milicevic, Milena M, Sarasmita, Made Ary, Saraswathy, Sivan Yegnanarayana Iyer, Saravanan, Aswini, Saravi, Babak, Sarikhani, Yaser, Sarmiento-Suárez, Rodrigo, Sarode, Gargi Sachin, Sarode, Sachin C, Sartorius, Benn, Sarveazad, Arash, Sathian, Brijesh, Sattin, Davide, Sawhney, Monika, Saya, Ganesh Kumar, Sayeed, Abu, Sayeed, Md Abu, Sayyah, Mehdi, Schinckus, Christophe, Schmidt, Maria Inês, Schuermans, Art, Schumacher, Austin E, Schutte, Aletta Elisabeth, Schwarzinger, Michaël, Schwebel, David C, Schwendicke, Falk, Selvaraj, Siddharthan, Semreen, Mohammad H, Senthilkumaran, Subramanian, Serban, Dragos, Serre, Marc L, Sethi, Yashendra, Shafie, Mahan, Shah, Humaira, Shah, Nilay S, Shah, Pritik A, Shah, Syed Mahboob, Shahbandi, Ataollah, Shaheen, Amira A, Shahid, Samiah, Shahid, Wajeehah, Shahsavari, Hamid R, Shahwan, Moyad Jamal, Shaikh, Masood Ali, Shaikh, Summaiya Zareen, Shalash, Ali S, Sham, Sunder, Shamim, Muhammad Aaqib, Shams-Beyranvand, Mehran, Shamshirgaran, Mohammad Ali, Shamsi, Mohammad Anas, Shanawaz, Mohd, Shankar, Abhishek, Sharfaei, Sadaf, Sharifan, Amin, Sharifi-Rad, Javad, Sharma, Manoj, Sharma, Ujjawal, Sharma, Vishal, Shastry, Rajesh P, Shavandi, Amin, Shehabeldine, Amr Mohamed Elsayed, Shehzadi, Somia, Sheikh, Aziz, Shen, Jiabin, Shetty, Adithi, Shetty, B Suresh Kumar, Shetty, Pavanchand H, Shiani, Amir, Shiferaw, Desalegn, Shigematsu, Mika, Shin, Min-Jeong, Shiri, Rahman, Shittu, Aminu, Shiue, Ivy, Shivakumar, K M, Shivarov, Velizar, Shool, Sina, Shorofi, Seyed Afshin, Shrestha, Rajan, Shrestha, Sunil, Shuja, Kanwar Hamza, Shuval, Kerem, Si, Yafei, Siddig, Emmanuel Edwar, Silva, Diego Augusto Santos, Silva, Luís Manuel Lopes Rodrigues, Silva, Soraia, Silva, Thales Philipe R, Simpson, Colin R, Singh, Abhinav, Singh, Balbir Bagicha, Singh, Baljinder, Singh, Garima, Singh, Harmanjit, Singh, Jasvinder A, Singh, Mahendra, Singh, Narinder Pal, Singh, Paramdeep, Singh, Surjit, Sinto, Robert, Sivakumar, Shravan, Siwal, Samarjeet Singh, Skhvitaridze, Natia, Skou, Søren T, Sleet, David A, Sobia, Farrukh, Soboka, Matiwos, Socea, Bogdan, Solaimanian, Shahabaddin, Solanki, Ranjan, Solanki, Shipra, Soliman, Sameh S M, Somayaji, Ranjani, Song, Yi, Sorensen, Reed J D, Soriano, Joan B, Soyiri, Ireneous N, Spartalis, Michael, Spearman, Sandra, Spencer, Cory N, Sreeramareddy, Chandrashekhar T, Stachteas, Panagiotis, Stafford, Lauryn K, Stanaway, Jeffrey D, Stanikzai, Muhammad Haroon, Stein, Caroline, Stein, Dan J, Steinbeis, Fridolin, Steiner, Caitlyn, Steinke, Sabine, Steiropoulos, Paschalis, Stockfelt, Leo, Stokes, Mark A, Straif, Kurt, Stranges, Saverio, Subedi, Narayan, Subramaniyan, Vetriselvan, Suleman, Muhammad, Suliankatchi Abdulkader, Rizwan, Sundström, Johan, Sunkersing, David, Sunnerhagen, Katharina S, Suresh, Vinay, Swain, Chandan Kumar, Szarpak, Lukasz, Szeto, Mindy D, Tabaee Damavandi, Payam, Tabarés-Seisdedos, Rafael, Tabatabaei, Seyyed Mohammad, Tabatabaei Malazy, Ozra, Tabatabaeizadeh, Seyed-Amir, Tabatabai, Shima, Tabche, Celine, Tabish, Mohammad, Tadakamadla, Santosh Kumar, Taheri Abkenar, Yasaman, Taheri Soodejani, Moslem, Taherkhani, Amir, Taiba, Jabeen, Takahashi, Ken, Talaat, Iman M, Tamuzi, Jacques Lukenze, Tan, Ker-Kan, Tang, Haosu, Tat, Nathan Y, Taveira, Nuno, Tefera, Yibekal Manaye, Tehrani-Banihashemi, Arash, Temesgen, Worku Animaw, Temsah, Mohamad-Hani, Teramoto, Masayuki, Terefa, Dufera Rikitu, Teye-Kwadjo, Enoch, Thakur, Ramna, Thangaraju, Pugazhenthan, Thankappan, Kavumpurathu Raman, Thapar, Rekha, Thayakaran, Rasiah, Thirunavukkarasu, Sathish, Thomas, Nihal, Thomas, Nikhil Kenny, Tian, Jing, Tichopad, Ales, Ticoalu, Jansje Henny Vera, Tiruye, Tenaw Yimer, Tobe-Gai, Ruoyan, Tolani, Musliu Adetola, Tolossa, Tadesse, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Fotis, Touvier, Mathilde, Tovani-Palone, Marcos Roberto, Trabelsi, Khaled, Tran, Jasmine T, Tran, Mai Thi Ngoc, Tran, Nghia Minh, Trico, Domenico, Trihandini, Indang, Troeger, Christopher E, Tromans, Samuel Joseph, Truyen, Thien Tan Tri Tai, Tsatsakis, Aristidis, Tsermpini, Evangelia Eirini, Tumurkhuu, Munkhtuya, Udoakang, Aniefiok John, Udoh, Arit, Ullah, Atta, Ullah, Saeed, Ullah, Sana, Umair, Muhammad, Umakanthan, Srikanth, Unim, Brigid, Unnikrishnan, Bhaskaran, Upadhyay, Era, Urso, Daniele, Usman, Jibrin Sammani, Vaithinathan, Asokan Govindaraj, Vakili, Omid, Valenti, Mario, Valizadeh, Rohollah, Van den Eynde, Jef, van Donkelaar, Aaron, Varga, Orsolya, Vart, Priya, Varthya, Shoban Babu, Vasankari, Tommi Juhani, Vasic, Milena, Vaziri, Siavash, Venketasubramanian, Narayanaswamy, Verghese, Nicholas Alexander, Verma, Madhur, Veroux, Massimiliano, Verras, Georgios-Ioannis, Vervoort, Dominique, Villafañe, Jorge Hugo, Villalobos-Daniel, Victor E, Villani, Leonardo, Villanueva, Gabriela Ines, Vinayak, Manish, Violante, Francesco S, Vlassov, Vasily, Vo, Bay, Vollset, Stein Emil, Volovat, Simona Ruxandra, Vos, Theo, Vujcic, Isidora S, Waheed, Yasir, Wang, Cong, Wang, Fang, Wang, Shu, Wang, Yanzhong, Wang, Yuan-Pang, Wanjau, Mary Njeri, Waqas, Muhammad, Ward, Paul, Waris, Abdul, Wassie, Emebet Gashaw, Weerakoon, Kosala Gayan, Weintraub, Robert G, Weiss, Daniel J, Weiss, Eli J, Weldetinsaa, Haftom Legese Legese, Wells, Katherine M, Wen, Yi Feng, Wiangkham, Taweewat, Wickramasinghe, Nuwan Darshana, Wilkerson, Caroline, Willeit, Peter, Wilson, Shadrach, Wong, Yen Jun, Wongsin, Utoomporn, Wozniak, Sarah, Wu, Chenkai, Wu, Dongze, Wu, Felicia, Wu, Zenghong, Xia, Juan, Xiao, Hong, Xu, Suowen, Xu, Xiaoyue, Xu, Yvonne Yiru, Yadav, Mukesh Kumar, Yaghoubi, Sajad, Yamagishi, Kazumasa, Yang, Lin, Yano, Yuichiro, Yaribeygi, Habib, Yasufuku, Yuichi, Ye, Pengpeng, Yesodharan, Renjulal, Yesuf, Subah Abderehim, Yezli, Saber, Yi, Siyan, Yiğit, Arzu, Yigzaw, Zeamanuel Anteneh, Yin, Dehui, Yip, Paul, Yismaw, Malede Berihun, Yon, Dong Keon, Yonemoto, Naohiro, You, Yuyi, Younis, Mustafa Z, Yousefi, Zabihollah, Yu, Chuanhua, Yu, Yong, Zadey, Siddhesh, Zadnik, Vesna, Zakham, Fathiah, Zaki, Nazar, Zakzuk, Josefina, Zamagni, Giulia, Zaman, Sojib Bin, Zandieh, Ghazal G Z, Zanghì, Aurora, Zar, Heather J, Zare, Iman, Zarimeidani, Fatemeh, Zastrozhin, Mikhail Sergeevich, Zeng, Youjie, Zhai, Chunxia, Zhang, Anthony Lin, Zhang, Haijun, Zhang, Liqun, Zhang, Meixin, Zhang, Yunquan, Zhang, Zhenyu, Zhang, Zhi-Jiang, Zhao, Hanqing, Zhao, Jeff T, Zhao, Xiu-Ju George, Zhao, Yang, Zhao, Yong, Zhong, Chenwen, Zhou, Jingjing, Zhou, Juexiao, Zhou, Shangcheng, Zhu, Bin, Zhu, Lei, Zhu, Zhaohua, Ziaeian, Boback, Ziafati, Makan, Zielińska, Magdalena, Zimsen, Stephanie R M, Zoghi, Ghazal, Zoller, Thomas, Zumla, Alimuddin, Zyoud, Sa'ed H, Zyoud, Samer H, Murray, Christopher J L, and Gakidou, Emmanuela
- Published
- 2024
5. Cortical plasticity in phantom limb pain: A fMRI study on the neural correlates of behavioral clinical manifestations.
- Author
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Duarte, D., Bauer, C.C.C., Pinto, C.B., Saleh Velez, F.G., Estudillo-Guerra, M.A., Pacheco-Barrios, K., Gunduz, M.E., Crandell, D., Merabet, L., and Fregni, F.
- Published
- 2020
- Full Text
- View/download PDF
6. Structural and functional motor cortex asymmetry in unilateral lower limb amputation with phantom limb pain
- Author
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Pacheco-Barrios, K., Pinto, CB., Saleh Velez, FG., Duarte, D., Gunduz, ME., Simis, M., Lepesteur Gianlorenco, AC., Barouh, JL., Crandell, D., Guidetti, M., Battistella, L., and Fregni, F.
- Published
- 2020
- Full Text
- View/download PDF
7. The pros and cons of tDCS as a therapeutic tool in the rehabilitation of chronic pain
- Author
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Ho, JS., Slawka, E., Pacheco-Barrios, K., Cardenas-Rojas, A., Castelo-Branco, L., and Fregni, F.
- Subjects
General Earth and Planetary Sciences ,Article ,General Environmental Science - Published
- 2022
8. Detangling the structural neural correlates associated with resting versus dynamic phantom limb pain intensity using a voxel-based morphometry analysis
- Author
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Pinto, C B, primary, Pacheco-Barrios, K, additional, Saleh Velez, F G, additional, Gunduz, M E, additional, Münger, M, additional, and Fregni, F, additional
- Published
- 2022
- Full Text
- View/download PDF
9. Digitalized transcranial electrical stimulation: A consensus statement
- Author
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Brunoni, A. R., Ekhtiari, H., Antal, A., Auvichayapat, P., Baeken, C., Bensenor, I. M., Bikson, M., Boggio, P., Borroni, B., Brighina, F., Brunelin, J., Carvalho, S., Caumo, W., Ciechanski, P., Charvet, L., Clark, V. P., Cohen Kadosh, R., Cotelli, Maria, Datta, A., Deng, Z. -D., De Raedt, R., De Ridder, D., Fitzgerald, P. B., Floel, A., Frohlich, F., George, M. S., Ghobadi-Azbari, P., Goerigk, S., Hamilton, R. H., Jaberzadeh, S. J., Hoy, K., Kidgell, D. J., Zonoozi, A. K., Kirton, A., Laureys, S., Lavidor, M., Lee, K., Leite, J., Lisanby, S. H., Loo, C., Martin, D. M., Miniussi, C., Mondino, M., Monte-Silva, K., Morales-Quezada, L., Nitsche, M. A., Okano, A. H., Oliveira, C. S., Onarheim, B., Pacheco-Barrios, K., Padberg, F., Nakamura-Palacios, E. M., Palm, U., Paulus, W., Plewnia, C., Priori, A., Rajji, T. K., Razza, L. B., Rehn, E. M., Ruffini, G., Schellhorn, K., Zare-Bidoky, M., Simis, M., Skorupinski, P., Suen, P., Thibaut, A., Valiengo, L. C. L., Vanderhasselt, M. -A., Vanneste, S., Venkatasubramanian, G., Violante, I. R., Wexler, A., Woods, A. J., Fregni, F., Cotelli M., Brunoni, A. R., Ekhtiari, H., Antal, A., Auvichayapat, P., Baeken, C., Bensenor, I. M., Bikson, M., Boggio, P., Borroni, B., Brighina, F., Brunelin, J., Carvalho, S., Caumo, W., Ciechanski, P., Charvet, L., Clark, V. P., Cohen Kadosh, R., Cotelli, Maria, Datta, A., Deng, Z. -D., De Raedt, R., De Ridder, D., Fitzgerald, P. B., Floel, A., Frohlich, F., George, M. S., Ghobadi-Azbari, P., Goerigk, S., Hamilton, R. H., Jaberzadeh, S. J., Hoy, K., Kidgell, D. J., Zonoozi, A. K., Kirton, A., Laureys, S., Lavidor, M., Lee, K., Leite, J., Lisanby, S. H., Loo, C., Martin, D. M., Miniussi, C., Mondino, M., Monte-Silva, K., Morales-Quezada, L., Nitsche, M. A., Okano, A. H., Oliveira, C. S., Onarheim, B., Pacheco-Barrios, K., Padberg, F., Nakamura-Palacios, E. M., Palm, U., Paulus, W., Plewnia, C., Priori, A., Rajji, T. K., Razza, L. B., Rehn, E. M., Ruffini, G., Schellhorn, K., Zare-Bidoky, M., Simis, M., Skorupinski, P., Suen, P., Thibaut, A., Valiengo, L. C. L., Vanderhasselt, M. -A., Vanneste, S., Venkatasubramanian, G., Violante, I. R., Wexler, A., Woods, A. J., Fregni, F., and Cotelli M.
- Abstract
Objective: Although relatively costly and non-scalable, non-invasive neuromodulation interventions are treatment alternatives for neuropsychiatric disorders. The recent developments of highly-deployable transcranial electric stimulation (tES) systems, combined with mobile-Health technologies, could be incorporated in digital trials to overcome methodological barriers and increase equity of access. The study aims are to discuss the implementation of tES digital trials by performing a systematic scoping review and strategic process mapping, evaluate methodological aspects of tES digital trial designs, and provide Delphi-based recommendations for implementing digital trials using tES. Methods: We convened 61 highly-productive specialists and contacted 8 tES companies to assess 71 issues related to tES digitalization readiness, and processes, barriers, advantages, and opportunities for implementing tES digital trials. Delphi-based recommendations (>60% agreement) were provided. Results: The main strengths/opportunities of tES were: (i) non-pharmacological nature (92% of agreement), safety of these techniques (80%), affordability (88%), and potential scalability (78%). As for weaknesses/threats, we listed insufficient supervision (76%) and unclear regulatory status (69%). Many issues related to methodological biases did not reach consensus. Device appraisal showed moderate digitalization readiness, with high safety and potential for trial implementation, but low connectivity. Conclusions: Panelists recognized the potential of tES for scalability, generalizability, and leverage of digital trials processes; with no consensus about aspects regarding methodological biases. Significance: We further propose and discuss a conceptual framework for exploiting shared aspects between mobile-Health tES technologies with digital trials methodology to drive future efforts for digitizing tES trials.
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- 2022
10. More work needed on decision analysis for shared decision-making: A scoping review
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Humphries, B, Leon-Garcia, M, Quispe, END, Canelo-Aybar, C, Valli, C, Pacheco-Barrios, K, Agarwal, A, Mirabi, S, Eckman, MH, Guyatt, G, Bates, SM, Alonso-Coello, P, and Xie, F
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decision analysis ,clinical decision-making ,review article ,scoping review ,patient preferences ,Shared decision-making - Abstract
Objective: To explore and characterize published evidence on the ways decision analysis has been used to inform shared decision making. Study Design and Setting: For this scoping review, we searched five bibliographic databases (from inception until February 2021), reference lists of included studies, trial registries, a thesis database and websites of relevant interest groups. Studies were eligible if they evaluated the application of decision analysis in a shared decision-making encounter. Pairs of reviewers independently screened and selected studies for inclusion, extracted study information using a data extraction form developed by the research team and assessed risk of bias for all studies with an experimental or quasi-experimental design. Data were narratively synthesized. Results: We identified 27 studies that varied greatly with regard to their patient population, design, content and delivery. A range of outcomes were evaluated to explore the effectiveness and acceptability of decision analytic interventions, with little information about the implementation process. Most studies found that decision analysis was broadly beneficial. Conclusion: Despite the compelling rationale on the potential for decision analysis to support shared decision-making, rigorous randomized controlled trials are needed to confirm these interventions' effectiveness, while qualitative studies should seek to understand their potential implementation. (c) 2021 Elsevier Inc. All rights reserved.
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- 2022
11. Methods to Summarize Discrete-Choice Experiments in a Systematic Review: A Scoping Review
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Choudhary, D, Thomas, M, Pacheco-Barrios, K, Zhang, Y, Alonso-Coello, P, Schunemann, H, and Hazlewood, G
- Abstract
Background and Objective Systematic reviews of discrete-choice experiments (DCEs) are being increasingly conducted. The objective of this scoping review was to identify and describe the methodologies that have been used to summarize results across DCEs. Methods We searched the electronic databases MEDLINE and EMBASE from inception to March 18, 2021, to identify English-language systematic reviews of patient preferences that included at least two DCEs and extracted data on attribute importance. The methods used to summarize results across DCEs were classified into narrative, semi-quantitative, and quantitative (meta-analytic) approaches and compared. Approaches to characterize the extent of preference heterogeneity were also described. Results From 7362 unique records, we identified 54 eligible reviews from 2010 to Mar 2021, across a broad range of health conditions. Most (83%) used a narrative approach to summarize findings of DCEs, often citing differences in studies as the reason for not formally pooling findings. Semi-quantitative approaches included summarizing the frequency of the most important attributes, the frequency of attribute statistical significance, or tabulated comparisons of attribute importance for each pair of attributes. One review conducted a meta-analysis using the maximum acceptable risk. While reviews often commented on the heterogeneity of patient preferences, few (6%) addressed this systematically across studies. Conclusion While not commonly used, several semi-quantitative and one quantitative approach for synthesizing results of DCEs were identified, which may be useful for generating summary estimates across DCEs when appropriate. Further work is needed to assess the validity and usefulness of these approaches.
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- 2022
12. Inflammatory cytokines during a manic episode in bd patients and its correlation with cognitive and affective symptoms at follow-up
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Guerra, M. Estudillo, primary, Suarez, G. Torres, additional, Mesia-Toledo, I., additional, Pacheco-Barrios, K., additional, and Ramírez-Bemúdez, J., additional
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- 2021
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13. C9orf72 Hexanucleotide Repeat in Huntington-Like Patients: Systematic Review and Meta-Analysis
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Alva-Diaz, C., Alarcon-Ruiz, C.A., Pacheco-Barrios, K., Mori, N., Pacheco-Mendoza, J., Traynor, B.J., Rivera-Valdivia, A., Lertwilaiwittaya, P., Bird, T.D., and Cornejo-Olivas, M.
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prevalence studies ,systematic review ,C9orf72 ,chorea ,Huntington like disorders ,purl.org/pe-repo/ocde/ford#1.06.07 [https] - Abstract
Introduction: Patients with Huntington-Like disorders (HLD) comprise a variety of allelic disorders sharing a Huntington phenotype. The hexanucleotide repeat expansion of the C9orf72 gene could explain part of the HLD etiology. We aimed to conduct a systematic review and meta-analysis looking for the frequency of the hexanucleotide repeat expansion of the C9orf72 gene in HLD patients. Methods: The protocol was registered on the International Prospective Register of Systematic Reviews database (PROSPERO) (registration number: CRD42018105465). The search was carried out in Medline, Scopus, Web of Science, and Embase in April 2018, and updated in July 2020. Observational studies reporting patients with HLD carrying the hexanucleotide repeat expansion in the C9orf72 gene were selected and reviewed; this process was duplicated. The cutoff threshold for considering the hexanucleotide expansion as a pathogenic variant was equal to or >30 G4C2 repeats. Cases with intermediate alleles with 20–29 repeat are also analyzed. Pooled frequency and 95% CI were calculated using random-effects models. Results: Nine out of 219 studies were selected, reporting 1,123 affected individuals with HLD. Among them, 18 individuals carried C9orf72 expansion, representing 1% (95% CI: 0–2%, I2 = 0%) of the pooled frequency. Seven selected studies came from European centers, one was reported at a US center, and one came from a South-African center. We identified five individuals carrying intermediate alleles representing 3% (95% CI: 0–14%, I2 = 78.5%). Conclusions: The frequency of C9orf72 unstable hexanucleotide repeat expansion in HLD patients is very low. Further studies with more accurate clinical data and from different ethnic backgrounds are needed to confirm this observation.
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- 2020
14. Burden of disease due to stroke in Latin America: A systematic analysis of the global burden disease study 2017
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Pacheco-Barrios, K., primary, Giannoni-Luza, S., additional, and Alva-Diaz, C., additional
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- 2019
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15. Burden of disease due to epilepsy in Latin America: A systematic analysis of the global burden disease study 2017
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Pacheco-Barrios, K., primary, Cardenas-Rojas, A., additional, and Alva-Diaz, C., additional
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- 2019
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16. Inflammatory cytokines during a manic episode in bd patients and its correlation with cognitive and affective symptoms at follow-up.
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Estudillo Guerra, M., Torres Suarez, G., Mesia-Toledo, I., Pacheco-Barrios, K., and Ramírez-Bemúdez, J.
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CYTOKINES ,AFFECT (Psychology) ,COGNITIVE ability ,IMMUNE system ,BIPOLAR disorder - Abstract
Introduction: Bipolar Disorder (BD) is a severe recurrent disorder with a complex biogenetic and psychosocial etiology. The immune system cytokines in interaction with the CNS play a role in the pathophysiology. Objectives: To compare inflammatory cytokines between BD patients and controls during the manic episode; additionally, compare these cytokines with psychiatric symptoms and cognitive performance during follow-up. Methods: We recruited 25 BD patients in mania with paired controls. We measured baseline IL-2, IL-4, IL-8, IL-10, GM-CSG, TNF-α, and TNF-γ in plasma. We used U-Mann-Whitney for group comparison and Spearman correlation between sub-group follow-up assessments and cytokines. Results: We found a significant difference in IL-6 between subjects and controls (figure 1). During the follow-up, we found a correlation with psychiatric symptoms, cognition, and cytokines during manic episodes (Table 1). Table 1. Follow-up Correlation with cytokines during a manic episode. (+): positive correlation; (-): negative correlation. WMT: workingmemory test, PST: Processing-speed test. Conclusions: IL-6 was significantly different in patients with BD during a manic episode regardless of the treatment they were taking. IL-10 at manic episode was negatively correlated to general psychiatric symptoms, IL-4 positive correlated to depressive symptoms, and cognitive performance was positively correlated to TNF-α and TNF-γ at follow-up. [ABSTRACT FROM AUTHOR]
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- 2021
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17. Evidence-based guidelines and secondary meta-analysis for the use of transcranial direct current stimulation in neurological and psychiatric disorders
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Wolnei Caumo, Paola Marangolo, Jerome Brunelin, Ester Miyuki Nakamura-Palacios, Marcel Simis, Marom Bikson, Felipe Fregni, Mirret M. El-Hagrassy, Sandra Carvalho, Daniel San-Juan, Ganesan Venkatasubramanian, Jorge Leite, Andre R. Brunoni, Kevin Pacheco-Barrios, Fregni, F, El-Hagrassy, Mm, Pacheco-Barrios, K, Carvalho, S, Leite, J, Simis, M, Brunelin, J, Nakamura-Palacios, Em, Marangolo, P, Venkatasubramanian, G, San-Juan, D, Caumo, W, Bikson, M, and Brunoni, Ar.
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medicine.medical_specialty ,Evidence-based medicine ,AcademicSubjects/MED00415 ,medicine.medical_treatment ,neurological disorders ,Pain ,Review ,Transcranial Direct Current Stimulation ,Tourette syndrome ,tDCS ,03 medical and health sciences ,0302 clinical medicine ,Physical medicine and rehabilitation ,Fibromyalgia ,Clinical evidence ,medicine ,Humans ,Pharmacology (medical) ,Pharmacology ,Brain Diseases ,Evidence-Based Medicine ,Transcranial direct-current stimulation ,AcademicSubjects/SCI01870 ,business.industry ,Mental Disorders ,Clinical study design ,medicine.disease ,3. Good health ,030227 psychiatry ,Clinical trial ,clinical evidence ,Psychiatry and Mental health ,psychiatric disorders ,Schizophrenia ,Meta-analysis ,Practice Guidelines as Topic ,Major depressive disorder ,business ,Psychiatric disorders ,030217 neurology & neurosurgery ,Neurological disorders - Abstract
Background Transcranial direct current stimulation has shown promising clinical results, leading to increased demand for an evidence-based review on its clinical effects. Objective We convened a team of transcranial direct current stimulation experts to conduct a systematic review of clinical trials with more than 1 session of stimulation testing: pain, Parkinson’s disease motor function and cognition, stroke motor function and language, epilepsy, major depressive disorder, obsessive compulsive disorder, Tourette syndrome, schizophrenia, and drug addiction. Methods Experts were asked to conduct this systematic review according to the search methodology from PRISMA guidelines. Recommendations on efficacy were categorized into Levels A (definitely effective), B (probably effective), C (possibly effective), or no recommendation. We assessed risk of bias for all included studies to confirm whether results were driven by potentially biased studies. Results Although most of the clinical trials have been designed as proof-of-concept trials, some of the indications analyzed in this review can be considered as definitely effective (Level A), such as depression, and probably effective (Level B), such as neuropathic pain, fibromyalgia, migraine, post-operative patient-controlled analgesia and pain, Parkinson’s disease (motor and cognition), stroke (motor), epilepsy, schizophrenia, and alcohol addiction. Assessment of bias showed that most of the studies had low risk of biases, and sensitivity analysis for bias did not change these results. Effect sizes vary from 0.01 to 0.70 and were significant in about 8 conditions, with the largest effect size being in postoperative acute pain and smaller in stroke motor recovery (nonsignificant when combined with robotic therapy). Conclusion All recommendations listed here are based on current published PubMed-indexed data. Despite high levels of evidence in some conditions, it must be underscored that effect sizes and duration of effects are often limited; thus, real clinical impact needs to be further determined with different study designs.
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- 2020
18. High Body Mass Index Disrupts the Homeostatic Effects of Pain Inhibitory Control in the Symptomatology of Patients With Fibromyalgia.
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Lacerda GJM, Pacheco-Barrios K, and Fregni F
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This study examines the influence of body mass index (BMI) on the relationship between quantitative sensory testing measures and clinical characteristics in fibromyalgia syndrome (FMS). Utilizing BMI as a categorical covariate (≥25 or ≥30 kg/m²) in associations between quantitative sensory testing metrics (pain-60, conditioned pain modulation, and temporal summation of pain [TSP]) and FMS clinical features, we explored BMI's role as both a confounder (change-in-estimate criterion-change equal or higher than 10%) and effect modifier (interaction term). Significant interactions revealed overweight/obese BMI as a modifier in the relationship between conditioned pain modification and both depression and symptom impact, with a homeostatic relationship between better clinical profile and pain inhibitory response observed solely in the normal-weight group. Similar results were found for pain-60 and depression. Additionally, BMI ≥30 kg/m² modified TSP's effect on pain, demonstrating lower pain with increased TSP, exclusively in the nonobese group. This study highlights the significant role of BMI in moderating the relationships of important pain inhibitory control processes and pain intensity, depression, and the overall impact of FMS symptoms. Our results suggest that high BMI states disrupt the homeostatic effects of pain inhibition, reducing its salutogenic response in FMS participants. We discuss the mechanistic and therapeutic implications of targeting BMI in FMS clinical trials and the potential impact of this important relationship. PERSPECTIVE: This investigation highlights the disruptive influence of high BMI on pain inhibitory control in fibromyalgia, unbalancing clinical symptoms such as pain and depression. It underscores the necessity of integrating BMI considerations into therapeutic approaches to enhance pain management and patient outcomes., (Copyright © 2024 United States Association for the Study of Pain, Inc. Published by Elsevier Inc. All rights reserved.)
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- 2024
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19. Disruptive compensatory mechanisms in fibromyalgia syndrome and their association with pharmacological agents.
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Silva FMQ, Pacheco-Barrios K, and Fregni F
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Fibromyalgia syndrome (FMS) is a chronic disorder characterized commonly by widespread musculoskeletal pain and fatigue, predominantly affecting women, with its complexity often leading to underdiagnosis and complicating treatment effectiveness. Transcranial magnetic stimulation (TMS) metrics are potential markers to optimize FMS treatments; however, evidence is limited. Our study aimed to explore the relationship between cortical excitability and inhibition, assessed through TMS markers, and clinical characteristics in patients with FMS. This presented cross-sectional study employed baseline data from a clinical trial with 108 FMS patients, mostly female (88.8%), and mean age of 47.3 years old (SD = 12.06). Our analysis showed that decreased short-intracortical inhibition (SICI) was associated with gabapentinoids use, nicotine history, and increased fatigue levels, suggesting its connection with compensatory mechanisms for non-painful FMS features. Increased motor intracortical facilitation (ICF) was linked with greater pain severity and shorter FMS duration, implying its relationship with a reorganization of sensorimotor pathways due to chronic pain. Additionally, higher resting motor threshold (rMT) was associated with less effective pain modulation (lower conditioned pain modulation [CPM]), indicating a disruption of pain compensatory mechanism. Given the role of SICI in indexing homeostatic brain mechanisms and its association with fatigue, a hallmark characteristic of FMS-induced behavioral changes, these results suggest that FMS likely has a deleterious effect on brain inhibitory function, thus providing a potential novel insight for FMS mechanisms. In addition, it seems that this compensatory mechanism's disruption is enhanced by pharmacological agents such as gabapentioids and nicotine., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2024
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20. Effect of Neurostimulation on Chronic Pancreatic Pain: A Systematic Review.
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Andrade MF, Fabris-Moraes W, Pacheco-Barrios K, and Fregni F
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Background: Chronic pancreatic pain is one of the most severe causes of visceral pain, and treatment response is often limited. Neurostimulation techniques have been investigated for chronic pain syndromes once there are pathophysiological reasons to believe that these methods activate descending pain inhibitory systems. Considering this, we designed this systematic literature review to investigate the evidence on neuromodulation techniques as a treatment for chronic pancreatic pain., Materials and Methods: We performed a literature search using the databases MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), and Embase until April 2024. The included studies used neurostimulation techniques in participants with chronic pancreatic pain and reported pain-related outcomes, with a focus on pain scales and opioid intake. Two reviewers screened and extracted data, and a third reviewer resolved discrepancies. We assessed the risk of bias using the Jadad scale. The authors then grouped the findings by the target of the neurostimulation, cortex, spinal cord, or peripheral nerves; described the findings qualitatively in the results section, including qualitative data reported by the articles; and calculated effect sizes of pain-related outcomes., Results: A total of 22 studies were included (7 randomized clinical trials [RCTs], 14 case series, and 1 survey), including a total of 257 clinical trial participants. The two outcomes most commonly reported were pain, measured by the visual analogue scale (VAS), numeric rating scale (NRS), and pressure pain threshold scores, and opioid intake. Two RCTs investigated repetitive transcranial magnetic stimulation (rTMS), showing a reduction of 36% (±16) (d = 2.25; 95% CI, 0.66-3.83) and 27.2% (±24.5%) (d = 2.594; 95% CI, 1.303-3.885) in VAS pain scale. In another clinical trial, transcranial direct-current stimulation (tDCS) and transcranial pulsed current stimulation were not observed to effect a significant reduction in VAS pain (χ2 = 5.87; p = 0.12). However, a complete remission was reported in one tDCS case. Spinal cord stimulation (SCS) and dorsal root ganglion stimulation were performed in a survey and 11 case series, showing major pain decrease and diminished opioid use in 90% of participants after successful implantation; most studies had follow-up periods of months to years. Two noninvasive vagal nerve stimulation (VNS) RCTs showed no significant pain reduction in pain thresholds or VAS (d = 0.916; 95% CI, -0.005 to 1.838; and d = 0.17; -0.86 to 1.20; p = 0.72; respectively). Splanchnic nerve stimulation in one case report showed complete pain reduction accompanied by discontinuation of oral morphine and fentanyl lozenges and a 95% decrease in fentanyl patch use. Two RCTs investigated transcutaneous electrical nerve stimulation (TENS). One found a significant pain reduction effect with the NRS (d = 1.481; 95% CI, 1.82-1.143), and decreased opioid use, while the other RCT did not show significant benefit. Additionally, one case report with TENS showed pain improvement that was not quantitatively measured., Discussion: The neuromodulation techniques of rTMS and SCS showed the most consistent potential as a treatment method for chronic pancreatic pain. However, the studies have notable limitations, and SCS has had no clinical trials. For VNS, we have two RCTs that showed a non-statistically significant improvement; we believe that both studies had a lack of power issue and suggest a gap in the literature for new RCTs exploring this modality. Additionally, tDCS and TENS showed mixed results. Another important insight was that opioid intake decrease is a common trend among most studies included and that adverse effects were rarely reported. To further elucidate the potential of these neurostimulation techniques, we suggest the development of new clinical trials with larger samples and adequate sham controls., Competing Interests: Conflict of Interest The authors reported no conflict of interest., (Copyright © 2024 International Neuromodulation Society. Published by Elsevier Inc. All rights reserved.)
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- 2024
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21. The Link between Endogenous Pain Modulation Changes and Clinical Improvement in Fibromyalgia Syndrome: A Meta-Regression Analysis.
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Pacheco-Barrios K, Filardi RM, González-González LF, Park N, Petrus FQ, Navarro-Flores A, Di-Bonaventura S, Alves LG, Queiroz F, and Fregni F
- Abstract
Conditioned pain modulation (CPM) and temporal summation (TS) tests can measure the ability to inhibit pain in fibromyalgia syndrome (FMS) patients and its level of pain sensitization, respectively. However, their clinical validity is still unclear. We studied the association between changes in the CPM and TS tests and the clinical improvement of FMS patients who received therapeutic intervention. We systematically searched for FMS randomized clinical trials with data on therapeutic interventions comparing clinical improvement (pain intensity and symptom severity reduction), CPM, and TS changes relative to control interventions. To study the relationship between TS/CPM and clinical measures, we performed a meta-regression analysis to calculate odds ratios. We included nine studies (484 participants). We found no significant changes in TS or CPM by studying all the interventions together. Our findings show that this lack of difference is likely because pharmacological and non-pharmacological interventions resulted in contrary effects. Non-pharmacological interventions, such as non-invasive neuromodulation, showed the largest effects normalizing CPM/TS. Meta-regression was significantly associated with pain reduction and symptom severity improvement with normalization of TS and CPM. We demonstrate an association between clinical improvement and TS/CPM normalization in FMS patients. Thus, the TS and CPM tests could be surrogate biomarkers in FMS management. Recovering defective endogenous pain modulation mechanisms by targeted non-pharmacological interventions may help establish long-term clinical recovery in FMS patients.
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- 2024
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22. Neural correlates of phantom motor execution: A functional neuroimaging systematic review and meta-analysis.
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Pacheco-Barrios K, Heemels RE, Martinez-Magallanes D, Daibes M, Naqui-Xicota C, Andrade M, and Fregni F
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Phantom motor execution (PME) shows promise as a new treatment for phantom limb pain (PLP) by inducing motor-related analgesia and retraining the pain network activation. However, the current understanding of the neural correlates underlying PME is limited. Databases were systematically searched for multimodal neuroimaging studies to explore the neural correlates of PME. A narrative synthesis (17 studies, n = 328) and coordinate-based meta-analysis were performed to identify activation commonalities. Contrasting PME-vs-REST revealed differential activation of the supplementary motor area (SMA), post-central gyrus, and dorsolateral superior frontal gyrus; while PME-vs-ME revealed differential activation of the right anterior insula, anterior cingulate, left amygdala, and right striatum. Further narrative synthesis revealed a positive correlation between PME-induced brain activity and PLP intensity, and a specific connectivity pattern during PME on the SMA-M1 network compared to ME and motor imagery. Our results suggest that the PME represents a distinct type of motor network activation, partially overlapping with ME and motor imagery activations but with special activation of interoceptive regulation and mood-related regions. Thus, confirming its potential as a therapeutic approach for PLP., (Copyright © 2024 Elsevier Ltd. All rights reserved.)
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- 2024
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23. Clinical Characteristics Associated with the PLP-PLS Index, a New Potential Metric to Phenotype Phantom Limb Pain.
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Ortega-Márquez J, Garnier J, Mena L, Palagi Vigano AV, Grützmacher EB, Vallejos-Penaloza G, Costa V, Martinez-Magallanes D, Vaz de Macedo A, de Paula-Garcia WN, Schwartz DS, Fregni F, and Pacheco-Barrios K
- Abstract
Background: Phantom limb pain (PLP) is highly prevalent after amputation. However, the influence of non-painful sensations (PLS) remains unclear. This study examines the PLP-PLS index as a novel tool to differentiate PLP from PLS and explores the association of clinical factors with the index., Methods: We conducted a cross-sectional analysis of baseline data from 112 participants in a previous factorial trial in patients with unilateral traumatic lower limb amputation. Linear regression models were used to examine the associations between the index and various demographic, psychological and clinical factors. Logistic and Poisson regression, and e-value calculation were utilized for sensitivity analyses., Results: Adjusted multivariable linear regression models demonstrated significant associations of phantom movement sensation (β: -1.532; 95% CI: -2.615 to -0.449; p = 0.006) and time since amputation (β: 0.005; 95% CI: 0.0006 to 0.0101; p = 0.026) with the PLP-PLS index. These findings were confirmed by multivariable logistic regression (phantom movement sensation OR: 0.469; 95% CI: 0.200 to 1.099, p = 0.082; time since amputation OR: 1.003; 95% CI: 1.00003 to 1.007; p = 0.048) and sensitivity analyses., Conclusions: Time since amputation and phantom movement sensation likely reflect distinct phenotypes and potential mechanisms for PLP and PLS. The PLP-PLS index is a promising clinical tool for selecting therapies to prevent/treat PLP and for measuring treatment effects to modulate phantom pain. These findings emphasize the importance of understanding the mechanisms underlying PLP and PLS for improving clinical management and guiding future research., Competing Interests: The authors declare no conflicts of interest.
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- 2024
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24. Improved all-cause mortality with left bundle branch area pacing compared to biventricular pacing in cardiac resynchronization therapy: a meta-analysis.
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Diaz JC, Gabr M, Tedrow UB, Duque M, Aristizabal J, Marin J, Niño C, Bastidas O, Koplan BA, Hoyos C, Matos CD, Hincapie D, Pacheco-Barrios K, Alviz I, Steiger NA, Kapur S, Tadros TM, Zei PC, Sauer WH, and Romero JE
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- Humans, Bundle-Branch Block therapy, Bundle-Branch Block mortality, Hospitalization statistics & numerical data, Risk Assessment, Stroke Volume physiology, Survival Rate, Treatment Outcome, Cardiac Resynchronization Therapy methods, Cause of Death, Heart Failure mortality, Heart Failure therapy
- Abstract
Background: Left bundle branch area pacing (LBBAP) has emerged as a physiological alternative pacing strategy to biventricular pacing (BIVP) in cardiac resynchronization therapy (CRT). We aimed to assess the impact of LBBAP vs. BIVP on all-cause mortality and heart failure (HF)-related hospitalization in patients undergoing CRT., Methods: Studies comparing LBBAP and BIVP for CRT in patients with HF with reduced left ventricular ejection fraction (LVEF) were included. The coprimary outcomes were all-cause mortality and HF-related hospitalization. Secondary outcomes included procedural and fluoroscopy time, change in QRS duration, and change in LVEF., Results: Thirteen studies (12 observational and 1 RCT, n = 3239; LBBAP = 1338 and BIVP = 1901) with a mean follow-up duration of 25.8 months were included. Compared to BIVP, LBBAP was associated with a significant absolute risk reduction of 3.2% in all-cause mortality (9.3% vs 12.5%, RR 0.7, 95% CI 0.57-0.86, p < 0.001) and an 8.2% reduction in HF-related hospitalization (11.3% vs 19.5%, RR 0.6, 95% CI 0.5-0.71, p < 0.00001). LBBAP also resulted in reductions in procedural time (mean weighted difference- 23.2 min, 95% CI - 42.9 to - 3.6, p = 0.02) and fluoroscopy time (- 8.6 min, 95% CI - 12.5 to - 4.7, p < 0.001) as well as a significant reduction in QRS duration (mean weighted difference:- 25.3 ms, 95% CI - 30.9 to - 19.8, p < 0.00001) and a greater improvement in LVEF of 5.1% (95% CI 4.4-5.8, p < 0.001) compared to BIVP in the studies that reported these outcomes., Conclusion: In this meta-analysis, LBBAP was associated with a significant reduction in all-cause mortality as well as HF-related hospitalization when compared to BIVP. Additional data from large RCTs is warranted to corroborate these promising findings., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2024
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25. A neural signature for brain compensation in stroke with EEG and TMS: Insights from the DEFINE cohort study.
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Lacerda GJ, Pacheco-Barrios K, Barbosa SP, Marques LM, Battistella L, and Fregni F
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- Humans, Male, Female, Middle Aged, Aged, Cross-Sectional Studies, Cohort Studies, Recovery of Function physiology, Brain physiopathology, Evoked Potentials, Motor physiology, Stroke Rehabilitation methods, Adult, Upper Extremity physiopathology, Hand Strength physiology, Transcranial Magnetic Stimulation methods, Electroencephalography methods, Stroke physiopathology
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Objective: This study aimed to explore the relationships between potential neurophysiological biomarkers and upper limb motor function recovery in stroke patients, specifically focusing on combining two neurophysiological markers: electroencephalography (EEG) and transcranial magnetic stimulation (TMS)., Methods: This cross-sectional study analyzed neurophysiological, clinical, and demographical data from 102 stroke patients from the DEFINE cohort. We searched for correlations of EEG and TMS measurements combined to build a prediction model for upper limb motor functionality, assessed by five outcomes, across five assessments: Fugl-Meyer Assessment (FMA), Handgrip Strength Test (HST), Finger Tapping Test (FTT), Nine-Hole Peg Test (9HPT), and Pinch Strength Test (PST)., Results: Our multivariate models agreed on a specific neural signature: higher EEG Theta/Alpha ratio in the frontal region of the lesioned hemisphere is associated with poorer motor outcomes, while increased MEP amplitude in the non-lesioned hemisphere correlates with improved motor function. These relationships are held across all five motor assessments, suggesting the potential of these neurophysiological measures as recovery biomarkers., Conclusion: Our findings indicate a potential neural signature of brain compensation in which lower frequencies of EEG power are increased in the lesioned hemisphere, and lower corticospinal excitability is also increased in the non-lesioned hemisphere. We discuss the meaning of these findings in the context of motor recovery in stroke., (Copyright © 2024 Elsevier Masson SAS. All rights reserved.)
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- 2024
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26. Noninvasive Neuromodulation Combined With Rehabilitation Therapy Improves Balance and Gait Speed in Patients With Stroke: A Systematic Review and Network Meta-analysis.
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Tangjade A, Suputtitada A, Pacheco-Barrios K, and Fregni F
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- Humans, Combined Modality Therapy, Stroke complications, Stroke physiopathology, Gait Disorders, Neurologic rehabilitation, Gait Disorders, Neurologic etiology, Randomized Controlled Trials as Topic, Stroke Rehabilitation methods, Walking Speed, Transcranial Magnetic Stimulation methods, Postural Balance physiology, Network Meta-Analysis, Transcranial Direct Current Stimulation methods
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Objective: This study aimed to determine repetitive transcranial magnetic stimulation, transcranial direct current stimulation, and cranial nerve noninvasive neuromodulation affect functional balance, gait speed, and walking cadence in stroke patients., Methods: We searched PubMed, Embase, Cochrane, and Scopus (June 22, 2022) for randomized controlled trials. Three reviewers independently performed data extraction and assessed the risk of bias. Network and pairwise meta-analyses were performed to assess indirect and direct comparisons., Results: We included 34 studies ( N = 915 patients). Sixty percent had moderate-to-high methodological quality. The meta-analyses showed positive effects of repetitive transcranial magnetic stimulation combined with rehabilitation therapy compared with sham on gait speed, walking cadence, and balance function with weighted mean differences and 95% confidence interval of 0.08 (0.03 to 0.13), 7.16 (3.217 to 11.103), and 3.05 (0.52 to 5.57), respectively. Transcranial direct current stimulation showed improvement on the time up and go test (-0.88 [-1.68 to -0.08]). From the surface under the cumulative ranking analyses, repetitive transcranial magnetic stimulation is the best ranked treatment for gait speed and functional balance improvement compared with transcranial direct current stimulation and sham interventions. There were not enough studies to include cranial nerve noninvasive neuromodulation in the meta-analysis., Conclusions: Walking cadence and speed, functional balance significantly improved after repetitive transcranial magnetic stimulation with short-term effects, which were superior to that of transcranial direct current stimulation and sham treatments. Transcranial direct current stimulation showed short-term beneficial effects on the Time Up and Go test., Competing Interests: Financial disclosure statements have been obtained, and no conflicts of interest have been reported by the authors or by any individuals in control of the content of this article., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2024
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27. Evidence of bottom-up homeostatic modulation induced taVNS during emotional and Go/No-Go tasks.
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Camargo L, Pacheco-Barrios K, Gianlorenço AC, Menacho M, Choi H, Song JJ, and Fregni F
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- Humans, Male, Female, Adult, Double-Blind Method, Young Adult, Executive Function physiology, Alpha Rhythm physiology, Evoked Potentials physiology, Transcutaneous Electric Nerve Stimulation methods, Inhibition, Psychological, Emotions physiology, Vagus Nerve Stimulation methods, Electroencephalography methods
- Abstract
Bilateral transcutaneous auricular vagus nerve stimulation (taVNS) - a non-invasive neuromodulation technique - has been investigated as a safe and feasible technique to treat many neuropsychiatric conditions. such as epilepsy, depression, anxiety, and chronic pain. Our aim is to investigate the effect of taVNS on neurophysiological processes during emotional and Go/No-Go tasks, and changes in frontal alpha asymmetry. We performed a randomized, double-blind, sham-controlled trial with 44 healthy individuals who were allocated into two groups (the active taVNS group and the sham taVNS group). Subjects received one session of taVNS (active or sham) for 60 min. QEEG was recorded before and after the interventions, and the subjects were assessed while exposed to emotional conditions with sad and happy facial expressions, followed by a Go/No-Go trial. The results demonstrated a significant increase in N2 amplitude in the No-Go condition for the active taVNS post-intervention compared to the sham taVNS after adjusting by handedness, mood, and fatigue levels (p = 0.046), significantly reduced ERD during sad conditions after treatment (p = 0.037), and increased frontal alpha asymmetry towards the right frontal hemisphere during the emotional task condition (p = 0.046). Finally, we observed an interesting neural signature in this study that suggests a bottom-up modulation from brainstem/subcortical to cortical areas as characterized by improved lateralization of alpha oscillations towards the frontal right hemisphere, and changes in ERP during emotional and Go/No-Go tasks that suggests a better subcortical response to the tasks. Such bottom-up effects may mediate some of the clinical effects of taVNS., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2024
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28. Psychological factors modulate quantitative sensory testing measures in fibromyalgia patients: a systematic review and meta-regression analysis.
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Carneiro AM, Pacheco-Barrios K, Andrade MF, Martinez-Magallanes D, Pichardo E, Caumo W, and Fregni F
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Objective: Considering the growing evidence that psychological variables might contribute to fibromyalgia syndrome (FMS), our study aims to understand the impact of psychological factors in quantitative sensory testing (QST) in FMS patients by performing a systematic review with metanalysis., Methods: A systematic search was carried out in Pubmed/MEDLINE, EMBASE, Web of Science, and PsycINFO databases for records up until January 2024. We included 20 studies (n = 1623, 16 RCTs, and four non-RCTs) with low or moderate risk of bias included., Results: From non-randomized evidence, our meta-analysis found a baseline relationship between anxiety, depression, and pain catastrophizing and QST measures in FMS patients. Higher pain catastrophizing levels were associated with less efficient CPM. Higher anxiety and depression were associated with lower PT. Randomized evidence showed a statistically significant increase in PT after fibromyalgia treatments (ES = 0.29, 95% CI 0.03 to 0.56). The effect was not influenced by treatment type. Moreover, we found that only anxiety levels before treatment negatively influenced the PT improvements after treatment., Conclusion: FMS patients with higher anxiety levels at baseline showed a smaller increase in PT after the intervention. Depression factor was not significant in either changes in anxiety or depression. Baseline anxiety levels should be monitored as possible confounders of QST measurements. Understanding how psychological factors and QST are related in FMS patients is critical for improving the syndrome's management and treatment.Protocol Registration: CRD42023429397., Competing Interests: Conflict of interest and source of funding: All the authors have no competing interests or other interests that might be perceived to influence the results and/or discussion reported in this paper. This research is supported by the National Institute of Health (R01 AT009491-01A1). The funding agencies have no role in the study. The views expressed here are the authors’ own and do not reflect the position or policy of the National Institutes of Health or any other part of the federal government., (Copyright © 2024 by the American Psychosomatic Society.)
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- 2024
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29. Transcutaneous vagus nerve stimulation effects on chronic pain: systematic review and meta-analysis.
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Costa V, Gianlorenço AC, Andrade MF, Camargo L, Menacho M, Arias Avila M, Pacheco-Barrios K, Choi H, Song JJ, and Fregni F
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Chronic pain is one of the major causes of disability with a tremendous impact on an individual's quality of life and on public health. Transcutaneous vagus nerve stimulation (tVNS) is a safe therapeutic for this condition. We aimed to evaluate its effects in adults with chronic pain. A comprehensive search was performed, including randomized controlled trials published until October 2023, which assessed the effects of noninvasive tVNS. Cohen's d effect size and 95% confidence intervals (CIs) were calculated, and random-effects meta-analyses were performed. Fifteen studies were included. The results revealed a mean effect size of 0.41 (95% CI 0.17-0.66) in favor of tVNS as compared with control, although a significant heterogeneity was observed (χ
2 = 21.7, df = 10, P = 0.02, I2 = 53.9%). However, when compared with nonactive controls, tVNS shows a larger effect size (0.79, 95% CI 0.25-1.33), although the number of studies was small (n = 3). When analyzed separately, auricular tVNS and cervical tVNS against control, it shows a significant small to moderate effect size, similar to that of the main analysis, respectively, 0.42 (95% CI 0.08-0.76, 8 studies) and 0.36 (95% CI 0.01-0.70, 3 studies). No differences were observed in the number of migraine days for the trials on migraine. This meta-analysis indicates that tVNS shows promise as an effective intervention for managing pain intensity in chronic pain conditions. We discuss the design of future trials to confirm these preliminary results, including sample size and parameters of stimulation., Competing Interests: H. Choi and J.-J. Song are directly associated with Neurive Co, a company developing neuromodulation technologies, such as taVNS, to treat common brain diseases. F. Fregni is supported by NIH grants and by a research grant and gift from Neurive to Spaulding Rehabilitation Hospital. Fregni is also a consultant for Neurive. The remaining authors have no conflicts of interest to declare., (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The International Association for the Study of Pain.)- Published
- 2024
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30. Brain compensatory mechanisms in depression and memory complaints in fibromyalgia: the role of theta oscillatory activity.
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Pacheco-Barrios K, Teixeira PEP, Martinez-Magallanes D, Neto MS, Pichardo EA, Camargo L, Lima D, Cardenas-Rojas A, and Fregni F
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- Humans, Female, Middle Aged, Cross-Sectional Studies, Adult, Male, Transcranial Magnetic Stimulation methods, Brain physiopathology, Fibromyalgia physiopathology, Fibromyalgia psychology, Memory Disorders physiopathology, Depression physiopathology, Theta Rhythm physiology
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Background: The different clinical presentations of fibromyalgia syndrome (FMS) might play independent roles in the unclear etiology of cognitive impairments and depressive symptoms seen in patients with FMS. Understanding how these clinical presentations are associated with the clinical and neurophysiological aspects of FMS is important for the development of effective treatments., Aim: To explore the relationship of memory complaints and depressive symptoms with the different clinical and neurophysiological characteristics of FMS., Methods: Cross-sectional data analysis from a randomized clinical trial. Baseline demographics and data on physical fitness, sleep, anxiety, depression, cortical excitability, and pain (clinical and mechanistic) from 63 subjects with FMS were used. Multiple linear and logistic association models were constructed., Results: Final regression models including different sets of predictions were statistically significant (P < .001), explaining approximately 50% of the variability in cognitive complaints and depression status. Older subjects had higher levels of anxiety, poorer sleep quality, lower motor threshold, and higher relative theta power in the central area and were more likely to have clinical depression. Higher anxiety, pain, and theta power were associated with a higher likelihood of memory complaints., Conclusion: Depression symptoms seem to be associated with transcranial magnetic stimulation-indexed motor threshold and psychosocial variables, whereas memory complaints are associated with pain intensity and higher theta oscillations. These mechanisms might be catalyzed or triggered by some behavioral and clinical features, such as older age, sleep disruption, and anxiety. The correlation with clinical variables suggests that the increasing of theta oscillations is a compensatory response in patients with FMS, which can be explored in future studies to improve the treatment of FMS., Trial Registration: ClinicalTrials.gov ID NCT03371225., (© The Author(s) 2024. Published by Oxford University Press on behalf of the American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
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- 2024
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31. Peri-ictal psychiatric manifestations in people with epilepsy: An umbrella review.
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Alva-Diaz C, Cabanillas-Lazo M, Navarro-Flores A, Martinez-Rivera RN, Valdeiglesias-Abarca M, Acevedo-Marino K, Pacheco-Barrios K, Ruiz-Garcia R, and Burneo J
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- Humans, Seizures, Epilepsy psychology, Epilepsy complications, Mental Disorders
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Objective: We aimed to conduct an umbrella review to summarize the existing evidence regarding the prevalence of peri-ictal psychiatric manifestations (PM) in people with epilepsy (PWE) including pre-ictal, ictal, and postictal stages., Methods: Databases were searched up to June 2023 for systematic reviews (SR) of observational studies that included patients with epilepsy peri-ictal PM. Data selection, data extraction, and risk of bias assessment (with the AMSTAR-2 instrument) were performed by two independent reviewers. We performed a narrative synthesis using previous guidelines. We used a self-developed decision table according to the GRADE system adapted for narrative outcomes if the certainty of outcomes was not determined by systematic review authors., Results: Four SRs were included comprising 66 primary studies (n = 10 217). Three SRs evaluated one period (pre-ictal, ictal, and postictal), and one did not determine it. During the pre-ictal period, the more prevalent symptom was confusion, although with a low certainty (due to the heterogeneity and serious risk of bias). One systematic review that only included case reports evaluated the ictal period, finding mood/anxiety disorders, psychosis, and personality changes. The postictal period included the most PM (anxiety: 45.0% and depressive symptoms: 43.0%), with very low certainty, due to risk of bias, potential publication bias, heterogeneity, and failure to report the confidence intervals., Significance: With very low certainty, epileptic periods are characterized by a wide spectrum of PM, being postictal symptoms the most prevalent, predominantly anxiety, and depressive symptoms. Further understanding of these PM of epilepsy could improve the attention of the people with epilepsy., Plain Language Summary: In this review of reviews, we summarize the frequency in which psychiatric manifestations occur in relation to an epileptic seizure. A total of 10 217 patients were reported in the reviews. The most common manifestations included symptoms of anxiety and depression, as well as changes in the normal behavior of the patient. These manifestations occurred most frequently right after the seizure finished., (© 2024 The Author(s). Epilepsia Open published by Wiley Periodicals LLC on behalf of International League Against Epilepsy.)
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- 2024
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32. Age as an Effect Modifier of the Effects of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Heart Rate Variability in Healthy Subjects.
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Gianlorenço AC, Pacheco-Barrios K, Daibes M, Camargo L, Choi H, Song JJ, and Fregni F
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Background : Evidence suggests that vagus nerve stimulation can modulate heart rate variability (HRV). However, there is a lack of mechanistic studies in healthy subjects assessing the effects of bilateral transcutaneous auricular vagus nerve stimulation (taVNS) on HRV. Our study aims to investigate how taVNS can influence the HRV response, including the influence of demographic variables in this response. Methods : Therefore, we conducted a randomized controlled study with 44 subjects, 22 allocated to active and 22 to sham taVNS. Results : Our results showed a significant difference between groups in the high-frequency (HF) metric. Active taVNS increased the HF metric significantly as compared to sham taVNS. Also, we found that age was a significant effect modifier of the relationship between taVNS and HF-HRV, as a larger increase in HF-HRV was seen in the older subjects. Importantly, there was a decrease in HF-HRV in the sham group. Conclusions : These findings suggest that younger subjects can adapt and maintain a constant level of HF-HRV regardless of the type of stimulation, but in the older subjects, only the active taVNS recipients were able to maintain and increase their HF-HRV. These results are important because they indicate that taVNS can enhance physiological regulation processes in response to external events.
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- 2024
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33. The Endogenous Pain Modulatory System as a Healing Mechanism: A Proposal on How to Measure and Modulate It.
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de Melo PS, Pacheco-Barrios K, Marduy A, Vasquez-Avila K, Simis M, Imamura M, Cardenas-Rojas A, Navarro-Flores A, Batistella L, and Fregni F
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Background: Chronic pain is highly burdening and multifactorial in etiology. The endogenous-pain-healing system restores body tissue to a non-painful state after an injury leading to pain, and its disruption could represent a relevant mechanism, especially for nursing interventions., Aim: To review the literature and summarize the results that support this hypothesis., Methods: We hypothesized that the mechanism behind this system mainly depends on the endogenous pain modulatory system (EPMS), which is responsible for inhibiting pain after tissue healing is complete and facilitating it when tissue damage is still present. Different biomarkers can quantify EPMS functioning. We reviewed the literature and included relevant information regarding this hypothesis., Results: First, conditioned pain modulation (CPM) measures pain inhibition and is a possible predictor for pain chronification. Second, motor cortex excitability measures the cortical control of the EPMS, which can be assessed through transcranial magnetic stimulation (using intracortical inhibition) or electroencephalography. Modifiable factors disrupt its functioning, such as sleep deprivation, medication overuse, and mental health status, but could be protective, such as exercise, certain medications, mind-body techniques, and non-invasive neuromodulation therapies. The acquisition of neurophysiological knowledge of how the chronicity of pain occurs and the EPMS involvement in this process may allow for better management of these patients., Conclusions: We raised the hypothesis that the impairment of the EPMS (altered cortical excitability and descendent pain modulation pathways) seems to be related to the disruption of the pain healing process and its chronicity. Further longitudinal studies evaluating the relationship between these biomarkers and chronic pain development are necessary., Competing Interests: Conflicts of InterestAll the authors declare no conflict of interest regarding this work., (© 2024 by the authors.)
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- 2024
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34. Neuropsychiatric drugs and a neurophysiological marker as predictors of health-related quality of life in patients with phantom limb pain.
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Costa V, Pacheco-Barrios K, Carolyna Gianlorenço A, and Fregni F
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Objective: To explore the relationship between sociodemographic, clinical, and neurophysiological variables and health-related quality of life (HR-QOL) of patients with phantom limb pain., Methods: This is a cross-sectional analysis of a previous clinical trial. Univariate and multivariate linear and logistic regression analyses were used to model the predictors of HR-QOL. We utilized a sequential modeling approach with increasing adjustment levels, controlling for age and sex, and other relevant clinical variables (time since amputation, level of amputation, and pain). HR-QOL was assessed by the SF-36 Health Survey and its eight subdomains., Results: We analyzed baseline data from 92 patients with lower-limb amputations. They were mostly male (63%), 45.2 ± 15.6 years, with a mean time since amputation of 82.7 ± 122.4 months, and an overall SF-36 score of 55.9 ± 21.5. We found an association between intracortical facilitation in the affected hemisphere (ICF), gabapentin usage, and HR-QOL. ICF is a predictor of better HRQOL, whereas gabapentin usage was associated with a poorer HR-QOL, with the main model explaining 13.4% of the variance in the outcome. For the SF-36 subdomains, ICF was also a positive predictor for social functioning, bodily pain, and vitality, while medication usage was associated with lower scores in mental health, general health perception, bodily pain, and vitality., Conclusion: We found firsthand two new independent predictors of HR-QOL in individuals with PLP, namely, the neurophysiological metric ICF and gabapentin usage. These results highlight the role of the motor cortex excitability in the HR-QOL and stress the need for treatments that favor the neuroplastic adaptation after amputation, for which ICF may be used as a possible marker., (© The Author(s) 2024. Published by Oxford University Press on behalf of the American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
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- 2024
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35. Exercise effects on cortical excitability in pain populations: A systematic review and meta-analysis.
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Pimenta DC, Cardenas-Rojas A, Camargo L, Lima D, Kelso J, Navarro-Flores A, Pacheco-Barrios K, and Fregni F
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- Humans, Transcranial Magnetic Stimulation, Randomized Controlled Trials as Topic, Pain Management methods, Evoked Potentials, Motor physiology, Chronic Pain therapy, Neuronal Plasticity physiology, Exercise physiology, Cortical Excitability physiology, Exercise Therapy methods
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Background: Transcranial Magnetic Stimulation (TMS) studies examining exercise-induced neuroplasticity in pain populations have produced contradictory findings. We conducted a systematic review to explore how exercise impacts cortical excitability in pain populations using TMS metrics. This review aims to summarize the effect sizes and to understand their sources of heterogeneity., Methods: We searched multiple databases from inception to December 2022. We included randomized controlled trials (RCTs) with any type of pain population, including acute and chronic pain; exercise interventions were compared to sham exercise or other active interventions. The primary outcomes were TMS metrics, and pain intensity was the secondary outcome. Risk of bias assessment was conducted using the Cochrane tool., Results: This review included five RCTs (n = 155). The main diagnoses were fibromyalgia and cervical dystonia. The interventions included submaximal contractions, aerobic exercise, physical therapy, and exercise combined with transcranial direct current stimulation. Three studies are considered to have a high risk of bias. All five studies showed significant pain improvement with exercise. The neurophysiological data revealed improvements in cortical excitability measured by motor-evoked potentials; standardized mean difference = 2.06, 95% confidence interval 1.35-2.78, I
2 = 19%) but no significant differences in resting motor threshold. The data on intracortical inhibition/facilitation (ICI/ICF) was not systematically analyzed, but one study (n = 45) reported higher ICI and lower ICF after exercise., Conclusions: These findings suggest that exercise interventions positively affect pain relief by modifying corticospinal excitability, but their effects on ICI/ICF are still unclear. While the results are inconclusive, they provide a basis for further exploration in this area of research; future studies should focus on establishing standardized TMS measurements and exercise protocols to ensure consistent and reliable findings. A large-scale RCT that examines various exercise interventions and their effects on cortical excitability could offer valuable insights to optimize its application in promoting neuroplasticity in pain populations., (© 2024 John Wiley & Sons Ltd.)- Published
- 2024
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36. The Impact of Obesity as a Peripheral Disruptor of Brain Inhibitory Mechanisms in Fibromyalgia: A Cross-Sectional Study.
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Fabris-Moraes W, Lacerda GJM, Pacheco-Barrios K, and Fregni F
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Background/Objective: Obesity, characterized by chronic inflammation, may serve as a surrogate marker for more dysfunctional peripheral inflammation, potentially exacerbating FM symptomatology. Given this premise, this study aimed to investigate the effects of obesity as an effect modifier on neural and clinical variables, specifically those indexing pain-compensatory mechanisms in FM symptoms. Methods: A cross-sectional study was conducted with 108 participants who underwent a standardized TMS protocol assessment to measure resting motor threshold (MT), intracortical facilitation (ICF), and intracortical inhibition (ICI). Clinical data were collected using Beck's Depression Index (BDI), PROMIS, the Brief Pain Inventory (BPI), and conditioned pain modulation (CPM). Linear regression models were used to explore the relationship between these variables while examining Body Mass Index (BMI) as a potential effect modifier. If it was found to be a modifier, we stratified the sample into two groups with a BMI cutoff of 30 and performed another regression model within the subgroups. Results: BMI was identified as an effect modifier in the relationships between ICI and BDI, PROMIS fatigue, and CPM and in MT versus CPM. After stratification, non-obese fibromyalgia subjects demonstrated significant correlations between clinical symptoms and CPM and ICI activity. However, these correlations were absent in the obese group, suggesting obesity disrupts pain mechanisms and their compensatory effects. Higher MT values were associated with weaker endogenous pain control, particularly evident in the obese group. Conclusions: Obesity appears to be a significant effect modifier and delineates two patient groups across multiple clinical and neural assessments of fibromyalgia. Additionally, it suggests a role for obesity in exacerbating fibromyalgia symptoms and disrupting physiological pain-inhibitory mechanisms.
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- 2024
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37. Adaptive and Compensatory Neural Signatures in Fibromyalgia: An Analysis of Resting-State and Stimulus-Evoked EEG Oscillations.
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Camargo L, Pacheco-Barrios K, Marques LM, Caumo W, and Fregni F
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This study aimed to investigate clinical and physiological predictors of brain oscillatory activity in patients with fibromyalgia (FM), assessing resting-state power, event-related desynchronization (ERD), and event-related synchronization (ERS) during tasks. We performed a cross-sectional analysis, including clinical and neurophysiological data from 78 subjects with FM. Multivariate regression models were built to explore predictors of electroencephalography bands. Our findings show a negative correlation between beta oscillations and pain intensity; fibromyalgia duration is positively associated with increased oscillatory power at low frequencies and in the beta band; ERS oscillations in the theta and alpha bands seem to be correlated with better symptoms of FM; fatigue has a signature in the alpha band-a positive relationship in resting-state and a negative relationship in ERS oscillations. Specific neural signatures lead to potential clusters of neural adaptation, in which beta oscillatory activity in the resting state represents a more adaptive activity when pain levels are low and stimulus-evoked oscillations at lower frequencies are likely brain compensatory mechanisms. These neurophysiological changes may help to understand the impact of long-term chronic pain in the central nervous system and the descending inhibitory system in fibromyalgia subjects.
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- 2024
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38. The impact of education level and socioeconomic status on the association between depressive symptoms and memory in an older population in Latin America: An exploratory analysis from the Brazilian Longitudinal Study of Aging (ELSI-BRAZIL).
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Loss K, Fandino W, Almarie B, Bazan-Perkins B, Minetto J, Aranis N, Monaco T, Aladab A, Pacheco-Barrios K, and Fregni F
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Purpose: The globally increasing older population raises concerns about age-related conditions, including cognitive impairment and depressive symptoms. In Latin America, nearly one-third of the population is affected by either of these conditions. However, data investigating the association between cognitive impairment and depressive symptoms, particularly in Brazil, are limited to small-scale studies that have not carefully examined the critical effects of variables such as education level and socioeconomic status on this relationship. We aimed at exploring this association in a representative population-based cohort., Methods: We used the Brazilian Longitudinal Study of Aging (ELSI-BRAZIL) database to examine the relationship between depressive symptoms and cognitive impairment in Brazilian older adults, adjusted for potential confounders. Direct acyclic graphs and multivariable linear regression were used to build our model. Depressive symptoms were measured using a short version of the Center for Epidemiologic Studies Scale (CES D-8), and combined memory recall test as a surrogate of cognitive impairment., Results: The study included 8280 participants. Only education level was identified as a confounder for the relationship between memory loss and depressive symptoms. After adjusting for age, sex, and education level, there was strong evidence for a negative association between depressive symptoms and memory performance. For every 5-unit increase in the CES D-8 score, there was a reduction in memory capacity, translating to a loss of approximately one word in the combined words recall test (mean - 0.18, 95% CI -0.22; -0.15, P < 0.001). In addition, we found strong evidence for an interaction between socioeconomic status and depressive symptoms. Subjects belonging to medium socioeconomic status (SES) showed more pronounced memory decline, when compared to those with lower SES (mean - 0.28, 95% CI -0.42 to -0.14, P < 0.001)., Conclusions: In adults aged over 50, after adjusting for sex, age, and educational level, a 5-unit increase in CES D-8 score is associated with loss of one point in the combined memory recall test. This association seems to be confounded by educational level and significantly modified by socioeconomic status., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2023 Published by Elsevier Inc. CC BY-NC-ND 4.0.)
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- 2024
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39. Preventing posttraumatic stress disorder following childbirth: a systematic review and meta-analysis.
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Dekel S, Papadakis JE, Quagliarini B, Pham CT, Pacheco-Barrios K, Hughes F, Jagodnik KM, and Nandru R
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- Humans, Female, Pregnancy, Cognitive Behavioral Therapy methods, Stress Disorders, Post-Traumatic prevention & control, Stress Disorders, Post-Traumatic therapy, Stress Disorders, Post-Traumatic psychology, Parturition psychology
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Objective: Women can develop posttraumatic stress disorder in response to experienced or perceived traumatic, often medically complicated, childbirth; the prevalence of these events remains high in the United States. Currently, no recommended treatment exists in routine care to prevent or mitigate maternal childbirth-related posttraumatic stress disorder. We conducted a systematic review and meta-analysis of clinical trials that evaluated any therapy to prevent or treat childbirth-related posttraumatic stress disorder., Data Sources: PsycInfo, PsycArticles, PubMed (MEDLINE), ClinicalTrials.gov, CINAHL, ProQuest, Sociological Abstracts, Google Scholar, Embase, Web of Science, ScienceDirect, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched for eligible trials published through September 2023., Study Eligibility Criteria: Trials were included if they were interventional, if they evaluated any therapy for childbirth-related posttraumatic stress disorder for the indication of symptoms or before posttraumatic stress disorder onset, and if they were written in English., Methods: Independent coders extracted the sample characteristics and intervention information of the eligible studies and evaluated the trials using the Downs and Black's quality checklist and Cochrane's method for risk of bias evaluation. Meta-analysis was conducted to evaluate pooled effect sizes of secondary and tertiary prevention trials., Results: A total of 41 studies (32 randomized controlled trials, 9 nonrandomized trials) were reviewed. They evaluated brief psychological therapies including debriefing, trauma-focused therapies (including cognitive behavioral therapy and expressive writing), memory consolidation and reconsolidation blockage, mother-infant-focused therapies, and educational interventions. The trials targeted secondary preventions aimed at buffering childbirth-related posttraumatic stress disorder usually after traumatic childbirth (n=24), tertiary preventions among women with probable childbirth-related posttraumatic stress disorder (n=14), and primary prevention during pregnancy (n=3). A meta-analysis of the combined randomized secondary preventions showed moderate effects in reducing childbirth-related posttraumatic stress disorder symptoms when compared with usual treatment (standardized mean difference, -0.67; 95% confidence interval, -0.92 to -0.42). Single-session therapy within 96 hours of birth was helpful (standardized mean difference, -0.55). Brief, structured, trauma-focused therapies and semi-structured, midwife-led, dialogue-based psychological counseling showed the largest effects (standardized mean difference, -0.95 and -0.91, respectively). Other treatment approaches (eg, the Tetris game, mindfulness, mother-infant-focused treatment) warrant more research. Tertiary preventions produced smaller effects than secondary prevention but are potentially clinically meaningful (standardized mean difference, -0.37; -0.60 to -0.14). Antepartum educational approaches may help, but insufficient empirical evidence exists., Conclusion: Brief trauma-focused and non-trauma-focused psychological therapies delivered early in the period following traumatic childbirth offer a critical and feasible opportunity to buffer the symptoms of childbirth-related posttraumatic stress disorder. Future research that integrates diagnostic and biological measures can inform treatment use and the mechanisms at work., (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
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- 2024
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40. Chikungunya crisis in the Americas: a comprehensive call for research and innovation.
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Pegado R, Mendes Neto NN, Pacheco-Barrios K, and Fregni F
- Abstract
Competing Interests: Authors declares no conflicts of interest.
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- 2024
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41. Developing transcranial direct current stimulation as a treatment for phantom limb pain: from pilot mechanistic studies to large clinical studies.
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Zhang XC, Pacheco-Barrios K, and Fregni F
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- 2024
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42. Enhancing Dissemination and Understanding in Clinical Research Protocols: Optimizing Visual Communication in a Phantom Limb Pain Clinical Trial.
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Zhang XC, Pacheco-Barrios K, and Fregni F
- Abstract
Competing Interests: Conflicts of Interest The authors declare no conflict of interest.
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- 2024
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43. Cross-sectional and longitudinal analysis of conditioned pain modulation and pain in fibromyalgia: CPM as an effect modifier of pain changes over time.
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Castelo-Branco L, Pacheco-Barrios K, Cardenas-Rojas A, de Melo PS, Gianlorenco AC, Gonzalez-Mego P, Marduy A, Shaik ES, Teixeira P, Caumo W, and Fregni F
- Subjects
- Humans, Cross-Sectional Studies, Female, Longitudinal Studies, Male, Middle Aged, Adult, Time Factors, Surveys and Questionnaires, Pain Management, Fibromyalgia, Pain Measurement, Quality of Life
- Abstract
Background and Purpose: Fibromyalgia (FM) is associated with altered descending pain modulatory pathways, which can be assessed through Conditioned Pain Modulation (CPM). In this study, we aimed to explore the relationship between CPM and self-reported baseline characteristics in patients with fibromyalgia. We also performed a longitudinal analysis exploring CPM as a potential predictor of clinical improvement over time in individuals with FM., Methods: We performed cross-sectional univariable and multivariable analyses of the relationship between CPM and other variables in 41 FM patients. We then performed longitudinal analyses, building linear mixed effects models with pain in the Visual Analogue Scale (VAS) as the dependent variable, and testing for the interaction between time and CPM. We also tested the interaction between CPM and time in models using other outcomes, such as the revised Fibromyalgia Impact Questionnaire (FIQR) and Quality of Life Scale (QOLs)., Results: We found no association between CPM and other demographic and clinical variables in the univariable analysis. We found a statistically significant association in the multivariable linear regression model between CPM and the QOLs at baseline, after controlling for age, sex, and duration of symptoms. In the longitudinal analyses, we found that CPM is an effect modifier for clinical improvement over time for the pain VAS, QOLs and FIQR: individuals with low-efficient CPM at baseline have a different (improved) pattern of response over time when compared to those with high-efficient CPM., Conclusions: Our findings suggest that CPM is not a reliable biomarker of clinical manifestations in chronic pain patients during cross-sectional assessments. However, our results are consistent with previous findings that CPM can be used to predict the evolution of clinical pain over time. We expect that our findings will help in the selection of patients with the best profile to respond to specific interventions and assist clinicians in tailoring pain treatments., Competing Interests: Conflict of interest disclosure Authors state no conflict of interest.
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- 2024
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44. Resting-state electroencephalography delta and theta bands as compensatory oscillations in chronic neuropathic pain: a secondary data analysis.
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Barbosa SP, Junqueira YN, Akamatsu MA, Marques LM, Teixeira A, Lobo M, Mahmoud MH, Omer WE, Pacheco-Barrios K, and Fregni F
- Abstract
Chronic neuropathic pain (CNP) remains a significant clinical challenge, with complex neurophysiological underpinnings that are not fully understood. Identifying specific neural oscillatory patterns related to pain perception and interference can enhance our understanding and management of CNP. To analyze resting electroencephalography data from individuals with chronic neuropathic pain to explore the possible neural signatures associated with pain intensity, pain interference, and specific neuropathic pain characteristics. We conducted a secondary analysis from a cross-sectional study using electroencephalography data from a previous study, and Brief Pain Inventory from 36 patients with chronic neuropathic pain. For statistical analysis, we modeled a linear or logistic regression by dependent variable for each model. As independent variables, we used electroencephalography data with such brain oscillations: as delta, theta, alpha, and beta, as well as the oscillations low alpha, high alpha, low beta, and high beta, for the central, frontal, and parietal regions. All models tested for confounding factors such as age and medication. There were no significant models for Pain interference in general activity, walking, work, relationships, sleep, and enjoyment of life. However, the model for pain intensity during the past four weeks showed decreased alpha oscillations, and increased delta and theta oscillations were associated with decreased levels of pain, especially in the central area. In terms of pain interference in mood, the model showed high oscillatory Alpha signals in the frontal and central regions correlated with mood impairment due to pain. O ur models confirm recent findings proposing that lower oscillatory frequencies, likely related to subcortical pain sources, may be associated with brain compensatory mechanisms and thus may be associated with decreased pain levels. On the other hand, higher frequencies, including alpha oscillations, may disrupt top-down compensatory mechanisms., Competing Interests: Conflicts of interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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- 2024
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45. Using Home-based, Remotely Supervised, Transcranial Direct Current Stimulation for Phantom Limb Pain.
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Pacheco-Barrios K, Martinez-Magallanes D, Naqui CX, Daibes M, Pichardo E, Cardenas-Rojas A, Crandell D, Dua A, Datta A, Caumo W, and Fregni F
- Subjects
- Humans, Brain, Transcranial Direct Current Stimulation methods, Phantom Limb therapy
- Abstract
Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that uses low-amplitude direct currents to alter cortical excitability. Previous trials have established the safety and tolerability of tDCS, and its potential to mitigate symptoms. However, the effects are cumulative, making it more difficult to have adherence to the treatment since frequent visits to the clinic or outpatient center are required. Moreover, the time needed for transportation to the center and the related expenses limit the accessibility of the treatment for many participants. Following guidelines for remotely supervised transcranial direct current stimulation (RS-tDCS) implementation, we propose a protocol designed for remotely supervised and home-based participation that uses specific devices and materials modified for patient use, with real-time monitoring by researchers through an encrypted video conferencing platform. We have developed detailed instructional materials and structured training procedures to allow for self- or proxy-administration while supervised remotely in real time. This protocol has a specific design to have a series of checkpoints during training and execution of the visit. This protocol is currently in use in a large pragmatic study of RS-tDCS for phantom limb pain (PLP). In this article, we will discuss the operational challenges of conducting a home-based RS-tDCS session and show methods to enhance its efficacy with supervised sessions.
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- 2024
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46. Transauricular Vagus Nerve Stimulation (taVNS) enhances Conditioned Pain Modulation (CPM) in healthy subjects: A randomized controlled trial.
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Pacheco-Barrios K, Gianlorenco AC, Camargo L, Andrade MF, Choi H, Song JJ, and Fregni F
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- Humans, Male, Adult, Female, Pain Management methods, Healthy Volunteers, Pain, Young Adult, Conditioning, Psychological physiology, Vagus Nerve Stimulation methods
- Abstract
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: H.C. and J.S. are directly associated with Neurive Co, a company developing neuromodulation technologies, such as taVNS, to treat common brain diseases. Neurive funds research at the Spaulding Neuromodulation Center. F.F. is a consultant for Neurive.
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- 2024
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47. Non-invasive sound wave brain stimulation with Transcranial Pulse Stimulation (TPS) improves neuropsychiatric symptoms in Alzheimer's disease.
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Shinzato GT, Assone T, Sandler PC, Pacheco-Barrios K, Fregni F, Radanovic M, Forlenza OV, and Battistella LR
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- Humans, Male, Female, Aged, Prospective Studies, Aged, 80 and over, Treatment Outcome, Neuropsychological Tests, Cognition physiology, Alzheimer Disease therapy, Transcranial Direct Current Stimulation methods
- Abstract
Background: This study explores Transcranial Pulse Stimulation (TPS) as a potential non-invasive treatment for Alzheimer's disease (AD), focusing on its impact on cognitive functions and behavioral symptoms., Methods: In a prospective, one-arm open-label trial, ten patients with mild to moderate dementia due to AD were assessed using the Alzheimer's Disease Assessment Scale (ADAS-Cog), Neuropsychiatric Inventory (NPI), Pfeffer Functional Activities Questionnaire, and Zarit Caregiver Burden Interview. Assessments occurred at 30- and 90-days post-treatment. The TPS protocol consisted of 10 sessions over five weeks, using the Neurolith® device to deliver 6000 focused shockwave pulses at 0.25 mJ/mm2 and a frequency of 4 Hz., Results: TPS significantly reduced neuropsychiatric symptoms, with NPI scores decreasing by 23.9 points (95% CI: -39.19 to -8.61, p = 0.0042) after 30 days, and by 18.9 points (95% CI: -33.49 to -2.91, p = 0.022) after 90 days. These changes had large effect sizes (Cohen's dz = 1.43 and dz = 0.94, respectively). A decreasing trend was observed in the ADAS-Cog score (-3.6, 95% CI: -7.18 to 0.00, p = 0.05) after 90 days, indicating a potential reduction in cognitive impairment, though not statistically significant., Conclusion: The preliminary results indicate that TPS treatment leads to significant improvement in neuropsychiatric symptoms in AD patients, showing promise as a therapeutic approach for AD. Further research is needed to fully establish its effectiveness, especially concerning cognitive functions., Competing Interests: Declaration of competing interest None, (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
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- 2024
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48. Brain-heart interactions in fibromyalgia syndrome.
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Costa V, Gianlorenço AC, Pacheco-Barrios K, and Fregni F
- Abstract
Competing Interests: Conflict of Interest The authors declare no conflicting interests.
- Published
- 2024
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49. Distinct patterns of metabolic motor cortex activity for phantom and residual limb pain in people with amputations: A functional near-infrared spectroscopy study.
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Simis M, Marques LM, Barbosa SP, Sugawara AT, Sato JR, Pacheco-Barrios K, Battistella LR, and Fregni F
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- Humans, Adult, Middle Aged, Spectroscopy, Near-Infrared, Brazil, Amputation, Surgical, Lower Extremity, Motor Cortex, Phantom Limb rehabilitation
- Abstract
Background: Phantom pain limb (PLP) has gained more attention due to the large number of people with amputations around the world and growing knowledge of the pain process, although its mechanisms are not completely understood., Objectives: The aim of this study was to understand, in patients with amputations, the association between PLP and residual limb pain (RLP), and the brain metabolic response in cortical motor circuits, using functional near-infrared spectroscopy (fNIRS)., Methods: Sixty participants were recruited from the rehabilitation program in São Paulo, Brazil. Included patients were aged over 18 years, with traumatic unilateral lower-limb amputation, with PLP for at least 3 months after full recovery from amputation surgery. PLP and RLP levels were measured using visual analogue scales. fNIRS was performed during motor execution and motor mirror tasks for 20 s. In order to highlight possible variables related to variation in pain measures, univariate linear regression analyses were performed for both experimental conditions, resulting in four fNIRS variables (two hemispheres x two experimental conditions). Later, in order to test the topographic specificity of the models, eight multivariate regression analyses were performed (two pain scales x two experimental conditions x two hemispheres), including the primary motor cortex (PMC) related channel as an independent variable as well as five other channels related to the premotor area, supplementary area, and somatosensory cortex. All models were controlled for age, sex, ethnicity, and education., Results: We found that: i) there is an asymmetric metabolic activation during motor execution and mirror task between hemispheres (with a predominance that is ipsilateral to the amputated limb), ii) increased metabolic response in the PMC ipsilateral to the amputation is associated with increased PLP (during both experimental tasks), while increased metabolic response in the contralateral PMC is associated with increased RLP (during the mirror motor task only); ii) increased metabolic activity of the ipsilateral premotor region is associated with increased PLP during the motor mirror task; iii) RLP was only associated with higher metabolic activity in the contralateral PMC and lower metabolic activity in the ipsilateral inferior frontal region during motor mirror task, but PLP was associated with higher metabolic activity during both tasks., Conclusion: These results suggest there is both task and region specificity for the association between the brain metabolic response and the two different types of post-amputation pain. The metabolic predominance that is ipsilateral to the amputated limb during both tasks was associated with higher levels of PLP, suggesting a cortical motor network activity imbalance due to potential interhemispheric compensatory mechanisms. The present work contributes to the understanding of the underlying topographical patterns in the motor-related circuits associated with pain after amputations., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper, (Copyright © 2023. Published by Elsevier Masson SAS.)
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- 2024
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50. Factors associated with pain pressure threshold in both local and remote sites in knee osteoarthritis.
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Imamura M, Rebello-Sanchez I, Parente J, Marduy A, Vasquez-Avila K, Pacheco-Barrios K, Castelo-Branco L, Simis M, Battistella L, and Fregni F
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- Adult, Humans, Female, Prospective Studies, Cross-Sectional Studies, Pain diagnosis, Pain etiology, Pain Threshold, Osteoarthritis, Knee complications, Osteoarthritis, Knee diagnosis
- Abstract
Background: Knee osteoarthritis (KOA) is a prevalent condition, and its most frequent symptom is pain that often leads to disability. Pain sensitization is a core feature of KOA, and it can be measured through quantitative sensory testing protocols such as pain pressure threshold (PPT). However, there is a lack of understanding about the factors that may influence changes in PPTs in the KOA population., Objective: To explore the clinical and functional factors associated with PPTs in a sample of people with chronic KOA pain and to compare models of local (knees) and remote (thenar regions) sites., Design: Cross-sectional analysis of a prospective cohort., Setting: Primary care in public institution., Participants: 113 adults with KOA., Intervention: N/A., Main Outcome Measures: Multivariable regression analyses evaluating demographic, clinical, and functional variables that could be associated with local and remote PPTs (main outcomes) were performed., Results: Both thenar region (adjusted-R
2 : 0.29) and knee (adjusted-R2 : 0.45) models had the same significant negative association with being a female, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain levels (thenar: β: -0.15, p = .002; knee: β: -0.2, p < .001), and the 10-Meter Walking Test (thenar: β: -0.05, p = .038; knee: β: -0.08, p = .004). A small significant positive association with depressive symptoms was identified in both models, which acted as a confounder for WOMAC pain and was likely affected by unmeasured confounders., Conclusions: PPTs in KOA pain are associated with functional outcomes such as the 10-Meter Walking Test and activity-related pain intensity; thus more disability is associated with smaller pain thresholds. Similarity between models may suggest central sensitization., (© 2023 American Academy of Physical Medicine and Rehabilitation.)- Published
- 2024
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