1. Concentrated sugars and incidence of prostate cancer in a prospective cohort
- Author
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Miles, Fayth L, Neuhouser, Marian L, and Zhang, Zuo-Feng
- Subjects
Biomedical and Clinical Sciences ,Oncology and Carcinogenesis ,Clinical Research ,Prostate Cancer ,Aging ,Urologic Diseases ,Cancer ,Prevention ,Aged ,Beverages ,Diet ,Dietary Sucrose ,Feeding Behavior ,Fruit and Vegetable Juices ,Humans ,Male ,Middle Aged ,Proportional Hazards Models ,Prospective Studies ,Prostatic Neoplasms ,Risk Factors ,Sugars ,Sweetening Agents ,Added sugars ,Proportional hazards regression ,Prostate cancer risk ,Prospective cohorts ,Colorectal and Ovarian ,DHQ diet history questionnaire ,HR hazard ratio ,Lung ,PLCO Prostate ,PSA prostate-specific antigen ,Animal Production ,Food Sciences ,Nutrition and Dietetics ,Nutrition & Dietetics ,Animal production ,Food sciences ,Nutrition and dietetics - Abstract
The association between consumption of added or concentrated sugars and prostate cancer risk is unclear. We examined the association between concentrated sugars in beverages and desserts and prostate cancer risk among 22 720 men in the usual-care arm of the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial, enrolled during 1993-2001. After a median follow-up of 9 years, 1996 men were diagnosed with prostate cancer. Cox proportional hazards regression models were used to estimate hazard ratios (HR) for prostate cancer risk and 95 % CI, adjusting for potential confounding factors. Increased consumption of sugars from sugar-sweetened beverages was associated with increased risk of prostate cancer for men in the highest quartile of sugar consumption (HR: 1·21; 95 % CI 1·06, 1·39), and there was a linear trend (P
- Published
- 2018