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44 results on '"PALECZNY, JUSTYNA"'

7. The Assessment of Activity of Antiseptic Agents against Biofilm of Staphylococcus aureus Measured with the Use of Processed Microscopic Images

Author

Krasowski, Grzegorz, primary, Migdał, Paweł, additional, Woroszyło, Marta, additional, Fijałkowski, Karol, additional, Chodaczek, Grzegorz, additional, Czajkowska, Joanna, additional, Dudek, Bartłomiej, additional, Nowicka, Joanna, additional, Oleksy-Wawrzyniak, Monika, additional, Kwiek, Bartłomiej, additional, Paleczny, Justyna, additional, Brożyna, Malwina, additional, and Junka, Adam, additional

Published
2022
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10. Investigation of the Associations of Novel Inflammatory Biomarkers—Systemic Inflammatory Index (SII) and Systemic Inflammatory Response Index (SIRI)—With the Severity of Coronary Artery Disease and Acute Coronary Syndrome Occurrence

Author

Dziedzic, Ewelina A., primary, Gąsior, Jakub S., additional, Tuzimek, Agnieszka, additional, Paleczny, Justyna, additional, Junka, Adam, additional, Dąbrowski, Marek, additional, and Jankowski, Piotr, additional

Published
2022
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18. The efficacy of antiseptic agents against staphylococcal biofilm can be quantitatively assessed with the use of processed microscopic images

Author

Krasowski, Grzegorz, primary, Migdał, Paweł, additional, Woroszyło, Marta, additional, Fijałkowski, Karol, additional, Chodaczek, Grzegorz, additional, Czajkowska, Joanna, additional, Dudek, Bartłomiej, additional, Nowicka, Joanna, additional, Oleksy-Wawrzyniak, Monika, additional, Kwiek, Bartłomiej, additional, Paleczny, Justyna, additional, Brożyna, Malwina, additional, and Junka, Adam, additional

Published
2021
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24. Screening Papaveraceae as Novel Antibiofilm Natural-Based Agents

Author

Zielińska, Sylwia, primary, Dziągwa-Becker, Magdalena, additional, Junka, Adam, additional, Piątczak, Ewelina, additional, Jezierska-Domaradzka, Anna, additional, Brożyna, Malwina, additional, Paleczny, Justyna, additional, Sobiecka, Aleksandra, additional, Słupski, Wojciech, additional, Mess, Eleonora, additional, Kucharski, Mariusz, additional, Çiçek, Serhat Sezai, additional, Zidorn, Christian, additional, and Matkowski, Adam, additional

Published
2021
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27. 3D Printing of Thermoresponsive Hydrogel Laden with an Antimicrobial Agent towards Wound Healing Applications

Author

Nizioł, Martyna, Paleczny, Justyna, Junka, Adam, Shavandi, Amin, Dawiec-Liśniewska, Anna, Podstawczyk, Daria, Nizioł, Martyna, Paleczny, Justyna, Junka, Adam, Shavandi, Amin, Dawiec-Liśniewska, Anna, and Podstawczyk, Daria

Abstract

Thermoresponsive hydrogel-based wound dressings with an incorporated antimicrobial agent can be fabricated employing 3D printing technology. A novel printable ink containing poly(N-isopropylacrylamide) (PNIPAAm) precursors, sodium alginate (ALG), methylcellulose (MC) that is laden with a mixture of octenidine dihydrochloride and 2-phenoxyethanol (Octenisept®, OCT) possess accurate printability and shape fidelity. This study also provides the protocol of ink’s use for the 3D printing of hydrogel scaffolds. The hydrogel’s physicochemical properties and drug release profiles from the hydrogel specimens to the external solution have been determined at two temperatures (20 and 37 °C). The release test showed a sustained OCT delivery into ultrapure water and the PBS solution. The temperature-responsive hydrogel exhibited antimicrobial activity against Staphylococcus aureus, Candida albicans, and Pseudomonas aeruginosa and demonstrated non-cytotoxicity towards fibroblasts. The thermoresponsive behavior along with biocompatibility, antimicrobial activity, and controlled drug release make this hydrogel a promising class of materials for wound dressing applications., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2021

28. OCENA PRZYDATNOŚCI IN VITRO OPATRUNKU LIPIDOKOLOIDOWEGO ZAWIERAJĄCEGO JONY SREBRA DO ERADYKACJI BIOFILMÓW MIESZANYCH PSEUDOMONAS AERUGINOSA I STAPHYLOCOCCUS AUREUS TWORZĄCYCH SIĘ W ZRÓŻNICOWANYCH WARUNKACH HODOWLANYCH.

Author

BARTOSZEWICZ, MARZENNA, JUNKA, ADAM, PALECZNY, JUSTYNA, MIGDAŁ, PAWEŁ, DZIĘGIELEWSKA, MONIKA, CZAJKOWSKA, JOANNA, WOREK, MICHAŁ, and DUDEK, BARTŁOMIEJ

Abstract

Copyright of Forum Zakażeń is the property of Evereth Publishing Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022
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32. Clinical Trials of Probiotic Strains in Selected Disease Entities

Author

Dudek-Wicher, Ruth, Junka, Adam, Paleczny, Justyna, and Bartoszewicz, Marzenna

Subjects
Article Subject
Abstract

Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. Although their mechanism of action is not clearly explained, it is known that they positively modulate the immune system, which leads to immunity potentiation. A number of studies prove that probiotics strengthen cognitive functions, reduce anxiety, and regulate the lipid metabolism in the human body. Probiotics used in humans are most often of the Lactobacillus and Bifidobacterium species. However, as more research is conducted, new species with beneficial, probiotic properties are being discovered. This paper provides a review of available information about the influence of probiotics on human health. It summarizes the current knowledge on the mechanism of action of probiotics as well as clinical trial results proving their efficacy in allergic, neurodegenerative, and cardiac diseases. This review also discusses the data concerning the safety of probiotics in clinical treatment.

Published
2020
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34. In Vitro Evaluation of Polihexanide, Octenidine and NaClO/HClO-Based Antiseptics against Biofilm Formed by Wound Pathogens

Author

Krasowski, Grzegorz, primary, Junka, Adam, additional, Paleczny, Justyna, additional, Czajkowska, Joanna, additional, Makomaska-Szaroszyk, Elżbieta, additional, Chodaczek, Grzegorz, additional, Majkowski, Michał, additional, Migdał, Paweł, additional, Fijałkowski, Karol, additional, Kowalska-Krochmal, Beata, additional, and Bartoszewicz, Marzenna, additional

Published
2021
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35. Potential of Novel Bacterial Cellulose Dressings Chemisorbed with Antiseptics for the Treatment of Oral Biofilm Infections

Author

Krasowski, Grzegorz, primary, Wicher-Dudek, Ruth, additional, Paleczny, Justyna, additional, Bil-Lula, Iwona, additional, Fijałkowski, Karol, additional, Sedghizadeh, Parish Paymon, additional, Szymczyk, Patrycja, additional, Dudek, Bartłomiej, additional, Bartoszewicz, Marzenna, additional, and Junka, Adam, additional

Published
2019
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38. Modifications of bacterial cellulose in wound care.

Author

Paleczny, Justyna, Brożyna, Malwina, Junka, Adam, Bartoszewicz, Marzenna, and Dudek-Wicher, Ruth

Subjects
WOUND care, CHRONIC wounds & injuries, ANTIBACTERIAL agents, WOUND infections, ANTI-infective agents, ANTIBIOTICS, CELLULOSE, ESSENTIAL oils
Abstract

Copyright of Polimery w Medycynie is the property of Wroclaw Medical University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2021
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40. Skuteczność opatrunku UrgoClean® Ag Pad w eradykacji i sekwestracji in vitro drobnoustrojów będących czynnikiem etiologicznym zakażeń ran przewlekłych

Author

Bartoszewicz, Marzenna, primary, Junka, Adam, additional, Oleksy, Monika, additional, Dydak, Karolina, additional, Dudek, Bartłomiej, additional, Czajkowska, Joanna, additional, Chodaczek, Grzegorz, additional, Paleczny, Justyna, additional, Fijałkowski, Karol, additional, and Migdał, Paweł, additional

Published
2019
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42. PROFILAKTYKA ZAKAŻEŃ ODCEWNIKOWYCH U PACJENTÓW HEMODIALIZOWANYCH - PRZEGLĄD SUBSTANCJI STOSOWANYCH DO ZAMYKANIA CEWNIKÓW PERMANENTNYCH.

Author

PIĄTKOWSKA, ELŻBIETA, PALECZNY, JUSTYNA, DYDAK, KAROLINA, and BARTOSZEWICZ, MARZENNA

Abstract

Protection of vascular catheters for hemodialysis against colonization of microbes and development of catheter-related bloodstream infections require an administration of anticoagulants and antimicrobial substances into the lumen of the catheter. This paper reviews the compound solutions used for this purpose. [ABSTRACT FROM AUTHOR]

Published
2019
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43. ‘Cookies on a tray’: Superselective hierarchical microstructured poly(l-lactide) surface as a decoy for cells

Author

Kryszak, Bartłomiej, Szustakiewicz, Konrad, Dzienny, Paulina, Junka, Adam, Paleczny, Justyna, Szymczyk-Ziółkowska, Patrycja, Hoppe, Viktoria, Grzymajło, Michał, and Antończak, Arkadiusz

Abstract

In this research we developed a micro-sized hierarchical structures on a poly(l-lactide) (PLLA) surface. The obtained structures consist of round-shaped protrusions with a diameter of ~20 μm, a height of ~3 μm, and the distance between them ~30 μm. We explored the effect of structuring PLLA to design a non-cytotoxic material with increased roughness to encourage cells to settle on the surface. The PLLA films were prepared using the casting melt extrusion technique and were modified using ultra-short pulse irradiation – a femtosecond laser operating at λ = 1030 nm. A hierarchical microstructure was obtained resembling ‘cookies on a tray’. The cellular response of fibro- and osteoblasts cell lines was investigated. The conducted research has shown that the laser-modified surface is more conducive to cell adhesion and growth (compared to unmodified surface) to such an extent that allows the formation of highly-selectively patterns consisting of living cells. In contrast to eukaryotic cells, the pathogenic bacteria Staphylococcus aureuscovered modified and unmodified structures in an even, non-preferential manner. In turn, adhesion pattern of eukaryotic fungus Saccharomyces boulardiiresembled that of fibro- and osteoblast cells rather than that of Staphylococcus. The discovered effect can be used for fabrication of personalized and smart implants in regenerative medicine.

Published
2024
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44. In Vitro Susceptibility of Multi-Drug Resistant Klebsiella pneumoniae Strains Causing Nosocomial Infections to Fosfomycin. A Comparison of Determination Methods.

Author

Mączyńska, Beata, Paleczny, Justyna, Oleksy-Wawrzyniak, Monika, Choroszy-Król, Irena, Bartoszewicz, Marzenna, and Sajid, Andaleeb

Subjects
FOSFOMYCIN, KLEBSIELLA pneumoniae, KLEBSIELLA infections, NOSOCOMIAL infections, HOSPITAL laboratories, DRUG resistance in bacteria, CARBAPENEMS, COLISTIN
Abstract

Introduction: Over the past few decades, Klebsiella pneumoniae strains increased their pathogenicity and antibiotic resistance, thereby becoming a major therapeutic challenge. One of the few available therapeutic options seems to be intravenous fosfomycin. Unfortunately, the determination of sensitivity to fosfomycin performed in hospital laboratories can pose a significant problem. Therefore, the aim of the present research was to evaluate the activity of fosfomycin against clinical, multidrug-resistant Klebsiella pneumoniae strains isolated from nosocomial infections between 2011 and 2020, as well as to evaluate the methods routinely used in hospital laboratories to assess bacterial susceptibility to this antibiotic. Materials and Methods: 43 multidrug-resistant Klebsiella strains isolates from various infections were tested. All the strains had ESBL enzymes, and 20 also showed the presence of carbapenemases. Susceptibility was determined using the diffusion method (E-test) and the automated system (Phoenix), which were compared with the reference method (agar dilution). Results: For the reference method and for the E-test, the percentage of strains sensitive to fosfomycin was 65%. For the Phoenix system, the percentage of susceptible strains was slightly higher and stood at 72%. The percentage of fosfomycin-resistant strains in the Klebsiella carbapenemase-producing group was higher (45% for the reference method and E-test and 40% for the Phoenix method) than in carbapenemase-negative strains (25%, 25%, and 20%, respectively). Full (100%) susceptibility categorical agreement was achieved for the E-test and the reference method. Agreement between the automated Phoenix system and the reference method reached 86%. Conclusions: Fosfomycin appears to be the antibiotic with a potential for use in the treatment of infections with multidrug-resistant Klebsiella strains. Susceptibility to this drug is exhibited by some strains, which are resistant to colistin and carbapenems. The E-test, unlike the Phoenix method, can be an alternative to the reference method in the routine determination of fosfomycin susceptibility, as it shows agreement in terms of sensitivity categories and only slight differences in MIC values. The Phoenix system, in comparison to the reference method, shows large discrepancies in the MIC values and in the susceptibility category. [ABSTRACT FROM AUTHOR]

Published
2021
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