5 results on '"P.G. Tipping"'
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2. Contents, Vol. 43, 1986
- Author
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Hiroshi Tsuruda, M. Granowska, T. Horne, Ursula Rother, Noriyuki Nawa, C.C. Nimmon, W. Bosaller, Jürgen Bommer, Keiko Yamamoto, Eishin Yaoita, Yasuhide Mizutani, M.M. Stevenson, A. Pauls, Fujio Shimizu, Wataru Mitsuoka, Masato Seki, A.W. Asscher, L. Verresen, Hiroyuki Ohi, Stefano Bombardieri, M.R. Lee, S.R. Holdsworth, J. Madrenas, L Moriconi, M.V. García-Lucena, Eberhard Ritz, Michinobu Hatano, J.A.B. Keogh, Giuseppe Gremignai, B. Gallimore, J.A. Rodríguez, Michael Kirschfink, S. Codina, Katsutoshi Kawasaki, J.B. Young, R. Hirschberg, K.-U. Eckardt, Pier Vittorio Fosella, H. Eckardt, M. E. De Broe, J. Saupe, R.L. Lins, Clodoveo Ferri, K.E. Britton, A.M. Brownjohn, Max Notohamiprodjo, Itaru Kihara, Kaoru Onoyama, G. Paleologo, D. von Herrath, E. Mlodkowska, W.A. De Backer, Nobuaki Ohchi, Jose Strauss, K. Schaefer, Konrad Andrassy, Gaston Zilleruelo, Fumio Nanishi, Masatoshi Fujishima, Chen H. Hsu, R.F. Gagnon, Allan Juhl, Theodore W. Kurtz, W. Höfer, Tetsuro Ikezawa, Paola Migliorini, E. Ferrer, M. Carroll, Shizuhiko Watanabe, P.G. Tipping, Kazuo Kobayashi, Yukinori Oh, M.K. Nawaz, Mj. Harber, E.F. Gaffney, L. Piera, Carolyn Abitbol, J. Monné, and Tadashi Yamamoto
- Subjects
Traditional medicine ,business.industry ,Medicine ,business - Published
- 1986
- Full Text
- View/download PDF
3. Effect of cyclosporin A on antibody-induced experimental glomerulonephritis
- Author
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S.R. Holdsworth and P.G. Tipping
- Subjects
Male ,medicine.medical_specialty ,Globulin ,Kidney Glomerulus ,Fluorescent Antibody Technique ,Cyclosporins ,urologic and male genital diseases ,medicine.disease_cause ,Kidney ,Antibodies ,Basement Membrane ,Autoimmunity ,Glomerulonephritis ,Internal medicine ,Cyclosporin a ,medicine ,Animals ,Basement membrane ,Proteinuria ,Sheep ,biology ,urogenital system ,business.industry ,Rats, Inbred Strains ,medicine.disease ,Ciclosporin ,female genital diseases and pregnancy complications ,Rats ,medicine.anatomical_structure ,Endocrinology ,biology.protein ,Antibody ,medicine.symptom ,business ,medicine.drug - Abstract
The effect of cyclosporin A (C YA) on the development of active and passive modeis of rat anti-glomerular basement membrane antibody-induced glomerulonephritis (anti-GBM-GN) was assessed. Active GN was induced by an intravenous injection of sheep anti-rat GBM globulin to preimmunized rats. After 5 days, a diffuse proliferative GN with proteinuria and linear GBM deposition of rat IgG was regularly observed. CYA treatment, commencing prior to preimmunization, significantly attenuated the glomerular lesion, reduced proteinuria, prevented linear deposition of rat IgG and reduced the serum titre of anti-sheep globulin antibody. However, treatment started after the antibody response was established failed to alter antibody production, its glomerular deposition or the outcome of the disease. CYA treatment did not effect passive anti-GBM-GN, occurring 24 h after intravenous administration of sheep anti-rat GBM globulin to unimmunized rats. Thus, CYA is able to block anti-GBM-GN when given prior to induction of disease, by preventing an active antibody response. However, it did not alter GN when the antibody response was well established, or when glomerular injury was passively induced.
- Published
- 1985
4. Fibrinolytic therapy with streptokinase for established experimental glomerulonephritis
- Author
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S.R. Holdsworth and P.G. Tipping
- Subjects
Pathology ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,Streptokinase ,Kidney ,Experimental glomerulonephritis ,Fibrin ,Glomerulonephritis ,medicine ,Animals ,Chemotherapy ,Lagomorpha ,biology ,business.industry ,Fibrinolysis ,Fibrinogen ,medicine.disease ,biology.organism_classification ,Basement membrane Antibody ,Immunology ,biology.protein ,Fibrinolytic therapy ,Rabbits ,business ,medicine.drug - Abstract
The efficacy of fibrinolytic therapy with streptokinase was assessed in rabbits developing anti-glomerular basement membrane antibody induced glomerulonephritis. Untreated animals developed renal failure (mean creatinine 615 +/- 120 microM/l) and a severe glomerulonephritis with prominent fibrin deposition. Streptokinase treatment of animals with established disease (creatinine 204 +/- 35 microM/l) reduced renal impairment (creatinine 256 +/- 68 microM/l, p less than 0.025) and fibrin deposition. Treatment of more advanced disease (creatinine 416 +/- 68 microM/l) did not preserve renal function (creatinine, 518 +/- 106 microM/l), although glomerular fibrin deposition was reduced. These studies indicate that fibrinolytic therapy with streptokinase reduces glomerular fibrin deposition and, if used early, protects from loss of renal function.
- Published
- 1986
5. Subject Index, Vol. 43, 1986
- Author
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Konrad Andrassy, P.G. Tipping, M.K. Nawaz, L Moriconi, A. Pauls, Kazuo Kobayashi, M. Granowska, Yukinori Oh, Fumio Nanishi, Tadashi Yamamoto, H. Eckardt, C.C. Nimmon, Allan Juhl, M.M. Stevenson, L. Verresen, D. von Herrath, Theodore W. Kurtz, Michinobu Hatano, Paola Migliorini, E. Ferrer, A.M. Brownjohn, Kaoru Onoyama, Shizuhiko Watanabe, M.R. Lee, R.F. Gagnon, K. Schaefer, Masato Seki, Itaru Kihara, R.L. Lins, Nobuaki Ohchi, L. Piera, W. Höfer, Carolyn Abitbol, Gaston Zilleruelo, Ursula Rother, J. Madrenas, Jose Strauss, J.B. Young, Yasuhide Mizutani, W. Bosaller, Tetsuro Ikezawa, Max Notohamiprodjo, J.A.B. Keogh, M. Carroll, Pier Vittorio Fosella, T. Horne, K.-U. Eckardt, Clodoveo Ferri, K.E. Britton, S.R. Holdsworth, Jürgen Bommer, Chen H. Hsu, Keiko Yamamoto, Stefano Bombardieri, Eishin Yaoita, Fujio Shimizu, Wataru Mitsuoka, Hiroshi Tsuruda, Eberhard Ritz, Noriyuki Nawa, Giuseppe Gremignai, J.A. Rodríguez, Michael Kirschfink, R. Hirschberg, M. E. De Broe, Masatoshi Fujishima, J. Saupe, W.A. De Backer, Hiroyuki Ohi, J. Monné, Katsutoshi Kawasaki, G. Paleologo, E. Mlodkowska, B. Gallimore, A.W. Asscher, M.V. García-Lucena, S. Codina, Mj. Harber, and E.F. Gaffney
- Subjects
Index (economics) ,business.industry ,Statistics ,Medicine ,Subject (documents) ,business - Published
- 1986
- Full Text
- View/download PDF
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