Search

Your search keyword '"P. Simmerling"' showing total 150 results
Start Over Author "P. Simmerling"
150 results on '"P. Simmerling"'

1. A multidimensional study of the structure function ratio σLT′/σ0 from hard exclusive π+ electro-production off protons in the GPD regime

Author

S. Diehl, A. Kim, K. Joo, P. Achenbach, Z. Akbar, M.J. Amaryan, H. Atac, H. Avagyan, C. Ayerbe Gayoso, L. Baashen, L. Barion, M. Bashkanov, M. Battaglieri, I. Bedlinskiy, B. Benkel, F. Benmokhtar, A. Bianconi, A.S. Biselli, M. Bondi, W.A. Booth, F. Bossù, S. Boiarinov, K.-Th. Brinkmann, W.J. Briscoe, S. Bueltmann, D. Bulumulla, V.D. Burkert, D.S. Carman, A. Celentano, P. Chatagnon, V. Chesnokov, T. Chetry, G. Ciullo, G. Clash, P.L. Cole, M. Contalbrigo, G. Costantini, A. D'Angelo, N. Dashyan, R. De Vita, M. Defurne, A. Deur, C. Djalali, R. Dupre, H. Egiyan, M. Ehrhart, A. El Alaoui, L. El Fassi, L. Elouadrhiri, S. Fegan, A. Filippi, G. Gavalian, Y. Ghandilyan, G.P. Gilfoyle, D.I. Glazier, A.A. Golubenko, G. Gosta, R.W. Gothe, Y. Gotra, K.A. Griffioen, M. Guidal, K. Hafidi, H. Hakobyan, M. Hattawy, T.B. Hayward, D. Heddle, A. Hobart, M. Holtrop, Y. Ilieva, D.G. Ireland, E.L. Isupov, H.S. Jo, M. Khachatryan, A. Khanal, W. Kim, A. Kripko, V. Kubarovsky, V. Lagerquist, J.-M. Laget, L. Lanza, M. Leali, S. Lee, P. Lenisa, X. Li, K. Livingston, I. .J .D. MacGregor, D. Marchand, V. Mascagna, B. McKinnon, Z.E. Meziani, S. Migliorati, T. Mineeva, M. Mirazita, V. Mokeev, E. Molina, R.A. Montgomery, C. Munoz Camacho, P. Nadel-Turonski, P. Naidoo, K. Neupane, S. Niccolai, M. Nicol, G. Niculescu, M. Osipenko, M. Ouillon, P. Pandey, M. Paolone, L.L. Pappalardo, R. Paremuzyan, E. Pasyuk, S.J. Paul, W. Phelps, N. Pilleux, M. Pokhrel, J. Poudel, J.W. Price, Y. Prok, T. Reed, J. Richards, M. Ripani, J. Ritman, P. Rossi, F. Sabatié, C. Salgado, S. Schadmand, A. Schmidt, Y. Sharabian, E.V. Shirokov, U. Shrestha, P. Simmerling, D. Sokhan, N. Sparveris, M. Spreafico, S. Stepanyan, I.I. Strakovsky, S. Strauch, J.A. Tan, N. Trotta, M. Turisini, R. Tyson, M. Ungaro, S. Vallarino, L. Venturelli, H. Voskanyan, E. Voutier, D.P. Watts, X. Wei, R. Williams, R. Wishart, M.H. Wood, N. Zachariou, J. Zhang, Z.W. Zhao, and M. Zurek

Subjects
Exclusive single pion, Eletroproduction, GPD, CLAS12, Physics, QC1-999
Abstract

A multidimensional extraction of the structure function ratio σLT′/σ0 from the hard exclusive e→p→e′nπ+ reaction above the resonance region has been performed. The study was done based on beam-spin asymmetry measurements using a 10.6 GeV incident electron beam on a liquid-hydrogen target and the CLAS12 spectrometer at Jefferson Lab. The measurements focus on the very forward regime (t/Q2 ≪ 1) with a wide kinematic range of xB in the valence regime (0.17 < xB < 0.55), and virtualities Q2 ranging from 1.5 GeV2 up to 6 GeV2. The results and their comparison to theoretical models based on Generalized Parton Distributions demonstrate the sensitivity to chiral-odd GPDs and the directly related tensor charge of the nucleon. In addition, the data is compared to an extension of a Regge formalism at high photon virtualities. It was found that the Regge model provides a better description at low Q2, while the GPD model is more appropriate at high Q2.

Published
2023
Full Text
View/download PDF

2. The need to implement FAIR principles in biomolecular simulations

Author

Amaro, Rommie, Åqvist, Johan, Bahar, Ivet, Battistini, Federica, Bellaiche, Adam, Beltran, Daniel, Biggin, Philip C., Bonomi, Massimiliano, Bowman, Gregory R., Bryce, Richard, Bussi, Giovanni, Carloni, Paolo, Case, David, Cavalli, Andrea, Chang, Chie-En A., Cheatham III, Thomas E., Cheung, Margaret S., Chipot, Cris, Chong, Lillian T., Choudhary, Preeti, Cisneros, Gerardo Andres, Clementi, Cecilia, Collepardo-Guevara, Rosana, Coveney, Peter, Covino, Roberto, Crawford, T. Daniel, Peraro, Matteo Dal, de Groot, Bert, Delemotte, Lucie, De Vivo, Marco, Essex, Jonathan, Fraternali, Franca, Gao, Jiali, Gelpí, Josep Lluís, Gervasio, Francesco Luigi, Gonzalez-Nilo, Fernando Danilo, Grubmüller, Helmut, Guenza, Marina, Guzman, Horacio V., Harris, Sarah, Head-Gordon, Teresa, Hernandez, Rigoberto, Hospital, Adam, Huang, Niu, Huang, Xuhui, Hummer, Gerhard, Iglesias-Fernández, Javier, Jensen, Jan H., Jha, Shantenu, Jiao, Wanting, Jorgensen, William L., Kamerlin, Shina Caroline Lynn, Khalid, Syma, Laughton, Charles, Levitt, Michael, Limongelli, Vittorio, Lindahl, Erik, Lindorff-Larsen, Kresten, Loverde, Sharon, Lundborg, Magnus, Luo, Yun Lyna, Luque, Francisco Javier, Lynch, Charlotte I., MacKerell, Alexander, Magistrato, Alessandra, Marrink, Siewert J., Martin, Hugh, McCammon, J. Andrew, Merz, Kenneth, Moliner, Vicent, Mulholland, Adrian, Murad, Sohail, Naganathan, Athi N., Nangia, Shikha, Noe, Frank, Noy, Agnes, Oláh, Julianna, O'Mara, Megan, Ondrechen, Mary Jo, Onuchic, José N., Onufriev, Alexey, Osuna, Silvia, Panchenko, Anna R., Pantano, Sergio, Parish, Carol, Parrinello, Michele, Perez, Alberto, Perez-Acle, Tomas, Perilla, Juan R., Pettitt, B. Montgomery, Pietropalo, Adriana, Piquemal, Jean-Philip, Poma, Adolfo, Praprotnik, Matej, Ramos, Maria J., Ren, Pengyu, Reuter, Nathalie, Roitberg, Adrian, Rosta, Edina, Rovira, Carme, Roux, Benoit, Röthlisberger, Ursula, Sanbonmatsu, Karissa Y., Schlick, Tamar, Shaytan, Alexey K., Simmerling, Carlos, Smith, Jeremy C., Sugita, Yuji, Świderek, Katarzyna, Taiji, Makoto, Tao, Peng, Tikhonova, Irina G., Tirado-Rives, Julian, Tunón, Inaki, Van Der Kamp, Marc W., Van der Spoel, David, Velankar, Sameer, Voth, Gregory A., Wade, Rebecca, Warshel, Ariel, Welborn, Valerie Vaissier, Wetmore, Stacey, Wong, Chung F., Yang, Lee-Wei, Zacharias, Martin, and Orozco, Modesto

Subjects
Quantitative Biology - Biomolecules
Abstract

This letter illustrates the opinion of the molecular dynamics (MD) community on the need to adopt a new FAIR paradigm for the use of molecular simulations. It highlights the necessity of a collaborative effort to create, establish, and sustain a database that allows findability, accessibility, interoperability, and reusability of molecular dynamics simulation data. Such a development would democratize the field and significantly improve the impact of MD simulations on life science research. This will transform our working paradigm, pushing the field to a new frontier. We invite you to support our initiative at the MDDB community (https://mddbr.eu/community/)

Published
2024

3. Exact analytical algorithm for solvent accessible surface area and derivatives in implicit solvent molecular simulations on GPUs

Author

Cao, Xin, Hummel, Michelle H., Wang, Yuzhang, Simmerling, Carlos, and Coutsias, Evangelos A.

Subjects
Quantitative Biology - Biomolecules
Abstract

In this paper, we present dSASA (differentiable SASA), an exact geometric method to calculate solvent accessible surface area (SASA) analytically along with atomic derivatives on GPUs. The atoms in a molecule are first assigned to tetrahedra in groups of four atoms by Delaunay tetrahedrization adapted for efficient GPU implementation and the SASA values for atoms and molecules are calculated based on the tetrahedrization information and inclusion-exclusion method. The SASA values from the numerical icosahedral-based method can be reproduced with more than 98% accuracy for both proteins and RNAs. Having been implemented on GPUs and incorporated into the software Amber, we can apply dSASA to implicit solvent molecular dynamics simulations with inclusion of this nonpolar term. The current GPU version of GB/SA simulations has been accelerated up to nearly 20-fold compared to the CPU version, outperforming LCPO, a commonly used, fast algorithm for calculating SASA, as the system size increases. While we focus on the accuracy of the SASA calculations for proteins and nucleic acids, we also demonstrate stable GB/SA MD mini-protein simulations.

Published
2024

4. AmberTools

Author

Case, David A, Aktulga, Hasan Metin, Belfon, Kellon, Cerutti, David S, Cisneros, G Andrés, Cruzeiro, Vinícius Wilian D, Forouzesh, Negin, Giese, Timothy J, Götz, Andreas W, Gohlke, Holger, Izadi, Saeed, Kasavajhala, Koushik, Kaymak, Mehmet C, King, Edward, Kurtzman, Tom, Lee, Tai-Sung, Li, Pengfei, Liu, Jian, Luchko, Tyler, Luo, Ray, Manathunga, Madushanka, Machado, Matias R, Nguyen, Hai Minh, O’Hearn, Kurt A, Onufriev, Alexey V, Pan, Feng, Pantano, Sergio, Qi, Ruxi, Rahnamoun, Ali, Risheh, Ali, Schott-Verdugo, Stephan, Shajan, Akhil, Swails, Jason, Wang, Junmei, Wei, Haixin, Wu, Xiongwu, Wu, Yongxian, Zhang, Shi, Zhao, Shiji, Zhu, Qiang, Cheatham, Thomas E, Roe, Daniel R, Roitberg, Adrian, Simmerling, Carlos, York, Darrin M, Nagan, Maria C, and Merz, Kenneth M

Subjects
Medicinal and Biomolecular Chemistry, Chemical Sciences, Theoretical and Computational Chemistry, Computation Theory and Mathematics, Medicinal & Biomolecular Chemistry, Medicinal and biomolecular chemistry, Theoretical and computational chemistry
Abstract

AmberTools is a free and open-source collection of programs used to set up, run, and analyze molecular simulations. The newer features contained within AmberTools23 are briefly described in this Application note.

Published
2023

5. First CLAS12 measurement of DVCS beam-spin asymmetries in the extended valence region

Author

CLAS Collaboration, Christiaens, G., Defurne, M., Sokhan, D., Achenbach, P., Akbar, Z., Amaryan, M. J., Atac, H., Avakian, H., Gayoso, C. Ayerbe, Baashen, L., Baltzell, N. A., Barion, L., Bashkanov, M., Battaglieri, M., Bedlinskiy, I., Benkel, B., Benmokhtar, F., Bianconi, A., Biselli, A. S., Bondi, M., Booth, W. A., Bossù, F., Boiarinov, S., Brinkmann, K. -Th., Briscoe, W. J., Bueltmann, S., Bulumulla, D., Burkert, V. D., Cao, T., Carman, D. S., Carvajal, J. C., Celentano, A., Chatagnon, P., Chesnokov, V., Chetry, T., Ciullo, G., Clash, G., Cole, P. L., Contalbrigo, M., Costantini, G., D'Angelo, A., Dashyan, N., De Vita, R., Deur, A., Diehl, S., Dilks, C., Djalali, C., Dupre, R., Egiyan, H., Ehrhart, M., Alaoui, A. El, Fassi, L. El, Elouadrhiri, L., Fegan, S., Filippi, A., Gates, K., Gavalian, G., Ghandilyan, Y., Gilfoyle, G. P., Girod, F. X., Glazier, D. I., Golubenko, A. A., Gosta, G., Gothe, R. W., Gotra, Y., Griffioen, K. A., Guidal, M., Hafidi, K., Hakobyan, H., Hattawy, M., Hauenstein, F., Hayward, T. B., Heddle, D., Hobart, A., Holmberg, D. E., Holtrop, M., Ilieva, Y., Ireland, D. G., Isupov, E. L., Jo, H. S., Kabir, M. L., Keller, D., Khachatryan, M., Khanal, A., Kim, W., Kripko, A., Kubarovsky, V., Kuhn, S. E., Lagerquist, V., Lanza, L., Leali, M., Lee, S., Lenisa, P., Li, X., Livingston, K., MacGregor, I . J . D., Marchand, D., Mascagna, V., Matousek, G., McKinnon, B., McLauchlin, C., Meziani, Z. E., Migliorati, S., Milner, R. G., Mineeva, T., Mirazita, M., Mokeev, V., Molina, E., Camacho, C. Munoz, Nadel-Turonski, P., Naidoo, P., Neupane, K., Niccolai, S., Nicol, M., Niculescu, G., Osipenko, M., Ouillon, M., Pandey, P., Paolone, M., Pappalardo, L. L., Paremuzyan, R., Pasyuk, E., Paul, S. J., Phelps, W., Pilleux, N., Pokhrel, M., Poudel, J., Price, J. W., Prok, Y., Radic, A., Ramasubramanian, N., Raue, B. A., Reed, T., Richards, J., Ripani, M., Ritman, J., Rossi, P., Sabatié, F., Salgado, C., Schadmand, S., Schmidt, A., Scott, M. B. C., Sharabian, Y. G., Shirokov, E. V., Shrestha, U., Simmerling, P., Sparveris, N., Spreafico, M., Stepanyan, S., Strakovsky, I. I., Strauch, S., Tan, J. A., Trotta, N., Turisini, M., Tyson, R., Ungaro, M., Vallarino, S., Venturelli, L., Voskanyan, H., Voutier, E., Watts, D. P., Wei, X., Williams, R., Wishart, R., Wood, M. H., Zachariou, N., Zhang, J., Zhao, Z. W., Ziegler, V., and Zurek, M.

Subjects
High Energy Physics - Experiment
Abstract

Deeply virtual Compton scattering (DVCS) allows one to probe Generalized Parton Distributions (GPDs) describing the 3D structure of the nucleon. We report the first measurement of the DVCS beam-spin asymmetry using the CLAS12 spectrometer with a 10.2 and 10.6 GeV electron beam scattering from unpolarised protons. The results greatly extend the $Q^2$ and Bjorken-$x$ phase space beyond the existing data in the valence region and provide over 2000 new data points measured with unprecedented statistical uncertainty, setting new, tight constraints for future phenomenological studies., Comment: Revised Figure 4 and discussion around the number of effective ANNs after Bayesian reweighting

Published
2022

6. A multidimensional study of the structure function ratio $\sigma_{LT'}/\sigma_{0}$ from hard exclusive $\pi^+$ electro-production off protons in the GPD regime

Author

Diehl, S., Kim, A., Joo, K., Achenbach, P., Akbar, Z., Amaryan, M. J., Atac, H., Avagyan, H., Gayoso, C. Ayerbe, Baashen, L., Barion, L., Bashkanov, M., Battaglieri, M., Bedlinskiy, I., Benkel, B., Benmokhtar, F., Bianconi, A., Biselli, A. S., Bondi, M., Booth, W. A., Bossu, F., Boiarinov, S., Brinkmann, K. -Th., Briscoe, W. J., Bueltmann, S., Bulumulla, D., Burkert, V. D., Carman, D. S., Celentano, A., Chatagnon, P., Chesnokov, V., Chetry, T., Ciullo, G., Clash, G., Cole, P. L., Contalbrigo, M., Costantini, G., D'Angelo, A., Dashyan, N., De Vita, R., Defurne, M., Deur, A., Djalali, C., Dupre, R., Egiyan, H., Ehrhart, M., Alaoui, A. El, Fassi, L. El, Elouadrhiri, L., Fegan, S., Filippi, A., Gavalian, G., Ghandilyan, Y., Gilfoyle, G. P., Glazier, D. I., Golubenko, A. A., Gosta, G., Gothe, R. W., Gotra, Y., Grifoen, K. A., Guidal, M., Hafdi, K., Hakobyan, H., Hattawy, M., Hayward, T. B., Heddle, D., Hobart, A., Holtrop, M., Ilieva, Y., Ireland, D. G., Isupov, E. L., Jo, H. S., Khachatryan, M., Khanal, A., Kim, W., Kripko, A., Kubarovsky, V., Lagerquist, V., Laget, J. -M., Lanza, L., Leali, M., Lee, S., Lenisa, P., Li, X., Livingston, K., MacGregor, I . J. D., Marchand, D., Mascagna, V., McKinnon, B., Meziani, Z. E., Migliorati, S., Mineeva, T., Mirazita, M., Mokeev, V., Molina, Esteban, Montgomery, R. A., Camacho, C. Munoz, Nadel-Turonski, P., Naidoo, P., Neupane, K., Niccolai, S., Nicol, M., Niculescu, G., Osipenko, M., Ouillon, M., Pandey, P., Paolone, M., Pappalardo, L. L., Paremuzyan, R., Pasyuk, E., Paul, S. J., Phelps, W., Pilleux, N., Pokhrel, M., Poudel, J., Price, J. W., Prok, Y., Reed, Trevor, Richards, J., Ripani, M., Ritman, J., Rossi, P., Sabatie, F., Salgado, C., Schadmand, S., Schmidt, A., Sharabian, Y., Shirokov, E. V., Shrestha, U., Simmerling, P., Sokhan, D., Sparveris, N., Spreafco, M., Stepanyan, S., Strakovsky, I. I., Strauch, S., Tan, J. A., Trotta, N., Turisini, M., Tyson, R., Ungaro, M., Vallarino, S., Venturelli, L., Voskanyan, H., Voutier, E., Watts, D. P., Wei, X., Williams, R., Wishart, R., Wood, M. H., Zachariou, N., Zhang, J., Zhao, Z. W., and Zurek, M.

Subjects
High Energy Physics - Experiment
Abstract

A multidimensional extraction of the structure function ratio $\sigma_{LT'}/\sigma_{0}$ from the hard exclusive $\vec{e} p \to e^\prime n \pi^+$ reaction above the resonance region has been performed. The study was done based on beam-spin asymmetry measurements using a 10.6 GeV incident electron beam on a liquid-hydrogen target and the CLAS12 spectrometer at Jefferson Lab. The measurements focus on the very forward regime ($t/Q^{2}$ $\ll$ 1) with a wide kinematic range of $x_{B}$ in the valence regime (0.17 $<$ $x_{B}$ $<$ 0.55), and virtualities $Q^{2}$ ranging from 1.5 GeV$^{2}$ up to 6 GeV$^{2}$. The results and their comparison to theoretical models based on Generalized Parton Distributions demonstrate the sensitivity to chiral-odd GPDs and the directly related tensor charge of the nucleon. In addition, the data is compared to an extension of a Regge formalism at high photon virtualities. It was found that the Regge model provides a better description at low $Q^{2}$, while the GPD model is more appropriate at high $Q^{2}$., Comment: arXiv admin note: text overlap with arXiv:2007.15677

Published
2022
Full Text
View/download PDF

7. First Measurement of $\Lambda$ Electroproduction off Nuclei in the Current and Target Fragmentation Regions

Author

Chetry, T., Fassi, L. El, Brooks, W. K., Dupré, R., Alaoui, A. El, Hafidi, K., Achenbach, P., Adhikari, K. P., Akbar, Z., Armstrong, W. R., Arratia, M., Atac, H., Avakian, H., Baashen, L., Baltzell, N. A., Barion, L., Bashkanov, M., Battaglieri, M., Bedlinskiy, I., Benkel, B., Benmokhtar, F., Bianconi, A., Biselli, A. S., Bondi, M., Booth, W. A., Bossù, F., Boiarinov, S., Brinkmann, K. -Th., Briscoe, W. J., Bulumulla, D., Burkert, V. D., Carman, D. S., Carvajal, J. C., Celentano, A., Chatagnon, P., Chesnokov, V., Ciullo, G., Cole, P. L., Contalbrigo, M., Costantini, G., D'Angelo, A., Dashyan, N., De Vita, R., Defurne, M., Deur, A., Diehl, S., Djalali, C., Egiyan, H., Elouadrhiri, L., Eugenio, P., Fegan, S., Filippi, A., Gavalian, G., Ghandilyan, Y., Gilfoyle, G. P., Glazier, D. I., Golubenko, A. A., Gosta, G., Gothe, R. W., Griffioen, K. A., Guidal, M., Guo, L., Hakobyan, H., Hattawy, M., Hayward, T. B., Heddle, D., Hobart, A., Holtrop, M., Ilieva, Y., Ireland, D. G., Isupov, E. L., Jenkins, D., Jo, H. S., Kabir, M. L., Khanal, A., Khandaker, M., Kim, A., Kim, W., Klein, F. J., Kripko, A., Kubarovsky, V., Lagerquist, V., Lanza, L., Leali, M., Lee, S., Lenisa, P., Li, X., Livingston, K., MacGregor, I. J. D., Marchand, D., Mascagna, V., McKinnon, B., McLauchlin, C., Meziani, Z. E., Migliorati, S., Mineeva, T., Mirazita, M., Mokeev, V., Camacho, C. Munoz, Nadel-Turonski, P., Neupane, K., Niccolai, S., Nicol, M., Niculescu, G., Osipenko, M., Ostrovidov, A. I., Pandey, P., Paolone, M., Pappalardo, L. L., Paremuzyan, R., Pasyuk, E., Paul, S. J., Phelps, W., Pilleux, N., Pokhrel, M., Poudel, J., Price, J. W., Prok, Y., Raue, B. A., Reed, T., Richards, J., Ripani, M., Ritman, J., Rosner, G., Sabatié, F., Salgado, C., Schadmand, S., Schmidt, A., Schumacher, R. A., Sharabian, Y. G., Shirokov, E. V., Shrestha, U., Simmerling, P., Sokhan, D., Sparveris, N., Stepanyan, S., Strakovsky, I. I., Strauch, S., Tan, J. A., Trotta, N., Tyson, R., Ungaro, M., Vallarino, S., Venturelli, L., Voskanyan, H., Voutier, E., Wei, X., Weinstein, L. B., Williams, R., Wishart, R., Wood, M. H., Zachariou, N., Zhao, Z. W., and Zurek, M.

Subjects
Nuclear Experiment, High Energy Physics - Experiment
Abstract

We report results of $\Lambda$ hyperon production in semi-inclusive deep-inelastic scattering off deuterium, carbon, iron, and lead targets obtained with the CLAS detector and the Continuous Electron Beam Accelerator Facility 5.014~GeV electron beam. These results represent the first measurements of the $\Lambda$ multiplicity ratio and transverse momentum broadening as a function of the energy fraction~($z$) in the current and target fragmentation regions. The multiplicity ratio exhibits a strong suppression at high~$z$~and~an enhancement at~low~$z$. The measured transverse momentum broadening is an order of magnitude greater than that seen for light mesons. This indicates that the propagating entity interacts very strongly with the nuclear medium, which suggests that propagation of diquark configurations in the nuclear medium takes place at least part of the time, even at high~$z$. The trends of these results are qualitatively described by the Giessen Boltzmann-Uehling-Uhlenbeck transport model, particularly for the multiplicity ratios. These observations will potentially open a new era of studies of the structure of the nucleon as well as of strange baryons., Comment: 14 pages, 6 figures

Published
2022
Full Text
View/download PDF

8. Design of the ECCE Detector for the Electron Ion Collider

Author

Adkins, J. K., Akiba, Y., Albataineh, A., Amaryan, M., Arsene, I. C., Gayoso, C. Ayerbe, Bae, J., Bai, X., Baker, M. D., Bashkanov, M., Bellwied, R., Benmokhtar, F., Berdnikov, V., Bernauer, J. C., Bock, F., Boeglin, W., Borysova, M., Brash, E., Brindza, P., Briscoe, W. J., Brooks, M., Bueltmann, S., Bukhari, M. H. S., Bylinkin, A., Capobianco, R., Chang, W. -C., Cheon, Y., Chen, K., Chen, K. -F., Cheng, K. -Y., Chiu, M., Chujo, T., Citron, Z., Cline, E., Cohen, E., Conroy, E., Cormier, T., Morales, Y. Corrales, Cotton, C., Crafts, J., Crawford, C., Creekmore, S., Cuevas, C., Cunningham, J., David, G., Dean, C. T., Demarteau, M., Diehl, S., Doshita, N., Dupré, R., Durham, J. M., Dzhygadlo, R., Ehlers, R., Fassi, L. El, Emmert, A., Ent, R., Fanelli, C., Fatemi, R., Fegan, S., Finger, M., Finger Jr., M., Frantz, J., Friedman, M., Friscic, I., Gangadharan, D., Gardner, S., Gates, K., Geurts, F., Gilman, R., Glazier, D., Glimos, E., Goto, Y., Grau, N., Greene, S. V., Guo, A. Q., Guo, L., Gwenian, C., Ha, S. K., Haggerty, J., Hayward, T., He, X., Hen, O., Higinbotham, D. W., Hoballah, M., Horn, T., Hoghmrtsyan, A., Hsu, P. -h. J., Huang, J., Huber, G., Hutson, A., Hwang, K. Y., Hyde, C. E., Inaba, M., Iwata, T., Jo, H. S., Joo, K., Kalantarians, N., Kalicy, G., Kawade, K., Kay, S. J. D., Kim, A., Kim, B., Kim, C., Kim, M., Kim, Y., Kistenev, E., Klimenko, V., Ko, S. H., Korover, I., Korsch, W., Krintiras, G., Kuhn, S., Kuo, C. -M., Kutz, T., Lajoie, J., Lawrence, D., Lebedev, S., Lee, H., Lee, J. S. H., Lee, S. W., Lee, Y. -J., Li, W., Li, X., Liang, Y. T., Lim, S., Lin, C. -H., Lin, D. X., Liu, K., Liu, M. X., Livingston, K., Liyanage, N., Llope, W. J., Loizides, C., Long, E., Lu, R. -S., Lu, Z., Lynch, W., Marchand, D., Marcisovsky, M., Markert, C., Markowitz, P., Marukyan, H., McGaughey, P., Mihovilovic, M., Milner, R. G., Milov, A., Miyachi, Y., Mkrtchyan, A., Monaghan, P., Montgomery, R., Morrison, D., Movsisyan, A., Mkrtchyan, H., Camacho, C. Munoz, Murray, M., Nagai, K., Nagle, J., Nakagawa, I., Nattrass, C., Nguyen, D., Niccolai, S., Nouicer, R., Nukazuka, G., Nycz, M., Okorokov, V. A., Orešić, S., Osborn, J. D., O'Shaughnessy, C., Paganis, S., Papandreou, Z, Pate, S. F., Patel, M., Paus, C., Penman, G., Perdekamp, M. G., Perepelitsa, D. V., da Costa, H. Periera, Peters, K., Phelps, W., Piasetzky, E., Pinkenburg, C., Prochazka, I., Protzman, T., Purschke, M. L., Putschke, J., Pybus, J. R., Rajput-Ghoshal, R., Rasson, J., Raue, B., Read, K., Røed, K., Reed, R., Reinhold, J., Renner, E. L., Richards, J., Riedl, C., Rinn, T., Roche, J., Roland, G. M., Ron, G., Rosati, M., Royon, C., Ryu, J., Salur, S., Santiesteban, N., Santos, R., Sarsour, M., Schambach, J., Schmidt, A., Schmidt, N., Schwarz, C., Schwiening, J., Seidl, R., Sickles, A., Simmerling, P., Sirca, S., Sharma, D., Shi, Z., Shibata, T. -A., Shih, C. -W., Shimizu, S., Shrestha, U., Slifer, K., Smith, K., Sokhan, D., Soltz, R., Sondheim, W., Song, J., Strakovsky, I. I., Steinberg, P., Stepanov, P., Stevens, J., Strube, J., Sun, P., Sun, X., Suresh, K., Tadevosyan, V., Tang, W. -C., Araya, S. Tapia, Tarafdar, S., Teodorescu, L., Thomas, D., Timmins, A., Tomasek, L., Trotta, N., Trotta, R., Tveter, T. S., Umaka, E., Usman, A., van Hecke, H. W., Van Hulse, C., Velkovska, J., Voutier, E., Wang, P. K., Wang, Q., Wang, Y., Watts, D. P., Wickramaarachchi, N., Weinstein, L., Williams, M., Wong, C. -P., Wood, L., Wood, M. H., Woody, C., Wyslouch, B., Xiao, Z., Yamazaki, Y., Yang, Y., Ye, Z., Yoo, H. D., Yurov, M., Zachariou, N., Zajc, W. A., Zhang, J., Zhang, Y., Zhao, Y. X., Zheng, X., and Zhuang, P.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

The EIC Comprehensive Chromodynamics Experiment (ECCE) detector has been designed to address the full scope of the proposed Electron Ion Collider (EIC) physics program as presented by the National Academy of Science and provide a deeper understanding of the quark-gluon structure of matter. To accomplish this, the ECCE detector offers nearly acceptance and energy coverage along with excellent tracking and particle identification. The ECCE detector was designed to be built within the budget envelope set out by the EIC project while simultaneously managing cost and schedule risks. This detector concept has been selected to be the basis for the EIC project detector., Comment: 34 pages, 30 figures, 9 tables

Published
2022

9. CORE -- a COmpact detectoR for the EIC

Author

CORE Collaboration, Alarcon, R., Baker, M., Baturin, V., Brindza, P., Bueltmann, S., Bukhari, M., Capobianco, R., Christy, E., Diehl, S., Dugger, M., Dupré, R., Dzhygadlo, R., Flood, K., Gnanvo, K., Guo, L., Hayward, T., Hattawy, M., Hoballah, M., Hohlmann, M., Hyde, C. E., Ilieva, Y., Jacobs, W. W., Joo, K., Kalicy, G., Kim, A., Kubarovsky, V., Lehmann, A., Li, W., Marchand, D., Marukyan, H., Murray, M. J., Montgomery, H. E., Morozov, V., Mostafanezhad, I., Movsisyan, A., Munevar, E., Camacho, C. Muñoz, Nadel-Turonski, P., Niccolai, S., Peters, K., Prokudin, A., Richards, J., Ritchie, B. G., Shrestha, U., Schmookler, B., Schnell, G., Schwarz, C., Schwiening, J., Schweitzer, P., Simmerling, P., Szumila-Vance, H., Tripathi, S., Trotta, N., Varner, G., Vossen, A., Voutier, E., Wickramaarachchi, N., and Zachariou, N.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

The COmpact detectoR for the Eic (CORE) Proposal was submitted to the EIC "Call for Collaboration Proposals for Detectors". CORE comprehensively covers the physics scope of the EIC Community White Paper and the National Academies of Science 2018 report. The design exploits advances in detector precision and granularity to minimize size. The central detector includes a 3Tesla, 2.5m solenoid. Tracking is primarily silicon. Electromagnetic calorimetry is based on the high performance crystals. Ring-imaging Cherenkov detectors provide hadronic particle identification., Comment: Contact authors: C.E. Hyde, chyde@odu.edu and P. Nadel-Turonski, turonski@jlab.org

Published
2022

10. Detector Requirements and Simulation Results for the EIC Exclusive, Diffractive and Tagging Physics Program using the ECCE Detector Concept

Author

Bylinkin, A., Dean, C. T., Fegan, S., Gangadharan, D., Gates, K., Kay, S. J. D., Korover, I., Li, W. B., Li, X., Montgomery, R., Nguyen, D., Penman, G., Pybus, J. R., Santiesteban, N., Trotta, R., Usman, A., Baker, M. D., Frantz, J., Glazier, D. I., Higinbotham, D. W., Horn, T., Huang, J., Huber, G., Reed, R., Roche, J., Schmidt, A., Steinberg, P., Stevens, J., Goto, Y., Camacho, C. Munoz, Murray, M., Papandreou, Z., Zha, W., Adkins, J. K., Akiba, Y., Albataineh, A., Amaryan, M., Arsene, I. C., Gayoso, C. Ayerbe, Bae, J., Bai, X., Bashkanov, M., Bellwied, R., Benmokhtar, F., Berdnikov, V., Bernauer, J. C., Bock, F., Boeglin, W., Borysova, M., Brash, E., Brindza, P., Briscoe, W. J., Brooks, M., Bueltmann, S., Bukhari, M. H. S., Capobianco, R., Chang, W. -C., Cheon, Y., Chen, K., Chen, K. -F., Cheng, K. -Y., Chiu, M., Chujo, T., Citron, Z., Cline, E., Cohen, E., Cormier, T., Morales, Y. Corrales, Cotton, C., Crafts, J., Crawford, C., Creekmore, S., Cuevas, C., Cunningham, J., David, G., Demarteau, M., Diehl, S., Doshita, N., Dupre, R., Durham, J. M., Dzhygadlo, R., Ehlers, R., Fassi, L. El, Emmert, A., Ent, R., Fanelli, C., Fatemi, R., Finger, M., Finger Jr., M., Friedman, M., Friscic, I., Gardner, S., Geurts, F., Gilman, R., Glimos, E., Grau, N., Greene, S. V., Guo, A. Q., Guo, L., Ha, S. K., Haggerty, J., Hayward, T., He, X., Hen, O., Hoballah, M., Hoghmrtsyan, A., Hsu, P. -h. J., Hutson, A., Hwang, K. Y., Hyde, C. E., Inaba, M., Iwata, T., Jo, H. S., Joo, K., Kalantarians, N., Kalicy, G., Kawade, K., Kim, A., Kim, B., Kim, C., Kim, M., Kim, Y., Kistenev, E., Klimenko, V., Ko, S. H., Korsch, W., Krintiras, G., Kuhn, S., Kuo, C. -M., Kutz, T., Lajoie, J., Lawrence, D., Lebedev, S., Lee, H., Lee, J. S. H., Lee, S. W., Lee, Y. -J., Li, W., Liang, Y. T., Lim, S., Lin, C. -h., Lin, D. X., Liu, K., Liu, M. X., Livingston, K., Liyanage, N., Llope, W. J., Loizides, C., Long, E., Lu, R. -S., Lu, Z., Lynch, W., Mantry, S., Marchand, D., Marcisovsky, M., Markert, C., Markowitz, P., Marukyan, H., McGaughey, P., Mihovilovic, M., Milner, R. G., Milov, A., Miyachi, Y., Mkrtchyan, A., Monaghan, P., Morrison, D., Movsisyan, A., Mkrtchyan, H., Nagai, K., Nagle, J., Nakagawa, I., Nattrass, C., Niccolai, S., Nouicer, R., Nukazuka, G., Nycz, M., Okorokov, V. A., Oresic, S., Osborn, J. D., O'Shaughnessy, C., Paganis, S., Pate, S. F., Patel, M., Paus, C., Perdekamp, M. G., Perepelitsa, D. V., da Costa, H. Periera, Peters, K., Phelps, W., Piasetzky, E., Pinkenburg, C., Prochazka, I., Protzman, T., Purschke, M. L., Putschke, J., Rajput-Ghoshal, R., Rasson, J., Raue, B., Read, K. F., Roed, K., Reinhold, J., Renner, E. L., Richards, J., Riedl, C., Rinn, T., Roland, G. M., Ron, G., Rosati, M., Royon, C., Ryu, J., Salur, S., Santos, R., Sarsour, M., Schambach, J., Schmidt, N., Schwarz, C., Schwiening, J., Seidl, R., Sickles, A., Simmerling, P., Sirca, S., Sharma, D., Shi, Z., Shibata, T. -A., Shih, C. -W., Shimizu, S., Shrestha, U., Slifer, K., Smith, K., Sokhan, D., Soltz, R., Sondheim, W., Song, J., Strakovsky, I. I., Stepanov, P., Strube, J., Sun, P., Sun, X., Suresh, K., Tadevosyan, V., Tang, W. -C., Araya, S. Tapia, Tarafdar, S., Teodorescu, L., Thomas, D., Timmins, A., Tomasek, L., Trotta, N., Tveter, T. S., Umaka, E., van Hecke, H. W., Van Hulse, C., Velkovska, J., Voutier, E., Wang, P. K., Wang, Q., Wang, Y., Watts, D. P., Wickramaarachchi, N., Weinstein, L., Williams, M., Wong, C. -P., Wood, L., Wood, M. H., Woody, C., Wyslouch, B., Xiao, Z., Yamazaki, Y., Yang, Y., Ye, Z., Yoo, H. D., Yurov, M., Zachariou, N., Zajc, W. A., Zhang, J. -L., and Zhang, J. -X.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

This article presents a collection of simulation studies using the ECCE detector concept in the context of the EIC's exclusive, diffractive, and tagging physics program, which aims to further explore the rich quark-gluon structure of nucleons and nuclei. To successfully execute the program, ECCE proposed to utilize the detecter system close to the beamline to ensure exclusivity and tag ion beam/fragments for a particular reaction of interest. Preliminary studies confirmed the proposed technology and design satisfy the requirements. The projected physics impact results are based on the projected detector performance from the simulation at 10 or 100 fb^-1 of integrated luminosity. Additionally, a few insights on the potential 2nd Interaction Region can (IR) were also documented which could serve as a guidepost for the future development of a second EIC detector.

Published
2022
Full Text
View/download PDF

11. First observation of correlations between spin and transverse momenta in back-to-back dihadron production at CLAS12

Author

Avakian, H., Hayward, T. B., Kotzinian, A., Armstrong, W. R., Atac, H., Gayoso, C. Ayerbe, Baashen, L., Baltzell, N. A., Barion, L., Bashkanov, M., Battaglieri, M., Bedlinskiy, I., Benmokhtar, F., Bianconi, A., Biondo, L., Biselli, A. S., Bondi, M., Boiarinov, S., Bossù, F., Brinkman, K. T., Briscoe, W. J., Brooks, W. K., Bueltmann, S., Bulumulla, D., Burkert, V. D., Capobianco, R., Carman, D. S., Carvajal, J. C., Celentano, A., Chatagnon, P., Chesnokov, V., Chetry, T., Ciullo, G., Cole, P. L., Contalbrigo, M., Costantini, G., D'Angelo, A., Dashyan, N., De Vita, R., Defurne, M., Deur, A., Diehl, S., Dilks, C., Djalali, C., Dupre, R., Egiyan, H., Alaoui, A. El, Fassi, L. El, Elouadrhiri, L., Fegan, S., Filippi, A., Forest, T., Gates, K., Gavalian, G., Gilyan, Y., Glazier, D. I., Golubenko, A. A., Gosta, G., Gothe, R. W., Gotra, Y., Griffioen, K. A., Guidal, M., Hakobyan, H., Hattawy, M., Hauenstein, F., Heddle, D., Hobart, A., Holtrop, M., Hyde, C. E., Ilieva, Y., Ire, D. G., Isupov, E. L., Jo, H. S., Johnston, R., Joo, K., Kabir, M. L., Keller, D., Khachatryan, M., Khanal, A., Kim, A., Kim, W., Klimenko, V., Kripko, A., Kubarovsky, V., Kuhn, S. E., Lagerquist, V., Lanza, L., Leali, M., Lee, S., Lenisa, P., Li, X., MacGregor, I . J . D., Marc, D., Mascagna, V., McKinnon, B., Migliorati, S., Mineeva, T., Mirazita, M., Mokeev, V., Montgomery, R. A., Camacho, C. Munoz, Nadel-Turonski, P., Naidoo, P., Neupane, K., Nguyen, D., Niccolai, S., Nicol, M., Niculescu, G., Osipenko, M., Pandey, P., Paolone, M., Pappalardo, L. L., Paremuzyan, R., Pasyuk, E., Paul, S. J., Phelps, W., Pilleux, N., Pogorelko, O., Pokhrel, M., Poudel, J., Price, J. W., Prok, Y., Raue, B. A., Reed, T., Richards, J., Ripani, M., Ritman, J., Rossi, P., Sabatié, F., Salgado, C., Schmidt, A., Sharabian, Y. G., Shirokov, E. V., Shrestha, U., Simmerling, P., Sokhan, D., Sparveris, N., Stepanyan, S., Strakovsky, I. I., Strauch, S., Tan, J. A., Trotta, N., Tyson, R., Ungaro, M., Vallarino, S., Venturelli, L., Voskanyan, H., Vossen, A., Voutier, E., Watts, D. P., Wei, X., Wishart, R., Wood, M. H., Zachariou, N., Zhao, Z. W., and Zurek, M.

Subjects
High Energy Physics - Experiment, Nuclear Experiment
Abstract

We report the first measurements of deep inelastic scattering spin-dependent azimuthal asymmetries in back-to-back dihadron electroproduction, where two hadrons are produced in opposite hemispheres along the z-axis in the center-of-mass frame, with the first hadron produced in the current-fragmentation region and the second in the target-fragmentation region. The data were taken with longitudinally polarized electron beams of 10.2 and 10.6 GeV incident on an unpolarized liquid-hydrogen target using the CLAS12 spectrometer at Jefferson Lab. Observed non-zero $\sin\Delta\phi$ modulations in $ep \rightarrow e'p\pi^+X$ events, where $\Delta\phi$ is the difference of the azimuthal angles of the proton and pion in the virtual photon and target nucleon center-of-mass frame, indicate that correlations between the spin and transverse momenta of hadrons produced in the target- and current-fragmentation regions may be significant. The measured beam-spin asymmetries provide a first access in dihadron production to a previously unobserved leading-twist spin- and transverse-momentum-dependent fracture function. The fracture functions describe the hadronization of the target remnant after the hard scattering of a virtual photon off a quark in the target particle and provide a new avenue for studying nucleonic structure and hadronization., Comment: 7 pages, 6 figures

Published
2022
Full Text
View/download PDF

12. Alignment of the CLAS12 central hybrid tracker with a Kalman Filter

Author

Paul, S. J., Peck, A., Arratia, M., Gotra, Y., Ziegler, V., De Vita, R., Bossu, F., Defurne, M., Atac, H., Gayoso, C. Ayerbe, Baashen, L., Baltzell, N. A., Barion, L., Bashkanov, M., Battaglieri, M., Bedlinskiy, I., Benkel, B., Benmokhtar, F., Bianconi, A., Biondo, L., Biselli, A. S., Bondi, M., Boiarinov, S., Brinkmann, K. Th., Briscoe, W. J., Brooks, W. K., Bulumulla, D., Burkert, V. D., Capobianco, R., Carman, D. S., Carvajal, J. C., Chatagnon, P., Chesnokov, V., Chetry, T., Ciullo, G., Cole, P. L., Costantini, G., Angelo, A. D, Dashyan, N., Deur, A., Diehl, S., Djalali, C., Dupre, R., Alaoui, A. El, Fassi, L. El, Elouadrhiri, L., Filippi, A., Gates, K., Gavalian, G., Ghandilyan, Y., Gilfoyle, G. P., Golubenko, A. A., Gosta, G., Gothe, R. W., Griffioen, K., Guidal, M., Hakobyan, H., Hattawy, M., Hauenstein, F., Hayward, T. B., Heddle, D., Hobart, A., Holtrop, M., Ilieva, Y., Ireland, D. G., Isupov, E. L., Jo, H. S., Johnston, R., Joo, K., Keller, D., Khachatryan, M., Khanal, A., Kim, A., Kim, W., Klimenko, V., Kripko, A., Lanza, L., Leali, M., Lenisa, P., Li, X., MacGregor, I. J. D., Marchand, D., Marsicano, L., Mascagna, V., McKinnon, B., McLauchlin, C., Migliorati, S., Mineeva, T., Mirazita, M., Mokeev, V., Camacho, C. Munoz, Nadel-Turonski, P., Naidoo, P., Neupane, K., Nguyen, D., Niccolai, S., Nicol, M., Niculescu, G., Osipenko, M., Pandey, P., Paolone, M., Paremuzyan, R., Pilleux, N., Pogorelko, O., Pokhrel, M., Poudel, J., Price, J. W., Prok, Y., Reed, T., Ripani, M., Ritman, J., Sabatie, F., Schadmand, S., Schmidt, A., Shirokov, E. V., Shrestha, U., Simmerling, P., Spreafico, M., Sokhan, D., Sparveris, N., Strakovsky, I. I., Strauch, S., Tan, J. A., Tyson, R., Ungaro, M., Vallarino, S., Venturelli, L., Voskanyan, H., Voutier, E., Watts, D. P., Wei, X., Wishart, R., Wood, M. H., and Zachariou, N.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Nuclear Experiment
Abstract

Several factors can contribute to the difficulty of aligning the sensors of tracking detectors, including a large number of modules, multiple types of detector technologies, and non-linear strip patterns on the sensors. All three of these factors apply to the CLAS12 CVT, which is a hybrid detector consisting of planar silicon sensors with non-parallel strips, and cylindrical micromegas sensors with longitudinal and arc-shaped strips located within a 5~T superconducting solenoid. To align this detector, we used the Kalman Alignment Algorithm, which accounts for correlations between the alignment parameters without requiring the time-consuming inversion of large matrices. This is the first time that this algorithm has been adapted for use with hybrid technologies, non-parallel strips, and curved sensors. We present the results for the first alignment of the CLAS12 CVT using straight tracks from cosmic rays and from a target with the magnetic field turned off. After running this procedure, we achieved alignment at the level of 10~$\mu$m, and the widths of the residual spectra were greatly reduced. These results attest to the flexibility of this algorithm and its applicability to future use in the CLAS12 CVT and other hybrid or curved trackers, such as those proposed for the future Electron-Ion Collider.

Published
2022
Full Text
View/download PDF

13. ECCE unpolarized TMD measurements

Author

Seidl, R., Vladimirov, A., Adkins, J. K., Akiba, Y., Albataineh, A., Amaryan, M., Arsene, I. C., Gayoso, C. Ayerbe, Bae, J., Bai, X., Baker, M. D., Bashkanov, M., Bellwied, R., Benmokhtar, F., Berdnikov, V., Bernauer, J. C., Bock, F., Boeglin, W., Borysova, M., Brash, E., Brindza, P., Briscoe, W. J., Brooks, M., Bueltmann, S., Bukhari, M. H. S., Bylinkin, A., Capobianco, R., Chang, W. -C., Cheon, Y., Chen, K., Chen, K. -F., Cheng, K. -Y., Chiu, M., Chujo, T., Citron, Z., Cline, E., Cohen, E., Cormier, T., Morales, Y. Corrales, Cotton, C., Crafts, J., Crawford, C., Creekmore, S., Cuevas, C., Cunningham, J., David, G., Dean, C. T., Demarteau, M., Diehl, S., Doshita, N., Dupré, R., Durham, J. M., Dzhygadlo, R., Ehlers, R., Fassi, L. El, Emmert, A., Ent, R., Fanelli, C., Fatemi, R., Fegan, S., Finger, M., Finger Jr., M., Frantz, J., Friedman, M., Friscic, I., Gangadharan, D., Gardner, S., Gates, K., Geurts, F., Gilman, R., Glazier, D., Glimos, E., Goto, Y., Grau, N., Greene, S. V., Guo, A. Q., Guo, L., Ha, S. K., Haggerty, J., Hayward, T., He, X., Hen, O., Higinbotham, D. W., Hoballah, M., Horn, T., Hoghmrtsyan, A., Hsu, P. -h. J., Huang, J., Huber, G., Hutson, A., Hwang, K. Y., Hyde, C. E., Inaba, M., Iwata, T., Jo, H. S., Joo, K., Kalantarians, N., Kalicy, G., Kawade, K., Kay, S. J. D., Kim, A., Kim, B., Kim, C., Kim, M., Kim, Y., Kistenev, E., Klimenko, V., Ko, S. H., Korover, I., Korsch, W., Krintiras, G., Kuhn, S., Kuo, C. -M., Kutz, T., Lajoie, J., Lawrence, D., Lebedev, S., Lee, H., Lee, J. S. H., Lee, S. W., Lee, Y. -J., Li, W., Li, X., Liang, Y. T., Lim, S., Lin, C. -H., Lin, D. X., Liu, K., Liu, M. X., Livingston, K., Liyanage, N., Llope, W. J., Loizides, C., Long, E., Lu, R. -S., Lu, Z., Lynch, W., Marchand, D., Marcisovsky, M., Markert, C., Markowitz, P., Marukyan, H., McGaughey, P., Mihovilovic, M., Milner, R. G., Milov, A., Miyachi, Y., Mkrtchyan, A., Monaghan, P., Montgomery, R., Morrison, D., Movsisyan, A., Mkrtchyan, H., Camacho, C. Munoz, Murray, M., Nagai, K., Nagle, J., Nakagawa, I., Nattrass, C., Nguyen, D., Niccolai, S., Nouicer, R., Nukazuka, G., Nycz, M., Okorokov, V. A., Orešić, S., Osborn, J. D., O'Shaughnessy, C., Paganis, S., Papandreou, Z, Pate, S. F., Patel, M., Paus, C., Penman, G., Perdekamp, M. G., Perepelitsa, D. V., da Costa, H. Periera, Peters, K., Phelps, W., Piasetzky, E., Pinkenburg, C., Prochazka, I., Protzman, T., Purschke, M. L., Putschke, J., Pybus, J. R., Rajput-Ghoshal, R., Rasson, J., Raue, B., Read, K., Røed, K., Reed, R., Reinhold, J., Renner, E. L., Richards, J., Riedl, C., Rinn, T., Roche, J., Roland, G. M., Ron, G., Rosati, M., Royon, C., Ryu, J., Salur, S., Santiesteban, N., Santos, R., Sarsour, M., Schambach, J., Schmidt, A., Schmidt, N., Schwarz, C., Schwiening, J., Sickles, A., Simmerling, P., Sirca, S., Sharma, D., Shi, Z., Shibata, T. -A., Shih, C. -W., Shimizu, S., Shrestha, U., Slifer, K., Smith, K., Sokhan, D., Soltz, R., Sondheim, W., Song, J., Strakovsky, I. I., Steinberg, P., Stepanov, P., Stevens, J., Strube, J., Sun, P., Sun, X., Suresh, K., Tadevosyan, V., Tang, W. -C., Araya, S. Tapia, Tarafdar, S., Teodorescu, L., Thomas, D., Timmins, A., Tomasek, L., Trotta, N., Trotta, R., Tveter, T. S., Umaka, E., Usman, A., van Hecke, H. W., Van Hulse, C., Velkovska, J., Voutier, E., Wang, P. K., Wang, Q., Wang, Y., Watts, D. P., Wickramaarachchi, N., Weinstein, L., Williams, M., Wong, C. -P., Wood, L., Wood, M. H., Woody, C., Wyslouch, B., Xiao, Z., Yamazaki, Y., Yang, Y., Ye, Z., Yoo, H. D., Yurov, M., Zachariou, N., Zajc, W. A., Zhang, J., Zhang, Y., Zhao, Y. X., Zheng, X., and Zhuang, P.

Subjects
High Energy Physics - Experiment
Abstract

We performed feasibility studies for various measurements that are related to unpolarized TMD distribution and fragmentation functions. The processes studied include semi-inclusive Deep inelastic scattering (SIDIS) where single hadrons (pions and kaons) were detected in addition to the scattered DIS lepton. The single hadron cross sections and multiplicities were extracted as a function of the DIS variables $x$ and $Q^2$, as well as the semi-inclusive variables $z$, which corresponds to the momentum fraction the detected hadron carries relative to the struck parton and $P_T$, which corresponds to the transverse momentum of the detected hadron relative to the virtual photon. The expected statistical precision of such measurements is extrapolated to accumulated luminosities of 10 fb$^{-1}$ and potential systematic uncertainties are approximated given the deviations between true and reconstructed yields., Comment: 12 pages, 9 figures, to be submitted in joint ECCE proposal NIM-A volume

Published
2022
Full Text
View/download PDF

14. ECCE Sensitivity Studies for Single Hadron Transverse Single Spin Asymmetry Measurements

Author

Seidl, R., Vladimirov, A., Pitonyak, D., Prokudin, A., Adkins, J. K., Akiba, Y., Albataineh, A., Amaryan, M., Arsene, I. C., Gayoso, C. Ayerbe, Bae, J., Bai, X., Baker, M. D., Bashkanov, M., Bellwied, R., Benmokhtar, F., Berdnikov, V., Bernauer, J. C., Bock, F., Boeglin, W., Borysova, M., Brash, E., Brindza, P., Briscoe, W. J., Brooks, M., Bueltmann, S., Bukhari, M. H. S., Bylinkin, A., Capobianco, R., Chang, W. -C., Cheon, Y., Chen, K., Chen, K. -F., Cheng, K. -Y., Chiu, M., Chujo, T., Citron, Z., Cline, E., Cohen, E., Cormier, T., Morales, Y. Corrales, Cotton, C., Crafts, J., Crawford, C., Creekmore, S., Cuevas, C., Cunningham, J., David, G., Dean, C. T., Demarteau, M., Diehl, S., Doshita, N., Dupré, R., Durham, J. M., Dzhygadlo, R., Ehlers, R., Fassi, L. El, Emmert, A., Ent, R., Fanelli, C., Fatemi, R., Fegan, S., Finger, M., Finger Jr., M., Frantz, J., Friedman, M., Friscic, I., Gangadharan, D., Gardner, S., Gates, K., Geurts, F., Gilman, R., Glazier, D., Glimos, E., Goto, Y., Grau, N., Greene, S. V., Guo, A. Q., Guo, L., Ha, S. K., Haggerty, J., Hayward, T., He, X., Hen, O., Higinbotham, D. W., Hoballah, M., Horn, T., Hoghmrtsyan, A., Hsu, P. -h. J., Huang, J., Huber, G., Hutson, A., Hwang, K. Y., Hyde, C. E., Inaba, M., Iwata, T., Jo, H. S., Joo, K., Kalantarians, N., Kalicy, G., Kawade, K., Kay, S. J. D., Kim, A., Kim, B., Kim, C., Kim, M., Kim, Y., Kistenev, E., Klimenko, V., Ko, S. H., Korover, I., Korsch, W., Krintiras, G., Kuhn, S., Kuo, C. -M., Kutz, T., Lajoie, J., Lawrence, D., Lebedev, S., Lee, H., Lee, J. S. H., Lee, S. W., Lee, Y. -J., Li, W., Li, X., Liang, Y. T., Lim, S., Lin, C. -H., Lin, D. X., Liu, K., Liu, M. X., Livingston, K., Liyanage, N., Llope, W. J., Loizides, C., Long, E., Lu, R. -S., Lu, Z., Lynch, W., Marchand, D., Marcisovsky, M., Markert, C., Markowitz, P., Marukyan, H., McGaughey, P., Mihovilovic, M., Milner, R. G., Milov, A., Miyachi, Y., Mkrtchyan, A., Monaghan, P., Montgomery, R., Morrison, D., Movsisyan, A., Mkrtchyan, H., Camacho, C. Munoz, Murray, M., Nagai, K., Nagle, J., Nakagawa, I., Nattrass, C., Nguyen, D., Niccolai, S., Nouicer, R., Nukazuka, G., Nycz, M., Okorokov, V. A., Orešić, S., Osborn, J. D., O'Shaughnessy, C., Paganis, S., Papandreou, Z, Pate, S. F., Patel, M., Paus, C., Penman, G., Perdekamp, M. G., Perepelitsa, D. V., da Costa, H. Periera, Peters, K., Phelps, W., Piasetzky, E., Pinkenburg, C., Prochazka, I., Protzman, T., Purschke, M. L., Putschke, J., Pybus, J. R., Rajput-Ghoshal, R., Rasson, J., Raue, B., Read, K., Røed, K., Reed, R., Reinhold, J., Renner, E. L., Richards, J., Riedl, C., Rinn, T., Roche, J., Roland, G. M., Ron, G., Rosati, M., Royon, C., Ryu, J., Salur, S., Santiesteban, N., Santos, R., Sarsour, M., Schambach, J., Schmidt, A., Schmidt, N., Schwarz, C., Schwiening, J., Sickles, A., Simmerling, P., Sirca, S., Sharma, D., Shi, Z., Shibata, T. -A., Shih, C. -W., Shimizu, S., Shrestha, U., Slifer, K., Smith, K., Sokhan, D., Soltz, R., Sondheim, W., Song, J., Strakovsky, I. I., Steinberg, P., Stepanov, P., Stevens, J., Strube, J., Sun, P., Sun, X., Suresh, K., Tadevosyan, V., Tang, W. -C., Araya, S. Tapia, Tarafdar, S., Teodorescu, L., Thomas, D., Timmins, A., Tomasek, L., Trotta, N., Trotta, R., Tveter, T. S., Umaka, E., Usman, A., van Hecke, H. W., Van Hulse, C., Velkovska, J., Voutier, E., Wang, P. K., Wang, Q., Wang, Y., Watts, D. P., Wickramaarachchi, N., Weinstein, L., Williams, M., Wong, C. -P., Wood, L., Wood, M. H., Woody, C., Wyslouch, B., Xiao, Z., Yamazaki, Y., Yang, Y., Ye, Z., Yoo, H. D., Yurov, M., Zachariou, N., Zajc, W. A., Zhang, J., Zhang, Y., Zhao, Y. X., Zheng, X., and Zhuang, P.

Subjects
High Energy Physics - Experiment
Abstract

We performed feasibility studies for various single transverse spin measurements that are related to the Sivers effect, transversity and the tensor charge, and the Collins fragmentation function. The processes studied include semi-inclusive deep inelastic scattering (SIDIS) where single hadrons (pions and kaons) were detected in addition to the scattered DIS lepton. The data were obtained in {\sc pythia}6 and {\sc geant}4 simulated e+p collisions at 18 GeV on 275 GeV, 18 on 100, 10 on 100, and 5 on 41 that use the ECCE detector configuration. Typical DIS kinematics were selected, most notably $Q^2 > 1 $ GeV$^2$, and cover the $x$ range from $10^{-4}$ to $1$. The single spin asymmetries were extracted as a function of $x$ and $Q^2$, as well as the semi-inclusive variables $z$, and $P_T$. They are obtained in azimuthal moments in combinations of the azimuthal angles of the hadron transverse momentum and transverse spin of the nucleon relative to the lepton scattering plane. The initially unpolarized MonteCarlo was re-weighted in the true kinematic variables, hadron types and parton flavors based on global fits of fixed target SIDIS experiments and $e^+e^-$ annihilation data. The expected statistical precision of such measurements is extrapolated to 10 fb$^{-1}$ and potential systematic uncertainties are approximated given the deviations between true and reconstructed yields. The impact on the knowledge of the Sivers functions, transversity and tensor charges, and the Collins function has then been evaluated in the same phenomenological extractions as in the Yellow Report. The impact is found to be comparable to that obtained with the parameterized Yellow Report detector and shows that the ECCE detector configuration can fulfill the physics goals on these quantities., Comment: 22 pages, 22 figures, to be submitted to joint ECCE proposal NIM-A volume

Published
2022
Full Text
View/download PDF

15. Open Heavy Flavor Studies for the ECCE Detector at the Electron Ion Collider

Author

Li, X., Adkins, J. K., Akiba, Y., Albataineh, A., Amaryan, M., Arsene, I. C., Gayoso, C. Ayerbe, Bae, J., Bai, X., Baker, M. D., Bashkanov, M., Bellwied, R., Benmokhtar, F., Berdnikov, V., Bernauer, J. C., Bock, F., Boeglin, W., Borysova, M., Brash, E., Brindza, P., Briscoe, W. J., Brooks, M., Bueltmann, S., Bukhari, M. H. S., Bylinkin, A., Capobianco, R., Chang, W. -C., Cheon, Y., Chen, K., Chen, K. -F., Cheng, K. -Y., Chiu, M., Chujo, T., Citron, Z., Cline, E., Cohen, E., Cormier, T., Morales, Y. Corrales, Cotton, C., Crafts, J., Crawford, C., Creekmore, S., Cuevas, C., Cunningham, J., David, G., Dean, C. T., Demarteau, M., Diehl, S., Doshita, N., Dupré, R., Durham, J. M., Dzhygadlo, R., Ehlers, R., Fassi, L. El, Emmert, A., Ent, R., Fanelli, C., Fatemi, R., Fegan, S., Finger, M., Finger Jr., M., Frantz, J., Friedman, M., Friscic, I., Gangadharan, D., Gardner, S., Gates, K., Geurts, F., Gilman, R., Glazier, D., Glimos, E., Goto, Y., Grau, N., Greene, S. V., Guo, A. Q., Guo, L., Ha, S. K., Haggerty, J., Hayward, T., He, X., Hen, O., Higinbotham, D. W., Hoballah, M., Horn, T., Hoghmrtsyan, A., Hsu, P. -h. J., Huang, J., Huber, G., Hutson, A., Hwang, K. Y., Hyde, C. E., Inaba, M., Iwata, T., Jo, H. S., Joo, K., Kalantarians, N., Kalicy, G., Kawade, K., Kay, S. J. D., Kim, A., Kim, B., Kim, C., Kim, M., Kim, Y., Kistenev, E., Klimenko, V., Ko, S. H., Korover, I., Korsch, W., Krintiras, G., Kuhn, S., Kuo, C. -M., Kutz, T., Lajoie, J., Lawrence, D., Lebedev, S., Lee, H., Lee, J. S. H., Lee, S. W., Lee, Y. -J., Li, W., Li, W. B., Liang, Y. T., Lim, S., Lin, C. -H., Lin, D. X., Liu, K., Liu, M. X., Livingston, K., Liyanage, N., Llope, W. J., Loizides, C., Long, E., Lu, R. -S., Lu, Z., Lynch, W., Mantry, S., Marchand, D., Marcisovsky, M., Markert, C., Markowitz, P., Marukyan, H., McGaughey, P., Mihovilovic, M., Milner, R. G., Milov, A., Miyachi, Y., Mkrtchyan, A., Monaghan, P., Montgomery, R., Morrison, D., Movsisyan, A., Mkrtchyan, H., Camacho, C. Munoz, Murray, M., Nagai, K., Nagle, J., Nakagawa, I., Nattrass, C., Nguyen, D., Niccolai, S., Nouicer, R., Nukazuka, G., Nycz, M., Okorokov, V. A., Orešić, S., Osborn, J. D., O'Shaughnessy, C., Paganis, S., Papandreou, Z., Pate, S. F., Patel, M., Paus, C., Penman, G., Perdekamp, M. G., Perepelitsa, D. V., da Costa, H. Periera, Peters, K., Phelps, W., Piasetzky, E., Pinkenburg, C., Prochazka, I., Protzman, T., Purschke, M. L., Putschke, J., Pybus, J. R., Rajput-Ghoshal, R., Rasson, J., Raue, B., Read, K. F., Røed, K., Reed, R., Reinhold, J., Renner, E. L., Richards, J., Riedl, C., Rinn, T., Roche, J., Roland, G. M., Ron, G., Rosati, M., Royon, C., Ryu, J., Salur, S., Santiesteban, N., Santos, R., Sarsour, M., Schambach, J., Schmidt, A., Schmidt, N., Schwarz, C., Schwiening, J., Seidl, R., Sickles, A., Simmerling, P., Sirca, S., Sharma, D., Shi, Z., Shibata, T. -A., Shih, C. -W., Shimizu, S., Shrestha, U., Slifer, K., Smith, K., Sokhan, D., Soltz, R., Sondheim, W., Song, J., Strakovsky, I. I., Steinberg, P., Stepanov, P., Stevens, J., Strube, J., Sun, P., Sun, X., Suresh, K., Tadevosyan, V., Tang, W. -C., Araya, S. Tapia, Tarafdar, S., Teodorescu, L., Thomas, D., Timmins, A., Tomasek, L., Trotta, N., Trotta, R., Tveter, T. S., Umaka, E., Usman, A., van Hecke, H. W., Van Hulse, C., Velkovska, J., Voutier, E., Wang, P. K., Wang, Q., Wang, Y., Watts, D. P., Wickramaarachchi, N., Weinstein, L., Williams, M., Wong, C. -P., Wood, L., Wood, M. H., Woody, C., Wyslouch, B., Xiao, Z., Yamazaki, Y., Yang, Y., Ye, Z., Yoo, H. D., Yurov, M., Zachariou, N., Zajc, W. A., Zha, W., Zhang, J. -L., Zhang, J. -X., Zhang, Y., Zhao, Y. -X., Zheng, X., and Zhuang, P.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Nuclear Experiment
Abstract

The ECCE detector has been recommended as the selected reference detector for the future Electron-Ion Collider (EIC). A series of simulation studies have been carried out to validate the physics feasibility of the ECCE detector. In this paper, detailed studies of heavy flavor hadron and jet reconstruction and physics projections with the ECCE detector performance and different magnet options will be presented. The ECCE detector has enabled precise EIC heavy flavor hadron and jet measurements with a broad kinematic coverage. These proposed heavy flavor measurements will help systematically study the hadronization process in vacuum and nuclear medium especially in the underexplored kinematic region., Comment: Open heavy flavor studies with the EIC reference detector design by the ECCE consortium. 11 pages, 11 figures, to be submitted to the Nuclear Instruments and Methods A

Published
2022

16. Exclusive J/$\psi$ Detection and Physics with ECCE

Author

Li, X., Adkins, J. K., Akiba, Y., Albataineh, A., Amaryan, M., Arsene, I. C., Gayoso, C. Ayerbe, Bae, J., Bai, X., Baker, M. D., Bashkanov, M., Bellwied, R., Benmokhtar, F., Berdnikov, V., Bernauer, J. C., Bock, F., Boeglin, W., Borysova, M., Brash, E., Brindza, P., Briscoe, W. J., Brooks, M., Bueltmann, S., Bukhari, M. H. S., Bylinkin, A., Capobianco, R., Chang, W. -C., Cheon, Y., Chen, K., Chen, K. -F., Cheng, K. -Y., Chiu, M., Chujo, T., Citron, Z., Cline, E., Cohen, E., Cormier, T., Morales, Y. Corrales, Cotton, C., Crafts, J., Crawford, C., Creekmore, S., Cuevas, C., Cunningham, J., David, G., Dean, C. T., Demarteau, M., Diehl, S., Doshita, N., Dupré, R., Durham, J. M., Dzhygadlo, R., Ehlers, R., Fassi, L. El, Emmert, A., Ent, R., Fanelli, C., Fatemi, R., Fegan, S., Finger, M., Finger Jr., M., Frantz, J., Friedman, M., Friscic, I., Gangadharan, D., Gardner, S., Gates, K., Geurts, F., Gilman, R., Glazier, D., Glimos, E., Goto, Y., Grau, N., Greene, S. V., Guo, A. Q., Guo, L., Ha, S. K., Haggerty, J., Hayward, T., He, X., Hen, O., Higinbotham, D. W., Hoballah, M., Horn, T., Hoghmrtsyan, A., Hsu, P. -h. J., Huang, J., Huber, G., Hutson, A., Hwang, K. Y., Hyde, C. E., Inaba, M., Iwata, T., Jo, H. S., Joo, K., Kalantarians, N., Kalicy, G., Kawade, K., Kay, S. J. D., Kim, A., Kim, B., Kim, C., Kim, M., Kim, Y., Kistenev, E., Klimenko, V., Ko, S. H., Korover, I., Korsch, W., Krintiras, G., Kuhn, S., Kuo, C. -M., Kutz, T., Lajoie, J., Lawrence, D., Lebedev, S., Lee, H., Lee, J. S. H., Lee, S. W., Lee, Y. -J., Li, W., Li, W. B., Liang, Y. T., Lim, S., Lin, C. -H., Lin, D. X., Liu, K., Liu, M. X., Livingston, K., Liyanage, N., Llope, W. J., Loizides, C., Long, E., Lu, R. -S., Lu, Z., Lynch, W., Mantry, S., Marchand, D., Marcisovsky, M., Markert, C., Markowitz, P., Marukyan, H., McGaughey, P., Mihovilovic, M., Milner, R. G., Milov, A., Miyachi, Y., Mkrtchyan, A., Monaghan, P., Montgomery, R., Morrison, D., Movsisyan, A., Mkrtchyan, H., Camacho, C. Munoz, Murray, M., Nagai, K., Nagle, J., Nakagawa, I., Nattrass, C., Nguyen, D., Niccolai, S., Nouicer, R., Nukazuka, G., Nycz, M., Okorokov, V. A., Orešić, S., Osborn, J. D., O'Shaughnessy, C., Paganis, S., Papandreou, Z., Pate, S. F., Patel, M., Paus, C., Penman, G., Perdekamp, M. G., Perepelitsa, D. V., da Costa, H. Periera, Peters, K., Phelps, W., Piasetzky, E., Pinkenburg, C., Prochazka, I., Protzman, T., Purschke, M. L., Putschke, J., Pybus, J. R., Rajput-Ghoshal, R., Rasson, J., Raue, B., Read, K. F., Røed, K., Reed, R., Reinhold, J., Renner, E. L., Richards, J., Riedl, C., Rinn, T., Roche, J., Roland, G. M., Ron, G., Rosati, M., Royon, C., Ryu, J., Salur, S., Santiesteban, N., Santos, R., Sarsour, M., Schambach, J., Schmidt, A., Schmidt, N., Schwarz, C., Schwiening, J., Seidl, R., Sickles, A., Simmerling, P., Sirca, S., Sharma, D., Shi, Z., Shibata, T. -A., Shih, C. -W., Shimizu, S., Shrestha, U., Slifer, K., Smith, K., Sokhan, D., Soltz, R., Sondheim, W., Song, J., Strakovsky, I. I., Steinberg, P., Stepanov, P., Stevens, J., Strube, J., Sun, P., Sun, X., Suresh, K., Tadevosyan, V., Tang, W. -C., Araya, S. Tapia, Tarafdar, S., Teodorescu, L., Thomas, D., Timmins, A., Tomasek, L., Trotta, N., Trotta, R., Tveter, T. S., Umaka, E., Usman, A., van Hecke, H. W., Van Hulse, C., Velkovska, J., Voutier, E., Wang, P. K., Wang, Q., Wang, Y., Watts, D. P., Wickramaarachchi, N., Weinstein, L., Williams, M., Wong, C. -P., Wood, L., Wood, M. H., Woody, C., Wyslouch, B., Xiao, Z., Yamazaki, Y., Yang, Y., Ye, Z., Yoo, H. D., Yurov, M., Zachariou, N., Zajc, W. A., Zha, W., Zhang, J. -L., Zhang, J. -X., Zhang, Y., Zhao, Y. -X., Zheng, X., and Zhuang, P.

Subjects
Nuclear Experiment, Physics - Instrumentation and Detectors
Abstract

Exclusive heavy quarkonium photoproduction is one of the most popular processes in EIC, which has a large cross section and a simple final state. Due to the gluonic nature of the exchange Pomeron, this process can be related to the gluon distributions in the nucleus. The momentum transfer dependence of this process is sensitive to the interaction sites, which provides a powerful tool to probe the spatial distribution of gluons in the nucleus. Recently the problem of the origin of hadron mass has received lots of attention in determining the anomaly contribution $M_{a}$. The trace anomaly is sensitive to the gluon condensate, and exclusive production of quarkonia such as J/$\psi$ and $\Upsilon$ can serve as a sensitive probe to constrain it. In this paper, we present the performance of the ECCE detector for exclusive J/$\psi$ detection and the capability of this process to investigate the above physics opportunities with ECCE., Comment: 11 pages, 14 figures, 1 table

Published
2022
Full Text
View/download PDF

17. Search for $e\to\tau$ Charged Lepton Flavor Violation at the EIC with the ECCE Detector

Author

Zhang, J. -L., Mantry, S., Adkins, J. K., Akiba, Y., Albataineh, A., Amaryan, M., Arsene, I. C., Gayoso, C. Ayerbe, Bae, J., Bai, X., Baker, M. D., Bashkanov, M., Bellwied, R., Benmokhtar, F., Berdnikov, V., Bernauer, J. C., Bock, F., Boeglin, W., Borysova, M., Brash, E., Brindza, P., Briscoe, W. J., Brooks, M., Bueltmann, S., Bukhari, M. H. S., Bylinkin, A., Capobianco, R., Chang, W. -C., Cheon, Y., Chen, K., Chen, K. -F., Cheng, K. -Y., Chiu, M., Chujo, T., Citron, Z., Cline, E., Cohen, E., Cormier, T., Morales, Y. Corrales, Cotton, C., Crafts, J., Crawford, C., Creekmore, S., Cuevas, C., Cunningham, J., David, G., Dean, C. T., Demarteau, M., Diehl, S., Doshita, N., Dupré, R., Durham, J. M., Dzhygadlo, R., Ehlers, R., Fassi, L. El, Emmert, A., Ent, R., Fanelli, C., Fatemi, R., Fegan, S., Finger, M., Finger Jr., M., Frantz, J., Friedman, M., Friscic, I., Gangadharan, D., Gardner, S., Gates, K., Geurts, F., Gilman, R., Glazier, D., Glimos, E., Goto, Y., Grau, N., Greene, S. V., Guo, A. Q., Guo, L., Ha, S. K., Haggerty, J., Hayward, T., He, X., Hen, O., Higinbotham, D. W., Hoballah, M., Horn, T., Hoghmrtsyan, A., Hsu, P. -h. J., Huang, J., Huber, G., Hutson, A., Hwang, K. Y., Hyde, C. E., Inaba, M., Iwata, T., Jo, H. S., Joo, K., Kalantarians, N., Kalicy, G., Kawade, K., Kay, S. J. D., Kim, A., Kim, B., Kim, C., Kim, M., Kim, Y., Kistenev, E., Klimenko, V., Ko, S. H., Korover, I., Korsch, W., Krintiras, G., Kuhn, S., Kuo, C. -M., Kutz, T., Lajoie, J., Lawrence, D., Lebedev, S., Lee, H., Lee, J. S. H., Lee, S. W., Lee, Y. -J., Li, W., Li, W. B., Li, X., Liang, Y. T., Lim, S., Lin, C. -H., Lin, D. X., Liu, K., Liu, M. X., Livingston, K., Liyanage, N., Llope, W. J., Loizides, C., Long, E., Lu, R. -S., Lu, Z., Lynch, W., Marchand, D., Marcisovsky, M., Markert, C., Markowitz, P., Marukyan, H., McGaughey, P., Mihovilovic, M., Milner, R. G., Milov, A., Miyachi, Y., Mkrtchyan, A., Monaghan, P., Montgomery, R., Morrison, D., Movsisyan, A., Mkrtchyan, H., Camacho, C. Munoz, Murray, M., Nagai, K., Nagle, J., Nakagawa, I., Nattrass, C., Nguyen, D., Niccolai, S., Nouicer, R., Nukazuka, G., Nycz, M., Okorokov, V. A., Orešić, S., Osborn, J. D., O'Shaughnessy, C., Paganis, S., Papandreou, Z., Pate, S. F., Patel, M., Paus, C., Penman, G., Perdekamp, M. G., Perepelitsa, D. V., da Costa, H. Periera, Peters, K., Phelps, W., Piasetzky, E., Pinkenburg, C., Prochazka, I., Protzman, T., Purschke, M. L., Putschke, J., Pybus, J. R., Rajput-Ghoshal, R., Rasson, J., Raue, B., Read, K. F., Røed, K., Reed, R., Reinhold, J., Renner, E. L., Richards, J., Riedl, C., Rinn, T., Roche, J., Roland, G. M., Ron, G., Rosati, M., Royon, C., Ryu, J., Salur, S., Santiesteban, N., Santos, R., Sarsour, M., Schambach, J., Schmidt, A., Schmidt, N., Schwarz, C., Schwiening, J., Seidl, R., Sickles, A., Simmerling, P., Sirca, S., Sharma, D., Shi, Z., Shibata, T. -A., Shih, C. -W., Shimizu, S., Shrestha, U., Slifer, K., Smith, K., Sokhan, D., Soltz, R., Sondheim, W., Song, J., Strakovsky, I. I., Steinberg, P., Stepanov, P., Stevens, J., Strube, J., Sun, P., Sun, X., Suresh, K., Tadevosyan, V., Tang, W. -C., Araya, S. Tapia, Tarafdar, S., Teodorescu, L., Thomas, D., Timmins, A., Tomasek, L., Trotta, N., Trotta, R., Tveter, T. S., Umaka, E., Usman, A., van Hecke, H. W., Van Hulse, C., Velkovska, J., Voutier, E., Wang, P. K., Wang, Q., Wang, Y., Watts, D. P., Wickramaarachchi, N., Weinstein, L., Williams, M., Wong, C. -P., Wood, L., Wood, M. H., Woody, C., Wyslouch, B., Xiao, Z., Yamazaki, Y., Yang, Y., Ye, Z., Yoo, H. D., Yurov, M., Zachariou, N., Zajc, W. A., Zha, W., Zhang, J. -X., Zhang, Y., Zhao, Y. -X., Zheng, X., and Zhuang, P.

Subjects
High Energy Physics - Phenomenology
Abstract

The recently approved Electron-Ion Collider (EIC) will provide a unique new opportunity for searches of charged lepton flavor violation (CLFV) and other new physics scenarios. In contrast to the $e \leftrightarrow \mu$ CLFV transition for which very stringent limits exist, there is still a relatively large discovery space for the $e \to \tau$ CLFV transition, potentially to be explored by the EIC. With the latest detector design of ECCE (EIC Comprehensive Chromodynamics Experiment) and projected integral luminosity of the EIC, we find the $\tau$-leptons created in the DIS process $ep\to \tau X$ are expected to be identified with high efficiency. A first ECCE simulation study, restricted to the 3-prong $\tau$-decay mode and with limited statistics for the Standard Model backgrounds, estimates that the EIC will be able to improve the current exclusion limit on $e\to \tau$ CLFV by an order of magnitude., Comment: 11 pages, 8 figures, to be submitted to NIM

Published
2022
Full Text
View/download PDF

18. Design and Simulated Performance of Calorimetry Systems for the ECCE Detector at the Electron Ion Collider

Author

Bock, F., Schmidt, N., Wang, P. K., Santiesteban, N., Horn, T., Huang, J., Lajoie, J., Camacho, C. Munoz, Adkins, J. K., Akiba, Y., Albataineh, A., Amaryan, M., Arsene, I. C., Gayoso, C. Ayerbe, Bae, J., Bai, X., Baker, M. D., Bashkanov, M., Bellwied, R., Benmokhtar, F., Berdnikov, V., Bernauer, J. C., Boeglin, W., Borysova, M., Brash, E., Brindza, P., Briscoe, W. J., Brooks, M., Bueltmann, S., Bukhari, M. H. S., Bylinkin, A., Capobianco, R., Chang, W. -C., Cheon, Y., Chen, K., Chen, K. -F., Cheng, K. -Y., Chiu, M., Chujo, T., Citron, Z., Cline, E., Cohen, E., Cormier, T., Morales, Y. Corrales, Cotton, C., Crafts, J., Crawford, C., Creekmore, S., Cuevas, C., Cunningham, J., David, G., Dean, C. T., Demarteau, M., Diehl, S., Doshita, N., Dupre, R., Durham, J. M., Dzhygadlo, R., Ehlers, R., Fassi, L. El, Emmert, A., Ent, R., Fanelli, C., Fatemi, R., Fegan, S., Finger, M., Finger Jr., M., Frantz, J., Friedman, M., Friscic, I., Gangadharan, D., Gardner, S., Gates, K., Geurts, F., Gilman, R., Glazier, D., Glimos, E., Goto, Y., Grau, N., Greene, S. V., Guo, A. Q., Guo, L., Ha, S. K., Haggerty, J., Hayward, T., He, X., Hen, O., Higinbotham, D. W., Hoballah, M., Hoghmrtsyan, A., Hsu, P. -h. J., Huber, G., Hutson, A., Hwang, K. Y., Hyde, C. E., Inaba, M., Iwata, T., Jo, H. S., Joo, K., Kalantarians, N., Kalicy, G., Kawade, K., Kay, S. J. D., Kim, A., Kim, B., Kim, C., Kim, M., Kim, Y., Kistenev, E., Klimenko, V., Ko, S. H., Korover, I., Korsch, W., Krintiras, G., Kuhn, S., Kuo, C. -M., Kutz, T., Lawrence, D., Lebedev, S., Lee, H., Lee, J. S. H., Lee, S. W., Lee, Y. -J., Li, W., Li, W. B., Li, X., Liang, Y. T., Lim, S., Lin, C. -h., Lin, D. X., Liu, K., Liu, M. X., Livingston, K., Liyanage, N., Llope, W. J., Loizides, C., Long, E., Lu, R. -S., Lu, Z., Lynch, W., Mantry, S., Marchand, D., Marcisovsky, M., Markert, C., Markowitz, P., Marukyan, H., McGaughey, P., Mihovilovic, M., Milner, R. G., Milov, A., Miyachi, Y., Mkrtchyan, A., Monaghan, P., Montgomery, R., Morrison, D., Movsisyan, A., Mkrtchyan, H., Murray, M., Nagai, K., Nagle, J., Nakagawa, I., Nattrass, C., Nguyen, D., Niccolai, S., Nouicer, R., Nukazuka, G., Nycz, M., Okorokov, V. A., Oresic, S., Osborn, J. D., Shaughnessy, C. O, Paganis, S., Papandreou, Z., Pate, S. F., Patel, M., Paus, C., Penman, G., Perdekamp, M. G., Perepelitsa, D. V., da Costa, H. Periera, Peters, K., Phelps, W., Piasetzky, E., Pinkenburg, C., Prochazka, I., Protzman, T., Purschke, M. L., Putschke, J., Pybus, J. R., Rajput-Ghoshal, R., Rasson, J., Raue, B., Read, K. F., Røed, K., Reed, R., Reinhold, J., Renner, E. L., Richards, J., Riedl, C., Rinn, T., Roche, J., Roland, G. M., Ron, G., Rosati, M., Royon, C., Ryu, J., Salur, S., Santos, R., Sarsour, M., Schambach, J., Schmidt, A., Schwarz, C., Schwiening, J., Seidl, R., Sickles, A., Simmerling, P., Sirca, S., Sharma, D., Shi, Z., Shibata, T. -A., Shih, C. -W., Shimizu, S., Shrestha, U., Slifer, K., Smith, K., Sokhan, D., Soltz, R., Sondheim, W., Song, J., Strakovsky, I. I., Steinberg, P., Stepanov, P., Stevens, J., Strube, J., Sun, P., Sun, X., Suresh, K., Tadevosyan, V., Tang, W. -C., Araya, S. Tapia, Tarafdar, S., Teodorescu, L., Thomas, D., Timmins, A., Tomasek, L., Trotta, N., Trotta, R., Tveter, T. S., Umaka, E., Usman, A., van Hecke, H. W., Van Hulse, C., Velkovska, J., Voutier, E., Wang, Q., Wang, Y., Watts, D. P., Wickramaarachchi, N., Weinstein, L., Williams, M., Wong, C. -P., Wood, L., Wood, M. H., Woody, C., Wyslouch, B., Xiao, Z., Yamazaki, Y., Yang, Y., Ye, Z., Yoo, H. D., Yurov, M., Zachariou, N., Zajc, W. A., Zha, W., Zhang, J. -L., Zhang, J. -X., Zhang, Y., Zhao, Y. -X., Zheng, X., and Zhuang, P.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Nuclear Experiment
Abstract

We describe the design and performance the calorimeter systems used in the ECCE detector design to achieve the overall performance specifications cost-effectively with careful consideration of appropriate technical and schedule risks. The calorimeter systems consist of three electromagnetic calorimeters, covering the combined pseudorapdity range from -3.7 to 3.8 and two hadronic calorimeters. Key calorimeter performances which include energy and position resolutions, reconstruction efficiency, and particle identification will be presented., Comment: 19 pages, 22 figures, 5 tables

Published
2022
Full Text
View/download PDF

19. Observation of azimuth-dependent suppression of hadron pairs in electron scattering off nuclei

Author

Paul, S. J., Moran, S., Arratia, M., Alaoui, A. El, Hakobyan, H., Brooks, W., Amaryan, M. J., Armstrong, W. R., Atac, H., Baashen, L., Baltzell, N. A., Barion, L., Bashkanov, M., Battaglieri, M., Bedlinskiy, I., Benkel, B., Benmokhtar, F., Bianconi, A., Biondo, L., Biselli, A. S., Bondi, M., Bossu, F., Boiarinov, S., Brinkmann, K. Th., Briscoe, W. J., Bulumulla, D., Burkert, V. D., Capobianco, R., Carman, D. S., Celentano, A., Chesnokov, V., Chetry, T., Ciullo, G., Cole, P. L., Contalbrigo, M., Costantini, G., D'Angelo, A., Dashyan, N., De Vita, R., Defurne, M., Deur, A., Diehl, S., Dilks, C., Djalali, C., Dupre, R., Egiyan, H., Fassi, L. El, Eugenio, P., Fegan, S., Filippi, A., Gavalian, G., Ghandilyan, Y., Gilfoyle, G. P., Golubenko, A. A., Gosta, G., Gothe, R. W., Griffioen, K. A., Guidal, M., Hattawy, M., Hayward, T. B., Heddle, D., Hobart, A., Holtrop, M., Ilieva, Y., Ireland, D. G., Isupov, E. L., Jo, H. S., Johnston, R., Joo, K., Joosten, S., Keller, D., Khanal, A., Khandaker, M., Kim, W., Kripko, A., Kubarovsky, V., Lagerquist, V., Lanza, L., Leali, M., Lee, S., Lenisa, P., Li, X., Livingston, K., MacGregor, I. J. D., Marchand, D., Mascagna, V., McKinnon, B., Meziani, Z. E., Migliorati, S., Milner, R. G., Mineeva, T., Mirazita, M., Mokeev, V. I., Moran, P., Camacho, C. Munoz, Neupane, K., Nguyen, D., Niccolai, S., Niculescu, G., Osipenko, M., Ostrovidov, A. I., Pandey, P., Paolone, M., Pappalardo, L. L., Paremuzyan, R., Pasyuk, E., Phelps, W., Pilleux, N., Pocanic, D., Pogorelko, O., Pokhrel, M., Poudel, J., Price, J. W., Prok, Y., Raue, B. A., Reed, T., Ripani, M., Rosner, G., Sabatie, F., Salgado, C., Schmidt, A., Schumacher, R. A., Sharabian, Y. G., Shirokov, E. V., Shrestha, U., Simmerling, P., Sokhan, D., Sparveris, N., Stepanyan, S., Strakovsky, I. I., Strauch, S., Tan, J. A., Tyson, R., Ungaro, M., Vallarino, S., Venturelli, L., Voskanyan, H., Voutier, E., Wei, X., Wishart, R., Wood, M. H., Zachariou, N., Zhao, Z. W., Ziegler, V., and Zurek, M.

Subjects
Nuclear Experiment
Abstract

We present the first measurement of di-hadron angular correlations in electron-nucleus scattering. The data were taken with the CLAS detector and a 5.0 GeV electron beam incident on deuterium, carbon, iron, and lead targets. Relative to deuterium, the nuclear yields of charged-pion pairs show a strong suppression for azimuthally opposite pairs, no suppression for azimuthally nearby pairs, and an enhancement of pairs with large invariant mass. These effects grow with increased nuclear size. The data are qualitatively described by the GiBUU model, which suggests that hadrons form near the nuclear surface and undergo multiple-scattering in nuclei. These results show that angular correlation studies can open a new way to elucidate how hadrons form and interact inside nuclei, Comment: 6 pages, 4 figures

Published
2022
Full Text
View/download PDF

20. AI-assisted Optimization of the ECCE Tracking System at the Electron Ion Collider

Author

Fanelli, C., Papandreou, Z., Suresh, K., Adkins, J. K., Akiba, Y., Albataineh, A., Amaryan, M., Arsene, I. C., Gayoso, C. Ayerbe, Bae, J., Bai, X., Baker, M. D., Bashkanov, M., Bellwied, R., Benmokhtar, F., Berdnikov, V., Bernauer, J. C., Bock, F., Boeglin, W., Borysova, M., Brash, E., Brindza, P., Briscoe, W. J., Brooks, M., Bueltmann, S., Bukhari, M. H. S., Bylinkin, A., Capobianco, R., Chang, W. -C., Cheon, Y., Chen, K., Chen, K. -F., Cheng, K. -Y., Chiu, M., Chujo, T., Citron, Z., Cline, E., Cohen, E., Cormier, T., Morales, Y. Corrales, Cotton, C., Crafts, J., Crawford, C., Creekmore, S., Cuevas, C., Cunningham, J., David, G., Dean, C. T., Demarteau, M., Diehl, S., Doshita, N., Dupre, R., Durham, J. M., Dzhygadlo, R., Ehlers, R., Fassi, L. El, Emmert, A., Ent, R., Fatemi, R., Fegan, S., Finger, M., Finger Jr., M., Frantz, J., Friedman, M., Friscic, I., Gangadharan, D., Gardner, S., Gates, K., Geurts, F., Gilman, R., Glazier, D., Glimos, E., Goto, Y., Grau, N., Greene, S. V., Guo, A. Q., Guo, L., Ha, S. K., Haggerty, J., Hayward, T., He, X., Hen, O., Higinbotham, D. W., Hoballah, M., Horn, T., Hoghmrtsyan, A., Hsu, P. -h. J., Huang, J., Huber, G., Hutson, A., Hwang, K. Y., Hyde, C., Inaba, M., Iwata, T., Jo, H. S., Joo, K., Kalantarians, N., Kalicy, G., Kawade, K., Kay, S. J. D., Kim, A., Kim, B., Kim, C., Kim, M., Kim, Y., Kistenev, E., Klimenko, V., Ko, S. H., Korover, I., Korsch, W., Krintiras, G., Kuhn, S., Kuo, C. -M., Kutz, T., Lajoie, J., Lawrence, D., Lebedev, S., Lee, H., Lee, J. S. H., Lee, S. W., Lee, Y. -J., Li, W., Li, W. B., Li, X., Liang, Y. T., Lim, S., Lin, C. -h., Lin, D. X., Liu, K., Liu, M. X., Livingston, K., Liyanage, N., Llope, W. J., Loizides, C., Long, E., Lu, R. -S., Lu, Z., Lynch, W., Marchand, D., Marcisovsky, M., Markowitz, P., Marukyan, H., McGaughey, P., Mihovilovic, M., Milner, R. G., Milov, A., Miyachi, Y., Mkrtchyan, A., Monaghan, P., Montgomery, R., Morrison, D., Movsisyan, A., Mkrtchyan, H., Camacho, C. Munoz, Murray, M., Nagai, K., Nagle, J., Nakagawa, I., Nattrass, C., Nguyen, D., Niccolai, S., Nouicer, R., Nukazuka, G., Nycz, M., Okorokov, V. A., Oresic, S., Osborn, J. D., O'Shaughnessy, C., Paganis, S., Pate, S. F., Patel, M., Paus, C., Penman, G., Perdekamp, M. G., Perepelitsa, D. V., da Costa, H. Periera, Peters, K., Phelps, W., Piasetzky, E., Pinkenburg, C., Prochazka, I., Protzman, T., Purschke, M. L., Putschke, J., Pybus, J. R., Rajput-Ghoshal, R., Rasson, J., Raue, B., Read, K. F., Roed, K., Reed, R., Reinhold, J., Renner, E. L., Richards, J., Riedl, C., Rinn, T., Roche, J., Roland, G. M., Ron, G., Rosati, M., Royon, C., Ryu, J., Salur, S., Santiesteban, N., Santos, R., Sarsour, M., Schambach, J., Schmidt, A., Schmidt, N., Schwarz, C., Schwiening, J., Seidl, R., Sickles, A., Simmerling, P., Sirca, S., Sharma, D., Shi, Z., Shibata, T. -A., Shih, C. -W., Shimizu, S., Shrestha, U., Slifer, K., Smith, K., Sokhan, D., Soltz, R., Sondheim, W., Song, J., Strakovsky, I. I., Steinberg, P., Stepanov, P., Stevens, J., Strube, J., Sun, P., Sun, X., Tadevosyan, V., Tang, W. -C., Araya, S. Tapia, Tarafdar, S., Teodorescu, L., Timmins, A., Tomasek, L., Trotta, N., Trotta, R., Tveter, T. S., Umaka, E., Usman, A., van Hecke, H. W., Van Hulse, C., Velkovska, J., Voutier, E., Wang, P. K., Wang, Q., Wang, Y., Watts, D. P., Wickramaarachchi, N., Weinstein, L., Williams, M., Wong, C. -P., Wood, L., Wood, M. H., Woody, C., Wyslouch, B., Xiao, Z., Yamazaki, Y., Yang, Y., Ye, Z., Yoo, H. D., Yurov, M., Zachariou, N., Zajc, W. A., Zha, W., Zhang, J., Zhang, Y., Zhao, Y. X., Zheng, X., and Zhuang, P.

Subjects
Physics - Instrumentation and Detectors, Computer Science - Machine Learning, High Energy Physics - Experiment, Nuclear Experiment, Physics - Computational Physics
Abstract

The Electron-Ion Collider (EIC) is a cutting-edge accelerator facility that will study the nature of the "glue" that binds the building blocks of the visible matter in the universe. The proposed experiment will be realized at Brookhaven National Laboratory in approximately 10 years from now, with detector design and R&D currently ongoing. Notably, EIC is one of the first large-scale facilities to leverage Artificial Intelligence (AI) already starting from the design and R&D phases. The EIC Comprehensive Chromodynamics Experiment (ECCE) is a consortium that proposed a detector design based on a 1.5T solenoid. The EIC detector proposal review concluded that the ECCE design will serve as the reference design for an EIC detector. Herein we describe a comprehensive optimization of the ECCE tracker using AI. The work required a complex parametrization of the simulated detector system. Our approach dealt with an optimization problem in a multidimensional design space driven by multiple objectives that encode the detector performance, while satisfying several mechanical constraints. We describe our strategy and show results obtained for the ECCE tracking system. The AI-assisted design is agnostic to the simulation framework and can be extended to other sub-detectors or to a system of sub-detectors to further optimize the performance of the EIC detector., Comment: 16 pages, 18 figures, 2 appendices, 3 tables

Published
2022
Full Text
View/download PDF

21. Scientific Computing Plan for the ECCE Detector at the Electron Ion Collider

Author

Bernauer, J. C., Dean, C. T., Fanelli, C., Huang, J., Kauder, K., Lawrence, D., Osborn, J. D., Paus, C., Adkins, J. K., Akiba, Y., Albataineh, A., Amaryan, M., Arsene, I. C., Gayoso, C. Ayerbe, Bae, J., Bai, X., Baker, M. D., Bashkanov, M., Bellwied, R., Benmokhtar, F., Berdnikov, V., Bock, F., Boeglin, W., Borysova, M., Brash, E., Brindza, P., Briscoe, W. J., Brooks, M., Bueltmann, S., Bukhari, M. H. S., Bylinkin, A., Capobianco, R., Chang, W. -C., Cheon, Y., Chen, K., Chen, K. -F., Cheng, K. -Y., Chiu, M., Chujo, T., Citron, Z., Cline, E., Cohen, E., Cormier, T., Morales, Y. Corrales, Cotton, C., Crafts, J., Crawford, C., Creekmore, S., Cuevas, C., Cunningham, J., David, G., Demarteau, M., Diehl, S., Doshita, N., Dupré, R., Durham, J. M., Dzhygadlo, R., Ehlers, R., Fassi, L. El, Emmert, A., Ent, R., Fatemi, R., Fegan, S., Finger, M., Finger Jr., M., Frantz, J., Friedman, M., Friscic, I., Gangadharan, D., Gardner, S., Gates, K., Geurts, F., Gilman, R., Glazier, D., Glimos, E., Goto, Y., Grau, N., Greene, S. V., Guo, A. Q., Guo, L., Ha, S. K., Haggerty, J., Hayward, T., He, X., Hen, O., Higinbotham, D. W., Hoballah, M., Horn, T., Hoghmrtsyan, A., Hsu, P. -h. J., Huber, G., Hutson, A., Hwang, K. Y., Hyde, C., Inaba, M., Iwata, T., Jo, H. S., Joo, K., Kalantarians, N., Kalicy, G., Kawade, K., Kay, S. J. D., Kim, A., Kim, B., Kim, C., Kim, M., Kim, Y., Kistenev, E., Klimenko, V., Ko, S. H., Korover, I., Korsch, W., Krintiras, G., Kuhn, S., Kuo, C. -M., Kutz, T., Lajoie, J., Lebedev, S., Lee, H., Lee, J. S. H., Lee, S. W., Lee, Y. -J., Li, W., Li, X., Liang, Y. T., Lim, S., Lin, C. -h., Lin, D. X., Liu, K., Liu, M. X., Livingston, K., Liyanage, N., Llope, W. J., Loizides, C., Long, E., Lu, R. -S., Lu, Z., Lynch, W., Marchand, D., Marcisovsky, M., Markowitz, P., Marukyan, H., McGaughey, P., Mihovilovic, M., Milner, R. G., Milov, A., Miyachi, Y., Mkrtchyan, A., Monaghan, P., Montgomery, R., Morrison, D., Movsisyan, A., Mkrtchyan, H., Camacho, C. Munoz, Murray, M., Nagai, K., Nagle, J., Nakagawa, I., Nattrass, C., Nguyen, D., Niccolai, S., Nouicer, R., Nukazuka, G., Nycz, M., Okorokov, V. A., Orešić, S., O'Shaughnessy, C., Paganis, S., Papandreou, Z, Pate, S. F., Patel, M., Penman, G., Perdekamp, M. G., Perepelitsa, D. V., da Costa, H. Periera, Peters, K., Phelps, W., Piasetzky, E., Pinkenburg, C., Prochazka, I., Protzman, T., Purschke, M. L., Putschke, J., Pybus, J. R., Rajput-Ghoshal, R., Rasson, J., Raue, B., Read, K., Røed, K., Reed, R., Reinhold, J., Renner, E. L., Richards, J., Riedl, C., Rinn, T., Roche, J., Roland, G. M., Ron, G., Rosati, M., Royon, C., Ryu, J., Salur, S., Santiesteban, N., Santos, R., Sarsour, M., Schambach, J., Schmidt, A., Schmidt, N., Schwarz, C., Schwiening, J., Seidl, R., Sickles, A., Simmerling, P., Sirca, S., Sharma, D., Shi, Z., Shibata, T. -A., Shih, C. -W., Shimizu, S., Shrestha, U., Slifer, K., Smith, K., Sokhan, D., Soltz, R., Sondheim, W., Song, J., Strakovsky, I. I., Steinberg, P., Stepanov, P., Stevens, J., Strube, J., Sun, P., Sun, X., Suresh, K., Tadevosyan, V., Tang, W. -C., Araya, S. Tapia, Tarafdar, S., Teodorescu, L., Timmins, A., Tomasek, L., Trotta, N., Trotta, R., Tveter, T. S., Umaka, E., Usman, A., van Hecke, H. W., Van Hulse, C., Velkovska, J., Voutier, E., Wang, P. K., Wang, Q., Wang, Y., Watts, D. P., Wickramaarachchi, N., Weinstein, L., Williams, M., Wong, C. -P., Wood, L., Wood, M. H., Woody, C., Wyslouch, B., Xiao, Z., Yamazaki, Y., Yang, Y., Ye, Z., Yoo, H. D., Yurov, M., Zachariou, N., Zajc, W. A., Zhang, J., Zhang, Y., Zhao, Y. X., Zheng, X., and Zhuang, P.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Nuclear Experiment, Physics - Computational Physics
Abstract

The Electron Ion Collider (EIC) is the next generation of precision QCD facility to be built at Brookhaven National Laboratory in conjunction with Thomas Jefferson National Laboratory. There are a significant number of software and computing challenges that need to be overcome at the EIC. During the EIC detector proposal development period, the ECCE consortium began identifying and addressing these challenges in the process of producing a complete detector proposal based upon detailed detector and physics simulations. In this document, the software and computing efforts to produce this proposal are discussed; furthermore, the computing and software model and resources required for the future of ECCE are described.

Published
2022
Full Text
View/download PDF

22. BioMThermDB 1.0: Thermophysical Database of Proteins in Solutions

Author

Nikolić, Mina, Brudar, Sandi, Coutsias, Evangelos, Dill, Ken A, Lukšič, Miha, Simmerling, Carlos, and Hribar-Lee, Barbara

Subjects
Biological Sciences, Bioinformatics and Computational Biology, Solutions, Viscosity, Proteins, Hydrodynamics, Water, cloud-point temperature, database, diffusion coefficient, electrophoretic mobility, hydrodynamic radius, proteins, solutions, thermodynamics, viscosity, zeta potential, Other Chemical Sciences, Genetics, Other Biological Sciences, Chemical Physics, Biochemistry and cell biology, Microbiology, Medicinal and biomolecular chemistry
Abstract

We present here a freely available web-based database, called BioMThermDB 1.0, of thermophysical and dynamic properties of various proteins and their aqueous solutions. It contains the hydrodynamic radius, electrophoretic mobility, zeta potential, self-diffusion coefficient, solution viscosity, and cloud-point temperature, as well as the conditions for those determinations and details of the experimental method. It can facilitate the meta-analysis and visualization of data, can enable comparisons, and may be useful for comparing theoretical model predictions with experiments.

Published
2022

23. Exclusive $\pi^{-}$ Electroproduction off the Neutron in Deuterium in the Resonance Region

Author

Tian, Y., Gothe, R. W., Mokeev, V. I., Hollis, G., Amaryan, M. J., Armstrong, W. R., Atac, H., Avakian, H., Barion, L., Battaglieri, M., Bedlinskiy, I., Benkel, B., Benmokhtar, F., Bianconi, A., Biondo, L., Biselli, A., Bossù, F., Boiarinov, S., Bondì, M., Brinkmann, K. T., Briscoe, W. J., Bueltmann, S., Bulumulla, D., Burkert, V. D., Capobianco, R., Carman, D. S., Carvajal, J. C., Celentano, A., Chesnokov, V., Chetry, T., Ciullo, G., Clash, G., Cole, P. L., Contalbrigo, M., Costantini, G., D'Angelo, A., Dashyan, N., De Vita, R., Defurne, M., Deur, A., Diehl, S., Djalali, C., Dupre, R., Egiyan, H., Alaoui, A. El, Fassi, L. El, Elouadrhiri, L., Eugenio, P., Fegan, S., Filippi, A., Gavalian, G., Gilfoyle, G. P., Girod, F. X., Golubenko, A. A., Gosta, G., Griffioen, K., Guidal, M., Hakobyan, H., Hattawy, M., Hayward, T. B., Hobart, A., Holtrop, M., Ilieva, Y., Ireland, D. G., Isupov, E. L., Jenkins, D., Jo, H. S., Joo, K., Joosten, S., Keller, D., Khanal, A., Khandaker, M., Kim, A., Kim, W., Klein, F. J., Kripko, A., Kubarovsky, V., Lagerquist, V., Lanza, L., Leali, M., Lenisa, P., Livingston, K., MacGregor, I. . J . D., Marchand, D., Marsicano, L., Mascagna, V., McKinnon, B., Migliorati, S., Mineeva, T., Mirazita, M., Camacho, C. Munoz, Nadel-Turonski, P., Naidoo, P., Neupane, K., Newton, J., Niccolai, S., Nicol, M., Niculescu, G., Osipenko, M., Pandey, P., Paolone, M., Pappalardo, L. L., Paremuzyan, R., Park, K., Pasyuk, E., Paul, S. J., Phelps, W., Pilleux, N., Počanić, D., Pogorelko, O., Poudel, J., Price, J. W., Prok, Y., Reed, T., Ripani, M., Ritman, J., Rizzo, A., Rosner, G., Sabatié, F., Salgado, C., Schadmand, S., Schmidt, A., Schumacher, R. A., Shirokov, E. V., Shrestha, U., Simmerling, P., Sokhan, D., Sparveris, N., Stepanyan, S., Strakovsky, I. I., Strauch, S., Tyson, R., Ungaro, M., Venturelli, L., Voskanyan, H., Voutier, E., Watts, D. P., Wei, K., Wei, X., Wood, M. H., Yale, B., Zachariou, N., and Zhang, J.

Subjects
Nuclear Experiment
Abstract

New results for the exclusive and quasi-free cross sections off neutrons bound in deuterium ${\gamma}_vn(p) \rightarrow p{\pi}^{-} (p)$ are presented over a wide final state hadron angle range with a kinematic coverage of the invariant mass ($W$) up to 1.825 GeV and the virtual photon four-momentum transfer squared ($Q^{2}$) from 0.4 to 1.0 GeV$^2$. The exclusive structure functions were extracted and their Legendre moments were obtained. Final-state-interaction contributions have been kinematically separated from the extracted quasi-free cross sections off bound neutrons solely based on the analysis of the experimental data. These new results will serve as long-awaited input for phenomenological analyses to extract the $Q^{2}$ evolution of previously unavailable $n \to N^{*}$ electroexcitation amplitudes and to improve state-of-the-art models of neutrino scattering off nuclei by augmenting the already available results from free protons., Comment: The author list has been updated

Published
2022
Full Text
View/download PDF

24. Beam-Recoil Transferred Polarization in $K^+Y$ Electroproduction in the Nucleon Resonance Region with CLAS12

Author

Carman, D. S., D'Angelo, A., Lanza, L., Mokeev, V. I., Adhikari, K. P., Amaryan, M. J., Armstrong, W. R., Atac, H., Avakian, H., Gayoso, C. Ayerbe, Baltzell, N. A., Barion, L., Battaglieri, M., Bedlinskiy, I., Benkel, B., Bianconi, A., Biselli, A. S., Bondi, M., Boiarinov, S., Bossu, F., Briscoe, W. J., Bueltmann, S., Bulumulla, D., Burkert, V. D., Capobianco, R., Carvajal, J. C., Celentano, A., Chatagnon, P., Chesnokov, V., Chetry, T., Ciullo, G., Clark, L., Cole, P. L., Contalbrigo, M., Costantini, G., Crede, V., Dashyan, N., De Vita, R., Defurne, M., Deur, A., Diehl, S., Djalali, C., Dupre, R., Ehrhart, M., Alaoui, A. El, Fassi, L. El, Elouadrhiri, L., Fegan, S., Filippi, A., Gavalian, G., Ghandilyan, Y., Gilfoyle, G. P., Girod, F. X., Glazier, D. I., Golubenko, A. A., Gothe, R. W., Gotra, Y., Griffioen, K. A., Hafidi, K., Hakobyan, H., Hattawy, M., Hauenstein, F., Hayward, T. B., Hobart, A., Holtrop, M., Ilieva, Y., Ireland, D. G., Isupov, E. L., Jo, H. S., Joo, K., Keller, D., Khanal, A., Kim, A., Kim, W., Klimenko, V., Kripko, A., Kubarovsky, V., Leali, M., Lee, S., Lenisa, P., Livingston, K., MacGregor, I. J. D., Marchand, D., Marsicano, L., Mascagna, V., Mayer, M., McKinnon, B., Migliorati, S., Mineeva, T., Mirazita, M., Montgomery, R. A., Camacho, C. Munoz, Nadel-Turonski, P., Neupane, K., Newton, J., Niccolai, S., Osipenko, M., Pandey, P., Paolone, M., Pappalardo, L. L., Paremuzyan, R., Pasyuk, E., Paul, S. J., Pilleux, N., Pogorelko, O., Price, J. W., Prok, Y., Raue, B. A., Reed, T., Ripani, M., Ritman, J., Rizzo, A., Rossi, P., Sabatie, F., Salgado, C., Schmidt, A., Sharabian, Y. G., Shirokov, E. V., Shrestha, U., Simmerling, P., Sokhan, D., Sparveris, N., Stepanyan, S., Strakovsky, I. I., Strauch, S., Tyler, N., Tyson, R., Ungaro, M., Vallarino, S., Venturelli, L., Voskanyan, H., Voutier, E., Watts, D. P., Wei, K., Wei, X., Wishart, R., Wood, M. H., Yale, B., Zachariou, N., Zhang, J., and Ziegler, V.

Subjects
Nuclear Experiment
Abstract

Beam-recoil transferred polarizations for the exclusive electroproduction of $K^+\Lambda$ and $K^+\Sigma^0$ final states from an unpolarized proton target have been measured using the CLAS12 spectrometer at Jefferson Laboratory. The measurements at beam energies of 6.535~GeV and 7.546~GeV span the range of four-momentum transfer $Q^2$ from 0.3 to 4.5~GeV$^2$ and invariant energy $W$ from 1.6 to 2.4~GeV, while covering the full center-of-mass angular range of the $K^+$. These new data extend the existing hyperon polarization data from CLAS in a similar kinematic range but from a significantly larger dataset. They represent an important addition to the world data, allowing for better exploration of the reaction mechanism in strangeness production processes, for further understanding of the spectrum and structure of excited nucleon states, and for improved insight into the strong interaction in the regime of non-perturbative dynamics., Comment: 25 pages, 22 figures, 4 tables

Published
2022
Full Text
View/download PDF

25. Polarized Structure Function $\sigma_{LT'}$ from $\pi^0 p$ Electroproduction Data in the Resonance Region at $0.4$ GeV$^2 < Q^2 < 1.0$ GeV$^2$

Author

Isupov, E. L., Burkert, V. D., Golubenko, A. A., Joo, K., Markov, N. S., Mokeev, V. I., Smith, L. C., Armstrong, W. R., Atac, H., Avakian, H., Baltzell, N. A., Barion, L., Battaglieri, M., Bedlinskiy, I., Benmokhtar, F., Bianconi, A., Biondo, L., Biselli, A. S., Bondi, M., Bossù, F., Briscoe, W. J., Brooks, W. K., Bulumulla, D., Capobianco, R. A., Carman, D. S., Carvajal, J. C., Chatagnon, P., Chesnokov, V., Ciullo, G., Cole, P. L., Clary, B. A., Contalbrigo, M., Costantini, G., D'Angelo, A., Dashyan, N., De Vita, R., Defurne, M., Deur, A., Diehl, S., Djalali, C., Dupre, R., Egiyan, H., Alaoui, A. El, Fassi, L. El, Elouadrhiri, L., Eugenio, P., Fegan, S., Filippi, A., Gavalian, G., Gilfoyle, G. P., Glazier, D. I., Gothe, R. W., Griffioen, K. A., Guidal, M., Guo, L., Hafidi, K., Hakobyan, H., Hattawy, M., Hayward, T. B., Heddle, D., Hicks, K., Hobart, A., Holtrop, M., Illari, I., Ireland, D. G., Jenkins, D., Jo, H. S., Keller, D., Khanal, A., Khandaker, M., Kim, A., Kim, W., Klein, F. J., Klimenko, V., Kripko, A., Kubarovsky, V., Lagerquist, V., Lanza, L., Leali, M., Lenisa, P., Livingston, K., MacGregor, I. J. D., Marchand, D., Marsicano, L., Mascagna, V., McKinnon, B., Meziani, Z. E., Migliorati, S., Mineeva, T., Mirazita, M., Camacho, C. Munoz, Nadel-Turonski, P., Neupane, K., Niccolai, S., O'Connell, T., Osipenko, M., Pandey, P., Paolone, M., Pappalardo, L. L., Paremuzyan, R., Pasyuk, E., Paul, S. J., Phelps, W., Pilleux, N., Pogorelko, O., Poudel, J., Price, J. W., Prok, Y., Raue, B. A., Reed, T., Ripani, M., Ritman, J., Rowley, J., Sabatié, F., Salgado, C., Schmidt, A., Schumacher, R. A., Sharabian, Y. G., Shirokov, E. V., Shrestha, U., Simmerling, P., Sokhan, D., Sparveris, N., Stepanyan, S., Strakovsky, I. I., Strauch, S., Tan, J. A., Tyson, R., Ungaro, M., Vallarino, S., Venturelli, L., Voskanyan, H., Voutier, E., Watts, D., Wei, K., Wei, X., Wood, M. H., Yale, B., Zachariou, N., Zhang, J., and Ziegler, V.

Subjects
Nuclear Experiment
Abstract

The first results on the $\sigma_{LT'}$ structure function in exclusive $\pi^0p$ electroproduction at invariant masses of the final state of 1.5 GeV $<$ $W$ $<$ 1.8 GeV and in the range of photon virtualities 0.4 GeV$^2 < Q^2 < 1.0$ GeV$^2$ were obtained from data on beam spin asymmetries and differential cross sections measured with the CLAS detector at Jefferson Lab. The Legendre moments determined from the $\sigma_{LT'}$ structure function have demonstrated sensitivity to the contributions from the nucleon resonances in the second and third resonance regions. These new data on the beam spin asymmetries in $\pi^0p$ electroproduction extend the opportunities for the extraction of the nucleon resonance electroexcitation amplitudes in the mass range above 1.6 GeV., Comment: 7 pages, 3 figures

Published
2021
Full Text
View/download PDF

26. GlycoGrip: Cell Surface-Inspired Universal Sensor for Betacoronaviruses

Author

Kim, Sang Hoon, Kearns, Fiona L, Rosenfeld, Mia A, Casalino, Lorenzo, Papanikolas, Micah J, Simmerling, Carlos, Amaro, Rommie E, and Freeman, Ronit

Subjects
Vaccine Related, Emerging Infectious Diseases, Prevention, Biodefense, Infectious Diseases, Lung, Infection, Chemical Sciences
Abstract

Inspired by the role of cell-surface glycoproteins as coreceptors for pathogens, we report the development of GlycoGrip: a glycopolymer-based lateral flow assay for detecting SARS-CoV-2 and its variants. GlycoGrip utilizes glycopolymers for primary capture and antispike antibodies labeled with gold nanoparticles for signal-generating detection. A lock-step integration between experiment and computation has enabled efficient optimization of GlycoGrip test strips which can selectively, sensitively, and rapidly detect SARS-CoV-2 and its variants in biofluids. Employing the power of the glycocalyx in a diagnostic assay has distinct advantages over conventional immunoassays as glycopolymers can bind to antigens in a multivalent capacity and are highly adaptable for mutated strains. As new variants of SARS-CoV-2 are identified, GlycoGrip will serve as a highly reconfigurable biosensor for their detection. Additionally, via extensive ensemble-based docking simulations which incorporate protein and glycan motion, we have elucidated important clues as to how heparan sulfate and other glycocalyx components may bind the spike glycoprotein during SARS-CoV-2 host-cell infection. GlycoGrip is a promising and generalizable alternative to costly, labor-intensive RT-PCR, and we envision it will be broadly useful, including for rural or low-income populations that are historically undertested and under-reported in infection statistics.

Published
2022

27. Multidimensional, high precision measurements of beam single spin asymmetries in semi-inclusive $\pi^{+}$ electroproduction off protons in the valence region

Author

Diehl, S., Kim, A., Angelini, G., Joo, K., Adhikari, S., Amaryan, M., Arratia, M., Atac, H., Avakian, H., Gayoso, C. Ayerbe, Baltzell, N. A., Barion, L., Bastami, S., Battaglieri, M., Bedlinskiy, I., Benmokhtar, F., Bianconi, A., Biselli, A. S., Bondi, M., Bossu, F., Boiarinov, S., Brinkmann, K. -T., Briscoe, W. J., Brooks, W., Bulumulla, D., Burkert, V. D., Carman, D. S., Carvajal, J. C., Celentano, A., Chatagnon, P., Chetry, T., Ciullo, G., Clark, L., Clary, B. A., Cole, P. L., Contalbrigo, M., Costantini, G., Crede, V., D'Angelo, A., Dashyan, N., De Vita, R., Defurne, M., Deur, A., Dilks, C., Djalali, C., Dugger, M., Dupre, R., Ehrhart, M., Alaoui, A. El, Fassi, L. El, Elouadrhiri, L., Fegan, S., Filippi, A., Forest, T., Gavalian, G., Gilfoyle, G. P., Girod, F. X., Glazier, D. I., Golubenko, A. A., Gothe, R. W., Gotra, Y., Griffioen, K. A., Guidal, M., Hafidi, K., Hakobyan, H., Hattawy, M., Hayward, T. B., Heddle, D., Hicks, K., Hobart, A., Holtrop, M., Hyde, C. E., Ireland, D. G., Isupov, E. L., Jo, H. S., Johnston, R., Joosten, S., Keller, D., Khachatryan, M., Khanal, A., Kim, W., Kripko, A., Kubarovsky, V., Kuhn, S. E., Lanza, L., Leali, M., Lee, S., Lenisa, P., Livingston, K., Lu, Z., MacGregor, I. J. D., Marchand, D., Markov, N., Marsicano, L., Mascagna, V., McKinnon, B., Meziani, Z. E., Milner, R. G., Mineeva, T., Mirazita, M., Mokeev, V., Moran, P., Movsisyan, A., Camacho, C. Munoz, Nadel-Turonski, P., Naidoo, P., Neupane, K., Niccolai, S., Niculescu, G., O'Connell, T. R., Osipenko, M., Paolone, M., Pappalardo, L. L., Paremuzyan, R., Pasyuk, E., Phelps, W., Pogorelko, O., Prok, Y., Prokudin, A., Raue, B. A., Ripani, M., Ritman, J., Rizzo, A., Roberts, C. D., Rossi, P., Rowley, J., Sabatie, F., Salgado, C., Schmidt, A., Segarra, E. P., Sharabian, Y. G., Shrestha, U., Simmerling, P., Sokhan, D., Soto, O., Sparveris, N., Stepanyan, S., Stoler, P., Strakovsky, I. I., Strauch, S., Tezgin, K., Thornton, A., Tyler, N., Tyson, R., Ungaro, M., Venturelli, L., Voskanyan, H., Vossen, A., Voutier, E., Watts, D. P., Wei, K., Wei, X., Xu, S. -S., Yale, B., Zachariou, N., and Zhang, J.

Subjects
High Energy Physics - Experiment
Abstract

High precision measurements of the polarized electron beam-spin asymmetry in semi-inclusive deep inelastic scattering (SIDIS) from the proton have been performed using a 10.6~GeV incident electron beam and the CLAS12 spectrometer at Jefferson Lab. We report here a high precision multidimensional study of single $\pi^{+}$ SIDIS data over a large kinematic range in Bjorken x, fractional energy and transverse momentum of the hadron as well as photon virtualities $Q^{2}$ ranging from $1-7\,$GeV$^{2}$. In particular, the structure function ratio $F^{\sin\phi}_{LU}/F_{UU}$ has been determined, where $F^{\sin\phi}_{LU}$ is a twist-3 quantity that can reveal novel aspects of emergent hadron mass and quark-gluon correlations within the nucleon. The data's impact on the evolving understanding of the underlying reaction mechanisms and their kinematic variation is explored using theoretical models for the different contributing transverse momentum dependent parton distribution functions.

Published
2021
Full Text
View/download PDF

28. AI-driven multiscale simulations illuminate mechanisms of SARS-CoV-2 spike dynamics

Author

Casalino, Lorenzo, Dommer, Abigail C, Gaieb, Zied, Barros, Emilia P, Sztain, Terra, Ahn, Surl-Hee, Trifan, Anda, Brace, Alexander, Bogetti, Anthony T, Clyde, Austin, Ma, Heng, Lee, Hyungro, Turilli, Matteo, Khalid, Syma, Chong, Lillian T, Simmerling, Carlos, Hardy, David J, Maia, Julio DC, Phillips, James C, Kurth, Thorsten, Stern, Abraham C, Huang, Lei, McCalpin, John D, Tatineni, Mahidhar, Gibbs, Tom, Stone, John E, Jha, Shantenu, Ramanathan, Arvind, and Amaro, Rommie E

Subjects
Vaccine Related, Biodefense, Infectious Diseases, Prevention, Lung, Emerging Infectious Diseases, Infection, Good Health and Well Being, Molecular dynamics, deep learning, multiscale simulation, weighted ensemble, computational virology, SARS-CoV-2, COVID19, HPC, GPU, AI, Distributed Computing
Abstract

We develop a generalizable AI-driven workflow that leverages heterogeneous HPC resources to explore the time-dependent dynamics of molecular systems. We use this workflow to investigate the mechanisms of infectivity of the SARS-CoV-2 spike protein, the main viral infection machinery. Our workflow enables more efficient investigation of spike dynamics in a variety of complex environments, including within a complete SARS-CoV-2 viral envelope simulation, which contains 305 million atoms and shows strong scaling on ORNL Summit using NAMD. We present several novel scientific discoveries, including the elucidation of the spike’s full glycan shield, the role of spike glycans in modulating the infectivity of the virus, and the characterization of the flexible interactions between the spike and the human ACE2 receptor. We also demonstrate how AI can accelerate conformational sampling across different systems and pave the way for the future application of such methods to additional studies in SARS-CoV-2 and other molecular systems.

Published
2021

29. Quantitative Analysis of Protein Unfolded State Energetics: Experimental and Computational Studies Demonstrate That Non-Native Side-Chain Interactions Stabilize Local Native Backbone Structure

Author

Zou, Junjie, Xiao, Shifeng, Simmerling, Carlos, and Raleigh, Daniel P

Subjects
Chemical Sciences, Theoretical and Computational Chemistry, Affordable and Clean Energy, Protein Conformation, Protein Denaturation, Protein Folding, Proteins, Thermodynamics, Physical Sciences, Engineering, Chemical sciences, Physical sciences
Abstract

Proteins fold on relatively smooth free energy landscapes which are biased toward the native state, but even simple topologies which fold rapidly can experience roughness on their free energy landscape. The details of these interactions are difficult to elucidate experimentally. Closely related to the problem of deciphering the details of the free energy landscape is the problem of defining the interactions in the denatured state ensemble (DSE) which is populated under native conditions, that is, under conditions where the native state is stable. The DSE of many proteins deviates from random coil models, but quantifying and defining the energetics of the transiently populated interactions in this ensemble is extremely challenging. Characterization of the DSE of proteins which fold to compact structures is also relevant to studies of intrinsically disordered proteins (IDPs) since interactions in the dynamic ensemble populated by IDPs can modulate their behavior. Here we show how experimental thermodynamic and pKa measurements can be combined with computational thermodynamic integration to quantify interactions in the DSE. We show that non-native side chain interactions can stabilize native backbone structure in the DSE and demonstrate that that even rapidly folding proteins can form energetically significant non-native interactions in their DSE. As an example, we characterize a non-native salt bridge that stabilizes local native backbone structure in the DSE of a widely studied fast-folding protein, the villin headpiece helical domain. The combined computational experimental approach is applicable to other protein unfolded states and provides insight that is impossible to obtain with either method alone.

Published
2021

30. The flexibility of ACE2 in the context of SARS-CoV-2 infection

Author

Barros, Emilia P, Casalino, Lorenzo, Gaieb, Zied, Dommer, Abigail C, Wang, Yuzhang, Fallon, Lucy, Raguette, Lauren, Belfon, Kellon, Simmerling, Carlos, and Amaro, Rommie E

Subjects
Pneumonia, Vaccine Related, Infectious Diseases, Lung, Pneumonia & Influenza, Prevention, Emerging Infectious Diseases, 2.1 Biological and endogenous factors, Aetiology, Infection, Good Health and Well Being, Angiotensin-Converting Enzyme 2, COVID-19, Humans, Molecular Dynamics Simulation, Protein Multimerization, SARS-CoV-2, Physical Sciences, Chemical Sciences, Biological Sciences, Biophysics
Abstract

The coronavirus disease 2019 (COVID-19) pandemic has swept over the world in the past months, causing significant loss of life and consequences to human health. Although numerous drug and vaccine development efforts are underway, there are many outstanding questions on the mechanism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral association to angiotensin-converting enzyme 2 (ACE2), its main host receptor, and host cell entry. Structural and biophysical studies indicate some degree of flexibility in the viral extracellular spike glycoprotein and at the receptor-binding domain (RBD)-receptor interface, suggesting a role in infection. Here, we perform explicitly solvated, all-atom, molecular dynamics simulations of the glycosylated, full-length, membrane-bound ACE2 receptor in both an apo and spike RBD-bound state to probe the intrinsic dynamics of the ACE2 receptor in the context of the cell surface. A large degree of fluctuation in the full-length structure is observed, indicating hinge bending motions at the linker region connecting the head to the transmembrane helix while still not disrupting the ACE2 homodimer or ACE2-RBD interfaces. This flexibility translates into an ensemble of ACE2 homodimer conformations that could sterically accommodate binding of the spike trimer to more than one ACE2 homodimer and suggests a mechanical contribution of the host receptor toward the large spike conformational changes required for cell fusion. This work presents further structural and functional insights into the role of ACE2 in viral infection that can potentially be exploited for the rational design of effective SARS-CoV-2 therapeutics.

Published
2021

31. Protein storytelling through physics

Author

Brini, Emiliano, Simmerling, Carlos, and Dill, Ken

Subjects
Angiotensin-Converting Enzyme 2, COVID-19, Computer Simulation, Humans, Models, Molecular, Protein Domains, Proteins, Spike Glycoprotein, Coronavirus, General Science & Technology
Abstract

Every protein has a story-how it folds, what it binds, its biological actions, and how it misbehaves in aging or disease. Stories are often inferred from a protein's shape (i.e., its structure). But increasingly, stories are told using computational molecular physics (CMP). CMP is rooted in the principled physics of driving forces and reveals granular detail of conformational populations in space and time. Recent advances are accessing longer time scales, larger actions, and blind testing, enabling more of biology's stories to be told in the language of atomistic physics.

Published
2020

32. Dissecting the Energetics of Intrinsically Disordered Proteins via a Hybrid Experimental and Computational Approach

Author

Zou, Junjie, Simmerling, Carlos, and Raleigh, Daniel P

Subjects
Rare Diseases, Networking and Information Technology R&D (NITRD), Genetics, Good Health and Well Being, Intrinsically Disordered Proteins, Molecular Dynamics Simulation, Thermodynamics, Physical Sciences, Chemical Sciences, Engineering
Abstract

Intrinsically disordered proteins (IDPs) play important roles in biology, but little is known about the energetics of their inter-residue interactions. Methods that have been successfully applied to analyze the energetics of globular proteins are not applicable to the fluctuating partially ordered ensembles populated by IDPs. A combined computational experimental strategy is introduced for analyzing the energetic role of individual residues in the free state of IDPs. The approach combines experimental measurements of the binding of wild-type and mutant IDPs to their partners with alchemical free energy calculations of the structured complexes. These data allow quantitative information to be deduced about the free state via a thermodynamic cycle. The approach is validated by the analysis of the effects of mutations upon the binding free energy of the ovomucoid inhibitor third binding domain to its partners and is applied to the C-terminal domain of the measles virus nucleoprotein, a 125-residue IDP involved in the RNA transcription and replication of measles virus. The analysis reveals significant inter-residue interactions in the unbound IDP and suggests a biological role for them. The work demonstrates that advances in force fields and computational hardware have now led to the point where it is possible to develop methods, which integrate experimental and computational techniques to reveal insights that cannot be studied using either technique alone.

Published
2019

33. Laguerre-Intersection Method for Implicit Solvation

Author

Hummel, Michelle Hatch, Yu, Bihua, Simmerling, Carlos, and Coutsias, Evangelos A.

Subjects
Computer Science - Computational Geometry, Mathematics - Metric Geometry
Abstract

Laguerre tessellations of macromolecules capture properties such as molecular interface surfaces, volumes and cavities. Explicit solvent molecular dynamics simulations of a macromolecule are slow as the number of solvent atoms considered typically increases by order of magnitude. Implicit methods model the solvent via continuous corrections to the force field based on estimates of the solvent exposed surface areas of individual atoms, gaining speed at the expense of accuracy. However, Laguerre cells of exterior atoms tend to be overly large or unbounded. Our method, the Laguerre-Intersection method, caps cells in a physically accurate manner by considering the intersection of the space-filling diagram with the Laguerre tessellation. This method optimizes an adjustable parameter, the weight, to ensure the areas and volumes of capped cells exposed to solvent are as close as possible, on average, to those computed from equilibrated explicit solvent simulations. The contact planes are radical planes, meaning that as the solvent weight is varied, cells remain constant. We test the consistency of our model using a high-quality trajectory of HIV-protease, a dimer with flexible loops and open-close transitions. We also compare our results with interval-arithmetic Gauss-Bonnet based method. Optimal solvent parameters quickly converge, which we use to illustrate the increased accuracy of the Laguerre-Intersection method over two recently proposed methods as compared to the explicit model., Comment: 39 pages

Published
2017

37. Experimental and Computational Analysis of Protein Stabilization by Gly-to‑d‑Ala Substitution: A Convolution of Native State and Unfolded State Effects

Author

Zou, Junjie, Song, Benben, Simmerling, Carlos, and Raleigh, Daniel

Subjects
Alanine, Algorithms, Animals, Bacterial Proteins, Chickens, Glycation End Products, Advanced, Glycine, Homeodomain Proteins, Microfilament Proteins, Models, Molecular, Molecular Dynamics Simulation, Protein Stability, Protein Unfolding, Serum Albumin, Thermodynamics, Transcription Factors, Glycated Serum Albumin, Chemical Sciences, General Chemistry
Abstract

The rational and predictable enhancement of protein stability is an important goal in protein design. Most efforts target the folded state, however stability is the free energy difference between the folded and unfolded states thus both are suitable targets. Strategies directed at the unfolded state usually seek to decrease chain entropy by introducing cross-links or by replacing glycines. Cross-linking has led to mixed results. Replacement of glycine with an l-amino acid, while reducing the entropy of the unfolded state, can introduce unfavorable steric interactions in the folded state, since glycine is often found in conformations that require a positive φ angle such as helical C-capping motifs or type I' and II″ β-turns. l-Amino acids are strongly disfavored in these conformations, but d-amino acids are not. However, there are few reported examples and conflicting results have been obtained when glycines are replaced with d-Ala. We critically examine the effect of Gly-to-d-Ala substitutions on protein stability using experimental approaches together with molecular dynamics simulations and free energy calculations. The data, together with a survey of high resolution structures, show that the vast majority of proteins can be stabilized by substitution of C-capping glycines with d-Ala. Sites suitable for substitutions can be identified via sequence alignment with a high degree of success. Steric clashes in the native state due to the new side chain are rarely observed, but are likely responsible for the destabilizing or null effect observed for the small subset of Gly-to-d-Ala substitutions which are not stabilizing. Changes in backbone solvation play less of a role. Favorable candidates for d-Ala substitution can be identified using a rapid algorithm based on molecular mechanics.

Published
2016

38. Advances in free-energy-based simulations of protein folding and ligand binding

Author

Perez, Alberto, Morrone, Joseph A, Simmerling, Carlos, and Dill, Ken A

Subjects
Biochemistry and Cell Biology, Biological Sciences, Generic health relevance, Humans, Ligands, Molecular Dynamics Simulation, Protein Binding, Protein Conformation, Protein Folding, Proteins, Medicinal and Biomolecular Chemistry, Biophysics, Biochemistry and cell biology
Abstract

Free-energy-based simulations are increasingly providing the narratives about the structures, dynamics and biological mechanisms that constitute the fabric of protein science. Here, we review two recent successes. It is becoming practical: first, to fold small proteins with free-energy methods without knowing substructures and second, to compute ligand-protein binding affinities, not just their binding poses. Over the past 40 years, the timescales that can be simulated by atomistic MD are doubling every 1.3 years--which is faster than Moore's law. Thus, these advances are not simply due to the availability of faster computers. Force fields, solvation models and simulation methodology have kept pace with computing advancements, and are now quite good. At the tip of the spear recently are GPU-based computing, improved fast-solvation methods, continued advances in force fields, and conformational sampling methods that harness external information.

Published
2016

40. Grid-Based Backbone Correction to the ff12SB Protein Force Field for Implicit-Solvent Simulations

Author

Perez, Alberto, MacCallum, Justin L, Brini, Emiliano, Simmerling, Carlos, and Dill, Ken A

Subjects
Bioengineering, Molecular Dynamics Simulation, Protein Folding, Proteins, Solvents, Theoretical and Computational Chemistry, Biochemistry and Cell Biology, Computer Software, Chemical Physics
Abstract

Force fields, such as Amber's ff12SB, can be fairly accurate models of the physical forces in proteins and other biomolecules. When coupled with accurate solvation models, force fields are able to bring insight into the conformational preferences, transitions, pathways, and free energies for these biomolecules. When computational speed/cost matters, implicit solvent is often used but at the cost of accuracy. We present an empirical grid-like correction term, in the spirit of cMAPs, to the combination of the ff12SB protein force field and the GBneck2 implicit-solvent model. Ff12SB-cMAP is parametrized on experimental helicity data. We provide validation on a set of peptides and proteins. Ff12SB-cMAP successfully improves the secondary structure biases observed in ff12SB + Gbneck2. Ff12SB-cMAP can be downloaded ( https://github.com/laufercenter/Amap.git ) and used within the Amber package. It can improve the agreement of force fields + implicit solvent with experiments.

Published
2015

41. Accurately Modeling RNA Stem-Loops in an Implicit Solvent Environment

Author

Linzer, Jason T., Aminov, Ethan, Abdullah, Aalim S., Kirkup, Colleen E., Diaz Ventura, Rebeca I., Bijoor, Vinay R., Jung, Jiyun, Huang, Sophie, Tse, Chi Gee, Álvarez Toucet, Emily, Onghai, Hugo P., Ghosh, Arghya P., Grodzki, Alex C., Haines, Emilee R., Iyer, Aditya S., Khalil, Mark K., Leong, Alexander P., Neuhaus, Michael A., Park, Joseph, Shahid, Asir, Xie, Matthew, Ziembicki, Jan M., Simmerling, Carlos, and Nagan, Maria C.

Abstract

Ribonucleic acid (RNA) molecules can adopt a variety of secondary and tertiary structures in solution, with stem-loops being one of the more common motifs. Here, we present a systematic analysis of 15 RNA stem-loop sequences simulated with molecular dynamics simulations in an implicit solvent environment. Analysis of RNA cluster ensembles showed that the stem-loop structures can generally adopt the A-form RNA in the stem region. Loop structures are more sensitive, and experimental structures could only be reproduced with modification of CH···O interactions in the force field, combined with an implicit solvent nonpolar correction to better model base stacking interactions. Accurately modeling RNA with current atomistic physics-based models remains challenging, but the RNA systems studied herein may provide a useful benchmark set for testing other RNA modeling methods in the future.

Published
2024
Full Text
View/download PDF

45. k-Means

Author

Chen, Lexin, Roe, Daniel R., Kochert, Matthew, Simmerling, Carlos, and Miranda-Quintana, Ramón Alain

Abstract

One of the key challenges of k-means clustering is the seed selection or the initial centroid estimation since the clustering result depends heavily on this choice. Alternatives such as k-means++ have mitigated this limitation by estimating the centroids using an empirical probability distribution. However, with high-dimensional and complex data sets such as those obtained from molecular simulation, k-means++ fails to partition the data in an optimal manner. Furthermore, stochastic elements in all flavors of k-means++ will lead to a lack of reproducibility. K-means N-Ary Natural Initiation (NANI) is presented as an alternative to tackle this challenge by using efficient n-ary comparisons to both identify high-density regions in the data and select a diverse set of initial conformations. Centroids generated from NANI are not only representative of the data and different from one another, helping k-means to partition the data accurately, but also deterministic, providing consistent cluster populations across replicates. From peptide and protein folding molecular simulations, NANI was able to create compact and well-separated clusters as well as accurately find the metastable states that agree with the literature. NANI can cluster diverse data sets and be used as a standalone tool or as part of our MDANCE clustering package.

Published
2024
Full Text
View/download PDF

47. Detector requirements and simulation results for the EIC exclusive, diffractive and tagging physics program using the ECCE detector concept

Author

A. Bylinkin, C.T. Dean, S. Fegan, D. Gangadharan, K. Gates, S.J.D. Kay, I. Korover, W.B. Li, X. Li, R. Montgomery, D. Nguyen, G. Penman, J.R. Pybus, N. Santiesteban, S. Shimizu, R. Trotta, A. Usman, M.D. Baker, J. Frantz, D.I. Glazier, D.W. Higinbotham, T. Horn, J. Huang, G.M. Huber, R. Reed, J. Roche, A. Schmidt, P. Steinberg, J. Stevens, Y. Goto, C. Munoz Camacho, M. Murray, Z. Papandreou, W. Zha, J.K. Adkins, Y. Akiba, A. Albataineh, M. Amaryan, I.C. Arsene, C. Ayerbe Gayoso, J. Bae, X. Bai, M. Bashkanov, R. Bellwied, F. Benmokhtar, V. Berdnikov, J.C. Bernauer, F. Bock, W. Boeglin, M. Borysova, E. Brash, P. Brindza, W.J. Briscoe, M. Brooks, S. Bueltmann, M.H.S. Bukhari, R. Capobianco, W.-C. Chang, Y. Cheon, K. Chen, K.-F. Chen, K.-Y. Cheng, M. Chiu, T. Chujo, Z. Citron, E. Cline, E. Cohen, T. Cormier, Y. Corrales Morales, C. Cotton, J. Crafts, C. Crawford, S. Creekmore, C. Cuevas, J. Cunningham, G. David, M. Demarteau, S. Diehl, N. Doshita, R. Dupré, J.M. Durham, R. Dzhygadlo, R. Ehlers, L. El Fassi, A. Emmert, R. Ent, C. Fanelli, R. Fatemi, M. Finger, M. Friedman, I. Friscic, S. Gardner, F. Geurts, R. Gilman, E. Glimos, N. Grau, S.V. Greene, A.Q. Guo, L. Guo, S.K. Ha, J. Haggerty, T. Hayward, X. He, O. Hen, M. Hoballah, A. Hoghmrtsyan, P.-h.J. Hsu, A. Hutson, K.Y. Hwang, C.E. Hyde, M. Inaba, T. Iwata, H.S. Jo, K. Joo, N. Kalantarians, G. Kalicy, K. Kawade, A. Kim, B. Kim, C. Kim, M. Kim, Y. Kim, E. Kistenev, V. Klimenko, S.H. Ko, W. Korsch, G. Krintiras, S. Kuhn, C.-M. Kuo, T. Kutz, J. Lajoie, D. Lawrence, S. Lebedev, H. Lee, J.S.H. Lee, S.W. Lee, Y.-J. Lee, W. Li, Y.T. Liang, S. Lim, C.-h. Lin, D.X. Lin, K. Liu, M.X. Liu, K. Livingston, N. Liyanage, W.J. Llope, C. Loizides, E. Long, R.-S. Lu, Z. Lu, W. Lynch, S. Mantry, D. Marchand, M. Marcisovsky, C. Markert, P. Markowitz, H. Marukyan, P. McGaughey, M. Mihovilovic, R.G. Milner, A. Milov, Y. Miyachi, A. Mkrtchyan, P. Monaghan, D. Morrison, A. Movsisyan, H. Mkrtchyan, K. Nagai, J. Nagle, I. Nakagawa, C. Nattrass, S. Niccolai, R. Nouicer, G. Nukazuka, M. Nycz, V.A. Okorokov, S. Orešić, J.D. Osborn, C. O’Shaughnessy, S. Paganis, S.F. Pate, M. Patel, C. Paus, M.G. Perdekamp, D.V. Perepelitsa, H. Periera da Costa, K. Peters, W. Phelps, E. Piasetzky, C. Pinkenburg, I. Prochazka, T. Protzman, M.L. Purschke, J. Putschke, R. Rajput-Ghoshal, J. Rasson, B. Raue, K.F. Read, K. Røed, J. Reinhold, E.L. Renner, J. Richards, C. Riedl, T. Rinn, G.M. Roland, G. Ron, M. Rosati, C. Royon, J. Ryu, S. Salur, R. Santos, M. Sarsour, J. Schambach, N. Schmidt, C. Schwarz, J. Schwiening, R. Seidl, A. Sickles, P. Simmerling, S. Sirca, D. Sharma, Z. Shi, T.-A. Shibata, C.-W. Shih, U. Shrestha, K. Slifer, K. Smith, D. Sokhan, R. Soltz, W. Sondheim, J. Song, I.I. Strakovsky, P. Stepanov, J. Strube, P. Sun, X. Sun, K. Suresh, V. Tadevosyan, W.-C. Tang, S. Tapia Araya, S. Tarafdar, L. Teodorescu, D. Thomas, A. Timmins, L. Tomasek, N. Trotta, T.S. Tveter, E. Umaka, H.W. van Hecke, C. Van Hulse, J. Velkovska, E. Voutier, P.K. Wang, Q. Wang, Y. Wang, D.P. Watts, N. Wickramaarachchi, L. Weinstein, M. Williams, C.-P. Wong, L. Wood, M.H. Wood, C. Woody, B. Wyslouch, Z. Xiao, Y. Yamazaki, Y. Yang, Z. Ye, H.D. Yoo, M. Yurov, N. Zachariou, W.A. Zajc, J.-L. Zhang, J.-X. Zhang, Y. Zhang, Y.-X. Zhao, X. Zheng, P. Zhuang, HEP, INSPIRE, Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay

Subjects
Nuclear and High Energy Physics, Physics - Instrumentation and Detectors, detector: performance, [PHYS.NEXP] Physics [physics]/Nuclear Experiment [nucl-ex], nucleon: structure, diffraction, FOS: Physical sciences, tagging, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], ion: beam, Diffractive, exclusive, EIC, Tagging, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Nuclear Experiment (nucl-ex), electron–ion collider, Instrumentation, Nuclear Experiment, detector: design, quark gluon, nucleus, Electron Ion Collider, Instrumentation and Detectors (physics.ins-det), experimental equipment, [PHYS.PHYS.PHYS-INS-DET] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], diffractive, Exclusive, vertex: primary, ECCE, technology: proposed
Abstract

The version of this article on this repository is an arXiv preprint (arXiv:2208.14575v2 [physics.ins-det] Mon, 6 Mar 2023 19:46:42 UTC (39,794 KB)) submitted to Elsevier and is not the final, peer reviewed, corrected article. It is made available under a Creative Commons (CC BY 4.0) Attribution License. This article presents a collection of simulation studies using the ECCE detector concept in the context of the EIC's exclusive, diffractive, and tagging physics program, which aims to further explore the rich quark–gluon structure of nucleons and nuclei. To successfully execute the program, ECCE proposed to utilize the detector system close to the beamline to ensure exclusivity and tag ion beam/fragments for a particular reaction of interest. Preliminary studies confirm the proposed technology and design satisfy the requirements. The projected physics impact results are based on the projected detector performance from the simulation at 10 or 100 fb−1 of integrated luminosity. Additionally, insights related to a potential second EIC detector are documented, which could serve as a guidepost for future development. Office of Nuclear Physics in the Office of Science in the Department of Energy, the National Science Foundation, USA, the Los Alamos National Laboratory Directed Research and Development (LDRD), USA 20200022DR, the Natural Sciences and Engineering Research Council of Canada (NSERC), and the UK Research and Innovation Science and Technology Facilities Council; This research used resources from the Compute and Data Environment for Science (CADES) at the Oak Ridge National Laboratory, which is supported by the Office of Science of the U.S. Department of Energy under Contract No. DE-AC05-00OR22725; Brookhaven National Lab and the Thomas Jefferson National Accelerator Facility which are operated under contracts DE-SC0012704 and DE-AC05-06OR23177 respectively.

Published
2023
Full Text
View/download PDF

48. ECCE sensitivity studies for single hadron transverse single spin asymmetry measurements

Author

R. Seidl, A. Vladimirov, D. Pitonyak, A. Prokudin, J.K. Adkins, Y. Akiba, A. Albataineh, M. Amaryan, I.C. Arsene, C. Ayerbe Gayoso, J. Bae, X. Bai, M.D. Baker, M. Bashkanov, R. Bellwied, F. Benmokhtar, V. Berdnikov, J.C. Bernauer, F. Bock, W. Boeglin, M. Borysova, E. Brash, P. Brindza, W.J. Briscoe, M. Brooks, S. Bueltmann, M.H.S. Bukhari, A. Bylinkin, R. Capobianco, W.-C. Chang, Y. Cheon, K. Chen, K.-F. Chen, K.-Y. Cheng, M. Chiu, T. Chujo, Z. Citron, E. Cline, E. Cohen, T. Cormier, Y. Corrales Morales, C. Cotton, J. Crafts, C. Crawford, S. Creekmore, C. Cuevas, J. Cunningham, G. David, C.T. Dean, M. Demarteau, S. Diehl, N. Doshita, R. Dupré, J.M. Durham, R. Dzhygadlo, R. Ehlers, L. El Fassi, A. Emmert, R. Ent, C. Fanelli, R. Fatemi, S. Fegan, M. Finger, J. Frantz, M. Friedman, I. Friscic, D. Gangadharan, S. Gardner, K. Gates, F. Geurts, R. Gilman, D. Glazier, E. Glimos, Y. Goto, N. Grau, S.V. Greene, A.Q. Guo, L. Guo, S.K. Ha, J. Haggerty, T. Hayward, X. He, O. Hen, D.W. Higinbotham, M. Hoballah, T. Horn, A. Hoghmrtsyan, P.-h.J. Hsu, J. Huang, G. Huber, A. Hutson, K.Y. Hwang, C.E. Hyde, M. Inaba, T. Iwata, H.S. Jo, K. Joo, N. Kalantarians, G. Kalicy, K. Kawade, S.J.D. Kay, A. Kim, B. Kim, C. Kim, M. Kim, Y. Kim, E. Kistenev, V. Klimenko, S.H. Ko, I. Korover, W. Korsch, G. Krintiras, S. Kuhn, C.-M. Kuo, T. Kutz, J. Lajoie, D. Lawrence, S. Lebedev, H. Lee, J.S.H. Lee, S.W. Lee, Y.-J. Lee, W. Li, W.B. Li, X. Li, Y.T. Liang, S. Lim, C.-H. Lin, D.X. Lin, K. Liu, M.X. Liu, K. Livingston, N. Liyanage, W.J. Llope, C. Loizides, E. Long, R.-S. Lu, Z. Lu, W. Lynch, S. Mantry, D. Marchand, M. Marcisovsky, C. Markert, P. Markowitz, H. Marukyan, P. McGaughey, M. Mihovilovic, R.G. Milner, A. Milov, Y. Miyachi, A. Mkrtchyan, P. Monaghan, R. Montgomery, D. Morrison, A. Movsisyan, H. Mkrtchyan, C. Munoz Camacho, M. Murray, K. Nagai, J. Nagle, I. Nakagawa, C. Nattrass, D. Nguyen, S. Niccolai, R. Nouicer, G. Nukazuka, M. Nycz, V.A. Okorokov, S. Orešić, J.D. Osborn, C. O’Shaughnessy, S. Paganis, Z. Papandreou, S.F. Pate, M. Patel, C. Paus, G. Penman, M.G. Perdekamp, D.V. Perepelitsa, H. Periera da Costa, K. Peters, W. Phelps, E. Piasetzky, C. Pinkenburg, I. Prochazka, T. Protzman, M.L. Purschke, J. Putschke, J.R. Pybus, R. Rajput-Ghoshal, J. Rasson, B. Raue, K.F. Read, K. Røed, R. Reed, J. Reinhold, E.L. Renner, J. Richards, C. Riedl, T. Rinn, J. Roche, G.M. Roland, G. Ron, M. Rosati, C. Royon, J. Ryu, S. Salur, N. Santiesteban, R. Santos, M. Sarsour, J. Schambach, A. Schmidt, N. Schmidt, C. Schwarz, J. Schwiening, A. Sickles, P. Simmerling, S. Sirca, D. Sharma, Z. Shi, T.-A. Shibata, C.-W. Shih, S. Shimizu, U. Shrestha, K. Slifer, K. Smith, D. Sokhan, R. Soltz, W. Sondheim, J. Song, I.I. Strakovsky, P. Steinberg, P. Stepanov, J. Stevens, J. Strube, P. Sun, X. Sun, K. Suresh, V. Tadevosyan, W.-C. Tang, S. Tapia Araya, S. Tarafdar, L. Teodorescu, D. Thomas, A. Timmins, L. Tomasek, N. Trotta, R. Trotta, T.S. Tveter, E. Umaka, A. Usman, H.W. van Hecke, C. Van Hulse, J. Velkovska, E. Voutier, P.K. Wang, Q. Wang, Y. Wang, D.P. Watts, N. Wickramaarachchi, L. Weinstein, M. Williams, C.-P. Wong, L. Wood, M.H. Wood, C. Woody, B. Wyslouch, Z. Xiao, Y. Yamazaki, Y. Yang, Z. Ye, H.D. Yoo, M. Yurov, N. Zachariou, W.A. Zajc, W. Zha, J.-L. Zhang, J.-X. Zhang, Y. Zhang, Y.-X. Zhao, X. Zheng, P. Zhuang, Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay

Subjects
transverse spin dependent distribution and fragmentation functions, Nuclear and High Energy Physics, FOS: Physical sciences, lepton: scattering, transverse momentum dependence, hadron: transverse momentum, fragmentation function, x-dependence, High Energy Physics - Experiment, Sivers function, semi-inclusive DIS, High Energy Physics - Experiment (hep-ex), [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], parton, Collins, Instrumentation, transversity, spin: transverse, flavor, deep inelastic scattering: semi-inclusive reaction, positron p: deep inelastic scattering, nucleon: spin: transverse, sensitivity, Transverse spin dependent distribution and fragmentation functions, error: statistical, kinematics, ECCE detector feasibility studies, charge: tensor, numerical calculations: Monte Carlo, Semi-inclusive DIS, spin: asymmetry
Abstract

We performed feasibility studies for various single transverse spin measurements that are related to the Sivers effect, transversity and the tensor charge, and the Collins fragmentation function. The processes studied include semi-inclusive deep inelastic scattering (SIDIS) where single hadrons (pions and kaons) were detected in addition to the scattered DIS lepton. The data were obtained in {\sc pythia}6 and {\sc geant}4 simulated e+p collisions at 18 GeV on 275 GeV, 18 on 100, 10 on 100, and 5 on 41 that use the ECCE detector configuration. Typical DIS kinematics were selected, most notably $Q^2 > 1 $ GeV$^2$, and cover the $x$ range from $10^{-4}$ to $1$. The single spin asymmetries were extracted as a function of $x$ and $Q^2$, as well as the semi-inclusive variables $z$, and $P_T$. They are obtained in azimuthal moments in combinations of the azimuthal angles of the hadron transverse momentum and transverse spin of the nucleon relative to the lepton scattering plane. The initially unpolarized MonteCarlo was re-weighted in the true kinematic variables, hadron types and parton flavors based on global fits of fixed target SIDIS experiments and $e^+e^-$ annihilation data. The expected statistical precision of such measurements is extrapolated to 10 fb$^{-1}$ and potential systematic uncertainties are approximated given the deviations between true and reconstructed yields. The impact on the knowledge of the Sivers functions, transversity and tensor charges, and the Collins function has then been evaluated in the same phenomenological extractions as in the Yellow Report. The impact is found to be comparable to that obtained with the parameterized Yellow Report detector and shows that the ECCE detector configuration can fulfill the physics goals on these quantities., 22 pages, 22 figures, to be submitted to joint ECCE proposal NIM-A volume

Published
2023
Full Text
View/download PDF

49. Alignment of the CLAS12 central hybrid tracker with a Kalman Filter

Author

S.J. Paul, A. Peck, M. Arratia, Y. Gotra, V. Ziegler, R. De Vita, F. Bossù, M. Defurne, H. Atac, C. Ayerbe Gayoso, L. Baashen, N.A. Baltzell, L. Barion, M. Bashkanov, M. Battaglieri, I. Bedlinskiy, B. Benkel, F. Benmokhtar, A. Bianconi, L. Biondo, A.S. Biselli, M. Bondi, S. Boiarinov, K.-Th. Brinkmann, W.J. Briscoe, W.K. Brooks, D. Bulumulla, V.D. Burkert, R. Capobianco, D.S. Carman, J.C. Carvajal, P. Chatagnon, V. Chesnokov, T. Chetry, G. Ciullo, P.L. Cole, G. Costantini, A. D’Angelo, N. Dashyan, A. Deur, S. Diehl, C. Djalali, R. Dupre, A. El Alaoui, L. El Fassi, L. Elouadrhiri, A. Filippi, K. Gates, G. Gavalian, Y. Ghandilyan, G.P. Gilfoyle, A.A. Golubenko, G. Gosta, R.W. Gothe, K. Griffioen, M. Guidal, H. Hakobyan, M. Hattawy, F. Hauenstein, T.B. Hayward, D. Heddle, A. Hobart, M. Holtrop, Y. Ilieva, D.G. Ireland, E.L. Isupov, H.S. Jo, R. Johnston, K. Joo, D. Keller, M. Khachatryan, A. Khanal, A. Kim, W. Kim, V. Klimenko, A. Kripko, L. Lanza, M. Leali, P. Lenisa, X. Li, I.J.D. MacGregor, D. Marchand, L. Marsicano, V. Mascagna, B. McKinnon, C. McLauchlin, S. Migliorati, T. Mineeva, M. Mirazita, V. Mokeev, C. Munoz Camacho, P. Nadel-Turonski, P. Naidoo, K. Neupane, D. Nguyen, S. Niccolai, M. Nicol, G. Niculescu, M. Osipenko, P. Pandey, M. Paolone, R. Paremuzyan, N. Pilleux, O. Pogorelko, M. Pokhrel, J. Poudel, J.W. Price, Y. Prok, T. Reed, M. Ripani, J. Ritman, F. Sabatié, S. Schadmand, A. Schmidt, E.V. Shirokov, U. Shrestha, P. Simmerling, D. Sokhan, N. Sparveris, M. Spreafico, I.I. Strakovsky, S. Strauch, J.A. Tan, R. Tyson, M. Ungaro, S. Vallarino, L. Venturelli, H. Voskanyan, E. Voutier, D.P. Watts, X. Wei, R. Wishart, M.H. Wood, N. Zachariou, Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), and Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)

Subjects
Nuclear and High Energy Physics, data analysis method, Physics - Instrumentation and Detectors, FOS: Physical sciences, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), CLAS, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], ddc:530, tracking detector, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Nuclear Experiment (nucl-ex), numerical calculations, Nuclear Experiment, Instrumentation, Alignment, track data analysis, Settore FIS/04, Detector, Instrumentation and Detectors (physics.ins-det), detector: alignment, Kalman filter, cosmic radiation, semiconductor detector: microstrip, performance
Abstract

International audience; Several factors can contribute to the difficulty of aligning the sensors of tracking detectors, including a large number of modules, multiple types of detector technologies, and non-linear strip patterns on the sensors. The latter two of these three factors apply to the CLAS12 CVT, which is a hybrid detector consisting of planar silicon sensors with non-parallel strips, and cylindrical micromegas sensors with longitudinal and arc-shaped strips located within a 5 T superconducting solenoid. To align this detector, we used the Kalman Alignment Algorithm, which accounts for correlations between the alignment parameters without requiring the time-consuming inversion of large matrices. This is the first time that this algorithm has been adapted for use with hybrid technologies, non-parallel strips, and curved sensors. We present the results for the first alignment of the CLAS12 CVT using straight tracks from cosmic rays and from a target with the magnetic field turned off. After running this procedure, we achieved alignment at the level of l. 967 10μm, and the widths of the residual spectra were greatly reduced. These results attest to the flexibility of this algorithm and its applicability to future use in the CLAS12 CVT and other hybrid or curved trackers, such as those proposed for the future Electron-Ion Collider.

Published
2023
Full Text
View/download PDF

50. Search for e→τ charged lepton flavor violation at the EIC with the ECCE detector

Author

J.-L. Zhang, S. Mantry, J.K. Adkins, Y. Akiba, A. Albataineh, M. Amaryan, I.C. Arsene, C. Ayerbe Gayoso, J. Bae, X. Bai, M.D. Baker, M. Bashkanov, R. Bellwied, F. Benmokhtar, V. Berdnikov, J.C. Bernauer, F. Bock, W. Boeglin, M. Borysova, E. Brash, P. Brindza, W.J. Briscoe, M. Brooks, S. Bueltmann, M.H.S. Bukhari, A. Bylinkin, R. Capobianco, W.-C. Chang, Y. Cheon, K. Chen, K.-F. Chen, K.-Y. Cheng, M. Chiu, T. Chujo, Z. Citron, E. Cline, E. Cohen, T. Cormier, Y. Corrales Morales, C. Cotton, J. Crafts, C. Crawford, S. Creekmore, C. Cuevas, J. Cunningham, G. David, C.T. Dean, M. Demarteau, S. Diehl, N. Doshita, R. Dupré, J.M. Durham, R. Dzhygadlo, R. Ehlers, L. El Fassi, A. Emmert, R. Ent, C. Fanelli, R. Fatemi, S. Fegan, M. Finger, J. Frantz, M. Friedman, I. Friscic, D. Gangadharan, S. Gardner, K. Gates, F. Geurts, R. Gilman, D. Glazier, E. Glimos, Y. Goto, N. Grau, S.V. Greene, A.Q. Guo, L. Guo, S.K. Ha, J. Haggerty, T. Hayward, X. He, O. Hen, D.W. Higinbotham, M. Hoballah, T. Horn, A. Hoghmrtsyan, P.-h.J. Hsu, J. Huang, G. Huber, A. Hutson, K.Y. Hwang, C.E. Hyde, M. Inaba, T. Iwata, H.S. Jo, K. Joo, N. Kalantarians, G. Kalicy, K. Kawade, S.J.D. Kay, A. Kim, B. Kim, C. Kim, M. Kim, Y. Kim, E. Kistenev, V. Klimenko, S.H. Ko, I. Korover, W. Korsch, G. Krintiras, S. Kuhn, C.-M. Kuo, T. Kutz, J. Lajoie, D. Lawrence, S. Lebedev, H. Lee, J.S.H. Lee, S.W. Lee, Y.-J. Lee, W. Li, W.B. Li, X. Li, Y.T. Liang, S. Lim, C.-H. Lin, D.X. Lin, K. Liu, M.X. Liu, K. Livingston, N. Liyanage, W.J. Llope, C. Loizides, E. Long, R.-S. Lu, Z. Lu, W. Lynch, D. Marchand, M. Marcisovsky, C. Markert, P. Markowitz, H. Marukyan, P. McGaughey, M. Mihovilovic, R.G. Milner, A. Milov, Y. Miyachi, A. Mkrtchyan, H. Mkrtchyan, P. Monaghan, R. Montgomery, D. Morrison, A. Movsisyan, C. Munoz Camacho, M. Murray, K. Nagai, J. Nagle, I. Nakagawa, C. Nattrass, D. Nguyen, S. Niccolai, R. Nouicer, G. Nukazuka, M. Nycz, V.A. Okorokov, S. Orešić, J.D. Osborn, C. O’Shaughnessy, S. Paganis, Z. Papandreou, S.F. Pate, M. Patel, C. Paus, G. Penman, M.G. Perdekamp, D.V. Perepelitsa, H. Periera da Costa, K. Peters, W. Phelps, E. Piasetzky, C. Pinkenburg, I. Prochazka, T. Protzman, M.L. Purschke, J. Putschke, J.R. Pybus, R. Rajput-Ghoshal, J. Rasson, B. Raue, K.F. Read, K. Røed, R. Reed, J. Reinhold, E.L. Renner, J. Richards, C. Riedl, T. Rinn, J. Roche, G.M. Roland, G. Ron, M. Rosati, C. Royon, J. Ryu, S. Salur, N. Santiesteban, R. Santos, M. Sarsour, J. Schambach, A. Schmidt, N. Schmidt, C. Schwarz, J. Schwiening, R. Seidl, A. Sickles, P. Simmerling, S. Sirca, D. Sharma, Z. Shi, T.-A. Shibata, C.-W. Shih, S. Shimizu, U. Shrestha, K. Slifer, K. Smith, D. Sokhan, R. Soltz, W. Sondheim, J. Song, I.I. Strakovsky, P. Steinberg, P. Stepanov, J. Stevens, J. Strube, P. Sun, X. Sun, K. Suresh, V. Tadevosyan, W.-C. Tang, S. Tapia Araya, S. Tarafdar, L. Teodorescu, D. Thomas, A. Timmins, L. Tomasek, N. Trotta, R. Trotta, T.S. Tveter, E. Umaka, A. Usman, H.W. van Hecke, C. Van Hulse, J. Velkovska, E. Voutier, P.K. Wang, Q. Wang, Y. Wang, D.P. Watts, N. Wickramaarachchi, L. Weinstein, M. Williams, C.-P. Wong, L. Wood, M.H. Wood, C. Woody, B. Wyslouch, Z. Xiao, Y. Yamazaki, Y. Yang, Z. Ye, H.D. Yoo, M. Yurov, N. Zachariou, W.A. Zajc, W. Zha, J.-X. Zhang, Y. Zhang, Y.-X. Zhao, X. Zheng, and P. Zhuang

Subjects
Nuclear and High Energy Physics, Instrumentation
Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results