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We report about a young male who presented with generalized muscle stiffness, involving the limb, facial, and paraspinal muscles. The stiffness was severe enough to restrict all his daily activities, progressively increased with movements and also produced recurrent falls. This clinical picture resembled one of stiff person syndrome. As he had hypertrophy of calf muscles and generalized muscle tautness he was evaluated for other disorders which can resemble stiff person syndrome. Investigations revealed severe hypothyroidism with thyroid antibodies being elevated. This case is reported to highlight the fact that myopathy as a presenting manifestation of hypothyroidism can simulate stiff person syndrome. It is essential to identify the condition early as it recovers fully with treatment. Our patient responded well to thyroid replacement therapy and was able to lead a normal life.

This article discusses a rare case of bilateral medial medullary infarction, a type of stroke that affects less than 0.5% of all cerebral infarcts. The usual presentation of this condition includes contralateral hemiplegia, loss of vibration sensation, and ipsilateral hypoglossal paralysis. However, the patient in this case had an incomplete syndrome, presenting with giddiness, numbness in the right lower limb, and weakness in the right upper and lower limbs. The MRI revealed bilateral ventral medulla infarction with the characteristic "heart appearance sign." The patient was treated with medication and physiotherapy, and her symptoms improved without respiratory failure. [Extracted from the article]

A case study of a 55‑year‑old male, farmer by occupation, who is nonalcoholic and nonsmoker with no comorbidities was admitted to the emergency department with a history of multiple bee stings and presented with swelling and itching over face and neck. Topics include acute infarct in left frontal, parietal, occipital cortical and subcortical regions with no mass effect; and anaphylaxis causing severe hypotension resulting in decreased cerebral hypoperfusion leading to watershed infarct.