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Liquid argon detectors rely on wavelength shifters for efficient detection of scintillation light. The current standard is tetraphenyl butadiene (TPB), but it is challenging to instrument on a large scale. Poly(ethylene 2,6-naphthalate) (PEN), a polyester easily manufactured as thin sheets, could simplify the coverage of large surfaces with wavelength shifters. Previous measurements have shown that commercial grades of PEN have approximately 50% light conversion efficiency relative to TPB. Encouraged by these results, we conducted a large-scale measurement using $4~m^2$ combined PEN and specular reflector foils in a two-tonne liquid argon dewar to assess its stability over approximately two weeks. This test is crucial for validating PEN as a viable substitute for TPB. The setup used for the measurement of the stability of PEN as a wavelength shifter is described, together with the first results, showing no evidence of performance deterioration over a period of 12 days., Comment: 10 pages, 13 figures

Quantitative and reproducible optical characterization of single quantum emitters is crucial for quantum photonic materials research, yet controlling for experimental conditions remains challenging due to a lack of an established reference standard. We propose nanodiamonds containing single nitrogen vacancy (NV$^{-}$) color centers as reliable, stable and robust sources of single-photon emission. We select 4 potential reference emitter candidates from a study of thousands of NV$^{-}$ centers. Candidates were remeasured at a second laboratory, correlating optical pump power and NV$^{-}$ center emission intensity at saturation in addition to corresponding $g^{(2)}(0)$ values. A reference nanodiamond is demonstrated to control for experimental conditions, with reproducible and reliable single-photon emission, as a model for a new single-photon emitter reference standard.

The large-scale structure of the Universe and its evolution over time contains an abundance of cosmological information. One way to unlock this is by measuring the density and momentum power spectrum from the positions and peculiar velocities of galaxies, and fitting the cosmological parameters from these power spectrum. In this paper, we will explore the cross power spectrum between the density and momentum fields of galaxies. We derive the estimator of the density-momentum cross power spectrum multipoles. The growth rate of the large-scale-structure, $f\sigma_8$ is measured from fitting the combined density monopole, momentum monopole and cross dipole power spectrum. The estimators and models of power spectrum as well as our fitting method have been tested using mock catalogues, and we find that they perform well in recovering the fiducial values of the cosmological parameters of the simulations, and we also find that the errors of the parameters can be largely reduced by including the cross-power spectrum in the fit. We measure the auto-density, auto-momentum and cross power spectrum using the Sloan Digital Sky Survey Data Release 14 peculiar velocity catalogue. The fit result of the growth rate $f\sigma_8$ is $f\sigma_8=0.413^{+0.050}_{-0.058}$ at effective redshift $z_{\mathrm{eff}}=0.073$, and our measurement is consistent with the prediction of the $\Lambda$ Cold Dark Matter cosmological model assuming General Relativity., Comment: 15 pages, 8 figures, 2 tables. Published in ApJ

The relationship between galaxies and their supermassive black holes (SMBHs) is an area of active research. One way to investigate this is to compare parsec-scale jets formed by SMBHs with the projected shape of their kiloparsec-scale host galaxies. We analyse Very Long Baseline Interferometry (VLBI) images of Active Galactic Nuclei (AGN) and optical images of their host galaxies. We compare the inner-jet position angle in VLBI-detected radio sources with the optical shapes of galaxies as measured by several large optical surveys. In total 6273 galaxy-AGN pairs were found. We carefully account for the systematics of the cross-matched sources and find that Dark Energy Spectroscopic Instrument Legacy Imaging Surveys data (DESI LS) is significantly less affected by them. Using DESI LS, with which 5853 galaxy-AGN pairs were cross-matched, we find a weak but significant alignment signal (with a p-value $\leqslant$ 0.01) between the parsec-scale AGN jet and the kpc projected minor axis of the optical host galaxy in sources with measured spectroscopic redshifts. Our results show that the observed source properties are connected over 3 orders of magnitude in scale. This points towards an intimate connection between the SMBH, their host galaxies and their subsequent evolution., Comment: 37 pages, 15 figures, published in Nature Astronomy: https://www.nature.com/articles/s41550-024-02407-4

The recent detection of extended $\gamma$-ray emission around middle-aged pulsars is interpreted as inverse-Compton scattering of ambient photons by electron-positron pairs escaping the pulsar wind nebula, which are confined near the system by unclear mechanisms. This emerging population of $\gamma$-ray sources was first discovered at TeV energies and remains underexplored in the GeV range. To address this, we conducted a systematic search for extended sources along the Galactic plane using 14 years of Fermi-LAT data above 10 GeV, aiming to identify a number of pulsar halo candidates and extend our view to lower energies. The search covered the inner Galactic plane ($\lvert l\rvert\leq$ 100$^{\circ}$, $\lvert b\rvert\leq$ 1$^{\circ}$) and the positions of known TeV sources and bright pulsars, yielding broader astrophysical interest. We found 40 such sources, forming the Second Fermi Galactic Extended Sources Catalog (2FGES), most with 68% containment radii smaller than 1.0$^{\circ}$ and relatively hard spectra with photon indices below 2.5. We assessed detection robustness using field-specific alternative interstellar emission models and by inspecting significance maps. Noting 13 sources previously known as extended in the 4FGL-DR3 catalog and five dubious sources from complex regions, we report 22 newly detected extended sources above 10 GeV. Of these, 13 coincide with H.E.S.S., HAWC, or LHAASO sources; six coincide with bright pulsars (including four also coincident with TeV sources); six are associated with 4FGL point sources only; and one has no association in the scanned catalogs. Notably, six to eight sources may be related to pulsars as classical pulsar wind nebulae or pulsar halos., Comment: 43 pages, 17 figures, 11 tables

We measured the harmonic-space power spectrum of galaxy clustering auto-correlation from the Evolutionary Map of the Universe Pilot Survey 1 data (EMU PS1) and its cross-correlation with the lensing convergence map of cosmic microwave background (CMB) from Planck Public Release 4 at the linear scale range from $\ell=2$ to 500. We applied two flux density cuts at $0.18$ and $0.4$mJy on the radio galaxies observed at 944MHz and considered two source detection algorithms. We found the auto-correlation measurements from the two algorithms at the 0.18mJy cut to deviate for $\ell\gtrsim250$ due to the different criteria assumed on the source detection and decided to ignore data above this scale. We report a cross-correlation detection of EMU PS1 with CMB lensing at $\sim$5.5$\sigma$, irrespective of flux density cut. In our theoretical modelling we considered two redshift distribution simulation models that yield consistent results, a linear and a non-linear matter power spectrum, and two linear galaxy bias models. That is a constant redshift-independent galaxy bias $b(z)=b_g$ and a constant amplitude galaxy bias $b(z)=b_g/D(z)$. By fixing a cosmology model and considering a non-linear matter power spectrum, we measured a constant galaxy bias at $0.18$mJy ($0.4$mJy) with $b_g=2.32^{+0.41}_{-0.33}$ ($2.18^{+0.17}_{-0.25}$) and a constant amplitude bias with $b_g=1.72^{+0.31}_{-0.21}$ ($1.78^{+0.22}_{-0.15}$). When $\sigma_8$ is a free parameter for the same models at $0.18$mJy ($0.4$mJy) with the constant model we found $\sigma_8=0.68^{+0.16}_{-0.14}$ ($0.82\pm0.10$), while with the constant amplitude model we measured $\sigma_8=0.61^{+0.18}_{-0.20}$ ($0.78^{+0.11}_{-0.09}$), respectively. Our results agree at $1\sigma$ with the measurements from Planck CMB and the weak lensing surveys and also show the potential of cosmology studies with future radio continuum survey data., Comment: To be submitted to PASA. 22 pages, 9 figures, 4 tables

On-chip coherent laser sources are crucial for the future of photonic integrated circuits, yet progress has been hindered by the complex interplay between material quality, device geometry, and performance metrics. We combine high-throughput characterization, statistical analysis, experimental design, and multi-objective Bayesian optimization to accelerate the design process for low-threshold, high-yield III-V microring lasers with room-temperature operation at communication wavelengths. We demonstrate a 1.6$\times$ reduction in threshold over expert-designed configurations, achieving a 100% lasing yield that emits within the O-band with a median threshold as low as 33$\mu$J cm$^{-2}$ pulse$^{-1}$.

Neutrino-nucleus cross section measurements are needed to improve interaction modeling to meet the precision needs of neutrino experiments in efforts to measure oscillation parameters and search for physics beyond the Standard Model. We review the difficulties associated with modeling neutrino-nucleus interactions that lead to a dependence on event generators in oscillation analyses and cross section measurements alike. We then describe data-driven model validation techniques intended to address this model dependence. The method relies on utilizing various goodness-of-fit tests and the correlations between different observables and channels to probe the model for defects in the phase space relevant for the desired analysis. These techniques shed light on relevant mis-modeling, allowing it to be detected before it begins to bias the cross section results. We compare more commonly used model validation methods which directly validate the model against alternative ones to these data-driven techniques and show their efficacy with fake data studies. These studies demonstrate that employing data-driven model validation in cross section measurements represents a reliable strategy to produce robust results that will stimulate the desired improvements to interaction modeling.

Outflows are critical components of many astrophysical systems, including accreting compact binaries and active galactic nuclei (AGN). These outflows can significantly affect a system's evolution and alter its observational appearance by reprocessing the radiation produced by the central engine. Sirocco (Simulating Ionization and Radiation in Outflows Created by Compact Objects - or "the code formerly known as Python") is a Sobolev-based Monte Carlo ionization and radiative transfer code. It is designed to simulate the spectra produced by any system with an azimuthally-symmetric outflow, from spherical stellar winds to rotating, biconical accretion disc winds. Wind models can either be parametrized or imported, e.g. from hydrodynamical simulations. The radiation sources include an optically thick accretion disc and various central sources with flexible spectra and geometries. The code tracks the "photon packets" produced by the sources in any given simulation as they traverse and interact with the wind. The code assumes radiative near-equilibrium, so the thermal and ionization state can be determined iteratively from these interactions. Once the physical properties in the wind have converged, Sirocco can be used to generate synthetic spectra at a series of observer sightlines. Here, we describe the physical assumptions, operation, performance and limitations of the code. We validate it against tardis, cmfgen and cloudy, finding good agreement, and present illustrative synthetic spectra from disc winds in cataclysmic variables, tidal disruption events, AGN and X-ray binaries. Sirocco is publicly available on GitHub, alongside its associated data, documentation and sample input files covering a wide range of astrophysical applications., Comment: 26 pages, 16 figures. Submitted to MNRAS. This is the release paper for the SIROCCO code, which can be found at https://github.com/sirocco-rt/sirocco with links to documentation. Underlying data and figure scripts available at https://github.com/sirocco-rt/release-models -- comments on the code, paper or documentation are welcomed

Large neutrino liquid argon time projection chamber (LArTPC) experiments can broaden their physics reach by reconstructing and interpreting MeV-scale energy depositions, or blips, present in their data. We demonstrate new calorimetric and particle discrimination capabilities at the MeV energy scale using reconstructed blips in data from the MicroBooNE LArTPC at Fermilab. We observe a concentration of low energy ($<$3 MeV) blips around fiberglass mechanical support struts along the TPC edges with energy spectrum features consistent with the Compton edge of 2.614 MeV $^{208}$Tl decay $\gamma$ rays. These features are used to verify proper calibration of electron energy scales in MicroBooNE's data to few percent precision and to measure the specific activity of $^{208}$Tl in the fiberglass composing these struts, $(11.7 \pm 0.2 ~\text{(stat)} \pm 2.8~\text{(syst)})~\text{Bq/kg}$. Cosmogenically-produced blips above 3 MeV in reconstructed energy are used to showcase the ability of large LArTPCs to distinguish between low-energy proton and electron energy depositions. An enriched sample of low-energy protons selected using this new particle discrimination technique is found to be smaller in data than in dedicated CORSIKA cosmic ray simulations, suggesting either incorrect CORSIKA modeling of incident cosmic fluxes or particle transport modeling issues in Geant4., Comment: 19 pages, 15 figures total including the supplementary material section, 1 table. CC BY license

Magnetite, a naturally abundant mineral, frequently interacts with water in both natural settings and various technical applications, making the study of its surface chemistry highly relevant. In this work, we investigate the hydrogen bonding dynamics and the presence of hydroxyl species at the magnetite-water interface using a combination of neural network potential-based molecular dynamics simulations and sum frequency generation vibrational spectroscopy. Our simulations, which involved large water systems, allowed us to identify distinct interfacial species, such as dissociated hydrogen and hydroxide ions formed by water dissociation. Notably, water molecules near the interface exhibited a preference for dipole orientation towards the surface, with bulk-like water behavior only re-emerging beyond 60 {\AA} from the surface. The vibrational spectroscopy results aligned well with the simulations, confirming the presence of a hydrogen bond network in the surface ad-layers. The analysis revealed that surface-adsorbed hydroxyl groups orient their hydrogen atoms towards the water bulk. In contrast, hydrogen-bonded water molecules align with their hydrogen atoms pointing towards the magnetite surface.

We present a complete analysis of Fermi Large Area Telescope (LAT) data of GRB 221009A, the brightest Gamma-Ray Burst (GRB) ever detected. The burst emission above 30 MeV detected by the LAT preceded by 1 s the low-energy (< 10 MeV) pulse that triggered the Fermi Gamma-Ray Burst Monitor (GBM), as has been observed in other GRBs. The prompt phase of GRB 221009A lasted a few hundred seconds. It was so bright that we identify a Bad Time Interval (BTI) of 64 seconds caused by the extremely high flux of hard X-rays and soft gamma rays, during which the event reconstruction efficiency was poor and the dead time fraction quite high. The late-time emission decayed as a power law, but the extrapolation of the late-time emission during the first 450 seconds suggests that the afterglow started during the prompt emission. We also found that high-energy events observed by the LAT are incompatible with synchrotron origin, and, during the prompt emission, are more likely related to an extra component identified as synchrotron self-Compton (SSC). A remarkable 400 GeV photon, detected by the LAT 33 ks after the GBM trigger and directionally consistent with the location of GRB 221009A, is hard to explain as a product of SSC or TeV electromagnetic cascades, and the process responsible for its origin is uncertain. Because of its proximity and energetic nature, GRB 221009A is an extremely rare event., Comment: 60 pages, 38 figures, 9 tables

Tidal disruption events (TDEs) can generate non-spherical, relativistic and optically thick outflows. Simulations show that the radiation we observe is reprocessed by these outflows. According to a unified model suggested by these simulations, the spectral energy distributions (SEDs) of TDEs depend strongly on viewing angle: low [high] optical-to-X-ray ratios (OXRs) correspond to face-on [edge-on] orientations. Post-processing with radiative transfer codes have simulated the emergent spectra, but have so far been carried out only in a quasi-1D framework, with three atomic species (H, He and O). Here, we present 2.5D Monte Carlo radiative transfer simulations which model the emission from a non-spherical outflow, including a more comprehensive set of cosmically abundant species. While the basic trend of OXR increasing with inclination is preserved, the inherently multi-dimensional nature of photon transport through the non-spherical outflow significantly affects the emergent SEDs. Relaxing the quasi-1D approximation allows photons to preferentially escape in (polar) directions of lower optical depth, resulting in a greater variation of bolometric luminosity as a function of inclination. According to our simulations, inclination alone may not fully explain the large dynamic range of observed TDE OXRs. We also find that including metals, other than Oxygen, changes the emergent spectra significantly, resulting in stronger absorption and emission lines in the extreme ultraviolet, as well a greater variation in the OXR as a function of inclination. Whilst our results support previously proposed unified models for TDEs, they also highlight the critical importance of multi-dimensional ionization and radiative transfer., Comment: 17 pages, 15 figures. Submitted to MNRAS

In this paper, we consider an optimal distributed control problem for a reaction-diffusion-based SIR epidemic model with human behavioral effects. We develop a model wherein non-pharmaceutical intervention methods are implemented, but a portion of the population does not comply with them, and this noncompliance affects the spread of the disease. Drawing from social contagion theory, our model allows for the spread of noncompliance parallel to the spread of the disease. The quantities of interest for control are the reduction in infection rate among the compliant population, the rate of spread of noncompliance, and the rate at which non-compliant individuals become compliant after, e.g., receiving more or better information about the underlying disease. We prove the existence of global-in-time solutions for fixed controls and study the regularity properties of the resulting control-to-state map. The existence of optimal control is then established in an abstract framework for a fairly general class of objective functions. Necessary first--order optimality conditions are obtained via a Lagrangian based stationarity system. We conclude with a discussion regarding minimization of the size of infected and non-compliant populations and present simulations with various parameters values to demonstrate the behavior of the model.

The angular correlation is a method for measuring the distribution of structure in the Universe, through the statistical properties of the angular distribution of galaxies on the sky. We measure the angular correlation of galaxies from the second data release of the GaLactic and Extragalactic All-sky Murchison Widefield Array eXtended survey (GLEAM-X) survey, a low-frequency radio survey covering declinations below +30 degrees. We find an angular distribution consistent with the LambdaCDM cosmological model assuming the best fitting cosmological parameters from Planck Collaboration et al. (2020). We fit a bias function to the discrete tracers of the underlying matter distribution, finding a bias that evolves with redshift in either a linear or exponential fashion to be a better fit to the data than a constant bias. We perform a covariance analysis to obtain an estimation of the properties of the errors, by analytic, jackknife and sample variance means. Our results are consistent with previous studies on the topic, and also the predictions of the LambdaCDM cosmological model.

Determining the local coordination of the active site is a pre-requisite for the reliable modeling of single-atom catalysts (SACs). Obtaining such information is difficult on powder-based systems, so much emphasis is placed on density functional theory-based computations based on idealized low-index surfaces of the support. In this work, we investigate how Pt atoms bind to the (1-102) facet of Fe2O3, a common support material in SAC. Using a combination of scanning tunneling microscopy (STM), x-ray photoelectron spectroscopy (XPS), and an extensive computational evolutionary search, we find that Pt atoms significantly reconfigure the support lattice to facilitate a pseudo-linear coordination to surface oxygen atoms. Despite breaking three surface Fe-O bonds, this geometry is favored by 0.84 eV over the best configuration involving an unperturbed support. We suggest that the linear O-Pt-O configuration is common in reactive Pt-based SAC systems because it balances thermal stability with the ability to adsorb reactants from the gas phase, and that extensive structural searches are likely necessary to determine realistic active site geometry in single-atom catalysis.

Water-solid interfaces pervade the natural environment and modern technology. On some surfaces, water-water interactions induce the formation of partially dissociated interfacial layers; understanding why is important to model processes in catalysis or mineralogy. The complexity of the partially dissociated structures often make it difficult to probe them in a quantitative manner. Here, we utilize normal incidence x-ray standing waves (NIXSW) to study the structure of partially dissociated water dimers (H2O-OH) at the Fe2O3(012) surface (also called (1-102) or R-cut surface); a system simple enough to be tractable, yet complex enough to capture the essential physics. We find the H2O and terminal OH groups to be the same height above the surface within experimental error (1.45 +/- 0.04 Angstrom and 1.47 +/- 0.02 Angstrom, respectively), in line with DFT-based calculations that predict comparable Fe-O bond lengths for both water and OH species. This result is understood in the context of cooperative binding, where the formation of the H-bond between adsorbed H2O and OH induces the H2O to bind more strongly, and OH to bind more weakly compared to when these species are isolated on the surface. The surface OH formed by the liberated proton is found to be in plane with a bulk truncated (012) surface (-0.01 +/- 0.02 Angstrom). DFT calculations based on various functionals correctly model the cooperative effect, but overestimate the water-surface interaction.

With the number of supernovae observed expected to drastically increase thanks to large-scale surveys like the Dark Energy Spectroscopic Instrument (DESI), it is necessary that the tools we use to classify these objects keep up with this increase. We previously created Supernova Tagging and Classification (STag) to address this problem by employing machine learning techniques alongside logistic regression in order to assign 'tags' to spectra based on spectral features. STag II is a continuation of this work, which now makes use of model supernova spectra combined with real DESI spectra in order to train STag to better deal with realistic data. We also make use of the rlap score as a trustworthiness cut, making for a more robust and accurate supernova classifier than before., Comment: 27 pages, 7 figures. The STag code is available at https://github.com/wdavison909/STag

Knowledge management (KM) involves collecting, organizing, storing, and disseminating information to improve decision-making, innovation, and performance. Implementing KM at scale has become essential for organizations to effectively leverage vast accessible data. This paper is a compilation of concepts that emerged from KM workshops hosted by EMBL-EBI, attended by SMEs and industry. We provide guidance on envisioning, executing, evaluating, and evolving knowledge management platforms. We emphasize essential considerations such as setting knowledge domain boundaries and measuring success, as well as the importance of making knowledge accessible for downstream applications and non-computational users and highlights necessary personal and organizational skills for success. We stress the importance of collaboration and the need for convergence on shared principles and commitment to provide or seek resources to advance KM. The community is invited to join the journey of KM and contribute to the advancement of the field by applying and improving on the guidelines described., Comment: 18 pages, 1 figure

A significant challenge in measurements of neutrino oscillations is reconstructing the incoming neutrino energies. While modern fully-active tracking calorimeters such as liquid argon time projection chambers in principle allow the measurement of all final state particles above some detection threshold, undetected neutrons remain a considerable source of missing energy with little to no data constraining their production rates and kinematics. We present the first demonstration of tagging neutrino-induced neutrons in liquid argon time projection chambers using secondary protons emitted from neutron-argon interactions in the MicroBooNE detector. We describe the method developed to identify neutrino-induced neutrons and demonstrate its performance using neutrons produced in muon-neutrino charged current interactions. The method is validated using a small subset of MicroBooNE's total dataset. The selection yields a sample with $60\%$ of selected tracks corresponding to neutron-induced secondary protons.

We present a deep learning-based method for estimating the neutrino energy of charged-current neutrino-argon interactions. We employ a recurrent neural network (RNN) architecture for neutrino energy estimation in the MicroBooNE experiment, utilizing liquid argon time projection chamber (LArTPC) detector technology. Traditional energy estimation approaches in LArTPCs, which largely rely on reconstructing and summing visible energies, often experience sizable biases and resolution smearing because of the complex nature of neutrino interactions and the detector response. The estimation of neutrino energy can be improved after considering the kinematics information of reconstructed final-state particles. Utilizing kinematic information of reconstructed particles, the deep learning-based approach shows improved resolution and reduced bias for the muon neutrino Monte Carlo simulation sample compared to the traditional approach. In order to address the common concern about the effectiveness of this method on experimental data, the RNN-based energy estimator is further examined and validated with dedicated data-simulation consistency tests using MicroBooNE data. We also assess its potential impact on a neutrino oscillation study after accounting for all statistical and systematic uncertainties and show that it enhances physics sensitivity. This method has good potential to improve the performance of other physics analyses.

SBND is the near detector of the Short-Baseline Neutrino program at Fermilab. Its location near to the Booster Neutrino Beam source and relatively large mass will allow the study of neutrino interactions on argon with unprecedented statistics. This paper describes the expected performance of the SBND photon detection system, using a simulated sample of beam neutrinos and cosmogenic particles. Its design is a dual readout concept combining a system of 120 photomultiplier tubes, used for triggering, with a system of 192 X-ARAPUCA devices, located behind the anode wire planes. Furthermore, covering the cathode plane with highly-reflective panels coated with a wavelength-shifting compound recovers part of the light emitted towards the cathode, where no optical detectors exist. We show how this new design provides a high light yield and a more uniform detection efficiency, an excellent timing resolution and an independent 3D-position reconstruction using only the scintillation light. Finally, the whole reconstruction chain is applied to recover the temporal structure of the beam spill, which is resolved with a resolution on the order of nanoseconds., Comment: 21 pages, 17 figures

The aim of this paper is to give a new explicit construction of Lusztig's asymptotic algebra in affine type $\mathsf{A}$. To do so, we construct a balanced system of cell modules, prove an asymptotic version of the Plancherel Theorem and develop a relative version of the Satake Isomorphism for each two-sided Kazhdan-Lusztig cell.

We seek to identify genes involved in Parkinson's Disease (PD) by combining information across different experiment types. Each experiment, taken individually, may contain too little information to distinguish some important genes from incidental ones. However, when experiments are combined using the proposed statistical framework, additional power emerges. The fundamental building block of the family of statistical models that we propose is a hierarchical three-group mixture of distributions. Each gene is modeled probabilistically as belonging to either a null group that is unassociated with PD, a deleterious group, or a beneficial group. This three-group formalism has two key features. By apportioning prior probability of group assignments with a Dirichlet distribution, the resultant posterior group probabilities automatically account for the multiplicity inherent in analyzing many genes simultaneously. By building models for experimental outcomes conditionally on the group labels, any number of data modalities may be combined in a single coherent probability model, allowing information sharing across experiment types. These two features result in parsimonious inference with few false positives, while simultaneously enhancing power to detect signals. Simulations show that our three-groups approach performs at least as well as commonly-used tools for GWAS and RNA-seq, and in some cases it performs better. We apply our proposed approach to publicly-available GWAS and RNA-seq datasets, discovering novel genes that are potential therapeutic targets., Comment: 26 pages, 6 figures, 4 tables

Single-atom catalysts are potentially ideal model systems to investigate structure-function relationships in catalysis, if the active sites can be uniquely determined. In this work, we study the interaction of C2H4 with a model Rh/Fe3O4(001) catalyst that features 2-, 5-, and 6-fold coordinated Rh adatoms, as well as Rh clusters. Using multiple surface-sensitive techniques in combination with calculations of density functional theory (DFT), we follow the thermal evolution of the system and disentangle the behavior of the different species. C2H4 adsorption is strongest at the 2-fold coordinated Rh1 with a DFT-determined adsorption energy of -2.26 eV. However, desorption occurs at lower temperatures than expected because the Rh migrates into substitutional sites within the support, where the molecule is more weakly bound. Adsorption at the 5-fold coordinated Rh sites is predicated to -1.49 eV, but the superposition of this signal with that from small Rh clusters and additional heterogeneity leads to a broad C2H4 desorption shoulder in TPD above room temperature.

Active wavelength-scale optoelectronic components are widely used in photonic integrated circuitry, however coherent sources of light -- namely optical lasers -- remain the most challenging component to integrate. Semiconductor nanowire lasers represent a flexible class of light source where each nanowire is both gain material and cavity; however, strong coupling between these properties and the performance leads to inhomogeneity across the population. While this has been studied and optimized for individual material systems, no architecture-wide insight is available. Here, nine nanowire laser material systems are studied and compared using 55,516 nanowire lasers to provide statistically robust insight into performance. These results demonstrate that, while it may be important to optimise internal quantum efficiency for certain materials, cavity effects are always critical. Our study provides a roadmap to optimize the performance of nanowire lasers made from any material: this can be achieved by ensuring a narrow spread of lengths and end-facet reflectivities.

In this paper, we consider the problem of visual scanning mechanism underpinning sensorimotor tasks, such as walking and driving, in dynamic environments. We exploit eye tracking data for offering two new cognitive effort measures in visual scanning behavior of virtual driving. By utilizing the retinal flow induced by fixation, two novel measures of cognitive effort are proposed through the importance of grids in the viewing plane and the concept of information quantity, respectively. Psychophysical studies are conducted to reveal the effectiveness of the two proposed measures. Both these two cognitive effort measures have shown their significant correlation with pupil size change. Our results suggest that the quantitative exploitation of eye tracking data provides an effective approach for the evaluation of sensorimotor activities.

Nanowire-based plasmonic lasers are now established as nano-sources of coherent radiation, appearing as suitable candidates for integration into next-generation nanophotonic circuitry. However, compared to their photonic counterparts, their relatively high losses and large lasing thresholds still pose a burdening constraint on their scalability. In this study, the lasing characteristics of ZnO nanowires on Ag and Al substrates, operating as optically-pumped short-wavelength plasmonic nanolasers, are systematically investigated in combination with the size-dependent performance of the hybrid cavity. A hybrid nanomanipulation-assisted single nanowire optical characterization combined with high-throughput PL spectroscopy enables the correlation of the lasing characteristics to the metal substrate and the nanowire diameter. The results evidence that the coupling between excitons and surface plasmons is closely tied to the relationship between substrate dispersive behavior and nanowire diameter. Such coupling dictates the degree to which the lasing character, be it more plasmonic- or photonic-like, can define the stimulated emission features and, as a result, the device performance., Comment: 21 pages, 12 figures, journal paper draft

We present the MOST Hosts survey (Multi-Object Spectroscopy of Transient Hosts). The survey is planned to run throughout the five years of operation of the Dark Energy Spectroscopic Instrument (DESI) and will generate a spectroscopic catalog of the hosts of most transients observed to date, in particular all the supernovae observed by most public, untargeted, wide-field, optical surveys (PTF/iPTF, SDSS II, ZTF, DECAT, DESIRT). Scientific questions for which the MOST Hosts survey will be useful include Type Ia supernova cosmology, fundamental plane and peculiar velocity measurements, and the understanding of the correlations between transients and their host galaxy properties. Here, we present the first release of the MOST Hosts survey: 21,931 hosts of 20,235 transients. These numbers represent 36% of the final MOST Hosts sample, consisting of 60,212 potential host galaxies of 38,603 transients (a transient can be assigned multiple potential hosts). Of these galaxies, 40% do not appear in the DESI primary target list and therefore require a specific program like MOST Hosts. Of all the transients in the MOST Hosts list, only 26.7% have existing classifications, and so the survey will provide redshifts (and luminosities) for nearly 30,000 transients. A preliminary Hubble diagram and a transient luminosity-duration diagram are shown as examples of future potential uses of the MOST Hosts survey. The survey will also provide a training sample of spectroscopically observed transients for photometry-only classifiers, as we enter an era when most newly observed transients will lack spectroscopic classification. The MOST Hosts DESI survey data will be released through the Wiserep platform on a rolling cadence and updated to match the DESI releases. Dates of future releases and updates are available through the https://mosthosts.desi.lbl.gov website., Comment: Submitted to ApJS

Identifying terrain within satellite image data is a key issue in geographical information sciences, with numerous environmental and safety implications. Many techniques exist to derive classifications from spectral data captured by satellites. However, the ability to reliably classify vegetation remains a challenge. In particular, no precise methods exist for classifying forest vs. non-forest vegetation in high-level satellite images. This paper provides an initial proposal for a static, algorithmic process to identify forest regions in satellite image data through texture features created from detected edges and the NDVI ratio captured by Sentinel-2 satellite images. With strong initial results, this paper also identifies the next steps to improve the accuracy of the classification and verification processes.

We report the first double-differential cross section measurement of neutral-current neutral pion (NC$\pi^0$) production in neutrino-argon scattering, as well as single-differential measurements of the same channel in terms of final states with and without protons. The kinematic variables of interest for these measurements are the $\pi^0$ momentum and the $\pi^0$ scattering angle with respect to the neutrino beam. A total of 4971 candidate NC$\pi^0$ events fully-contained within the MicroBooNE detector are selected using data collected at a mean neutrino energy of $\sim 0.8$~GeV from $6.4\times10^{20}$ protons on target from the Booster Neutrino Beam at the Fermi National Accelerator Laboratory. After extensive data-driven model validation to ensure unbiased unfolding, the Wiener-SVD method is used to extract nominal flux-averaged cross sections. The results are compared to predictions from commonly used neutrino event generators, which tend to overpredict the measured NC$\pi^0$ cross section, especially in the 0.2-0.5~GeV/c $\pi^0$ momentum range and at forward scattering angles. Events with at least one proton present in the final state are also underestimated. This data will help improve the modeling of NC$\pi^0$ production, which represents a major background in measurements of charge-parity violation in the neutrino sector and in searches for new physics beyond the Standard Model.

We present a measurement of neutral pion production in charged-current interactions using data recorded with the MicroBooNE detector exposed to Fermilab's booster neutrino beam. The signal comprises one muon, one neutral pion, any number of nucleons, and no charged pions. Studying neutral pion production in the MicroBooNE detector provides an opportunity to better understand neutrino-argon interactions, and is crucial for future accelerator-based neutrino oscillation experiments. Using a dataset corresponding to $6.86 \times 10^{20}$ protons on target, we present single-differential cross sections in muon and neutral pion momenta, scattering angles with respect to the beam for the outgoing muon and neutral pion, as well as the opening angle between the muon and neutral pion. Data extracted cross sections are compared to generator predictions. We report good agreement between the data and the models for scattering angles, except for an over-prediction by generators at muon forward angles. Similarly, the agreement between data and the models as a function of momentum is good, except for an underprediction by generators in the medium momentum ranges, $200-400$ MeV for muons and $100-200$ MeV for pions.

Infrared Reflection Absorption Spectroscopy (IRAS) on dielectric single crystals is challenging because the optimal incidence angles for light-adsorbate interaction coincide with regions of low IR reflectivity. Here, we introduce an optimized IRAS setup that maximizes the signal-to-noise ratio for non-metals. This is achieved by maximizing light throughput, and by selecting optimal incidence angles that directly impact the peak heights in the spectra. The setup uses a commercial FTIR spectrometer and is usable in ultra-high vacuum (UHV). Specifically, the design features sample illumination and collection mirrors with a high numerical aperture inside the UHV system, and an adjustable aperture to select the incidence angle range on the sample. This is important for p-polarized measurements on dielectrics, because the peaks in the spectra reverse direction at the Brewster angle (band inversion). The system components are connected precisely via a single flange, ensuring long-term stability. We studied the signal-to-noise (SNR) variation in p-polarized IRAS spectra for one monolayer of CO on TiO2(110) as a function of incidence angle range, where a maximum signal-to-noise ratio of 70 was achieved at 4 cm-1 resolution in five minutes measurement time. The capabilities for s-polarization are demonstrated by measuring one monolayer D2O adsorbed on a TiO2(110) surface, where a SNR of 65 was achieved at a delta_R/R0 peak height of 1.4x10-4 in twenty minutes., Comment: supplementary information included