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1,239 results on '"Pötter R"'

2. Clinical and imaging findings in cervical cancer and their impact on FIGO and TNM staging – An analysis from the EMBRACE study

Author

Knoth, J., Pötter, R., Jürgenliemk-Schulz, I.M., Haie-Meder, C., Fokdal, L., Sturdza, A., Hoskin, P., Mahantshetty, U., Segedin, B., Bruheim, K., Wiebe, E., Rai, B., Cooper, R., van der Steen-Banasik, E., van Limbergen, E., Pieters, B.R., Sundset, M., Tan, L.T., Nout, R.A., Tanderup, K., Kirisits, C., Nesvacil, N., Lindegaard, J.C., and Schmid, M.P.

Published
2020
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3. Imaging-based target volume reduction in chemoradiotherapy for locally advanced non-small-cell lung cancer (PET-Plan): a multicentre, open-label, randomised, controlled trial

Author

Grosu, A L, Weber, W, Meyer, P, Hoffmanns, H, Nestle, U, Aurisch, R, Schäfer, W, Hehr, T, Eschmann, S M, Dornoff, W, Siekmeyer, B, Trampert, L, Gademann, G, Brunner, T, Amthauer, A, Ricke, J, Pech, M, Rübe, C, Kirsch, C M, Ezzidin, S, Schmidberger, H, Schreckenberger, M, Bamberg, M, Zips, D, Bares, R, La Fougere, C, Budach, V, Brenner, W, Beck, M, Freiherr von Gumppenberg, R, Aebersold, D, Krause, T, Feldmann, H J, Hertel, A, Stüben, G, Sciuk, J, Annweiler, H, Holl, G, Oehler, W, Schlöcker, I, Baum, R, Kimmig, B, Dunst, J, Henze, E, Lützen, U, Schwaiger, M, Strehle, K, Alberti, W, Piroth, M, Tosch, M, Pötter, R, Widder, J, Herold, C, Freund, U, Momm, F, Sautter-Bihl, M L, Tatsch, K, Hildebrandt, G, Krause, B, Nestle, Ursula, Schimek-Jasch, Tanja, Kremp, Stephanie, Schaefer-Schuler, Andrea, Mix, Michael, Küsters, Andreas, Tosch, Marco, Hehr, Thomas, Eschmann, Susanne Martina, Bultel, Yves-Pierre, Hass, Peter, Fleckenstein, Jochen, Thieme, Alexander, Stockinger, Marcus, Dieckmann, Karin, Miederer, Matthias, Holl, Gabriele, Rischke, H Christian, Gkika, Eleni, Adebahr, Sonja, König, Jochem, and Grosu, Anca-Ligia

Published
2020
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7. OC-0129 Impact of brachytherapy applicator on morbidity and local control in cervix cancer: EMBRACE study

Author

Serban, M., primary, Spampinato, S., additional, de Leeuw, A., additional, Fortin, I., additional, Nevascil, N., additional, Kirisits, C., additional, Schmid, M., additional, Mahantshetty, U., additional, Hoskin, P., additional, Segedin, B., additional, Bruheim, K., additional, Huang, F., additional, Pieters, B., additional, Nout, R., additional, Pötter, R., additional, Kirchheiner, K., additional, Jürgenliemk-Schulz, I., additional, and Tanderup, K., additional

Published
2023
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10. Vaginal changes, sexual functioning and distress of women with locally advanced cervical cancer treated in the EMBRACE vaginal morbidity substudy

Author

MS Radiotherapie, Cancer, Suvaal, I, Kirchheiner, K, Nout, R A, Sturdza, A E, Van Limbergen, E, Lindegaard, J C, Putter, H, Jürgenliemk-Schulz, I M, Chargari, C, Tanderup, K, Pötter, R, Creutzberg, C L, Ter Kuile, M M, MS Radiotherapie, Cancer, Suvaal, I, Kirchheiner, K, Nout, R A, Sturdza, A E, Van Limbergen, E, Lindegaard, J C, Putter, H, Jürgenliemk-Schulz, I M, Chargari, C, Tanderup, K, Pötter, R, Creutzberg, C L, and Ter Kuile, M M

Published
2023

11. Patient-reported sexual frequency and vaginal functioning in patients with locally advanced cervical cancer following definitive radiochemotherapy and image-guided adaptive brachytherapy (EMBRACE study)

Author

Kirchheiner, K, Jürgenliemk-Schulz, I M, Haie-Meder, C, Lindegaard, J C, Sturdza, A, Mahantshetty, U, Segedin, B, Bruheim, K, Rai, B, Cooper, R, van der Steen-Banasik, E, Wiebe, E, Sundset, M, van Limbergen, E, Villafranca, E, Westerveld, H, Tan, L T, Tanderup, K, Pötter, R, and Nout, R A

Published
2019
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14. Grundlagen und Technik der Brachytherapie

Author

Fritz, P., Roth, S.L., Pötter, R., Hensley, F.W., Muskalla, K., Weber, K.-J., Wannenmacher, M., Macha, H.-N., Dimopoulos, J., Wannenmacher, Michael, editor, Wenz, Frederik, editor, and Debus, Jürgen, editor

Published
2013
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16. Grundlagen und Technik der Brachytherapie

Author

Fritz, P., Roth, S. L., Pötter, R., Hensley, F. W., Muskalla, K., Weber, K. -J., Wannenmacher, M., Macha, H. -N., Dimopoulos, J., Wannenmacher, M., editor, Debus, J., editor, and Wenz, F., editor

Published
2006
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17. Strahlentherapie

Author

Pötter, R., Georg, D., Handl-Zeller, L., Salamon, J., Selzer, E., Hiddemann, Wolfgang, Huber, Heinz, and Bartram, Claus R.

Published
2004
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18. Kutane Non-Hodgkin-Lymphome

Author

Burg, G., Schmid, M. Hess, Nestle, F. O., Pötter, R., Handl-Zeller, L., Dummer, R., Schmoll, Hans-Joachim, editor, Höffken, Klaus, editor, and Possinger, Kurt, editor

Published
1999
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19. Allgemeine Chirurgische Onkologie

Author

Steindorfer, P., Smola, M. G., Deutinger, M., Haid, A., Hausmaninger, H., Herbst, F., Hölbling, N., Horcher, E., Jakesz, R., Jatzko, G. R., Karner, J., Koller, R., Kostron, H., Manfreda, D., Marczell, A., Niederle, B., Pötter, R., Rabl, H., Reiner, G., Ritschl, P., Rosen, H., Schwarz, F. Ch., Smolle-Jüttner, F., Stierer, M., Waclawiczek, H. W., Würinger, E., Vinzenz, K., Zimmermann, G., and Smola, M. G., editor

Published
1999
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20. Weichteilsarkome der Erwachsenen

Author

Ritschl, P., Smola, M. G., Beham, A., Böheim, K., Depisch, D., Dinstl, K., Dobrowsky, W., Jakse, R., Kotz, R., Piza, H., Pötter, R., Salzer-Kuntschik, M., Vinzenz, K., Zielinski, Ch., and Smola, M. G., editor

Published
1999
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22. OC-0503 Effect of dose and fractionation de-escalation in low-risk cervix cancer treated with EBRT and BT

Author

Serban, M., primary, Gallois, M., additional, Urtubey, T., additional, Nout, R., additional, de Leeuw, A., additional, Fokdal, L., additional, Assenholt, M., additional, Spampinato, S., additional, Bruheim, K., additional, Segedin, B., additional, Chopra, S., additional, Schmid, M., additional, Nesvacil, N., additional, Ecker, S., additional, Kirchheiner, K., additional, Pötter, R., additional, Westerveld, H., additional, Huang, F., additional, Velema, L., additional, Tan, L.T., additional, Valgma, M., additional, Mathiesen, H., additional, Lindegaard, J., additional, Jürgenliemk-Schulz, I., additional, and Tanderup, K., additional

Published
2022
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23. OC-0830 Systemic recurrence after primary chemoradiation in cervical cancer patients – an EMBRACE analysis

Author

Knoth, J., primary, Nout, R., additional, Mahantshetty, U., additional, Jürgenliemk-Schulz, I., additional, Haie-Meder, C., additional, Fokdal, L.U., additional, Sturdza, A., additional, Hoskin, P., additional, Segedin, B., additional, Bruheim, K., additional, Huang, F., additional, Rai, B., additional, Cooper, R., additional, van der Steen-Banasik, E., additional, van Limbergen, E., additional, Pieters, B.R., additional, Tan, L.T., additional, Kannan, S., additional, de Leeuw, A.A., additional, Nesvacil, N., additional, Tanderup, K., additional, Kirisits, C., additional, Lindegaard, J.C., additional, Pötter, R., additional, and Schmid, M.P., additional

Published
2022
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24. OC-0588 Impact of persistent symptoms on long-term quality of life of cervical cancer survivors in EMBRACE I

Author

Spampinato, S., primary, Tanderup, K., additional, Nout, R., additional, Smet, S., additional, Lindegaard, J.C., additional, Fokdal, L.U., additional, Pötter, R., additional, Sturdza, A., additional, Segedin, B., additional, Jürgenliemk-Schulz, I., additional, Bruheim, K., additional, Mahantshetty, U., additional, Chargari, C., additional, Rai, B., additional, Cooper, R., additional, van der Steen-Banasik, E., additional, Sundset, M., additional, Wiebe, E., additional, Villafranca, E., additional, Van Limbergen, E., additional, Chopra, S., additional, and Kirchheiner, K., additional

Published
2022
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26. Kutane Non-Hodgkin-Lymphome

Author

Burg, G., Dommann, S., Pötter, R., Schlappack, O., Dummer, R., Schmoll, Hans-Joachim, editor, Höffken, Klaus, editor, and Possinger, Kurt, editor

Published
1997
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27. Late Side Effects of Pediatric Radiotherapy

Author

Pötter, R., Herfarth, Ch., editor, Senn, H.-J., editor, Baum, M., editor, Diehl, V., editor, Gutzwiller, F., editor, Rajewsky, M. F., editor, Wannenmacher, Michael, editor, Hinkelbein, Wolfgang, editor, Bruggmoser, Gregor, editor, and Frommhold, Hermann, editor

Published
1993
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28. Subclinical Impairment of Renal Function After Radiotherapy for Hodgkin’s Disease in Children

Author

Pötter, R., Roes, F., Schellong, G., Bartenstein, P., Brämswig, J. H., von Lengerke, H.-J., Rath, B., Mohring, R., Rossi, R., Herfarth, Ch., editor, Senn, H.-J., editor, Baum, M., editor, Diehl, V., editor, Gutzwiller, F., editor, Rajewsky, M. F., editor, Wannenmacher, Michael, editor, Hinkelbein, Wolfgang, editor, Bruggmoser, Gregor, editor, and Frommhold, Hermann, editor

Published
1993
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29. Side-Effects After Combination Therapy for Ewing’s Sarcoma

Author

Pötter, R., Kuhnen, C., Ritter, J., Rath, B., Wuismann, P., von Eiff, M., von Lengerke, H.-J., Brämswig, J. H., Paulus, S., Herfarth, Ch., editor, Senn, H.-J., editor, Baum, M., editor, Diehl, V., editor, Gutzwiller, F., editor, Rajewsky, M. F., editor, Wannenmacher, Michael, editor, Hinkelbein, Wolfgang, editor, Bruggmoser, Gregor, editor, and Frommhold, Hermann, editor

Published
1993
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46. OC-0296 Risk factors for severe gastrointestinal morbidity in locally advanced cervix cancer (EMBRACE study)

Author

Spampinato, S., primary, Jensen, N.B., additional, Fokdal, L.U., additional, Pötter, R., additional, Haie-Meder, C., additional, Lindegaard, J.C., additional, Schmid, M.P., additional, Sturdza, A., additional, Jürgenliemk-Schulz, I.M., additional, Mahantshetty, U., additional, Segedin, B., additional, Hoskin, P., additional, Bruheim, K., additional, Rai, B., additional, Wiebe, E., additional, Cooper, R., additional, van der Steen-Banasik, E., additional, Van Limbergen, E., additional, Kirisits, C., additional, Nout, R.A., additional, Chopra, S., additional, Kirchheiner, K., additional, and Tanderup, K., additional

Published
2021
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47. OC-0295 New Prognostic factors in locally advanced cervical cancer treated with MR-IGABT in EMBRACE Study.

Author

Mahantshetty, U., primary, Schmid, M., additional, Kirisits, C., additional, Tanderup, K., additional, Haie-Meder, C., additional, Fokdal, L., additional, Sturdza, A., additional, Hoskin, P., additional, Segredin, B., additional, Bruheim, K., additional, Huang, F., additional, Rai, B., additional, Cooper, R., additional, van der Steen-Banasik, E., additional, van Limbergen, E., additional, Pieters, B., additional, Tan, L.T., additional, Hawaldar, R., additional, Kannan, S., additional, Nout, R., additional, de Leeuw, A.A.C., additional, Nesvacil, N., additional, Jürgenliemk-Schulz, I., additional, Lindegaard, J., additional, and Pötter, R., additional

Published
2021
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48. MRI-guided adaptive brachytherapy in locally advanced cervical cancer (EMBRACE-I): a multicentre prospective cohort study

Author

Pötter R., Tanderup K., Schmid M.P., Jürgenliemk-Schulz I., Haie-Meder C., Fokdal L.U., Sturdza A.E., Hoskin P., Mahantshetty U., Segedin B., Bruheim K., Huang F., Rai B., Cooper R., van der Steen-Banasik E., Van Limbergen E., Pieters B.R., Tan L.-T., Nout R.A., De Leeuw A.A.C., Ristl R., Petric P., Nesvacil N., Kirchheiner K., Kirisits C., Lindegaard J.C., Chargari C., Dumas I., Lowe G., Swamidas J., Hudej R., Paulsen Hellebust T., Menon G., Oinam A.S., Bownes P., Christiaens M., De Brabandere M., Janssen H., Oosterveld B., Koedooder K., Langeland Marthinsen A.B., Sundset M., Whitney D., Ketelaars M., Lutgens L.C.H.W., Reinniers B., Mora I., Villafranca E., Antal G., Hadjiev J., Bachand F., Batchelar D., Erickson B., Rownd J., Jacobson G., Kim Y., Anttila M., Palmgren J.-E., An J., Assenholt M.S., Banerjee S., Bentzen S., Berger T., Dankulchai P., Diendorfer T., Dilworth I., Dimopoulos J., Dörr E., Ecker S., Federico M., Fidarova E., Fortin I., Georg P., Gora J., Hegazy N., Jastaniyah N., Jensen N.B.K., Liederer T., Majercakova K., Misimovic D., Motisi L., Najjari Jamal D., Nkiwane K., Schwartz-Vittrup A., Serban M., Smet S., Spampinato S., Trnkova P., Valgma M., Westerveld H., Wong J.S.Y., Yoshida K., and EMBRACE Collaborative Group

Subjects
Asia, diagnostic imaging, Brachytherapy, cisplatin, uterine cervix carcinoma, morbidity, image guided radiotherapy, external beam radiotherapy, Article, Disease-Free Survival, multiple cycle treatment, chemoradiotherapy, volumetric modulated arc therapy, cancer control, fistula, follow up, urogenital tract disease, International Federation of Gynecology and Obstetrics, uterine cervix tumor, human, procedures, nuclear magnetic resonance imaging, outcome assessment, disease free survival, lymph node metastasis, cancer staging, adult, clinical trial, cohort analysis, major clinical study, intensity modulated radiation therapy, Europe, aged, multicenter study, female, quality of life, priority journal, North America, observational study, pathology, conformal radiotherapy, radiation dose, image guided adaptive brachytherapy, uterine cervix cancer, prospective study
Abstract

Background: The concept of the use of MRI for image-guided adaptive brachytherapy (IGABT) in locally advanced cervical cancer was introduced 20 years ago. Here, we report on EMBRACE-I, which aimed to evaluate local tumour control and morbidity after chemoradiotherapy and MRI-based IGABT. Methods: EMBRACE-I was a prospective, observational, multicentre cohort study. Data from patients from 24 centres in Europe, Asia, and North America were prospectively collected. The inclusion criteria were patients older than 18 years, with biopsy-proven squamous cell carcinoma, adenocarcinoma, or adenosquamous carcinoma of the uterine cervix, The International Federation of Gynecology and Obstetrics (FIGO) stage IB–IVA disease or FIGO stage IVB disease restricted to paraaortic lymph metastasis below the L1–L2 interspace, suitable for curative treatment. Treatment consisted of chemoradiotherapy (weekly intravenous cisplatin 40 mg/m2, 5–6 cycles, 1 day per cycle, plus 45–50 Gy external-beam radiotherapy delivered in 1·8–2 Gy fractions) followed by MRI-based IGABT. The MRI-based IGABT target volume definition and dose reporting was according to Groupe Européen de Curiethérapie European Society for Radiation Oncology recommendations. IGABT dose prescription was open according to institutional practice. Local control and late morbidity were selected as primary endpoints in all patients available for analysis. The study was registered with ClinicalTrials.gov, NCT00920920. Findings: Patient accrual began on July 30, 2008, and closed on Dec 29, 2015. A total of 1416 patients were registered in the database. After exclusion for not meeting patient selection criteria before treatment, being registered but not entered in the database, meeting the exclusion criteria, and being falsely excluded, data from 1341 patients were available for analysis of disease and data from 1251 patients were available for assessment of morbidity outcome. MRI-based IGABT including dose optimisation was done in 1317 (98·2%) of 1341 patients. Median high-risk clinical target volume was 28 cm3 (IQR 20–40) and median minimal dose to 90% of the clinical target volume (D90%) was 90 Gy (IQR 85–94) equi-effective dose in 2 Gy per fraction. At a median follow-up of 51 months (IQR 20–64), actuarial overall 5-year local control was 92% (95% CI 90–93). Actuarial cumulative 5-year incidence of grade 3–5 morbidity was 6·8% (95% CI 5·4–8·6) for genitourinary events, 8·5% (6·9–10·6) for gastrointestinal events, 5·7% (4·3–7·6) for vaginal events, and 3·2% (2·2–4·5) for fistulae. Interpretation: Chemoradiotherapy and MRI-based IGABT result in effective and stable long-term local control across all stages of locally advanced cervical cancer, with a limited severe morbidity per organ. These results represent a positive breakthrough in the treatment of locally advanced cervical cancer, which might be used as a benchmark for clinical practice and all future studies. Funding: Medical University of Vienna, Aarhus University Hospital, Elekta AB, and Varian Medical Systems. © 2021 Elsevier Ltd

Published
2021
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49. Impact of transitioning to an online course – A report from the ESTRO gyn teaching course

Author

MS Radiotherapie, Cancer, Tan, L. T., Tanderup, K., Nappa, A., Petric, P., Jürgenliemk-Schulz, I. M., Serban, M., Swamidas, J. V., Palmu, M., Duke, S. L., Mahantshetty, U., Nesvacil, N., Pötter, R. C., Nout, R. A., MS Radiotherapie, Cancer, Tan, L. T., Tanderup, K., Nappa, A., Petric, P., Jürgenliemk-Schulz, I. M., Serban, M., Swamidas, J. V., Palmu, M., Duke, S. L., Mahantshetty, U., Nesvacil, N., Pötter, R. C., and Nout, R. A.

Published
2021

50. Impact of transitioning to an online course - A report from the ESTRO gyn teaching course

Author

Tan, L T, Tanderup, K, Nappa, A, Petric, P, Jürgenliemk-Schulz, I M, Serban, M, Swamidas, J V, Palmu, M, Duke, S L, Mahantshetty, U, Nesvacil, N, Pötter, R C, Nout, R A, Tan, L T, Tanderup, K, Nappa, A, Petric, P, Jürgenliemk-Schulz, I M, Serban, M, Swamidas, J V, Palmu, M, Duke, S L, Mahantshetty, U, Nesvacil, N, Pötter, R C, and Nout, R A

Abstract

Introduction In 2020, the ESTRO course on image-guided radiotherapy and chemotherapy in gynaecological cancer was converted into an online version due to the COVID-19 pandemic. This paper describes the change process and evaluates the impact on participants compared with previous live courses. Methods and materials The 2019 live course contained 41 h of educational content, comprising 33 h of synchronous activities (lectures, interactive activities, videos) and 8 h of homework (contouring, dose planning). For the online course, the lectures were provided as pre-course material (11 mandatory, 22 optional). Contouring/dose planning homework was unchanged. The synchronous sessions were reconfigured as six 2-hour webinars (total educational content ~38 h).Participant numbers/characteristics, engagement and satisfaction for six live courses and the online course were compared. Results Participant numbers for the online and live courses were similar (90 vs. mean 96). There were more participants from outside Europe (28% vs. mean 18%) and more non-doctors (47% vs. mean 33%). Proportion of participants responding to the pre-course questionnaire was similar (77% vs. mean 78%) but post-course questionnaire response was lower (62% vs. mean 92%).43% participants viewed ≥75% of mandatory lectures before the webinars. 86% viewed the optional lectures. Submissions of contouring and dose planning homework was higher (contouring 77%-90% vs. 56%-69%, dose planning 74%-89% vs. 29%-57%).96% (47/49) participants rated the online course as Excellent (43%) or Good (53%). Overall satisfaction was similar (4.4 vs. mean 4.6). Conclusion Participant satisfaction and engagement with the online course remained high despite less contact time with faculty.

Published
2021

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