17 results on '"Pérez-Vicente J"'
Search Results
2. First Metatarsophalangeal Arthrodesis Fixation with an Intramedullary System
- Author
-
Álvarez, M. Concepción Castro, primary, Luque, Juan M. Morell, additional, Pérez, Vicente J. López, additional, González, Oscar Escudero, additional, García, Félix Castillo, additional, Andrade, Cristóbal Martínez, additional, and Zabala, Ibon López, additional
- Published
- 2016
- Full Text
- View/download PDF
3. A high-protein dietary treatment to intestinally hypotrophic rats induces ghrelin mRNA content and serum peptide level changes.
- Author
-
Vallejo-Cremades MT, Gómez de Segura IA, Gómez-García L, Pérez-Vicente J, and De Miguel E
- Abstract
BACKGROUND & AIMS: Ghrelin is a peptide mainly secreted in stomach with a potent growth hormone releasing activity both in vitro and in vivo. The trophic mucosal effect of an enriched protein diet may be related with ghrelin and growth hormone plasma levels since peptides from the somatotrophic axis are well-known trophic factors. The possible relationship between nutritionally regulated active ghrelin plasma levels and the intestinal trophic effects of a high-protein diet was probed in rats with intestinal hypotrophy induced by an elemental diet. METHODS: Normal and elemental-diet-induced intestinally hypotrophic rats were treated with either a normoproteic or a high-protein diet for 1 week. It was determined ghrelin and IGF-1 plasma levels, fundic and duodenal ghrelin concentrations, ghrelin mRNA content and intestinal morphometric, proliferative and apoptotic parameters were determined. Growth hormone plasma levels were measured indirectly through IGF-1 plasma levels. RESULTS: Ghrelin plasma levels increased in elemental diet-induced intestinally hypotrophic rats fed either diet. Duodenum mRNA content, but not fundus, increased under the same conditions where plasma was studied. Dietary treatment did not modify the IGF-1 plasma levels. However, animals previously fed an elemental diet to induce intestinal hypotrophy had significantly lower levels of IGF-1. CONCLUSIONS: The trophic effects on the intestine of an enriched protein diet are associated with increased ghrelin serum peptide level and mRNA content, and this increase might be related to the IGF-1 plasma levels in elemental diet-induced intestinally hypotrophic rats. [ABSTRACT FROM AUTHOR]
- Published
- 2005
4. Conversion to controlled-release levodopa/carbidopa treatment and quality of life as measured by the Nottingham Health Profile
- Author
-
Martínez-Martín, P., Grandas, F., Linazasoro, G., Bravo, J. L., Aguilar, M., Alías, M., Aparicio, M., Arbello, J. M., Balaguer, E., Beltrán, H. R., Bergaretxe, A., Cacho, A. J., Calopa, M., Cano, M., Carrillo, F., Ceballos, M. A., Cebrián, E., Cerdá, J., Coret, F., L Hotelerie, J. M., Díaz, C., Díez, M., Duarte, J., Durán, M. C., Fernández Carril, J. M., Fernández Herranz, M. R., Fernández, I., Flores Ruiz, J. J., González Maldonado, R., Granés, P., Hernández Gallego, J., Iriarte, L., Juni, J., Kulisevsky, J., Lezcano, E., López Del Val, J., López Pousa, S., Manaut, E., Martín Araguz, A., Martín, E., Martín, J., Mederer, S., Mikel, F., Morales, B., Muñoz Málaga, A., Muñoz, R., Olasagasti, B., Oterino, A., Pérez Sempere, A., Pérez Vicente, J. A., Piqueras, L., Pondal, M., Rey Del Corral, P., Ribacoba, R., Rodríguez, M., Rosich, M., Rubio, G., Sánchez Ortiz, C., Sanz, P., Taberner, P., Tapiador, M. J., Tordesillas, C., Ugarte, A., Vaamonde, J., Lydia Vela-Desojo, Vidal, M. J., Villanueva, P., Vivancos, F., Yánez, R., and Yusta, A.
5. Increased plasma levels of N-terminal pro-B-type natriuretic peptide as biomarker for the diagnosis of cardioembolic ischaemic stroke.
- Author
-
García-Carmona JA, Conesa-García E, Vidal-Mena D, González-Morales M, Ramos-Arenas V, Sánchez-Vizcaíno-Buendía C, Soria-Torrecillas JJ, Pérez-Vicente JA, and García-de-Guadiana-Romualdo L
- Subjects
- Humans, Female, Male, Aged, Prospective Studies, Middle Aged, Embolic Stroke blood, Embolic Stroke diagnosis, Aged, 80 and over, Prognosis, ROC Curve, Natriuretic Peptide, Brain blood, Peptide Fragments blood, Biomarkers blood, Ischemic Stroke blood, Ischemic Stroke diagnosis, Ischemic Stroke mortality, Ischemic Stroke complications
- Abstract
Background: Despite comprehensive study, the aetiology of stroke is not identified in 35% of cases., Aims: We conducted a study to assess the diagnostic capacity of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in the identification of ischaemic stroke of cardioembolic origin. The secondary purpose of the study was to evaluate the prognostic value of NT-proBNP for predicting 90-day all-cause mortality., Methods: We designed a prospective observational study including patients hospitalised due to stroke between March 2019 and March 2020. Blood samples were collected on admission to the emergency department and serum NT-proBNP levels were determined. Statistical analysis was performed using a bivariate logistic regression model and receiver operating characteristic (ROC) and Kaplan-Meier curves. Statistical significance was established at p<.05., Results: The study included 207 patients with first ischaemic stroke. Plasma NT-proBNP levels were significantly higher (p<.001) in the cardioembolic stroke group (2069pg/mL±488.5). ROC curves showed that NT-proBNP>499pg/mL was the optimum value for diagnosing cardioembolic ischaemic stroke (sensitivity, 82%; specificity, 80%). Moreover, plasma NT-proBNP levels>499pg/mL were independently associated with cardioembolic stroke (OR: 9.881; p=.001). Finally, NT-proBNP>1500pg/mL was useful for predicting 90-day mortality (sensitivity, 70%; specificity, 93%)., Conclusions: NT-proBNP was independently associated with cardioembolic stroke and should be quantified in blood tests within 24h of stroke onset. High plasma levels (>499pg/mL) may indicate an underlying cardioembolic cause, which should be further studied, while NT-proBNP >1500pg/mL was associated with increased 90-day mortality., (Copyright © 2021 Sociedad Española de Neurología. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
6. Adult rhombencephalosynapsis: an unusual presentation of an infrequent entity.
- Author
-
Sánchez-Villalobos JM, Torres-Perales AM, Serrano-Velasco L, and Pérez-Vicente JA
- Subjects
- Adult, Cerebellum, Humans, Anencephaly, Cerebellar Diseases
- Published
- 2021
- Full Text
- View/download PDF
7. Adult rhombencephalosynapsis: An unusual presentation of an infrequent entity.
- Author
-
Sánchez-Villalobos JM, Torres-Perales AM, Serrano-Velasco L, and Pérez-Vicente JA
- Published
- 2020
- Full Text
- View/download PDF
8. A high-protein dietary treatment to intestinally hypotrophic rats induces ghrelin mRNA content and serum peptide level changes.
- Author
-
Teresa Vallejo-Cremades M, Gómez de Segura IA, Gómez-García L, Pérez-Vicente J, and De Miguel E
- Subjects
- Animals, Dietary Proteins administration & dosage, Duodenum anatomy & histology, Duodenum drug effects, Duodenum metabolism, Gastric Fundus anatomy & histology, Gastric Fundus drug effects, Gastric Fundus metabolism, Gene Expression Regulation drug effects, Ghrelin, Growth Hormone blood, Immunohistochemistry, Intestinal Mucosa anatomy & histology, Intestinal Mucosa metabolism, Intestinal Mucosa pathology, Peptide Hormones blood, RNA, Messenger metabolism, Random Allocation, Rats, Rats, Wistar, Reverse Transcriptase Polymerase Chain Reaction, Dietary Proteins therapeutic use, Insulin-Like Growth Factor I metabolism, Intestinal Mucosa drug effects, Peptide Hormones metabolism
- Abstract
Background & Aims: Ghrelin is a peptide mainly secreted in stomach with a potent growth hormone releasing activity both in vitro and in vivo. The trophic mucosal effect of an enriched protein diet may be related with ghrelin and growth hormone plasma levels since peptides from the somatotrophic axis are well-known trophic factors. The possible relationship between nutritionally regulated active ghrelin plasma levels and the intestinal trophic effects of a high-protein diet was probed in rats with intestinal hypotrophy induced by an elemental diet., Methods: Normal and elemental-diet-induced intestinally hypotrophic rats were treated with either a normoproteic or a high-protein diet for 1 week. It was determined ghrelin and IGF-1 plasma levels, fundic and duodenal ghrelin concentrations, ghrelin mRNA content and intestinal morphometric, proliferative and apoptotic parameters were determined. Growth hormone plasma levels were measured indirectly through IGF-1 plasma levels., Results: Ghrelin plasma levels increased in elemental diet-induced intestinally hypotrophic rats fed either diet. Duodenum mRNA content, but not fundus, increased under the same conditions where plasma was studied. Dietary treatment did not modify the IGF-1 plasma levels. However, animals previously fed an elemental diet to induce intestinal hypotrophy had significantly lower levels of IGF-1., Conclusions: The trophic effects on the intestine of an enriched protein diet are associated with increased ghrelin serum peptide level and mRNA content, and this increase might be related to the IGF-1 plasma levels in elemental diet-induced intestinally hypotrophic rats.
- Published
- 2005
- Full Text
- View/download PDF
9. [Ischemic cerebral infarction due to factor V Leiden, hereditary spherocytosis and smoking].
- Author
-
Monge-Argilés JA, López-García MD, Ortega-Ortega MD, Kahn-Mesía EI, Pérez-Vicente JA, Morales-Ortiz A, and Bautista-Prados J
- Subjects
- Adult, Humans, Male, Risk Factors, Tomography, X-Ray Computed, Brain Ischemia etiology, Brain Ischemia pathology, Brain Ischemia physiopathology, Cerebral Infarction etiology, Cerebral Infarction pathology, Cerebral Infarction physiopathology, Factor V, Smoking adverse effects, Spherocytosis, Hereditary complications
- Published
- 2005
10. [Megadolicobasilar, ulcerative colitis and ischemic stroke].
- Author
-
Monge Argiles JA, Bautista Prados J, Ortega Ortega MD, Pérez Vicente JA, and Morales Ortiz A
- Subjects
- Cerebral Angiography, Humans, Male, Middle Aged, Platelet Aggregation Inhibitors therapeutic use, Vertebrobasilar Insufficiency drug therapy, Brain Ischemia complications, Colitis, Ulcerative complications, Vertebrobasilar Insufficiency complications, Vertebrobasilar Insufficiency diagnosis
- Abstract
Megadolichobasilar (MDB) is a rare arterial anomaly consisting of excessive elongation, widening and tortuosity of the basilar artery. It may be associated with different neurological disturbances, including cerebral ischemic stroke, compression of the cranial nerves, hydrocephalus, headache and vertigo. Ulcerative colitis (UC) is an inflammatory bowel disease of unknown aetiology which may be complicated by arterial or venous cerebral illness, among others neurological anomalies. We report a patient suffering from UC who presented ischemic stroke. The neurorradiological studies showed incompletely thrombosed MDB accompanied by a distal aneurysm from narrow zone. These findings advised anticoagulant treatment which leads to neurological stability. To our knowledge, it is the first report of MDB associated with UC. Although this association is probably fortuitous, we discuss both the etiopatogeny and the possibly influence of each one on the clinical picture.
- Published
- 2003
11. [Aetiological diagnosis of cerebral infarction in a county hospital].
- Author
-
Morales A, Morera-Guitart J, Bautista-Prados J, Clar C, Herruzo E, Mas G, Monge-Argiles JA, Ortega-Ortega MD, Pérez-Vicente JA, and Sendra JC
- Subjects
- Aged, Cerebral Infarction pathology, Female, Humans, Male, Middle Aged, Risk Factors, Spain, Cerebral Infarction diagnosis, Cerebral Infarction etiology, Hospitals, County standards
- Abstract
Introduction: Cerebral infarction (CI) can be classified aetiologically in several different ways using explicit diagnostic criteria. However, the extent to which these diagnostic criteria are actually implemented in clinical practice is unknown. Aims. The aim of this study was to analyse the management and use of diagnostic tests in the aetiological diagnosis of CI in two county hospitals and to compare this with the most common recommendations. We also sought to analyse the clinical and demographic variables that may help to explain why these guidelines are not followed., Patients and Methods: We reviewed the discharge abstracts of 307 cases of CI attended in two county hospitals between 1999 and 2000 and we analysed the clinical data, diagnostic tests and the final diagnosis. The diagnoses were reorganised using the TOAST, Laussane, NINDS and SEN 98 classifications and we analysed the frequency with which the diagnostic tests were employed in each aetiological subtype., Results: Average age: 71.3 years; 59.3% were males. CAT scans were performed in 97.1% of cases, neurosonology was used in 40.1% and echocardiography was performed in 8.5%. The aetiological diagnosis was: atherothrombotic 22.4%, cardioembolic 10.7%, lacunar 26%, unusual causes 0.3% and unknown causes 1.6%. In 37.4% of cases the diagnosis was given as unspecified CI. On reclassifying the diagnoses according to SEN 98 criteria, we obtained the following: atherothrombotic 19.5%, cardioembolic 2.8%, lacunar 13.7% and of unknown origin 63.5%. 0.6% of the cases were unclassifiable. Factors that exerted an influence on the fact that diagnostic tests were less frequently carried out included age, level of awareness and mortality. The most frequent cause of incomplete studies was the absence of carotid Doppler., Conclusions: The guidelines for aetiological diagnosis of CI are not often followed. Systematic performance of a neurosonological study would improve aetiological diagnosis of CI.
- Published
- 2003
12. [Controversies in the evaluation of asymptomatic microhematuria].
- Author
-
López Cubillana P, Prieto González A, Server Pastor G, Torralba JA, Gómez Gómez G, Guardiola Mas A, Martínez Pertusa P, García Hernández JA, Bañón Pérez VJ, Valdelvira Nadal P, Cao Avellaneda E, Asensio Egea L, and Pérez Albacete M
- Subjects
- Calcium urine, Cystoscopy, Hematuria epidemiology, Hematuria etiology, Humans, Kidney Diseases complications, Kidney Diseases diagnosis, Kidney Diseases epidemiology, Prospective Studies, Spain epidemiology, Uric Acid urine, Urography, Hematuria diagnosis
- Abstract
Objective: Asymptomatic microhematuria continues to be a problem. It has a prevalence of 16% and numerous conditions can present this clinical manifestation., Methods: A prospective study was carried out on all patients that consulted at the urological services during 2000 for asymptomatic hematuria. Patients presenting with irritative symptoms, urethral secretion, perineal or suprapubic pain, urinary tract infections, renal lithiasis or history of trauma were not included in the study., Results: None of the patients presented tumors. Two patients presented renal lithiasis, 5 simple renal cysts, 8 hypercalciuria and 3 hyperuricosuria. None of the 11 patients with hypercalciuria or hyperuricosuria had a history of lithiasis., Conclusions: Although the size of the study is small, the incidence of tumors in patients with asymptomatic microhematuria appears to be far from the 12.5% incidence reported by some authors and might probably be closer to the 0.5% incidence reported by others. Furthermore, the significant pathology (renal lithiasis), which requires treatment, is also infrequent.
- Published
- 2002
13. [Fever of central origin during stroke].
- Author
-
Morales-Ortiz A, Jiménez-Pascual M, Pérez-Vicente JA, Monge-Arguiles A, and Bautista-Prados J
- Subjects
- Aged, Analgesics, Non-Narcotic therapeutic use, Brain physiopathology, Diagnosis, Differential, Female, Fever diagnosis, Fever drug therapy, Fever physiopathology, Humans, Infections complications, Infections physiopathology, Male, Prospective Studies, Respiratory Tract Infections complications, Respiratory Tract Infections physiopathology, Stroke physiopathology, Treatment Failure, Urinary Tract Infections complications, Urinary Tract Infections physiopathology, Fever etiology, Stroke complications
- Abstract
Introduction: Fever appears in a fourth of stroke, approximately. Its origins, (the most of them are infectious) are unknown in a minority of the cases. Some hypotheses indicate that central mechanisms like hypothalamic lesions or segregation of endogenous pyrogens may be implicated., Objective: To evaluate the frequency of central fever during stroke and to notice if there are clinical differences between infectious and central origins of the fever., Patients and Methods: 103 patients were evaluated prospectively, if someone had fever, an investigation about an infectious origin was made. We divided the fever patients into two groups: "infectious fever" and "fever without infection documented" and we analyzed the clinical differences between them., Results: 23% of the patients had fever, 33% without infection documented. This last group had earlier fevers. They had more clinical severity and more mortality. The fever was higher and it didn't response to the antipyretic treatment also. The others parameters didn't show any difference between the two groups., Conclusion: The patients with fever without infection documented ( probably fever of central origin)had a defined model with its own characteristics, in a different way from infectious fever.
- Published
- 2001
14. [Kinesigenic paroxysmal choreoathetosis: contribution of SPECT].
- Author
-
Monge-Argilés J, Bautista-Prados J, Pérez-Vicente J, and Morales-Ortiz A
- Subjects
- Adolescent, Adult, Humans, Male, Athetosis complications, Athetosis diagnostic imaging, Chorea complications, Chorea diagnostic imaging, Epilepsy complications, Epilepsy diagnostic imaging, Tomography, Emission-Computed, Single-Photon
- Abstract
We report two unrelated patients affected of kinesigenic paroxysmal choreoathetosis (CPC), during a symptomatic period. Routine complementary exams were normal. The 99mTc-HMPAO cerebral SPECT showed hyperactivation in the basal ganglia opposite to the choreoathetosic symptoms and reduced untake in the near parietal and subcortical zones in one case. These observations suggest that abnormal hyperactivity of contralateral basal ganglia may cause choreathetotic movements in patients with CPC.
- Published
- 2001
15. Brainstem lesions decrease heart rate variability.
- Author
-
Monge Argilés JA, Palacios Ortega F, Vila Sobrino JA, Bautista Prados J, Pérez Vicente JA, Morales Ortiz A, and Palao Sánchez A
- Subjects
- Adult, Female, Heart Diseases diagnosis, Humans, Magnetic Resonance Imaging, Male, Prospective Studies, Time Factors, Tomography, X-Ray Computed, Brain Diseases complications, Brain Diseases diagnosis, Brain Stem diagnostic imaging, Brain Stem pathology, Heart Diseases etiology, Heart Rate physiology
- Abstract
Objective: Brainstem is an essential region in the regulation of the autonomic cardiovascular functions. Some authors have reported that medulla oblongata is very important in this regulation, but probably is not the unique because the sympathetic cardiovascular centers are spread in the brainstem. Since some years ago, we are able to measure heart rate variability which is a useful tool for assessing quantitatively both sympathetic and parasympathetic autonomic effects on the heart. The objective is to evaluate the effects of isolated brainstem lesion (IBL) on sympathetic and parasympathetic cardiovascular regulatory functions., Patients and Methods: We analyzed the heart rate variability in time and frequency domains in 14 IBL patients and 25 age and sex matched healthy control subjects, measured from 24-h electrocardiogram., Results: Low frequency power (0.001) and low frequency/high frequency power (0.05) were significantly higher in control subjects independently, all together or in subgroups (medulla oblongata affected or not). High frequency power (0.05) were higher too in control subjects. Variability in time domain (0.001 and 0.01) was lower when the medulla oblongata was affected., Conclusions: These results confirm that brainstem lesions cause cardiovascular autonomic dysregulation overall when the medulla oblongata is affected. The importance of this region in parasympathetic and sympathetic cardiovascular functions is showed. However, pontine and mesencephalic lesions seem to provoke a decrease only in sympathetic regulation.
- Published
- 2000
16. [Facioscapulohumeral inflammatory myopathy: long-term prognosis and nosologic characterization].
- Author
-
Pérez Vicente JA, Mateo D, Esteban A, and Giménez-Roldán S
- Subjects
- Arm, Biopsy, Child, Facial Muscles, Family Health, Female, Humans, Muscular Dystrophies genetics, Muscular Dystrophies pathology, Myositis genetics, Myositis pathology, Prognosis, Shoulder, Time Factors, Muscular Dystrophies physiopathology, Myositis physiopathology
- Published
- 1987
17. [Generalized cortical (Van Buchem) hyperostosis].
- Author
-
Rodríguez de Castro E, Pérez Vicente JA, Lafuente J, and Giménez-Roldán S
- Subjects
- Empty Sella Syndrome etiology, Epiphyses pathology, Humans, Osteochondrodysplasias complications, Prognosis, Osteochondrodysplasias diagnosis
- Published
- 1986
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.