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The catalogue are only available at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/cat/J/A+A/647/A89 Context. The morphology of galaxies provide us with a unique tool for relating and understanding other physical properties and their changes over the course of cosmic time. It is only recently that we have been afforded access to a wealth of data for an unprecedented number galaxies thanks to large and deep surveys. Aims. We present the morphological catalogue of the OTELO survey galaxies detected with the Hubble Space Telescope (HST)-ACS F814W images. We explore various methods applied in previous works to separate early-type (ET) and late-type (LT) galaxies classified via spectral energy distribution (SED) fittings using galaxy templates. Together with this article, we are releasing a catalogue containing the main morphological parameters in the F606W and F814W bands derived for more than 8000 sources. Methods. The morphological analysis is based on the single-Sérsic profile fit. We used the GALAPAGOS2 software to provide multi-wavelength morphological parameters fitted simultaneously in two HST-ACS bands. The GALAPAGOS2 software detects, prepares guess values for GALFIT-M, and provides the best-fitting single-Sérsic model in both bands for each source. Stellar masses were estimated using synthetic rest-frame magnitudes recovered from SED fittings of galaxy templates. The morphological catalogue is complemented with concentration indexes from a separate SExtractor dual, high dynamical range mode. Results. A total of 8812 sources were successfully fitted with single-Sérsic profiles. The analysis of a carefully selected sample of ∼3000 sources up to zphot = 2 is presented in this work, of which 873 sources were not detected in previous studies. We found no statistical evidence for the evolution of the low-mass end of mass–size relation for ET and LT since z = 2. Furthermore, we found a good agreement for the median size evolution for ET and LT galaxies, for a given stellar mass, with the data from the literature. Compared to previous works on faint field galaxies, we found similarities regarding their rest-frame colours as well as the Sérsic and concentration indices. This work was supported by the project Evolution of Galaxies, of reference AYA2014-58861-C3-1-P and AYA2017-88007-C3-1-P, within the "Programa estatal de fomento de la investigacion cientifica y tecnica de excelencia del Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion (2013-2016)" of the "Agencia Estatal de Investigacion del Ministerio de Ciencia, Innovacion y Universidades", and co-financed by the FEDER "Fondo Europeo de Desarrollo Regional". APG, RPM and MSP was supported by AYA2017-88007-C3-2-P. APG and MC are also supported by the Spanish State Research Agency grant MDM-2017-0737 (Unidad de Excelencia Maria de Maeztu CAB). JAD is grateful for the support from the UNAM-DGAPA-PASPA 2019 program, and the kind hospitality of the IAC. Based on observations made with the Gran Telescopio Canarias (GTC), installed in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias, on the island of La Palma. This paper made use of the IAC Supercomputing facility HTCondor (http://research.cs.wisc.edu/htcondor/). This paper made use of the Wright (2006) cosmological calculator. Based on observations obtained with MegaPrime/MegaCam, a joint project of CFHT and CEA/IRFU, at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council (NRC) of Canada, the Institut National des Science de l'Univers of the Centre National de la Recherche Scientifique (CNRS) of France, and the University of Hawaii. This work is based in part on data products produced at Terapix available at the Canadian Astronomy Data Centre as part of the Canada-France-Hawaii Telescope Legacy Survey, a collaborative project of NRC and CNRS. M.A.L.L. is a DARK-Carlsberg Foundation Fellow (Semper Ardens project CF15-0384). MP acknowledges financial financial support from the Ethiopian Space Science and Technology Institute (ESSTI) under the Ethiopian Ministry of Innovation and Technology (MInT), and of the Spanish MEC undergrant AYA2016-76682-C3-1-P and PID2019-106027GB-C41 and financial support from the State Agency for Research of the Spanish MCIU through the "Center of Excellence Severo Ochoa" award to the Instituto de Astrofisica de Andaluca (SEV-2017-0709). Peerreview

Betelgeuse is a cool star of spectral type M and luminosity class I. In the present work, the activity cycle of Betelgeuse was obtained from the integrated emission flux of the Mg II H and K lines, using more than 250 spectra taken from the International Ultraviolet Explorer (IUE) online database. Of which it was found, based on a Lomb Scargle periodogram, a cycle of 16 years, along with 2 sub-cycles with a period of the order of 0.60 and 0.65 years, which may be due to turbulence or possible stellar flares. In addition, an analysis of line asymmetry was made by means of the chromospheric emission line bisectors, due to the strong self-absorption observed in this lines, the blue and red wings were analyzed independently. In order to measure such asymmetry, a “line shift” was calculated, from which several cycles of variability were obtained from a Lomb Scargle periodogram, spanning from few months to 4 years. In the sense, the most significant cycle is about 0.44 and 0.33 years in the blue and red wing respectively. It is worth noting, that the rotation period of the star doesn’t play an important role in the variability of the Mg II lines. This technique provides us with a new way to study activity cycles of evolved stars.

EL biogas es un portador energético procedente de la digestión anaeróbica de residuos orgánicos de distinto origen. Puede utilizarse para la producción combinada de calor y vapor en procesos industriales. Asimismo, se plantean otras aplicaciones innovadoras como combustible para vehículos y pilas combustible, así como su integración en las redes actuales de gas natural.

La Unidad de Inteligencia y Prospectiva del CIEMAT y la Fundación OPTI realizaron un estudio sobre tecnologías renovables dentro del Programa de Prospectiva Tecnológica 1998 - 2001. Cinco años después, se evaluó el desarrollo de las tendencias, los cambios y sus posibles causas. Pasados diez años, la evolución del sector justifica este nuevo estudio para identificar factores emergentes, riesgos y oportunidades en función de las capacidades existentes.

Se estudió la población de células cebadas (CC) presentes en sacos anales de perros adultos y seniles mediante su conteo en cortes de tejido procesado con la técnica de inclusión en parafina y teñidos con azul de toluidina. El promedio de CC obtenido para el grupo de perros adultos jóvenes fue de 18,16 ± 7,58 (n=12 perros) y para el grupos de adultos maduros fue de 73,75 ± 16,29 (n=12 perros). Al comparar el número de células de ambos grupos con la prueba de U Mann-Withney se encontró que son significativamente diferentes (P< 0,0001), siendo mayor en el grupo de perros seniles. Esta mayor población de CC puede estar relacionada con una mayor susceptibilidad de los perros seniles a reacciones inflamatorias del tejido de los sacos anales causadas por cambios en la dieta, obesidad y diarrea crónica. We studied the population of mast cells (CC) present in anal sacs of adult and senile dogs by its count in tissue processed with the technique of embedding in paraffin and stained with toluidine blue. The average CC obtained for the group of adult dogs (n=12) was 18.16 ± 7.58 and for group of senile dogs (n=12) was 73.75 ± 16.29. When comparing the number of cells in both groups with Mann-Whitney U test were found to be significantly different (P0.0001), being higher in the group of senile dogs. The largest population of CC may be related to an increased susceptibility of senile dogs to inflammatory reactions in the tissue of the anal sacs caused by changes in diet, obesity and chronic diarrhea.

Composite laminates offer decisive advantages compared to more traditional materials, especially in structural applications where weight is a design-limiting factor. However, they have also shown a susceptibility to impact damage due to the lack of plastic deformation, the low transverse and interlaminar shear strength and the laminar construction to compensate the anisotropic nature of plies. Low-velocity impacts induce a significant internal damage to laminates, causing severe reductions on stiffness, compression strength and structural stability of the structure. Consequently, there is a need to develop methodologies and tools for inspection to allow early detection of structural degradation, in order to prevent premature failure or collapse. Damage detection techniques based on structural dynamic response are presented as an attractive alternative to traditional assessment techniques, among others, because for dynamic response measurement a finite number of reference points are needed. Since there is no need to fully access the structure, it can be monitored with no service interruption. The techniques are based upon the relationship between the modal parameters and the physical properties of the structure, assuming that changes occurred in these properties induced by damage cause measurable variations of the modal parameters. This thesis analyzes the feasibility of using experimental and numerical techniques based on the dynamic response for the detection and location of induced damage, for quantifying the degree of severity and predicting the residual mechanical properties of composite laminates plates after being subjected to a low-velocity impact test. This research presents a mixed experimental and numerical approach. On the one hand there is a rigorous experimental study that includes the evaluation of the impact damage resistance, the induced damage characterization, the quantification of the effects on the dynamic response and the evaluation of residual bearing capacity. The experimental study is completed with a detailed analysis of the effect induced by artificial delaminations in the dynamic response and the residual bearing capacity of laminates. On the other hand, the phenomenon has been simulated mainly by estimating the initiation and propagation of interlaminar damage and equally the induced effects in the dynamic response. As per the numerical approach, composite material is treated as a microstructure in which failure occurs in the interaction among the constituent materials. To reproduce material’s degradation a strategy of localized elastic stiffness reduction has been used, which does not require intervention during the pre-processing phase. Empirical results provide important conclusions concerning the degree of sensitivity and suitability of different modal correlation criteria for the identification of an impact-induced damage. The new correlation criteria defined and the analysis of static and dynamic residual properties have allowed to narrow the range of uncertainty and reduce the current limitation on the maximum allowable compressive deformation of the laminates. The computational tool developed allows simulating the vibrational behavior of composite laminates, defining the material and its state of degradation in the microscale. The results support the feasibility of the microstructural approach to simulate the phenomenon., Los materiales compuestos laminados ofrecen ventajas determinantes en comparación con los materiales más tradicionales, especialmente en aplicaciones estructurales donde el peso es un factor limitante de diseño. Sin embargo, éstos también han demostrado una susceptibilidad al daño por impacto debido a la carencia de deformación plástica, a la baja resistencia transversal e interlaminar y a la construcción laminada para reducir la naturaleza anisótropa del material. Los impactos a baja velocidad inducen en los laminados un daño interno que provoca reducciones severas en la rigidez, en la resistencia y en la estabilidad estructural. Consecuentemente, se presenta la necesidad de desarrollar metodologías y herramientas de inspección que permitan una detección precoz del estado de degradación estructural, con el fin de prevenir fallos o colapsos prematuros. Las técnicas de detección de daño basadas en la respuesta dinámica estructural se presentan como una atractiva alternativa a las técnicas de evaluación tradicionales, entre otros, porque para la adquisición de la respuesta dinámica se requiere un número finito de puntos de referencia, por lo que no es necesario un acceso completo a la estructura, permitiendo la monitorización incluso sin interrupción del servicio. Las técnicas se fundamentan en la relación entre los parámetros modales y las propiedades físicas de la estructura, asumiendo que los cambios en dichas propiedades inducidos por el daño, originan variaciones cuantificables de los parámetros modales. En esta tesis se analiza la viabilidad del uso de las técnicas experimentales y numéricas basadas en la respuesta dinámica, para la detección y localización del daño inducido, la cuantificación del grado de severidad y la predicción de las propiedades mecánicas residuales de laminados de material compuesto tras ser sometidos a un impacto a baja velocidad. El trabajo de investigación comprende un enfoque mixto experimental y numérico. Por un lado constituye un riguroso estudio experimental que incluye la evaluación de la resistencia a impacto, la caracterización del daño inducido, la cuantificación de los efectos en la respuesta dinámica y la evaluación de la capacidad portante residual. El estudio experimental se completa con un minucioso análisis del efecto inducido por deslaminaciones artificiales en la respuesta dinámica y en la capacidad portante residual de los laminados. Por otro lado, se ha simulado el fenómeno estimando principalmente la iniciación y la propagación del daño interlaminar e igualmente los efectos inducidos en la respuesta dinámica. En el enfoque numérico se trata el material compuesto como un sistema microestructural, en el cual los fallos surgen en la interacción entre los materiales constituyentes. Para reproducir la degradación se emplea una estrategia de reducción localizada de la rigidez elástica del material que no demanda una intervención durante el preproceso. Los resultados empíricos aportan conclusiones relevantes en relación al grado de sensibilidad y a la adecuación de los diferentes criterios de correlación modal para la identificación del daño inducido por un impacto. Los nuevos criterios de correlación definidos y el análisis conjunto de las propiedades estáticas y dinámicas residuales, han permitido acotar el intervalo de incertidumbre y reducir la limitación actual en relación a la deformación máxima admisible a compresión de los laminados. La herramienta de cálculo desarrollada permite simular el comportamiento vibratorio de laminados compuestos definiendo el material y su estado de degradación en la microescala. Los resultados corroboran la viabilidad del enfoque microestructural para la simulación del fenómeno.

During immunologic synapse (IS) formation, human CD38 redistributes to the contact area of T cell-antigen-presenting cell (APC) conjugates in an antigen- dependent manner. Confocal microscopy showed that CD38 preferentially accumulated along the contact zone, whereas CD3-ζ redistributed toward the central zone of the IS. APC conjugates with human T cells or B cells transiently expressing CD38-green fluorescent protein revealed the presence of 2 distinct pools of CD38, one localized at the cell membrane and the other in recycling endosomes. Both pools were recruited to the T/APC contact sites and required antigen-pulsed APCs. The process appeared more efficient in T cells than in APCs. CD38 was actively recruited at the IS of T cells by means of Lck-mediated signals. Overex- pression of CD38 in T cells increased the levels of antigen-induced intracellular calcium release. Opposite results were obtained by down-regulating surface CD38 expression by means of CD38 siRNA. CD38 blockade in influenza HA-specific T cells inhibited IL-2 and IFN-γ production, PKCe phosphorylation at Thr538, and PKC6 recruitment to the IS induced by antigen-pulsed APCs. These results reveal a new role for CD38 in modulating antigen-mediated T-cell responses during IS formation. © 2008 by The American Society of Hematology., This work was supported by grants from the Ministerio de Educación y Ciencia (MEC; SAF2002-00721, and SAF2005-06056-C02-01 to J.S.), the Consejería de Innovación, Ciencia y Empresa de la Junta de Andalucía (P05-CVI-00908 to J.S.), the Instituto Carlos III-FIS, Ministerio de Sanidad y Consumo (FIS03/0389 and FIS06/1502 to M.Z.), and by grants from the Italian Association for Cancer Research (AIRC), FIRMS, and MIUR (to F.M.). Centro Nacional de Investigaciones Cardiovasculares (CNIC) is supported by the Spanish Ministry of Health and Consumer Affairs and the Pro-CNIC Foundation. M.Z. was supported by a Ramón y Cajal contract from MEC. P.M. was supported by a FPI Fellowship from MEC. P.M. was a PhD candidate at University of Granada (Spain), and this work was submitted in partial fulfillment of the requirement for the PhD.

Los fitoestrógenos son substancias de origen vegetal con propiedades similares a los estrógenos. Se han identificado diferentes grupos de fitoestrógenos entre los que destacan las isoflavonas como la genisteina, los coumestanos como el coumestrol, y los lignanos representados por la enterolactona. Estos compuestos actúan como agonistas o como antagonistas de las hormonas esteroidales dependiendo de la dosis que se utilice. Esta acción aparentemente contradictoria se debe a su capacidad para unirse como ligandos a los receptores estrogénicos alfa (ERα) del útero, glándula mamaria, sistema cardiovascular y hueso, y con mayor afinidad a los receptores estrogénicos beta (ERβ) presentes en próstata, ovarios, testículos, tracto urinario, tejido linfoide y algunas regiones del cerebro como el hipotálamo. Se ha observado que a medida que se incrementa la dosis de genisteína y coumestrol, se inducen folículos hemorrágicos, abortos, síndrome estrogénico, y supresión de picos de hormona luteinizante (LH) en las hembras, mientras que en los machos se altera el desarrollo testicular y disminuye el recuento de espermatozoides. En esta revisión se presenta un panorama del estado actual de las investigaciones respecto a las implicaciones de los fitoestrógenos sobre la reproducción y sus perspectivas de estudio, poniendo énfasis en su importancia en los animales domésticos Phytoestrogens are plant-derived compounds having similar effects to estrogens. Several phytostrogen groups have been identified being the most characteristics the isoflavones like genistein, coumestans like coumestrol, and lignans represented by the enterolactone. Depending on the doses, they can act as agonists or antagonists of steroidal hormones. This apparently bimodal function is due to their capacity to interact with the alpha form of the estrogen receptor (ERα) in several organs of the female reproductive tract and to the beta form ERβ present in prostate, testis, ovaries, limph nodes and brain regions. It has been observed that an increase in genistein or coumestrol induces an increase in haemorrhagic follicles, miscarriages, LH-FSH surge suppression and even estrogenic syndrome, whereas in males, induces alterations in testis development and a decrease in sperm count. In this review, a panoramic view of the actual research of phytostrogen impact on the reproductive function and perspectives mainly for domestic animals is presented

The interest in using bio-materials in pavement engineering has grown significantly over the last decades due to environmental concerns about the use of non-recoverable natural resources. In this paper, bio-materials are used together with Reclaimed Asphalt (RA) to restore some of the properties of the aged bitumen present in mixtures with high RA content. For this purpose, two bio-materials are studied and compared to conventional and polymer modified bitumens. Blends of these materials with RA bitumen were produced and studied to simulate a 50% RA mixture. The rejuvenating effect of the two bio-materials on RA has been assessed and compared with the effect of the conventional binders. Apparent Molecular Weight Distribution of the samples (obtained by the ?-method) and different rheological parameters were used for this purpose. Results revealed the power of bio-materials to rejuvenate RA bitumen, showing their capability to be used as fresh binders in high-RA content mixtures., El interés en la utilización de bio-materiales en ingeniería de pavimentos ha crecido significantemente en las últimas décadas debido a la conciencia ambiental sobre el uso de recursos naturales no renovables. En este artículo, se utilizan bio-materiales para recuperar las propiedades iniciales del betún envejecido presente en mezclas con alto contenido de asfalto reciclado (RA). Para ello, se ha estudiado y comparado el comportamiento de dos bio-materiales con betunes convencionales y betunes modificados con polímeros. Con este objetivo, se fabricaron mezclas de bio-materiales y betún reciclado simulando mezclas asfálticas con 50% de contenido de reciclado. El efecto rejuvenecedor de los bio-materiales se ha evaluado y comparado con el efecto rejuvenecedor de ligantes convencionales mediante el cálculo de las distribuciones de peso molecular aparente y diferentes parámetro reológicos. Los resultados muestran el poder rejuvenecedor de los bio-materiales, poniendo de manifiesto su potencial para usarse como ligantes vírgenes en mezclas asfálticas con alto contenido de reciclado.