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Byline: Cuneyt Turan (1,2), Musa Ozdemir (2) Keywords: Short bowel syndrome; Intestinal plication; Intestinal transit time Abstract: Short bowel syndrome (SBS) can occur after extensive intestinal resections. In SBS, the aim of surgical techniques is to prolong intestinal transit time (ITT) and to increase the absorptive surface. This experimental study was conducted to research the effect of extramucosal intestinal plication on ITT in rats. Thirty Sprague-Dawley rats were divided into three groups. In the control group, barium solution was administrated by gavage. Forty-five minutes later, the rats were sacrificed, and the total length of their small bowels (SBs) and the distance of the barium in the SBs were measured. The ratio of the distance of the barium to the length of the SB was calculated, and the ITT was found for normal rats. Intestinal plication (made with three seromuscular sutures at the same level: one on the antimesenteric side, and two on the lateral sides of the bowel) and laparotomy and bowel manipulation were carried out in the study and sham groups, respectively, and ITT was measured by the same method after 1 week. A one-way ANOVA test was used to compare the groups in terms of body weight, total length of the SB, distance of the barium in the SB, and the ratio of this distance to the length of the SB. The rats were statistically homogeneous in terms of body weight and total length of the SB ( p &gt 0.05). The distances of the barium in the small bowel in the control, sham, and study groups were 73.4+-8.5 cm, 77.5+-6.8 cm, and 56.3+-3.6 cm, respectively. The distances of barium in the SB in the study group were statistically shorter than in the other groups ( p &lt 0.05). The ratios of the distance of the barium to the length of the SB in the control, sham, and study groups were 65.8+-7.3, 66.4+-4.5, and 49.9+-3.8, respectively. In the study group, this ratio was also statistically lower than in the other groups ( p &lt 0.05). Extramucosal intestinal plication retarded ITT significantly in the study group compared with the other groups. This technique does not entail any risk of morbidity and mortality therefore, it can be used in the treatment of SBS. Author Affiliation: (1) Cocuk Cerrahisi Anabilim DalA+-, Erciyes Universitesi TA+-p Fakultesi, 38039, Kayseri, Turkiye (2) Department of Pediatric Surgery, Erciyes University, 38039 , Kayseri, Turkey Article History: Registration Date: 03/02/2004 Accepted Date: 17/10/2003 Online Date: 13/05/2004 Article note: Presented at XX Annual Meeting of Turkish Association of Pediatric Surgeons, 15--19 October 2002, Mersin, Turkey.

Byline: Cuneyt Turan (1), Ugur Ozkan (1), Bulent Hayri Ozokutan (1), Musa Ozdemir (1), Hamit Okur (1), Mustafa KucukaydA+-n (1) Keywords: Key wordsaCorrosive esophageal injury; Benzalkonium chloride; Trichloracetic acid; Newborn Abstract: aTo evaluate the morbidity and mortality of corrosive esophageal injuries (CEI) in the neonatal period, the records of 184 children hospitalized following caustic ingestion over a 10-year period from January 1987 to November 1997 were reviewed. Eight (4.3%) were newborns (5 boys and 3 girls). The mean age of the newborns was 12 days (range 1--28). The ingested caustic materials were benzalkonium chloride in six patients and trichloroacetic acid in two. Oropharyngeal examination and esophagoscopy were performed for diagnosis. Hyperemia and fibrin plaques were present in the oropharynx in all patients. The management consisted of endotracheal intubation, antibiotics, corticosteroids, and total parenteral nutrition. Pneumonia and sepsis developed in three patients and one died of sepsis. Stenosis developed in two patients, who were treated three times with antegrade dilatations. The morbidity was 62.5% (five patients) and the mortality was 12.5% (one) in newborns with CEI. These results indicate that ingestion of a caustic substance results in high morbidity and mortality in newborns. Parents and nurses should be warned about this risk. Author Affiliation: (1) Department of Pediatric Surgery, Faculty of Medicine, Erciyes University, 38039, Kayseri, Turkey, TR (2) Erciyes Universitesi TA+-p Fakultesi, Cocuk Cerrahisi Anabilim DalA+-, Kayseri 38039, Turkey, TR Article note: Accepted: 11 January 2000