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27 results on '"Ozbagcivan, Ozlem"'

11. Xerosis cutis and associated co-factors in women with prurigo nodularis

Author

Akarsu, Sevgi, Ozbagcivan, Ozlem, Ilknur, Turna, Semiz, Fatma, Inci, Burcu Bahar, and Fetil, Emel

Subjects
Adult, Male, medicine.medical_specialty, Cutis, Dermatology, Young Adult, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Prurigo, Diabetes mellitus, medicine, Humans, Psychogenic disease, Age of Onset, Young adult, Retrospective Studies, Investigation, business.industry, Pruritus, Ichthyosis, Retrospective cohort study, General Medicine, Middle Aged, medicine.disease, Dermatitis, atopic, 030220 oncology & carcinogenesis, RL1-803, Female, Age of onset, business, Prurigo nodularis
Abstract

Background: Current data regarding the associated factors of prurigo nodularis are still uncertain, except for atopic predisposition. Objectives: The purposes of this study were to (1) determine the frequencies of xerosis and other accompanying diseases of female patients with prurigo nodularis; (2) compare the demographic, clinical and accompanying disease characteristics by grouping these patients according to whether they have associated xerosis (who were subsequently subgrouped as atopic or non-atopic) or not. Methods: In this retrospective descriptive study, 80 females with PN were categorized according to the accompanying diseases (dermatological, systemic, neurological, psychogenic, mixed, or undetermined origin). Results: A total of 45 associated co-factors including dermatological in 63 (78.8%), systemic in 57 (71.3%), psychological in 33 (41.3%) and neurological co-factors in 14 (17.5%) of all patients with prurigo nodularis were detected. Xerosis was observed in 48 (60%) patients (non-atopic co-factors in 66.7% of them). The ratio of patients with mixed co-factors, dermatological+systemic co-factors and dermatological+systemic+psychological co-factors were found to be significantly higher in patients with xerosis compared to those without xerosis. Study limitations: Our study has certain limitations such as the absence of an age-matched control group, absence of follow-up data and the fact that the diagnosis of xerosis has not been based on objective methods. Conclusions: Xerosis has been identified in more than half of the patients with PN and it has been determined that in most patients xerosis is associated especially with diabetes mellitus and other conditions related to prurigo nodularis.

Published
2018

18. Contact sensitization to cosmetic series of allergens in patients with rosacea: A prospective controlled study.

Author

Ozbagcivan, Ozlem, Akarsu, Sevgi, Dolas, Necla, and Fetil, Emel

Subjects
*ALLERGENS, *CONTACT dermatitis, *LONGITUDINAL method, *ALLERGIES, *BETAINE
Abstract

Background: Previous studies have documented the cosmetic allergic contact dermatitis due to common cosmetic allergens in standard series and various cosmetic products used in rosacea patients; however, the prevalence of contact sensitization to other cosmetic allergens other than those in standard series is largely unknown. Aims: To assess the prevalence of contact sensitization to a European cosmetic series of allergens (Chemotechnique Diagnostics AB, Malmö, Sweden) in rosacea patients and to compare this with the prevalence observed in general population. Methods: In this prospective monocenter study, 103 patients with rosacea and 104 control subjects were investigated for contact sensitizations via patch testing the cosmetic series including 49 allergens. Results: At least one positive allergic reaction was observed in 62 (60.2%) rosacea patients, and in 25 (24.0%) control subjects. Compared with control subjects, rosacea patients were statistically more likely to have positive patch tests. The most common allergens giving positive results were octyl gallate (10.68%), dodecyl gallate (8.74%), tert‐Butylhydroquinone (7.77%), thimerosal (6.80%), euxyl K400 (6.80%), cocamidopropyl betaine (5.83%), and 2,6‐Di‐tert‐butyl‐4‐cresol (4.85%). Conclusions: This study shows that rosacea patients show a strikingly high prevalence of contact sensitization to cosmetic allergens. We recommend the additional use of cosmetic series for patch testing, and the careful use of cosmetics in rosacea patients if cosmetic contact sensitivity is suspected. [ABSTRACT FROM AUTHOR]

Published
2020
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