1. Discrete Nanoparticles ofRuta GraveolensInduces the Bacterial and Fungal Biofilm Inhibition
- Author
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Jeyachandran Sivakamavalli, Oyyappan Deepa, and Baskaralingam Vaseeharan
- Subjects
Staphylococcus aureus ,Antifungal Agents ,Ruta graveolens ,Clinical Biochemistry ,Nanoparticle ,Silver nanoparticle ,Microbiology ,Disk Diffusion Antimicrobial Tests ,Candida albicans ,Fourier transform infrared spectroscopy ,Ruta ,biology ,Plant Extracts ,Chemistry ,Biofilm ,Cell Biology ,General Medicine ,biology.organism_classification ,Anti-Bacterial Agents ,Plant Leaves ,Phytochemical ,Biofilms ,Pseudomonas aeruginosa ,Nanoparticles ,Antibacterial activity ,Nuclear chemistry - Abstract
Ruta graveolens silver nanoparticles (AgNPs) showed the color change within 30 min and characterized using UV–visible spectra, Fourier Transform Infrared (FTIR), X-ray Diffraction (XRD) and Transmission Electron Microscopy (TEM). UV–visible spectrum of R. graveolens AgNPs showed the sharp peak at the wavelength of 440–560 nm. XRD patterns confirmed that crystalline nature of R. graveolens AgNPs and FTIR results revealed that phytochemical reaction of these R. graveolens is responsible for the synthesis of AgNPs. TEM results showed the size of the R. graveolens AgNPs around 30–50 nm with spherical and triangular nature. Further, the antibacterial and antibiofilm activity of R. graveolens AgNPs showed the effective inhibitory activity against clinically important Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. Our findings suggest that R. graveolens AgNPs can be exploited toward the development of potential antibacterial agents for various biomedical and environmental applications.
- Published
- 2014
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