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15 results on '"Oyon, Daniel E."'

2. Predictors of salvage therapy for parasagittal meningiomas treated with primary surgery, radiosurgery, or surgery plus adjuvant radiotherapy

Author

Joy Trybula, S., Nandoliya, Khizar R., Youngblood, Mark W., Karras, Constantine L., Fernandez, Luis G., Oyon, Daniel E., Texakalidis, Pavlos, Khan, Osaama H., Lesniak, Maciej S., Tate, Matthew C., Rosenow, Joshua M., Hill, Virginia B., Hijaz, Tarek A., Russell, Eric J., Sachdev, Sean, Kalapurakal, John A., Horbinski, Craig M., Magill, Stephen T., and Chandler, James P.

Published
2024
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4. Immunomonitoring in glioma immunotherapy: current status and future perspectives.

Author

Lamano, Jonathan B, Ampie, Leonel, Choy, Winward, Kesavabhotla, Kartik, DiDomenico, Joseph D, Oyon, Daniel E, Parsa, Andrew T, and Bloch, Orin

Subjects
T-Lymphocytes, Cytotoxic, Animals, Humans, Glioma, Brain Neoplasms, Immunotherapy, Glioblastoma, Immunomonitoring, Vaccine, Brain Disorders, Vaccine Related, Brain Cancer, Rare Diseases, Cancer, Neurosciences, Immunization, Clinical Research, Clinical Trials and Supportive Activities, Detection, screening and diagnosis, 4.1 Discovery and preclinical testing of markers and technologies, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract

Given the continued poor clinical outcomes and refractory nature of glioblastoma multiforme to traditional interventions, immunotherapy is gaining traction due to its potential for specific tumor-targeting and long-term antitumor protective surveillance. Currently, development of glioma immunotherapy relies on overall survival as an endpoint in clinical trials. However, the identification of surrogate immunologic biomarkers can accelerate the development of successful immunotherapeutic strategies. Immunomonitoring techniques possess the potential to elucidate immunological mechanisms of antitumor responses, monitor disease progression, evaluate therapeutic effect, identify candidates for immunotherapy, and serve as prognostic markers of clinical outcome. Current immunomonitoring assays assess delayed-type hypersensitivity, T cell proliferation, cytotoxic T-lymphocyte function, cytokine secretion profiles, antibody titers, and lymphocyte phenotypes. Yet, no single immunomonitoring technique can reliably predict outcomes, relegating immunological markers to exploratory endpoints. In response, the most recent immunomonitoring assays are incorporating emerging technologies and novel analysis techniques to approach the goal of identifying a competent immunological biomarker which predicts therapy responsiveness and clinical outcome. This review addresses the current status of immunomonitoring in glioma vaccine clinical trials with emphasis on correlations with clinical response.

Published
2016

6. Supplementary Tables from Glioblastoma-Derived IL6 Induces Immunosuppressive Peripheral Myeloid Cell PD-L1 and Promotes Tumor Growth

Author

Lamano, Jonathan B., primary, Lamano, Jason Balquidera, primary, Li, Yuping D., primary, DiDomenico, Joseph D., primary, Choy, Winward, primary, Veliceasa, Dorina, primary, Oyon, Daniel E., primary, Fakurnejad, Shayan, primary, Ampie, Leonel, primary, Kesavabhotla, Kartik, primary, Kaur, Rajwant, primary, Kaur, Gurvinder, primary, Biyashev, Dauren, primary, Unruh, Dusten J., primary, Horbinski, Craig M., primary, James, C. David, primary, Parsa, Andrew T., primary, and Bloch, Orin, primary

Published
2023
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7. Supplementary Methods from Glioblastoma-Derived IL6 Induces Immunosuppressive Peripheral Myeloid Cell PD-L1 and Promotes Tumor Growth

Author

Lamano, Jonathan B., primary, Lamano, Jason Balquidera, primary, Li, Yuping D., primary, DiDomenico, Joseph D., primary, Choy, Winward, primary, Veliceasa, Dorina, primary, Oyon, Daniel E., primary, Fakurnejad, Shayan, primary, Ampie, Leonel, primary, Kesavabhotla, Kartik, primary, Kaur, Rajwant, primary, Kaur, Gurvinder, primary, Biyashev, Dauren, primary, Unruh, Dusten J., primary, Horbinski, Craig M., primary, James, C. David, primary, Parsa, Andrew T., primary, and Bloch, Orin, primary

Published
2023
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8. Supplementary Data from Glioblastoma-Derived IL6 Induces Immunosuppressive Peripheral Myeloid Cell PD-L1 and Promotes Tumor Growth

Author

Lamano, Jonathan B., primary, Lamano, Jason Balquidera, primary, Li, Yuping D., primary, DiDomenico, Joseph D., primary, Choy, Winward, primary, Veliceasa, Dorina, primary, Oyon, Daniel E., primary, Fakurnejad, Shayan, primary, Ampie, Leonel, primary, Kesavabhotla, Kartik, primary, Kaur, Rajwant, primary, Kaur, Gurvinder, primary, Biyashev, Dauren, primary, Unruh, Dusten J., primary, Horbinski, Craig M., primary, James, C. David, primary, Parsa, Andrew T., primary, and Bloch, Orin, primary

Published
2023
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9. International Tuberculum Sellae Meningioma Study: Preoperative Grading Scale to Predict Outcomes and Propensity-Matched Outcomes by Endonasal Versus Transcranial Approach

Author

Magill, Stephen T., Schwartz, Theodore H., Couldwell, William T., Gardner, Paul A., Heilman, Carl B., Sen, Chandranath, Akagami, Ryojo, Cappabianca, Paolo, Prevedello, Daniel M., McDermott, Michael W., Przybylowski, Colin J., Almefty, Kaith K., Patel, Akash J., Khan, A. Basit, Wu, Kyle C., Bi, Wenya Linda, Dunn, Ian F., Mamelak, Adam N., Ehsan, Mohammad U., Bruce, Jeffrey N., Englander, Zachary K., Wang, Linda M., Youngerman, Brett, Anand, Vijay K., Kacker, Ashutosh, Tabaee, Abtin, Clarke, David B., Walling, Simon A., Hebb, Andrea L. O., Macki, Mohamed, Anand, Sharath K., Rock, Jack P., Baskin, David S., Yewah Gwei, Larisse K., Guthikonda, Bharat, Kosty, Jennifer, Nanda, Anil, Sun, Hai, Culicchia, Frank, Morrow, Kevin, Fannin, Erin, Germanwala, Anand V., Prabhu, Vikram C., Patel, Chirag R., Chaichana, Kaisorn, Quinones-Hinojosa, Alfredo, ReFaey, Karim, Chandler, James P., Fernandez, Luis G., Oyon, Daniel E., Youngblood, Mark W., Golfinos, John G., Placantonakis, Dimitris G., Pacione, Donato, Delavari, Nader, Albonette-Felicio, Thiago, Otto, Bradley A., Carrau, Ricardo L., Han, Seunggu J., Shahin, Maryam N., Brahimaj, Bledi C., Beer-Furlan, André, Byrne, Richard W., Munich, Stephan A., Munoz, Lorenzo F., Liu, James K., Zhao, Kevin, Agarwalla, Pankaj K., Hsueh, Wayne D., Eloy, Jean Anderson, Chang, Steven D., Meola, Antonio, Teng, Hao, Goulart, Carlos R., Rai, Shawn S., Chin, Lawrence S., Ahye, Nicholas, Weaver, Michael, Mangham, William M., Michael, L. Madison, Robertson, Jon H., Dowd, Richard S., Amenta, Peter S., Scullen, Tyler A., de Divitiis, Oreste, Solari, Domenico, Cavallo, Luigi M., Makarenko, Serge, Rizzuto, Michael, Prakash, Swetha, Chen, William C., El-Sayed, Ivan H., Nguyen, Minh P., Morshed, Ramin A., Theodosopoulos, Philip V., Aghi, Manish K., Santarius, Thomas, Stastna, Daniela, Williams, Brian J., Andaluz, Norberto, Adappa, Nithin D., Palmer, James N., Grady, M. Sean, Lee, John Y. K., Buch, Love, Sharma, Nikhil, Joshi, Disha, Champagne, Pierre-Olivier, Valappil, Benita, Kumar, Jay I., Agarwalla, Pankaj K., Agazzi, Siviero, van Loveren, Harry, Zada, Gabriel, Strickland, Benjamin, Garrett, Norman E., Plitt, Aaron R., Barnett, Samuel L., Mickey, Bruce E., Garzon-Muvdi, Tomas, Nassiri, Farshad, Gentili, Fred, Kalyvas, Aristotelis, Zadeh, Gelareh, Karsy, Michael, Sayyahmelli, Sima, Baskaya, Mustafa K., Morone, Peter J., Cavallo, Claudio, Sylvester, Peter T., and Chicoine, Michael R.

Published
2023
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10. International Tuberculum Sellae Meningioma Study: Surgical Outcomes and Management Trends

Author

Magill, Stephen T., Schwartz, Theodore H., Couldwell, William T., Gardner, Paul A., Heilman, Carl B., Sen, Chandranath, Akagami, Ryojo, Cappabianca, Paolo, Prevedello, Daniel M., McDermott, Michael W., Przybylowski, Colin J., Almefty, Kaith K., Patel, Akash J., Khan, A. Basit, Wu, Kyle C., Bi, Wenya Linda, Dunn, Ian F., Mamelak, Adam N., Ehsan, Mohammad U., Bruce, Jeffrey N., Englander, Zachary K., Wang, Linda M., Youngerman, Brett, Anand, Vijay K., Kacker, Ashutosh, Tabaee, Abtin, Clarke, David B., Walling, Simon A., Hebb, Andrea L. O., Macki, Mohamed, Anand, Sharath K., Rock, Jack P., Baskin, David S., Yewah Gwei, Larisse K., Guthikonda, Bharat, Kosty, Jennifer, Nanda, Anil, Sun, Hai, Culicchia, Frank, Morrow, Kevin, Fannin, Erin, Germanwala, Anand V., Prabhu, Vikram C., Patel, Chirag R., Chaichana, Kaisorn, Quinones-Hinojosa, Alfredo, ReFaey, Karim, Chandler, James P., Fernandez, Luis G., Oyon, Daniel E., Youngblood, Mark W., Golfinos, John G., Placantonakis, Dimitris G., Pacione, Donato, Delavari, Nader, Albonette-Felicio, Thiago, Otto, Bradley A., Carrau, Ricardo L., Han, Seunggu J., Shahin, Maryam N., Brahimaj, Bledi C., Beer-Furlan, André, Byrne, Richard W., Munich, Stephan A., Munoz, Lorenzo F., Liu, James K., Zhao, Kevin, Agarwalla, Pankaj K., Hsueh, Wayne D., Eloy, Jean Anderson, Chang, Steven D., Meola, Antonio, Teng, Hao, Goulart, Carlos R., Rai, Shawn S., Chin, Lawrence S., Ahye, Nicholas, Weaver, Michael, Mangham, William M., Michael, L. Madison, Robertson, Jon H., Dowd, Richard S., Amenta, Peter S., Scullen, Tyler A., de Divitiis, Oreste, Solari, Domenico, Cavallo, Luigi M., Makarenko, Serge, Rizzuto, Michael, Prakash, Swetha, Chen, William C., El-Sayed, Ivan H., Nguyen, Minh P., Morshed, Ramin A., Theodosopoulos, Philip V., Aghi, Manish K., Santarius, Thomas, Stastna, Daniela, Williams, Brian J., Andaluz, Norberto, Adappa, Nithin D., Palmer, James N., Grady, M. Sean, Lee, John Y. K., Buch, Love, Sharma, Nikhil, Joshi, Disha, Champagne, Pierre-Olivier, Valappil, Benita, Kumar, Jay I., Agarwalla, Pankaj K., Agazzi, Siviero, van Loveren, Harry, Zada, Gabriel, Strickland, Benjamin, Garrett, Norman E., Plitt, Aaron R., Barnett, Samuel L., Mickey, Bruce E., Garzon-Muvdi, Tomas, Nassiri, Farshad, Gentili, Fred, Kalyvas, Aristotelis, Zadeh, Gelareh, Neurosurgery, Division of, Hospital, Toronto Western, Toronto, University of, Toronto, Ontario, Karsy, Canada; Michael, Sayyahmelli, Sima, Baskaya, Mustafa K., Morone, Peter J., Cavallo, Claudio, Sylvester, Peter T., and Chicoine, Michael R.

Published
2023
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12. Glioblastoma-Derived IL6 Induces Immunosuppressive Peripheral Myeloid Cell PD-L1 and Promotes Tumor Growth

Author

Lamano, Jonathan B., primary, Lamano, Jason Balquidera, additional, Li, Yuping D., additional, DiDomenico, Joseph D., additional, Choy, Winward, additional, Veliceasa, Dorina, additional, Oyon, Daniel E., additional, Fakurnejad, Shayan, additional, Ampie, Leonel, additional, Kesavabhotla, Kartik, additional, Kaur, Rajwant, additional, Kaur, Gurvinder, additional, Biyashev, Dauren, additional, Unruh, Dusten J., additional, Horbinski, Craig M., additional, James, C. David, additional, Parsa, Andrew T., additional, and Bloch, Orin, additional

Published
2019
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15. An Unusual Case of Gordonia sputiCerebral Infection

Author

Santoiemma, Phillip P., Oyon, Daniel E., Tate, Matthew C., and Bolon, Maureen K.

Abstract

Gordonia sputiis an aerobic, gram-positive, weakly acid fast rod found in soil and water. We present the first known case of G. sputicerebral infection as a consequence of iatrogenic intrathecal chemotherapy through an Ommaya reservoir. The patient was successfully treated with a 14-day course of antibiotics without any further complications. There is sparse information on both infections due to and treatment of G. sputi. We present our case report as well as a review of the literature on the epidemiology, susceptibility, and treatment recommendations for G. sputiinfections.

Published
2021
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