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1. Evaluation of eight lateral flow tests for the detection of anti-SARS-CoV-2 antibodies in a vaccinated population

Author

Greenland-Bews, Caitlin, Byrne, Rachel L., Owen, Sophie I., Watkins, Rachel L., Bengey, Daisy, Buist, Kate, Clerkin, Karina, Escadafal, Camille, Finch, Lorna S., Gould, Susan, Giorgi, Emanuele, Hodgkinson, Andy, Mashenko, Larysa, Powell, Darren, Savage, Helen R., Thompson, Caitlin R., Turtle, Lance, Wardale, Jahanara, Wooding, Dominic, Edwards, Thomas, Atienzar, Ana Cubas, and Adams, Emily R.

Published
2023
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2. Twelve lateral flow immunoassays (LFAs) to detect SARS-CoV-2 antibodies

Author

Owen, Sophie I., Williams, Christopher T., Garrod, Gala, Fraser, Alice J., Menzies, Stefanie, Baldwin, Lisa, Brown, Lottie, Byrne, Rachel L., Collins, Andrea M., Cubas-Atienzar, Ana I., de Vos, Margaretha, Edwards, Thomas, Escadafal, Camille, Ferreira, Daniela M., Fletcher, Tom, Hyder-Wright, Angela, Kay, Grant A., Kontogianni, Konstantina, Mason, Jenifer, Mitsi, Elena, Planche, Tim, Sacks, Jilian A., Taylor, Joseph, Todd, Stacy, Tully, Caroline, Cuevas, Luis E., and Adams, Emily R.

Published
2022
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4. Gauging the skin resident Leishmania parasites through a loop mediated isothermal amplification (LAMP) assay in post-kala-azar dermal leishmaniasis

Author

Ghosh, Prakash, Chowdhury, Rajashree, Maruf, Shomik, Picado, Albert, Hossain, Faria, Owen, Sophie I., Nath, Rupen, Baker, James, Hasnain, Md Golam, Shomik, Mohammad Sohel, Ghosh, Debashis, Rashid, Masud, Rashid, Md. Utba, Sagar, Soumik Kha, Rahat, Md. Abu, Basher, Ariful, Nath, Proggananda, Edwards, Thomas, Andrews, Jason R., Duthie, Malcolm S., de Souza, Dziedzom K., Adams, Emily R., Ndungu, Joseph, Cruz, Israel, and Mondal, Dinesh

Published
2022
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7. Self-sampling of capillary blood for SARS-CoV-2 serology

Author

Brown, Lottie, Byrne, Rachel L., Fraser, Alice, Owen, Sophie I., Cubas-Atienzar, Ana I., Williams, Christopher T., Kay, Grant A., Cuevas, Luis E., Fitchett, Joseph R. A., Fletcher, Tom, Garrod, Gala, Kontogianni, Konstantina, Krishna, Sanjeev, Menzies, Stefanie, Planche, Tim, Sainter, Chris, Staines, Henry M., Turtle, Lance, and Adams, Emily R.

Published
2021
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8. Additional file 1 of Evaluation of eight lateral flow tests for the detection of anti-SARS-CoV-2 antibodies in a vaccinated population

Author

Greenland-Bews, Caitlin, Byrne, Rachel L., Owen, Sophie I., Watkins, Rachel L., Bengey, Daisy, Buist, Kate, Clerkin, Karina, Escadafal, Camille, Finch, Lorna S., Gould, Susan, Giorgi, Emanuele, Hodgkinson, Andy, Mashenko, Larysa, Powell, Darren, Savage, Helen R., Thompson, Caitlin R., Turtle, Lance, Wardale, Jahanara, Wooding, Dominic, Edwards, Thomas, Atienzar, Ana Cubas, and Adams, Emily R.

Abstract

Additional file 1. Supplementary Materials.

Published
2023
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11. Evaluation of Eight Lateral Flow Tests For The Detection Of Anti-SARS-CoV-2 Antibodies In A Vaccinated Population

Author

Greenland-Bews, Caitlin, primary, Byrne, Rachel L, additional, Owen, Sophie I, additional, Watkins, Rachel L, additional, Bengey, Daisy, additional, Buist, Kate, additional, Clerkin, Karina, additional, Escadafal, Camille, additional, Finch, Lorna S, additional, Gould, Susan, additional, Giorgi, Emanuele, additional, Hodgkinson, Andrew, additional, Mashenko, Larysa, additional, Powell, Darren, additional, Savage, Helen R, additional, Thompson, Caitlin R, additional, Turtle, Lance, additional, Wardale, Jahanara, additional, Wooding, Dominic, additional, Edwards, Thomas, additional, Cubas Atienzar, Ana I, additional, and Adams, Emily R, additional

Published
2022
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12. Saliva Alternative to Upper Respiratory Swabs for SARS-CoV-2 Diagnosis

Author

Byrne, Rachel L., Kay, Grant A., Kontogianni, Konstantina, Aljayyoussi, Ghaith, Brown, Lottie, Collins, Andrea M., Cuevas, Luis E., Ferreira, Daniela M., Fletcher, Tom, Fraser, Alice J., Garrod, Gala, Hill, Helen, Hughes, Grant L., Menzies, Stefanie, Mitsi, Elena, Owen, Sophie I., Patterson, Edward I., Todd, Stacy, Williams, Christopher T., Hyder-Wright, Angela, Adams, Emily R., and Cubas-Atienzar, Ana I.

Subjects
Polymerase chain reaction -- Usage, COVID-19 -- Diagnosis, Salivary diagnostics -- Methods, Health
Abstract

Quantitative reverse transcription PCR (qRTPCR) is the diagnostic standard for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease (COVID-19) (1). Testing usually is conducted on [...]

Published
2020
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13. Evaluation of Loopamp™ Leishmania Detection Kit and Leishmania Antigen ELISA for Post-Elimination Detection and Management of Visceral Leishmaniasis in Bangladesh

Author

Hossain, Faria, Picado, Albert, Owen, Sophie I., Ghosh, Prakash, Chowdhury, Rajashree, Maruf, Shomik, Khan, Md. Anik Ashfaq, Rashid, Md. Utba, Nath, Rupen, Baker, James, Ghosh, Debashis, Adams, Emily R., Duthie, Malcolm S., Hossain, Md. Sakhawat, Basher, Ariful, Nath, Proggananda, Aktar, Fatima, Cruz, Israel, Mondal, Dinesh, Hossain, Faria, Picado, Albert, Owen, Sophie I., Ghosh, Prakash, Chowdhury, Rajashree, Maruf, Shomik, Khan, Md. Anik Ashfaq, Rashid, Md. Utba, Nath, Rupen, Baker, James, Ghosh, Debashis, Adams, Emily R., Duthie, Malcolm S., Hossain, Md. Sakhawat, Basher, Ariful, Nath, Proggananda, Aktar, Fatima, Cruz, Israel, and Mondal, Dinesh

Abstract

With reduced prevalence of visceral leishmaniasis (VL) in the Indian subcontinent (ISC), direct and field deployable diagnostic tests are needed to implement an effective diagnostic and surveillance algorithm for post-elimination VL control. In this regard, here we investigated the diagnostic efficacies of a loop-mediated isothermal amplification (LAMP) assay (Loopamp™ Leishmania Detection Kit, Eiken Chemical CO., Ltd, Japan), a real-time quantitative PCR assay (qPCR) and the Leishmania antigen ELISA (CLIN-TECH, UK) with different sampling techniques and evaluated their prospect to incorporate into post-elimination VL control strategies. Eighty clinically and rK39 rapid diagnostic test confirmed VL cases and 80 endemic healthy controls were enrolled in the study. Peripheral blood and dried blood spots (DBS) were collected from all the participants at the time of diagnosis. DNA was extracted from whole blood (WB) and DBS via silica columns (QIAGEN) and boil & spin (B&S) methods and tested with qPCR and Loopamp. Urine was collected from all participants at the time of diagnosis and was directly subjected to the Leishmania antigen ELISA. 41 patients were followed up and urine samples were collected at day 30 and day 180 after treatment and ELISA was performed. The sensitivities of the Loopamp-WB(B&S) and Loopamp-WB(QIA) were 96.2% (95% CI 89·43-99·22) and 95% (95% CI 87·69-98·62) respectively. The sensitivity of Loopamp- DBS(QIA) was 85% (95% CI 75·26- 92·00). The sensitivities of the qPCR-WB(QIA) and qPCR-DBS(QIA) were 93.8% (95% CI 86·01-97·94) and 72.5% (95% CI 61·38-81·90) respectively. The specificity of all molecular assays was 100%. The sensitivity and specificity of the Leishmania antigen ELISA were 97.5% (95% CI 91·47-99·70) and 91.95% (95% CI 84·12-96·70) respectively. The Leishmania antigen ELISA depicted clinical cure at day 180 in all the followed-up cases. Efficacy and sustainability identify the Loopamp-WB(B&S) and the Leishmania antigen ELISA as promisi

Published
2021

14. Accuracy of the Mologic COVID-19 rapid antigen test: a prospective multi-centre analytical and clinical evaluation

Author

Cubas-Atienzar, Ana I, primary, Bell, Fiona, additional, Byrne, Rachel L., additional, Buist, Kate, additional, Clark, David J., additional, Cocozza, Michael, additional, Collins, Andrea M., additional, Cuevas, Luis E., additional, Duvoix, Annelyse, additional, Easom, Nicholas, additional, Edwards, Thomas, additional, Ferreira, Daniella M., additional, Fletcher, Tom, additional, Groppelli, Elisabetta, additional, Hyder-Wright, Angela, additional, Kadamus, Ewelina, additional, Kirwan, Daniela E., additional, Kontogianni, Konstantina, additional, Krishna, Sanjeev, additional, Kluczna, Diana, additional, Mark, Julian, additional, Mensah-Kane, Josephine, additional, Miller, Elisha, additional, Mitsi, Elena, additional, Norton, Donna, additional, O'Connor, Emma, additional, Owen, Sophie I., additional, Planche, Tim, additional, Shelley, Samuel, additional, Staines, Henry M., additional, Tate, David, additional, Thompson, Caitlin R., additional, Walker, Gemma, additional, Williams, Christopher T., additional, Wooding, Dominic, additional, Fitchett, Joseph R. A., additional, and Adams, Emily R., additional

Published
2021
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15. Evaluation of Loopamp™ Leishmania Detection Kit and Leishmania Antigen ELISA for Post-Elimination Detection and Management of Visceral Leishmaniasis in Bangladesh

Author

Hossain, Faria, primary, Picado, Albert, additional, Owen, Sophie I., additional, Ghosh, Prakash, additional, Chowdhury, Rajashree, additional, Maruf, Shomik, additional, Khan, Md. Anik Ashfaq, additional, Rashid, Md. Utba, additional, Nath, Rupen, additional, Baker, James, additional, Ghosh, Debashis, additional, Adams, Emily R., additional, Duthie, Malcolm S., additional, Hossain, Md. Sakhawat, additional, Basher, Ariful, additional, Nath, Proggananda, additional, Aktar, Fatima, additional, Cruz, Israel, additional, and Mondal, Dinesh, additional

Published
2021
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16. Immunoglobulin-G Enzyme-Linked Immunosorbent Assay Predicts Neutralising Antibody Response in Convalescent SARS-CoV-2 Patients

Author

Kay, Grant A, primary, Owen, Sophie I, additional, Giorgi, Emanuele, additional, Williams, Christopher T, additional, Menzies, Stefanie, additional, Clark, David J, additional, Cuevas, Luis, additional, Davies, Benedict M O, additional, Eckersley, Nicholas M, additional, Hughes, Grant L, additional, Kirwan, Daniela E, additional, Krishna, Sanjeev, additional, Patterson, Edward I, additional, Planche, Tim, additional, Staines, Henry M, additional, and Adams, Emily R, additional

Published
2021
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17. Evaluation of qPCR on blood and skin microbiopsies, peripheral blood buffy coat smear, and urine antigen ELISA for diagnosis and test of cure for visceral leishmaniasis in HIV-coinfected patients in India: a prospective cohort study

Author

Owen, Sophie I, primary, Burza, Sakib, additional, Kumar, Shiril, additional, Verma, Neena, additional, Mahajan, Raman, additional, Harshana, Amit, additional, Pandey, Krishna, additional, Cloots, Kristien, additional, Adams, Emily, additional, and Das, Pradeep, additional

Published
2021
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18. SARS-CoV-2 Transmission Risk from sports Equipment (STRIKE)

Author

Edwards, Thomas, primary, Kay, Grant A, additional, Aljayyoussi, Ghaith, additional, Owen, Sophie I, additional, Harland, Andy R, additional, Pierce, Nicholas S, additional, Calder, James D F, additional, Fletcher, Tom E, additional, and Adams, Emily R, additional

Published
2021
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19. IgG Seroconversion and Pathophysiology in Severe Acute Respiratory Syndrome Coronavirus 2 Infection

Author

Staines, Henry M., primary, Kirwan, Daniela E., additional, Clark, David J., additional, Adams, Emily R., additional, Augustin, Yolanda, additional, Byrne, Rachel L., additional, Cocozza, Michael, additional, Cubas-Atienzar, Ana I., additional, Cuevas, Luis E., additional, Cusinato, Martina, additional, Davies, Benedict M.O., additional, Davis, Mark, additional, Davis, Paul, additional, Duvoix, Annelyse, additional, Eckersley, Nicholas M., additional, Forton, Daniel, additional, Fraser, Alice J., additional, Garrod, Gala, additional, Hadcocks, Linda, additional, Hu, Qinxue, additional, Johnson, Michael, additional, Kay, Grant A., additional, Klekotko, Kesja, additional, Lewis, Zawditu, additional, Macallan, Derek C., additional, Mensah-Kane, Josephine, additional, Menzies, Stefanie, additional, Monahan, Irene, additional, Moore, Catherine M., additional, Nebe-von-Caron, Gerhard, additional, Owen, Sophie I., additional, Sainter, Chris, additional, Sall, Amadou A., additional, Schouten, James, additional, Williams, Christopher T., additional, Wilkins, John, additional, Woolston, Kevin, additional, Fitchett, Joseph R.A., additional, Krishna, Sanjeev, additional, and Planche, Tim, additional

Published
2021
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20. Self-sampling of capillary blood for serological testing of SARS-CoV-2 by COVID-19 IgG ELISA

Author

Brown, Lottie, primary, Byrne, Rachel L, additional, Fraser, Alice, additional, Owen, Sophie I, additional, Cubas-Atienzar, Ana I, additional, Williams, Chris, additional, Kay, Grant A, additional, Cuevas, Luis E, additional, Fitchett, Joseph R A, additional, Fletcher, Tom, additional, Garrod, Gala, additional, Kontogianni, Konstantina, additional, Krishna, Sanjeev, additional, Menzies, Stefanie, additional, Planche, Tim, additional, Sainter, Chris, additional, Staines, Henry M, additional, Turtle, Lance, additional, and Adams, Emily R, additional

Published
2020
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21. Saliva offers a sensitive, specific and non-invasive alternative to upper respiratory swabs for SARS-CoV-2 diagnosis

Author

Byrne, Rachel L, primary, Kay, Grant A, additional, Kontogianni, Konstantina, additional, Brown, Lottie, additional, Collins, Andrea M, additional, Cuevas, Luis E., additional, Ferreira, Daniela M, additional, Fraser, Alice J, additional, Garrod, Gala, additional, Hill, Helen, additional, Menzies, Stefanie, additional, Mitsi, Elena, additional, Owen, Sophie I, additional, Williams, Christopher T, additional, Hyder-Wright, Angela, additional, Adams, Emily R, additional, and Cubas-Atienzar, Ana I, additional

Published
2020
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22. Dynamics of IgG seroconversion and pathophysiology of COVID-19 infections

Author

Staines, Henry M, primary, Kirwan, Daniela E, additional, Clark, David J, additional, Adams, Emily R, additional, Augustin, Yolanda, additional, Byrne, Rachel L, additional, Cocozza, Michael, additional, Cubas-Atienzar, Ana I, additional, Cuevas, Luis E., additional, Cusinato, Martina, additional, Davies, Benedict M O, additional, Davis, Mark, additional, Davis, Paul, additional, Duvoix, Annelyse, additional, Eckersley, Nicholas M, additional, Forton, Daniel, additional, Fraser, Alice J, additional, Garrod, Gala, additional, Hadcocks, Linda, additional, Hu, Qinxue, additional, Johnson, Michael, additional, Kay, Grant A, additional, Klekotko, Kesja, additional, Lewis, Zawditu, additional, Macallan, Derek C, additional, Mensah-Kane, Josephine, additional, Menzies, Stefanie, additional, Monahan, Irene, additional, Moore, Catherine M, additional, Nebe-von-Caron, Gerhard, additional, Owen, Sophie I, additional, Sainter, Chris, additional, Sall, Amadou A, additional, Schouten, James, additional, Williams, Chris, additional, Wilkins, John, additional, Woolston, Kevin, additional, Fitchett, Joseph R A, additional, Krishna, Sanjeev, additional, and Planche, Tim, additional

Published
2020
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23. Rapid development of COVID-19 rapid diagnostics for low resource settings: accelerating delivery through transparency, responsiveness, and open collaboration

Author

Adams, Emily R, primary, Augustin, Yolanda, additional, Byrne, Rachel L, additional, Clark, David J, additional, Cocozza, Michael, additional, Cubas-Atienzar, Ana I, additional, Cuevas, Luis E., additional, Cusinato, Martina, additional, Davies, Benedict M O, additional, Davis, Mark, additional, Davis, Paul, additional, Duvoix, Annelyse, additional, Eckersley, Nicholas M, additional, Edwards, Thomas, additional, Fletcher, Tom, additional, Fraser, Alice J, additional, Garrod, Gala, additional, Hadcocks, Linda, additional, Hu, Qinxue, additional, Johnson, Michael, additional, Kay, Grant A, additional, Keymer, Katherine, additional, Kirwan, Daniela, additional, Klekotko, Kesja, additional, Lewis, Zawditu, additional, Mason, Jenifer, additional, Mensah-Kane, Josie, additional, Menzies, Stefanie, additional, Monahan, Irene, additional, Moore, Catherine M, additional, Nebe-von-Caron, Gerhard, additional, Owen, Sophie I, additional, Planche, Tim, additional, Sainter, Chris, additional, Schouten, James, additional, Staines, Henry M, additional, Turtle, Lance, additional, Williams, Chris, additional, Wilkins, John, additional, Woolston, Kevin, additional, Sall, Amadou Alpha, additional, Fitchett, Joseph R A, additional, and Krishna, Sanjeev, additional

Published
2020
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