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8. The impact of time to death in donors after circulatory death on recipient outcome in simultaneous pancreas-kidney transplantation

Author

Malik, Abdullah K., Tingle, Samuel J., Chung, Nicholas, Owen, Ruth, Mahendran, Balaji, Counter, Claire, Sinha, Sanjay, Muthasamy, Anand, Sutherland, Andrew, Casey, John, Drage, Martin, van Dellen, David, Callaghan, Chris J., Elker, Doruk, Manas, Derek M., Pettigrew, Gavin J., Wilson, Colin H., and White, Steven A.

Published
2024
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9. Assessment of left ventricular tissue mitochondrial bioenergetics in patients with stable coronary artery disease

Author

Jones, Richard E., Gruszczyk, Anja V., Schmidt, Christina, Hammersley, Daniel J., Mach, Lukas, Lee, Michael, Wong, Joyce, Yang, Ming, Hatipoglu, Suzan, Lota, Amrit S., Barnett, Sam N., Toscano-Rivalta, Rebecca, Owen, Ruth, Raja, Shahzad, De Robertis, Fabio, Smail, Hassiba, De-Souza, Anthony, Stock, Ulrich, Kellman, Peter, Griffin, Julian, Dumas, Marc-Emmanuel, Martin, Jack L., Saeb-Parsy, Kourosh, Vazir, Ali, Cleland, John G. F., Pennell, Dudley J., Bhudia, Sunil K., Halliday, Brian P., Noseda, Michela, Frezza, Christian, Murphy, Michael P., and Prasad, Sanjay K.

Published
2023
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12. Sex Differences in the Clinical Presentation and Natural History of Dilated Cardiomyopathy

Author

Owen, Ruth, Buchan, Rachel, Frenneaux, Michael, Jarman, Julian W.E., Baruah, Resham, Lota, Amrit S., Halliday, Brian P., Roberts, Angharad M., Izgi, Cemil, Van Spall, Harriette G.C., Michos, Erin D., McMurray, John J.V., Januzzi, James L., Pennell, Dudley J., Cook, Stuart A., Ware, James S., Barton, Paul J., Gregson, John, Prasad, Sanjay K., and Tayal, Upasana

Published
2024
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13. Biolimus-eluting vs. other limus-eluting stents in NSTE-ACS: A pooled analysis of GLASSY and TWILIGHT

Author

Spirito, Alessandro, Valgimigli, Marco, Cao, Davide, Baber, Usman, Mehta, Shamir R., Gibson, C. Michael, Steg, Gabriel P., Sharma, Samin K., Goel, Ridhima, Huber, Kurt, Kunadian, Vijay, Escaned, Javier, Franzone, Anna, Yaling, Han, Collier, Timothy, Kaul, Upendra, Kornowski, Ran, Krucoff, Mitchell, Moliterno, David, Sartori, Samantha, Owen, Ruth, Zhang, Zhongjie, Dangas, George D., Kastrati, Adnan, Angiolillo, Dominick J., Cohen, David J., Vranckx, Pascal, Windecker, Stephan, Pocock, Stuart, and Mehran, Roxana

Published
2023
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14. Comprehensive Phenotypic Characterization of Late Gadolinium Enhancement Predicts Sudden Cardiac Death in Coronary Artery Disease

Author

Jones, Richard E., Zaidi, Hassan A., Hammersley, Daniel J., Hatipoglu, Suzan, Owen, Ruth, Balaban, Gabriel, de Marvao, Antonio, Simard, François, Lota, Amrit S., Mahon, Ciara, Almogheer, Batool, Mach, Lukas, Musella, Francesca, Chen, Xiuyu, Gregson, John, Lazzari, Laura, Ravendren, Andrew, Leyva, Francisco, Zhao, Shihua, Vazir, Ali, Lamata, Pablo, Halliday, Brian P., Pennell, Dudley J., Bishop, Martin J., and Prasad, Sanjay K.

Published
2023
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15. Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study

Author

Islam, Madiha, Croft, Nick, Cipriano, Bessie, Francia, Caroline, Khalid, Nosheen, Kingston, Ashley, Lee, Irish, Lehmann, Anouk, Naik, Kinnari, Samuels, Kevin, Plaatjies, Nicolene, Khatun, Hafiza, Bokth, Farjana, Pabriaga, Elise, Saich, Rebecca, Cousins, Hayley, Fraser, Wendy, Thomas, Rachel, Brown, Matthew, White, Benjamin, Kirkineziadis, Nikolaos, Tilley, Bernadette, Porter, Pennie, Bryant, Rachel, Robaczewska, Natalia, Muhammed, Rafeeq, Bi, Rehana, Cotter, Catherine, Grove, Jayne, Hong, Kate, Howman, Ruth, Mitchell, Monica, Clayton, Sophie, Rogers, Louise, Sultan, Sugrah, Rooney, Melanie, Cottrill, Charlotte, Singh, Salil, Dawe, Chris, Hull, Robert, Silva, Natalie, Chadwick, Julie, Robertson, Laura, Manning, Jonathan, Finlayson, Lauren, Roebuck, Allison, Dawson, Joy, Sonwalkar, Sunil, Chambers, Naomi, Robinson, Matthew, Haigh, Andrew, Matapure, Lear, Raine, Tim, George, Varun, Kapizioni, Christina, Strongili, Konstantina, Thompson, Tina, Ahmed, Mohamed, Kontos, Christos, Dawson, Claire, Bourges, Christophe, Barbutti, Isabella, Gozzard, Megan E, Hendy, Philip, Bull, Rhian, Costa, Patricia, Davey, Lisa, Hannington, Hayley, Nundlall, Kribashnie, Martins, Catarina, Avanzi, Laura, Carungcong, Jaime, Barr, Sabrina, Appleby, Richard, Johnson, Emma, Shakweh, Eathar, Phillis, Kath, Gascoyne, Rachel, Crowder, Amanda, Whileman, Amanda, London, Ian, Grounds, Jenny, Martin, Emmeline, Pajak, Susie, Price, Jude, Cawley, Kathryn, Powell, Sandra, Kearsley, Nichola, Dhar, Anjan, Brown, Ellen, Cowton, Amanda, Stamp, Kimberley, Warner, Ben, Stuart, Carmel, Lacey, Louise, de Silva, Shanika, Allcock, Clare, Harvey, Philip, Jones, Lesley, Cooke, Elise, Slater, Jayne, King, Dominic, Brooks, Johanne, Baker, Pearl, Beadle, Hannah, Cruz, Carina, Potter, Debbie, Collum, Joe, Masters, Farzana, Kumar, Aashish, Coetzee, Samantha, Peiu, Mihaela, Icke, Becky, Williams, Jill, Raj, Meena, Gaynor, Edward, Chadokufa, Sibongile, Huggett, Bonita, Meghari, Hamza, El-Khouly, Sara, Kiparissi, Fevronia, Girshab, Waffa, Russell-Walker, Lynda, Jackson, Christopher, Sidler, Sara, Claridge, Andrew, Fowler, Emily, McCafferty, Laura, Haxton, Lesley, Irving, Peter, Christodoulides, Karolina, Clifford, Angela, Dawson, Patrick, Honap, Sailish, Lim, Samuel, Luber, Raphael, Mahiouz, Karina, Meade, Susanna, Raymode, Parizade, Reynolds, Rebecca, Stanton, Anna, Tripoli, Sherill, Hare, Naomi, Odukwe, Sopuluchukwu, Balachandran, Senthuran, North, Emma, North, Jessica, Browne, Bria, Cordle, Jessica, Jameson, Ella, Siaw, Yih Harn, Manzano, Lane, Segal, Jonathan, Al-Bakir, Ibrahim, Khakoo, Imran, Portukhay, Sofiya, Thoua, Nora, Davidson, Katherine, Miah, Jagrul, Canclini, Lisa, Hall, Alex, Furreed, Hassina, Mitchell-Inwang, Christine, Hayes, Melony, Myers, Sally, Talbot, Alison, Turnbull, Jack, Whitehead, Emma, Stamp, Katie, Pattinson, Alison, Mathew, Verghese, Sherris, Leanne, Wilcox, Julie, Ramachandran, Sankaranarayanan, Robertson, Hayley, Harvey, Angela, Hicks, Lucy, Byrne, Tara-Marie, Cabreros, Leilani, Downing-Wood, Hannah, Hunter, Sophie, Saifuddin, Mohammad Aamir, Prabhudev, Hemanth, Balarajah, Sharmili, Krucznski, Jan, Driva, Kalliopi, D'Mello, Andrea, Shah, Parith, Castro-Seoane, Rocio, Ibraheim, Hajir, Constable, Laura E, Lo, Jonathan W, Torkizadeh, Melissa, Hermangild, Sherine K, Sutherland, Helen, Wilhelmsen, Elva, Mackintosh, Katherine, Verma, Ajay M, Sebastian, Juliemol, Peerally, Mohammad Farhad, Guerdette, Anne-marie, Coburn, Susan, Novem lam, Ching Yee, Durrant, Donna, Schaefer, Belinda, Serna, Solange, Shahzad, Muhammad, Kent, Alexandra, Choong, Lee Meng, Pantaloni, Benedetta, Ravdas, Pantelis, Vadamalayan, Babu, Foley, Stephen, Arnold, Becky, Heeley, Cheryl, Lovegrove, Wayne, Sowton, Donna, Allsop, Lynne, Gregory, Heidi, Gill, Mandy, Holmes, Megan, Balan, Valeria, Smith, Susan, Turner, Sarah, Smith, Philip J, Steel, Alan, Bretland, Giovanna, King, Sarah, Lofthouse, Martina, Rigby, Lindsey, Subramanian, Sreedhar, Tyrer, David, Martin, Kate, Probert, Christopher, Kamperidis, Nikolaos, Adedoyin, Temi, Baden, Manisha, Brown, Jeannette, Chacko, Feba, Young, Lisa, Cicchetti, Michela, Saifuddin, Mohammad, Yesupatham, Priya, Gowda, Rohit, Williams, Maureen, Kemp, Karen, Akhand, Rima, Gray, Glaxy, John, Anu, John, Maya, Mohammed, Tasnim, Sathe, Diamond, Jones, Natasha, Soren, Jennifer, Sprakes, Michael, Burton, Julie, Kane, Patricia, Lupton, Stephanie, Bartholomew, Jacqueline, Denis, Elizabeth, Daniels, Alison, MacFaul, George, Scaletta, Diane, Siamia, Loria, Williams, Felicity, Green, Chloe, Ver, Zeljka, Lamb, Chris, Doona, Mary, Hogg, Ashleigh, Jeffrey, Lesley, King, Andrew, Speight, R Alexander, Doyle, Jennifer, Owen, Ruth, Haworth, Jenny, Patterson, Linda, Varnaulasingam, Vithusa, Mowat, Craig, Rice, Debbie, MacFarlane, Susan, MacLeod, Anne, Mohammed, Samera, Murray, Shona, Elliott, Anne, Anne Morris, Mary, Coke, Louise, Hindle, Grace, Kolokouri, Eirini, Wright, Catherine, Lee, Claire, Ward, Nicola, Dann, Adele, Lockett, Melanie, Cranfield, Charlotte, Jennings, Louise, Srivastava, Ankur, Ward, Lana, Jeynes, Nouf, Ranga, Poonam, Rajasekhar, Praveen, Gallagher, Lisa, Ward, Jill, Basnett, Rae, Murphy, Judy, Parking, Lauren, Lawson, Emma, Short, Stacey, Devadason, David, Moran, Gordon, Khan, Neelam, Tarr, Lauren, Olivia, Charmaine, Warbarton, Samantha, Kelly, Sian, Limdi, Jimmy, Goulden, Kay, Javed, Asad, McKenzie, Lauren, Melville, Julie, Liu, Eleanor, Sabine, Joseph, Jacob, Patricia, McSorland, Denise, Schofield, Nick, Cornwall, Lisa, Quirke, James, Crook, Emma, Turner, Anne, Bhandari, Pradeep, Baker-Moffatt, Michelle, Dash, Joanne, Le Poidevin, Alison, Downe, Hayley, Bombeo, Lucille, Blackman, Helen, Smith, Rebecca, Wiles, Alan, Bloxham, Hannah, Dias, Jose, Nadar, Evelyn, Curgenven, Hollie, Gilham, Ellie, Macdonald, Jonathan, Finan, Shona, McMeeken, Faye, Mahmood, Misbah, Shields, Stephanie, Seenan, John Paul, DeSilva, Des, Malkakorpi, Susanna, Carson, Rachel, Lawrence, Holly, Boateng, Ofori, Kpodo, Felix, Whiteoak, Simon, Edger-Earley, Kelli, Vamplew, Luke, Samways, Joanna, Roffe, Sue, Ingram, Sarah, James, Joel, Botfield, Sharon, Hammonds, Fiona, James, Clare, Berry, Zoe, Aspinall, Gemma, Hawkins, Sarah, Parkinson, Marian, Gardner-Thorpe, Helen, Marriott, Suzie, Redstone, Clare, Windak, Halina, Adam, Ana-Marie, Mabb, Hannah, Stevenson, Emma, Record, Jessica, Murray, Charles, Diaba, Cynthia, Joseph, Fexy, Pakou, Glykeria, Gleeson, Yvonne, Nunag, Annalyn, Berrill, James, Stroud, Natalie, Pothecary, Carla, Roche, Lisa, Turner, Keri, Deering, Lisa, Israel, Lynda, Baker, Evelyn, Nash, Maxine, Fagbemi, Andrew, Jennings, Felicia, Mayor, Imelda, Wilson, Jill, Wheeler, Alice, Phillips, Nicola, Gordon, John, Levell, Emma, Zagalo, Silvia, Hoad, Ina, Anil, Bindu, Russell, Richard, Henderson, Paul, Millar, Margaret, Alexakis, Christopher, Michalak, Natalia, Marriott, Cheryl, Stone, Sarah, Pristopan, Veronika, Saunders, John, Burton, Helen, Cambridge, Vanessa, Clark, Tonia, Ekblad, Charlotte, Hierons, Sarah, Katebe, Joyce, Saunsbury, Emma, Perry, Rachel, Brookes, Matthew, Davies, Kathryn, Green, Marie, Plumbe, Ann, Ormerod, Clare, Christensen, Helen, Howlett, Hannah, Keen, Anne, Ogor, Jonathan, Greenhaigh, Marie, Knowles, Karen, Yin, Shanzi, Poulaka, Maria, Anthony, Alpha, Newitt, Emily, Trim, Fiona, Casey, Ruth, Seymour, Katherine, Reed, Catherine, Joy, Lijo, Fogden, Edward, Russell, Kalisha, Hussain, Samia, Phillips, Anne, Abdulla, Muaad, Butterworth, Jeff, Adams, Colene, Carnahan, Mandy, Buckingham, Elizabeth, Childs, Danielle, Magness, Alison, Stickley, Jo, Motherwell, Nichola, Tonks, Louise, Gibson, Hannah, Wistance, Kate, Thomas, Caradog, Brinkworth, Elaine, Connor, Lynda, Cook, Amanda, Rees, Tabitha, Harford, Rachel, Farley, Sean, Jones, Marie, Wesley, Emma, Moss, Alison, Lucas, Jacob, Lorimer, Claire, Oleary, Maria, Dixon, Maxine, Goodchild, Fiona, Twenlow, Rebecca, Pawley, Corinne, Ramadas, Arvind, Tregonning, Julie, Okeke, Olaku, Jackson, Wendy, Koumoutsos, Ioannis, George, Viji, Kunhunny, Swapna, Laverick, Sophie, Anderson, Isla, Smith, Sophie, Joyce, Joan, Janarthan, Sarala, Patel, Kamal, Ali, Mariam, Mhandu, Hilda, Rana, Aleem, Spears, Katherine, Teixeira, Joana, Mencias, Mark, Seaward, Abigail, Sousa, Jessica, Said, Nooria, Soomaroo, Mark, Raspa, Valentina, Tacouri, Asha, Reps, Nicholas, Martin, Rebecca, Samakomva, Tinashe, Selinger, Christian, Carbonell, Jenelyn, Onovira, Felicia, Quartey, Doris, L'Anson, Alice, Ashworth, Andrew, Bailey, Jessica, Dunn, Angie, Bespaloi, Gjuzel, Rasalan, Harold, Mahmood, Zahid, Campbell, Racheal, Marsh, Liane, Coughlan, Tricia, Jafar, Wisam, Marrs, Janet, McPheat, Christopher, Rahman, Monira, Davies, Sarah, Habibi, Ruth, Jessup-Dunton, Ellen, Joefield, Teishel, Layug, Reina, Patel, Vinod, Vere, Joanne, Turner, Victoria, Kilroy, Susan, Coulding, Martina, Clark, Martyn, McCormick, Jacqueline, Nisar, Attiya, Walker, Gareth, Atkins, Stacey, Growdon, Jasmine, George, Becky, McNeill, Charlotte, Reed, Bryony, Foulds, Angela, Marshall, Catherine, Allison, Michele, Dillon, Briony, Cooney, Rachel, Bennett, Lillie, Bowlas, Louise, Shariff, Sharafaath, Fraser, Aileen, Punnette, Dwayne, Lambert, Rebecca, Bishop-Hurman, Charlotte, Undrell, Elizabeth, Belfield, Katherine, Din, Said, Addleton, Catherine, Appleby, Marie, Brown, Johanna, Holding, Kathleen, Fraser, Catherine, Birkenshaw, Janice, Williams, Jodie, Maulion, Kamille, Lane, Meg, Kravale, Arita, Smith, Claud, Hooper, Patricia, deCaestecker, John, Watchorn, Olivia, Clarke, Ellie, Hayward, Chris, Inniss, Susan, Pritchard, Lucy, Rudge, Karen, Carney, Amanda, Griffee, Sarah, Andreyev, Jervoise, Babu, Sathish, Hayhurst, Caroline, Lockwood, Carol, Osborne, Lynn, Roper, Amanda, Warner, Karen, Hindle, Julia, Lawrence, Tara, Netherton, Kimberley, Watt, Caroline, Szymiczek, Kinga, Mehta, Shameer, Bell, James, Blad, William, Whitley, Lisa, Jastrub, Roman, Durai, Dhamaraj, Baker, Mark, John Sivamurugan, Elizabeth, Evans, Mim, Cummings, Fraser, Harris, Clare, Jones, Amy, Krauze, Liga, Rahmany, Sohail, Earl, Michelle, Vowles, Jenny, Torokwa, Audrey, Petrova, Mirela, Procter, Andrew, Stanley, Jo, Silvamoniz, Claudia, Bettey, Marion, Wahid, Amar, Morrison, Zoe, Thomas-Turner, Rhian, Yendle, Louise, Muller, Jennifer, Mitchell, Marcus, Kirkwood, John, Barnes, Anna, Chaudhary, Rakesh, Claridge, Melanie, Ellis, Chiara, Kemp, Cheryl, Tobi, Ogwa, Milton, Jentus, Johnston, Emma, Oblak, Metod, Winpenny, Carmen, Svensson, Marie-Louise, Godden, Jo, Ashhar, Marium, Alexander, Debbie, Covil, Kate, Derikx, Lauranne, Siakavellas, Sryros, Baxter, Helen, Robertson, Scott, Smith, Linda, Poulose, Beena, Colemam, Anne, Balint, Margareta, Rhys-Jones, Gareth, Watters, Helen, Begg, Susan, Grosalcalde, Beatriz, Coyle, Judy, Johns, Kerrie, Hughes, Rachel, Phipps, Janet, Taylor, Abigail, MacPhee, Catherine, Brooks, Suzanne, John, Jolene, Edwards, Michelle, Smith, Katie, Howard, Linda, Wood, Dianne, Muddu, Ajay, Barman, Laura, Mallinson, Janine, Neale, Tania, Ionita, Diana, Elliot, Kerry, Turnball, Alison, Thomas, Iola, Thomas, Alice, Andrews, Kelly, Sutton, Jonathon, Mulvaney Jones, Caroline, Roberts, Julia, Bishop, Jeannie, Liu, Zhigang, Le, Kaixing, Zhou, Xin, Alexander, James L, Lin, Simeng, Bewshea, Claire, Chanchlani, Neil, Nice, Rachel, McDonald, Timothy J, Lamb, Christopher A, Sebastian, Shaji, Kok, Klaartje, Lees, Charlie W, Hart, Ailsa L, Pollok, Richard C, Boyton, Rosemary J, Altmann, Daniel M, Pollock, Katrina M, Goodhand, James R, Kennedy, Nicholas A, Ahmad, Tariq, and Powell, Nick

Published
2023
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19. Prognostic Significance of Nonischemic Myocardial Fibrosis in Patients With Normal LV Volumes and Ejection-Fraction

Author

Lota, Amrit S., Tsao, Adam, Owen, Ruth, Halliday, Brian P., Auger, Dominique, Vassiliou, Vassilios S., Tayal, Upasana, Almogheer, Batool, Vilches, Silvia, Al-Balah, Amer, Patel, Akhil, Mouy, Florence, Buchan, Rachel, Newsome, Simon, Gregson, John, Ware, James S., Cook, Stuart A., Cleland, John G.F., Pennell, Dudley J., and Prasad, Sanjay K.

Published
2021
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20. 135 Effect of obesity on phenotype and cardiovascular mortality in non-ischaemic dilated cardiomyopathy

Author

Hammersley, Daniel, primary, Jones, Richard, additional, Owen, Ruth, additional, Mach, Lukas, additional, Lota, Amrit, additional, Khalique, Zohya, additional, Baruah, Resham, additional, Guha, Kaushik, additional, Ware, James, additional, Pennell, Dudley, additional, de Marvao, Antonio, additional, Tayal, Upasana, additional, Halliday, Brian, additional, and Prasad, Sanjay, additional

Published
2024
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21. O169: The impact of time to death in donors after circulatory death on recipient outcome in simultaneous pancreas-kidney transplantation

Author

Malik, Abdullah, primary, Tingle, Samuel, additional, Chung, Nicholas, additional, Owen, Ruth, additional, Mahendran, Balaji, additional, Counter, Claire, additional, Sinha, Sanjay, additional, Pettigrew, Gavin, additional, Muthasamy, Anand, additional, Sutherland, Andrew, additional, Casey, John, additional, Drage, Martin, additional, van Dellan, David, additional, Callaghan, Chris, additional, Elker, Doruk, additional, Manas, Derek, additional, Wilson, Colin, additional, and White, Steven, additional

Published
2024
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25. Assessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study

Author

Abdale, Shukri, Abbasi, Abdullah, Abusrewil, Anwar, Aghimien, Precious, Ahmed, Saeed, Ali, Akram, Ali, Amjad, Alkhoury, Jad, Allen, Patrick, Al-Rifaie, Ammar, Appleby, Richard, Arasaradnam, Ramesh, Arebi, Naila, Arms-Williams, Bradley, Ashraf, Muteeb, Au, Andrea, Avades, Tamar, Ayubi, Homira, Azhar, Saleha, Baillie, Samantha, Balarajah, Sharmili, Bancil, Aaron, Basit, Abdul, Bayati, Murad, Bell, Andrew, Berry, Alexander, Bhat, Shivaram, Bhattacharyya, Joya, Bishop, Sophia, Blackmore, Laura, Bond, Ashley, Borg-Bartolo, Simon, Botwright, Emma, Bouri, Sonia, Boyle, Stephen, Bradley, Neil, Brailsford, Fiona, Britton, Deborah, Brown, Caitlin, Butcher, Rhys, Butterworth, Jeffrey, Campbell, Rachel, Campbell, Roisin, Campbell, Iona, Carr, Ruth, Carter, Josiah, Cartlidge, Peter, Chandy, Rajiv, Chatten, Kelly, Chaudhary, Rakesh, Chee, Desmond, Cheesbrough, Jonathan, Churchhouse, Antonia, Chughtai, Sara, Clough, Jennie, Cole, Alexander, Cook, Johannah, Cooney, Rachel, Cotton, Sarah, Coulter, Archibald, Critchlow, Tamsin, Cuison, Frederic, Curran, Chris, Darie, Ana-Maria, Dart, Robin, Davwar, Pantong, Dawa, Kasamu Kabiru, Dhar, Anjan, Din, Shahida, Diong, Kok Leong, Disney, Benjamin, Dooks, Emma, Downey, Louise, D'Souza, Anita, Dyall, Lovesh, El Masri, Ali El Rida, Elias, Mary, Evans, Holli, Felwick, Richard, Finegan, Michael, Flanagan, Paul, Fofaria, Rishi, Fong, Steven Chung Ming, Fox, Richard, Fraser, Aileen, Frunza, Christian, Ghodeif, Alhassan, Ghosh, Nivedita, Gilroy, Leah, Good, Larissa, Gordon, John, Grasso, Nicola, Guéroult, Aurelién M, Gulliver, James, Guthrie, Sarah, Gwiggner, Markus, Hanna, Mina, Harlow, Christopher, Harrison, Wendy, Hart, Ailsa, Hawthorne, Barney, Henshaw, Julie, Herdman-Grant, Rosaleen, Hooper, Patricia, Howard, Willow, Hussain, Nasir, Hutton, Thomas, Htun, Aye Mya, Irving, Peter, Jagdish, Reema, Javed, Anum, Javed, Asima, Jayasooriya, Nishani, Johnson, Matthew, Johnston, Emma, Jones, Gareth-Rhys, Kanagasundaram, Cynthia, Karagkouni, Fotein, Kemp, Karen, Kemp, Cheryl, Khalil, Hesham, Khan, Najeebullah, Khasawneh, Mais, Khurshid, Bilal, King, Andrew, Kirkham, Beverley, Kirkham, Fiona, Kokwaro, Flora, Korani, Mohamed, Koumoutsos, Ioannis, Kumar, Aditi, Kuzhiyanjal, Anish John Kuriakose, Lakeland, Martyn, Laverick, Sophie, Lees, Charlie, Levell, Emma, Levison, Scott, Lim, Samuel, Lim, Yuen-Hui, Limdi, Jimmy, Lindsay, James Oliver, Lisle, Jessica, Lobo, Alan, Luber, Raphael, Lucaciu, Laura, Lyne, Holly, MacDonald, Jonathan, Mahalingam, Aarani, Mahgoub, Sara, Malakar, Ridhima, Marley, Fenella, Mason, Joy, Mazhar, Zia, McCaughan, Hannah, Naughton, Tracy, McCulloch, Adam, McIlwaine, Stuart, Meah, Nirmol, Mebarek, Leila, Mendall, Mike, Meiarasu, Radharetnas, Mir, Nasir, Mills, Tilly, Milton, Jentus, Moffat, Victoria, Moran, Gordon W, Morris, Liam, Morrison, Gary, Morrison, Graham, Mulligan, Robert, Murray, Charles, Murray, Jennifer, Musharaf, Mutwakil, Myers, Sally, Naeck-Boolauky, Pineshwari, Naranjo, Andres, Navaratnam, Janardhan, Naylor, Deanna, Nixon, Emma, Nixon, Kirsty, Nooredinvand, Hesam Ahmadi, Nosegbe, Uche, Olabintan, Olaolu, Ong Ming San, Elaine, Okpeh, Comfort, Owen, Hayley, Owen, Ruth, Palmer-Jones, Christopher, Peddada, Kalyan, Peerally, Mohammad, Perkins, Rebecca, Phillips, Frank, Pohl, Keith, Pollok, Richard, Powell, Nick, Qayyum, Farah, Qurashi, Maria, Quraishi, Mohammed Nabil, Ratcliffe, Elizabeth, Radford, Shellie, Rahmany, Sohail, Ramadan, Hanin, Ramadas, Arvind, Reddington, Anne, Riley, Tom, Rimmer, Peter, Ritchie, Susan, Roscoe, Jacqueline, Rosiou, Konstantina, Rowland, Siobhan, Sabine, Joseph, Saifuddin, Aamir, Samaan, Mark, Sarkar, Priya, Sarwar, Shahzad, Sasegbon, Ayodele, Saunders, Jayne, Sebepos-Rogers, Gregory, Seenan, John Paul, Selinger, Christian, Serna, Solange, Sethi, Sonika, Shale, Matthew, Shenderey, Richard, Shenoy, Achuth, Sherifat, Yousuf, Sheth, Roosey, Siakavellas, Spyros, Sikafi, Rafid, Singh, Amar, Singh, Salil, Singh, Updesh, Sivaji, Ganesh, Smith, Philip, Speight, R Alexander, Spence, Andy, Stansfield, Catherine, Steed, Helen, Suseeharan, Kishaani, Tabuso, Maria, Taucius, Donatas, Taylor, Joanne, Thakor, Amit, Tham, Tony, Townsend, Gill, Townsend, Tristan, Troth, Thomas, Tunney, Ruth, Turner, Kelly, Umar, Nosheen, Vakeeswarasarma, Vithushan, Verma, Ajay M, Wallace, Hazel, Wallis, Katharina, Walton, Hannah, Wang, Bo, Warner, Eleanor, Watson, Callum, Watson, Eleanor, Wen, Susie, Widlak, Monika, Williams, Maureen, Woods, Amy, Younge, Lisa, Zafar, Mansoor, Sebastian, Shaji, Walker, Gareth J, Kennedy, Nicholas A, Conley, Thomas E, Patel, Kamal V, Subramanian, Sreedhar, Kent, Alexandra J, Segal, Jonathan P, Brookes, Matthew J, Bhala, Neeraj, Gonzalez, Haidee A, Hicks, Lucy C, Mehta, Shameer J, and Lamb, Christopher A

Published
2021
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26. Late-Gadolinium Enhancement Interface Area and Electrophysiological Simulations Predict Arrhythmic Events in Patients With Nonischemic Dilated Cardiomyopathy

Author

Balaban, Gabriel, Halliday, Brian P., Porter, Bradley, Bai, Wenjia, Nygåard, Ståle, Owen, Ruth, Hatipoglu, Suzan, Ferreira, Nuno Dias, Izgi, Cemil, Tayal, Upasana, Corden, Ben, Ware, James, Pennell, Dudley J., Rueckert, Daniel, Plank, Gernot, Rinaldi, Christopher A., Prasad, Sanjay K., and Bishop, Martin J.

Published
2021
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29. "I want to have a path" : an exploratory study of parent experience of early autism diagnosis in Massachusetts and Central Scotland

Author

Glynne-Owen, Ruth Elizabeth, Cebula, Katie, and MacLeod, Gale

Subjects
618.92, autism, diagnosis, parent experience, preschool
Abstract

Parents of children with autism have been identified across research as having unique experiences in comparison to parents of children with other disabilities. The focus to date has been on identifying factors impacting on parental well-being post-diagnosis, with some more recent studies looking more specifically at parent experience of the diagnostic process. However, there is less literature that explores the impact that this diagnosis may have on parental perspectives of, and aspirations for, their child. In addition, within this current research, little is known about how parents of toddlers make meaning of their situation pre and post-diagnosis, with limited literature so far that looks at the influence that geographical location may have on this. As an exploratory, qualitative study of parent experience of early autism diagnosis in Massachusetts and central Scotland, this thesis aimed to bridge this gap by investigating parents’ experience in these early years, in two similar, yet contrasting settings with significant differences in policy and practice. Utilising Blumer’s (1969) principles of symbolic interactionism, this thesis examined the factors that had an effect on participants’ meaning making, drawing on extended premises of SI (Snow, 2001; Stryker, 2008) to explore the extent to which structural and social influences in each country may have impacted on this. It looked at the similarities and differences between parents’ experiences of: the autism diagnostic process; access to, and engagement with, post-diagnosis services; changes in perceptions of autism over time; and whether perspectives of, and aspirations for, their child altered since diagnosis. All 18 participants (14 mothers and 4 fathers) had a child (13 boys and 5 girls) under 5 years old with a diagnosis of autism. Data were generated through semi-structured interviews, using open coding to group initial categories, before moving into interpretive, inductive analysis to identify wider themes. Findings highlighted key differences between policy and practice, which influenced parent experience in a number of ways. In particular, the differences between the services and support available to young children with autism and their families in each location appeared to have a significant impact on participants. However, this study also concluded that, in spite of differences in policy and practice, there were also a number of similarities in the ways in which parents made meaning and sense of their child’s diagnosis. Interaction with other parents (both face to face and online) had a strong influence on this, alongside parents’ exposure to media portrayals of autism, which were similar in both locations. Conversely, in spite of their experiences with a wide range of professionals, these interactions had a more limited effect overall on the perspectives that parents developed of their child. In addition, in spite of recognising previously held beliefs regarding stigma and stereotype in autism, all parents in this study actively rejected these perceptions after receiving a diagnosis for their child. Overall, data reflected a shared understanding of autism that crossed geographical and structural boundaries, with parents from both countries experiencing the same hopes, aspirations and fears for their child’s future. These findings may have implications for policy considerations and for services in both locations delivering pre and post-diagnostic support, with potential for more positive outcomes overall for those receiving an early diagnosis for their child.

Published
2016

34. Comparing the long-term outcomes in chronic coronary syndrome patients with prior ST-segment and non-ST-segment elevation myocardial infarction: findings from the TIGRIS registry

Author

Krishnamurthy, Sibi N, primary, Pocock, Stuart, additional, Kaul, Prashant, additional, Owen, Ruth, additional, Goodman, Shaun G, additional, Granger, Christopher B, additional, Nicolau, Jose Carlos, additional, Simon, Tabassome, additional, Westermann, Dirk, additional, Yasuda, Satoshi, additional, Andersson, Karolina, additional, Brandrup-Wognsen, Gunnar, additional, Hunt, Phillip R, additional, Brieger, David B, additional, and Cohen, Mauricio G, additional

Published
2023
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35. Cardiovascular magnetic resonance predictors of heart failure in hypertrophic cardiomyopathy: the role of myocardial replacement fibrosis and the microcirculation

Author

Raphael, Claire E., Mitchell, Frances, Kanaganayagam, Gajen Sunthar, Liew, Alphonsus C., Di Pietro, Elisa, Vieira, Miguel Silva, Kanapeckaite, Lina, Newsome, Simon, Gregson, John, Owen, Ruth, Hsu, Li-Yueh, Vassiliou, Vassilis, Cooper, Robert, MRCP, Aamir Ali, Ismail, Tevfik F., Wong, Brandon, Sun, Kristi, Gatehouse, Peter, Firmin, David, Cook, Stuart, Frenneaux, Michael, Arai, Andrew, O’Hanlon, Rory, Pennell, Dudley J., and Prasad, Sanjay K.

Published
2021
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37. Sex Differences in the Clinical Presentation and Natural History of Dilated Cardiomyopathy

Author

Owen, Ruth, primary, Buchan, Rachel, additional, Frenneaux, Michael, additional, Jarman, Julian W.E., additional, Baruah, Resham, additional, Lota, Amrit S., additional, Halliday, Brian P., additional, Roberts, Angharad M., additional, Izgi, Cemil, additional, Van Spall, Harriette G.C., additional, Michos, Erin D., additional, McMurray, John J.V., additional, Januzzi, James L., additional, Pennell, Dudley J., additional, Cook, Stuart A., additional, Ware, James S., additional, Barton, Paul J., additional, Gregson, John, additional, Prasad, Sanjay K., additional, and Tayal, Upasana, additional

Published
2023
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38. Phenotype, outcomes and natural history of early‐stage non‐ischaemic cardiomyopathy

Author

Hammersley, Daniel J., primary, Jones, Richard E., additional, Owen, Ruth, additional, Mach, Lukas, additional, Lota, Amrit S., additional, Khalique, Zohya, additional, De Marvao, Antonio, additional, Androulakis, Emmanuel, additional, Hatipoglu, Suzan, additional, Gulati, Ankur, additional, Reddy, Rohin K., additional, Yoon, Won Young, additional, Talukder, Suprateeka, additional, Shah, Riya, additional, Baruah, Resham, additional, Guha, Kaushik, additional, Pantazis, Antonis, additional, Baksi, A. John, additional, Gregson, John, additional, Cleland, John G. F., additional, Tayal, Upasana, additional, Pennell, Dudley J., additional, Ware, James S., additional, Halliday, Brian P., additional, and Prasad, Sanjay K., additional

Published
2023
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39. Assessing the association between genetic and phenotypic features of dilated cardiomyopathy and outcome in patients with coronary artery disease

Author

Jones, Richard E., primary, Hammersley, Daniel J., additional, Zheng, Sean, additional, McGurk, Kathryn A., additional, de. Marvao, Antonio, additional, Theotokis, Pantazis I., additional, Owen, Ruth, additional, Tayal, Upasana, additional, Rea, Gillian, additional, Hatipoglu, Suzan, additional, Buchan, Rachel J., additional, Mach, Lukas, additional, Curran, Lara, additional, Lota, Amrit S., additional, Simard, François, additional, Reddy, Rohin K., additional, Talukder, Suprateeka, additional, Yoon, Won Young, additional, Vazir, Ali, additional, Pennell, Dudley J., additional, O'Regan, Declan P., additional, Baksi, A. John, additional, Halliday, Brian P., additional, Ware, James S., additional, and Prasad, Sanjay K., additional

Published
2023
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41. Long-term outcomes among stable post-acute myocardial infarction patients living in rural versus urban areas: insights from the prospective, observational TIGRIS registry

Author

Nicolau, Jose Carlos, primary, Owen, Ruth, additional, Furtado, Remo H M, additional, Goodman, Shaun G, additional, Granger, Christopher B, additional, Cohen, Mauricio G, additional, Westermann, Dirk, additional, Yasuda, Satoshi, additional, Simon, Tabassome, additional, Hedman, Katarina, additional, Hunt, Phillip R, additional, Brieger, David B, additional, and Pocock, Stuart J, additional

Published
2023
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42. Assessing the association between genetic and phenotypic features of dilated cardiomyopathy and outcome in patients with coronary artery disease.

Author

Jones, Richard E., Hammersley, Daniel J., Zheng, Sean, McGurk, Kathryn A., de Marvao, Antonio, Theotokis, Pantazis I., Owen, Ruth, Tayal, Upasana, Rea, Gillian, Hatipoglu, Suzan, Buchan, Rachel J., Mach, Lukas, Curran, Lara, Lota, Amrit S., Simard, François, Reddy, Rohin K., Talukder, Suprateeka, Yoon, Won Young, Vazir, Ali, and Pennell, Dudley J.

Subjects
CORONARY artery disease, DILATED cardiomyopathy, VENTRICULAR ejection fraction, PHENOTYPES, VENTRICULAR remodeling
Abstract

Aims: To examine the relevance of genetic and cardiovascular magnetic resonance (CMR) features of dilated cardiomyopathy (DCM) in individuals with coronary artery disease (CAD). Methods and results: This study includes two cohorts. First, individuals with CAD recruited into the UK Biobank (UKB) were evaluated. Second, patients with CAD referred to a tertiary centre for evaluation with late gadolinium enhancement (LGE)‐CMR were recruited (London cohort); patients underwent genetic sequencing as part of the research protocol and long‐term follow‐up. From 31 154 individuals with CAD recruited to UKB, rare pathogenic variants in DCM genes were associated with increased risk of death or major adverse cardiac events (hazard ratio 1.57, 95% confidence interval [CI] 1.22–2.01, p < 0.001). Of 1619 individuals with CAD included from the UKB CMR substudy, participants with a rare variant in a DCM‐associated gene had lower left ventricular ejection fraction (LVEF) compared to genotype negative individuals (mean 47 ± 10% vs. 57 ± 8%, p < 0.001). Of 453 patients in the London cohort, 63 (14%) had non‐infarct pattern LGE (NI‐LGE) on CMR. Patients with NI‐LGE had lower LVEF (mean 38 ± 18% vs. 48 ± 16%, p < 0.001) compared to patients without NI‐LGE, with no significant difference in the burden of rare protein altering variants in DCM‐associated genes between groups (9.5% vs. 6.7%, odds ratio 1.5, 95% CI 0.4–4.3, p = 0.4). NI‐LGE was not independently associated with adverse clinical outcomes. Conclusion: Rare pathogenic variants in DCM‐associated genes impact left ventricular remodelling and outcomes in stable CAD. NI‐LGE is associated with adverse remodelling but is not an independent predictor of outcome and had no rare genetic basis in our study. [ABSTRACT FROM AUTHOR]

Published
2024
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44. Abstract 13907: Patients With NSTEMI Are at Higher Risk, Have Worse Outcomes, but Less Intense Cardiology Follow-up 1-3 Years Post-discharge: Findings From the TIGRIS Registry

Author

Krishnamurthy, Sibi N, Pocock, Stuart, Kaul, Prashant, Owen, Ruth, Chen, Jiyan, Goodman, Shaun G, Granger, Christopher B, Nicolau, Jose C, Simon, Tabassome, Westermann, Dirk, Yasuda, Satoshi, Andersson-Sundell, Karolina, Brandrup-Wognsen, Gunnar, Hunt, Phillip, Brieger, David, and Cohen, Mauricio G

Published
2020
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46. Anticoagulation Strategies in Non-Critically Ill Patients Hospitalized with COVID-19: A Randomized Clinical Trial

Author

Stone, Gregg W., primary, Farkouh, Michael E., additional, Lala, Anuradha, additional, Tinuoye, Elizabeth, additional, Dressler, Ovidiu, additional, Moreno, Pedro R., additional, Palacios, Igor F., additional, Goodman, Shaun G., additional, Esper, Rodrigo B., additional, Abizaid, Alexandre, additional, Varade, Deepak, additional, Betancur, Juan F., additional, Ricalde, Alejandro, additional, Payro, Gerardo, additional, Castellano, José María, additional, Hung, Ivan FN, additional, Nadkarni, Girish N., additional, Giustino, Gennaro, additional, Godoy, Lucas C., additional, Feinman, Jason, additional, Camaj, Anton, additional, Bienstock, Solomon W., additional, Furtado, Remo H.M., additional, Granada, Carlos, additional, Bustamante, Jessica, additional, Peyra, Carlos, additional, Contreras, Johanna, additional, Owen, Ruth, additional, Bhatt, Deepak L., additional, Pocock, Stuart J., additional, Fuster, Valentin, additional, Lala, Anu, additional, Paul, Jonathan, additional, Pyo, Robert, additional, Baber, Usman, additional, Suh, Jason, additional, Saggar, Suraj, additional, Srivatsa, Sanjay, additional, Coylewright, Megan, additional, Chapparo, Sandra, additional, Melo, Jairo, additional, Keller, Norma, additional, Llanos, Alexander, additional, Chiu, Edwin, additional, Fahid, Ibrahim, additional, The, Angela, additional, Esper, Rodrigo Barbosa, additional, Ghetti Cabral, Ricardo Mauro, additional, Pompilio, Mauricio Antonio, additional, Cordeiro de Paula, Leonardo Jorge, additional, Airton de Arruda, Jose, additional, Filho, Roberto Kalil, additional, Faillace, Bruno, additional, Avancini Caramori, Paulo Ricardo, additional, da Silva Junior, Delcio Goncalves, additional, Neto, Eduardo Kowalski, additional, Nascif, Gibran Bhering, additional, Baccaro, Bruno Mendonca, additional, Cesar Cavalcanti, Rafael Rebelo, additional, Moraes Junior, Joao Batista, additional, Betancur, Juan Felipe, additional, Echeverri, Dario, additional, Beltran, Fernan Mendoza, additional, Renowistki Zabarain, Carlos Ramon, additional, Martinez Bula, Eduardo Antonio, additional, Fernandez, Angela María, additional, Melendez Flórez, Hector Julio, additional, Osorio, Wilder Castano, additional, Clavijo Moldón, Absalon Antonio, additional, Moreno, Antonio Figueredo, additional, Wong, Chun-Ka, additional, Varma, Madhumati, additional, Khanna, Aman, additional, Nikam, Prasad, additional, Bangi, Ashpak, additional, Gupta, Jugal Bihari, additional, Bhandari, Sudhir, additional, Sengupta, Shantanu, additional, Bhattacharya, Meenakshi, additional, Mehta, Nihar, additional, Aggarwal, Deepesh, additional, Uppe, Abhay, additional, Calcagno, Andrea, additional, Querini, Patrizia Rovere, additional, Narducci, Maria Lucia, additional, Guerrero, Jessica Paola, additional, Elizalde, Ivan, additional, Bello, Hector Herrera, additional, Cabrera, Otto Tavera, additional, Portano, Julieta Morales, additional, Riedel, Patricia Aubanel, additional, Llamas Esperon, Guillermo Antonio, additional, Guarena Casillas, Jorge Armando, additional, Azpiri, Jose Ramon, additional, Calvillo, Jorge Carrillo, additional, Lopez, Roberto Dominguez, additional, Barreto, Nancy Quezada, additional, Jaramillo, Ricardo, additional, Sokolski, Mateusz, additional, Fernandez, Paula Villares, additional, Moya Mateo, Eva Maria, additional, Varona Arche, Jose Felipe, additional, Mateo, Patricia Fanlo, additional, and Garcia Lomas, Mercedes Villareal, additional

Published
2023
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47. Comprehensive Phenotypic Characterization of Late Gadolinium Enhancement Predicts Sudden Cardiac Death in Coronary Artery Disease

Author

Jones, Richard E, Zaidi, Hassan A, Hammersley, Daniel J, Hatipoglu, Suzan, Owen, Ruth, Balaban, Gabriel, de Marvao, Antonio, Simard, François, Lota, Amrit S, Mahon, Ciara, Almogheer, Batool, Mach, Lukas, Musella, Francesca, Chen, Xiuyu, Gregson, John, Lazzari, Laura, Ravendren, Andrew, Leyva, Francisco, Zhao, Shihua, Vazir, Ali, Lamata, Pablo, Halliday, Brian P, Pennell, Dudley J, Bishop, Martin J, Prasad, Sanjay K, Jones, Richard E, Zaidi, Hassan A, Hammersley, Daniel J, Hatipoglu, Suzan, Owen, Ruth, Balaban, Gabriel, de Marvao, Antonio, Simard, François, Lota, Amrit S, Mahon, Ciara, Almogheer, Batool, Mach, Lukas, Musella, Francesca, Chen, Xiuyu, Gregson, John, Lazzari, Laura, Ravendren, Andrew, Leyva, Francisco, Zhao, Shihua, Vazir, Ali, Lamata, Pablo, Halliday, Brian P, Pennell, Dudley J, Bishop, Martin J, and Prasad, Sanjay K

Abstract

BACKGROUND: Late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) offers the potential to noninvasively characterize the phenotypic substrate for sudden cardiac death (SCD). OBJECTIVES: The authors assessed the utility of infarct characterization by CMR, including scar microstructure analysis, to predict SCD in patients with coronary artery disease (CAD). METHODS: Patients with stable CAD were prospectively recruited into a CMR registry. LGE quantification of core infarction and the peri-infarct zone (PIZ) was performed alongside computational image analysis to extract morphologic and texture scar microstructure features. The primary outcome was SCD or aborted SCD. RESULTS: Of 437 patients (mean age: 64 years; mean left ventricular ejection fraction [LVEF]: 47%) followed for a median of 6.3 years, 49 patients (11.2%) experienced the primary outcome. On multivariable analysis, PIZ mass and core infarct mass were independently associated with the primary outcome (per gram: HR: 1.07 [95% CI: 1.02-1.12]; P = 0.002 and HR: 1.03 [95% CI: 1.01-1.05]; P = 0.01, respectively), and the addition of both parameters improved discrimination of the model (Harrell's C-statistic: 0.64-0.79). PIZ mass, however, did not provide incremental prognostic value over core infarct mass based on Harrell's C-statistic or risk reclassification analysis. Severely reduced LVEF did not predict the primary endpoint after adjustment for scar mass. On scar microstructure analysis, the number of LGE islands in addition to scar transmurality, radiality, interface area, and entropy were all associated with the primary outcome after adjustment for severely reduced LVEF and New York Heart Association functional class of >1. No scar microstructure feature remained associated with the primary endpoint when PIZ mass and core infarct mass were added to the regression models. CONCLUSIONS: Comprehensive LGE characterization independently predicted SCD risk beyond conventional predictors used in imp

Published
2023

48. Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study

Author

Liu, Zhigang, primary, Le, Kaixing, additional, Zhou, Xin, additional, Alexander, James L, additional, Lin, Simeng, additional, Bewshea, Claire, additional, Chanchlani, Neil, additional, Nice, Rachel, additional, McDonald, Timothy J, additional, Lamb, Christopher A, additional, Sebastian, Shaji, additional, Kok, Klaartje, additional, Lees, Charlie W, additional, Hart, Ailsa L, additional, Pollok, Richard C, additional, Boyton, Rosemary J, additional, Altmann, Daniel M, additional, Pollock, Katrina M, additional, Goodhand, James R, additional, Kennedy, Nicholas A, additional, Ahmad, Tariq, additional, Powell, Nick, additional, Islam, Madiha, additional, Croft, Nick, additional, Cipriano, Bessie, additional, Francia, Caroline, additional, Khalid, Nosheen, additional, Kingston, Ashley, additional, Lee, Irish, additional, Lehmann, Anouk, additional, Naik, Kinnari, additional, Samuels, Kevin, additional, Plaatjies, Nicolene, additional, Khatun, Hafiza, additional, Bokth, Farjana, additional, Pabriaga, Elise, additional, Saich, Rebecca, additional, Cousins, Hayley, additional, Fraser, Wendy, additional, Thomas, Rachel, additional, Brown, Matthew, additional, White, Benjamin, additional, Kirkineziadis, Nikolaos, additional, Tilley, Bernadette, additional, Porter, Pennie, additional, Bryant, Rachel, additional, Robaczewska, Natalia, additional, Muhammed, Rafeeq, additional, Bi, Rehana, additional, Cotter, Catherine, additional, Grove, Jayne, additional, Hong, Kate, additional, Howman, Ruth, additional, Mitchell, Monica, additional, Clayton, Sophie, additional, Rogers, Louise, additional, Sultan, Sugrah, additional, Rooney, Melanie, additional, Cottrill, Charlotte, additional, Singh, Salil, additional, Dawe, Chris, additional, Hull, Robert, additional, Silva, Natalie, additional, Chadwick, Julie, additional, Robertson, Laura, additional, Manning, Jonathan, additional, Finlayson, Lauren, additional, Roebuck, Allison, additional, Dawson, Joy, additional, Sonwalkar, Sunil, additional, Chambers, Naomi, additional, Robinson, Matthew, additional, Haigh, Andrew, additional, Matapure, Lear, additional, Raine, Tim, additional, George, Varun, additional, Kapizioni, Christina, additional, Strongili, Konstantina, additional, Thompson, Tina, additional, Ahmed, Mohamed, additional, Kontos, Christos, additional, Dawson, Claire, additional, Bourges, Christophe, additional, Barbutti, Isabella, additional, Gozzard, Megan E, additional, Hendy, Philip, additional, Bull, Rhian, additional, Costa, Patricia, additional, Davey, Lisa, additional, Hannington, Hayley, additional, Nundlall, Kribashnie, additional, Martins, Catarina, additional, Avanzi, Laura, additional, Carungcong, Jaime, additional, Barr, Sabrina, additional, Appleby, Richard, additional, Johnson, Emma, additional, Shakweh, Eathar, additional, Phillis, Kath, additional, Gascoyne, Rachel, additional, Crowder, Amanda, additional, Whileman, Amanda, additional, London, Ian, additional, Grounds, Jenny, additional, Martin, Emmeline, additional, Pajak, Susie, additional, Price, Jude, additional, Cawley, Kathryn, additional, Powell, Sandra, additional, Kearsley, Nichola, additional, Dhar, Anjan, additional, Brown, Ellen, additional, Cowton, Amanda, additional, Stamp, Kimberley, additional, Warner, Ben, additional, Stuart, Carmel, additional, Lacey, Louise, additional, de Silva, Shanika, additional, Allcock, Clare, additional, Harvey, Philip, additional, Jones, Lesley, additional, Cooke, Elise, additional, Slater, Jayne, additional, King, Dominic, additional, Brooks, Johanne, additional, Baker, Pearl, additional, Beadle, Hannah, additional, Cruz, Carina, additional, Potter, Debbie, additional, Collum, Joe, additional, Masters, Farzana, additional, Kumar, Aashish, additional, Coetzee, Samantha, additional, Peiu, Mihaela, additional, Icke, Becky, additional, Williams, Jill, additional, Raj, Meena, additional, Gaynor, Edward, additional, Chadokufa, Sibongile, additional, Huggett, Bonita, additional, Meghari, Hamza, additional, El-Khouly, Sara, additional, Kiparissi, Fevronia, additional, Girshab, Waffa, additional, Russell-Walker, Lynda, additional, Jackson, Christopher, additional, Sidler, Sara, additional, Claridge, Andrew, additional, Fowler, Emily, additional, McCafferty, Laura, additional, Haxton, Lesley, additional, Irving, Peter, additional, Christodoulides, Karolina, additional, Clifford, Angela, additional, Dawson, Patrick, additional, Honap, Sailish, additional, Lim, Samuel, additional, Luber, Raphael, additional, Mahiouz, Karina, additional, Meade, Susanna, additional, Raymode, Parizade, additional, Reynolds, Rebecca, additional, Stanton, Anna, additional, Tripoli, Sherill, additional, Hare, Naomi, additional, Odukwe, Sopuluchukwu, additional, Balachandran, Senthuran, additional, North, Emma, additional, North, Jessica, additional, Browne, Bria, additional, Cordle, Jessica, additional, Jameson, Ella, additional, Siaw, Yih Harn, additional, Manzano, Lane, additional, Segal, Jonathan, additional, Al-Bakir, Ibrahim, additional, Khakoo, Imran, additional, Portukhay, Sofiya, additional, Thoua, Nora, additional, Davidson, Katherine, additional, Miah, Jagrul, additional, Canclini, Lisa, additional, Hall, Alex, additional, Furreed, Hassina, additional, Mitchell-Inwang, Christine, additional, Hayes, Melony, additional, Myers, Sally, additional, Talbot, Alison, additional, Turnbull, Jack, additional, Whitehead, Emma, additional, Stamp, Katie, additional, Pattinson, Alison, additional, Mathew, Verghese, additional, Sherris, Leanne, additional, Wilcox, Julie, additional, Ramachandran, Sankaranarayanan, additional, Robertson, Hayley, additional, Harvey, Angela, additional, Hicks, Lucy, additional, Byrne, Tara-Marie, additional, Cabreros, Leilani, additional, Downing-Wood, Hannah, additional, Hunter, Sophie, additional, Saifuddin, Mohammad Aamir, additional, Prabhudev, Hemanth, additional, Balarajah, Sharmili, additional, Krucznski, Jan, additional, Driva, Kalliopi, additional, D'Mello, Andrea, additional, Shah, Parith, additional, Castro-Seoane, Rocio, additional, Ibraheim, Hajir, additional, Constable, Laura E, additional, Lo, Jonathan W, additional, Torkizadeh, Melissa, additional, Hermangild, Sherine K, additional, Sutherland, Helen, additional, Wilhelmsen, Elva, additional, Mackintosh, Katherine, additional, Verma, Ajay M, additional, Sebastian, Juliemol, additional, Peerally, Mohammad Farhad, additional, Guerdette, Anne-marie, additional, Coburn, Susan, additional, Novem lam, Ching Yee, additional, Durrant, Donna, additional, Schaefer, Belinda, additional, Serna, Solange, additional, Shahzad, Muhammad, additional, Kent, Alexandra, additional, Choong, Lee Meng, additional, Pantaloni, Benedetta, additional, Ravdas, Pantelis, additional, Vadamalayan, Babu, additional, Foley, Stephen, additional, Arnold, Becky, additional, Heeley, Cheryl, additional, Lovegrove, Wayne, additional, Sowton, Donna, additional, Allsop, Lynne, additional, Gregory, Heidi, additional, Gill, Mandy, additional, Holmes, Megan, additional, Balan, Valeria, additional, Smith, Susan, additional, Turner, Sarah, additional, Smith, Philip J, additional, Steel, Alan, additional, Bretland, Giovanna, additional, King, Sarah, additional, Lofthouse, Martina, additional, Rigby, Lindsey, additional, Subramanian, Sreedhar, additional, Tyrer, David, additional, Martin, Kate, additional, Probert, Christopher, additional, Kamperidis, Nikolaos, additional, Adedoyin, Temi, additional, Baden, Manisha, additional, Brown, Jeannette, additional, Chacko, Feba, additional, Young, Lisa, additional, Cicchetti, Michela, additional, Saifuddin, Mohammad, additional, Yesupatham, Priya, additional, Gowda, Rohit, additional, Williams, Maureen, additional, Kemp, Karen, additional, Akhand, Rima, additional, Gray, Glaxy, additional, John, Anu, additional, John, Maya, additional, Mohammed, Tasnim, additional, Sathe, Diamond, additional, Jones, Natasha, additional, Soren, Jennifer, additional, Sprakes, Michael, additional, Burton, Julie, additional, Kane, Patricia, additional, Lupton, Stephanie, additional, Bartholomew, Jacqueline, additional, Denis, Elizabeth, additional, Daniels, Alison, additional, MacFaul, George, additional, Scaletta, Diane, additional, Siamia, Loria, additional, Williams, Felicity, additional, Green, Chloe, additional, Ver, Zeljka, additional, Lamb, Chris, additional, Doona, Mary, additional, Hogg, Ashleigh, additional, Jeffrey, Lesley, additional, King, Andrew, additional, Speight, R Alexander, additional, Doyle, Jennifer, additional, Owen, Ruth, additional, Haworth, Jenny, additional, Patterson, Linda, additional, Varnaulasingam, Vithusa, additional, Mowat, Craig, additional, Rice, Debbie, additional, MacFarlane, Susan, additional, MacLeod, Anne, additional, Mohammed, Samera, additional, Murray, Shona, additional, Elliott, Anne, additional, Anne Morris, Mary, additional, Coke, Louise, additional, Hindle, Grace, additional, Kolokouri, Eirini, additional, Wright, Catherine, additional, Lee, Claire, additional, Ward, Nicola, additional, Dann, Adele, additional, Lockett, Melanie, additional, Cranfield, Charlotte, additional, Jennings, Louise, additional, Srivastava, Ankur, additional, Ward, Lana, additional, Jeynes, Nouf, additional, Ranga, Poonam, additional, Rajasekhar, Praveen, additional, Gallagher, Lisa, additional, Ward, Jill, additional, Basnett, Rae, additional, Murphy, Judy, additional, Parking, Lauren, additional, Lawson, Emma, additional, Short, Stacey, additional, Devadason, David, additional, Moran, Gordon, additional, Khan, Neelam, additional, Tarr, Lauren, additional, Olivia, Charmaine, additional, Warbarton, Samantha, additional, Kelly, Sian, additional, Limdi, Jimmy, additional, Goulden, Kay, additional, Javed, Asad, additional, McKenzie, Lauren, additional, Melville, Julie, additional, Liu, Eleanor, additional, Sabine, Joseph, additional, Jacob, Patricia, additional, McSorland, Denise, additional, Schofield, Nick, additional, Cornwall, Lisa, additional, Quirke, James, additional, Crook, Emma, additional, Turner, Anne, additional, Bhandari, Pradeep, additional, Baker-Moffatt, Michelle, additional, Dash, Joanne, additional, Le Poidevin, Alison, additional, Downe, Hayley, additional, Bombeo, Lucille, additional, Blackman, Helen, additional, Smith, Rebecca, additional, Wiles, Alan, additional, Bloxham, Hannah, additional, Dias, Jose, additional, Nadar, Evelyn, additional, Curgenven, Hollie, additional, Gilham, Ellie, additional, Macdonald, Jonathan, additional, Finan, Shona, additional, McMeeken, Faye, additional, Mahmood, Misbah, additional, Shields, Stephanie, additional, Seenan, John Paul, additional, DeSilva, Des, additional, Malkakorpi, Susanna, additional, Carson, Rachel, additional, Lawrence, Holly, additional, Boateng, Ofori, additional, Kpodo, Felix, additional, Whiteoak, Simon, additional, Edger-Earley, Kelli, additional, Vamplew, Luke, additional, Samways, Joanna, additional, Roffe, Sue, additional, Ingram, Sarah, additional, James, Joel, additional, Botfield, Sharon, additional, Hammonds, Fiona, additional, James, Clare, additional, Berry, Zoe, additional, Aspinall, Gemma, additional, Hawkins, Sarah, additional, Parkinson, Marian, additional, Gardner-Thorpe, Helen, additional, Marriott, Suzie, additional, Redstone, Clare, additional, Windak, Halina, additional, Adam, Ana-Marie, additional, Mabb, Hannah, additional, Stevenson, Emma, additional, Record, Jessica, additional, Murray, Charles, additional, Diaba, Cynthia, additional, Joseph, Fexy, additional, Pakou, Glykeria, additional, Gleeson, Yvonne, additional, Nunag, Annalyn, additional, Berrill, James, additional, Stroud, Natalie, additional, Pothecary, Carla, additional, Roche, Lisa, additional, Turner, Keri, additional, Deering, Lisa, additional, Israel, Lynda, additional, Baker, Evelyn, additional, Nash, Maxine, additional, Fagbemi, Andrew, additional, Jennings, Felicia, additional, Mayor, Imelda, additional, Wilson, Jill, additional, Wheeler, Alice, additional, Phillips, Nicola, additional, Gordon, John, additional, Levell, Emma, additional, Zagalo, Silvia, additional, Hoad, Ina, additional, Anil, Bindu, additional, Russell, Richard, additional, Henderson, Paul, additional, Millar, Margaret, additional, Alexakis, Christopher, additional, Michalak, Natalia, additional, Marriott, Cheryl, additional, Stone, Sarah, additional, Pristopan, Veronika, additional, Saunders, John, additional, Burton, Helen, additional, Cambridge, Vanessa, additional, Clark, Tonia, additional, Ekblad, Charlotte, additional, Hierons, Sarah, additional, Katebe, Joyce, additional, Saunsbury, Emma, additional, Perry, Rachel, additional, Brookes, Matthew, additional, Davies, Kathryn, additional, Green, Marie, additional, Plumbe, Ann, additional, Ormerod, Clare, additional, Christensen, Helen, additional, Howlett, Hannah, additional, Keen, Anne, additional, Ogor, Jonathan, additional, Greenhaigh, Marie, additional, Knowles, Karen, additional, Yin, Shanzi, additional, Poulaka, Maria, additional, Anthony, Alpha, additional, Newitt, Emily, additional, Trim, Fiona, additional, Casey, Ruth, additional, Seymour, Katherine, additional, Reed, Catherine, additional, Joy, Lijo, additional, Fogden, Edward, additional, Russell, Kalisha, additional, Hussain, Samia, additional, Phillips, Anne, additional, Abdulla, Muaad, additional, Butterworth, Jeff, additional, Adams, Colene, additional, Carnahan, Mandy, additional, Buckingham, Elizabeth, additional, Childs, Danielle, additional, Magness, Alison, additional, Stickley, Jo, additional, Motherwell, Nichola, additional, Tonks, Louise, additional, Gibson, Hannah, additional, Wistance, Kate, additional, Thomas, Caradog, additional, Brinkworth, Elaine, additional, Connor, Lynda, additional, Cook, Amanda, additional, Rees, Tabitha, additional, Harford, Rachel, additional, Farley, Sean, additional, Jones, Marie, additional, Wesley, Emma, additional, Moss, Alison, additional, Lucas, Jacob, additional, Lorimer, Claire, additional, Oleary, Maria, additional, Dixon, Maxine, additional, Goodchild, Fiona, additional, Twenlow, Rebecca, additional, Pawley, Corinne, additional, Ramadas, Arvind, additional, Tregonning, Julie, additional, Okeke, Olaku, additional, Jackson, Wendy, additional, Koumoutsos, Ioannis, additional, George, Viji, additional, Kunhunny, Swapna, additional, Laverick, Sophie, additional, Anderson, Isla, additional, Smith, Sophie, additional, Joyce, Joan, additional, Janarthan, Sarala, additional, Patel, Kamal, additional, Ali, Mariam, additional, Mhandu, Hilda, additional, Rana, Aleem, additional, Spears, Katherine, additional, Teixeira, Joana, additional, Mencias, Mark, additional, Seaward, Abigail, additional, Sousa, Jessica, additional, Said, Nooria, additional, Soomaroo, Mark, additional, Raspa, Valentina, additional, Tacouri, Asha, additional, Reps, Nicholas, additional, Martin, Rebecca, additional, Samakomva, Tinashe, additional, Selinger, Christian, additional, Carbonell, Jenelyn, additional, Onovira, Felicia, additional, Quartey, Doris, additional, L'Anson, Alice, additional, Ashworth, Andrew, additional, Bailey, Jessica, additional, Dunn, Angie, additional, Bespaloi, Gjuzel, additional, Rasalan, Harold, additional, Mahmood, Zahid, additional, Campbell, Racheal, additional, Marsh, Liane, additional, Coughlan, Tricia, additional, Jafar, Wisam, additional, Marrs, Janet, additional, McPheat, Christopher, additional, Rahman, Monira, additional, Davies, Sarah, additional, Habibi, Ruth, additional, Jessup-Dunton, Ellen, additional, Joefield, Teishel, additional, Layug, Reina, additional, Patel, Vinod, additional, Vere, Joanne, additional, Turner, Victoria, additional, Kilroy, Susan, additional, Coulding, Martina, additional, Clark, Martyn, additional, McCormick, Jacqueline, additional, Nisar, Attiya, additional, Walker, Gareth, additional, Atkins, Stacey, additional, Growdon, Jasmine, additional, George, Becky, additional, McNeill, Charlotte, additional, Reed, Bryony, additional, Foulds, Angela, additional, Marshall, Catherine, additional, Allison, Michele, additional, Dillon, Briony, additional, Cooney, Rachel, additional, Bennett, Lillie, additional, Bowlas, Louise, additional, Shariff, Sharafaath, additional, Fraser, Aileen, additional, Punnette, Dwayne, additional, Lambert, Rebecca, additional, Bishop-Hurman, Charlotte, additional, Undrell, Elizabeth, additional, Belfield, Katherine, additional, Din, Said, additional, Addleton, Catherine, additional, Appleby, Marie, additional, Brown, Johanna, additional, Holding, Kathleen, additional, Fraser, Catherine, additional, Birkenshaw, Janice, additional, Williams, Jodie, additional, Maulion, Kamille, additional, Lane, Meg, additional, Kravale, Arita, additional, Smith, Claud, additional, Hooper, Patricia, additional, deCaestecker, John, additional, Watchorn, Olivia, additional, Clarke, Ellie, additional, Hayward, Chris, additional, Inniss, Susan, additional, Pritchard, Lucy, additional, Rudge, Karen, additional, Carney, Amanda, additional, Griffee, Sarah, additional, Andreyev, Jervoise, additional, Babu, Sathish, additional, Hayhurst, Caroline, additional, Lockwood, Carol, additional, Osborne, Lynn, additional, Roper, Amanda, additional, Warner, Karen, additional, Hindle, Julia, additional, Lawrence, Tara, additional, Netherton, Kimberley, additional, Watt, Caroline, additional, Szymiczek, Kinga, additional, Mehta, Shameer, additional, Bell, James, additional, Blad, William, additional, Whitley, Lisa, additional, Jastrub, Roman, additional, Durai, Dhamaraj, additional, Baker, Mark, additional, John Sivamurugan, Elizabeth, additional, Evans, Mim, additional, Cummings, Fraser, additional, Harris, Clare, additional, Jones, Amy, additional, Krauze, Liga, additional, Rahmany, Sohail, additional, Earl, Michelle, additional, Vowles, Jenny, additional, Torokwa, Audrey, additional, Petrova, Mirela, additional, Procter, Andrew, additional, Stanley, Jo, additional, Silvamoniz, Claudia, additional, Bettey, Marion, additional, Wahid, Amar, additional, Morrison, Zoe, additional, Thomas-Turner, Rhian, additional, Yendle, Louise, additional, Muller, Jennifer, additional, Mitchell, Marcus, additional, Kirkwood, John, additional, Barnes, Anna, additional, Chaudhary, Rakesh, additional, Claridge, Melanie, additional, Ellis, Chiara, additional, Kemp, Cheryl, additional, Tobi, Ogwa, additional, Milton, Jentus, additional, Johnston, Emma, additional, Oblak, Metod, additional, Winpenny, Carmen, additional, Svensson, Marie-Louise, additional, Godden, Jo, additional, Ashhar, Marium, additional, Alexander, Debbie, additional, Covil, Kate, additional, Derikx, Lauranne, additional, Siakavellas, Sryros, additional, Baxter, Helen, additional, Robertson, Scott, additional, Smith, Linda, additional, Poulose, Beena, additional, Colemam, Anne, additional, Balint, Margareta, additional, Rhys-Jones, Gareth, additional, Watters, Helen, additional, Begg, Susan, additional, Grosalcalde, Beatriz, additional, Coyle, Judy, additional, Johns, Kerrie, additional, Hughes, Rachel, additional, Phipps, Janet, additional, Taylor, Abigail, additional, MacPhee, Catherine, additional, Brooks, Suzanne, additional, John, Jolene, additional, Edwards, Michelle, additional, Smith, Katie, additional, Howard, Linda, additional, Wood, Dianne, additional, Muddu, Ajay, additional, Barman, Laura, additional, Mallinson, Janine, additional, Neale, Tania, additional, Ionita, Diana, additional, Elliot, Kerry, additional, Turnball, Alison, additional, Thomas, Iola, additional, Thomas, Alice, additional, Andrews, Kelly, additional, Sutton, Jonathon, additional, Mulvaney Jones, Caroline, additional, Roberts, Julia, additional, and Bishop, Jeannie, additional

Published
2023
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49. Biolimus-Eluting vs. Other Limus-Eluting Stents in NSTE-ACS: A Pooled Analysis of GLASSY and TWILIGHT

Author

Spirito, Alessandro, primary, Valgimigli, Marco, additional, Cao, Davide, additional, Baber, Usman, additional, Mehta, Shamir, additional, Gibson, Michael, additional, Steg, Philippe Gabriel, additional, Sharma, Samin, additional, Goel, Ridhima, additional, Huber, Kurt, additional, Kunadian, Vijay, additional, Escaned, Javier, additional, Franzone, Anna, additional, Yaling, Han, additional, Collier, Timothy, additional, Kaul, Upendra, additional, Kornowski, Ran, additional, Krucoff, Mitchell, additional, Moliterno, David, additional, Sartori, Samantha, additional, Owen, Ruth, additional, Zhang, Zhongjie, additional, Dangas, George D., additional, Kastrati, Adnan, additional, Angiolillo, Dominick Joseph, additional, Cohen, David, additional, vranckx, pascal, additional, Windecker, Stephan, additional, Pocock, Stuart, additional, and Mehran, Roxana, additional

Published
2023
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50. Polypill Strategy in Secondary Cardiovascular Prevention

Author

Castellano, Jose M, Pocock, Stuart J, Bhatt, Deepak L, Quesada, Antonio J, Owen, Ruth, Fernandez-Ortiz, Antonio, Sanchez, Pedro L, Marin Ortuño, Francisco, Vazquez Rodriguez, Jose M, Domingo-Fernández, Alexandra, Lozano, Iñigo, Roncaglioni, Maria C, Baviera, Marta, Foresta, Andreana, Ojeda-Fernandez, Luisa, Colivicchi, Furio, Di Fusco, Stefania A, Doehner, Wolfram, Meyer, Antje, Schiele, François, Ecarnot, Fiona, Linhart, Aleš, Lubanda, Jean-Claude, Barczi, Gyorgy, Merkely, Bela, Ponikowski, Piotr, Kasprzak, Marta, Fernandez Alvira, Juan M, Andres, Vicente, Bueno, Hector, Collier, Timothy, Van de Werf, Frans, Perel, Pablo, Rodriguez-Manero, Moises, Alonso Garcia, Angeles, Proietti, Marco, Schoos, Mikkel M, Simon, Tabassome, Fernandez Ferro, Jose, Lopez, Nicolas, Beghi, Ettore, Bejot, Yannick, Vivas, David, Cordero, Alberto, Ibañez, Borja, Fuster, Valentin, and SECURE Investigators

Subjects
Aspirin, Ramipril, Cardiovascular Diseases, Atorvastatin, Myocardial Infarction, Secondary Prevention, Humans, Angiotensin-Converting Enzyme Inhibitors, General Medicine, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Platelet Aggregation Inhibitors, Ischemic Stroke
Abstract

BACKGROUND: A polypill that includes key medications associated with improved outcomes (aspirin, angiotensin-converting-enzyme [ACE] inhibitor, and statin) has been proposed as a simple approach to the secondary prevention of cardiovascular death and complications after myocardial infarction. METHODS: In this phase 3, randomized, controlled clinical trial, we assigned patients with myocardial infarction within the previous 6 months to a polypill-based strategy or usual care. The polypill treatment consisted of aspirin (100 mg), ramipril (2.5, 5, or 10 mg), and atorvastatin (20 or 40 mg). The primary composite outcome was cardiovascular death, nonfatal type 1 myocardial infarction, nonfatal ischemic stroke, or urgent revascularization. The key secondary end point was a composite of cardiovascular death, nonfatal type 1 myocardial infarction, or nonfatal ischemic stroke. RESULTS: A total of 2499 patients underwent randomization and were followed for a median of 36 months. A primary-outcome event occurred in 118 of 1237 patients (9.5%) in the polypill group and in 156 of 1229 (12.7%) in the usual-care group (hazard ratio, 0.76; 95% confidence interval [CI], 0.60 to 0.96; P = 0.02). A key secondary-outcome event occurred in 101 patients (8.2%) in the polypill group and in 144 (11.7%) in the usual-care group (hazard ratio, 0.70; 95% CI, 0.54 to 0.90; P = 0.005). The results were consistent across prespecified subgroups. Medication adherence as reported by the patients was higher in the polypill group than in the usual-care group. Adverse events were similar between groups. CONCLUSIONS: Treatment with a polypill containing aspirin, ramipril, and atorvastatin within 6 months after myocardial infarction resulted in a significantly lower risk of major adverse cardiovascular events than usual care. (Funded by the European Union Horizon 2020; SECURE ClinicalTrials.gov number, NCT02596126; EudraCT number, 2015-002868-17.).

Published
2022

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