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374 results on '"Oussalah, Abderrahim"'

1. Correction: A transgenic mice model of retinopathy of cblG‑type inherited disorder of one‑carbon metabolism highlights epigenome‑wide alterations related to cone photoreceptor cells development and retinal metabolism

Author

Matmat, Karim, Conart, Jean-Baptiste, Graindorge, Paul-Henri, El Kouche, Sandra, Hassan, Ziad, Siblini, Youssef, Umoret, Rémy, Safar, Ramia, Baspinar, Okan, Robert, Aurélie, Alberto, Jean-Marc, Oussalah, Abderrahim, Hergalant, Sébastien, Coelho, David, Guéant, Jean-Louis, and Guéant-Rodriguez, Rosa-Maria

Published
2024
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2. Multiomic analysis in fibroblasts of patients with inborn errors of cobalamin metabolism reveals concordance with clinical and metabolic variability

Author

Wiedemann, Arnaud, Oussalah, Abderrahim, Guéant Rodriguez, Rosa-Maria, Jeannesson, Elise, Mertens, Marc, Rotaru, Irina, Alberto, Jean-Marc, Baspinar, Okan, Rashka, Charif, Hassan, Ziad, Siblini, Youssef, Matmat, Karim, Jeandel, Manon, Chery, Celine, Robert, Aurélie, Chevreux, Guillaume, Lignières, Laurent, Camadro, Jean-Michel, Feillet, François, Coelho, David, and Guéant, Jean-Louis

Published
2024
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3. A transgenic mice model of retinopathy of cblG-type inherited disorder of one-carbon metabolism highlights epigenome-wide alterations related to cone photoreceptor cells development and retinal metabolism

Author

Matmat, Karim, Conart, Jean-Baptiste, Graindorge, Paul-Henri, El Kouche, Sandra, Hassan, Ziad, Siblini, Youssef, Umoret, Rémy, Safar, Ramia, Baspinar, Okan, Robert, Aurélie, Alberto, Jean-Marc, Oussalah, Abderrahim, Coelho, David, Guéant, Jean-Louis, and Guéant-Rodriguez, Rosa-Maria

Published
2023
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11. Global Burden Related to Nitrous Oxide Exposure in Medical and Recreational Settings: A Systematic Review and Individual Patient Data Meta-Analysis.

Author

Oussalah, Abderrahim, Julien, Mélissa, Levy, Julien, Hajjar, Olivia, Franczak, Claire, Stephan, Charlotte, Laugel, Elodie, Wandzel, Marion, Filhine-Tresarrieu, Pierre, Green, Ralph, and Guéant, Jean-Louis

Subjects
global burden related to nitrous oxide exposure, global health, homocysteine, individual patient data meta-analysis, medical and recreational settings, methylmalonic acid, nitrous oxide-related toxicity, one-carbon metabolism, vitamin B12 deficiency, Nitrous Oxide Exposure, Individual Patient Data Meta-Analysis, Medical and Recreational Settings, N2O-related toxicity, Vitamin B12 deficiency., Nitrous Oxide Exposure, Individual Patient Data Meta-Analysis, Medical and Recreational Settings, N2O-related toxicity, Vitamin B12 deficiency., Clinical Sciences
Abstract

The risk of adverse effects of nitrous oxide (N2O) exposure is insufficiently recognized despite its widespread use. These effects are mainly reported through case reports. We conducted an individual patient data meta-analysis to assess the prevalence of clinical, laboratory, and magnetic resonance findings in association with N2O exposure in medical and recreational settings. We calculated the pooled estimates for the studied outcomes and assessed the potential bias related to population stratification using principal component analysis. Eighty-five publications met the inclusion criteria and reported on 100 patients with a median age of 27 years and 57% of recreational users. The most frequent outcomes were subacute combined degeneration (28%), myelopathy (26%), and generalized demyelinating polyneuropathy (23%). A T2 signal hyperintensity in the spinal cord was reported in 68% (57.2-78.8%) of patients. The most frequent clinical manifestations included paresthesia (80%; 72.0-88.0%), unsteady gait (58%; 48.2-67.8%), and weakness (43%; 33.1-52.9%). At least one hematological abnormality was retrieved in 71.7% (59.9-83.4%) of patients. Most patients had vitamin B12 deficiency: vitamin B12 15 µmol/L (90.3%; 79.3-100%), and methylmalonic acid >0.4 µmol/L (93.8%; 80.4-100%). Consistently, 85% of patients exhibited a possibly or probably deficient vitamin B12 status according to the cB12 scoring system. N2O can produce severe outcomes, with neurological or hematological disorders in almost all published cases. More than half of them are reported in the setting of recreational use. The N2O-related burden is dominated by vitamin B12 deficiency. This highlights the need to evaluate whether correcting B12 deficiency would prevent N2O-related toxicity, particularly in countries with a high prevalence of B12 deficiency.

Published
2019

13. Heterozygous Mutations in Both the AMN and CBS Genes: Double Haploinsufficiency as an Unusual Cause of Vitamin B12 Deficiency—A Case Report.

Author

Iversen, Per Ole, Gueant, Jean‐Louis, Oussalah, Abderrahim, Refsum, Helga, Nexo, Ebba, Tjønnfjord, Geir E., and Qvigstad, Christian

Subjects
VITAMIN B12 deficiency, VITAMIN B12, FOLIC acid, VITAMINS, HEMATOLOGY
Abstract

Vitamin B12 deficiency is usually simple to diagnose. However, our patient demonstrates that in difficult cases, the ordinary clinician may need a transdisciplinary approach. The finding of a double haploinsufficiency as a possible cause of vitamin B12 deficiency in our patient, illustrates the usefulness of performing large panel clinical exome sequencing. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Multiparametric renal function assessment in cirrhotic patients shows high prevalence of medically actionable changes in multiple modules.

Author

Belmonte, Richard, Silva‐Rodriguez, Maël, Barbé, Françoise, Bensenane, Mouni, Haghenejad, Vincent, Vrillon, Isabelle, Alla, Asma, Flahault, Adrien, Kormann, Raphael, Corbel, Alice, Aitdjafer, Zakia, Quilliot, Didier, Derain‐Dubourg, Laurence, Namour, Farès, Guéant, Jean‐Louis, Bronowicki, Jean‐Pierre, and Oussalah, Abderrahim

Subjects
GLOMERULAR filtration rate, KIDNEY physiology, CHRONIC kidney failure, SALINE waters, CONSORTIA
Abstract

Aim: Renal dysfunction is a common complication of cirrhosis, occurring either as part of multiorgan involvement in acute illness or secondary to advanced liver disease. To date, no study has comprehensively assessed multiple renal function parameters in hospitalized patients with cirrhosis through a multiparametric analysis of renal biochemistry markers. Methods: We conducted a retrospective, observational study including all consecutive patients hospitalized with cirrhosis who underwent a 43‐multiparametric renal function assessment between January 1, 2021, and June 30, 2023. Results: All patients showed at least one of the following renal abnormalities: Kidney Disease: Improving Global Outcomes stage G2 or higher, sodium and/or chloride excretion fraction <1%, electrolyte‐free water clearance <0.4 mL/min, or tubular maximum phosphate reabsorption capacity <0.8 mmol/L. The estimated glomerular filtration rate equations significantly overestimated the measured creatinine clearance with median differences of +14 mL/min/1.73 m2 (95% CI 6–29) and +9 mL/min/1.73 m2 (95% CI 2–15) for European Kidney Function Consortium equations, respectively. Notably, 54% and 39% of patients demonstrated estimated glomerular filtration rates exceeding 30% of the measured creatinine clearance when the Chronic Kidney Disease ‐ Epidemiology Collaboration and European Kidney Function Consortium formulas were employed, respectively. Substantial discrepancies in Kidney Disease: Improving Global Outcomes stage assignments were observed between the estimated glomerular filtration rate‐ and measured creatinine clearance‐based assessments. Conclusions: This study underscores the value of a multiparametric renal function assessment as a routine tool for evaluating renal function in patients with cirrhosis. A high prevalence of medically actionable renal abnormalities spanning multiple renal function modules, including alterations in glomerular function, salt and solute‐free water excretion, and proximal tubule phosphate reabsorption, has been demonstrated in hospitalized patients with cirrhosis. [ABSTRACT FROM AUTHOR]

Published
2024
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15. The EKFC equation outperforms the CKD‐EPI and CKiD equations for GFR estimation in adolescent and young adult kidney transplant patients.

Author

Grosyeux, Chloé, Alla, Asma, Barbé, Françoise, Dubourg, Laurence Derain, Chardon, Laurence, Guéant, Jean‐Louis, Frimat, Luc, Oussalah, Abderrahim, and Vrillon, Isabelle

Subjects
GLOMERULAR filtration rate, YOUNG adults, CHILD patients, ESTIMATION bias, KIDNEY transplantation
Abstract

Aim: This study evaluated the bias and accuracy of the CKD‐EPI/CKiD and EKFC equations compared with the reference exogenous tracer‐based assessment of glomerular filtration rate (GFR) in adult and pediatric patients according to their renal transplant status. Methods: We assessed the bias and P30 accuracy of the CKD‐EPI/CKiD and EKFC equations compared with iohexol‐based GFR measurement. Results: In the overall population (n = 59), the median age was 29 years (IQR, 16.0–46.0) and the median measured GFR was 73.9 mL/min/1.73m2 (IQR, 57.3–84.6). Among non‐kidney transplant patients, the median was 77.7 mL/min/1.73m2 (IQR, 59.3–86.5), while among kidney transplant patients, it was 60.5 mL/min/1.73m2 (IQR, 54.2–66.8). The bias associated with the EKFC and CKD‐EPI/CKiD equations was significantly higher among kidney transplant patients than among non‐kidney transplant patients, with a difference between medians (Hodges–Lehmann) of +10.4 mL/min/1.73m2 (95% CI, 2.2–18.9; p =.02) for the EKFC and +12.1 mL/min/1.73m2 (95% CI, 4.2–21.4; p =.006) for the CKD‐EPI/CKiD equations. In multivariable analysis, kidney transplant status emerged as an independent factor associated with a bias of >3.4 mL/min/1.73m2 (odds ratio, 7.7; 95% CI, 1.4–43.3; p =.02) for the EKFC equation and a bias of >13.4 mL/min/1.73m2 (odds ratio, 15.0; 95% CI, 2.6–85.7; p =.002) for the CKD‐EPI/CKiD equations. Conclusion: In our study, which included adolescent and young adult kidney transplant patients, both the CKD‐EPI/CKiD and EKFC equations tended to overestimate the measured glomerular filtration rate, with the EKFC equation exhibiting less bias. Renal transplant status significantly influenced the degree of estimation bias. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Common genetic variation in alcohol-related hepatocellular carcinoma: a case-control genome-wide association study

Author

Meiller, Clément, Cao, Qian, Hirsch, Théo Z., Rebouissou, Sandra, Degré, Delphine, Otero Sanchez, Lukas, Rosewick, Nicolas, Quertinmont, Eric, Desille-Dugast, Mireille, François-Vié, Muriel, Moins, Cécile, Leteurtre, Emmanuelle, Lassailly, Guillaume, Ningarhari, Massih, Boleslawski, Emmanuel, Cottet, Vanessa, Trépo, Eric, Caruso, Stefano, Yang, Jie, Imbeaud, Sandrine, Couchy, Gabrielle, Bayard, Quentin, Letouzé, Eric, Ganne-Carrié, Nathalie, Moreno, Christophe, Oussalah, Abderrahim, Féray, Cyrille, Blanc, Jean Frédéric, Clément, Bruno, Hillon, Patrick, Boursier, Jérôme, Paradis, Valérie, Calderaro, Julien, Gnemmi, Viviane, Nault, Jean-Charles, Guéant, Jean-Louis, Devière, Jacques, Archambeaud, Isabelle, Vitellius, Carole, Turlin, Bruno, Bronowicki, Jean-Pierre, Gustot, Thierry, Sutton, Angela, Ziol, Marianne, Nahon, Pierre, and Zucman-Rossi, Jessica

Published
2022
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17. Epimutations in both the TESK2 and MMACHC promoters in the Epi-cblC inherited disorder of intracellular metabolism of vitamin B12

Author

Oussalah, Abderrahim, Siblini, Youssef, Hergalant, Sébastien, Chéry, Céline, Rouyer, Pierre, Cavicchi, Catia, Guerrini, Renzo, Morange, Pierre-Emmanuel, Trégouët, David, Pupavac, Mihaela, Watkins, David, Pastinen, Tomi, Chung, Wendy K., Ficicioglu, Can, Feillet, François, Froese, D. Sean, Baumgartner, Matthias R., Benoist, Jean-François, Majewski, Jacek, Morrone, Amelia, Rosenblatt, David S., and Guéant, Jean-Louis

Published
2022
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19. Expanding the clinical spectrum of STIP1 homology and U-box containing protein 1-associated ataxia

Author

Ravel, Jean-Marie, Benkirane, Mehdi, Calmels, Nadège, Marelli, Cecilia, Ory-Magne, Fabienne, Ewenczyk, Claire, Halleb, Yosra, Tison, François, Lecocq, Claire, Pische, Guillaume, Casenave, Philippe, Chaussenot, Annabelle, Frismand, Solène, Tyvaert, Louise, Larrieu, Lise, Pointaux, Morgane, Drouot, Nathalie, Bossenmeyer-Pourié, Carine, Oussalah, Abderrahim, Guéant, Jean-Louis, Leheup, Bruno, Bonnet, Céline, Anheim, Mathieu, Tranchant, Christine, Lambert, Laëtitia, Chelly, Jamel, Koenig, Michel, and Renaud, Mathilde

Published
2021
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20. The spectrum of biochemical alterations associated with organ dysfunction and inflammatory status and their association with disease outcomes in severe COVID-19: A longitudinal cohort and time-series design study

Author

Oussalah, Abderrahim, Gleye, Stanislas, Urmes, Isabelle Clerc, Laugel, Elodie, Barbé, Françoise, Orlowski, Sophie, Malaplate, Catherine, Aimone-Gastin, Isabelle, Caillierez, Beatrice Maatem, Merten, Marc, Jeannesson, Elise, Kormann, Raphaël, Olivier, Jean-Luc, Rodriguez-Guéant, Rosa-Maria, Namour, Farès, Bevilacqua, Sybille, Thilly, Nathalie, Losser, Marie-Reine, Kimmoun, Antoine, Frimat, Luc, Levy, Bruno, Gibot, Sébastien, Schvoerer, Evelyne, and Guéant, Jean-Louis

Published
2020
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24. PRDX1 gene-related epi-cblC disease is a common type of inborn error of cobalamin metabolism with mono- or bi-allelic MMACHC epimutations

Author

Cavicchi, Catia, Oussalah, Abderrahim, Falliano, Silvia, Ferri, Lorenzo, Gozzini, Alessia, Gasperini, Serena, Motta, Serena, Rigoldi, Miriam, Parenti, Giancarlo, Tummolo, Albina, Meli, Concetta, Menni, Francesca, Furlan, Francesca, Daniotti, Marta, Malvagia, Sabrina, la Marca, Giancarlo, Chery, Céline, Morange, Pierre-Emmanuel, Tregouet, David, Donati, Maria Alice, Guerrini, Renzo, Guéant, Jean-Louis, and Morrone, Amelia

Published
2021
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27. Plasma mSEPT9: A Novel Circulating Cell-free DNA-Based Epigenetic Biomarker to Diagnose Hepatocellular Carcinoma

Author

Oussalah, Abderrahim, Rischer, Susann, Bensenane, Mouni, Conroy, Guillaume, Filhine-Tresarrieu, Pierre, Debard, Renée, Forest-Tramoy, Denise, Josse, Thomas, Reinicke, Dana, Garcia, Matthieu, Luc, Amandine, Baumann, Cédric, Ayav, Ahmet, Laurent, Valérie, Hollenbach, Marcus, Ripoll, Cristina, Guéant-Rodriguez, Rosa-Maria, Namour, Fares, Zipprich, Alexander, Fleischhacker, Michael, Bronowicki, Jean-Pierre, and Guéant, Jean-Louis

Published
2018
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30. MicroRNAs miR-16 and miR-519 control meningioma cell proliferation via overlapping transcriptomic programs shared with the RNA-binding protein HuR

Author

Hergalant, Sébastien, primary, Casse, Jean-Matthieu, additional, Oussalah, Abderrahim, additional, Houlgatte, Rémi, additional, Helle, Déborah, additional, Rech, Fabien, additional, Vallar, Laurent, additional, Guéant, Jean-Louis, additional, Vignaud, Jean-Michel, additional, Battaglia-Hsu, Shyue-Fang, additional, and Gauchotte, Guillaume, additional

Published
2023
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32. HLA-DRA variants predict penicillin allergy in genome-wide fine-mapping genotyping

Author

Guéant, Jean-Louis, Romano, Antonino, Cornejo-Garcia, Jose-Antonio, Oussalah, Abderrahim, Chery, Celine, Blanca-López, Natalia, Guéant-Rodriguez, Rosa-Maria, Gaeta, Francesco, Rouyer, Pierre, Josse, Thomas, Canto, Gabriella, Carmona, F. David, Bossini-Castillo, Lara, Martin, Javier, Laguna, Jose-Julio, Fernandez, Javier, Feo, Francisco, Ostrov, David A., Plasencia, Pablo C., Mayorga, Cristobalina, Torres, Maria-Jose, and Blanca, Miguel

Published
2015
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33. Additional file 1 of Usefulness of procalcitonin at admission as a risk-stratifying biomarker for 50-day in-hospital mortality among patients with community-acquired bloodstream infection: an observational cohort study

Author

Oussalah, Abderrahim, Callet, Jonas, Manteaux, Anne-Elisabeth, Thilly, Nathalie, Jay, Nicolas, Guéant, Jean-Louis, and Lozniewski, Alain

Abstract

Additional file 1: Supplemental methods. Supplemental Table S1. Probit regression analysis for the propensity score predicted by the logistic regression model as the dose variable and the risk of 50-day in-hospital mortality as the response variable. Supplemental Table 2. Association between plasma procalcitonin level at admission and all-cause 50-day mortality in multivariable logistic regression analysis. Supplemental Table S3. Kaplan-Meier analysis reporting the probability of survival without in-hospital mortality according to the ROC-defined plasma procalcitonin threshold (> 4.24 ng/mL) at baseline. Supplemental Table S4. Hazard ratios and 95% confidence interval for the pairwise comparison of survival probabilities without in-hospital mortality according to the ROC-defined plasma procalcitonin threshold (> 4.24 ng/mL) at baseline. Supplemental Table S5. Association between plasma procalcitonin level at admission and all-cause in-hospital mortality in multivariable Cox proportional-hazards regression. Supplemental Table S6. Distribution of procalcitonin values according to procalcitonin quartiles. Supplemental Table S7. Kaplan-Meier analysis reporting the probability of survival without in-hospital mortality in the 452 studied patients according to baseline plasma procalcitonin quartiles. Supplemental Table S8. Hazard ratios and 95% confidence interval for the pairwise comparison of survival probabilities without in-hospital mortality according to baseline procalcitonin quartiles. Supplemental Figure S1. Flow diagram of patient selection. Supplemental Figure S2. (A) Kaplan-Meier analysis reporting the probability of survival without in-hospital mortality according to the ROC-defined plasma troponin threshold (> 0.05 ng/mL) at baseline; (B) Kaplan-Meier analysis reporting the probability of survival without in-hospital mortality according to the ROC-defined plasma lactates threshold (> 4.24 ng/mL) at baseline. Supplemental Figure S3. Probit sigmoid dose-response curve showing the propensity score predicted by the logistic regression model as the dose variable and the risk of 50-day in-hospital mortality as the response variable. The red line shows the probability and corresponding dose. The dashed curves represent the 95% confidence interval for the respective dose. The dose and 95% confidence interval corresponding with a particular probability are taken from a horizontal line at that probability level. Supplemental Figure S4. (A) Kaplan-Meier ainalysis reporting the probability of survival without in-hospital mortality in the 452 studied patients. The dashed lines represent the 95% confidence interval of the survival probabilities; (B) Kaplan-Meier analysis reporting the probability of survival without in-hospital mortality according to the ROC-defined plasma procalcitonin threshold (> 4.24 ng/mL) at baseline.

Published
2023
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38. Ascitic fluid mid-regional-pro-adrenomedullin (MR-pro-ADM): a novel rapid-assay sepsis biomarker to diagnose spontaneous bacterial peritonitis in cirrhotic patients

Author

Oussalah, Abderrahim, primary, Lagneaux, Anne-Sophie, additional, Alix, Tom, additional, Filhine-Tresarrieu, Pierre, additional, Callet, Jonas, additional, Ferrand, Janina, additional, Jung, Jean, additional, Broseus, Julien, additional, Salignac, Sylvain, additional, Luc, Amandine, additional, Baumann, Cédric, additional, Schuetz, Philipp, additional, Lozniewski, Alain, additional, Peoch, Katell, additional, Puy, Hervé, additional, Guéant, Jean-Louis, additional, and Bronowicki, Jean-Pierre, additional

Published
2022
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40. Common genetic variation in alcohol-related hepatocellular carcinoma: a case-control genome-wide association study.

Author

Trepo, Eric, Caruso, Stefano, Yang, Jie, Imbeaud, Sandrine, Couchy, Gabrielle, Bayard, Quentin, Letouzé, Eric, Ganne-Carrié, Nathalie, Moreno, Christophe, Oussalah, Abderrahim, Féray, Cyrille, Blanc, Jean Frédéric, Clément, Bruno, Hillon, Patrick, Boursier, Jérôme, Paradis, Valérie, Calderaro, Julien, Gnemmi, Viviane, Nault, Jean Charles, Guéant, Jean-Louis, Devière, Jacques, Archambeaud, Isabelle, Vitellius, Carole, Turlin, Bruno, Bronowicki, Jean-Pierre, Gustot, Thierry, Sutton, Angela, GENTHEP Consortium, Ziol, Marianne, Nahon, Pierre, Zucman-Rossi, Jessica, Trepo, Eric, Caruso, Stefano, Yang, Jie, Imbeaud, Sandrine, Couchy, Gabrielle, Bayard, Quentin, Letouzé, Eric, Ganne-Carrié, Nathalie, Moreno, Christophe, Oussalah, Abderrahim, Féray, Cyrille, Blanc, Jean Frédéric, Clément, Bruno, Hillon, Patrick, Boursier, Jérôme, Paradis, Valérie, Calderaro, Julien, Gnemmi, Viviane, Nault, Jean Charles, Guéant, Jean-Louis, Devière, Jacques, Archambeaud, Isabelle, Vitellius, Carole, Turlin, Bruno, Bronowicki, Jean-Pierre, Gustot, Thierry, Sutton, Angela, GENTHEP Consortium, Ziol, Marianne, Nahon, Pierre, and Zucman-Rossi, Jessica

Abstract

Hepatocellular carcinoma is a frequent consequence of alcohol-related liver disease, with variable incidence among heavy drinkers. We did a genome-wide association study (GWAS) to identify common genetic variants for alcohol-related hepatocellular carcinoma., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2022

42. Helicobacter pylori serologic status has no influence on the association between fucosyltransferase 2 polymorphism (FUT2 461 G→A) and vitamin B-12 in Europe and West Africa

Author

Oussalah, Abderrahim, Besseau, Cyril, Chery, Céline, Jeannesson, Elise, Guéant-Rodriguez, Rosa-Maria, Anello, Guido, Bosco, Paolo, Elia, Maurizzio, Romano, Antonino, Bronowicki, Jean-Pierre, Gerard, Philippe, Paoli, Justine, Avogbe, Patrice Hodonou, Chabi, Nicodème, Sanni, Ambaliou, Amouzou, Emile, Peyrin-Biroulet, Laurent, and Guéant, Jean-Louis

Published
2012
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43. Additional file 2 of Epimutations in both the TESK2 and MMACHC promoters in the Epi-cblC inherited disorder of intracellular metabolism of vitamin B12

Author

Oussalah, Abderrahim, Siblini, Youssef, Hergalant, Sébastien, Chéry, Céline, Rouyer, Pierre, Cavicchi, Catia, Guerrini, Renzo, Morange, Pierre-Emmanuel, Trégouët, David, Pupavac, Mihaela, Watkins, David, Pastinen, Tomi, Chung, Wendy K., Ficicioglu, Can, Feillet, François, Froese, D. Sean, Baumgartner, Matthias R., Benoist, Jean-François, Majewski, Jacek, Morrone, Amelia, Rosenblatt, David S., and Guéant, Jean-Louis

Abstract

Additional file 2. Supplemental Figure S2. (A) 2-D plot using the two top eigenvectors (PC1, PC3) derived from the primary component analysis on the genome-wide methylome landscape of the studied patients and controls. (B) 2-D plot using the PC1 and PC2 eigenvectors derived from the primary component analysis on the methylome landscape of chromosome 1 of the studied patients and controls.

Published
2022
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44. Additional file 3 of Epimutations in both the TESK2 and MMACHC promoters in the Epi-cblC inherited disorder of intracellular metabolism of vitamin B12

Author

Oussalah, Abderrahim, Siblini, Youssef, Hergalant, Sébastien, Chéry, Céline, Rouyer, Pierre, Cavicchi, Catia, Guerrini, Renzo, Morange, Pierre-Emmanuel, Trégouët, David, Pupavac, Mihaela, Watkins, David, Pastinen, Tomi, Chung, Wendy K., Ficicioglu, Can, Feillet, François, Froese, D. Sean, Baumgartner, Matthias R., Benoist, Jean-François, Majewski, Jacek, Morrone, Amelia, Rosenblatt, David S., and Guéant, Jean-Louis

Abstract

Additional file 3. Supplemental Table S1. Forward and reverse primers for reverse transcription-quantitative polymerase chain reaction (RT-qPCR) of MMACHC, TESK2 transcripts and PRDX1 aberrant transcript.

Published
2022
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46. Common genetic variation in alcohol-related hepatocellular carcinoma: a case-control genome-wide association study

Author

Trépo, Eric, primary, Caruso, Stefano, additional, Yang, Jie, additional, Imbeaud, Sandrine, additional, Couchy, Gabrielle, additional, Bayard, Quentin, additional, Letouzé, Eric, additional, Ganne-Carrié, Nathalie, additional, Moreno, Christophe, additional, Oussalah, Abderrahim, additional, Féray, Cyrille, additional, Blanc, Jean Frédéric, additional, Clément, Bruno, additional, Hillon, Patrick, additional, Boursier, Jérôme, additional, Paradis, Valérie, additional, Calderaro, Julien, additional, Gnemmi, Viviane, additional, Nault, Jean-Charles, additional, Guéant, Jean-Louis, additional, Devière, Jacques, additional, Archambeaud, Isabelle, additional, Vitellius, Carole, additional, Turlin, Bruno, additional, Bronowicki, Jean-Pierre, additional, Gustot, Thierry, additional, Sutton, Angela, additional, Ziol, Marianne, additional, Nahon, Pierre, additional, Zucman-Rossi, Jessica, additional, Meiller, Clément, additional, Cao, Qian, additional, Hirsch, Théo Z., additional, Rebouissou, Sandra, additional, Degré, Delphine, additional, Otero Sanchez, Lukas, additional, Rosewick, Nicolas, additional, Quertinmont, Eric, additional, Desille-Dugast, Mireille, additional, François-Vié, Muriel, additional, Moins, Cécile, additional, Leteurtre, Emmanuelle, additional, Lassailly, Guillaume, additional, Ningarhari, Massih, additional, Boleslawski, Emmanuel, additional, and Cottet, Vanessa, additional

Published
2022
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48. Next‐generation sequencing and genotype association studies reveal the association of HLA‐DRB3*02:02 with delayed hypersensitivity to penicillins

Author

Romano, Antonino, primary, Oussalah, Abderrahim, additional, Chery, Celine, additional, Guéant‐Rodriguez, Rosa‐Maria, additional, Gaeta, Francesco, additional, Cornejo‐Garcia, Jose‐Antonio, additional, Rouyer, Pierre, additional, Josse, Thomas, additional, Mayorga, Cristobalina, additional, Torres, Maria‐Jose, additional, and Guéant, Jean‐Louis, additional

Published
2021
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49. Low-frequency Coding Variants Associated With Body Mass Index Affect the Success of Bariatric Surgery

Author

Antoine, Darlène, primary, Guéant-Rodriguez, Rosa-Maria, additional, Chèvre, Jean-Claude, additional, Hergalant, Sébastien, additional, Sharma, Tanmay, additional, Li, Zhen, additional, Rouyer, Pierre, additional, Chery, Céline, additional, Halvick, Sarah, additional, Bui, Catherine, additional, Oussalah, Abderrahim, additional, Ziegler, Olivier, additional, Quilliot, Didier, additional, Brunaud, Laurent, additional, Guéant, Jean-Louis, additional, and Meyre, David, additional

Published
2021
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