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A hydrochemical characterization of the waters of the study region (North-East Algeria) was carried out following samples taken at 36 thermal springs and their effluents during May 2022. The analysis of the waters allowed to establish the chemical facies and their classification according to the Stuyfzand's method and to deduce the aptitude of these waters for irrigation and the risks of salinity. The results revealed physico-chemical characteristics, relatively, variable. Q-mode cluster analysis was applied to the thermal water, generated four (4) groups clusters. Group1 represent a group of waters with low salinity dominatedby Na-HCO3; Stuyfzand's classification indicated that the waters are fresh-brackish with moderate to moderately high alkalinity. Taking into account the classification of Richards; we were able to identify the presence of the C3S1 class for the majority of the stations. The C3S1 class designates waters that can be used without any particular control for the irrigation of crops that are moderately tolerant to salts. These waters have average EC values of 3616.3µS/cm allowing their use in a less restrictive way for irrigation. Potential environmental effluents from the thermal spas could pollute both irrigation and drinking water, which represents a danger to the health of the region's inhabitants.

(IF N/A [2018]; Q3); International audience; In this study, the analytical data set of 26 groundwater samples from the alluvial aquifer of Boumerzoug-El khroub valley has been processed simultaneously with Multivariate analysis, geostatistical modeling, WQI, and geochemical modeling. Cluster analysis identified three main water types based on the major ion contents, where mineralization increased from group 1 to group 3. These groups were confirmed by FA/PCA, which demonstrated that groundwater quality is influenced by geochemical processes (water–rock interaction) and human practice (irrigation). The exponential semivariogram model fitted best for all hydrochemical parameters values and WQI. Groundwater chemistry has a strong spatial structure for Mg, Na, Cl, and NO3, and a moderate spatial structure for EC, Ca, K, HCO3, and SO4. Water quality maps generated using ordinary Kriging are consistent with the HCA and PCA results. All water groups are supersaturated with respect to carbonate minerals, and dissolution of kaolinite and Ca-smectite is one of the processes responsible for hydrochemical evolution in the area.

A study of thirteen geothermal springs located in the geothermal field of Guelma, northeastern Algeria, was conducted. Samples were collected during the period between January 2014 and February 2016. Geochemical processes responsible for the chemical composition of thermal and mineralized water were evaluated. The hydrochemical analysis shows that the thermal waters are characterized by the presence of two different chemical facies, the first type SO4–Ca in the east, west and south of Guelma, the second type HCO3–Ca in the south. This analysis also attributed to sodium, chlorides, and sulfates to an evaporitic terrigenous origin by the molar ratio Sr2+/Ca2+. The thermal spring waters from Guelma geothermal system have a meteoric origin, and all samples are immature with strong mixing between hot and shallow waters with 19–38.5% rate of mixing. The silica geothermometer shows that these thermal waters have a temperature varying from 84 to 122 °C and that the water came from a depth of 2100–3000 m through a fault system that limits the pull-apart basin of Guelma. Potential environmental effluent from thermal spas could pollute in both the irrigation and drinking waters, and which imposes danger on the health of the inhabitants of the region.

We previously demonstrated that natural killer (NK) cells generated after haploidentical stem-cell transplantation (SCT) are blocked at an immature state characterized by phenotypic features and impaired functioning, a blockage that may affect transplantation outcome (Nguyen et al. Blood 2005). Hypothesizing that the absence of mature donor T cells in the graft may affect NK cell differentiation and function, we examined NK cells from 21 patients who received haploidentical SCT from relatives for advanced malignant hematopoietic disease and underwent either partial (pTCD) (CD3+ in the graft >1x105/Kg, mean: 6.9x105/Kg; n=11) or extensive (e-TCD) (CD3+ in the graft