374 results on '"Ou, Tian-miao"'
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2. Design, synthesis, and evaluation of novel quindoline derivatives with fork-shaped side chains as RNA G-quadruplex stabilizers for repressing oncogene NRAS translation
3. Scaffolds in cytotoxic drugs and novel antitumor molecules interacting with nucleic acids
4. List of contributors
5. Design, synthesis, and evaluation of 9-(pyrimidin-2-yl)-9H-carbazole derivatives disrupting mitochondrial homeostasis in human lung adenocarcinoma
6. Discovery of a promising agent IQZ23 for the treatment of obesity and related metabolic disorders
7. Probes and drugs that interfere with protein translation via targeting to the RNAs or RNA-protein interactions
8. Interaction of Quindoline derivative with telomeric repeat–containing RNA induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2
9. Curcusone C induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2
10. Synthesis and evaluation of 7-substituted-5,6-dihydrobenzo[c]acridine derivatives as new c-KIT promoter G-quadruplex binding ligands
11. Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment
12. Design, synthesis and biological evaluation of 4-anilinoquinazoline derivatives as new c-myc G-quadruplex ligands
13. Accurate high-throughput identification of parallel G-quadruplex topology by a new tetraaryl-substituted imidazole
14. Blocking the binding of WT1 to bcl-2 promoter by G-quadruplex ligand SYUIQ-FM05
15. Complicated behavior of G-quadruplexes and evaluating G-quadruplexes' ligands in various systems mimicking cellular circumstance
16. Author Correction: Regio- and stereoselective synthesis of tetra- and triarylethenes by N-methylimidodiacetyl boron-directed palladium-catalysed three-component coupling
17. Discovery of natural alkaloid bouchardatine as a novel inhibitor of adipogenesis/lipogenesis in 3T3-L1 adipocytes
18. Design, synthesis and biological evaluation of novel 7-alkylamino substituted benzo[a]phenazin derivatives as dual topoisomerase I/II inhibitors
19. Design, synthesis, and biological evaluation of 2-arylethenylquinoline derivatives as multifunctional agents for the treatment of Alzheimer's disease
20. Synthesis of α-Boryl Ketones via Hydration or Oxidation of B(MIDA)-Decorated Alkynes
21. Mechanistic studies on the anticancer activity of 2,4-disubstituted quinazoline derivative
22. Stabilization of VEGF G-quadruplex and inhibition of angiogenesis by quindoline derivatives
23. Synthesis and evaluation of new BODIPY-benzofuroquinoline conjugates for sensitive and selective DNA detection
24. G-quadruplex-mediated regulation of telomere binding protein POT1 gene expression
25. Cellular nucleic acid binding protein suppresses tumor cell metastasis and induces tumor cell death by downregulating heterogeneous ribonucleoprotein K in fibrosarcoma cells
26. Chapter 5 - Scaffolds in cytotoxic drugs and novel antitumor molecules interacting with nucleic acids
27. Regio- and stereoselective synthesis of tetra- and triarylethenes by N-methylimidodiacetyl boron-directed palladium-catalysed three-component coupling
28. The role of positive charges on G-quadruplex binding small molecules: Learning from bisaryldiketene derivatives
29. Mechanistic studies for the role of cellular nucleic-acid-binding protein (CNBP) in regulation of c-myc transcription
30. Design, synthesis and biological evaluation of novel mansonone E derivatives prepared via CuAAC click chemistry as topoisomerase II inhibitors
31. Facile syntheses of disubstituted bis(vinylquinolinium)benzene derivatives as G-quadruplex DNA binders
32. New quinazoline derivatives for telomeric G-quadruplex DNA: Effects of an added phenyl group on quadruplex binding ability
33. 12-N-Methylated 5,6-dihydrobenzo[c]acridine derivatives: A new class of highly selective ligands for c-myc G-quadruplex DNA
34. Disubstituted 1,8-dipyrazolcarbazole derivatives as a new type of c-myc G-quadruplex binding ligands
35. Design, synthesis and evaluation of isaindigotone derivatives as dual inhibitors for acetylcholinesterase and amyloid beta aggregation
36. Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA
37. Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c-MYC Transcription Repressors Targeting the Promoter G-Quadruplex
38. Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer
39. Design, synthesis, and biological evaluation of curcumin analogues as multifunctional agents for the treatment of Alzheimer’s disease
40. Syntheses and characterization of nimesulide derivatives for dual enzyme inhibitors of both cyclooxygenase-1/2 and 5-lipoxygenase
41. Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation
42. Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors
43. Syntheses and characterization of novel oxoisoaporphine derivatives as dual inhibitors for cholinesterases and amyloid beta aggregation
44. A Novel Strategy for Regulating mRNA’s Degradation via Interfering the AUF1’s Binding to mRNA
45. Discovery of Clinically Used Octenidine as NRAS Repressor That Effectively Inhibits NRAS-Mutant Melanoma.
46. Bisaryldiketene derivatives: A new class of selective ligands for c-myc G-quadruplex DNA
47. Synthesis and evaluation of graveoline and graveolinine derivatives with potent anti-angiogenesis activities
48. Synthesis and evaluation of novel rutaecarpine derivatives and related alkaloids derivatives as selective acetylcholinesterase inhibitors
49. Rational design of small-molecules to recognize G-quadruplexes of c-MYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast cancer
50. Chemical intervention of the NM23-H2 transcriptional programme on c-MYC via a novel small molecule
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