Search

Your search keyword '"Ou, Shijie"' showing total 2 results
Start Over Author "Ou, Shijie"
2 results on '"Ou, Shijie"'

2. Characterization of a Novel Tn7-like Transposon Carrying blaDHA-1 in Providencia stuartii MF1 Isolated from Swine Wastewater.

Author

Ou S, Tian X, Zhang Z, Zhu L, Wang R, Cao G, Fu J, and Zhang P

Subjects
Animals, Swine, Anti-Bacterial Agents pharmacology, Genome, Bacterial, beta-Lactamases genetics, Plasmids genetics, Whole Genome Sequencing, Microbial Sensitivity Tests, Bacterial Proteins genetics, Providencia genetics, Providencia isolation & purification, Providencia drug effects, DNA Transposable Elements, Wastewater microbiology, Drug Resistance, Multiple, Bacterial genetics
Abstract

Providencia stuartii is an emerging pathogen that causes nosocomial infections. In this study, a multidrug-resistant strain P. stuartii MF1 was isolated from swine wastewater. Comprehensive analysis of whole genome sequencing revealed that dozens of antibiotic resistance genes were found in MF1. A novel transposon Tn6450M which has high sequence identity to Tn6450 and the plasmid-borne Tn6765 from Proteus mirabilis was identified in the genome of MF1. Tn6450M was determined to be stably inserted into a new attTn7 site in the P. stuartii MF1 genome and contains the third-generation cephalosporins resistance-associated genes blaDHA-1. Intergeneric transmission of Tn6450 variants poses risks for the spread of antibiotic resistance genes., Competing Interests: Declarations. Conflict of interest: The authors declare that there is no conflict of interest regarding the publication of this article., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results