128 results on '"Ottinger, Elizabeth A."'
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2. Quantifying electric vehicle mileage in the United States
3. Stabilized trimeric peptide immunogens of the complete HIV-1 gp41 N-heptad repeat and their use as HIV-1 vaccine candidates.
4. In vitro and in vivo translational models for rare liver diseases
5. Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1–2 trial
6. Locating Emergency Response Facilities in the Metrorail System: A Decision Support Tool
7. Crystal Structure of the Pleckstrin Homology-Phosphotyrosine Binding (PH-PTB) Targeting Region of Insulin Receptor Substrate 1
8. Successfully Navigating FDA Orphan Drug and Rare Pediatric Disease Designations for AAV9-hPCCA Gene Therapy: The NIH Pave-GT Experience
9. Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses
10. Successfully Navigating Food and Drug Administration Orphan Drug and Rare Pediatric Disease Designations for AAV9-hPCCA Gene Therapy: The National Institutes of Health Platform Vector Gene Therapy Experience.
11. Vaccination with peptide mimetics of the gp41 prehairpin fusion intermediate yields neutralizing antisera against HIV-1 isolates
12. Disease models for the development of therapies for lysosomal storage diseases
13. Cholesterol homeostatic responses provide biomarkers for monitoring treatment for the neurodegenerative disease Niemann–Pick C1 (NPC1)
14. Immunogenicity in mice and non-human primates of the Group A Streptococcal J8 peptide vaccine candidate conjugated to CRM197
15. Design and synthesis of inhibitors of the protein tyrosine phosphatase, SHP-2
16. Engineering, Generation and Preliminary Characterization of a Humanized Porcine Sickle Cell Disease Animal Model
17. P55 - Characterization of in vivo disposition of CTI-1601: A mitochondria targeted therapy for friedreich’s ataxia
18. Phosphocyclocreatine is the dominant form of cyclocreatine in control and creatine transporter deficiency patient fibroblasts
19. Detection and minimization of H-phosphonate side reaction during phosphopeptide synthesis by a post-assembly global phosphorylation strategy
20. Synthesis of phosphotyrosine-containing peptides and their use as substrates for protein tyrosine phosphatase
21. Additional file 1 of Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses
22. Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene
23. Solid-phase synthesis of phosphorylated peptides by phosphoramidite chemistry
24. In Vivo Efficacy of VT-1129 against Experimental Cryptococcal Meningitis with the Use of a Loading Dose-Maintenance Dose Administration Strategy
25. A novel cell immunoassay to measure survival of motor neurons protein in blood cells
26. The Platform Vector Gene Therapies Project: Increasing the Efficiency of Adeno-Associated Virus Gene Therapy Clinical Trial Startup.
27. The Fungal Cyp51 Inhibitor VT-1129 Is Efficacious in an Experimental Model of Cryptococcal Meningitis
28. Specific redistribution of cell-penetrating peptides from endosomes to the cytoplasm and nucleus upon laser illumination
29. Fostering collaborative research for rare genetic disease: the example of niemann-pick type C disease
30. Collaborative Development of 2-Hydroxypropyl-β-Cyclodextrin for the Treatment of Niemann-Pick Type C1 Disease
31. The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii
32. Phase 1/2 evaluation of intrathecal 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick disease type C1
33. A validated LC-MS/MS assay for quantification of 24(S)-hydroxycholesterol in plasma and cerebrospinal fluid
34. Fostering collaborative research for rare genetic disease: the example of niemannpick type C disease.
35. Design and synthesis of inhibitors of the protein tyrosine phosphatase, SHP-2
36. Development and validation of sensitive LC-MS/MS assays for quantification of HP-#x03B2;-CD in human plasma and CSF
37. Collaborative Development of 2-Hydroxypropyl-β-Cyclodextrin for the Treatment of Niemann-Pick Type C1 Disease
38. Sporozoite neutralizing antibodies elicited in mice and rhesus macaques immunized with a Plasmodium falciparum repeat peptide conjugated to meningococcal outer membrane protein complex
39. Immunogenicity of a Group A Streptococcal peptide vaccine conjugated to CRM197 (53.12)
40. Small Molecule Mimetics of an HIV-1 gp41 Fusion Intermediate as Vaccine Leads
41. In vitro association of the phosphatidylinositol 3-kinase regulatory subunit (p85) with the human insulin receptor
42. Inactivation of the SMN Complex by Oxidative Stress
43. A novel cell immunoassay to measure survival of motor neurons protein in blood cells
44. Effects of cargo molecules on the cellular uptake of arginine-rich cell-penetrating peptides
45. The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In VitroActivity against Cryptococcus neoformansand Cryptococcus gattii
46. Modular Folding and Evidence for Phosphorylation-induced Stabilization of an hsp90-dependent Kinase
47. Tandem SH2 Domains Confer High Specificity in Tyrosine Kinase Signaling
48. Human GRB-IRβ/GRB10
49. PTB Domains of IRS-1 and Shc Have Distinct but Overlapping Binding Specificities
50. Specificity of the PTB Domain of Shc for β Turn-forming Pentapeptide Motifs Amino-terminal to Phosphotyrosine
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