344 results on '"Ostacolo, Carmine"'
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2. Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization
3. In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel
4. New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models
5. Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification
6. Voltage-Gated K + Channel Modulation by Marine Toxins: Pharmacological Innovations and Therapeutic Opportunities.
7. In Silico Methods for the Discovery of Kv7.2/7.3 Channels Modulators: A Comprehensive Review.
8. Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization
9. KCNT1 Channel Blockers: A Medicinal Chemistry Perspective.
10. Therapeutic potential of TRPM8 antagonists in prostate cancer
11. Immunomodulatory activity of Humulus lupulus bitter acids fraction: Enhancement of natural killer cells function by NKp44 activating receptor stimulation
12. Intraocular pressure reduction with once-a-day application of a new prostaglandin eye drop: a pilot placebo-controlled study in 12 patients
13. Identification of an indol-based multi-target kinase inhibitor through phenotype screening and target fishing using inverse virtual screening approach
14. A Combination of Polymethoxyflavones from Citrus sinensis and Prenylflavonoids from Humulus lupulus Counteracts IL-1β-Induced Differentiated Caco-2 Cells Dysfunction via a Modulation of NF-κB/Nrf2 Activation
15. Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis
16. Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening
17. Topography and Pachymetry Guided, Rapid Epi-on Corneal Cross-Linking for Keratoconus: 7-year Study Results
18. Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor
19. Antioxidant peptides released from gastrointestinal digestion of “Stracchino” soft cheese: Characterization, in vitro intestinal protection and bioavailability
20. Novel Potent Decameric Peptide of Spirulina platensis Reduces Blood Pressure Levels Through a PI3K/AKT/eNOS-Dependent Mechanism
21. Peptidomimetics as Potentdual SARS-CoV-2 Cathepsin-L and Main Protease Inhibitors: In Silico Design, Synthesis and Pharmacological Characterization
22. Nanoparticles prolong N-palmitoylethanolamide anti-inflammatory and analgesic effects in vivo
23. Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis
24. Corneal Cross-Linking: The Science Beyond the Myths and Misconceptions
25. Dihydrithieno[2,3-b]naphto-4,9-dione analogues as anticancer agents: Synthesis and in cell pharmacological studies
26. In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents
27. New Frontiers on ER Stress Modulation: Are TRP Channels the Leading Actors?
28. 202 SPIRULINA, GANODERMA LUCIDUM AND MORINGA IMPROVES CARDIAC FUNCTION AND REDUCES CARDIOTOXIC BIOMARKERS IN PRECLINICAL MODELS OF SHORT-TERM DOXORUBICIN MEDIATED CARDIOTOXICITY
29. Combination of Spirulina platensis, Ganoderma lucidum and Moringa oleifera Improves Cardiac Functions and Reduces Pro-Inflammatory Biomarkers in Preclinical Models of Short-Term Doxorubicin-Mediated Cardiotoxicity: New Frontiers in Cardioncology?
30. Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization
31. Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity
32. Synthesis and biological evaluation of imidazo[1,2-a]pyrimidines and imidazo[1,2-a]pyridines as new inhibitors of the Wnt/β-catenin signaling
33. Reply
34. Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists
35. Detailed peptide profiling of “Scotta”: from a dairy waste to a source of potential health-promoting compounds
36. A nutraceutical combination of spirulina, reishi and moringa exerts significant cytoprotective effects againts doxorubicin and trastuzumab cardiotoxicity.
37. In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents.
38. New Frontiers on ER Stress Modulation: Are TRP Channels the Leading Actors?
39. In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening
40. N-4 Alkyl Cytosine Derivatives Synthesis: A New Approach
41. New TRPM8 Blockers Exert Anticancer Activity Over Castration-Resistant Prostate Cancer Models
42. Nobiletin and xanthohumol sensitize colorectal cancer stem cells to standard chemotherapy
43. l-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells
44. Nobiletin and Xanthohumol Sensitize Colorectal Cancer Stem Cells to Standard Chemotherapy
45. Lipid Nanoparticles Traverse Non-Corneal Path to Reach the Posterior Eye Segment: In Vivo Evidence
46. Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitroand In VivoAnti-Inflammatory Characterization
47. A Novel Vasoactive Peptide “PG1” from Buffalo Ice-Cream Protects from Angiotensin-Evoked High Blood Pressure
48. Citrus sinensis and Vitis vinifera Protect Cardiomyocytes from Doxorubicin-Induced Oxidative Stress: Evaluation of Onconutraceutical Potential of Vegetable Smoothies
49. Topography and Pachymetry Guided, Rapid Epi-on Corneal Cross-Linking for Keratoconus
50. Enhancement of corneal permeation of riboflavin-5′-phosphate through vitamin E TPGS: A promising approach in corneal trans-epithelial cross linking treatment
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