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321 results on '"Osoba, David"'

6. The EORTC Core Quality-of-Life Questionnaire: Interim Results of an International Field Study *

Author

Aaronson, Neil K., primary, Ahmedzai, Sam, additional, Bullinger, Monika, additional, Crabeels, Dirk, additional, Estapè, Jorge, additional, Filiberti, Antonio, additional, Flechtner, Henning, additional, Frick, Ulrich, additional, Hürny, Christoph, additional, Kaasa, Stein, additional, Klee, Marianne, additional, Mastilica, Miroslav, additional, Osoba, David, additional, Pfausler, Bettina, additional, Razavi, Darius, additional, Rofe, Peter B. C., additional, Schraub, Simon, additional, and Sullivan, Marianne, additional

Published
2021
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9. Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma

Author

Perry, James R., Laperriere, Normand, O’Callaghan, Christopher J., Brandes, Alba A., Menten, Johan, Phillips, Claire, Fay, Michael, Nishikawa, Ryo, Cairncross, Gregory J., Roa, Wilson, Osoba, David, Rossiter, John P., Sahgal, Arjun, Hirte, Hal, Laigle-Donadey, Florence, Franceschi, Enrico, Chinot, Olivier, Golfinopoulos, Vassilis, Fariselli, Laura, Wick, Antje, Feuvret, Loic, Back, Michael, Tills, Michael, Winch, Chad, Baumert, Brigitta G., Wick, Wolfgang, Ding, Keyue, and Mason, Warren P.

Published
2017
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14. Corrigendum to: Impact of lymphopenia on survival for elderly patients with glioblastoma: A secondary analysis of the CCTG CE.6 (EORTC 26062-22061, TROG 08.02) randomized clinical trial

Author

Song, Andrew J, primary, Ding, Keyue, additional, Alnahhas, Iyad, additional, Laperriere, Normand J, additional, Perry, James, additional, Mason, Warren P, additional, Winch, Chad, additional, O’Callaghan, Chris J, additional, Menten, Johan J, additional, Brandes, Alba A, additional, Phillips, Claire, additional, Fay, Michael F, additional, Nishikawa, Ryo, additional, Osoba, David, additional, Cairncross, J Gregory, additional, Roa, Wilson, additional, Wick, Wolfgang, additional, and Shi, Wenyin, additional

Published
2022
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16. Impact of lymphopenia on survival for elderly patients with glioblastoma: A secondary analysis of the CCTG CE.6 (EORTC 26062-22061, TROG03.01) randomized clinical trial

Author

Song, Andrew J, primary, Ding, Keyue, additional, Alnahhas, Iyad, additional, Laperriere, Normand J, additional, Perry, James, additional, Mason, Warren P, additional, Winch, Chad, additional, O'Callaghan, Chris J, additional, Menten, Johan J, additional, Brandes, Alba A, additional, Phillips, Claire, additional, Fay, Michael F, additional, Nishikawa, Ryo, additional, Osoba, David, additional, Cairncross, Gregory, additional, Roa, Wilson, additional, Wick, Wolfgang, additional, and Shi, Wenyin, additional

Published
2021
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17. Minimal important differences for interpreting health-related quality of life scores from the EORTC QLQ-C30 in lung cancer patients participating in randomized controlled trials

Author

Maringwa, John T., Quinten, Chantal, King, Madeleine, Ringash, Jolie, Osoba, David, Coens, Corneel, Martinelli, Francesca, Vercauteren, Jurgen, Cleeland, Charles S., Flechtner, Henning, Gotay, Carolyn, Greimel, Eva, Taphoorn, Martin J., Reeve, Bryce B., Koch, Joseph Schmucker-Von, Weis, Joachim, Smit, Egbert F., van Meerbeeck, Jan P., Bottomley, Andrew, and on behalf of the EORTC PROBE project and the Lung Cancer Group

Published
2011
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20. A Global Analysis of Multitrial Data Investigating Quality of Life and Symptoms as Prognostic Factors for Survival in Different Tumor Sites

Author

Quinten, Chantal, Martinelli, Francesca, Coens, Corneel, Sprangers, Mirjam A. G., Ringash, Jolie, Gotay, Carolyn, Bjordal, Kristin, Greimel, Eva, Reeve, Bryce B., Maringwa, John, Ediebah, Divine E., Zikos, Efstathios, King, Madeleine T., Osoba, David, Taphoorn, Martin J., Flechtner, Henning, Schmucker-Von Koch, Joseph, Weis, Joachim, and Bottomley, Andrew

Published
2014
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22. Examining the relationships among health-related quality-of-life indicators in cancer patients participating in clinical trials: a pooled study of baseline EORTC QLQ-C30 data

Author

Martinelli, Francesca, Quinten, Chantal, Maringwa, John T, Coens, Corneel, Vercauteren, Jurgen, Cleeland, Charles S, Flechtner, Henning, Gotay, Carolyn, Greimel, Eva, King, Madeleine, Mendoza, Tito, Osoba, David, Reeve, Bryce B, Ringash, Jolie, Koch, Joseph Schmucker-Von, Shi, Qiuling, Taphoorn, Martin J, Weis, Joachim, and Bottomley, Andrew

Published
2011
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23. Impact of lymphopenia on survival for elderly patients with glioblastoma: A secondary analysis of the CCTG CE.6 (EORTC 26062-22061, TROG03.01) randomized clinical trial.

Author

Song, Andrew Jehyun, primary, Ding, Keyue, additional, Laperriere, Normand, additional, Perry, James R., additional, Mason, Warren P., additional, Winch, Chad, additional, O'Callaghan, Christopher J., additional, Menten, Johan, additional, Brandes, Alba Ariela, additional, Phillips, Claire, additional, Fay, Michael F., additional, Nishikawa, Ryo, additional, Osoba, David, additional, Cairncross, Gregory, additional, Roa, Wilson, additional, Wick, Wolfgang, additional, and Shi, Wenyin, additional

Published
2020
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24. Temozolomide does not meaningfully reduce seizure frequency in elderly glioblastoma patients (614)

Author

Climans, Seth, primary, Brandes, Alba, additional, Cairncross, J. Greg, additional, Ding, Keyue, additional, Fay, Michael, additional, Laperriere, Normand, additional, Menten, Johan, additional, Nishikawa, Ryo, additional, O’Callaghan, Christopher, additional, Osoba, David, additional, Perry, James, additional, Phillips, Claire, additional, Roa, Wilson, additional, Winch, Chad, additional, and Mason, Warren, additional

Published
2020
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39. Measuring chemotherapy-induced nausea and emesis

Author

Martin, Charles G., Rubenstein, Edward B., Elting, Linda S., Kim, Young Jun, and Osoba, David

Subjects
Vomiting -- Care and treatment, Vomiting -- Causes of, Nausea -- Causes of, Nausea -- Care and treatment, Quality of life -- Analysis, Health
Published
2003

44. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology

Author

Aaronson, Neil K., Ahmedzai, Sam, Bergman, Bengt, Bullinger, Monika, Cull, Ann, Duez, Nicole J., Filiberti, Antonio, Flechtner, Henning, Fleishman, Stewart B., Haes, Johanna C.J.M. de, Kaasa, Stein, Klee, Marianne, Osoba, David, Razavi, Darius, Rofe, Peter B., Schraub, Simon, Sneeuw, Kommer, Sullivan, Marianne, and Takeda, Fumikazu

Subjects
Quality of life -- Measurement, Oncology -- Standards, Clinical trials -- Standards, Health, European Organization for Research and Treatment of Cancer -- Standards
Abstract

Background. In 1986, the European Organization for Research and Treatment of Cancer (EORTC) initiated a research program to develop an integrated, modular approach for evaluating the quality of life of patients participating in international clinical trials. Purpose: We report here the results of an international field study of the practicality, reliability, and validity of the EORTC QLQ-C30, the current core questionnaire. The QLQ-C30 incorporates nine multi-item scales: five functional scales (physical, role, cognitive, emotional, and social); three symptom scales (fatigue, pain, and nausea and vomiting); and a global health and quality-of-life scale. Several single-item symptom measures are also included. Methods: The questionnaire was administered before treatment and once during treatment to 305 patients with nonresectable lung cancer from centers in 13 countries. Clinical variables assessed included disease stage, weight loss, performance status, and treatment toxicity. Results: The average time required to complete the questionnaire was approximately 11 minutes, and most patients required no assistance. The data supported the hypothesized scale structure of the questionnaire with the exception of role functioning (work and household activities), which was also the only multi-item scale that failed to meet the minimal standards for reliability (Cronbach's alpha coefficient [is greater than or equal to].70) either before or during treatment. Validity was shown by three findings. First, while all interscale correlations were statistically significant, the correlation was moderate, indicating that the scales were assessing distinct components of the quality-of-life construct. Second, most of the functional and symptom measures discriminated clearly between patients differing in clinical status as defined by the Eastern Cooperative Oncology Group performance status scale, weight loss, and treatment toxicity. Third, there were statistically significant changes, in the expected direction, in physical and role functioning, global quality of life, fatigue, and nausea and vomiting, for patients whose performance status had improved or worsened during treatment. The reliability and validity of the questionnaire were highly consistent across the three language-cultural groups studied: patients from English-speaking countries, Northern Europe, and Southern Europe. Conclusions: These results support the EORTC QLQ-C30 as a reliable and valid measure of the quality of life of cancer patients in multicultural clinical research settings. Work is ongoing to examine the performance of the questionnaire among more heterogenous patient samples and in phase II and phase III clinical trials. [J Natl Cancer Inst 85:365-376, 1993]

Published
1993

46. Quality-of-life assessment: patient compliance with questionnaire completion

Author

Sadura, Anna, Pater, Joseph, Osoba, David, Levine, Mark, Palmer, Michael, and Bennett, Katherine

Subjects
Quality of life -- Evaluation, Clinical trials -- Management, Cancer patients -- Surveys, Health
Abstract

Background: Previous investigators have found that compliance with quality-of-life data collection on cancer clinical trials is poor. There is general belief that collecting complete quality-of-life data is at present an unachievable goal. Purpose: We assessed the completeness of quality-of-life data collection on trials instituted by the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG), since incorporation of quality-of-life outcomes into trials became mandatory for the group. Methods: Data from three NCIC CTG trials in which quality of life was a study end point were examined to determine the extent to which protocol specifications were met with respect to questionnaire completion. Two of the studies examined adjuvant therapies, and one examined anti-emetics. In two trials, the quality-of-life questionnaire of the European Organization for Research and Treatment of Cancer was used; in the other, the Breast Cancer Chemotherapy Questionnaire. Results: Patient compliance with questionnaire completion was unexpectedly high: More than 95% of the scheduled questionnaires were returned, and more than 99% of the questions were answered. Conclusions: We attribute this success to a comprehensive set of measures taken to enhance compliance on these studies. Which of these measures was most contributory requires further investigation, as does the issue of whether similar results can be obtained in other circumstances. Implications: It seems that the commonly held belief that quality-of-life data cannot be successfully collected in multicenter cancer trials is incorrect. [J Natl Cancer Inst 84:1023-1026, 1992]

Published
1992

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