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3. Acute and Postacute Clinical Characteristics of Coronavirus Disease 2019 in Children in Japan

Author

Katsuta, Tomohiro, Aizawa, Yuta, Shoji, Kensuke, Shimizu, Naoki, Okada, Kenji, Nakano, Takashi, Kamiya, Hajime, Amo, Kiyoko, Ishiwada, Naruhiko, Iwata, Satoshi, Oshiro, Makoto, Okabe, Nobuhiko, Korematsu, Seigo, Suga, Shigeru, Tsugawa, Takeshi, Nishimura, Naoko, Hishiki, Haruka, Fujioka, Masashi, Hosoya, Mitsuaki, Mizuno, Yumi, Miyairi, Isao, Miyazaki, Chiaki, Morishima, Tsuneo, Yoshikawa, Tetsushi, Wada, Taizo, Ouchi, Kazunobu, Moriuchi, Hiroyuki, Tanaka-Taya, Keiko, and Saitoh, Akihiko

Published
2022
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4. A global point prevalence survey of antimicrobial use in neonatal intensive care units: The no-more-antibiotics and resistance (NO-MAS-R) study

Author

Prusakov, Pavel, Goff, Debra A., Wozniak, Phillip S., Cassim, Azraa, Scipion, Catherine E.A., Urzúa, Soledad, Ronchi, Andrea, Zeng, Lingkong, Ladipo-Ajayi, Oluwaseun, Aviles-Otero, Noelia, Udeigwe-Okeke, Chisom R., Melamed, Rimma, Silveira, Rita C., Auriti, Cinzia, Beltrán-Arroyave, Claudia, Zamora-Flores, Elena, Sanchez-Codez, Maria, Donkor, Eric S., Kekomäki, Satu, Mainini, Nicoletta, Trochez, Rosalba Vivas, Casey, Jamalyn, Graus, Juan M., Muller, Mallory, Singh, Sara, Loeffen, Yvette, Pérez, María Eulalia Tamayo, Ferreyra, Gloria Isabel, Lima-Rogel, Victoria, Perrone, Barbara, Izquierdo, Giannina, Cernada, María, Stoffella, Sylvia, Ekenze, Sebastian Okwuchukwu, de Alba-Romero, Concepción, Tzialla, Chryssoula, Pham, Jennifer T., Hosoi, Kenichiro, Consuegra, Magdalena Cecilia Calero, Betta, Pasqua, Hoyos, O. Alvaro, Roilides, Emmanuel, Naranjo-Zuñiga, Gabriela, Oshiro, Makoto, Garay, Victor, Mondì, Vito, Mazzeo, Danila, Stahl, James A., Cantey, Joseph B., Monsalve, Juan Gonzalo Mesa, Normann, Erik, Landgrave, Lindsay C., Mazouri, Ali, Avila, Claudia Alarcón, Piersigilli, Fiammetta, Trujillo, Monica, Kolman, Sonya, Delgado, Verónica, Guzman, Veronica, Abdellatif, Mohamed, Monterrosa, Luis, Tina, Lucia Gabriella, Yunis, Khalid, Rodriguez, Marco Antonio Belzu, Saux, Nicole Le, Leonardi, Valentina, Porta, Alessandro, Latorre, Giuseppe, Nakanishi, Hidehiko, Meir, Michal, Manzoni, Paolo, Norero, Ximena, Hoyos, Angela, Arias, Diana, Sánchez, Rubén García, Medoro, Alexandra K., and Sánchez, Pablo J.

Published
2021
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5. Outcomes in symptomatic preterm infants with postnatal cytomegalovirus infection

Author

Takemoto, Koji, Oshiro, Makoto, Sato, Yoshiaki, Yamamoto, Hikaru, Ito, Masatoki, Hayashi, Seiji, Kato, Eiko, Kato, Yuichi, and Hayakawa, Masahiro

Subjects
case-control studies, growth & development, premature birth, patient outcome assessment, cytomegalovirus infections
Abstract

Premature infants are at risk for developing symptomatic postnatal cytomegalovirus (CMV) disease, including sepsis-like syndrome. We performed a retrospective case–control study including infants born before 32 weeks of gestation and diagnosed with symptomatic postnatal CMV infection during the neonatal period. Neurodevelopmental outcome was evaluated using the Kyoto Scale of Psychological Development 2001 at 18 months of corrected age and at 3 years of age. Twenty-four infants were diagnosed with postnatal CMV infection; of them, 14 had sepsis-like symptoms and 10 had laboratory test abnormalities only. Home oxygen therapy was used significantly higher in the CMV-positive group compared with the control group at hospital discharge (52% vs 21%, P=0.032). The incidence of neurodevelopmental impairment was not significantly different between the two groups at 18 months of corrected age (29% vs 17%, P=0.48) and at 3 years of age (43% vs 29%, P=0.34). Postnatal CMV infection did not have a significant influence on neurodevelopmental outcomes of symptomatic preterm infants, although those in the CMV-positive group appeared worse. Larger studies with long-term follow-up are needed for a better understanding of continued neurodevelopmental outcomes in preterm infants with postnatal CMV infection., This is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Published
2021

7. Prognostic factors of hydrops fetalis with pleural effusion

Author

Nakayama, Atsushi, Oshiro, Makoto, Yamada, Yasumasa, Hattori, Tetsuo, Wakano, Yasuhiro, Hayashi, Seiji, Kokubo, Minoru, Takemoto, Koji, Honda, Shigeru, Ieda, Kuniko, Yamamoto, Hikaru, Kouwaki, Masanori, Yokoi, Kyoko, Shinohara, Osamu, Kato, Takenori, Miyata, Masafumi, Tanaka, Taihei, and Hayakawa, Masahiro

Published
2017
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11. The clinical characteristics of pediatric coronavirus disease 2019 in 2020 in Japan

Author

Katsuta, Tomohiro, primary, Shimizu, Naoki, additional, Okada, Kenji, additional, Tanaka‐Taya, Keiko, additional, Nakano, Takashi, additional, Kamiya, Hajime, additional, Amo, Kiyoko, additional, Ishiwada, Naruhiko, additional, Iwata, Satoshi, additional, Oshiro, Makoto, additional, Okabe, Nobuhiko, additional, Kira, Ryutaro, additional, Korematsu, Seigo, additional, Suga, Shigeru, additional, Tsugawa, Takeshi, additional, Nishimura, Naoko, additional, Hishiki, Haruka, additional, Fujioka, Masashi, additional, Hosoya, Mitsuaki, additional, Mizuno, Yumi, additional, Mine, Mahito, additional, Miyairi, Isao, additional, Miyazaki, Chiaki, additional, Morioka, Ichiro, additional, Morishima, Tsuneo, additional, Yoshikawa, Tetsushi, additional, Wada, Taizo, additional, Azuma, Hiroshi, additional, Kusuhara, Koichi, additional, Ouchi, Kazunobu, additional, Saitoh, Akihiko, additional, and Moriuchi, Hiroyuki, additional

Published
2021
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13. A global point prevalence survey of antimicrobial use in neonatal intensive care units: The no-more-antibiotics and resistance (NO-MAS-R) study.

Author

UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de néonatologie, Prusakov, Pavel, Goff, Debra A, Wozniak, Phillip S, Cassim, Azraa, Scipion, Catherine E A, Urzúa, Soledad, Ronchi, Andrea, Zeng, Lingkong, Ladipo-Ajayi, Oluwaseun, Aviles-Otero, Noelia, Udeigwe-Okeke, Chisom R, Melamed, Rimma, Silveira, Rita C, Auriti, Cinzia, Beltrán-Arroyave, Claudia, Zamora-Flores, Elena, Sanchez-Codez, Maria, Donkor, Eric S, Kekomäki, Satu, Mainini, Nicoletta, Trochez, Rosalba Vivas, Casey, Jamalyn, Graus, Juan M, Muller, Mallory, Singh, Sara, Loeffen, Yvette, Pérez, María Eulalia Tamayo, Ferreyra, Gloria Isabel, Lima-Rogel, Victoria, Perrone, Barbara, Izquierdo, Giannina, Cernada, María, Stoffella, Sylvia, Ekenze, Sebastian Okwuchukwu, de Alba-Romero, Concepción, Tzialla, Chryssoula, Pham, Jennifer T, Hosoi, Kenichiro, Consuegra, Magdalena Cecilia Calero, Betta, Pasqua, Hoyos, O Alvaro, Roilides, Emmanuel, Naranjo-Zuñiga, Gabriela, Oshiro, Makoto, Garay, Victor, Mondì, Vito, Mazzeo, Danila, Stahl, James A, Cantey, Joseph B, Monsalve, Juan Gonzalo Mesa, Normann, Erik, Landgrave, Lindsay C, Mazouri, Ali, Avila, Claudia Alarcón, Piersigilli, Fiammetta, Trujillo, Monica, Kolman, Sonya, Delgado, Verónica, Guzman, Veronica, Abdellatif, Mohamed, Monterrosa, Luis, Tina, Lucia Gabriella, Yunis, Khalid, Rodriguez, Marco Antonio Belzu, Saux, Nicole Le, Leonardi, Valentina, Porta, Alessandro, Latorre, Giuseppe, Nakanishi, Hidehiko, Meir, Michal, Manzoni, Paolo, Norero, Ximena, Hoyos, Angela, Arias, Diana, Sánchez, Rubén García, Medoro, Alexandra K, Sánchez, Pablo J, Global NEO-ASP Study Group, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de néonatologie, Prusakov, Pavel, Goff, Debra A, Wozniak, Phillip S, Cassim, Azraa, Scipion, Catherine E A, Urzúa, Soledad, Ronchi, Andrea, Zeng, Lingkong, Ladipo-Ajayi, Oluwaseun, Aviles-Otero, Noelia, Udeigwe-Okeke, Chisom R, Melamed, Rimma, Silveira, Rita C, Auriti, Cinzia, Beltrán-Arroyave, Claudia, Zamora-Flores, Elena, Sanchez-Codez, Maria, Donkor, Eric S, Kekomäki, Satu, Mainini, Nicoletta, Trochez, Rosalba Vivas, Casey, Jamalyn, Graus, Juan M, Muller, Mallory, Singh, Sara, Loeffen, Yvette, Pérez, María Eulalia Tamayo, Ferreyra, Gloria Isabel, Lima-Rogel, Victoria, Perrone, Barbara, Izquierdo, Giannina, Cernada, María, Stoffella, Sylvia, Ekenze, Sebastian Okwuchukwu, de Alba-Romero, Concepción, Tzialla, Chryssoula, Pham, Jennifer T, Hosoi, Kenichiro, Consuegra, Magdalena Cecilia Calero, Betta, Pasqua, Hoyos, O Alvaro, Roilides, Emmanuel, Naranjo-Zuñiga, Gabriela, Oshiro, Makoto, Garay, Victor, Mondì, Vito, Mazzeo, Danila, Stahl, James A, Cantey, Joseph B, Monsalve, Juan Gonzalo Mesa, Normann, Erik, Landgrave, Lindsay C, Mazouri, Ali, Avila, Claudia Alarcón, Piersigilli, Fiammetta, Trujillo, Monica, Kolman, Sonya, Delgado, Verónica, Guzman, Veronica, Abdellatif, Mohamed, Monterrosa, Luis, Tina, Lucia Gabriella, Yunis, Khalid, Rodriguez, Marco Antonio Belzu, Saux, Nicole Le, Leonardi, Valentina, Porta, Alessandro, Latorre, Giuseppe, Nakanishi, Hidehiko, Meir, Michal, Manzoni, Paolo, Norero, Ximena, Hoyos, Angela, Arias, Diana, Sánchez, Rubén García, Medoro, Alexandra K, Sánchez, Pablo J, and Global NEO-ASP Study Group

Abstract

BACKGROUND: Global assessment of antimicrobial agents prescribed to infants in the neonatal intensive care unit (NICU) may inform antimicrobial stewardship efforts. METHODS: We conducted a one-day global point prevalence study of all antimicrobials provided to NICU infants. Demographic, clinical, and microbiologic data were obtained including NICU level, census, birth weight, gestational/chronologic age, diagnoses, antimicrobial therapy (reason for use; length of therapy), antimicrobial stewardship program (ASP), and 30-day in-hospital mortality. FINDINGS: On July 1, 2019, 26% of infants (580/2,265; range, 0-100%; median gestational age, 33 weeks; median birth weight, 1800 g) in 84 NICUs (51, high-income; 33, low-to-middle income) from 29 countries (14, high-income; 15, low-to-middle income) in five continents received ≥1 antimicrobial agent (92%, antibacterial; 19%, antifungal; 4%, antiviral). The most common reasons for antibiotic therapy were "rule-out" sepsis (32%) and "culture-negative" sepsis (16%) with ampicillin (40%), gentamicin (35%), amikacin (19%), vancomycin (15%), and meropenem (9%) used most frequently. For definitive treatment of presumed/confirmed infection, vancomycin (26%), amikacin (20%), and meropenem (16%) were the most prescribed agents. Length of therapy for culture-positive and "culture-negative" infections was 12 days (median; IQR, 8-14) and 7 days (median; IQR, 5-10), respectively. Mortality was 6% (42%, infection-related). An NICU ASP was associated with lower rate of antibiotic utilization (p = 0·02). INTERPRETATION: Global NICU antibiotic use was frequent and prolonged regardless of culture results. NICU-specific ASPs were associated with lower antibiotic utilization rates, suggesting the need for their implementation worldwide. FUNDING: Merck & Co.; The Ohio State University College of Medicine Barnes Medical Student Research Scholarship.

Published
2021

17. Effect of a vaccine information statement (VIS) on immunization status and parental knowledge, attitudes, and beliefs regarding infant immunization in Japan

Author

Saitoh, Aya, primary, Saitoh, Akihiko, additional, Katsuta, Tomohiro, additional, Mine, Mahito, additional, Kamiya, Hajime, additional, Miyairi, Isao, additional, Ishiwada, Naruhiko, additional, Oshiro, Makoto, additional, Kira, Ryutaro, additional, Shimizu, Naoki, additional, Suga, Shigeru, additional, Tsugawa, Takeshi, additional, Fujioka, Masashi, additional, Miyazaki, Chiaki, additional, Morioka, Ichiro, additional, Korematsu, Seigo, additional, Nakano, Takashi, additional, Tanaka-Taya, Keiko, additional, Yoshikawa, Tetsushi, additional, Iwata, Satoshi, additional, Kusuhara, Koichi, additional, Azuma, Hiroshi, additional, Moriuchi, Hiroyuki, additional, Okabe, Nobuhiko, additional, Hosoya, Mitsuaki, additional, Tsutsumi, Hiroyuki, additional, and Okada, Kenji, additional

Published
2020
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20. Factors related to survival discharge in trisomy 18: A retrospective multicenter study

Author

Kato, Eiko, primary, Kitase, Yuma, additional, Tachibana, Takashi, additional, Hattori, Tetsuo, additional, Saito, Akiko, additional, Muramatsu, Yukako, additional, Takemoto, Koji, additional, Yamamoto, Hikaru, additional, Hayashi, Seiji, additional, Yasuda, Ayako, additional, Kato, Yuichi, additional, Ieda, Kuniko, additional, Oshiro, Makoto, additional, Sato, Yoshiaki, additional, and Hayakawa, Masahiro, additional

Published
2019
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22. MIRAGE syndrome is a rare cause of 46,XY DSD born SGA without adrenal insufficiency

Author

Shima, Hirohito, primary, Hayashi, Mie, additional, Tachibana, Takashi, additional, Oshiro, Makoto, additional, Amano, Naoko, additional, Ishii, Tomohiro, additional, Haruna, Hidenori, additional, Igarashi, Maki, additional, Kon, Masafumi, additional, Fukuzawa, Ryuji, additional, Tanaka, Yukichi, additional, Fukami, Maki, additional, Hasegawa, Tomonobu, additional, and Narumi, Satoshi, additional

Published
2018
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23. Effects of the early administration of sivelestat sodium on bronchopulmonary dysplasia in infants: A retrospective cohort study

Author

Ogawa, Ryo, primary, Mori, Rintaro, additional, Iida, Koichi, additional, Uchida, Yumiko, additional, Oshiro, Makoto, additional, Kageyama, Misao, additional, Kato, Yuichi, additional, Tanaka, Taihei, additional, Nakata, Yusei, additional, Nishimura, Yutaka, additional, Hokuto, Isamu, additional, Bonno, Motoki, additional, Matsumoto, Naoko, additional, Ito, Masato, additional, Takahashi, Noriko, additional, and Namba, Fumihiko, additional

Published
2017
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25. MBTPS2 mutation causes BRESEK/BRESHECK syndrome

Author

Naiki, Misako, primary, Mizuno, Seiji, additional, Yamada, Kenichiro, additional, Yamada, Yasukazu, additional, Kimura, Reiko, additional, Oshiro, Makoto, additional, Okamoto, Nobuhiko, additional, Makita, Yoshio, additional, Seishima, Mariko, additional, and Wakamatsu, Nobuaki, additional

Published
2011
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