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251 results on '"Osella Abate, S."'

2. Global patterns of care in advanced stage mycosis fungoides/Sezary syndrome: a multicenter retrospective follow-up study from the Cutaneous Lymphoma International Consortium

Author

Quaglino, P., Maule, M., Prince, H.M., Porcu, P., Horwitz, S., Duvic, M., Talpur, R., Vermeer, M., Bagot, M., Guitart, J., Papadavid, E., Sanches, J.A., Hodak, E., Sugaya, M., Berti, E., Ortiz-Romero, P., Pimpinelli, N., Servitje, O., Pileri, A., Zinzani, P.L., Estrach, T., Knobler, R., Stadler, R., Fierro, M.T., Alberti Violetti, S., Amitay-Laish, I., Antoniou, C., Astrua, C., Chaganti, S., Child, F., Combalia, A., Fabbro, S., Fava, P., Grandi, V., Jonak, C., Martinez-Escala, E., Kheterpal, M., Kim, E.J., McCormack, C., Miyagaki, T., Miyashiro, D., Morris, S., Muniesa, C., Nikolaou, V., Ognibene, G., Onida, F., Osella-Abate, S., Porkert, S., Postigo-Llorente, C., Ram-Wolff, C., Ribero, S., Rogers, K., Sanlorenzo, M., Stranzenbach, R., Spaccarelli, N., Stevens, A., Zugna, D., Rook, A.H., Geskin, L.J., Willemze, R., Whittaker, S., Hoppe, R., Scarisbrick, J., and Kim, Y.

Published
2017
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20. Microenvironment in cutaneous melanomas: a gene expression profile study may explain the role of histological regression

Author

Osella‐Abate, S., primary, Vignale, C., additional, Annaratone, L., additional, Nocifora, A., additional, Bertero, L., additional, Castellano, I., additional, Avallone, G., additional, Conti, L., additional, Quaglino, P., additional, Picciotto, F., additional, Senetta, R., additional, Papotti, M.G., additional, Cassoni, P., additional, and Ribero, S., additional

Published
2020
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23. Corrigendum to 'Factors associated with sentinel lymph node status and prognostic role of completion lymph node dissection for thick melanoma' [Eur J Surg Oncol 46 2 (2019) 263–271] (European Journal of Surgical Oncology (2020) 46(2) (263–271), (S0748798319308807), (10.1016/j.ejso.2019.09.189))

Author

Boada, A., Tejera-Vaquerizo, A., Ribero, S., Puig, S., Moreno-Ramirez, D., Quaglino, P., Osella-Abate, S., Cassoni, P., Malvehy, J., Carrera, C., Pigem, R., Barreiro-Capurro, A., Requena, C., Traves, V., Manrique-Silva, E., Fernandez-Orland, A., Ferrandiz, L., Garcia-Senosiain, O., Fernandez-Figueras, M. T., Ferrandiz, C., Nagore, E., Espinosa, N., Gimenez, P., Perez, J., Podlipnik, S., Rull, R., Vidal-Sicart, S., Yelamos, O., Fiero, M. T., Bolumar, I., Pla, A., Quer-Pi sunyer, A., Manzano, J. L., Pascual, I., Jaka, A., and Sanchez-Lucas, M.

Published
2020

28. Corrigendum: Global patterns of care in advanced stage mycosis fungoides/Sezary syndrome: A multicenter retrospective follow-up study from the Cutaneous Lymphoma International Consortium (Annals of Oncology (2017) 28 (2517-2525) DOI: 10.1093/annonc/mdx352)

Author

Quaglino, P., Maule, M., Prince, H. M., Porcu, P., Horwitz, S., Duvic, M., Talpur, R., Vermeer, M., Bagot, M., Guitart, J., Papadavid, E., Sanches, J. A., Hodak, E., Sugaya, M., Berti, E., Ortiz-Romero, P., Pimpinelli, N., Servitje, O., Pileri, A., Zinzani, P. L., Estrach, T., Knobler, R., Stadler, R., Fierro, M. T., Alberti Violetti, S., Amitay-Laish, I., Antoniou, C., Astrua, C., Chaganti, S., Child, F., Combalia, A., Fabbro, S., Fava, P., Grandi, V., Jonak, C., Martinez-Escala, E., Kheterpal, M., Kim, E. J., Mccormack, C., Miyagaki, T., Miyashiro, D., Morris, S., Muniesa, C., Nikolaou, V., Ognibene, G., Onida, F., Osella-Abate, S., Porkert, S., Postigo-Llorente, C., Ram-Wolff, C., Ribero, S., Rogers, K., Sanlorenzo, M., Stranzenbach, R., Spaccarelli, N., Stevens, A., Zugna, D., Rook, A. H., Geskin, L. J., Willemze, R., Whittaker, S., Hoppe, R., Scarisbrick, J., and Kim, Y.

Published
2019

29. Corrigendum: Global patterns of care in advanced stage mycosis fungoides/Sezary syndrome: A multicenter retrospective follow-up study from the Cutaneous Lymphoma International Consortium (Annals of Oncology (2017) 28 (2517-2525) DOI: 10.1093/annonc/mdx352)

Author

Quaglino, P. Maule, M. Prince, H.M. Porcu, P. Horwitz, S. Duvic, M. Talpur, R. Vermeer, M. Bagot, M. Guitart, J. Papadavid, E. Sanches, J.A. Hodak, E. Sugaya, M. Berti, E. Ortiz-Romero, P. Pimpinelli, N. Servitje, O. Pileri, A. Zinzani, P.L. Estrach, T. Knobler, R. Stadler, R. Fierro, M.T. Alberti Violetti, S. Amitay-Laish, I. Antoniou, C. Astrua, C. Chaganti, S. Child, F. Combalia, A. Fabbro, S. Fava, P. Grandi, V. Jonak, C. Martinez-Escala, E. Kheterpal, M. Kim, E.J. McCormack, C. Miyagaki, T. Miyashiro, D. Morris, S. Muniesa, C. Nikolaou, V. Ognibene, G. Onida, F. Osella-Abate, S. Porkert, S. Postigo-Llorente, C. Ram-Wolff, C. Ribero, S. Rogers, K. Sanlorenzo, M. Stranzenbach, R. Spaccarelli, N. Stevens, A. Zugna, D. Rook, A.H. Geskin, L.J. Willemze, R. Whittaker, S. Hoppe, R. Scarisbrick, J. Kim, Y.

Abstract

In the original article, the affiliation number 16 for authors E. Berti and S. Alberti Violetti was incorrect. It originally read: 'Dermatologic Clinic, University of Milano, Milano, Italy' and has now been changed to 'Department of Dermatology, Fondazione Cà Granda, IRCCS,OMP, Milano, Italy'. © The Author(s) 2018. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Published
2019

30. Corrections to “Global patterns of care in advanced stage mycosis fungoides/Sezary syndrome: a multicenter retrospective follow-up study from the Cutaneous Lymphoma International Consortium”

Author

Quaglino, P., primary, Maule, M., additional, Prince, H.M., additional, Porcu, P., additional, Horwitz, S., additional, Duvic, M., additional, Talpur, R., additional, Vermeer, M., additional, Bagot, M., additional, Guitart, J., additional, Papadavid, E., additional, Sanches, J.A., additional, Hodak, E., additional, Sugaya, M., additional, Berti, E., additional, Ortiz-Romero, P., additional, Pimpinelli, N., additional, Servitje, O., additional, Pileri, A., additional, Zinzani, P.L., additional, Estrach, T., additional, Knobler, R., additional, Stadler, R., additional, Fierro, M.T., additional, Alberti Violetti, S., additional, Amitay-Laish, I., additional, Antoniou, C., additional, Astrua, C., additional, Chaganti, S., additional, Child, F., additional, Combalia, A., additional, Fabbro, S., additional, Fava, P., additional, Grandi, V., additional, Jonak, C., additional, Martinez-Escala, E., additional, Kheterpal, M., additional, Kim, E.J., additional, McCormack, C., additional, Miyagaki, T., additional, Miyashiro, D., additional, Morris, S., additional, Muniesa, C., additional, Nikolaou, V., additional, Ognibene, G., additional, Onida, F., additional, Osella-Abate, S., additional, Porkert, S., additional, Postigo-Llorente, C., additional, Ram-Wolff, C., additional, Ribero, S., additional, Rogers, K., additional, Sanlorenzo, M., additional, Stranzenbach, R., additional, Spaccarelli, N., additional, Stevens, A., additional, Zugna, D., additional, Rook, A.H., additional, Geskin, L.J., additional, Willemze, R., additional, Whittaker, S., additional, Hoppe, R., additional, Scarisbrick, J., additional, and Kim, Y., additional

Published
2019
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31. Prognostic impact of regression in patients with primary cutaneous melanoma >1 mm in thickness

Author

Ribero S, Galli F, Osella-Abate S, Bertero L, Cattaneo L, Merelli B, Tondini C, Ghilardi L, De Giorgi V, Occelli M, Quaglino P, Cassoni P, Palmieri G, Massi D, and Mandala M on behalf of the Italian Melanoma Intergroup (IMI).

Subjects
mitosis, melanoma, prognosis
Abstract

Background: The impact of histologic regression on sentinel lymph node biopsy (SLNB) status and on clinical outcome is uncertain. Objective: To investigate whether and to what extent regression \75% is able to predict SLNB status and clinical outcome of patients with melanoma [1-mm thick. Methods: The study included patients with diagnoses given at 4 centers of the Italian Melanoma Intergroup. Univariable and multivariable Cox proportional hazard models stratified by center were used to analyze the effect of regression on disease-free interval and melanoma-specific survival. Results: Out of 1182 patients given primary cutaneous melanoma diagnoses during 1998-2015 with a Breslow thickness [1 mm, 954 (304 with and 650 without regression) were included in the analysis. The proportion of patients with a positive SLNB was lower in patients with regression than without (24.4% vs 31.6%, chi-squared test P = .0368). At multivariable analysis, no association was detected between regression and disease-free interval (hazard ratio 1.11, 95% confidence interval 0.85-1.46; P = .4509) or melanoma-specific survival (hazard ratio 1.05, 95% confidence interval 0.77-1.44; P = .7600). Limitation: Retrospective analysis. Conclusion: In our series, regression was not an independent prognostic factor in primary cutaneous melanoma patients with Breslow thickness [1 mm whereas it was associated with a lower incidence of SLNB positivity.

Published
2018

32. Microenvironment in cutaneous melanomas: a gene expression profile study may explain the role of histological regression.

Author

Osella‐Abate, S., Vignale, C., Annaratone, L., Nocifora, A., Bertero, L., Castellano, I., Avallone, G., Conti, L., Quaglino, P., Picciotto, F., Senetta, R., Papotti, M.G., Cassoni, P., and Ribero, S.

Subjects
*GENE expression profiling, *MELANOMA, *MICROPHTHALMIA-associated transcription factor, *IPILIMUMAB
Abstract

Gene expression analysis was performed on a series ( I n i = 46) of >10% regressed melanoma and a control group ( I n i = 50) of non-regressed (regression <= 10%) melanoma patients who attended the Dermatology Clinic at Turin University Hospital (Table 1). In particular, 12 genes resulted up-regulated in melanoma samples with histological regression ( I RPS6 i , I IL11RA i , I TP53 i , I NOTCH1 i , I EGR2 i , I EGR1 i , I ABL1 i , I CFD i , I ZNF205 i , I NFATC1 i , I ICOSLG i and I ECIST i ) and seven genes up-regulated in melanomas without histological regression ( I P i < 0.01) ( I IL1B i , I BIRC5 i , I PBK i , I CDK1 i , I CXCL1 i and I CD47 i ) (Fig. [Extracted from the article]

Published
2021
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36. Supplementary Material for: Multiple Lymph Node Basin Drainage in Trunk Melanoma Is Not Associated with Survival of Sentinel Lymph Node-Positive Patients

Author

Ribero, S., Osella Abate, S., Pasquali, S., Rossi, C.R., Borgognoni, L., Piazzalunga, D., Solari, N., Schiavon, M., Brandani, P., Ansaloni, L., Ponte, E., Silan, F., Sommariva, A., Bellucci, F., Macripò, G., Quaglino, P., and On Behalf Of The Italian Melanoma Intergroup (IMI)

Abstract

Objectives: This study was aimed at investigating the prognostic role of multiple lymph node basin drainage (MLBD) in patients with positive sentinel lymph node (SLN) biopsy. Background: MLBD is frequently observed in patients with trunk melanoma undergoing SLN. The prognostic value of MLBD in SLN-positive patients is still debated. Methods: Retrospective data from 312 trunk melanoma patients with positive SLN biopsy (1991-2012) at 6 Italian referral centres were gathered in a multicentre database. MLBD was defined at preoperative lymphoscintigraphy. Clinical and pathological data were analysed for their association with disease-free interval (DFI) and disease-specific (DSS) survival. Results: MLBD was identified in 34.6% of patients (108/312) and was significantly associated with >1 positive SLN (37 vs. 15.2%; p < 0.001) and with >1 positive lymph node (LN) after complete lymph node dissection (CLND) (50.9 vs. 34.8%; p = 0.033). No differences were observed according to drainage pattern in patients who had negative and positive non-SLN at CLND. MLBD was not associated with either DFI or DSS. Multivariate analyses showed that tumour thickness, ulceration, and number of metastatic LNs were associated with worse DFI and DSS, while regression confirmed its protective role in survival. Conclusion: In positive SLN patients, MLBD has no association with survival, which is mainly related to American Joint Committee on Cancer (AJCC) prognostic factors. Since the overall number of positive LNs drives the prognosis, the importance of a CLND in all the positive basins is confirmed.

Published
2017
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41. Phenotypical characterization of circulating cell subsets in pyoderma gangrenosum patients: The experience of the Italian immuno-pathology group

Author

Quaglino, P, Fava, Patrizia, Caproni, M., Antiga, E., De Simone, Clara, Papini, M., Parodi, Andrea, Novelli, Margherita, Osella Abate, S., Ribero, S., Sanlorenzo, M., De Ponti, Erica Maria Rosa, Fierro, M. T., Marzano, A. V., Savoia, P., De Simone, Clara (ORCID:0000-0002-0898-0045), Quaglino, P, Fava, Patrizia, Caproni, M., Antiga, E., De Simone, Clara, Papini, M., Parodi, Andrea, Novelli, Margherita, Osella Abate, S., Ribero, S., Sanlorenzo, M., De Ponti, Erica Maria Rosa, Fierro, M. T., Marzano, A. V., Savoia, P., and De Simone, Clara (ORCID:0000-0002-0898-0045)

Abstract

Background No data are available as to the phenotype of circulating lymphocyte subsets in pyoderma gangrenosum (PG). Aim To analyse the expression of different chemokine receptors associated to T-helper (Th)1 (CCR5), Th2 (CCR4) and Th17 (CCR6), as well as the regulatory T-cell subset (Treg) and dendritic cell polarization in the blood of newly diagnosed untreated PG patients. Materials and methods Multi-parameter flow cytometry was performed on blood samples from 10 PG patients collected at first diagnosis among centres belonging to the Italian Immuno-pathology Group. Blood samples from 10 age- and sex-matched healthy controls (HC) were used as controls. Results PG patients are characterized by an over-expression in the blood of the CD4+CCR5+ and CD4+CCR6+ and a down-regulation of CD4+CCR4+ counts with respect to healthy subjects. Moreover, they show increased levels of myeloid derived dendritic cells type1 and reduced levels of the Treg CD4+CD25highFOXP3+ subset. Conclusions The pattern of chemokine expression argues in favour of a Th1 (CCR5+) and Th17 (CCR6+) polarization with a down-regulation of Th2 (CCR4+).

Published
2016

43. 'From the Aosta Valley to the Sicily it is always melanoma but..' : results of a multicentric Italian study from the GIPMe

Author

Fava, P, Chiarugi, A, Crocetti, E, De Simone, P, Clerico, Mr, Fargnoli, Mc, Filosa, G, Pimpinelli, N, Bottoni, U, Calvieri, S, Calzavara Pinton PG, Cannavo', Serafinella, Cavicchini, S, Colombo, E, Fantini, F, Ferreli, C, Fimiani, M, Lisi, P, Manganoni, Am, Osella Abate, S, Papini, M, Peris, K, Rubegni, P, Salvini, C, Savoia, P, Simonacci, M, Strippoli, D, Zaccagna, A, Astrua, C, Atzori, L, Eibenshutz, L, Fiorani, R, Girgenti, V, Guarneri, Claudio, Lamberti, A, Pertusi, G, Bernengo, Mg, Quaglino, P, and Gruppo Italiano Polidisciplinare sul Melanoma

Subjects
risk factors, clinicopathologic features, Melanoma
Published
2012

44. Phenotypical characterization of circulating cell subsets in pyoderma gangrenosum patients: the experience of the Italian immuno-pathology group

Author

Quaglino, P, Fava, P, Caproni, M, Antiga, E, DE SIMONE, CLARA, Papini, M, Parodi, A, Novelli, M, Osella-Abate, S, Ribero, S, Sanlorenzo, M, Ponti, R, Fierro, MT, Marzano, AV, Savoia, P, Quaglino, P, Fava, P, Caproni, M, Antiga, E, DE SIMONE, CLARA, Papini, M, Parodi, A, Novelli, M, Osella-Abate, S, Ribero, S, Sanlorenzo, M, Ponti, R, Fierro, MT, Marzano, AV, and Savoia, P

Published
2015

46. Phenotypical characterization of circulating cell subsets in pyoderma gangrenosum patients: the experience of the Italian immuno‐pathology group

Author

Quaglino, P., primary, Fava, P., additional, Caproni, M., additional, Antiga, E., additional, De Simone, C., additional, Papini, M., additional, Parodi, A., additional, Novelli, M., additional, Osella‐Abate, S., additional, Ribero, S., additional, Sanlorenzo, M., additional, Ponti, R., additional, Fierro, M.T., additional, Marzano, A.V., additional, and Savoia, P., additional

Published
2015
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48. Serum levels of the Th1 promoter IL-12 and the Th2 chemokine TARC are elevated in erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis and correlate with soluble Fas ligand expression. An immunoenzymatic study from the Italian Group of Immunopathology

Author

Quaglino, P, Caproni, M, Antiga, E, DEL BIANCO, E, OSELLA ABATE, S, Savoia, P, Frezzolini, A, Schena, D, Marzano, A, Volpi, W, DE SIMONE, C, Parodi, Aurora, Fabbri, P, Bernengo, Mg, and ITALIAN GROUP OF IMMUNOPATHOLOGY

Published
2007

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