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2. Hospital-acquired disability in older heart failure patients decreases independence and increases difficulties in activities of daily living

Author

Nemoto, Shinji, primary, Kasahara, Yusuke, additional, Izawa, Kazuhiro P, additional, Watanabe, Satoshi, additional, Yoshizawa, Kazuya, additional, Takeichi, Naoya, additional, Akao, Keigo, additional, Watanabe, Sato, additional, Mizukoshi, Kei, additional, Suzuki, Norio, additional, Ashikaga, Kohei, additional, Kida, Keisuke, additional, Osada, Naohiko, additional, and Akashi, Yoshihiro J, additional

Published
2022
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3. Hospital-acquired disability in older heart failure patients decreases independence and increases difficulties in activities of daily living.

Author

Nemoto, Shinji, Kasahara, Yusuke, Izawa, Kazuhiro P, Watanabe, Satoshi, Yoshizawa, Kazuya, Takeichi, Naoya, Akao, Keigo, Watanabe, Sato, Mizukoshi, Kei, Suzuki, Norio, Ashikaga, Kohei, Kida, Keisuke, Osada, Naohiko, and Akashi, Yoshihiro J

Subjects
SCIENTIFIC observation, CONFIDENCE intervals, FUNCTIONAL status, ACTIVITIES of daily living, PATIENT readmissions, MANN Whitney U Test, T-test (Statistics), HOSPITAL care of older people, DESCRIPTIVE statistics, CHI-squared test, RESEARCH funding, ADVERSE health care events, BODY mass index, DATA analysis software, HEART failure, LONGITUDINAL method
Abstract

Aims The aim of this study was to clarify whether worsening of independence in activities of daily living (ADL) and also difficulties in ADL are triggered by hospitalization in older patients with heart failure (HF) and whether difficulties in ADL can predict readmission for HF regardless of independence in ADL in these patients. Methods and results We enrolled 241 HF patients in the present multi-institutional, prospective, observational study. The patients were divided according to age into the non-older patient group (<75 years, n = 137) and the older patient group (≥75 years, n = 104). The Katz index and the Performance Measure for Activities of Daily Living-8 (PMADL-8) were used to evaluate independence and difficulties in ADL, respectively. The endpoint of this study was rehospitalization for HF. Independence as indicated by the Katz index at discharge was significantly lower than that before admission only in the older patient group, and the value of the PMADL-8 at discharge was significantly higher than that before admission (P < 0.001). In all patients, after adjusting for the Katz index and other variables, PMADL-8 score was a significant predictor of rehospitalization for HF (hazard ratio 1.50; 95% confidence interval 1.07–2.13; P = 0.021). Conclusions Worsening of both independence and difficulties in ADL was triggered by hospitalization in older HF patients, and difficulties in ADL were relevant factors for risk of rehospitalization regardless of independence in ADL. These findings indicate the importance of preventing not only decreased independence but also increased difficulties in ADL during and after hospitalization. [ABSTRACT FROM AUTHOR]

Published
2023
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9. Relevant factors of leg strength at hospital discharge in patients hospitalized due to acute decompensated heart failure: multi-institutional prospective observational study

Author

Nemoto, Shinji, primary, Kasahara, Yusuke, additional, Izawa, Kazuhiro P, additional, Watanabe, Satoshi, additional, Yoshizawa, Kazuya, additional, Takeichi, Naoya, additional, Akao, Keigo, additional, Watanabe, Sato, additional, Mizukoshi, Kei, additional, Suzuki, Norio, additional, Ashikaga, Kohei, additional, Kida, Keisuke, additional, Osada, Naohiko, additional, and Akashi, Yoshihiro J, additional

Published
2022
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22. Heart-Rate Response to Sympathetic Nervous Stimulation, Exercise, and Magnesium Concentration in Various Sleep Conditions.

Author

Omiya, Kazuto, Akashi, Yoshihiro J., Yoneyama, Kihei, Osada, Naohiko, Tanabe, Kazuhiko, and Miyake, Fumihiko

Subjects
SLEEP deprivation, MAGNESIUM in the body, EXERCISE tests, HEART rate monitoring, CARDIOVASCULAR fitness, SYMPATHETIC nervous system, PHYSICAL fitness
Abstract

The aim of this study was to clarify the mechanism of impaired exercise tolerance in chronic sleep-restricted conditions by investigating variables related to heart-rate (HR) response to sympathetic nervous stimulation. Sixteen healthy men (mean age 21.5 years) were tested in a control state, acute sleep-loss state, and chronic sleeprestricted state. Participants underwent cardiopulmonary exercise testing in each state. Their norepinephrine (NE) concentration was measured before and immediately after exercise. Intracellular magnesium (Mg) concentration was measured in a resting state. Exercise duration was shorter and the ratio of HR response to the percentage increase in NE was higher in the chronic sleep-restricted state than in the control state. Intracellular Mg gradually decreased from control to chronic sleep restriction. There was a negative correlation between peak exercise duration and the ratios of HR response to the rate of increase in NE. Intracellular Mg was positively correlated with the ratios of HR response to the increase in NE both in control and in acute sleep loss. The authors conclude that the impaired exercise tolerance in a chronic sleep-restricted state is caused by hypersensitivity of the HR response to sympathetic nervous stimulation, which showed a compensation for decreased intracellular Mg concentration. [ABSTRACT FROM AUTHOR]

Published
2009
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26. Prevalence of Exercise-induced Bronchoconstriction in Japanese Medical Students

Author

Uchino, Aya, primary, Fujiya, Hiroto, additional, Yui, Naoko, additional, Tateishi, Keisuke, additional, Yatabe, Kanaka, additional, Terawaki, Fumiko, additional, Yoshioka, Hirotaka, additional, Terauchi, Koh, additional, Ohno, Mahiro, additional, Kudo, Takaaki, additional, Kobayashi, Hajime, additional, Osada, Naohiko, additional, Matsumoto, Naoki, additional, and Musha, Haruki, additional

Published
2017
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29. Gender-related Differences in Maximum Gait Speed and Daily Physical Activity in Elderly Hospitalized Cardiac Inpatients

Author

Izawa, Kazuhiro P., Watanabe, Satoshi, Hirano, Yasuyuki, Matsushima, Shinya, Suzuki, Tomohiro, Oka, Koichiro, Kida, Keisuke, Suzuki, Kengo, Osada, Naohiko, Omiya, Kazuto, Brubaker, Peter H., Shimizu, Hiroyuki, and Akashi, Yoshihiro J.

Subjects
Aged, 80 and over, Male, Inpatients, Sex Characteristics, Heart Diseases, Observational Study, Length of Stay, Article, Cross-Sectional Studies, Japan, Humans, Female, Exercise, Gait, Aged
Abstract

Maximum gait speed and physical activity (PA) relate to mortality and morbidity, but little is known about gender-related differences in these factors in elderly hospitalized cardiac inpatients. This study aimed to determine differences in maximum gait speed and daily measured PA based on sex and the relationship between these measures in elderly cardiac inpatients. A consecutive 268 elderly Japanese cardiac inpatients (mean age, 73.3 years) were enrolled and divided by sex into female (n = 75, 28%) and male (n = 193, 72%) groups. Patient characteristics and maximum gait speed, average step count, and PA energy expenditure (PAEE) in kilocalorie per day for 2 days assessed by accelerometer were compared between groups. Gait speed correlated positively with in-hospital PA measured by average daily step count (r = 0.46, P

Published
2015

31. Impaired β-cell function attenuates training effects by reducing the increase in heart rate reserve in patients with myocardial infarction

Author

Omiya, Kazuto, primary, Minami, Keisuke, additional, Sato, Yukio, additional, Takai, Manabu, additional, Takahashi, Eiji, additional, Hayashi, Akio, additional, Yamauchi, Masahiro, additional, Suzuki, Kengo, additional, Akashi, Yoshihiro J., additional, Osada, Naohiko, additional, Izawa, Kazuhiro P., additional, and Watanabe, Satoshi, additional

Published
2015
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33. Relation Between V˙E/V˙CO2 Slope and Maximum Phonation Time in Chronic Heart Failure Patients

Author

Izawa, Kazuhiro P., primary, Watanabe, Satoshi, additional, Brubaker, Peter H., additional, Tochimoto, Shinobu, additional, Hirano, Yasuyuki, additional, Matsushima, Shinya, additional, Suzuki, Tomohiro, additional, Oka, Koichiro, additional, Saito, Takashi, additional, Omori, Yutaka, additional, Suzuki, Kengo, additional, Osada, Naohiko, additional, Omiya, Kazuto, additional, Shimizu, Hiroyuki, additional, and Akashi, Yoshihiro J., additional

Published
2014
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34. The relation between Geriatric Nutritional Risk Index and muscle mass, muscle strength, and exercise capacity in chronic heart failure patients

Author

Izawa, Kazuhiro P., primary, Watanabe, Satoshi, additional, Hirano, Yasuyuki, additional, Yamamoto, Shuhei, additional, Oka, Koichiro, additional, Suzuki, Norio, additional, Kida, Keisuke, additional, Suzuki, Kengo, additional, Osada, Naohiko, additional, Omiya, Kazuto, additional, Brubaker, Peter H., additional, Shimizu, Hiroyuki, additional, and Akashi, Yoshihiro J., additional

Published
2014
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35. Differences in physical performance based on the Geriatric Nutritional Risk Index in elderly female cardiac patients

Author

Izawa, Kazuhiro P., primary, Watanabe, Satoshi, additional, Oka, Koichiro, additional, Mogamiya, Takuma, additional, Tada, Mika, additional, Nakata, Shuichi, additional, Nitobe, Sato, additional, Yoshizawa, Kazuya, additional, Hirano, Yasuyuki, additional, Osada, Naohiko, additional, Omiya, Kazuto, additional, and Shimizu, Hiroyuki, additional

Published
2014
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44. Early diastolic function during exertion influences exercise intolerance in patients with hypertrophic cardiomyopathy

Author

Mizukoshi, Kei, primary, Suzuki, Kengo, additional, Yoneyama, Kihei, additional, Kamijima, Ryo, additional, Kou, Seisyou, additional, Takai, Manabu, additional, Izumo, Masaki, additional, Hayashi, Akio, additional, Ohtaki, Eiji, additional, Akashi, Yoshihiro J., additional, Osada, Naohiko, additional, Omiya, Kazuto, additional, Harada, Tomoo, additional, Nobuoka, Sachihiko, additional, and Miyake, Fumihiko, additional

Published
2012
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