Author: "Ortega, Gemma" - Searchworks@Jio Institute Digital Library Search Results

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282 results on '"Ortega, Gemma"'

1. Cyclosporine A in hospitalized COVID-19 pneumonia patients to prevent the development of interstitial lung disease: a pilot randomized clinical trial

Author: Cobo-Ibáñez, Tatiana, Mora Ortega, Gemma, Sánchez-Piedra, Carlos, Serralta-San Martín, Gonzalo, Thuissard-Vasallo, Israel J., Lores Gutiérrez, Vanesa, Soler Rangel, Llanos, García Yubero, Cristina, Esteban-Vázquez, Ana, López-Aspiroz, Elena, Andreu Vázquez, Cristina, Toboso, Inmaculada, Martínez Alonso de Armiño, Blanca María, Olivares Alviso, Rocío Alejandra, Calderón Nieto, Rocío, Yañez, Cecilia, Zakhour González, Marlín Alejandra, Sainz Sánchez, Tatiana, Arroyo de la Torre, Silvia, Del Amo Del Arco, Nazaret, Gómez-Cerezo, Jorge Francisco, Ramírez Prieto, Teresa, Martínez Hernández, Alicia, and Muñoz-Fernández, Santiago
Published: 2024
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2. Unveiling the sound of the cognitive status: Machine Learning-based speech analysis in the Alzheimer’s disease spectrum

Author: García-Gutiérrez, Fernando, Alegret, Montserrat, Marquié, Marta, Muñoz, Nathalia, Ortega, Gemma, Cano, Amanda, De Rojas, Itziar, García-González, Pablo, Olivé, Clàudia, Puerta, Raquel, García-Sanchez, Ainhoa, Capdevila-Bayo, María, Montrreal, Laura, Pytel, Vanesa, Rosende-Roca, Maitee, Zaldua, Carla, Gabirondo, Peru, Tárraga, Lluís, Ruiz, Agustín, Boada, Mercè, and Valero, Sergi
Published: 2024
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3. Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

Author: de Rojas, Itziar, Moreno-Grau, Sonia, Tesi, Niccolo, Grenier-Boley, Benjamin, Andrade, Victor, Jansen, Iris E., Pedersen, Nancy L., Stringa, Najada, Zettergren, Anna, Hernández, Isabel, Montrreal, Laura, Antúnez, Carmen, Antonell, Anna, Tankard, Rick M., Bis, Joshua C., Sims, Rebecca, Bellenguez, Céline, Quintela, Inés, González-Perez, Antonio, Calero, Miguel, Franco-Macías, Emilio, Macías, Juan, Blesa, Rafael, Cervera-Carles, Laura, Menéndez-González, Manuel, Frank-García, Ana, Royo, Jose Luís, Moreno, Fermin, Huerto Vilas, Raquel, Baquero, Miquel, Diez-Fairen, Mónica, Lage, Carmen, García-Madrona, Sebastián, García-González, Pablo, Alarcón-Martín, Emilio, Valero, Sergi, Sotolongo-Grau, Oscar, Ullgren, Abbe, Naj, Adam C., Lemstra, Afina W., Benaque, Alba, Pérez-Cordón, Alba, Benussi, Alberto, Rábano, Alberto, Padovani, Alessandro, Squassina, Alessio, de Mendonça, Alexandre, Arias Pastor, Alfonso, Kok, Almar A. L., Meggy, Alun, Pastor, Ana Belén, Espinosa, Ana, Corma-Gómez, Anaïs, Martín Montes, Angel, Sanabria, Ángela, DeStefano, Anita L., Schneider, Anja, Haapasalo, Annakaisa, Kinhult Ståhlbom, Anne, Tybjærg-Hansen, Anne, Hartmann, Annette M., Spottke, Annika, Corbatón-Anchuelo, Arturo, Rongve, Arvid, Borroni, Barbara, Arosio, Beatrice, Nacmias, Benedetta, Nordestgaard, Børge G., Kunkle, Brian W., Charbonnier, Camille, Abdelnour, Carla, Masullo, Carlo, Martínez Rodríguez, Carmen, Muñoz-Fernandez, Carmen, Dufouil, Carole, Graff, Caroline, Ferreira, Catarina B., Chillotti, Caterina, Reynolds, Chandra A., Fenoglio, Chiara, Van Broeckhoven, Christine, Clark, Christopher, Pisanu, Claudia, Satizabal, Claudia L., Holmes, Clive, Buiza-Rueda, Dolores, Aarsland, Dag, Rujescu, Dan, Alcolea, Daniel, Galimberti, Daniela, Wallon, David, Seripa, Davide, Grünblatt, Edna, Dardiotis, Efthimios, Düzel, Emrah, Scarpini, Elio, Conti, Elisa, Rubino, Elisa, Gelpi, Ellen, Rodriguez-Rodriguez, Eloy, Duron, Emmanuelle, Boerwinkle, Eric, Ferri, Evelyn, Tagliavini, Fabrizio, Küçükali, Fahri, Pasquier, Florence, Sanchez-Garcia, Florentino, Mangialasche, Francesca, Jessen, Frank, Nicolas, Gaël, Selbæk, Geir, Ortega, Gemma, Chêne, Geneviève, Hadjigeorgiou, Georgios, Rossi, Giacomina, Spalletta, Gianfranco, Giaccone, Giorgio, Grande, Giulia, Binetti, Giuliano, Papenberg, Goran, Hampel, Harald, Bailly, Henri, Zetterberg, Henrik, Soininen, Hilkka, Karlsson, Ida K., Alvarez, Ignacio, Appollonio, Ildebrando, Giegling, Ina, Skoog, Ingmar, Saltvedt, Ingvild, Rainero, Innocenzo, Rosas Allende, Irene, Hort, Jakub, Diehl-Schmid, Janine, Van Dongen, Jasper, Vidal, Jean-Sebastien, Lehtisalo, Jenni, Wiltfang, Jens, Thomassen, Jesper Qvist, Kornhuber, Johannes, Haines, Jonathan L., Vogelgsang, Jonathan, Pineda, Juan A., Fortea, Juan, Popp, Julius, Deckert, Jürgen, Buerger, Katharina, Morgan, Kevin, Fließbach, Klaus, Sleegers, Kristel, Molina-Porcel, Laura, Kilander, Lena, Weinhold, Leonie, Farrer, Lindsay A., Wang, Li-San, Kleineidam, Luca, Farotti, Lucia, Parnetti, Lucilla, Tremolizzo, Lucio, Hausner, Lucrezia, Benussi, Luisa, Froelich, Lutz, Ikram, M. Arfan, Deniz-Naranjo, M. Candida, Tsolaki, Magda, Rosende-Roca, Maitée, Löwenmark, Malin, Hulsman, Marc, Spallazzi, Marco, Pericak-Vance, Margaret A., Esiri, Margaret, Bernal Sánchez-Arjona, María, Dalmasso, Maria Carolina, Martínez-Larrad, María Teresa, Arcaro, Marina, Nöthen, Markus M., Fernández-Fuertes, Marta, Dichgans, Martin, Ingelsson, Martin, Herrmann, Martin J., Scherer, Martin, Vyhnalek, Martin, Kosmidis, Mary H., Yannakoulia, Mary, Schmid, Matthias, Ewers, Michael, Heneka, Michael T., Wagner, Michael, Scamosci, Michela, Kivipelto, Miia, Hiltunen, Mikko, Zulaica, Miren, Alegret, Montserrat, Fornage, Myriam, Roberto, Natalia, van Schoor, Natasja M., Seidu, Nazib M., Banaj, Nerisa, Armstrong, Nicola J., Scarmeas, Nikolaos, Scherbaum, Norbert, Goldhardt, Oliver, Hanon, Oliver, Peters, Oliver, Skrobot, Olivia Anna, Quenez, Olivier, Lerch, Ondrej, Bossù, Paola, Caffarra, Paolo, Dionigi Rossi, Paolo, Sakka, Paraskevi, Mecocci, Patrizia, Hoffmann, Per, Holmans, Peter A., Fischer, Peter, Riederer, Peter, Yang, Qiong, Marshall, Rachel, Kalaria, Rajesh N., Mayeux, Richard, Vandenberghe, Rik, Cecchetti, Roberta, Ghidoni, Roberta, Frikke-Schmidt, Ruth, Sorbi, Sandro, Hägg, Sara, Engelborghs, Sebastiaan, Helisalmi, Seppo, Botne Sando, Sigrid, Kern, Silke, Archetti, Silvana, Boschi, Silvia, Fostinelli, Silvia, Gil, Silvia, Mendoza, Silvia, Mead, Simon, Ciccone, Simona, Djurovic, Srdjan, Heilmann-Heimbach, Stefanie, Riedel-Heller, Steffi, Kuulasmaa, Teemu, del Ser, Teodoro, Lebouvier, Thibaud, Polak, Thomas, Ngandu, Tiia, Grimmer, Timo, Bessi, Valentina, Escott-Price, Valentina, Giedraitis, Vilmantas, Deramecourt, Vincent, Maier, Wolfgang, Jian, Xueqiu, Pijnenburg, Yolande A. L., Kehoe, Patrick Gavin, Garcia-Ribas, Guillermo, Sánchez-Juan, Pascual, Pastor, Pau, Pérez-Tur, Jordi, Piñol-Ripoll, Gerard, Lopez de Munain, Adolfo, García-Alberca, Jose María, Bullido, María J., Álvarez, Victoria, Lleó, Alberto, Real, Luis M., Mir, Pablo, Medina, Miguel, Scheltens, Philip, Holstege, Henne, Marquié, Marta, Sáez, María Eugenia, Carracedo, Ángel, Amouyel, Philippe, Schellenberg, Gerard D., Williams, Julie, Seshadri, Sudha, van Duijn, Cornelia M., Mather, Karen A., Sánchez-Valle, Raquel, Serrano-Ríos, Manuel, Orellana, Adelina, Tárraga, Lluís, Blennow, Kaj, Huisman, Martijn, Andreassen, Ole A., Posthuma, Danielle, Clarimón, Jordi, Boada, Mercè, van der Flier, Wiesje M., Ramirez, Alfredo, Lambert, Jean-Charles, van der Lee, Sven J., and Ruiz, Agustín
Published: 2023
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4. A randomized, open-label clinical trial in mild cognitive impairment with EGb 761 examining blood markers of inflammation and oxidative stress

Author: Morató, Xavier, Marquié, Marta, Tartari, Juan Pablo, Lafuente, Asunción, Abdelnour, Carla, Alegret, Montserrat, Jofresa, Sara, Buendía, Mar, Pancho, Ana, Aguilera, Núria, Ibarria, Marta, Diego, Susana, Cuevas, Rosario, Cañada, Laia, Calvet, Anna, Antonio, Ester Esteban-De, Pérez-Cordón, Alba, Sanabria, Ángela, de Rojas, Itziar, Nuñez-Llaves, Raúl, Cano, Amanda, Orellana, Adelina, Montrreal, Laura, Cañabate, Pilar, Rosende-Roca, Maitée, Vargas, Liliana, Bojaryn, Urszula, Ricciardi, Mario, Ariton, Diana M., Espinosa, Ana, Ortega, Gemma, Muñoz, Nathalia, Lleonart, Núria, Alarcón-Martín, Emilio, Moreno, Mariola, Preckler, Silvia, Tantinya, Natalia, Ramis, Maribel, Nogales, Ana Belen, Seguer, Susanna, Martín, Elvira, Pytel, Vanesa, Valero, Sergi, Gurruchaga, Miren, Tárraga, Lluís, Ruiz, Agustín, and Boada, Mercè
Published: 2023
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5. New insights into the genetic etiology of Alzheimer’s disease and related dementias

Author: Bellenguez, Céline, Küçükali, Fahri, Jansen, Iris E., Kleineidam, Luca, Moreno-Grau, Sonia, Amin, Najaf, Naj, Adam C., Campos-Martin, Rafael, Grenier-Boley, Benjamin, Andrade, Victor, Holmans, Peter A., Boland, Anne, Damotte, Vincent, van der Lee, Sven J., Costa, Marcos R., Kuulasmaa, Teemu, Yang, Qiong, de Rojas, Itziar, Bis, Joshua C., Yaqub, Amber, Prokic, Ivana, Chapuis, Julien, Ahmad, Shahzad, Giedraitis, Vilmantas, Aarsland, Dag, Garcia-Gonzalez, Pablo, Abdelnour, Carla, Alarcón-Martín, Emilio, Alcolea, Daniel, Alegret, Montserrat, Alvarez, Ignacio, Álvarez, Victoria, Armstrong, Nicola J., Tsolaki, Anthoula, Antúnez, Carmen, Appollonio, Ildebrando, Arcaro, Marina, Archetti, Silvana, Pastor, Alfonso Arias, Arosio, Beatrice, Athanasiu, Lavinia, Bailly, Henri, Banaj, Nerisa, Baquero, Miquel, Barral, Sandra, Beiser, Alexa, Pastor, Ana Belén, Below, Jennifer E., Benchek, Penelope, Benussi, Luisa, Berr, Claudine, Besse, Céline, Bessi, Valentina, Binetti, Giuliano, Bizarro, Alessandra, Blesa, Rafael, Boada, Mercè, Boerwinkle, Eric, Borroni, Barbara, Boschi, Silvia, Bossù, Paola, Bråthen, Geir, Bressler, Jan, Bresner, Catherine, Brodaty, Henry, Brookes, Keeley J., Brusco, Luis Ignacio, Buiza-Rueda, Dolores, Bûrger, Katharina, Burholt, Vanessa, Bush, William S., Calero, Miguel, Cantwell, Laura B., Chene, Geneviève, Chung, Jaeyoon, Cuccaro, Michael L., Carracedo, Ángel, Cecchetti, Roberta, Cervera-Carles, Laura, Charbonnier, Camille, Chen, Hung-Hsin, Chillotti, Caterina, Ciccone, Simona, Claassen, Jurgen A. H. R., Clark, Christopher, Conti, Elisa, Corma-Gómez, Anaïs, Costantini, Emanuele, Custodero, Carlo, Daian, Delphine, Dalmasso, Maria Carolina, Daniele, Antonio, Dardiotis, Efthimios, Dartigues, Jean-François, de Deyn, Peter Paul, de Paiva Lopes, Katia, de Witte, Lot D., Debette, Stéphanie, Deckert, Jürgen, del Ser, Teodoro, Denning, Nicola, DeStefano, Anita, Dichgans, Martin, Diehl-Schmid, Janine, Diez-Fairen, Mónica, Rossi, Paolo Dionigi, Djurovic, Srdjan, Duron, Emmanuelle, Düzel, Emrah, Dufouil, Carole, Eiriksdottir, Gudny, Engelborghs, Sebastiaan, Escott-Price, Valentina, Espinosa, Ana, Ewers, Michael, Faber, Kelley M., Fabrizio, Tagliavini, Nielsen, Sune Fallgaard, Fardo, David W., Farotti, Lucia, Fenoglio, Chiara, Fernández-Fuertes, Marta, Ferrari, Raffaele, Ferreira, Catarina B., Ferri, Evelyn, Fin, Bertrand, Fischer, Peter, Fladby, Tormod, Fließbach, Klaus, Fongang, Bernard, Fornage, Myriam, Fortea, Juan, Foroud, Tatiana M., Fostinelli, Silvia, Fox, Nick C., Franco-Macías, Emlio, Bullido, María J., Frank-García, Ana, Froelich, Lutz, Fulton-Howard, Brian, Galimberti, Daniela, García-Alberca, Jose Maria, García-González, Pablo, Garcia-Madrona, Sebastian, Garcia-Ribas, Guillermo, Ghidoni, Roberta, Giegling, Ina, Giorgio, Giaccone, Goate, Alison M., Goldhardt, Oliver, Gomez-Fonseca, Duber, González-Pérez, Antonio, Graff, Caroline, Grande, Giulia, Green, Emma, Grimmer, Timo, Grünblatt, Edna, Grunin, Michelle, Gudnason, Vilmundur, Guetta-Baranes, Tamar, Haapasalo, Annakaisa, Hadjigeorgiou, Georgios, Haines, Jonathan L., Hamilton-Nelson, Kara L., Hampel, Harald, Hanon, Olivier, Hardy, John, Hartmann, Annette M., Hausner, Lucrezia, Harwood, Janet, Heilmann-Heimbach, Stefanie, Helisalmi, Seppo, Heneka, Michael T., Hernández, Isabel, Herrmann, Martin J., Hoffmann, Per, Holmes, Clive, Holstege, Henne, Vilas, Raquel Huerto, Hulsman, Marc, Humphrey, Jack, Biessels, Geert Jan, Jian, Xueqiu, Johansson, Charlotte, Jun, Gyungah R., Kastumata, Yuriko, Kauwe, John, Kehoe, Patrick G., Kilander, Lena, Ståhlbom, Anne Kinhult, Kivipelto, Miia, Koivisto, Anne, Kornhuber, Johannes, Kosmidis, Mary H., Kukull, Walter A., Kuksa, Pavel P., Kunkle, Brian W., Kuzma, Amanda B., Lage, Carmen, Laukka, Erika J., Launer, Lenore, Lauria, Alessandra, Lee, Chien-Yueh, Lehtisalo, Jenni, Lerch, Ondrej, Lleó, Alberto, Longstreth, Jr, William, Lopez, Oscar, de Munain, Adolfo Lopez, Love, Seth, Löwemark, Malin, Luckcuck, Lauren, Lunetta, Kathryn L., Ma, Yiyi, Macías, Juan, MacLeod, Catherine A., Maier, Wolfgang, Mangialasche, Francesca, Spallazzi, Marco, Marquié, Marta, Marshall, Rachel, Martin, Eden R., Montes, Angel Martín, Rodríguez, Carmen Martínez, Masullo, Carlo, Mayeux, Richard, Mead, Simon, Mecocci, Patrizia, Medina, Miguel, Meggy, Alun, Mehrabian, Shima, Mendoza, Silvia, Menéndez-González, Manuel, Mir, Pablo, Moebus, Susanne, Mol, Merel, Molina-Porcel, Laura, Montrreal, Laura, Morelli, Laura, Moreno, Fermin, Morgan, Kevin, Mosley, Thomas, Nöthen, Markus M., Muchnik, Carolina, Mukherjee, Shubhabrata, Nacmias, Benedetta, Ngandu, Tiia, Nicolas, Gael, Nordestgaard, Børge G., Olaso, Robert, Orellana, Adelina, Orsini, Michela, Ortega, Gemma, Padovani, Alessandro, Paolo, Caffarra, Papenberg, Goran, Parnetti, Lucilla, Pasquier, Florence, Pastor, Pau, Peloso, Gina, Pérez-Cordón, Alba, Pérez-Tur, Jordi, Pericard, Pierre, Peters, Oliver, Pijnenburg, Yolande A. L., Pineda, Juan A., Piñol-Ripoll, Gerard, Pisanu, Claudia, Polak, Thomas, Popp, Julius, Posthuma, Danielle, Priller, Josef, Puerta, Raquel, Quenez, Olivier, Quintela, Inés, Thomassen, Jesper Qvist, Rábano, Alberto, Rainero, Innocenzo, Rajabli, Farid, Ramakers, Inez, Real, Luis M., Reinders, Marcel J. T., Reitz, Christiane, Reyes-Dumeyer, Dolly, Ridge, Perry, Riedel-Heller, Steffi, Riederer, Peter, Roberto, Natalia, Rodriguez-Rodriguez, Eloy, Rongve, Arvid, Allende, Irene Rosas, Rosende-Roca, Maitée, Royo, Jose Luis, Rubino, Elisa, Rujescu, Dan, Sáez, María Eugenia, Sakka, Paraskevi, Saltvedt, Ingvild, Sanabria, Ángela, Sánchez-Arjona, María Bernal, Sanchez-Garcia, Florentino, Juan, Pascual Sánchez, Sánchez-Valle, Raquel, Sando, Sigrid B., Sarnowski, Chloé, Satizabal, Claudia L., Scamosci, Michela, Scarmeas, Nikolaos, Scarpini, Elio, Scheltens, Philip, Scherbaum, Norbert, Scherer, Martin, Schmid, Matthias, Schneider, Anja, Schott, Jonathan M., Selbæk, Geir, Seripa, Davide, Serrano, Manuel, Sha, Jin, Shadrin, Alexey A., Skrobot, Olivia, Slifer, Susan, Snijders, Gijsje J. L., Soininen, Hilkka, Solfrizzi, Vincenzo, Solomon, Alina, Song, Yeunjoo, Sorbi, Sandro, Sotolongo-Grau, Oscar, Spalletta, Gianfranco, Spottke, Annika, Squassina, Alessio, Stordal, Eystein, Tartan, Juan Pablo, Tárraga, Lluís, Tesí, Niccolo, Thalamuthu, Anbupalam, Thomas, Tegos, Tosto, Giuseppe, Traykov, Latchezar, Tremolizzo, Lucio, Tybjærg-Hansen, Anne, Uitterlinden, Andre, Ullgren, Abbe, Ulstein, Ingun, Valero, Sergi, Valladares, Otto, Broeckhoven, Christine Van, Vance, Jeffery, Vardarajan, Badri N., van der Lugt, Aad, Dongen, Jasper Van, van Rooij, Jeroen, van Swieten, John, Vandenberghe, Rik, Verhey, Frans, Vidal, Jean-Sébastien, Vogelgsang, Jonathan, Vyhnalek, Martin, Wagner, Michael, Wallon, David, Wang, Li-San, Wang, Ruiqi, Weinhold, Leonie, Wiltfang, Jens, Windle, Gill, Woods, Bob, Yannakoulia, Mary, Zare, Habil, Zhao, Yi, Zhang, Xiaoling, Zhu, Congcong, Zulaica, Miren, Farrer, Lindsay A., Psaty, Bruce M., Ghanbari, Mohsen, Raj, Towfique, Sachdev, Perminder, Mather, Karen, Jessen, Frank, Ikram, M. Arfan, de Mendonça, Alexandre, Hort, Jakub, Tsolaki, Magda, Pericak-Vance, Margaret A., Amouyel, Philippe, Williams, Julie, Frikke-Schmidt, Ruth, Clarimon, Jordi, Deleuze, Jean-François, Rossi, Giacomina, Seshadri, Sudha, Andreassen, Ole A., Ingelsson, Martin, Hiltunen, Mikko, Sleegers, Kristel, Schellenberg, Gerard D., van Duijn, Cornelia M., Sims, Rebecca, van der Flier, Wiesje M., Ruiz, Agustín, Ramirez, Alfredo, and Lambert, Jean-Charles
Published: 2022
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6. Differences in macular vessel density in the superficial plexus across cognitive impairment: the NORFACE cohort

Author: Marquié, Marta, Valero, Sergi, Martínez, Joan, Alarcón-Martín, Emilio, García-Sánchez, Ainhoa, de Rojas, Itziar, Castilla-Martí, Miguel, Castilla-Martí, Luis, Hernández, Isabel, Rosende-Roca, Maitée, Vargas, Liliana, Tartari, Juan Pablo, Esteban-De Antonio, Ester, Bojaryn, Urszula, Pytel, Vanesa, Narvaiza, Leire, Alegret, Montserrat, Ortega, Gemma, Espinosa, Ana, Sanabria, Ángela, Pérez-Cordón, Alba, Lleonart, Núria, Muñoz, Nathalia, Tárraga, Lluís, Ruiz, Agustín, and Boada, Mercè
Published: 2022
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7. Automatized FACEmemory® scoring is related to Alzheimer’s disease phenotype and biomarkers in early-onset mild cognitive impairment: the BIOFACE cohort

Author: Alegret, Montserrat, Sotolongo-Grau, Oscar, de Antonio, Ester Esteban, Pérez-Cordón, Alba, Orellana, Adelina, Espinosa, Ana, Gil, Silvia, Jiménez, Daniel, Ortega, Gemma, Sanabria, Angela, Roberto, Natalia, Hernández, Isabel, Rosende-Roca, Maitee, Tartari, Juan Pablo, Alarcon-Martin, Emilio, de Rojas, Itziar, Montrreal, Laura, Morató, Xavier, Cano, Amanda, Rentz, Dorene M., Tárraga, Lluís, Ruiz, Agustín, Valero, Sergi, Marquié, Marta, and Boada, Mercè
Published: 2022
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8. FACEmemory®, an Innovative Online Platform for Episodic Memory Pre-Screening: Findings from the First 3,000 Participants

Author: Alegret, Montserrat, primary, García-Gutiérrez, Fernando, additional, Muñoz, Nathalia, additional, Espinosa, Ana, additional, Ortega, Gemma, additional, Lleonart, Núria, additional, Rodríguez, Isabel, additional, Rosende-Roca, Maitee, additional, Pytel, Vanesa, additional, Cantero-Fortiz, Yahveth, additional, Rentz, Dorene M., additional, Marquié, Marta, additional, Valero, Sergi, additional, Ruiz, Agustín, additional, Butler, Christopher, additional, and Boada, Mercè, additional
Published: 2024
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9. Cognitive improvement following endovascular embolization in patients with intracranial dural arteriovenous fistula: The Neuropsychology in dural ArterIal Fistula (NAIF) Study

Author: Gramegna, Laura Ludovica, primary, Ortega, Gemma, additional, Dinia, Lavinia, additional, Aixut, Sonia, additional, Rosati, Santiago, additional, Vega, Pedro, additional, Lüttich, Alex, additional, Remollo, Sebastian, additional, González, Alejandro, additional, Murias, Eduardo, additional, Chirife Chaparro, Oscar, additional, Moreu, Manuel, additional, Requena, Manuel, additional, de Dios Lascuevas, Marta, additional, Hernandez, David, additional, Quintana, Manuel, additional, Puig, Josep, additional, Rovira, Alex, additional, and Tomasello, Alejandro, additional
Published: 2023
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10. Predementia Counseling

Author: Schwegler, Carolin, primary, Schmitz-Luhn, Björn, additional, Romotzky, Vanessa, additional, Cañabate, Pilar, additional, Moreno, Mariola, additional, Ortega, Gemma, additional, Boada, Mercè, additional, Jessen, Frank, additional, Woopen, Christiane, additional, and Rostamzadeh, Ayda, additional
Published: 2023
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11. Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

Author: de Rojas, Itziar, Moreno-Grau, Sonia, Tesi, Niccolo, Grenier-Boley, Benjamin, Andrade, Victor, Jansen, Iris E., Pedersen, Nancy L., Stringa, Najada, Zettergren, Anna, Hernández, Isabel, Montrreal, Laura, Antúnez, Carmen, Antonell, Anna, Tankard, Rick M., Bis, Joshua C., Sims, Rebecca, Bellenguez, Céline, Quintela, Inés, González-Perez, Antonio, Calero, Miguel, Franco-Macías, Emilio, Macías, Juan, Blesa, Rafael, Cervera-Carles, Laura, Menéndez-González, Manuel, Frank-García, Ana, Royo, Jose Luís, Moreno, Fermin, Huerto Vilas, Raquel, Baquero, Miquel, Diez-Fairen, Mónica, Lage, Carmen, García-Madrona, Sebastián, García-González, Pablo, Alarcón-Martín, Emilio, Valero, Sergi, Sotolongo-Grau, Oscar, Ullgren, Abbe, Naj, Adam C., Lemstra, Afina W., Benaque, Alba, Pérez-Cordón, Alba, Benussi, Alberto, Rábano, Alberto, Padovani, Alessandro, Squassina, Alessio, de Mendonça, Alexandre, Arias Pastor, Alfonso, Kok, Almar A. L., Meggy, Alun, Pastor, Ana Belén, Espinosa, Ana, Corma-Gómez, Anaïs, Martín Montes, Angel, Sanabria, Ángela, DeStefano, Anita L., Schneider, Anja, Haapasalo, Annakaisa, Kinhult Ståhlbom, Anne, Tybjærg-Hansen, Anne, Hartmann, Annette M., Spottke, Annika, Corbatón-Anchuelo, Arturo, Rongve, Arvid, Borroni, Barbara, Arosio, Beatrice, Nacmias, Benedetta, Nordestgaard, Børge G., Kunkle, Brian W., Charbonnier, Camille, Abdelnour, Carla, Masullo, Carlo, Martínez Rodríguez, Carmen, Muñoz-Fernandez, Carmen, Dufouil, Carole, Graff, Caroline, Ferreira, Catarina B., Chillotti, Caterina, Reynolds, Chandra A., Fenoglio, Chiara, Van Broeckhoven, Christine, Clark, Christopher, Pisanu, Claudia, Satizabal, Claudia L., Holmes, Clive, Buiza-Rueda, Dolores, Aarsland, Dag, Rujescu, Dan, Alcolea, Daniel, Galimberti, Daniela, Wallon, David, Seripa, Davide, Grünblatt, Edna, Dardiotis, Efthimios, Düzel, Emrah, Scarpini, Elio, Conti, Elisa, Rubino, Elisa, Gelpi, Ellen, Rodriguez-Rodriguez, Eloy, Duron, Emmanuelle, Boerwinkle, Eric, Ferri, Evelyn, Tagliavini, Fabrizio, Küçükali, Fahri, Pasquier, Florence, Sanchez-Garcia, Florentino, Mangialasche, Francesca, Jessen, Frank, Nicolas, Gaël, Selbæk, Geir, Ortega, Gemma, Chêne, Geneviève, Hadjigeorgiou, Georgios, Rossi, Giacomina, Spalletta, Gianfranco, Giaccone, Giorgio, Grande, Giulia, Binetti, Giuliano, Papenberg, Goran, Hampel, Harald, Bailly, Henri, Zetterberg, Henrik, Soininen, Hilkka, Karlsson, Ida K., Alvarez, Ignacio, Appollonio, Ildebrando, Giegling, Ina, Skoog, Ingmar, Saltvedt, Ingvild, Rainero, Innocenzo, Rosas Allende, Irene, Hort, Jakub, Diehl-Schmid, Janine, Van Dongen, Jasper, Vidal, Jean-Sebastien, Lehtisalo, Jenni, Wiltfang, Jens, Thomassen, Jesper Qvist, Kornhuber, Johannes, Haines, Jonathan L., Vogelgsang, Jonathan, Pineda, Juan A., Fortea, Juan, Popp, Julius, Deckert, Jürgen, Buerger, Katharina, Morgan, Kevin, Fließbach, Klaus, Sleegers, Kristel, Molina-Porcel, Laura, Kilander, Lena, Weinhold, Leonie, Farrer, Lindsay A., Wang, Li-San, Kleineidam, Luca, Farotti, Lucia, Parnetti, Lucilla, Tremolizzo, Lucio, Hausner, Lucrezia, Benussi, Luisa, Froelich, Lutz, Ikram, M. Arfan, Deniz-Naranjo, M. Candida, Tsolaki, Magda, Rosende-Roca, Maitée, Löwenmark, Malin, Hulsman, Marc, Spallazzi, Marco, Pericak-Vance, Margaret A., Esiri, Margaret, Bernal Sánchez-Arjona, María, Dalmasso, Maria Carolina, Martínez-Larrad, María Teresa, Arcaro, Marina, Nöthen, Markus M., Fernández-Fuertes, Marta, Dichgans, Martin, Ingelsson, Martin, Herrmann, Martin J., Scherer, Martin, Vyhnalek, Martin, Kosmidis, Mary H., Yannakoulia, Mary, Schmid, Matthias, Ewers, Michael, Heneka, Michael T., Wagner, Michael, Scamosci, Michela, Kivipelto, Miia, Hiltunen, Mikko, Zulaica, Miren, Alegret, Montserrat, Fornage, Myriam, Roberto, Natalia, van Schoor, Natasja M., Seidu, Nazib M., Banaj, Nerisa, Armstrong, Nicola J., Scarmeas, Nikolaos, Scherbaum, Norbert, Goldhardt, Oliver, Hanon, Oliver, Peters, Oliver, Skrobot, Olivia Anna, Quenez, Olivier, Lerch, Ondrej, Bossù, Paola, Caffarra, Paolo, Dionigi Rossi, Paolo, Sakka, Paraskevi, Mecocci, Patrizia, Hoffmann, Per, Holmans, Peter A., Fischer, Peter, Riederer, Peter, Yang, Qiong, Marshall, Rachel, Kalaria, Rajesh N., Mayeux, Richard, Vandenberghe, Rik, Cecchetti, Roberta, Ghidoni, Roberta, Frikke-Schmidt, Ruth, Sorbi, Sandro, Hägg, Sara, Engelborghs, Sebastiaan, Helisalmi, Seppo, Botne Sando, Sigrid, Kern, Silke, Archetti, Silvana, Boschi, Silvia, Fostinelli, Silvia, Gil, Silvia, Mendoza, Silvia, Mead, Simon, Ciccone, Simona, Djurovic, Srdjan, Heilmann-Heimbach, Stefanie, Riedel-Heller, Steffi, Kuulasmaa, Teemu, del Ser, Teodoro, Lebouvier, Thibaud, Polak, Thomas, Ngandu, Tiia, Grimmer, Timo, Bessi, Valentina, Escott-Price, Valentina, Giedraitis, Vilmantas, Deramecourt, Vincent, Maier, Wolfgang, Jian, Xueqiu, Pijnenburg, Yolande A. L., Kehoe, Patrick Gavin, Garcia-Ribas, Guillermo, Sánchez-Juan, Pascual, Pastor, Pau, Pérez-Tur, Jordi, Piñol-Ripoll, Gerard, Lopez de Munain, Adolfo, García-Alberca, Jose María, Bullido, María J., Álvarez, Victoria, Lleó, Alberto, Real, Luis M., Mir, Pablo, Medina, Miguel, Scheltens, Philip, Holstege, Henne, Marquié, Marta, Sáez, María Eugenia, Carracedo, Ángel, Amouyel, Philippe, Schellenberg, Gerard D., Williams, Julie, Seshadri, Sudha, van Duijn, Cornelia M., Mather, Karen A., Sánchez-Valle, Raquel, Serrano-Ríos, Manuel, Orellana, Adelina, Tárraga, Lluís, Blennow, Kaj, Huisman, Martijn, Andreassen, Ole A., Posthuma, Danielle, Clarimón, Jordi, Boada, Mercè, van der Flier, Wiesje M., Ramirez, Alfredo, Lambert, Jean-Charles, van der Lee, Sven J., and Ruiz, Agustín
Published: 2021
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12. Author Correction: Interaction of neuropsychiatric symptoms with APOE ε4 and conversion to dementia in MCI patients in a Memory Clinic

Author: Valero, Sergi, Marquié, Marta, De Rojas, Itziar, Espinosa, Ana, Moreno‑Grau, Sonia, Orellana, Adelina, Montrreal, Laura, Hernández, Isabel, Mauleón, Ana, Rosende‑Roca, Maiteé, Alegret, Montse, Pérez‑Cordón, Alba, Ortega, Gemma, Roberto, Natalia, Sanabria, Angela, Abdelnour, Carla, Gil, Silvia, Tartari, Juan Pablo, Vargas, Liliana, Antonio, Ester Esteban‑De, Benaque, Alba, Tárraga, Lluís, Boada, Mercè, and Ruíz, Agustín
Published: 2021
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13. Neuropsychiatric profiles and conversion to dementia in mild cognitive impairment, a latent class analysis

Author: Roberto, Natalia, Portella, Maria J., Marquié, Marta, Alegret, Montserrat, Hernández, Isabel, Mauleón, Ana, Rosende-Roca, Maitee, Abdelnour, Carla, de Antonio, Ester Esteban, Gil, Silvia, Tartari, Juan P., Vargas, Liliana, Espinosa, Ana, Ortega, Gemma, Pérez-Cordón, Alba, Sanabria, Ángela, Orellana, Adelina, de Rojas, Itziar, Moreno-Grau, Sonia, Montrreal, Laura, Alarcón-Martín, Emilio, Ruíz, Agustín, Tárraga, Lluís, Boada, Mercè, and Valero, Sergi
Published: 2021
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14. Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project

Author: Abdelnour, C., Aguilera, N., Alarcon, E., Alegret, M., Benaque, A., Boada, M., Buendia, M., Cañabate, P., Carracedo, A., Corbatón, A., de Rojas, I., Diego, S., Espinosa, A., Gailhajenet, A., García González, P., Gil, S., Guitart, M., González Pérez, A., Hernández, I., Ibarria, M., Lafuente, A., Macias, J., Maroñas, O., Martín, E., Martínez, M.T., Marquié, M., Mauleón, A., Monté-Rubio, G., Montrreal, L., Moreno-Grau, S., Moreno, M., Orellana, A., Ortega, G., Pancho, A., Pelejà, E., Pérez-Cordon, A., Pineda, J.A., Preckler, S., Quintela, I., Real, L.M., Rodríguez-Gómez, O., Rosende-Roca, M., Ruiz, A., Ruiz, S., Sáez, M.E., Sanabria, A., Santos-Santos, M.A., Serrano-Rios, M., Sotolongo-Grau, O., Tárraga, L., Valero, S., Vargas, L., Adarmes-Gómez, A.D., Alarcón-Martín, E., Álvarez, I., Álvarez, V., Amer-Ferrer, Goo, Antequera, M., Antúnez, C., Baquero, M., Bernal, M., Blesa, R., Buiza-Rueda, D., Bullido, M.J., Burguera, J.A., Calero, M., Carrillo, F., Carrión-Claro, M., Casajeros, M.J., Clarimón, J., Cruz-Gamero, J.M., de Pancorbo, M.M., del Ser, T., Diez-Fairen, M., Fortea, J., Franco, E., Frank-García, A., García-Alberca, J.M., Garcia Madrona, S., Garcia-Ribas, G., Gómez-Garre, P., Hevilla, S., Jesús, S., Espinosa, Labrador, Lage, C., Legaz, A., Lleó, A., López de Munáin, A., López-García, S., Macias, D., Manzanares, S., Marín, M., Marín-Muñoz, J., Marín, T., Martín Montes, A., Martínez, B., Martínez, C., Martínez, V., Martínez-Lage Álvarez, P., Medina, M., Mendioroz Iriarte, M., Menéndez-González, M., Mir, P., Molinuevo, J.L., Pastor, A.B., Pastor, P., Pérez Tur, J., Periñán-Tocino, T., Piñol Ripoll, G., Rábano, A., Real de Asúa, D., Rodrigo, S., Rodríguez-Rodríguez, E., Royo, J.L., A, Ruiz, Sanchez del Valle Díaz, R., Sánchez-Juan, P., Sastre, I., Vicente, M.P., Vivancos, L., Moreno-Grau, Sonia, de Rojas, Itziar, Hernández, Isabel, Quintela, Inés, Montrreal, Laura, Alegret, Montserrat, Hernández-Olasagarre, Begoña, Madrid, Laura, González-Perez, Antonio, Maroñas, Olalla, Rosende-Roca, Maitée, Mauleón, Ana, Vargas, Liliana, Lafuente, Asunción, Abdelnour, Carla, Rodríguez-Gómez, Octavio, Gil, Silvia, Santos-Santos, Miguel Ángel, Espinosa, Ana, Ortega, Gemma, Sanabria, Ángela, Pérez-Cordón, Alba, Cañabate, Pilar, Moreno, Mariola, Preckler, Silvia, Ruiz, Susana, Aguilera, Nuria, Pineda, Juan Antonio, Macías, Juan, Alarcón-Martín, Emilio, Sotolongo-Grau, Oscar, Marquié, Marta, Monté-Rubio, Gemma, Valero, Sergi, Benaque, Alba, Clarimón, Jordi, Bullido, Maria Jesus, García-Ribas, Guillermo, Pástor, Pau, Sánchez-Juan, Pascual, Álvarez, Victoria, Piñol-Ripoll, Gerard, García-Alberca, Jose Maria, Royo, José Luis, Franco, Emilio, Mir, Pablo, Calero, Miguel, Medina, Miguel, Rábano, Alberto, Ávila, Jesús, Antúnez, Carmen, Real, Luis Miguel, Orellana, Adelina, Carracedo, Ángel, Sáez, María Eugenia, Tárraga, Lluís, Boada, Mercè, and Ruiz, Agustín
Published: 2019
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15. Exploring APOE genotype effects on Alzheimer's disease risk and amyloid β burden in individuals with subjective cognitive decline: The FundacioACE Healthy Brain Initiative (FACEHBI) study baseline results

Author: Abdelnour, C., Aguilera, N., Alegret, M., Berthier, M., Boada, M., Buendia, M., Bullich, S., Campos, F., Cañabate, P., Cuevas, C., de Rojas, I., Espinosa, A., Gailhajenet, A., Diego, S., Gil, S., Giménez, J., Gismondi, R., Gómez-Chiari, M., Guitart, M., Hernández-Olasagarre, B., Hernández, I., Ibarria, M., Lafuente, A., Lomeña, F., Martín, E., Martínez, J., Mauleón, A., Monté, G., Moreno, M., Moreno-Grau, S., Núñez, L., Orellana, A., Ortega, G., Páez, A., Pancho, A., Pavía, J., Pelejà, E., Pérez-Cordon, A., Pérez-Grijalba, V., Pesini, P., Preckler, S., Rodríguez-Gómez, O., Romero, J., Rosende-Roca, M., Ruiz, A., Ruiz, S., Sanabria, A., Sánchez-Ruiz, D., Santos-Santos, M.A., Sarasa, M., Sotolongo-Grau, O., Tárraga, L., Tejero, M.A., Torres, M., Valero, S., Vargas, L., Vivas, A., Moreno–Grau, Sonia, Rodríguez-Gómez, Octavio, Sanabria, Ángela, Pérez-Cordón, Alba, Sánchez-Ruiz, Domingo, Abdelnour, Carla, Valero, Sergi, Hernández, Isabel, Rosende-Roca, Maitée, Mauleón, Ana, Vargas, Liliana, Lafuente, Asunción, Gil, Silvia, Santos-Santos, Miguel Ángel, Alegret, Montserrat, Espinosa, Ana, Ortega, Gemma, Guitart, Marina, Gailhajanet, Anna, de Rojas, Itziar, Sotolongo-Grau, Óscar, Ruiz, Susana, Aguilera, Nuria, Papasey, Judith, Martín, Elvira, Peleja, Esther, Lomeña, Francisco, Campos, Francisco, Vivas, Assumpta, Gómez-Chiari, Marta, Tejero, Miguel Ángel, Giménez, Joan, Serrano-Ríos, Manuel, Orellana, Adelina, Tárraga, Lluís, Ruiz, Agustín, and Boada, Mercè
Published: 2018
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16. Interaction of neuropsychiatric symptoms with APOE ε4 and conversion to dementia in MCI patients in a Memory Clinic

Author: Valero, Sergi, Marquié, Marta, De Rojas, Itziar, Espinosa, Ana, Moreno-Grau, Sonia, Orellana, Adelina, Montrreal, Laura, Hernández, Isabel, Mauleón, Ana, Rosende-Roca, Maitée, Alegret, Montse, Pérez-Cordón, Alba, Ortega, Gemma, Roberto, Natalia, Sanabria, Angela, Abdelnour, Carla, Gil, Silvia, Tartari, Juan Pablo, Vargas, Liliana, Esteban-De Antonio, Ester, Benaque, Alba, Tárraga, Lluís, Boada, Mercè, and Ruíz, Agustín
Published: 2020
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17. FACEmemory®, an innovative online platform for episodic memory pre-screening: findings from the first 3,000 participants

Author: Alegret, Montserrat, primary, García-Gutiérrez, Fernando, additional, Muñoz, Nathalia, additional, Espinosa, Ana, additional, Ortega, Gemma, additional, Lleonart, Núria, additional, Rodríguez, Isabel, additional, Rosende-Roca, Maitee, additional, Pytel, Vanesa, additional, Cantero-Fortiz, Yahveth, additional, Rentz, Dorene M., additional, Marquié, Marta, additional, Valero, Sergi, additional, Ruiz, Agustin, additional, Butler, Christopher, additional, and Boada, Mercè, additional
Published: 2023
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18. A computerized version of the Short Form of the Face-Name Associative Memory Exam (FACEmemory®) for the early detection of Alzheimer’s disease

Author: Alegret, Montserrat, Muñoz, Nathalia, Roberto, Natalia, Rentz, Dorene M., Valero, Sergi, Gil, Silvia, Marquié, Marta, Hernández, Isabel, Riveros, Catalina, Sanabria, Angela, Perez-Cordon, Alba, Espinosa, Ana, Ortega, Gemma, Mauleón, Ana, Abdelnour, Carla, Rosende-Roca, Maitee, Papp, Kathryn V., Orellana, Adela, Benaque, Alba, Tarraga, Lluís, Ruiz, Agustín, and Boada, Mercè
Published: 2020
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19. Evaluation of macular thickness and volume tested by optical coherence tomography as biomarkers for Alzheimer’s disease in a memory clinic

Author: Sánchez, Domingo, Castilla-Marti, Miguel, Marquié, Marta, Valero, Sergi, Moreno-Grau, Sonia, Rodríguez-Gómez, Octavio, Piferrer, Albert, Martínez, Gabriel, Martínez, Joan, Rojas, Itziar De, Hernández, Isabel, Abdelnour, Carla, Rosende-Roca, Maitée, Vargas, Liliana, Mauleón, Ana, Gil, Silvia, Alegret, Montserrat, Ortega, Gemma, Espinosa, Ana, Pérez-Cordón, Alba, Sanabria, Ángela, Roberto, Natalia, Ciudin, Andreea, Simó, Rafael, Hernández, Cristina, Tárraga, Lluís, Boada, Mercè, and Ruiz, Agustín
Published: 2020
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20. Author Correction: Usefulness of peripapillary nerve fiber layer thickness assessed by optical coherence tomography as a biomarker for Alzheimer’s disease

Author: Sánchez, Domingo, Castilla-Marti, Miguel, Rodríguez-Gómez, Octavio, Valero, Sergi, Piferrer, Albert, Martínez, Gabriel, Martínez, Joan, Serra, Judit, Moreno-Grau, Sonia, Hernández-Olasagarre, Begoña, De Rojas, Itziar, Hernández, Isabel, Abdelnour, Carla, Rosende-Roca, Maitée, Vargas, Liliana, Mauleón, Ana, Santos-Santos, Miguel A., Alegret, Montserrat, Ortega, Gemma, Espinosa, Ana, Pérez-Cordón, Alba, Sanabria, Ángela, Ciudin, Andrea, Simó, Rafael, Hernández, Cristina, Villoslada, Pablo, Ruiz, Agustín, Tàrraga, Lluís, and Boada, Mercè
Published: 2019
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21. Macular vessel density in the superficial plexus is not associated to cerebrospinal fluid core biomarkers for Alzheimer’s disease in individuals with mild cognitive impairment: The NORFACE cohort

Author: Marquié, Marta, primary, García-Sánchez, Ainhoa, additional, Alarcón-Martín, Emilio, additional, Martínez, Joan, additional, Castilla-Martí, Miguel, additional, Castilla-Martí, Luis, additional, Orellana, Adelina, additional, Montrreal, Laura, additional, de Rojas, Itziar, additional, García-González, Pablo, additional, Puerta, Raquel, additional, Olivé, Clàudia, additional, Cano, Amanda, additional, Hernández, Isabel, additional, Rosende-Roca, Maitée, additional, Vargas, Liliana, additional, Tartari, Juan Pablo, additional, Esteban-De Antonio, Ester, additional, Bojaryn, Urszula, additional, Ricciardi, Mario, additional, Ariton, Diana M., additional, Pytel, Vanesa, additional, Alegret, Montserrat, additional, Ortega, Gemma, additional, Espinosa, Ana, additional, Pérez-Cordón, Alba, additional, Sanabria, Ángela, additional, Muñoz, Nathalia, additional, Lleonart, Núria, additional, Aguilera, Núria, additional, Tárraga, Lluís, additional, Valero, Sergi, additional, Ruiz, Agustín, additional, and Boada, Mercè, additional
Published: 2023
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22. Diagnostic value of respiratory polygraphy in patients with low probability of obstructive sleep apnea syndrome

Author: Hernandez Voth, Ana, Mora Ortega, Gemma, Moreno Zabaleta, Raul, Montoro Zulueta, Javier, Verdugo Cartas, Maria I., Rojo Moreno-Arrones, Blas, Lores Gutierrez, Vanesa, and Ramirez Prieto, María T.
Published: 2016
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23. Visual impairment in aging and cognitive decline: experience in a Memory Clinic

Author: Marquié, Marta, Castilla-Martí, Miguel, Valero, Sergi, Martínez, Joan, Sánchez, Domingo, Hernández, Isabel, Rosende-Roca, Maitée, Vargas, Liliana, Mauleón, Ana, Rodríguez-Gómez, Octavio, Abdelnour, Carla, Gil, Silvia, Santos-Santos, Miguel A., Alegret, Montserrat, Espinosa, Ana, Ortega, Gemma, Pérez-Cordón, Alba, Sanabria, Ángela, Roberto, Natalia, Moreno-Grau, Sonia, de Rojas, Itziar, Simó, Rafael, Ciudin, Andreea, Hernández, Cristina, Orellana, Adelina, Monté-Rubio, Gemma, Benaque, Alba, Ruiz, Agustín, Tárraga, Lluís, and Boada, Mercè
Published: 2019
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24. Predementia Counseling: Informed Decision-Making and Postcounseling Reflection.

Author: Schwegler, Carolin, Schmitz-Luhn, Björn, Romotzky, Vanessa, Cañabate, Pilar, Moreno, Mariola, Ortega, Gemma, Boada, Mercè, Jessen, Frank, Woopen, Christiane, and Rostamzadeh, Ayda
Published: 2023
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25. The Synergic Effect of AT(N) Profiles and Depression on the Risk of Conversion to Dementia in Patients with Mild Cognitive Impairment

Author: Marquié, Marta, primary, García-Gutiérrez, Fernando, additional, Orellana, Adelina, additional, Montrreal, Laura, additional, de Rojas, Itziar, additional, García-González, Pablo, additional, Puerta, Raquel, additional, Olivé, Clàudia, additional, Cano, Amanda, additional, Hernández, Isabel, additional, Rosende-Roca, Maitée, additional, Vargas, Liliana, additional, Tartari, Juan Pablo, additional, Esteban-De Antonio, Ester, additional, Bojaryn, Urszula, additional, Ricciardi, Mario, additional, Ariton, Diana M., additional, Pytel, Vanesa, additional, Alegret, Montserrat, additional, Ortega, Gemma, additional, Espinosa, Ana, additional, Pérez-Cordón, Alba, additional, Sanabria, Ángela, additional, Muñoz, Nathalia, additional, Lleonart, Núria, additional, Aguilera, Núria, additional, García-Sánchez, Ainhoa, additional, Alarcón-Martín, Emilio, additional, Tárraga, Lluís, additional, Ruiz, Agustín, additional, Boada, Mercè, additional, and Valero, Sergi, additional
Published: 2023
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26. Usefulness of peripapillary nerve fiber layer thickness assessed by optical coherence tomography as a biomarker for Alzheimer’s disease

Author: Sánchez, Domingo, Castilla-Marti, Miguel, Rodríguez-Gómez, Octavio, Valero, Sergi, Piferrer, Albert, Martínez, Gabriel, Martínez, Joan, Serra, Judit, Moreno-Grau, Sonia, Hernández-Olasagarre, Begoña, De Rojas, Itziar, Hernández, Isabel, Abdelnour, Carla, Rosende-Roca, Maitée, Vargas, Liliana, Mauleón, Ana, Santos-Santos, Miguel A., Alegret, Montserrat, Ortega, Gemma, Espinosa, Ana, Pérez-Cordón, Alba, Sanabria, Ángela, Ciudin, Andrea, Simó, Rafael, Hernández, Cristina, Villoslada, Pablo, Ruiz, Agustín, Tàrraga, Lluís, and Boada, Mercè
Published: 2018
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27. Predementia Counseling

Author: Schwegler, Carolin, Schmitz-Luhn, Björn, Romotzky, Vanessa, Cañabate, Pilar, Moreno, Mariola, Ortega, Gemma, Boada, Mercè, Jessen, Frank, Woopen, Christiane, and Rostamzadeh, Ayda
Subjects: ddc:150
Abstract: Improving risk prediction of Alzheimer’s dementia poses challenges to healthcare professionals, patients, and their social environment. Moreover, predictive diagnosis faces limited operationalized clinical recommendations. In this study, we developed manuals for counseling individuals with mild cognitive impairment on their biomarker-based dementia risk prediction; we interviewed 16 participants postcounseling. The interview analysis examines sources of knowledge concerning the decision regarding risk prediction. Subsequently, an interdisciplinary interpretation discusses implications for practice. By focusing on sources of the participants’ knowledge, we identified epistemic authorities, such as (former) medical-related professional background or previous disease experiences. The findings provide information on cues and conversational elements for improving counseling sessions. Sensibly integrated language-based and legal considerations may achieve a targeted and efficient joint decision-making process.
Published: 2023

28. Anger Assessment in Patients Treated With Brivaracetam

Author: Ortega, Gemma, Abraira, Laura, Martí, Glòria, Quintana, Manuel, Mazuela, Gonzalo, Santamarina, Estevo, Salas-Puig, Xavier, and Toledo, Manuel
Published: 2018
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29. Neurological damage after transcatheter aortic valve implantation compared with surgical aortic valve replacement in intermediate risk patients

Author: Abdul-Jawad Altisent, Omar, Ferreira-Gonzalez, Ignacio, Marsal, Josep R., Ribera, Aida, Auger, Cristina, Ortega, Gemma, Cascant, Purificación, Urena, Marina, Del Blanco, Bruno Garcia, Serra, Vicenç, Sureda, Carlos, Igual, Albert, Rovira, Alex, González-Alujas, María Teresa, Gonzalez, Anna, Puri, Rishi, Cuellar, Hug, Tornos, Pilar, Rodés-Cabau, Josep, and Garcia-Dorado, David
Published: 2016
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30. Abstract WP21: Cognitive Improvement In Patients With Dural Arterio-venous Fistula After Endovascular Embolization: Interim Analysis Of The NAIF Study

Author: Laura Gramegna, Ortega Gemma, Lavinia Dinia, Santiago Rosati, PEDRO VEGA, alejandro gonzalez, Alex Luttich, Sonia Aixut Lorenzo, Manuel Quintana, and alejandro tomasello
Subjects: Advanced and Specialized Nursing, Neurology (clinical), Cardiology and Cardiovascular Medicine
Abstract: Introduction: Dural arteriovenous fistulae (dAVF) are rare acquired intracranial vascular malformations with clinical manifestations varying from asymptomatic lesions, non-hemorrhagic neurological disorders, and intracranial hemorrhage which may be fatal. In addition, patients with dAVF often have cognitive impairments. This study assessed whether endovascular embolization improves cognitive performance in patients with dAVF. Methods: NAIF was a prospective study including all the patients with a clinical diagnosis of dAVF (excluding those with acute intracranial hemorrhage secondary to venous hypertension) who underwent successful embolization at 5 hospitals in Spain between January 4, 2018 and January 7, 2020. Patients were categorized by risk of hemorrhage (Cognard classification 1-2A and 2B-4) via angiography. A neuropsychological evaluation covering 5 domains of cognitive function (memory, attention and executive functions, language, praxis, gnosis) was completed at baseline and a 3-month follow-up. Paired sample t-tests were used to compare mean Z-scores for cognitive tests pre- and post-treatment, where higher Z-scores signify better cognitive status. Results: A preliminary group of 15 patients (mean age 60, [range 23-83 years], 4 [26.7%] female) were included. Six patients presented with low hemorrhagic risk (Cognard1-2A) and 9 with high hemorrhagic risk (Cognard 2B-4). In the post-treatment neuropsychological evaluation, patients exhibited improved performance in executive function in the Semantic and Phonetic Fluency test (-0.57 vs. 0.21; p=0.01) and increased performance in Verbal Memory Learning (-1.45 vs. -0.82; p=0.014) relative to baseline. The remaining cognitive evaluations did not show significant differences, although there was a trend of language improvement in the Boston naming test (0.95 vs. 1.12; p=0.093). Improvements were observed in both high- and low-risk patients, and no patients experienced cognitive worsening after the intervention. Conclusion: This study suggests that endovascular embolization imparts cognitive benefits for dAVF patients undergoing endovascular embolization, and may be beneficial even for patients with a low risk of hemorrhage.
Published: 2022

31. Aplicacions especials dels materials compostos amb fibres vegetals

Author: Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Claramunt Blanes, Josep, Ventura Casellas, Heura, Cruz Ortega, Gemma, Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia, Claramunt Blanes, Josep, Ventura Casellas, Heura, and Cruz Ortega, Gemma
Abstract: Actualmente, el impacto de la industria de la construcción está siendo una de las causas originarias del agotamiento de recursos no renovables además de la generación de grandes cantidades de residuos y de las emisiones de dióxido de carbono en la atmósfera. En interés de una estrategia de construcción más sostenible, en los últimos años se ha investigado exhaustivamente el uso de fibras vegetales, residuos y materiales reciclados. Como una buena opción, las fibras de residuos textiles junto con fibras vegetales se pueden utilizar como refuerzo interno en materiales con una matriz de cemento con el fin de mejorar su ductilidad y resistencia a las fisuras. Sin embargo, todos los estudios llevados a cabo hasta ahora han sido para placas planas, así pues, también es necesario analizar cuáles son las características en piezas curvadas. El objetivo de este trabajo es definir las características mecánicas de piezas curvadas de cemento reforzadas con no tejidos de residuo textil y fibras vegetales. Además de determinar la influencia del número de capas de no tejido y el grado de curvatura en sus propiedades. También se ha analizado el comportamiento del material en simulaciones numéricas. Para lograr el objetivo se elaboraron piezas con cuatro diámetros diferentes: 9, 16, 20 y 32 cm; y un reforzamiento con cuatro o seis capas de no tejido. Posteriormente, se analizaron sus propiedades mecánicas con un ensayo de flexión. Por otra parte, se compararon las tensiones calculadas con las ecuaciones descritas para placas planas y los resultados obtenidos con simulaciones numéricas atendiendo a la geometría de las piezas. Los resultados indicaron que las piezas de cemento reforzadas con seis capas de no tejido presentan mejores propiedades mecánicas que las reforzadas con cuatro capas. Respecto al grado de curvatura, se han observado diferencias significativas; las piezas de diámetro de 20 cm con seis capas han dado las tensiones más altas de entre todo el conjunto. Por lo que res, Currently, the construction industry's impact is one of the causes of the exhaustion of non-renewable resources as well as the generation of large amounts of waste and carbon dioxide emissions into the atmosphere. For the sake of a more sustainable construction strategy, the usage of vegetal fibres, waste and recycled materials has been extensively researched in the recent years. As a good option, textile waste fibres along with vegetal fibres can be used as internal reinforcement in materials with a cementitious matrix to improve their ductility and crack resistance. However, all studies carried out so far have been for flat plates, so it is necessary to analyse the characteristics of curved pieces. The aim of this work is to define the mechanical characteristics of curved concrete pieces reinforced with textile waste nonwovens and vegetal fibres. Moreover, it also aims to determine the influence of the number of nonwoven layers as well as the degree of curvature on their properties. The behaviour of the material has also been analysed in numerical simulations. In order to reach the objective, there were prepared composites with four different diameters: 9, 16, 20 and 32 cm; and reinforced with four or six layers of non-woven. Subsequently, their mechanical properties were analysed with a bending test. On the other hand, stresses values were compared depending if they were calculated with the equations described for flat plates or with numerical simulations according to their geometry. The results indicated that concrete pieces reinforced with six nonwoven layers have better mechanical properties than those reinforced with four layers. Significant differences were observed in relation to the degree of curvature; the pieces with a diameter of 20 cm with six layers gave the highest stresses among all the pieces. Regarding the methodology of stress calculation, the results of the simulations were superior to those of the equation, Actualment, l’impacte de la indústria de la construcció està sent una de les causes originàries de l’esgotament de recursos no renovables a més de la generació de grans quantitats de residus i de les emissions de diòxid de carboni a l’atmosfera. En interès d’una estratègia de construcció més sostenible, als darrers anys s’ha investigat exhaustivament l’ús de fibres vegetals, residus i materials reciclats. Com a una bona opció, les fibres de residus tèxtils juntament amb fibres vegetals es poden utilitzar com a reforç intern en materials amb una matriu de ciment amb la finalitat de millorar la seva ductilitat i la resistència a les esquerdes. No obstant, tots els estudis duts a terme fins ara han estat per a plaques planes, així doncs, també cal analitzar quines són les característiques en peces corbades. L’objectiu d’aquest treball és definir les característiques mecàniques de peces corbades de ciment reforçades amb no teixits de residu tèxtil i fibres vegetals. A més de determinar la influència del nombre de capes de no teixit i el grau de curvatura en les seves propietats. També s’ha analitzat el comportament del material en simulacions numèriques. Per arribar a l’objectiu es van elaborar peces amb quatre diàmetres diferents: 9, 16, 20 i 32 cm; i un reforçament amb quatre o sis capes de no teixit. Posteriorment, es van analitzar les seves propietats mecàniques amb un assaig de flexió. D’altra banda, es van comparar les tensions calculades amb les equacions descrites per a plaques planes i els resultats obtinguts amb simulacions numèriques tenint en compte la geometria de les peces. Els resultats han indicat que les peces de ciment reforçades amb sis capes de no teixit presenten millors propietats mecàniques que les reforçades amb quatre capes. Respecte al grau de curvatura, s’han observat diferències significatives; les peces de diàmetre de 20 cm amb sis capes han donat les tensions més altes d’entre tot el conjunt. Pel que fa a la metodologia de càlcul de les ten, Objectius de Desenvolupament Sostenible::9 - Indústria, Innovació i Infraestructura, Objectius de Desenvolupament Sostenible::12 - Producció i Consum Responsables
Published: 2022

32. Fibrosis pulmonar familiar

Author: Mora Ortega, Gemma María
Published: 2012
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33. Aplicacions especials dels materials compostos amb fibres vegetals

Author: Cruz Ortega, Gemma, Claramunt Blanes, Josep, Ventura Casellas, Heura, and Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia
Subjects: Ciment, Nonwoven fabrics, Material compost, Residus tèxtils, Teles no teixides, Enginyeria agroalimentària [Àrees temàtiques de la UPC], Fibres vegetals
Abstract: Actualmente, el impacto de la industria de la construcción está siendo una de las causas originarias del agotamiento de recursos no renovables además de la generación de grandes cantidades de residuos y de las emisiones de dióxido de carbono en la atmósfera. En interés de una estrategia de construcción más sostenible, en los últimos años se ha investigado exhaustivamente el uso de fibras vegetales, residuos y materiales reciclados. Como una buena opción, las fibras de residuos textiles junto con fibras vegetales se pueden utilizar como refuerzo interno en materiales con una matriz de cemento con el fin de mejorar su ductilidad y resistencia a las fisuras. Sin embargo, todos los estudios llevados a cabo hasta ahora han sido para placas planas, así pues, también es necesario analizar cuáles son las características en piezas curvadas. El objetivo de este trabajo es definir las características mecánicas de piezas curvadas de cemento reforzadas con no tejidos de residuo textil y fibras vegetales. Además de determinar la influencia del número de capas de no tejido y el grado de curvatura en sus propiedades. También se ha analizado el comportamiento del material en simulaciones numéricas. Para lograr el objetivo se elaboraron piezas con cuatro diámetros diferentes: 9, 16, 20 y 32 cm; y un reforzamiento con cuatro o seis capas de no tejido. Posteriormente, se analizaron sus propiedades mecánicas con un ensayo de flexión. Por otra parte, se compararon las tensiones calculadas con las ecuaciones descritas para placas planas y los resultados obtenidos con simulaciones numéricas atendiendo a la geometría de las piezas. Los resultados indicaron que las piezas de cemento reforzadas con seis capas de no tejido presentan mejores propiedades mecánicas que las reforzadas con cuatro capas. Respecto al grado de curvatura, se han observado diferencias significativas; las piezas de diámetro de 20 cm con seis capas han dado las tensiones más altas de entre todo el conjunto. Por lo que respecta a la metodología de cálculo de las tensiones, los resultados en las simulaciones son superiores a los de las ecuaciones. Currently, the construction industry's impact is one of the causes of the exhaustion of non-renewable resources as well as the generation of large amounts of waste and carbon dioxide emissions into the atmosphere. For the sake of a more sustainable construction strategy, the usage of vegetal fibres, waste and recycled materials has been extensively researched in the recent years. As a good option, textile waste fibres along with vegetal fibres can be used as internal reinforcement in materials with a cementitious matrix to improve their ductility and crack resistance. However, all studies carried out so far have been for flat plates, so it is necessary to analyse the characteristics of curved pieces. The aim of this work is to define the mechanical characteristics of curved concrete pieces reinforced with textile waste nonwovens and vegetal fibres. Moreover, it also aims to determine the influence of the number of nonwoven layers as well as the degree of curvature on their properties. The behaviour of the material has also been analysed in numerical simulations. In order to reach the objective, there were prepared composites with four different diameters: 9, 16, 20 and 32 cm; and reinforced with four or six layers of non-woven. Subsequently, their mechanical properties were analysed with a bending test. On the other hand, stresses values were compared depending if they were calculated with the equations described for flat plates or with numerical simulations according to their geometry. The results indicated that concrete pieces reinforced with six nonwoven layers have better mechanical properties than those reinforced with four layers. Significant differences were observed in relation to the degree of curvature; the pieces with a diameter of 20 cm with six layers gave the highest stresses among all the pieces. Regarding the methodology of stress calculation, the results of the simulations were superior to those of the equation Actualment, l’impacte de la indústria de la construcció està sent una de les causes originàries de l’esgotament de recursos no renovables a més de la generació de grans quantitats de residus i de les emissions de diòxid de carboni a l’atmosfera. En interès d’una estratègia de construcció més sostenible, als darrers anys s’ha investigat exhaustivament l’ús de fibres vegetals, residus i materials reciclats. Com a una bona opció, les fibres de residus tèxtils juntament amb fibres vegetals es poden utilitzar com a reforç intern en materials amb una matriu de ciment amb la finalitat de millorar la seva ductilitat i la resistència a les esquerdes. No obstant, tots els estudis duts a terme fins ara han estat per a plaques planes, així doncs, també cal analitzar quines són les característiques en peces corbades. L’objectiu d’aquest treball és definir les característiques mecàniques de peces corbades de ciment reforçades amb no teixits de residu tèxtil i fibres vegetals. A més de determinar la influència del nombre de capes de no teixit i el grau de curvatura en les seves propietats. També s’ha analitzat el comportament del material en simulacions numèriques. Per arribar a l’objectiu es van elaborar peces amb quatre diàmetres diferents: 9, 16, 20 i 32 cm; i un reforçament amb quatre o sis capes de no teixit. Posteriorment, es van analitzar les seves propietats mecàniques amb un assaig de flexió. D’altra banda, es van comparar les tensions calculades amb les equacions descrites per a plaques planes i els resultats obtinguts amb simulacions numèriques tenint en compte la geometria de les peces. Els resultats han indicat que les peces de ciment reforçades amb sis capes de no teixit presenten millors propietats mecàniques que les reforçades amb quatre capes. Respecte al grau de curvatura, s’han observat diferències significatives; les peces de diàmetre de 20 cm amb sis capes han donat les tensions més altes d’entre tot el conjunt. Pel que fa a la metodologia de càlcul de les tensions, els resultats en les simulacions són superiors als de les equacions. Objectius de Desenvolupament Sostenible::9 - Indústria, Innovació i Infraestructura Objectius de Desenvolupament Sostenible::12 - Producció i Consum Responsables
Published: 2022

34. Neuropsychiatric Profile as a Predictor of Cognitive Decline in Mild Cognitive Impairment

Author: Roberto, Natalia, primary, Portella, Maria J., additional, Marquié, Marta, additional, Alegret, Montserrat, additional, Hernández, Isabel, additional, Mauleón, Ana, additional, Rosende-Roca, Maitee, additional, Abdelnour, Carla, additional, Esteban de Antonio, Ester, additional, Tartari, Juan P., additional, Vargas, Liliana, additional, López-Cuevas, Rogelio, additional, Bojaryn, Urszula, additional, Espinosa, Ana, additional, Ortega, Gemma, additional, Pérez-Cordón, Alba, additional, Sanabria, Ángela, additional, Orellana, Adelina, additional, de Rojas, Itziar, additional, Moreno-Grau, Sonia, additional, Montrreal, Laura, additional, Alarcón-Martín, Emilio, additional, Ruíz, Agustín, additional, Tárraga, Lluís, additional, Boada, Mercè, additional, and Valero, Sergi, additional
Published: 2021
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35. Metabolic syndrome impact on cognitive composites domain scores and on white matter hyperintensities in subjective cognitive decline: The FACEHBI Cohort

Author: Ortega, Gemma, primary, Espinosa, Ana, additional, Alegret, Montserrat, additional, Monté‐Rubio, Gemma, additional, Sotolongo‐Grau, Oscar, additional, Sanabria, Angela, additional, Tartari, Juan Pablo, additional, Rodriguez‐Gomez, Octavio, additional, Marquié, Marta, additional, Vivas, Assumpta, additional, Gómez‐Chiari, M, additional, Alarcón‐Martín, Emilio, additional, Pérez‐Cordón, Alba, additional, Roberto, Natalia, additional, Hernandez, Isabel, additional, Rosende‐Roca, Maitee, additional, Vargas, Liliana, additional, Mauleon, Ana, additional, Abdelnour, Carla, additional, Antonio, Ester Esteban‐De, additional, López‐Cuevas, Rogelio, additional, Alonso‐Lana, S, additional, Moreno‐Grau, Sonia, additional, de Rojas, Itziar, additional, Orellana, Adelina, additional, Montrreal, Laura, additional, Tarraga, Lluis, additional, Ruiz, Agustin, additional, Boada, Mercè, additional, and Valero, Sergi, additional
Published: 2021
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36. Functional respiratory impairment and related factors in patients with interstitial pneumonia with autoimmune features (IPAF): Multicenter study from NEREA registry.

Author: Nieto, Maria Asuncion, Sanchez-Pernaute, Olga, Vadillo, Cristina, Rodriguez-Nieto, Maria Jesus, Romero-Bueno, Fredeswinda, López-Muñiz, Belen, Cebrian, Laura, Rio-Ramirez, Maria Teresa, Laporta, Rosalia, Bonilla, Gema, Cobo, Tatiana, Leon, Leticia, Abasolo, Lydia, NEREA Group, Lores, Irene Martín, de Castro, Ana Bustos Garcia, Pernaute, Olga Sanchez, Palacios, Carmelo, Carrera, Luis Gomez, and Ortega, Gemma Mora
Subjects: PULMONARY fibrosis, IDIOPATHIC pulmonary fibrosis, MULTIVARIATE analysis
Abstract: Background: The objective of the present study is to describe the characteristics of interstitial pneumonia with autoimmune features (IPAF) patients, to assess the incidence rate of functional respiratory impairment over time and to evaluate the influence of therapeutic alternatives on the prognosis of these patients. Methods: A longitudinal observational multicenter study was performed (NEREA registry). It was carried out by a multidisciplinary team in seven Hospitals of Madrid. Patients were included from IPAF diagnosis. Main outcome: poor prognosis as functional respiratory impairment (relative decline in FVC % defined as ≥ 5% every 6 months). Covariates: therapy, sociodemographic, clinical, radiological patterns, laboratory and functional tests. Statistics: Survival techniques were used to estimate IR per 100 patients-semester with their 95% confidence interval [CI]. The influence of covariates in prognosis were analyzed through cox multivariate regression models (hazard ratio (HR) and [CI]). Results: 79 IPAF were included, with a mean and a maximum follow-up of 3.17 and 12 years respectively. Along the study, 77.2% received treatment (52 glucocorticoids, 25 mycophenolate, 21 azathioprine, 15 rituximab and 11 antifibrotics). IR was 23.9 [19.9–28.8], and 50% of IPAF developed functional respiratory impairment after 16 months from its diagnosis. Multivariate analysis: usual interstitial pneumonia (UIP) had poorer prognosis compared to non-specific interstitial pneumonia (NSIP) (p = 0.001). In NSIP, positive ANA, increased the risk of poor prognosis. In UIP, glucocorticoids (HR: 0.53 [0.34–0.83]), age (HR: 1.04 [1.01–1.07]), and Ro-antibodies (HR: 0.36 [0.19–0.65]) influenced the prognosis. Conclusions: IPAF have functional impairment during the first years of disease. Factors predicting deterioration differ between radiographic patterns. Our real-life study suggests the potential benefit of particular therapies in IPAF. [ABSTRACT FROM AUTHOR]
Published: 2023
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37. Validation of the Spanish Version of the Face Name Associative Memory Exam (S-FNAME) in Cognitively Normal Older Individuals

Author: Alegret, Montserrat, Valero, Sergi, Ortega, Gemma, Espinosa, Ana, Sanabria, Angela, Hernández, Isabel, Rodríguez, Octavio, Rosende-Roca, Maitee, Mauleón, Ana, Vargas, Liliana, Martín, Elvira, Ruíz, Agustín, Tárraga, Lluís, Amariglio, Rebecca E., Rentz, Dorene M., and Boada, Mercè
Published: 2015
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38. Cux1 and Cux2 selectively target basal and apical dendritic compartments of layer II-III cortical neurons

Author: Cubelos, Beatriz, Briz, Carlos G., María Esteban-Ortega, Gemma, and Nieto, Marta
Published: 2015
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39. From Face-to-Face to Home-to-Home: Validity of a Teleneuropsychological Battery

Author: Alegret, Montserrat, primary, Espinosa, Ana, additional, Ortega, Gemma, additional, Pérez-Cordón, Alba, additional, Sanabria, Ángela, additional, Hernández, Isabel, additional, Marquié, Marta, additional, Rosende-Roca, Maitée, additional, Mauleón, Ana, additional, Abdelnour, Carla, additional, Vargas, Liliana, additional, de Antonio, Ester Esteban, additional, López-Cuevas, Rogelio, additional, Tartari, Juan Pablo, additional, Alarcón-Martín, Emilio, additional, Tárraga, Lluís, additional, Ruiz, Agustín, additional, Boada, Mercè, additional, and Valero, Sergi, additional
Published: 2021
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40. Biomarker-Based Risk Prediction of Alzheimer's Disease Dementia in Mild Cognitive Impairment: Psychosocial, Ethical, and Legal Aspects Study Protocol of the PreDADQoL Project

Author: Rostamzadeh, Ayda, Schwegler, Carolin, Gil-Navarro, Silvia, Rosende-Roca, Maitee, Romotzky, Vanessa, Ortega, Gemma, Canabate, Pilar, Moreno, Mariola, Schmitz-Luhn, Bjoern, Boada, Merce, Jessen, Frank, Woopen, Christiane, Rostamzadeh, Ayda, Schwegler, Carolin, Gil-Navarro, Silvia, Rosende-Roca, Maitee, Romotzky, Vanessa, Ortega, Gemma, Canabate, Pilar, Moreno, Mariola, Schmitz-Luhn, Bjoern, Boada, Merce, Jessen, Frank, and Woopen, Christiane
Abstract: Background: Today, a growing number of individuals with mild cognitive impairment (MCI) wish to assess their risk of developing Alzheimer's disease (AD) dementia. The expectations as well as the effects on quality of life (QoL) in MCI patients and their close others through biomarker-based dementia risk estimation are not well studied. Objective: The PreDADQoL project aims at providing empirical data on effects of such prediction on QoL and at developing an ethical and legal framework of biomarker-based dementia risk estimation in MCI. Methods: In the empirical study, 100 MCI-patients and their close others will be recruited from two sites (Germany and Spain). They receive standardized counselling on cerebrospinal fluid (CSF) biomarker-based prediction of AD dementia and a risk disclosure based on their AD biomarker status. A mixed methods approach will be applied to assess outcomes. Results: The pilot-study yielded a specification of the research topics and newly developed questionnaires for the main assessment. Within this binational quantitative and qualitative study, data on attitudes and expectations toward AD risk prediction, QoL, risk communication, coping strategies, mental health, lifestyle changes, and healthcare resource utilization will be obtained. Together with the normative part of the project, an empirically informed ethical and legal framework for biomarker-based dementia risk estimation will be developed. Conclusion: The empirical research of the PreDADQoL study together with the ethical and legal considerations and implications will help to improve the process of counselling and risk disclosure and thereby positively affect QoL and health of MCI-patients and their close others in the context of biomarker-based dementia risk estimation.
Published: 2021

41. Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

Author: de Rojas, I, Moreno-Grau, S, Tesi, N, Grenier-Boley, B, Andrade, V, Jansen, I, Pedersen, N, Stringa, N, Zettergren, A, Hernández, I, Montrreal, L, Antúnez, C, Antonell, A, Tankard, R, Bis, J, Sims, R, Bellenguez, C, Quintela, I, González-Perez, A, Calero, M, Franco-Macías, E, Macías, J, Blesa, R, Cervera-Carles, L, Menéndez-González, M, Frank-García, A, Royo, J, Moreno, F, Huerto Vilas, R, Baquero, M, Diez-Fairen, M, Lage, C, García-Madrona, S, García-González, P, Alarcón-Martín, E, Valero, S, Sotolongo-Grau, O, Ullgren, A, Naj, A, Lemstra, A, Benaque, A, Pérez-Cordón, A, Benussi, A, Rábano, A, Padovani, A, Squassina, A, de Mendonça, A, Arias Pastor, A, Kok, A, Meggy, A, Pastor, A, Espinosa, A, Corma-Gómez, A, Martín Montes, A, Sanabria, Á, Destefano, A, Schneider, A, Haapasalo, A, Kinhult Ståhlbom, A, Tybjærg-Hansen, A, Hartmann, A, Spottke, A, Corbatón-Anchuelo, A, Rongve, A, Borroni, B, Arosio, B, Nacmias, B, Nordestgaard, B, Kunkle, B, Charbonnier, C, Abdelnour, C, Masullo, C, Martínez Rodríguez, C, Muñoz-Fernandez, C, Dufouil, C, Graff, C, Ferreira, C, Chillotti, C, Reynolds, C, Fenoglio, C, Van Broeckhoven, C, Clark, C, Pisanu, C, Satizabal, C, Holmes, C, Buiza-Rueda, D, Aarsland, D, Rujescu, D, Alcolea, D, Galimberti, D, Wallon, D, Seripa, D, Grünblatt, E, Dardiotis, E, Düzel, E, Scarpini, E, Conti, E, Rubino, E, Gelpi, E, Rodriguez-Rodriguez, E, Duron, E, Boerwinkle, E, Ferri, E, Tagliavini, F, Küçükali, F, Pasquier, F, Sanchez-Garcia, F, Mangialasche, F, Jessen, F, Nicolas, G, Selbæk, G, Ortega, G, Chêne, G, Hadjigeorgiou, G, Rossi, G, Spalletta, G, Giaccone, G, Grande, G, Binetti, G, Papenberg, G, Hampel, H, Bailly, H, Zetterberg, H, Soininen, H, Karlsson, I, Alvarez, I, Appollonio, I, Giegling, I, Skoog, I, Saltvedt, I, Rainero, I, Rosas Allende, I, Hort, J, Diehl-Schmid, J, Van Dongen, J, Vidal, J, Lehtisalo, J, Wiltfang, J, Thomassen, J, Kornhuber, J, Haines, J, Vogelgsang, J, Pineda, J, Fortea, J, Popp, J, Deckert, J, Buerger, K, Morgan, K, Fließbach, K, Sleegers, K, Molina-Porcel, L, Kilander, L, Weinhold, L, Farrer, L, Wang, L, Kleineidam, L, Farotti, L, Parnetti, L, Tremolizzo, L, Hausner, L, Benussi, L, Froelich, L, Ikram, M, Deniz-Naranjo, M, Tsolaki, M, Rosende-Roca, M, Löwenmark, M, Hulsman, M, Spallazzi, M, Pericak-Vance, M, Esiri, M, Bernal Sánchez-Arjona, M, Dalmasso, M, Martínez-Larrad, M, Arcaro, M, Nöthen, M, Fernández-Fuertes, M, Dichgans, M, Ingelsson, M, Herrmann, M, Scherer, M, Vyhnalek, M, Kosmidis, M, Yannakoulia, M, Schmid, M, Ewers, M, Heneka, M, Wagner, M, Scamosci, M, Kivipelto, M, Hiltunen, M, Zulaica, M, Alegret, M, Fornage, M, Roberto, N, van Schoor, N, Seidu, N, Banaj, N, Armstrong, N, Scarmeas, N, Scherbaum, N, Goldhardt, O, Hanon, O, Peters, O, Skrobot, O, Quenez, O, Lerch, O, Bossù, P, Caffarra, P, Dionigi Rossi, P, Sakka, P, Hoffmann, P, Holmans, P, Fischer, P, Riederer, P, Yang, Q, Marshall, R, Kalaria, R, Mayeux, R, Vandenberghe, R, Cecchetti, R, Ghidoni, R, Frikke-Schmidt, R, Sorbi, S, Hägg, S, Engelborghs, S, Helisalmi, S, Botne Sando, S, Kern, S, Archetti, S, Boschi, S, Fostinelli, S, Gil, S, Mendoza, S, Mead, S, Ciccone, S, Djurovic, S, Heilmann-Heimbach, S, Riedel-Heller, S, Kuulasmaa, T, Del Ser, T, Lebouvier, T, Polak, T, Ngandu, T, Grimmer, T, Bessi, V, Escott-Price, V, Giedraitis, V, Deramecourt, V, Maier, W, Jian, X, Pijnenburg, Y, Andreoni, S, Ferrarese, C, Sala, G, Zoia, C, Kehoe, P, Garcia-Ribas, G, Sánchez-Juan, P, Pastor, P, Pérez-Tur, J, Piñol-Ripoll, G, Lopez de Munain, A, García-Alberca, J, Bullido, M, Álvarez, V, Lleó, A, Real, L, Mir, P, Medina, M, Scheltens, P, Holstege, H, Marquié, M, Sáez, M, Carracedo, Á, Amouyel, P, Schellenberg, G, Williams, J, Seshadri, S, van Duijn, C, Mather, K, Sánchez-Valle, R, Serrano-Ríos, M, Orellana, A, Tárraga, L, Blennow, K, Huisman, M, Andreassen, O, Posthuma, D, Clarimón, J, Boada, M, van der Flier, W, Ramirez, A, Lambert, J, van der Lee, S, Ruiz, A, de Rojas, Itziar, Moreno-Grau, Sonia, Tesi, Niccolo, Grenier-Boley, Benjamin, Andrade, Victor, Jansen, Iris E, Pedersen, Nancy L, Stringa, Najada, Zettergren, Anna, Hernández, Isabel, Montrreal, Laura, Antúnez, Carmen, Antonell, Anna, Tankard, Rick M, Bis, Joshua C, Sims, Rebecca, Bellenguez, Céline, Quintela, Inés, González-Perez, Antonio, Calero, Miguel, Franco-Macías, Emilio, Macías, Juan, Blesa, Rafael, Cervera-Carles, Laura, Menéndez-González, Manuel, Frank-García, Ana, Royo, Jose Luís, Moreno, Fermin, Huerto Vilas, Raquel, Baquero, Miquel, Diez-Fairen, Mónica, Lage, Carmen, García-Madrona, Sebastián, García-González, Pablo, Alarcón-Martín, Emilio, Valero, Sergi, Sotolongo-Grau, Oscar, Ullgren, Abbe, Naj, Adam C, Lemstra, Afina W, Benaque, Alba, Pérez-Cordón, Alba, Benussi, Alberto, Rábano, Alberto, Padovani, Alessandro, Squassina, Alessio, de Mendonça, Alexandre, Arias Pastor, Alfonso, Kok, Almar A L, Meggy, Alun, Pastor, Ana Belén, Espinosa, Ana, Corma-Gómez, Anas, Martín Montes, Angel, Sanabria, Ángela, DeStefano, Anita L, Schneider, Anja, Haapasalo, Annakaisa, Kinhult Ståhlbom, Anne, Tybjærg-Hansen, Anne, Hartmann, Annette M, Spottke, Annika, Corbatón-Anchuelo, Arturo, Rongve, Arvid, Borroni, Barbara, Arosio, Beatrice, Nacmias, Benedetta, Nordestgaard, Børge G, Kunkle, Brian W, Charbonnier, Camille, Abdelnour, Carla, Masullo, Carlo, Martínez Rodríguez, Carmen, Muñoz-Fernandez, Carmen, Dufouil, Carole, Graff, Caroline, Ferreira, Catarina B, Chillotti, Caterina, Reynolds, Chandra A, Fenoglio, Chiara, Van Broeckhoven, Christine, Clark, Christopher, Pisanu, Claudia, Satizabal, Claudia L, Holmes, Clive, Buiza-Rueda, Dolores, Aarsland, Dag, Rujescu, Dan, Alcolea, Daniel, Galimberti, Daniela, Wallon, David, Seripa, Davide, Grünblatt, Edna, Dardiotis, Efthimios, Düzel, Emrah, Scarpini, Elio, Conti, Elisa, Rubino, Elisa, Gelpi, Ellen, Rodriguez-Rodriguez, Eloy, Duron, Emmanuelle, Boerwinkle, Eric, Ferri, Evelyn, Tagliavini, Fabrizio, Küçükali, Fahri, Pasquier, Florence, Sanchez-Garcia, Florentino, Mangialasche, Francesca, Jessen, Frank, Nicolas, Gaël, Selbæk, Geir, Ortega, Gemma, Chêne, Geneviève, Hadjigeorgiou, Georgios, Rossi, Giacomina, Spalletta, Gianfranco, Giaccone, Giorgio, Grande, Giulia, Binetti, Giuliano, Papenberg, Goran, Hampel, Harald, Bailly, Henri, Zetterberg, Henrik, Soininen, Hilkka, Karlsson, Ida K, Alvarez, Ignacio, Appollonio, Ildebrando, Giegling, Ina, Skoog, Ingmar, Saltvedt, Ingvild, Rainero, Innocenzo, Rosas Allende, Irene, Hort, Jakub, Diehl-Schmid, Janine, Van Dongen, Jasper, Vidal, Jean-Sebastien, Lehtisalo, Jenni, Wiltfang, Jens, Thomassen, Jesper Qvist, Kornhuber, Johannes, Haines, Jonathan L, Vogelgsang, Jonathan, Pineda, Juan A, Fortea, Juan, Popp, Julius, Deckert, Jürgen, Buerger, Katharina, Morgan, Kevin, Fließbach, Klaus, Sleegers, Kristel, Molina-Porcel, Laura, Kilander, Lena, Weinhold, Leonie, Farrer, Lindsay A, Wang, Li-San, Kleineidam, Luca, Farotti, Lucia, Parnetti, Lucilla, Tremolizzo, Lucio, Hausner, Lucrezia, Benussi, Luisa, Froelich, Lutz, Ikram, M Arfan, Deniz-Naranjo, M Candida, Tsolaki, Magda, Rosende-Roca, Maitée, Löwenmark, Malin, Hulsman, Marc, Spallazzi, Marco, Pericak-Vance, Margaret A, Esiri, Margaret, Bernal Sánchez-Arjona, María, Dalmasso, Maria Carolina, Martínez-Larrad, María Teresa, Arcaro, Marina, Nöthen, Markus M, Fernández-Fuertes, Marta, Dichgans, Martin, Ingelsson, Martin, Herrmann, Martin J, Scherer, Martin, Vyhnalek, Martin, Kosmidis, Mary H, Yannakoulia, Mary, Schmid, Matthias, Ewers, Michael, Heneka, Michael T, Wagner, Michael, Scamosci, Michela, Kivipelto, Miia, Hiltunen, Mikko, Zulaica, Miren, Alegret, Montserrat, Fornage, Myriam, Roberto, Natalia, van Schoor, Natasja M, Seidu, Nazib M, Banaj, Nerisa, Armstrong, Nicola J, Scarmeas, Nikolaos, Scherbaum, Norbert, Goldhardt, Oliver, Hanon, Oliver, Peters, Oliver, Skrobot, Olivia Anna, Quenez, Olivier, Lerch, Ondrej, Bossù, Paola, Caffarra, Paolo, Dionigi Rossi, Paolo, Sakka, Paraskevi, Hoffmann, Per, Holmans, Peter A, Fischer, Peter, Riederer, Peter, Yang, Qiong, Marshall, Rachel, Kalaria, Rajesh N, Mayeux, Richard, Vandenberghe, Rik, Cecchetti, Roberta, Ghidoni, Roberta, Frikke-Schmidt, Ruth, Sorbi, Sandro, Hägg, Sara, Engelborghs, Sebastiaan, Helisalmi, Seppo, Botne Sando, Sigrid, Kern, Silke, Archetti, Silvana, Boschi, Silvia, Fostinelli, Silvia, Gil, Silvia, Mendoza, Silvia, Mead, Simon, Ciccone, Simona, Djurovic, Srdjan, Heilmann-Heimbach, Stefanie, Riedel-Heller, Steffi, Kuulasmaa, Teemu, Del Ser, Teodoro, Lebouvier, Thibaud, Polak, Thomas, Ngandu, Tiia, Grimmer, Timo, Bessi, Valentina, Escott-Price, Valentina, Giedraitis, Vilmantas, Deramecourt, Vincent, Maier, Wolfgang, Jian, Xueqiu, Pijnenburg, Yolande A L, Andreoni, Simona, Ferrarese, Carlo, Sala Gessica, Zoia, Chiara Paola, Kehoe, Patrick Gavin, Garcia-Ribas, Guillermo, Sánchez-Juan, Pascual, Pastor, Pau, Pérez-Tur, Jordi, Piñol-Ripoll, Gerard, Lopez de Munain, Adolfo, García-Alberca, Jose María, Bullido, María J, Álvarez, Victoria, Lleó, Alberto, Real, Luis M, Mir, Pablo, Medina, Miguel, Scheltens, Philip, Holstege, Henne, Marquié, Marta, Sáez, María Eugenia, Carracedo, Ángel, Amouyel, Philippe, Schellenberg, Gerard D, Williams, Julie, Seshadri, Sudha, van Duijn, Cornelia M, Mather, Karen A, Sánchez-Valle, Raquel, Serrano-Ríos, Manuel, Orellana, Adelina, Tárraga, Lluís, Blennow, Kaj, Huisman, Martijn, Andreassen, Ole A, Posthuma, Danielle, Clarimón, Jordi, Boada, Mercè, van der Flier, Wiesje M, Ramirez, Alfredo, Lambert, Jean-Charles, van der Lee, Sven J, Ruiz, Agustín, de Rojas, I, Moreno-Grau, S, Tesi, N, Grenier-Boley, B, Andrade, V, Jansen, I, Pedersen, N, Stringa, N, Zettergren, A, Hernández, I, Montrreal, L, Antúnez, C, Antonell, A, Tankard, R, Bis, J, Sims, R, Bellenguez, C, Quintela, I, González-Perez, A, Calero, M, Franco-Macías, E, Macías, J, Blesa, R, Cervera-Carles, L, Menéndez-González, M, Frank-García, A, Royo, J, Moreno, F, Huerto Vilas, R, Baquero, M, Diez-Fairen, M, Lage, C, García-Madrona, S, García-González, P, Alarcón-Martín, E, Valero, S, Sotolongo-Grau, O, Ullgren, A, Naj, A, Lemstra, A, Benaque, A, Pérez-Cordón, A, Benussi, A, Rábano, A, Padovani, A, Squassina, A, de Mendonça, A, Arias Pastor, A, Kok, A, Meggy, A, Pastor, A, Espinosa, A, Corma-Gómez, A, Martín Montes, A, Sanabria, Á, Destefano, A, Schneider, A, Haapasalo, A, Kinhult Ståhlbom, A, Tybjærg-Hansen, A, Hartmann, A, Spottke, A, Corbatón-Anchuelo, A, Rongve, A, Borroni, B, Arosio, B, Nacmias, B, Nordestgaard, B, Kunkle, B, Charbonnier, C, Abdelnour, C, Masullo, C, Martínez Rodríguez, C, Muñoz-Fernandez, C, Dufouil, C, Graff, C, Ferreira, C, Chillotti, C, Reynolds, C, Fenoglio, C, Van Broeckhoven, C, Clark, C, Pisanu, C, Satizabal, C, Holmes, C, Buiza-Rueda, D, Aarsland, D, Rujescu, D, Alcolea, D, Galimberti, D, Wallon, D, Seripa, D, Grünblatt, E, Dardiotis, E, Düzel, E, Scarpini, E, Conti, E, Rubino, E, Gelpi, E, Rodriguez-Rodriguez, E, Duron, E, Boerwinkle, E, Ferri, E, Tagliavini, F, Küçükali, F, Pasquier, F, Sanchez-Garcia, F, Mangialasche, F, Jessen, F, Nicolas, G, Selbæk, G, Ortega, G, Chêne, G, Hadjigeorgiou, G, Rossi, G, Spalletta, G, Giaccone, G, Grande, G, Binetti, G, Papenberg, G, Hampel, H, Bailly, H, Zetterberg, H, Soininen, H, Karlsson, I, Alvarez, I, Appollonio, I, Giegling, I, Skoog, I, Saltvedt, I, Rainero, I, Rosas Allende, I, Hort, J, Diehl-Schmid, J, Van Dongen, J, Vidal, J, Lehtisalo, J, Wiltfang, J, Thomassen, J, Kornhuber, J, Haines, J, Vogelgsang, J, Pineda, J, Fortea, J, Popp, J, Deckert, J, Buerger, K, Morgan, K, Fließbach, K, Sleegers, K, Molina-Porcel, L, Kilander, L, Weinhold, L, Farrer, L, Wang, L, Kleineidam, L, Farotti, L, Parnetti, L, Tremolizzo, L, Hausner, L, Benussi, L, Froelich, L, Ikram, M, Deniz-Naranjo, M, Tsolaki, M, Rosende-Roca, M, Löwenmark, M, Hulsman, M, Spallazzi, M, Pericak-Vance, M, Esiri, M, Bernal Sánchez-Arjona, M, Dalmasso, M, Martínez-Larrad, M, Arcaro, M, Nöthen, M, Fernández-Fuertes, M, Dichgans, M, Ingelsson, M, Herrmann, M, Scherer, M, Vyhnalek, M, Kosmidis, M, Yannakoulia, M, Schmid, M, Ewers, M, Heneka, M, Wagner, M, Scamosci, M, Kivipelto, M, Hiltunen, M, Zulaica, M, Alegret, M, Fornage, M, Roberto, N, van Schoor, N, Seidu, N, Banaj, N, Armstrong, N, Scarmeas, N, Scherbaum, N, Goldhardt, O, Hanon, O, Peters, O, Skrobot, O, Quenez, O, Lerch, O, Bossù, P, Caffarra, P, Dionigi Rossi, P, Sakka, P, Hoffmann, P, Holmans, P, Fischer, P, Riederer, P, Yang, Q, Marshall, R, Kalaria, R, Mayeux, R, Vandenberghe, R, Cecchetti, R, Ghidoni, R, Frikke-Schmidt, R, Sorbi, S, Hägg, S, Engelborghs, S, Helisalmi, S, Botne Sando, S, Kern, S, Archetti, S, Boschi, S, Fostinelli, S, Gil, S, Mendoza, S, Mead, S, Ciccone, S, Djurovic, S, Heilmann-Heimbach, S, Riedel-Heller, S, Kuulasmaa, T, Del Ser, T, Lebouvier, T, Polak, T, Ngandu, T, Grimmer, T, Bessi, V, Escott-Price, V, Giedraitis, V, Deramecourt, V, Maier, W, Jian, X, Pijnenburg, Y, Andreoni, S, Ferrarese, C, Sala, G, Zoia, C, Kehoe, P, Garcia-Ribas, G, Sánchez-Juan, P, Pastor, P, Pérez-Tur, J, Piñol-Ripoll, G, Lopez de Munain, A, García-Alberca, J, Bullido, M, Álvarez, V, Lleó, A, Real, L, Mir, P, Medina, M, Scheltens, P, Holstege, H, Marquié, M, Sáez, M, Carracedo, Á, Amouyel, P, Schellenberg, G, Williams, J, Seshadri, S, van Duijn, C, Mather, K, Sánchez-Valle, R, Serrano-Ríos, M, Orellana, A, Tárraga, L, Blennow, K, Huisman, M, Andreassen, O, Posthuma, D, Clarimón, J, Boada, M, van der Flier, W, Ramirez, A, Lambert, J, van der Lee, S, Ruiz, A, de Rojas, Itziar, Moreno-Grau, Sonia, Tesi, Niccolo, Grenier-Boley, Benjamin, Andrade, Victor, Jansen, Iris E, Pedersen, Nancy L, Stringa, Najada, Zettergren, Anna, Hernández, Isabel, Montrreal, Laura, Antúnez, Carmen, Antonell, Anna, Tankard, Rick M, Bis, Joshua C, Sims, Rebecca, Bellenguez, Céline, Quintela, Inés, González-Perez, Antonio, Calero, Miguel, Franco-Macías, Emilio, Macías, Juan, Blesa, Rafael, Cervera-Carles, Laura, Menéndez-González, Manuel, Frank-García, Ana, Royo, Jose Luís, Moreno, Fermin, Huerto Vilas, Raquel, Baquero, Miquel, Diez-Fairen, Mónica, Lage, Carmen, García-Madrona, Sebastián, García-González, Pablo, Alarcón-Martín, Emilio, Valero, Sergi, Sotolongo-Grau, Oscar, Ullgren, Abbe, Naj, Adam C, Lemstra, Afina W, Benaque, Alba, Pérez-Cordón, Alba, Benussi, Alberto, Rábano, Alberto, Padovani, Alessandro, Squassina, Alessio, de Mendonça, Alexandre, Arias Pastor, Alfonso, Kok, Almar A L, Meggy, Alun, Pastor, Ana Belén, Espinosa, Ana, Corma-Gómez, Anas, Martín Montes, Angel, Sanabria, Ángela, DeStefano, Anita L, Schneider, Anja, Haapasalo, Annakaisa, Kinhult Ståhlbom, Anne, Tybjærg-Hansen, Anne, Hartmann, Annette M, Spottke, Annika, Corbatón-Anchuelo, Arturo, Rongve, Arvid, Borroni, Barbara, Arosio, Beatrice, Nacmias, Benedetta, Nordestgaard, Børge G, Kunkle, Brian W, Charbonnier, Camille, Abdelnour, Carla, Masullo, Carlo, Martínez Rodríguez, Carmen, Muñoz-Fernandez, Carmen, Dufouil, Carole, Graff, Caroline, Ferreira, Catarina B, Chillotti, Caterina, Reynolds, Chandra A, Fenoglio, Chiara, Van Broeckhoven, Christine, Clark, Christopher, Pisanu, Claudia, Satizabal, Claudia L, Holmes, Clive, Buiza-Rueda, Dolores, Aarsland, Dag, Rujescu, Dan, Alcolea, Daniel, Galimberti, Daniela, Wallon, David, Seripa, Davide, Grünblatt, Edna, Dardiotis, Efthimios, Düzel, Emrah, Scarpini, Elio, Conti, Elisa, Rubino, Elisa, Gelpi, Ellen, Rodriguez-Rodriguez, Eloy, Duron, Emmanuelle, Boerwinkle, Eric, Ferri, Evelyn, Tagliavini, Fabrizio, Küçükali, Fahri, Pasquier, Florence, Sanchez-Garcia, Florentino, Mangialasche, Francesca, Jessen, Frank, Nicolas, Gaël, Selbæk, Geir, Ortega, Gemma, Chêne, Geneviève, Hadjigeorgiou, Georgios, Rossi, Giacomina, Spalletta, Gianfranco, Giaccone, Giorgio, Grande, Giulia, Binetti, Giuliano, Papenberg, Goran, Hampel, Harald, Bailly, Henri, Zetterberg, Henrik, Soininen, Hilkka, Karlsson, Ida K, Alvarez, Ignacio, Appollonio, Ildebrando, Giegling, Ina, Skoog, Ingmar, Saltvedt, Ingvild, Rainero, Innocenzo, Rosas Allende, Irene, Hort, Jakub, Diehl-Schmid, Janine, Van Dongen, Jasper, Vidal, Jean-Sebastien, Lehtisalo, Jenni, Wiltfang, Jens, Thomassen, Jesper Qvist, Kornhuber, Johannes, Haines, Jonathan L, Vogelgsang, Jonathan, Pineda, Juan A, Fortea, Juan, Popp, Julius, Deckert, Jürgen, Buerger, Katharina, Morgan, Kevin, Fließbach, Klaus, Sleegers, Kristel, Molina-Porcel, Laura, Kilander, Lena, Weinhold, Leonie, Farrer, Lindsay A, Wang, Li-San, Kleineidam, Luca, Farotti, Lucia, Parnetti, Lucilla, Tremolizzo, Lucio, Hausner, Lucrezia, Benussi, Luisa, Froelich, Lutz, Ikram, M Arfan, Deniz-Naranjo, M Candida, Tsolaki, Magda, Rosende-Roca, Maitée, Löwenmark, Malin, Hulsman, Marc, Spallazzi, Marco, Pericak-Vance, Margaret A, Esiri, Margaret, Bernal Sánchez-Arjona, María, Dalmasso, Maria Carolina, Martínez-Larrad, María Teresa, Arcaro, Marina, Nöthen, Markus M, Fernández-Fuertes, Marta, Dichgans, Martin, Ingelsson, Martin, Herrmann, Martin J, Scherer, Martin, Vyhnalek, Martin, Kosmidis, Mary H, Yannakoulia, Mary, Schmid, Matthias, Ewers, Michael, Heneka, Michael T, Wagner, Michael, Scamosci, Michela, Kivipelto, Miia, Hiltunen, Mikko, Zulaica, Miren, Alegret, Montserrat, Fornage, Myriam, Roberto, Natalia, van Schoor, Natasja M, Seidu, Nazib M, Banaj, Nerisa, Armstrong, Nicola J, Scarmeas, Nikolaos, Scherbaum, Norbert, Goldhardt, Oliver, Hanon, Oliver, Peters, Oliver, Skrobot, Olivia Anna, Quenez, Olivier, Lerch, Ondrej, Bossù, Paola, Caffarra, Paolo, Dionigi Rossi, Paolo, Sakka, Paraskevi, Hoffmann, Per, Holmans, Peter A, Fischer, Peter, Riederer, Peter, Yang, Qiong, Marshall, Rachel, Kalaria, Rajesh N, Mayeux, Richard, Vandenberghe, Rik, Cecchetti, Roberta, Ghidoni, Roberta, Frikke-Schmidt, Ruth, Sorbi, Sandro, Hägg, Sara, Engelborghs, Sebastiaan, Helisalmi, Seppo, Botne Sando, Sigrid, Kern, Silke, Archetti, Silvana, Boschi, Silvia, Fostinelli, Silvia, Gil, Silvia, Mendoza, Silvia, Mead, Simon, Ciccone, Simona, Djurovic, Srdjan, Heilmann-Heimbach, Stefanie, Riedel-Heller, Steffi, Kuulasmaa, Teemu, Del Ser, Teodoro, Lebouvier, Thibaud, Polak, Thomas, Ngandu, Tiia, Grimmer, Timo, Bessi, Valentina, Escott-Price, Valentina, Giedraitis, Vilmantas, Deramecourt, Vincent, Maier, Wolfgang, Jian, Xueqiu, Pijnenburg, Yolande A L, Andreoni, Simona, Ferrarese, Carlo, Sala Gessica, Zoia, Chiara Paola, Kehoe, Patrick Gavin, Garcia-Ribas, Guillermo, Sánchez-Juan, Pascual, Pastor, Pau, Pérez-Tur, Jordi, Piñol-Ripoll, Gerard, Lopez de Munain, Adolfo, García-Alberca, Jose María, Bullido, María J, Álvarez, Victoria, Lleó, Alberto, Real, Luis M, Mir, Pablo, Medina, Miguel, Scheltens, Philip, Holstege, Henne, Marquié, Marta, Sáez, María Eugenia, Carracedo, Ángel, Amouyel, Philippe, Schellenberg, Gerard D, Williams, Julie, Seshadri, Sudha, van Duijn, Cornelia M, Mather, Karen A, Sánchez-Valle, Raquel, Serrano-Ríos, Manuel, Orellana, Adelina, Tárraga, Lluís, Blennow, Kaj, Huisman, Martijn, Andreassen, Ole A, Posthuma, Danielle, Clarimón, Jordi, Boada, Mercè, van der Flier, Wiesje M, Ramirez, Alfredo, Lambert, Jean-Charles, van der Lee, Sven J, and Ruiz, Agustín
Abstract: Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical trials. We first perform a large genetic association study by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190). Here, we add six variants associated with Alzheimer’s disease risk (near APP, CHRNE, PRKD3/NDUFAF7, PLCG2 and two exonic variants in the SHARPIN gene). Assessment of the polygenic risk score and stratifying by APOE reveal a 4 to 5.5 years difference in median age at onset of Alzheimer’s disease patients in APOE ɛ4 carriers. Because of this study, the underlying mechanisms of APP can be studied to refine the amyloid cascade and the polygenic risk score provides a tool to select individuals at high risk of Alzheimer’s disease.
Published: 2021

42. Biomarker-Based Risk Prediction of Alzheimer’s Disease Dementia in Mild Cognitive Impairment: Psychosocial, Ethical, and Legal Aspects

Author: Rostamzadeh, Ayda, Schwegler, Carolin, Gil-Navarro, Silvia, Rosende-Roca, Maitée, Romotzky, Vanessa, Ortega, Gemma, Canabate, Pilar, Moreno, Mariola, Schmitz-Luhn, Björn, Boada, Merce, Jessen, Frank, Woopen, Christiane, Rostamzadeh, Ayda, Schwegler, Carolin, Gil-Navarro, Silvia, Rosende-Roca, Maitée, Romotzky, Vanessa, Ortega, Gemma, Canabate, Pilar, Moreno, Mariola, Schmitz-Luhn, Björn, Boada, Merce, Jessen, Frank, and Woopen, Christiane
Published: 2021

43. Biomarker-Based Risk Prediction of Alzheimer’s Disease Dementia in Mild Cognitive Impairment: Psychosocial, Ethical, and Legal Aspects

Author: Rostamzadeh, Ayda, primary, Schwegler, Carolin, additional, Gil-Navarro, Silvia, additional, Rosende-Roca, Maitée, additional, Romotzky, Vanessa, additional, Ortega, Gemma, additional, Canabate, Pilar, additional, Moreno, Mariola, additional, Schmitz-Luhn, Björn, additional, Boada, Mercè, additional, Jessen, Frank, additional, and Woopen, Christiane, additional
Published: 2021
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44. Interaction of neuropsychiatric symptoms with APOE e4 and conversion to dementia in MCI patients in a memory clinic

Author: Valero, Sergi, primary, Marquie, Marta, additional, Rojas, Itziar, additional, Moreno, Sonia, additional, Espinosa, Ana, additional, Orellana, Adelina, additional, Montrreal, Laura, additional, Hernandez, Isabel, additional, Mauleon, Ana, additional, Rosende‐Roca, Maitee, additional, Alegret, Montserrat, additional, Pérez‐Cordón, Alba, additional, Ortega, Gemma, additional, Roberto, Natalia, additional, Sanabria, Angela, additional, Abdelnour, Carla, additional, Gil, Silvia, additional, Tartari, Juan Pablo, additional, Vargas, Liliana, additional, Antonio, Ester Esteban‐De, additional, Benaque, Alba, additional, Tarraga, Lluis, additional, Boada, Mercè, additional, and Ruiz, Agustín, additional
Published: 2020
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45. Cognitive Improvement in Patients with Severe Carotid Artery Stenosis after Transcervical Stenting with Protective Flow Reversal

Author: Ortega, Gemma, Álvarez, Beatriz, Quintana, Manuel, Ribó, Marc, Matas, Manuel, and Álvarez-Sabin, José
Published: 2013
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46. Long-Term Treatment with Citicoline May Improve Poststroke Vascular Cognitive Impairment

Author: Alvarez-Sabín, Jose, Ortega, Gemma, Jacas, Carlos, Santamarina, Estevo, Maisterra, Olga, Ribo, Marc, Molina, Carlos, Quintana, Manuel, and Román, Gustavo C.
Published: 2013
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47. Thrombolysis in Anterior Versus Posterior Circulation Strokes: Timing of Recanalization, Ischemic Tolerance, and Other Differences

Author: Pagola, Jorge, Ribo, Marc, Alvarez-Sabin, José, Rubiera, Marta, Santamarina, Estevo, Maisterra, Olga, Delgado-Mederos, Raquel, Ortega, Gemma, Quintana, Manuel, and Molina, Carlos A.
Published: 2011
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48. Caracteristics of a Prospective Cohort of Patients with IPAF (Interstitial Pneumonia with Autoimmune Features) by Neumologists and Reumatologists of Madrid. IPAF-NEREM Study

Author: Nieto Barbero, Mª Asuncion, primary, Vadillo Font, Cristina, additional, Rodríguez-Nieto, Mª Jesús, additional, Sánchez Pernaute, Olga, additional, Romero Bueno, Fredeswinda Isabel, additional, Laporta Hernández, Rosalía, additional, López Muñiz Ballesteros, Belén, additional, Cebrián Martínez, Laura, additional, Río Martínez, Mª Teresa, additional, Mora Ortega, Gemma María, additional, Cobo Ibánez, Tatiana, additional, and Abásolo Alcazar, Lydia, additional
Published: 2020
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49. Is it Time to Reassess the SITS-MOST Criteria for Thrombolysis?: A Comparison of Patients With and Without SITS-MOST Exclusion Criteria

Author: Rubiera, Marta, Ribo, Marc, Santamarina, Estevo, Maisterra, Olga, Delgado-Mederos, Raquel, Delgado, Pilar, Ortega, Gemma, Alvarez-Sabin, Jose, and Molina, Carlos A.
Published: 2009
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50. Amyloid deposition in adults with drug‐resistant temporal lobe epilepsy.

Author: Fonseca, Elena, Lallana, Sofía, Ortega, Gemma, Cano, Amanda, Sarria‐Estrada, Silvana, Pareto, Deborah, Quintana, Manuel, Lorenzo‐Bosquet, Carles, López‐Maza, Samuel, Gifreu, Ariadna, Campos‐Fernández, Daniel, Abraira, Laura, Santamarina, Estevo, Orellana, Adelina, Montrreal, Laura, Puerta, Raquel, Aguilera, Núria, Ramis, Maribel, Rojas, Itziar, and Ruiz, Agustín
Subjects: *TEMPORAL lobe epilepsy, *POSITRON emission tomography, *CINGULATE cortex, *TAU proteins, *PEOPLE with epilepsy
Abstract: Objective Methods Results Significance Pathological amyloid‐β (Aβ) accumulation and hyperphosphorylated tau proteins have been described in resected temporal lobe specimens of epilepsy patients. We aimed to determine cerebrospinal fluid (CSF) Aβ1‐42 and p181‐tau levels and cerebral Aβ deposits on positron emission tomography (Aβ PET) and correlate these findings with cognitive performance in adults with drug‐resistant temporal lobe epilepsy (TLE).In this cross‐sectional study, we enrolled individuals with drug‐resistant TLE who were 25–55 years old. Each participant underwent 18F‐flutemetamol PET, determination of CSF Aβ1‐42, p181‐tau, and total tau, and a comprehensive neuropsychological assessment. We evaluated normalized standard uptake value ratios (SUVRs) for different brain regions on Aβ PET.Thirty patients (mean age = 41.9 ± SD 8.1 years, 57% men) were included. The median disease duration was 9.5 (interquartile range = 4–24) years. Twenty‐six patients (87%) had a clinically significant cognitive impairment on neuropsychological evaluation, 18 (69%) of the amnesic type. On Aβ PET, high uptake was observed in both mesial temporal regions (ipsilateral: SUVR z‐score = .90, 95% confidence interval [CI] = .60–1.20; contralateral: SUVR z‐score = .92, 95% CI = .57–1.27; p < .001), which was higher when compared to SUVR z‐scores in all the remaining regions (p < .001) and in the ipsilateral anterior cingulate (SUVR z‐score = .27, 95% CI = .04–.49, p = .020). No significant deposition was observed in other regions. Seven patients (23%) had low Aβ1‐42 levels, and two (7%) had elevated p181‐tau levels in CSF. Higher p181‐tau levels correlated with poorer verbal fluency (R = −.427, p = .044).Our findings reveal a considerable Aβ deposition in mesial temporal regions and ipsilateral anterior cingulate among adults with drug‐resistant TLE. Additionally, abnormal CSF Aβ1‐42 levels were observed in a significant proportion of patients, and p181‐tau levels were associated with verbal fluency. These results suggest that markers of neuronal damage can be observed in adults with TLE, warranting further investigation. [ABSTRACT FROM AUTHOR]
Published: 2024
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