Search

Your search keyword '"Orr, William C."' showing total 770 results
Start Over Author "Orr, William C."
770 results on '"Orr, William C."'

37. Contributors

Author

Achermann, Peter, primary, Avidan, Alon Y., additional, Åkerstedt, Torbjörn, additional, Allada, Ravi, additional, Allen, Richard P., additional, Ancoli-Israel, Sonia, additional, Armitage, Roseanne, additional, Arnulf, Isabelle, additional, Atwood, Charles W., additional, Baker, Fiona C., additional, Balkin, Thomas J., additional, Balserak, Bilgay Izci, additional, Banks, Siobhan, additional, Barczi, Steven R., additional, Bass, Joseph T., additional, Bassetti, Claudio L., additional, Belenky, Gregory, additional, Benca, Ruth M., additional, Benson, Kathleen L., additional, Bliwise, Donald L., additional, Boeve, Bradley F., additional, Bonnet, Michael H., additional, Borbély, Alexander A., additional, Bornemann, Michel A. Cramer, additional, Buchanan, Peter, additional, Buxton, Orfeu M., additional, Buysse, Daniel J., additional, Cano, Georgina, additional, Cao, Michelle T., additional, Carney, Colleen E., additional, Carskadon, Mary A., additional, Cartwright, Rosalind, additional, Chen, Chien Lin, additional, Chervin, Ronald D., additional, Cistulli, Peter A., additional, Courcoulas, Anita P., additional, Culebras, Antonio, additional, Czeisler, Charles A., additional, Dauvilliers, Yves, additional, Davidson, Alec J., additional, D'Cruz, O'Neill F., additional, de Boer, Tom, additional, Dement, William C., additional, Denis, Ronald, additional, Dijk, Derk-Jan, additional, Dinges, David F., additional, Domhoff, G. William, additional, Douglas, Neil J., additional, Drake, Christopher L., additional, Edinger, Jack D., additional, Elliott, Mark W., additional, Espie, Colin A., additional, Faraco, Juliette H., additional, Feinberg, Irwin, additional, Ferguson, Kathleen A., additional, Ferini-Strambi, Luigi, additional, Franken, Paul, additional, Franklin, Karl A., additional, Gander, Philippa, additional, George, Charles F.P., additional, Givelber, Rachel, additional, Gleeson, Shelagh K., additional, Glovinsky, Paul B., additional, Goel, Namni, additional, Gooley, Joshua J., additional, Graeber, R. Curtis, additional, Grunstein, Ronald, additional, Guardiola-Lemaître, Béatrice, additional, Guilleminault, Christian, additional, Harper, Ronald M., additional, Harvey, Allison G., additional, Hedner, Jan, additional, Heinzer, Raphael C., additional, Herman, John H., additional, Hoffstein, Victor, additional, Hirshkowitz, Max, additional, Horner, Richard L., additional, Hublin, Christer, additional, Hursh, Steven R., additional, Huynh, Nelly T., additional, Javaheri, Shahrokh, additional, Josephson, Mark E., additional, Jun, Jonathan, additional, Kecklund, Göran, additional, Keenan, Sharon, additional, Kräuchi, Kurt, additional, Krueger, James M., additional, Kryger, Meir H., additional, Krystal, Andrew D., additional, Kuna, Samuel T., additional, Kushida, Clete A., additional, Landolt, Hans-Peter, additional, Lanfranchi, Paola A., additional, Lavigne, Gilles, additional, Lee, Kathryn, additional, Leger, Patrick, additional, Li, Christopher, additional, Lichstein, Kenneth L., additional, Lowe, Alan A., additional, MacFarlane, James G., additional, Mahowald, Mark W., additional, Majde, Jeannine A., additional, Malow, Beth A., additional, Manber, Rachel, additional, Manzini, Christiane, additional, Maquet, Pierre, additional, Masa, Juan F., additional, McCrae, Christina S., additional, McDonald, Jennifer, additional, McGinty, Dennis, additional, Means, Melanie K., additional, Mellman, Thomas A., additional, Mendelson, Wallace, additional, Mignot, Emmanuel, additional, Mistlberger, Ralph E., additional, Mittleman, Murray A., additional, Moe, Karen E., additional, Moldofsky, Harvey, additional, Montplaisir, Jacques, additional, Morin, Charles M., additional, Nielsen, Tore, additional, Nieto, F. Javier, additional, Nishino, Seiji, additional, Nofzinger, Eric A., additional, O'Brien, Louise M., additional, O'Hara, Bruce F., additional, Olson, Eric J., additional, O'Malley, Mary B., additional, Orr, William C., additional, Pace-Schott, Edward F., additional, Partinen, Markku, additional, Patel, Dipali, additional, Peever, John H., additional, Peigneux, Philippe, additional, Peker, Yüksel, additional, Perlis, Michael, additional, Perski, Aleksander, additional, Peterson, Michael J., additional, Petit, Dominique, additional, Philip, Pierre, additional, Phillips, Barbara A., additional, Pigeon, Wilfred R., additional, Polotsky, Vsevolod Y., additional, Powell, Nelson B., additional, Punjabi, Naresh M., additional, Quera-Salva, Maria Antonia, additional, Ramsawh, Holly, additional, Ramsey, Kathryn Moynihan, additional, Redline, Susan, additional, Reid, Kathryn J., additional, Remmers, John E., additional, Riley, Robert W., additional, Robert, Dominique, additional, Roehrs, Timothy, additional, Rosenwasser, Alan M., additional, Roth, Thomas, additional, Ruiter, Megan E., additional, Rusak, Benjamin, additional, Sagaspe, Patricia, additional, Samuels, Charles, additional, Sanders, Mark H., additional, Saper, Clifford B., additional, Sarwar, Aliya, additional, Sateia, Michael J., additional, Savard, Josée, additional, Schenck, Carlos H., additional, Schredl, Michael, additional, Schwab, Richard J., additional, Schweitzer, Paula K., additional, Sériès, Frédéric, additional, Sessle, Barry J., additional, Sharafkhaneh, Amir, additional, Shaw, Paul J., additional, Shochat, Tamar, additional, Shouse, Margaret, additional, Siegel, Jerome M., additional, Smith, Carlyle, additional, Smith, Michael T., additional, Somers, Virend K., additional, Spielman, Arthur J., additional, Stein, Murray B., additional, Stickgold, Robert, additional, Stone, Katie L., additional, Stremler, Robyn, additional, Strollo, Patrick J., additional, Szymusiak, Ronald, additional, Taillard, J., additional, Tasali, Esra, additional, Taylor, Daniel J., additional, Teodorescu, Mihai, additional, Terman, Jiuan Su, additional, Terman, Michael, additional, Thorpy, Michael J., additional, Tobler, Irene, additional, Trenkwalder, Claudia, additional, Turek, Fred W., additional, Unruh, Mark L., additional, Van Cauter, Eve, additional, Van Dongen, Hans P.A., additional, Vaughn, Bradley V., additional, Verrier, Richard L., additional, Vila, Bryan, additional, Vitaterna, Martha Hotz, additional, Walsh, James K., additional, Walters, Arthur S., additional, Wamsley, Erin J., additional, Weaver, Terri E., additional, Weil, John V., additional, Weir, Ian D., additional, Wellman, Andrew, additional, Wesensten, Nancy J., additional, White, David P., additional, Wolfson, Amy R., additional, Wright, Kenneth P., additional, Yang, Chien-Ming, additional, Young, Terry, additional, Zadra, Antonio, additional, Zee, Phyllis C., additional, and Zucconi, Marco, additional

Published
2011
Full Text
View/download PDF

42. Effects of menthol on esophageal motility in humans: Studies using high‐resolution manometry.

Author

Lei, Wei‐Yi, Liang, Shu‐Wei, Hung, Jui‐Sheng, Wong, Ming‐Wun, Liu, Tso‐Tsai, Yi, Chih‐Hsun, Lin, Lin, Orr, William C., and Chen, Chien‐Lin

Subjects
ESOPHAGEAL motility, MENTHOL, ESOPHAGOGASTRIC junction, GASTROESOPHAGEAL reflux, HUMAN experimentation
Abstract

Background/aim: The cold receptor, transient receptor potential melastatin 8 (TRPM8), has been reported to be expressed in esophageal vagal afferents. Esophageal infusion of menthol modulates esophageal perception in reflux patients via TRPM8, but the effects of menthol on esophageal motility are not well investigated. This study aimed to test the hypothesis whether the infusion of menthol into the esophagus could affect esophageal peristaltic characteristics. Methods: Eighteen healthy adults (men 13, mean age 27) underwent high‐resolution manometry (HRM) using a catheter with the injection port located in mid‐esophagus. Primary peristalsis was performed with ten wet swallows, while secondary peristalsis was generated by 10 rapid air injections. Two different sessions were randomly performed including acute administration of menthol (3 mM) and the placebo. Results: Menthol significantly decreased upper esophageal (UES) pressure of primary peristalsis than the placebo (p = 0.019). There was no difference in distal contractile integral (p = 0.33), distal latency (p = 0.86), basal lower esophageal sphincter pressure (p = 0.19), or 4‐second integrated relaxation pressure (p = 0.75) between menthol and placebo. Menthol significantly decreased the frequency of secondary peristalsis subsequent to the administration of menthol during rapid injections with 20 mL air (p = 0.04). Conclusions: Intraluminal infusion of menthol reduces UES basal pressure and inhibits peristaltic frequency of secondary peristalsis. The data suggest that the triggering of secondary peristalsis is probably modulated by TRPM8‐sensitive mechanoreceptors; however, the activation of TRPM8 from menthol does not alter esophageal motility following deglutition or distension‐induced secondary peristalsis. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

44. Aging and Neural Control of the GI Tract IV. Clinical and physiological aspects of gastrointestinal motility and aging

Author

Orr, William C. and Chen, C.L.

Subjects
Aging -- Physiological aspects, Aged -- Health aspects, Deglutition disorders -- Research, Biological sciences
Abstract

The gastrointestinal motility changes that occur as a function of age are reviewed herein. Careful attention must be given in any review of aging phenomena to exclude, or at least be cognizant of, the many comorbid conditions that can alter physiological functioning in older adults. The dramatic increase in life expectancy over the past 10-15 years demands that clinicians be aware of the various physiological and clinically relevant changes that occur with age. Gastrointestinal motility changes associated with age are relatively subtle, and in many instances only conflicting data exist. As the older adult population increases, and as the control of disease is improved, much more work needs to be done to understand the true effects of aging on gastrointestinal functioning. gastroesophageal reflux disease; dysphagia; lower esophageal sphincter; incontinence

Published
2002

Catalog

Books, media, physical & digital resources
See catalog results