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Background Short stature, defined as height for age more than 2 standard deviations (SDs) below the population median, is an important indicator of child health. Short stature (often termed stunting) has been widely researched in low- and middle-income countries (LMICs), but less is known about the extent and burden in high-income settings. We aimed to map the prevalence of short stature in children aged 4-5 years in England between 2006 and 2019. Methods and findings We used data from the National Child Measurement Programme (NCMP) for the school years 2006-2007 to 2018-2019. All children attending state-maintained primary schools in England are invited to participate in the NCMP, and heights from a total of 7,062,071 children aged 4-5 years were analysed. We assessed short stature, defined as a height-for-age standard deviation score (SDS) below -2 using the United Kingdom WHO references, by sex, index of multiple deprivation (IMD), ethnicity, and region. Geographic clustering of short stature was analysed using spatial analysis in SaTScan. The prevalence of short stature in England was 1.93% (95% confidence interval (CI) 1.92-1.94). Ethnicity adjusted spatial analyses showed geographic heterogeneity of short stature, with high prevalence clusters more likely in the North and Midlands, leading to 4-fold variation between local authorities (LAs) with highest and lowest prevalence of short stature. Short stature was linearly associated with IMD, with almost 2-fold higher prevalence in the most compared with least deprived decile (2.56% (2.53-2.59) vs. 1.38% (1.35-1.41)). There was ethnic heterogeneity: Short stature prevalence was lowest in Black children (0.64% (0.61-0.67)) and highest in Indian children (2.52% (2.45-2.60)) and children in other ethnic categories (2.57% (2.51-2.64)). Girls were more likely to have short stature than boys (2.09% (2.07-2.10) vs. 1.77% (1.76-1.78), respectively). Short stature prevalence declined over time, from 2.03% (2.01-2.05) in 2006-2010 to 1.82% (1.80-1.84) in 2016-2019. Short stature declined at all levels of area deprivation, with faster declines in more deprived areas, but disparities by IMD quintile were persistent. This study was conducted cross-sectionally at an area level, and, therefore, we cannot make any inferences about the individual causes of short stature. Conclusions In this study, we observed a clear social gradient and striking regional variation in short stature across England, including a North-South divide. These findings provide impetus for further investigation into potential socioeconomic influences on height and the factors underlying regional variation., Author(s): Joanna Orr 1,*, Joseph Freer 1, Joan K. Morris 2, Caroline Hancock 3, Robert Walton 1, Leo Dunkel 1, Helen L. Storr 1, Andrew J. Prendergast 1 Introduction Linear [...]

This article examines the issue of stunting, which refers to below-average height for age, in high-income countries (HICs). While stunting is commonly studied in low- and middle-income countries (LMICs), there is limited research on stunting in HICs. The article presents recent data from the United Kingdom (UK) and discusses the link between stunting and cardiometabolic and neurocognitive outcomes in HICs. The findings suggest that stunting still exists in HICs, particularly in deprived areas, and may be associated with chronic diseases like cardiovascular disease. However, more research is needed to fully understand the impact of stunting in HICs. The article also explores the relationship between childhood growth and health outcomes, such as cardiometabolic disease and cognitive development, and emphasizes the importance of early growth monitoring and public health interventions to address socioeconomic disparities in growth. The authors call for further research to better comprehend these connections and their implications for global health. [Extracted from the article]

Research has often found a U- or J-shaped association between parity and mortality. Many researchers have suggested repeated pregnancy, childbirth, and lactation taxes the body beyond a certain parity level. Available research has concentrated on populations with controlled fertility or historic populations. Ireland presents an opportunity to explore these associations in a modern sample with high fertility. We use data from the Irish Longitudinal Study on Ageing (TILDA) to test whether parity is associated with mortality in women aged 50 years or over (n = 4177). We use Cox proportional hazards models to model survival and adjust for demographics and early life circumstances. We test whether a number of health characteristics mediate these effects. Models were also stratified by birth cohort to test possible cohort effects. Higher parity was associated with lower risk of mortality, even after adjustment for early life and socioeconomic circumstances. This effect was not mediated by current health characteristics. The effects were largely driven by those born between 1931 and 1950. Increasing parity is associated with decreasing mortality risk in this sample. The effects of parity could not be explained through any of the observed health characteristics. These findings are in contrast to much of the literature on this question in similar populations. Lack of fertility control in Ireland may have "selected" healthier women into high parity. Social explanations for these associations should be further explored. [ABSTRACT FROM AUTHOR]

Objectives This study assessed the association between sexual activity, mismatches in the importance attributed to sex within couples, and relationship quality in older Irish adults. Method We used data from the Irish Longitudinal Study on Ageing (TILDA) to derive a scale of subjective relationship strain in married or cohabiting individuals. Negative binomial regression was used to assess the association between relationship strain and sexual activity. Separate models assessed the associations with importance of sex and within-couple mismatch in the importance attributed to sex and whether these associations were independent from sexual activity. Age interactions were tested. Results Sexual activity and within-couple mismatch in the importance attributed to sex were associated with relationship strain. The frequency of sexual activity was consistently associated with less relationship strain for men, but less so for women when the importance attributed to sex was accounted for. Results were largely consistent across age groups for men, but sexual activity and importance of sex varied with age in women. Discussion Frequent sexual activity was associated with less strain within-intimate relationships. For women, this association was weakened when accounting for the importance attributed to sex. Within-couple mismatch in the importance attributed to sex was associated with relationship strain, independent from frequency of sexual activity, for both men and women at all ages. [ABSTRACT FROM AUTHOR]