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844 results on '"Orotate phosphoribosyltransferase"'

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1. A Facile Fluorometric Assay of Orotate Phosphoribosyltransferase Activity Using a Selective Fluorogenic Reaction for Orotic Acid.

2. Conditional disruption of hepatic carbamoyl phosphate synthetase 1 in mice results in hyperammonemia without orotic aciduria and can be corrected by liver-directed gene therapy

3. De novo pyrimidine synthesis is necessary for intestinal colonization of Salmonella Typhimurium in chicks.

4. A Facile Fluorometric Assay of Orotate Phosphoribosyltransferase Activity Using a Selective Fluorogenic Reaction for Orotic Acid

5. Uricase sensitizes hepatocellular carcinoma cells to 5-fluorouracil through uricase-uric acid-UMP synthase axis

6. Biodegradation of the mycotoxin patulin in apple juice by Orotate phosphoribosyltransferase from Rhodotorula mucilaginosa.

7. QM/MM reveals the sequence of substrate binding during OPRT action.

8. Bifunctional activity of fused Plasmodium falciparum orotate phosphoribosyltransferase and orotidine 5′-monophosphate decarboxylase.

10. Salinibacter Ruber: Genomics and Biogeography

11. Expression of thymidylate synthase predicts clinical outcomes of S-1-based chemotherapy in squamous cell lung cancer.

12. Identification of critical genetic variants associated with metabolic phenotypes of the Japanese population

13. Plasmid-based complementation of large deletions in Phaeodactylum tricornutum biosynthetic genes generated by Cas9 editing

14. Metabolic engineering generates a transgene-free safety switch for cell therapy

15. Molecular Dynamics Simulations for Three-Dimensional Structures of Orotate Phosphoribosyltransferases Constructed from a Simplified Amino Acid Set

16. BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals

19. A case-control study of a combination of single nucleotide polymorphisms and clinical parameters to predict clinically relevant toxicity associated with fluoropyrimidine and platinum-based chemotherapy in gastric cancer

20. Correlation between S-1 treatment outcome and expression of biomarkers for refractory thymic carcinoma.

21. Novel mutation in UMPS gene leads to false positive result of DUMPS (genetic disorder) in buffaloes: need for gene sequencing before confirming results of RFLP in new species

22. Biodegradation of the mycotoxin patulin in apple juice by Orotate phosphoribosyltransferase from Rhodotorula mucilaginosa

23. Atypical URA5 gene restriction fragment length polymorphism banding profile in Cryptococcus neoformans strains

24. CRISPR-Cas9 induces point mutation in the mucormycosis fungus Rhizopus delemar

25. Intratumoral Gene Expression of Dihydrofolate Reductase and Folylpoly-C-Glutamate Synthetase Affects the Sensitivity to 5-Fluorouracil in Non-Small Cell Lung Cancer

26. Intratumoral gene expression of 5-fluorouracil pharmacokinetics-related enzymes in stage I and II non-small cell lung cancer patients treated with uracil-tegafur after surgery: A prospective multi-institutional study in Japan.

27. Prognostic significance of thymidylate synthase in postoperative non-small cell lung cancer patients.

28. Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells

29. A unique insertion of low complexity amino acid sequence underlies protein-protein interaction in human malaria parasite orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase.

30. Catalytic site interactions in yeast OMP synthase.

31. Direct Determination of Pseudouridine in RNA by Mass Spectrometry Coupled with Stable Isotope Labeling

32. LncRNA SNORD3A specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression

33. Control of pyrimidine nucleotide formation in Pseudomonas aurantiaca

34. Elucidating the catalytic reaction mechanism of orotate phosphoribosyltransferase by means of X-ray crystallography and computational simulations

35. The inhibition of thymidine phosphorylase can reverse acquired 5FU-resistance in gastric cancer cells

36. QM/MM reveals the sequence of substrate binding during OPRT action

37. The relationship between the expression of thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase, excision repair cross-complementation group 1 and class III β-tubulin, and the therapeutic effect of S-1 or carboplatin plus paclitaxel in non-small-cell lung cancer

38. Antipyrimidine effects of five different pyrimidine de novo synthesis inhibitors in three head and neck cancer cell lines

39. Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase

40. Prediction of clinical outcome of S-1-based chemotherapy for gastric cancer patients.

41. Uricase sensitizes hepatocellular carcinoma cells to 5-fluorouracil through uricase-uric acid-UMP synthase axis.

42. Pyrimidin-2(1H)-ones based inhibitors of Mycobacterium tuberculosis orotate phosphoribosyltransferase

43. Biomarker analysis in patients with advanced gastric cancer treated with S-1 plus cisplatin chemotherapy: orotate phosphoribosyltransferase expression is associated with treatment outcomes.

44. Development of a URA5 integrative cassette for gene disruption in the Candida guilliermondii ATCC 6260 strain

45. Associations of various gene polymorphisms with toxicity in colorectal cancer patients receiving oral uracil and tegafur plus leucovorin: a prospective study.

46. A predictive factor for the response to S-1 plus cisplatin in gastric cancer.

47. Correlations of Clinicopathological Factors with Protein Expression Levels of Thymidylate Synthase, Dihydropyrimidine Dehydrogenase and Orotate Phosphoribosyltransferase in Colorectal Cancer.

48. Structure of orotate phosphoribosyltransferase from the caries pathogen Streptococcus mutans.

49. Kinetic benefits and thermal stability of orotate phosphoribosyltransferase and orotidine 5′-monophosphate decarboxylase enzyme complex in human malaria parasite Plasmodium falciparum

50. High Orotate Phosphoribosyltransferase Gene Expression Predicts Complete Response to Chemoradiotherapy in Patients with Squamous Cell Carcinoma of the Esophagus.

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