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1. Search for the 6$\alpha$ condensed state in $^{24}$Mg using the $^{12}\rm{C}+{}^{12}\rm{C}$ scattering

Author

Fujikawa, Y., Kawabata, T., Adachi, S., Enyo, S., Furuno, T., Hijikata, Y., Himi, K., Hirose, K., Honda, Y., Inaba, K., Makii, H., Miyamoto, K., Murata, M., Nishio, K., Okamoto, S., Orlandi, R., Sakanashi, K., Suzaki, F., Tsuji, S., Yahiro, K., and Zenihiro, J.

Subjects
Nuclear Experiment, Nuclear Theory
Abstract

We searched for the 6$\alpha$-condensed state in $^{24}$Mg by measuring the $^{12}\rm{C}+{}^{12}\rm{C}$ scattering with the SAKRA Si detector array at $E_\rm{cm}$ = 17.5-25.0 MeV. By using the invariant-mass method for the detected 3$\alpha$ particles, the inclusive cross sections for the $^{12}\rm{C}+{}^{12}\rm{C}\to{}^{12}\rm{C}(0^+_2)+X$ and $^{12}\rm{C}(3^-_1)+X$ reactions were determined. In addition, the missing-mass spectroscopy was successfully utilized to determine the excitation energy of the residual $^{12}\rm{C}$ nucleus and the exclusive cross sections for the $^{12}\rm{C}+{}^{12}\rm{C}\to{}^{12}\rm{C}(0^+_2)+{}^{12}\rm{C}(0^+_1)$, $^{12}\rm{C}(0^+_2)+{}^{12}\rm{C}(2^+_1)$, and $^{12}\rm{C}(0^+_2)+{}^{12}\rm{C}(0^+_2)$ reactions. In both the inclusive $^{12}\rm{C}(0^+_2)+X$ channel and the exclusive $^{12}\rm{C}(0^+_2)+{}^{12}\rm{C}(0^+_1)$ channel, the cross section peaked at $E_rm{cm}$ = 19.4 MeV, which correspond to the excitation energy of $E_x$ = 33.3 MeV in $^{24}\rm{Mg}$. This 19.4-MeV state is a candidate for the 6$\alpha$-condensed state because of the agreement of the excitation energy with the theoretical value and its decay property. In the exclusive $^{12}\rm{C}(0^+_2)+{}^{12}\rm{C}(0^+_2)$ channel, a broad state was observed at $E_\rm{cm}$ = 22.5 MeV, which correspond to the excitation energy of $E_x$ = 36.4 MeV in $^{24}\rm{Mg}$. From the angular distribution of the differential cross section, the spin and parity of this 22.5-MeV state was assigned to be $4^+$. In addition, a $2^+$ state was suggested at the low-energy side of the 22.5-MeV state. Because their excitation energies are higher than the theoretical value of the 6$\alpha$-condensed state, these states might be excited states of the 6$\alpha$-condensed state such as the $2^+_2$ and $4^+_1$ states in $^{12}\rm{C}$., Comment: 8 pages, 6 figures

Published
2023
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2. Axial and triaxial degrees of freedom in 72Zn

Author

Hellgartner, S, Mücher, D, Wimmer, K, Bildstein, V, Egido, JL, Gernhäuser, R, Krücken, R, Nowak, AK, Zielińska, M, Bauer, C, Benito, MLL, Bottoni, S, De Witte, H, Elseviers, J, Fedorov, D, Flavigny, F, Illana, A, Klintefjord, M, Kröll, T, Lutter, R, Marsh, B, Orlandi, R, Pakarinen, J, Raabe, R, Rapisarda, E, Reichert, S, Reiter, P, Scheck, M, Seidlitz, M, Siebeck, B, Siesling, E, Steinbach, T, Stora, T, Vermeulen, M, Voulot, D, Warr, N, and Wenander, FJC

Subjects
Mathematical Physics, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics
Abstract

The unstable N=42 nucleus 72Zn has been studied using multiple safe Coulomb excitation in inverse kinematics. The experiment was performed at the REX-ISOLDE facility at CERN making first use of the silicon detector array C-REX in combination with the γ-ray spectrometer Miniball. The high angular coverage of C-REX allowed to determine the reduced transition strengths for the decay of the yrast 01+, 21+ and 41+ as well as of the 02+ and 22+ states in 72Zn. The quadrupole moments of the 21+, 41+ and 22+ states were extracted. Using model independent quadrupole invariants, the ground state of 72Zn was found to have an average deformation in the γ degree of freedom close to maximum triaxiality. In comparison to experimental data in zinc isotopes with N

Published
2023

3. Symmetries in mirror nuclei 31S and 31P

Author

Tonev D., de Angelis G., Goutev N., Iliev S., Orlandi R., Deloncle I., Demerdjiev A., Gadea A., Geleva E., He C., Laftchiev H., Lunardi S., Marginean N., Nikolov A., Pavlov P., Pantaleev I.L., Penttilä H., Recchia F., Sahin E., Singh R.P., Slavchev B., Wirth H.–F., and Yavahchova M.S.

Subjects
Physics, QC1-999
Abstract

Excited states in mirror nuclei 31S and 31P were populated in the 1n and 1p exit channels, respectively, of the reaction 20Ne + 12C. The beam of 20Ne, with an energy of 33 MeV, was delivered for the first time by the Piave-Alpi accelerator of the Laboratori Nazionali di Legnaro. Angular correlations of coincident pairs and Doppler-shift attenuation lifetime measurements in 31S and 31P were performed using the multidetector array GASP in conjunction with the EUCLIDES charged particle detector. A comparison of the determined B(E1) strengths of the analog mirror 7/2- → 5/2+ transitions indicates the presence of a violation of isospin symmetry.

Published
2018
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4. The $^{59}$Fe(n, {\gamma})$^{60}$Fe Cross Section from the Surrogate Ratio Method and Its Effect on the $^{60}$Fe Nucleosynthesis

Author

Yan, S. Q., Li, X. Y., Nishio, K., Lugaro, M., Li, Z. H., Makii, H., Pignatari, M., Wang, Y. B., Orlandi, R., Hirose, K., Tsukada, K., Mohr, P., Li, G. S., Wang, J. G., Gao, B. S., Han, Y. L., Guo, B., Li, Y. J., Shen, Y. P., Sato, T. K., Ito, Y., Suzaki, F., Su, J., Yang, Y. Y., Wang, J. S., Ma, J. B., Ma, P., Bai, Z., Xu, S. W., Ren, J., Fan, Q. W., Zeng, S., Han, Z. Y., Nan, W., Nan, W. K., Chen, C., Lian, G., Hu, Q., Duan, F. F., Jin, S. Y., Tang, X. D., and Liu, W. P.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

The long-lived $^{60}$Fe (with a half-life of 2.62 Myr) is a crucial diagnostic of active nucleosynthesis in the Milky Way galaxy and in supernovae near the solar system. The neutron-capture reaction $^{59}$Fe(n,$\gamma$)$^{60}$Fe on $^{59}$Fe (half-life = 44.5 days) is the key reaction for the production of $^{60}$Fe in massive stars. This reaction cross section has been previously constrained by the Coulomb dissociation experiment, which offered partial constraint on the $E$1 $\gamma$-ray strength function but a negligible constraint on the $M$1 and $E$2 components. In this work, for the first time, we use the surrogate ratio method to experimentally determine the $^{59}$Fe(n,$\gamma$)$^{60}$Fe cross sections in which all the components are included. We derived a Maxwellian-averaged cross section of 27.5 $\pm$ 3.5 mb at $kT$= 30 keV and 13.4 $\pm$ 1.7 mb at $kT$= 90 keV, roughly 10 - 20% higher than previous estimates. We analyzed the impact of our new reaction rates in nucleosynthesis models of massive stars and found that uncertainties in the production of $^{60}$Fe from the $^{59}$Fe(n,$\gamma$)$^{60}$Fe rate are at most of 25%. We conclude that stellar physics uncertainties now play a major role in the accurate evaluation of the stellar production of $^{60}$Fe., Comment: 9 pages with 6 figures

Published
2021
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5. Quadrupole collectivity in neutron-rich Cd isotopes

Author

Bönig S., Ilieva S., Kröll T., Scheck M., Balabanski D., Bauer C., Blazhev A., Bloch T., Deleanu D., Diriken J., Fernier P., Gernhäuser R., Hadyńska-Kęk K., Jungclaus A., Lutter R., Negret A., Nowak K., Orlandi R., Pakarinen J., Rainovski G., Rodríguez T.R., Schmid M. von, Seidlitz M., Siebeck B., Simpson G.S., Sisón A. Illana, Stegmann R., Stora T., Thirolf P.G., Thürauf M., Vermeulen M.J., Voulot D., Warr N., Wenander F., and Witte H. De

Subjects
Physics, QC1-999
Abstract

The investigation of the excitation energies of the 21+ –states in the neutron-rich Cd isotopes shows an irregular behaviour when approaching the neutron shell-closure at N = 82. The energy of the 21+–state in 128Cd is lower than the one in 126Cd. The transition strength B(E2, 0gs+ → 21+) in the even isotopes 122−128Cd was measured in Coulomb excitation experiments with the high-purity germanium detector array MINIBALL at REXISOLDE (CERN). The values for 122,124Cd coincide with beyond-mean-field calculations with a resultant prolate deformation, whereas 126,128Cd are better described by shell-model calculations.

Published
2014
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6. Isomer and beta decay spectroscopy in the 132Sn region with EURICA

Author

Jungclaus A., Simpson G.S., Gey G., Taprogge J., Nishimura S., Doornenbal P., Lorusso G., Söderström P.-A., Sumikama T., Xu Z., Baba H., Browne F., Fukuda N., Inabe N., Isobe T., Jung H.S., Kameda D., Kim G.D., Kim Y.-K., Kojouharov I., Kubo T., Kurz N., Kwon Y.K., Li Z., Sakurai H., Schaffner H., Suzuki H., Takeda H., Vajta Z., Watanabe H., Wu J., Yagi A., Yoshinaga K., Bönig S., Daugas J.-M., Drouet F., Gernhäuser R., Ilieva S., Kröll T., Montaner-Pizá A., Moschner K., Mücher D., Nishibata H., Orlandi R., Steiger K., and Wendt A.

Subjects
Physics, QC1-999
Abstract

The first EURICA campaign with high intensity Uranium beams took place at RIKEN in November/December 2012. Within this campaign experiment NP1112-RIBF85 was performed dedicated to the study of the isomeric and beta decays of neutronrich Cd, In, Sn and Sb isotopes towards and beyond the N=82 neutron shell closure. In this contribution we present a first status report of the analysis of the extensive data set obtained in this experiment.

Published
2014
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7. Magnetic moment measurement in 72Zn using the Transient Field technique and Coulomb excitation in inverse kinematics

Author

Illana Sisón A., Jungclaus A., Orlandi R., Perea A., Briz J.A., Bauer C., Gernhäuser R., Leske J., Mücher D., Pakarinen J., Pietralla N., Rajabali M.M., Seiler D., and Stahl C.

Subjects
Physics, QC1-999
Abstract

The g factor of the first excited 2+ state of 72Zn has been measured using the Low Velocity Transient Field (LVTF) technique in combination with Coulomb excitation in inverse kinematics. The aim of the experiment was to test the viability of this method when applied to short-lived radioactive ISOL beams, in particular in comparison to the alternative High Velocity Transient Field (HVTF) technique using fragment beams. The result obtained for g(2+) in 72Zn in the present experiment follows the trend observed for the lighter stables Zn isotopes.

Published
2014
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10. First observation of the competing fission modes in the neutron-deficient sub-lead region

Author

Tsekhanovich, I., Andreyev, A. N., Nishio, K., Denis-Petit, D., Hirose, K., Makii, H., Matheson, Z., Morimoto, K., Morita, K., Nazarewicz, W., Orlandi, R., Sadhukhan, J., Tanaka, T., Vermeulen, M., and Warda, M.

Subjects
Nuclear Experiment
Abstract

Fragment mass distributions from fission of excited compound nucleus $^{178}$Pt have been deduced from the measured fragment velocities. The $^{178}$Pt nucleus was created at the JAEA tandem facility in a complete fusion reaction $^{36}$Ar + $^{142}$Nd, at beam energies of 155, 170 and 180 MeV. The data are indicative of a mixture of the mass-asymmetric and mass-symmetric fission modes associated with higher and lower total kinetic energies of the fragments, respectively. The measured fragment yields are dominated by asymmetric mass splits, with the symmetric mode contributing at the level of $\approx1/3$. This constitutes the first observation of a multimodal fission in the sub-lead region. Most probable experimental fragment-mass split of the asymmetric mode, $A_{L}/A_{H}\approx 79/99$, is well reproduced by nuclear density functional theory using the UNEDF1-HFB and D1S potentials. The symmetric mode is associated by theory with very elongated fission fragments, which is consistent with the observed total kinetic energy/fragment mass correlation., Comment: 6 pages, 4 figures

Published
2018
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11. Is Seniority a Partial Dynamic Symmetry in the First $\nu g_{9/2}$ Shell?

Author

Morales, A. I., Benzoni, G., Watanabe, H., de Angelis, G., Nishimura, S., Coraggio, L., Gargano, A., Itaco, N., Otsuka, T., Tsunoda, Y., Van Isacker, P., Browne, F., Daido, R., Doornenbal, P., Fang, Y., Lorusso, G., Patel, Z., Rice, S., Sinclair, L., Söderström, P. -A., Sumikama, T., Wu, J., Xu, Z. Y., Yagi, A., Yokoyama, R., Baba, H., Avigo, R., Garrote, F. L. Bello, Blasi, N., Bracco, A., Bruce, A. M., Camera, F., Ceruti, S., Crespi, F. C. L., Delattre, M. -C., Dombradi, Zs., Gottardo, A., Isobe, T., Kojouharov, I., Kurz, N., Kuti, I., Lalkovski, S., Matsui, K., Melon, B., Mengoni, D., Miyazaki, T., Modamio-Hoybjor, V., Momiyama, S., Napoli, D. R., Niikura, M., Orlandi, R., Podolyák, Zs., Regan, P. H., Sakurai, H., Sahin, E., Sohler, D., Schaffner, H., Taniuchi, R., Taprogge, J., Vajta, Zs., Valiente-Dobón, J. J., Wieland, O., and Yalcinkaya, M.

Subjects
Nuclear Experiment, Nuclear Theory
Abstract

The low-lying structures of the midshell $\nu g_{9/2}$ Ni isotopes $^{72}$Ni and $^{74}$Ni have been investigated at the RIBF facility in RIKEN within the EURICA collaboration. Previously unobserved low-lying states were accessed for the first time following $\beta$ decay of the mother nuclei $^{72}$Co and $^{74}$Co. As a result, we provide a complete picture in terms of the seniority scheme up to the first $(8^+)$ levels for both nuclei. The experimental results are compared to shell-model calculations in order to define to what extent the seniority quantum number is preserved in the first neutron $g_{9/2}$ shell. We find that the disappearance of the seniority isomerism in the $(8^+_1)$ states can be explained by a lowering of the seniority-four $(6^+)$ levels as predicted years ago. For $^{74}$Ni, the internal de-excitation pattern of the newly observed $(6^+_2)$ state supports a restoration of the normal seniority ordering up to spin $J=4$. This property, unexplained by the shell-model calculations, is in agreement with a dominance of the single-particle spherical regime near $^{78}$Ni.

Published
2017
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12. The 95zr(n, gamma)96zr cross section from the surrogate ratio method and its effect on the s-process nucleosynthesis

Author

Yan, S. Q., Li, Z. H., Wang, Y. B., Nishio, K., Lugaro, M., Karakas, A. I., Makii, H., Mohr, P., Su, J., Li, Y. J., Nishinaka, I., Hirose, K., Han, Y. L., Orlandi, R., Shen, Y. P., Guo, B., Zeng, S., Lian, G., Chen, Y. S., and Liu, W. P.

Subjects
Nuclear Experiment
Abstract

The 95Zr(n,gamma)96Zr reaction cross section is crucial in the modelling of s-process nucleosynthesis in asymptotic giant branch stars because it controls the operation of the branching point at the unstable 95Zr and the subsequent production of 96Zr. We have carried out the measurement of the 94Zr(18O,16O) and 90Zr(18O,16O) reactions and obtained the gamma-decay probability ratio of 96Zr* and 92Zr* to determine the 95Zr(n,gamma)96Zr reaction cross sections with the surrogate ratio method. Our deduced maxwellian-averaged cross section of 66+-16 mb at 30 keV is close to the value recommended by Bao et al. (2000), but 30% and more than a factor of two larger than the values proposed by Toukan & Kappeler (1990) and Lugaro et al. (2014), respectively, and routinely used in s-process models. We tested the new rate in stellar models with masses between 2 and 6 Msun and metallicities 0.014 and 0.03. The largest changes - up 80% variations in 96Zr - are seen in models of mass 3-4 Msun, where the 22Ne neutron source is mildly activated. The new rate can still provide a match to data from meteoritic stardust silicon carbide grains, provided the maximum mass of the parent stars is below 4 Msun, for a metallicity of 0.03., Comment: 10 pages, 6 figures, accepted for publication in ApJ

Published
2017
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13. Spectroscopy of Neutron-rich Fe Isotopes Populated in the \(^{70}\)Zn+\(^{238}\)U Reaction

Author

Benito, J., primary, Lenzi, S.M., additional, Recchia, F., additional, Axiotis, M., additional, Aydin, S., additional, Bazzacco, D., additional, Benzoni, G., additional, Bizzeti, P.G., additional, Bizzeti-Sona, A.M., additional, Bracco, A., additional, Broda, R., additional, Bucurescu, D., additional, Caurier, E., additional, Corradi, L., additional, de Angelis, G., additional, Della Vedova, F., additional, Farnea, E., additional, Fornal, B., additional, Fioretto, E., additional, Gadea, A., additional, Gottardo, A., additional, Ionescu-Bujor, M., additional, Iordachescu, A., additional, Leoni, S., additional, Lunardi, S., additional, Mărginean, N., additional, Mărginean, R., additional, Mason, P., additional, Menegazzo, R., additional, Mengoni, D., additional, Million, B., additional, Montagnoli, G., additional, Napoli, D.R., additional, Nowacki, F., additional, Orlandi, R., additional, Pollarolo, G., additional, Poves, A., additional, Sahin, E., additional, Scarlassara, F., additional, Singh, R.P., additional, Stefanini, A.M., additional, Szilner, S., additional, Ur, C.A., additional, Valiente-Dobón, J.J., additional, and Wieland, O., additional

Published
2024
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14. Spectroscopy of 46Ar by the (t,p) two-neutron transfer reaction

Author

Nowak, K., Wimmer, K., Hellgartner, S., Mücher, D., Bildstein, V., Diriken, J., Elseviers, J., Gaffney, L. P., Gernhäuser, R., Iwanicki, J., Johansen, J. G., Huyse, M., Konki, J., Krücken, T. Kröll R., Lutter, R., Orlandi, R., Pakarinen, J., Raabe, R., Reiter, P., Roger, T., Schrieder, G., Seidlitz, M., Sorlin, O., Van Duppen, P., Warr, N., De Witte, H., and Zielinska, M.

Subjects
Nuclear Experiment, Nuclear Theory
Abstract

States in the $N=28$ nucleus $^{46}$Ar have been studied by a two-neutron transfer reaction at REX-ISOLDE (CERN). A beam of radioactive $^{44}$ at an energy of 2.16~AMeV and a tritium loaded titanium target were used to populate $^{46}$ by the t($^{44}$,p) two-neutron transfer reaction. Protons emitted from the target were identified in the T-REX silicon detector array. The excitation energies of states in $^{46}$ have been reconstructed from the measured angles and energies of recoil protons. Angular distributions for three final states were measured and based on the shape of the differential cross section an excited state at 3695~keV has been identified as $J^\pi = 0^+$. The angular differential cross section for the population of different states are compared to calculations using a reaction model employing both sequential and direct transfer of two neutrons. Results are compared to shell model calculations using state-of-the-art effective interactions., Comment: 10 pages, 12 figures, PRC accepted

Published
2016
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15. Collectivity in the light radon nuclei measured directly via Coulomb excitation

Author

Gaffney, L. P., Robinson, A. P., Jenkins, D. G., Andreyev, A. N., Bender, M., Blazhev, A., Bree, N., Bruyneel, B., Butler, P. A., Cocolios, T. E., Davinson, T., Deacon, A. N., De Witte, H., DiJulio, D., Diriken, J., Ekström, A., Fransen, Ch., Freeman, S. J., Geibel, K., Grahn, T., Hadinia, B., Hass, M., Heenen, P. -H., Hess, H., Huyse, M., Jakobsson, U., Kesteloot, N., Konki, J., Kröll, Th., Kumar, V., Ivanov, O., Martin-Haugh, S., Mücher, D., Orlandi, R., Pakarinen, J., Petts, A., Peura, P., Rahkila, P., Reiter, P., Scheck, M., Seidlitz, M., Singh, K., Smith, J. F., Van de Walle, J., Van Duppen, P., Voulot, D., Wadsworth, R., Warr, N., Wenander, F., Wimmer, K., Wrzosek-Lipska, K., and Zielińska, M.

Subjects
Nuclear Experiment
Abstract

Background: Shape coexistence in heavy nuclei poses a strong challenge to state-of-the-art nuclear models, where several competing shape minima are found close to the ground state. A classic region for investigating this phenomenon is in the region around $Z=82$ and the neutron mid-shell at $N=104$. Purpose: Evidence for shape coexistence has been inferred from $\alpha$-decay measurements, laser spectroscopy and in-beam measurements. While the latter allow the pattern of excited states and rotational band structures to be mapped out, a detailed understanding of shape coexistence can only come from measurements of electromagnetic matrix elements. Method: Secondary, radioactive ion beams of $^{202}$Rn and $^{204}$Rn were studied by means of low-energy Coulomb excitation at the REX-ISOLDE facility in CERN. Results: The electric-quadrupole ($E2$) matrix element connecting the ground state and first-excited $2^{+}_{1}$ state was extracted for both $^{202}$Rn and $^{204}$Rn, corresponding to ${B(E2;2^{+}_{1} \to 2^{+}_{1})=29^{+8}_{-8}}$ W.u. and $43^{+17}_{-12}$ W.u., respectively. Additionally, $E2$ matrix elements connecting the $2^{+}_{1}$ state with the $4^{+}_{1}$ and $2^{+}_{2}$ states were determined in $^{202}$Rn. No excited $0^{+}$ states were observed in the current data set, possibly due to a limited population of second-order processes at the currently-available beam energies. Conclusions: The results are discussed in terms of collectivity and the deformation of both nuclei studied is deduced to be weak, as expected from the low-lying level-energy schemes. Comparisons are also made to state-of-the-art beyond-mean-field model calculations and the magnitude of the transitional quadrupole moments are well reproduced., Comment: 12 pages, 14 figures

Published
2015
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17. Search for the 6α condensed state in 24Mg using the 12C+12C scattering

Author

Fujikawa, Y., primary, Kawabata, T., additional, Adachi, S., additional, Enyo, S., additional, Furuno, T., additional, Hijikata, Y., additional, Himi, K., additional, Hirose, K., additional, Honda, Y., additional, Inaba, K., additional, Makii, H., additional, Miyamoto, K., additional, Murata, M., additional, Nishio, K., additional, Okamoto, S., additional, Orlandi, R., additional, Sakanashi, K., additional, Suzaki, F., additional, Tsuji, S., additional, Yahiro, K., additional, and Zenihiro, J., additional

Published
2023
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20. Isospin Symmetry violation in mirror E1 transitions: Coherent contributions from the Giant Isovector Monopole Resonance in 67As - 67Se

Author

Bizzeti, P. G., de Angelis, G., Lenzi, S. M., and Orlandi, R.

Subjects
Nuclear Theory, Nuclear Experiment
Abstract

The assumption of an exact isospin symmetry would imply equal strengths for mirror E1 transitions (at least, in the long-wavelength limit). Actually, large violations of this symmetry rule have been indicated by a number of experimental results, the last of which is the 67As - 67Se doublet investigated at GAMMASPHERE. Here, we examine in detail various possible origins of the observed asymmetry. The coherent effect of Coulomb-induced mixing with the high-lying Giant Isovector Monopole Resonance is proposed as the most probable process to produce a large asymmetry in the E1 transitions, with comparatively small effect on the other properties of the parent and daughter levels., Comment: 14 pages, 2 figures

Published
2012
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21. AGATA - Advanced Gamma Tracking Array

Author

Akkoyun, S., Algora, A., Alikhani, B., Ameil, F., de Angelis, G., Arnold, L., Astier, A., Ataç, A., Aubert, Y., Aufranc, C., Austin, A., Aydin, S., Azaiez, F., Badoer, S., Balabanski, D. L., Barrientos, D., Baulieu, G., Baumann, R., Bazzacco, D., Beck, F. A., Beck, T., Bednarczyk, P., Bellato, M., Bentley, M. A., Benzoni, G., Berthier, R., Berti, L., Beunard, R., Bianco, G. Lo, Birkenbach, B., Bizzeti, P. G., Bizzeti-Sona, A. M., Blanc, F. Le, Blasco, J. M., Blasi, N., Bloor, D., Boiano, C., Borsato, M., Bortolato, D., Boston, A. J., Boston, H. C., Bourgault, P., Boutachkov, P., Bouty, A., Bracco, A., Brambilla, S., Brawn, I. P., Brondi, A., Broussard, S., Bruyneel, B., Bucurescu, D., Burrows, I., Bürger, A., Cabaret, S., Cahan, B., Calore, E., Camera, F., Capsoni, A., Carrió, F., Casati, G., Castoldi, M., Cederwall, B., Cercus, J. -L., Chambert, V., Chambit, M. El, Chapman, R., Charles, L., Chavas, J., Clément, E., Cocconi, P., Coelli, S., Coleman-Smith, P. J., Colombo, A., Colosimo, S., Commeaux, C., Conventi, D., Cooper, R. J., Corsi, A., Cortesi, A., Costa, L., Crespi, F. C. L., Cresswell, J. R., Cullen, D. M., Curien, D., Czermak, A., Delbourg, D., Depalo, R., Descombes, T., Désesquelles, P., Detistov, P., Diarra, C., Didierjean, F., Dimmock, M. R., Doan, Q. T., Domingo-Pardo, C., Doncel, M., Dorangeville, F., Dosme, N., Drouen, Y., Duchêne, G., Dulny, B., Eberth, J., Edelbruck, P., Egea, J., Engert, T., Erduran, M. N., Ertürk, S., Fanin, C., Fantinel, S., Farnea, E., Faul, T., Filliger, M., Filmer, F., Finck, Ch., de France, G., Gadea, A., Gast, W., Geraci, A., Gerl, J., Gernhäuser, R., Giannatiempo, A., Giaz, A., Gibelin, L., Givechev, A., Goel, N., González, V., Gottardo, A., Grave, X., Grȩbosz, J., Griffiths, R., Grint, A. N., Gros, P., Guevara, L., Gulmini, M., Görgen, A., Ha, H. T. M., Habermann, T., Harkness, L. J., Harroch, H., Hauschild, K., He, C., Hernández-Prieto, A., Hervieu, B., Hess, H., Hüyük, T., Ince, E., Isocrate, R., Jaworski, G., Johnson, A., Jolie, J., Jones, P., Jonson, B., Joshi, P., Judson, D. S., Jungclaus, A., Kaci, M., Karkour, N., Karolak, M., Kaşkaş, A., Kebbiri, M., Kempley, R. S., Khaplanov, A., Klupp, S., Kogimtzis, M., Kojouharov, I., Korichi, A., Korten, W., Kröll, Th., Krücken, R., Kurz, N., Ky, B. Y., Labiche, M., Lafay, X., Lavergne, L., Lazarus, I. H., Leboutelier, S., Lefebvre, F., Legay, E., Legeard, L., Lelli, F., Lenzi, S. M., Leoni, S., Lermitage, A., Lersch, D., Leske, J., Letts, S. C., Lhenoret, S., Lieder, R. M., Linget, D., Ljungvall, J., Lopez-Martens, A., Lotodé, A., Lunardi, S., Maj, A., van der Marel, J., Mariette, Y., Marginean, N., Marginean, R., Maron, G., Mather, A. R., Mȩczyński, W., Mendéz, V., Medina, P., Melon, B., Menegazzo, R., Mengoni, D., Merchan, E., Mihailescu, L., Michelagnoli, C., Mierzejewski, J., Milechina, L., Million, B., Mitev, K., Molini, P., Montanari, D., Moon, S., Morbiducci, F., Moro, R., Morrall, P. S., Möller, O., Nannini, A., Napoli, D. R., Nelson, L., Nespolo, M., Ngo, V. L., Nicoletto, M., Nicolini, R., Noa, Y. Le, Nolan, P. J., Norman, M., Nyberg, J., Obertelli, A., Olariu, A., Orlandi, R., Oxley, D. C., Özben, C., Ozille, M., Oziol, C., Pachoud, E., Palacz, M., Palin, J., Pancin, J., Parisel, C., Pariset, P., Pascovici, G., Peghin, R., Pellegri, L., Perego, A., Perrier, S., Petcu, M., Petkov, P., Petrache, C., Pierre, E., Pietralla, N., Pietri, S., Pignanelli, M., Piqueras, I., Podolyak, Z., Pouhalec, P. Le, Pouthas, J., Pugnére, D., Pucknell, V. F. E., Pullia, A., Quintana, B., Raine, R., Rainovski, G., Ramina, L., Rampazzo, G., La Rana, G., Rebeschini, M., Recchia, F., Redon, N., Reese, M., Reiter, P., Regan, P. H., Riboldi, S., Richer, M., Rigato, M., Rigby, S., Ripamonti, G., Robinson, A. P., Robin, J., Roccaz, J., Ropert, J. -A., Rossé, B., Alvarez, C. Rossi, Rosso, D., Rubio, B., Rudolph, D., Saillant, F., Şahin, E., Salomon, F., Salsac, M. -D., Salt, J., Salvato, G., Sampson, J., Sanchis, E., Santos, C., Schaffner, H., Schlarb, M., Scraggs, D. P., Seddon, D., Şenyiğit, M., Sigward, M. -H., Simpson, G., Simpson, J., Slee, M., Smith, J. F., Sona, P., Sowicki, B., Spolaore, P., Stahl, C., Stanios, T., Stefanova, E., Stézowski, O., Strachan, J., Suliman, G., Söderström, P. -A., Tain, J. L., Tanguy, S., Tashenov, S., Theisen, Ch., Thornhill, J., Tomasi, F., Toniolo, N., Touzery, R., Travers, B., Triossi, A., Tripon, M., Tun-Lanoë, K. M. M., Turcato, M., Unsworth, C., Ur, C. A., Valiente-Dobon, J. J., Vandone, V., Vardaci, E., Venturelli, R., Veronese, F., Veyssiere, Ch., Viscione, E., Wadsworth, R., Walker, P. M., Warr, N., Weber, C., Weisshaar, D., Wells, D., Wieland, O., Wiens, A., Wittwer, G., Wollersheim, H. J., Zocca, F., Zamfir, N. V., Ziȩbliński, M., and Zucchiatti, A.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

The Advanced GAmma Tracking Array (AGATA) is a European project to develop and operate the next generation gamma-ray spectrometer. AGATA is based on the technique of gamma-ray energy tracking in electrically segmented high-purity germanium crystals. This technique requires the accurate determination of the energy, time and position of every interaction as a gamma ray deposits its energy within the detector volume. Reconstruction of the full interaction path results in a detector with very high efficiency and excellent spectral response. The realization of gamma-ray tracking and AGATA is a result of many technical advances. These include the development of encapsulated highly-segmented germanium detectors assembled in a triple cluster detector cryostat, an electronics system with fast digital sampling and a data acquisition system to process the data at a high rate. The full characterization of the crystals was measured and compared with detector-response simulations. This enabled pulse-shape analysis algorithms, to extract energy, time and position, to be employed. In addition, tracking algorithms for event reconstruction were developed. The first phase of AGATA is now complete and operational in its first physics campaign. In the future AGATA will be moved between laboratories in Europe and operated in a series of campaigns to take advantage of the different beams and facilities available to maximize its science output. The paper reviews all the achievements made in the AGATA project including all the necessary infrastructure to operate and support the spectrometer., Comment: This version contains a correction of a typing error in the caption of Fig. 2. The DOI to the article published in Nucl. Instr. Meth A was also added

Published
2011
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22. Discovery of the shape coexisting 0+ state in 32Mg by a two neutron transfer reaction

Author

Wimmer, K., Kröll, T., Krücken, R., Bildstein, V., Gernhäuser, R., Bastin, B., Bree, N., Diriken, J., Van Duppen, P., Huyse, M., Patronis, N., Vermaelen, P., Voulot, D., Van de Walle, J., Wenander, F., Fraile, L. M., Chapman, R., Hadinia, B., Orlandi, R., Smith, J. F., Lutter, R., Thirolf, P. G., Labiche, M., Blazhev, A., Kalkühler, M., Reiter, P., Seidlitz, M., Warr, N., Macchiavelli, A. O., Jeppesen, H. B., Fiori, E., Georgiev, G., Schrieder, G., Gupta, S. Das, Bianco, G. Lo, Nardelli, S., Butterworth, J., Johansen, J., and Riisager, K.

Subjects
Nuclear Experiment
Abstract

The Island of Inversion nucleus 32Mg has been studied by a (t,p) two neutron transfer reaction in inverse kinematics at REX-ISOLDE. The shape coexistent excited 0+ state in 32Mg has been identified by the characteristic angular distribution of the protons of the DeltaL = 0 transfer. The excitation energy of 1058 keV is much lower than predicted by any theoretical model. The low gamma-ray intensity observed for the decay of this 0+ state indicates a lifetime of more than 10 ns. Deduced spectroscopic amplitudes are compared with occupation numbers from shell model calculations., Comment: Phys. Rev. Lett. accepted for publication http://prl.aps.org

Published
2010
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25. Post-intubation iatrogenic tracheobronchial injuries: The state of art

Author

Passera E., Orlandi R., Calderoni M., Cassina E. M., Cioffi U., Guttadauro A., Libretti L., Pirondini E., Rimessi A., Tuoro A., Raveglia F., Passera, E, Orlandi, R, Calderoni, M, Cassina, E, Cioffi, U, Guttadauro, A, Libretti, L, Pirondini, E, Rimessi, A, Tuoro, A, and Raveglia, F

Subjects
tracheobronchial laceration, tracheal surgery, Surgery, endoscopy, iatrogenic tracheal injury, thoracic surgery
Abstract

Iatrogenic tracheobronchial injury (ITI) is an infrequent but potentially life-threatening disease, with significant morbidity and mortality rates. Its incidence is presumably underestimated since several cases are underrecognized and underreported. Causes of ITI include endotracheal intubation (EI) or percutaneous tracheostomy (PT). Most frequent clinical manifestations are subcutaneous emphysema, pneumomediastinum and unilateral or bilateral pneumothorax, even if occasionally ITI can occur without significant symptoms. Diagnosis mainly relies on clinical suspicion and CT scan, although flexible bronchoscopy remains the gold standard, allowing to identify location and size of the injury. EI and PT related ITIs more commonly consist of longitudinal tear involving the pars membranacea. Based on the depth of tracheal wall injury, Cardillo and colleagues proposed a morphologic classification of ITIs, attempting to standardize their management. Nevertheless, in literature there are no unambiguous guidelines on the best therapeutic modality: management and its timing remain controversial. Historically, surgical repair was considered the gold standard, mainly in high-grade lesions (IIIa-IIIb), carrying high morbi-mortality rates, but currently the development of promising endoscopic techniques through rigid bronchoscopy and stenting could allow for bridge treatment, delaying surgical approach after improving general conditions of the patient, or even for definitive repair, ensuring lower morbi-mortality rates especially in high-risk surgical candidates. Our perspective review will cover all the above issues, aiming at providing an updated and clear diagnostic-therapeutic pathway protocol, which could be applied in case of unexpected ITI.

Published
2023

26. Management of COVID-19 related tracheal stenosis: The state of art

Author

Orlandi R., Raveglia F., Calderoni M., Cassina E. M., Cioffi U., Guttadauro A., Libretti L., Pirondini E., Rimessi A., Tuoro A., Passera E., Orlandi, R, Raveglia, F, Calderoni, M, Cassina, E, Cioffi, U, Guttadauro, A, Libretti, L, Pirondini, E, Rimessi, A, Tuoro, A, and Passera, E

Subjects
tracheal procedure, tracheal stenosi, endoscopic thoracic surgery, COVID-19, Surgery, thoracic surgery
Abstract

Tracheal stenosis (TS) is a debilitating disease promoted by pathologic narrowing of the trachea. The acute respiratory distress syndrome caused by COVID-19 has been demonstrated to trigger enhanced inflammatory response and to require prolonged invasive mechanical ventilation as well as high frequency of re-intubation or emergency intubation, thus increasing the rate and complexity of TS. The standard-of-care of COVID-19-related tracheal complications has yet to be established and this is a matter of concern. This review aims at collecting latest evidence on this disease, providing an exhaustive overview on its distinctive features and open issues, and investigating different diagnostic and therapeutic strategies to handle COVID-19-induced TS, focusing on endoscopic versus open surgical approach. The former encompasses bronchoscopic procedures: electrocautery or laser-assisted incisions, ballooning dilation, submucosal steroid injection, endoluminal stenting. The latter consists of tracheal resection with end-to-end anastomosis. As a rule, traditionally, the endoscopic management is restricted to short, low-grade, and simple TS, whereas the open techniques are employed in long, high-grade, and complex TS. However, the critical conditions or extreme comorbidities of several COVID-19 patients, as well as the marked inflammation in tracheal mucosa, have led some authors to apply endoscopic management also in complex TS, recording acceptable results. Although severe COVID-19 seems to be an issue of the past, its long-term complications are still unknown and considering the increased rate and complexity of TS in these patients, we strongly believe that it is worth to focus on it, attempting to find the best management strategy for COVID-19-related TS.

Published
2023

27. First spectroscopic study of odd-odd Cu78

Author

Pedersen, L. G., primary, Sahin, E., additional, Görgen, A., additional, Bello Garrote, F. L., additional, Tsunoda, Y., additional, Otsuka, T., additional, Niikura, M., additional, Nishimura, S., additional, Xu, Z., additional, Baba, H., additional, Benzoni, G., additional, Browne, F., additional, Bruce, A. M., additional, Ceruti, S., additional, Crespi, F. C. L., additional, Daido, R., additional, de Angelis, G., additional, Delattre, M.-C., additional, Dombradi, Zs., additional, Doornenbal, P., additional, Fang, Y., additional, Franchoo, S., additional, Gey, G., additional, Gottardo, A., additional, Isobe, T., additional, John, P. R., additional, Jung, H. S., additional, Kojouharov, I., additional, Kubo, T., additional, Kurz, N., additional, Kuti, I., additional, Li, Z., additional, Lorusso, G., additional, Matea, I., additional, Matsui, K., additional, Mengoni, D., additional, Miyazaki, T., additional, Modamio, V., additional, Momiyama, S., additional, Morales, A. I., additional, Morfouace, P., additional, Napoli, D. R., additional, Naqvi, F., additional, Nishibata, H., additional, Odahara, A., additional, Orlandi, R., additional, Patel, Z., additional, Rice, S., additional, Sakurai, H., additional, Schaffner, H., additional, Sinclair, L., additional, Söderström, P.-A., additional, Sohler, D., additional, Stefan, I. G., additional, Sumikama, T., additional, Suzuki, D., additional, Taniuchi, R., additional, Taprogge, J., additional, Vajta, Z., additional, Valiente-Dobón, J. J., additional, Watanabe, H., additional, Werner, V., additional, Wu, J., additional, Yagi, A., additional, Yalcinkaya, M., additional, Yokoyama, R., additional, and Yoshinaga, K., additional

Published
2023
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28. Axial and triaxial degrees of freedom in 72Zn

Author

Hellgartner, S., primary, Mücher, D., additional, Wimmer, K., additional, Bildstein, V., additional, Egido, J.L., additional, Gernhäuser, R., additional, Krücken, R., additional, Nowak, A.K., additional, Zielińska, M., additional, Bauer, C., additional, Benito, M.L.L., additional, Bottoni, S., additional, De Witte, H., additional, Elseviers, J., additional, Fedorov, D., additional, Flavigny, F., additional, Illana, A., additional, Klintefjord, M., additional, Kröll, T., additional, Lutter, R., additional, Marsh, B., additional, Orlandi, R., additional, Pakarinen, J., additional, Raabe, R., additional, Rapisarda, E., additional, Reichert, S., additional, Reiter, P., additional, Scheck, M., additional, Seidlitz, M., additional, Siebeck, B., additional, Siesling, E., additional, Steinbach, T., additional, Stora, T., additional, Vermeulen, M., additional, Voulot, D., additional, Warr, N., additional, and Wenander, F.J.C., additional

Published
2023
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29. Axial and triaxial degrees of freedom in Zn

Author

Hellgartner, S., Mücher, D., Wimmer, K., Bildstein, V., Egido, J.L., Gernhäuser, R., Krücken, R., Nowak, A.K., Zielińska, M., Bauer, C., Benito, M.L.L., Bottoni, S., De Witte, H., Elseviers, J., Fedorov, D., Flavigny, F., Illana, A., Klintefjord, M., Kröll, T., Lutter, R., Marsh, B., Orlandi, R., Pakarinen, J., Raabe, R., Rapisarda, E., Reichert, S., Reiter, P., Scheck, M., Seidlitz, M., Siebeck, B., Siesling, E., Steinbach, T., Stora, T., Vermeulen, M., Voulot, D., Warr, N., and Wenander, F.J.C.

Abstract

The unstable N=42 nucleus $^{72}$Zn has been studied using multiple safe Coulomb excitation in inverse kinematics. The experiment was performed at the REX-ISOLDE facility at CERN making first use of the silicon detector array C-REX in combination with the γ-ray spectrometer Miniball. The high angular coverage of C-REX allowed to determine the reduced transition strengths for the decay of the yrast 01+, 21+ and 41+ as well as of the 02+ and 22+ states in $^{72}$Zn. The quadrupole moments of the 21+, 41+ and 22+ states were extracted. Using model independent quadrupole invariants, the ground state of $^{72}$Zn was found to have an average deformation in the γ degree of freedom close to maximum triaxiality. In comparison to experimental data in zinc isotopes with N<40, the collectivity of the 41+ state in neutron-rich $^{72}$Zn is significantly larger, indicating a collective yrast band based on the ground state of $^{72}$Zn. In contrast, a low experimental B(E2;02+→21+) strength was determined, indicating a different structure for the 02+ state. Shell-model calculations propose a 02+ state featuring a larger fraction of the (spherical) N=40 closed-shell configuration in its wave function than for the 01+ ground state.The results were also compared with beyond mean field calculations which corroborate the large deformation in the γ degree of freedom, while pointing to a more deformed 02+ state. These experimental and theoretical findings establish the importance of the γ degree of freedom in the ground state of $^{72}$Zn, located between the $^{68,70}$Ni nuclei that have spherical ground states, and $^{76}$Ge, which has a rigid triaxial shape.

Published
2023

30. Experimental Level Scheme of \(^{78}\)Cu

Author

Pedersen, L.G., primary, Sahin, E., additional, Görgen, A., additional, Bello Garrote, F.L., additional, Tsunoda, Y., additional, Otsuka, T., additional, Niikura, M., additional, Nishimura, S., additional, Xu, Z., additional, Baba, H., additional, Benzoni, G., additional, Browne, F., additional, Bruce, A.M., additional, Ceruti, S., additional, Crespi, F.C.L., additional, Daido, R., additional, de Angelis, G., additional, Delattre, M.-C., additional, Dombradi, Zs., additional, Doornenbal, P., additional, Fang, Y., additional, Franchoo, S., additional, Gey, G., additional, Gottardo, A., additional, Isobe, T., additional, John, P.R., additional, Jung, H.S., additional, Kojouharov, I., additional, Kubo, T., additional, Kurz, N., additional, Kuti, I., additional, Li, Z., additional, Lorusso, G., additional, Matea, I., additional, Matsui, K., additional, Mengoni, D., additional, Miyazaki, T., additional, Modamio, V., additional, Momiyama, S., additional, Morales, A.I., additional, Morfouace, P., additional, Napoli, D.R., additional, Naqvi, F., additional, Nishibata, H., additional, Odahara, A., additional, Orlandi, R., additional, Patel, Z., additional, Rice, S., additional, Sakurai, H., additional, Schaffner, H., additional, Sinclair, L., additional, Söderström, P.-A., additional, Sohler, D., additional, Stefan, I.G., additional, Sumikama, T., additional, Suzuki, D., additional, Taniuchi, R., additional, Taprogge, J., additional, Vajta, Z., additional, Valiente-Dobón, J.J., additional, Watanabe, H., additional, Werner, V., additional, Wu, J., additional, Yagi, A., additional, Yalcinkaya, M., additional, Yokoyama, R., additional, and Yoshinaga, K., additional

Published
2023
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31. Early outcomes of 'low-risk' patients undergoing lung resection assessed by cardiopulmonary exercise testing: Single-institution experience

Author

Orlandi, R., Rinaldo, R.F., Mazzucco, A., Baccelli, A., Mondoni, M., Marchetti, F., Zagaria, M., Cefalo, J., Leporati, A., Montoli, M., Ghilardi, G., Baisi, A., and Centanni, S.

Subjects
Settore MED/18 - Chirurgia Generale, VO2peak, postoperative outcomes, cardiopulmonary complications, Settore MED/10 - Malattie dell'Apparato Respiratorio, Settore MED/21 - Chirurgia Toracica, cardiopulmonary exercise testing (CPET), peak oxygen uptake, thoracic surgery, Surgery
Abstract

ObjectiveCardiopulmonary exercise testing (CPET) is currently recommended for all patients undergoing lung resection with either respiratory comorbidities or functional limitations. The main parameter evaluated is oxygen consumption at peak (VO2peak). Patients with VO2peak above 20 ml/kg/min are classified as low risk surgical candidates. The aims of this study were to evaluate postoperative outcomes of low-risk patients, and to compare their outcomes with those of patients without pulmonary impairment at respiratory function testing.MethodsRetrospective monocentric observational study was designed, evaluating outcomes of patients undergoing lung resection at San Paolo University Hospital, Milan, Italy, between January 2016 and November 2021, preoperatively assessed by CPET, according to 2009 ERS/ESTS guidelines. All low-risk patients undergoing any extent surgical lung resection for pulmonary nodules were enrolled. Postoperative major cardiopulmonary complications or death, occurring within 30 days from surgery, were assessed. A case-control study was nested, matching 1:1 for type of surgery the cohort population with control patients without functional respiratory impairment consecutively undergoing surgery at the same centre in the study period.ResultsA total of 80 patients were enrolled: 40 subjects were preoperatively assessed by CPET and deemed at low risk, whereas 40 subjects represented the control group. Among the first, 4 patients (10%) developed major cardiopulmonary complications, and 1 patient (2.5%) died within 30 days from surgery. In the control group, 2 patients (5%) developed complications and none of the patients (0%) died. The differences in morbidity and mortality rates did not reach statistically significance. Instead, age, weight, BMI, smoking history, COPD incidence, surgical approach, FEV1, Tiffenau, DLCO and length of hospital stay resulted significantly different between the two groups. At a case-by-case analysis, CPET revealed a pathological pattern in each complicated patient, in spite of VO2peak above target for safe surgery.ConclusionsPostoperative outcomes of low-risk patients undergoing lung resections are comparable to those of patients without any pulmonary functional impairment; nonetheless the formers represent a dramatically different category of individuals from the latter and may harbour few patients with worse outcomes. CPET variables overall interpretation may add to the VO2peak in identifying higher risk patients, even in this subgroup.

Published
2023

32. Signs and symptoms of COVID-19 in patients with multiple sclerosis

Author

Schiavetti I., Carmisciano L., Ponzano M., Cordioli C., Cocco E., Marfia G. A., Inglese M., Filippi M., Radaelli M., Bergamaschi R., Immovilli P., Capobianco M., De Rossi N., Brichetto G., Scandellari C., Cavalla P., Pesci I., Confalonieri P., Perini P., Trojano M., Lanzillo R., Tedeschi G., Comi G., Battaglia M. A., Patti F., Salvetti M., Sormani M. P., Abbadessa G., Aguglia U., Allegorico L., Rossi Allegri B. M., Alteno A., Amato M. P., Annovazzi P., Antozzi C., Appendino L., Arena S., Baione V., Balgera R., Barcella V., Baroncini D., Barrila C., Bellacosa A., Bellucci G., Bergamaschi V., Bezzini D., Biolzi B., Bisecco A., Bonavita S., Borriello G., Bosa C., Bosco A., Bovis F., Bozzali M., Brambilla L., Brescia Morra V., Buccafusca M., Bucciantini E., Bucello S., Buscarinu M. C., Cabboi M. P., Calabrese M., Calabria F., Caleri F., Camilli F., Caniatti L. M., Cantello R., Capra R., Capuano R., Carta P., Celani M. G., Cellerino M., Cerqua R., Chisari C., Clerici R., Clerico M., Cola G., Conte A., Conti M. Z., Cordano C., Cordera S., Corea F., Correale C., Cottone S., Crescenzo F., Curti E., d'Ambrosio A., D'Amico E., Danni M. C., d'Arma A., Dattola V., de Biase S., De Luca G., De Mercanti S. F., De Mitri P., De Stefano N., Della Cava F. M., Cava M. D., Di Lemme S., di Napoli M., Di Sapio A., Docimo R., Dutto A., Evangelista L., Fanara S., Fantozzi R., Ferraro D., Ferro M. T., Fioretti C., Fratta M., Frau J., Fronza M., Furlan R., Gajofatto A., Gallo A., Gallo P., Gasperini C., Ghazaryan A., Giometto B., Gobbin F., Govone F., Granella F., Grange E., Grasso M. G., Grimaldi L. M. E., Guareschi A., Guaschino C., Guerrieri S., Guidetti D., Juergenson I. B., Iaffaldano P., Ianniello A., Iasevoli L., Imperiale D., Infante M. T., Iodice R., Iovino A., Konrad G., Landi D., Lapucci C., Lavorgna L., L'Episcopo M. R., Leva S., Liberatore G., Lo Re M., Longoni M., Lopiano L., Lorefice L., Lucchini M., Lus G., Maimone D., Malentacchi M., Mallucci G., Malucchi S., Mancinelli C. R., Mancinelli L., Manganotti P., Maniscalco G. T., Mantero V., Marangoni S., Marastoni D., Marinelli F., Marti A., Boneschi Martinelli F., Masserano Z. F., Matta F., Mendozzi L., Meucci G., Miante S., Miele G., Milano E., Mirabella M., Missione R., Moccia M., Moiola L., Montepietra S., MontiBragadin M., Montini F., Motta R., Nardone R., Gabri Nicoletti C., Nobile-Orazio E., Nozzolillo A., Onofrj M., Orlandi R., Palmieri A., Paolicelli D., Pasquali L., Pasto L., Pedrazzoli E., Petracca M., Petrone A., Piantadosi C., Pietroboni A. M., Pinardi F., Portaccio E., Pozzato M., Pozzilli C., Prosperini L., Protti A., Ragonese P., Rasia S., Realmuto S., Repice A., Rigoni E., Rilla M. T., Rinaldi F., Romano C. M., Ronzoni M., Rovaris M., Ruscica F., Sabattini L., Salemi G., Saraceno L., Sartori A., Sbragia E., Scarano G. I., Scarano V., Sessa M., Sgarito C., Sibilia G., Siciliano G., Signori A., Signoriello E., Sinisi L., Sireci F., Sola P., Solaro C., Sotgiu S., Sparaco M., Stromillo M. L., Strumia S., Susani E. L., Tabiadon G., Teatini F., Tomassini V., Tonietti S., Torri V., Tortorella C., Toscano S., Totaro R., Trotta M., Turano G., Ulivelli M., Valentino M., Vaula G., Vecchio D., Vercellino M., Verrengia E. P., Vianello M., Virgilio E., Vitetta F., Vollaro S., Zaffaroni M., Zampolini M., Zarbo I. R., Zito A., Zuliani L., Schiavetti, Irene, Carmisciano, Luca, Ponzano, Marta, Cordioli, Cinzia, Cocco, Eleonora, Marfia, Girolama Alessandra, Inglese, Matilde, Filippi, Massimo, Radaelli, Marta, Bergamaschi, Roberto, Immovilli, Paolo, Capobianco, Marco, De Rossi, Nicola, Brichetto, Giampaolo, Scandellari, Cinzia, Cavalla, Paola, Pesci, Ilaria, Confalonieri, Paolo, Perini, Paola, Trojano, Maria, Lanzillo, Roberta, Tedeschi, Gioacchino, Comi, Giancarlo, Battaglia, Mario Alberto, Patti, Francesco, Salvetti, Marco, Sormani, Maria Pia, Gianmarco, Abbadessa, Umberto, Aguglia, Allegorico, Lia, Beatrice Maria Rossi Allegri, Anastasia, Alteno, Amato, MARIA PIA, Pietro, Annovazzi, Carlo, Antozzi, Lucia, Appendino, Sebastiano, Arena, Viola, Baione, Roberto, Balgera, Valeria, Barcella, Damiano, Baroncini, Caterina, Barrilà, Alessandra, Bellacosa, Gianmarco, Bellucci, Valeria, Bergamaschi, Daiana, Bezzini, Beatrice, Biolzi, Bisecco, Alvino, Simona, Bonavita, Giovanna, Borriello, Chiara, Bosa, Antonio, Bosco, Francesca, Bovi, Marco, Bozzali, Laura, Brambilla, BRESCIA MORRA, Vincenzo, Maria, Buccafusca, Elisabetta, Bucciantini, Sebastiano, Bucello, Maria Chiara Buscarinu, Maria Paola Cabboi, Massimiliano, Calabrese, Francesca, Calabria, Francesca, Caleri, Federico, Camilli, Luisa Maria Caniatti, Roberto, Cantello, Ruggero, Capra, Rocco, Capuano, Patrizia, Carta, Maria Grazia Celani, Maria, Cellerino, Raffaella, Cerqua, Clara, Chisari, Raffaella, Clerici, Marinella, Clerico, Gaia, Cola, Antonella, Conte, Marta Zaffira Conti, Christian, Cordano, Susanna, Cordera, Francesco, Corea, Claudio, Correale, Salvatore, Cottone, Francesco, Crescenzo, Erica, Curti, Alessandro, D’Ambrosio, Emanuele, D’Amico, Maura Chiara Danni, Alessia, D’Arma, Vincenzo, Dattola, Stefano de Biase, Giovanna De Luca, Stefania Federica De Mercanti, Paolo De Mitri, Nicola De Stefano, Fabio Maria Della Cava, Marco Della Cava, Sonia Di Lemme, Mario di Napoli, Alessia Di Sapio, Renato, Docimo, Anna, Dutto, Luana, Evangelista, Salvatore, Fanara, Roberta, Fantozzi, Diana, Ferraro, Maria Teresa Ferrò, Cristina, Fioretti, Mario, Fratta, Jessica, Frau, Marzia, Fronza, Roberto, Furlan, Alberto, Gajofatto, Gallo, Antonio, Paolo, Gallo, Claudio, Gasperini, Anna, Ghazaryan, Bruno, Giometto, Francesca, Gobbin, Flora, Govone, Franco, Granella, Erica, Grange, Grasso, MARIA GRAZIA, Grimaldi, Luigi M. E., Angelica, Guareschi, Clara, Guaschino, Simone, Guerrieri, Donata, Guidetti, Ina Barbara Juergenson, Pietro, Iaffaldano, Ianniello, Antonio, Luigi, Iasevoli, Daniele, Imperiale, Maria Teresa Infante, Iodice, Rosa, Iovino, Aniello, Giovanna, Konrad, Doriana, Landi, Caterina, Lapucci, Luigi, Lavorgna, Maria Rita L’Episcopo, Serena, Leva, Giuseppe, Liberatore, Marianna Lo Re, Marco, Longoni, Leonardo, Lopiano, Lorena, Lorefice, Matteo, Lucchini, Lus, Giacomo, Maimone, Davide, Maria, Malentacchi, Giulia, Mallucci, Simona, Malucchi, Chiara Rosa Mancinelli, Luca, Mancinelli, Paolo, Manganotti, Giorgia Teresa Maniscalco, Vittorio, Mantero, Sabrina, Marangoni, Damiano, Marastoni, Fabiana, Marinelli, Marti, NICOLA ALESSANDRO, Filippo Boneschi Martinelli, Zoli Federco Masserano, Francesca, Matta, Laura, Mendozzi, Giuseppe, Meucci, Silvia, Miante, Giuseppina, Miele, Eva, Milano, Massimiliano, Mirabella, Rosanna, Missione, Moccia, Marcello, Lucia, Moiola, Sara, Montepietra, Margherita, Montibragadin, Federico, Montini, Roberta, Motta, Raffaele, Nardone, Carolina Gabri Nicoletti, Eduardo, Nobile‐orazio, Nozzolillo, Agostino, Marco, Onofrj, Riccardo, Orlandi, Anna, Palmieri, Damiano, Paolicelli, Livia, Pasquali, Luisa, Pastò, Elisabetta, Pedrazzoli, Petracca, Maria, Alfredo, Petrone, Carlo, Piantadosi, Pietroboni, Anna M., Federica, Pinardi, Emilio, Portaccio, Mattia, Pozzato, Pozzilli, Carlo, Luca, Prosperini, Alessandra, Protti, Paolo, Ragonese, Sarah, Rasia, Sabrina, Realmuto, Anna, Repice, Eleonora, Rigoni, Maria Teresa Rilla, DELLA RATTA RINALDI, Francesca, Calogero Marcello Romano, Marco, Ronzoni, Marco, Rovari, Francesca, Ruscica, Loredana, Sabattini, Giuseppe, Salemi, Lorenzo, Saraceno, Alessia, Sartori, Arianna, Sartori, Elvira, Sbragia, Giuditta Ilaria Scarano, Valentina, Scarano, Maria, Sessa, Caterina, Sgarito, Sibilia, Grazia, Gabriele, Siciliano, Alessio, Signori, Signoriello, Elisabetta, Sinisi, Leonardo, Francesca, Sireci, Patrizia, Sola, Claudio, Solaro, Stefano, Sotgiu, Maddalena, Sparaco, Maria Laura Stromillo, Silvia, Strumia, Emanuela Laura Susani, Giulietta, Tabiadon, Francesco, Teatini, Valentina, Tomassini, Simone, Tonietti, Valentina, Torri, Tortorella, Carla, Simona, Toscano, Rocco, Totaro, Maria, Trotta, Gabriella, Turano, Monica, Ulivelli, Manzo, Valentino, Giovanna, Vaula, Domizia, Vecchio, Marco, Vercellino, Elena Pinuccia Verrengia, Marika, Vianello, Eleonora, Virgilio, Francesca, Vitetta, Vollaro, Stefano, Mauro, Zaffaroni, Mauro, Zampolini, Ignazio Roberto Zarbo, Antonio, Zito, and Luigi Zuliani, Schiavetti, I., Carmisciano, L., Ponzano, M., Cordioli, C., Cocco, E., Marfia, G. A., Inglese, M., Filippi, M., Radaelli, M., Bergamaschi, R., Immovilli, P., Capobianco, M., De Rossi, N., Brichetto, G., Scandellari, C., Cavalla, P., Pesci, I., Confalonieri, P., Perini, P., Trojano, M., Lanzillo, R., Tedeschi, G., Comi, G., Battaglia, M. A., Patti, F., Salvetti, M., Sormani, M. P., Abbadessa, G., Aguglia, U., Allegorico, L., Rossi Allegri, B. M., Alteno, A., Amato, M. P., Annovazzi, P., Antozzi, C., Appendino, L., Arena, S., Baione, V., Balgera, R., Barcella, V., Baroncini, D., Barrila, C., Bellacosa, A., Bellucci, G., Bergamaschi, V., Bezzini, D., Biolzi, B., Bisecco, A., Bonavita, S., Borriello, G., Bosa, C., Bosco, A., Bovis, F., Bozzali, M., Brambilla, L., Brescia Morra, V., Buccafusca, M., Bucciantini, E., Bucello, S., Buscarinu, M. C., Cabboi, M. P., Calabrese, M., Calabria, F., Caleri, F., Camilli, F., Caniatti, L. M., Cantello, R., Capra, R., Capuano, R., Carta, P., Celani, M. G., Cellerino, M., Cerqua, R., Chisari, C., Clerici, R., Clerico, M., Cola, G., Conte, A., Conti, M. Z., Cordano, C., Cordera, S., Corea, F., Correale, C., Cottone, S., Crescenzo, F., Curti, E., D'Ambrosio, A., D'Amico, E., Danni, M. C., D'Arma, A., Dattola, V., de Biase, S., De Luca, G., De Mercanti, S. F., De Mitri, P., De Stefano, N., Della Cava, F. M., Cava, M. D., Di Lemme, S., di Napoli, M., Di Sapio, A., Docimo, R., Dutto, A., Evangelista, L., Fanara, S., Fantozzi, R., Ferraro, D., Ferro, M. T., Fioretti, C., Fratta, M., Frau, J., Fronza, M., Furlan, R., Gajofatto, A., Gallo, A., Gallo, P., Gasperini, C., Ghazaryan, A., Giometto, B., Gobbin, F., Govone, F., Granella, F., Grange, E., Grasso, M. G., Grimaldi, L. M. E., Guareschi, A., Guaschino, C., Guerrieri, S., Guidetti, D., Juergenson, I. B., Iaffaldano, P., Ianniello, A., Iasevoli, L., Imperiale, D., Infante, M. T., Iodice, R., Iovino, A., Konrad, G., Landi, D., Lapucci, C., Lavorgna, L., L'Episcopo, M. R., Leva, S., Liberatore, G., Lo Re, M., Longoni, M., Lopiano, L., Lorefice, L., Lucchini, M., Lus, G., Maimone, D., Malentacchi, M., Mallucci, G., Malucchi, S., Mancinelli, C. R., Mancinelli, L., Manganotti, P., Maniscalco, G. T., Mantero, V., Marangoni, S., Marastoni, D., Marinelli, F., Marti, A., Boneschi Martinelli, F., Masserano, Z. F., Matta, F., Mendozzi, L., Meucci, G., Miante, S., Miele, G., Milano, E., Mirabella, M., Missione, R., Moccia, M., Moiola, L., Montepietra, S., Montibragadin, M., Montini, F., Motta, R., Nardone, R., Gabri Nicoletti, C., Nobile-Orazio, E., Nozzolillo, A., Onofrj, M., Orlandi, R., Palmieri, A., Paolicelli, D., Pasquali, L., Pasto, L., Pedrazzoli, E., Petracca, M., Petrone, A., Piantadosi, C., Pietroboni, A. M., Pinardi, F., Portaccio, E., Pozzato, M., Pozzilli, C., Prosperini, L., Protti, A., Ragonese, P., Rasia, S., Realmuto, S., Repice, A., Rigoni, E., Rilla, M. T., Rinaldi, F., Romano, C. M., Ronzoni, M., Rovaris, M., Ruscica, F., Sabattini, L., Salemi, G., Saraceno, L., Sartori, A., Sbragia, E., Scarano, G. I., Scarano, V., Sessa, M., Sgarito, C., Sibilia, G., Siciliano, G., Signori, A., Signoriello, E., Sinisi, L., Sireci, F., Sola, P., Solaro, C., Sotgiu, S., Sparaco, M., Stromillo, M. L., Strumia, S., Susani, E. L., Tabiadon, G., Teatini, F., Tomassini, V., Tonietti, S., Torri, V., Tortorella, C., Toscano, S., Totaro, R., Trotta, M., Turano, G., Ulivelli, M., Valentino, M., Vaula, G., Vecchio, D., Vercellino, M., Verrengia, E. P., Vianello, M., Virgilio, E., Vitetta, F., Vollaro, S., Zaffaroni, M., Zampolini, M., Zarbo, I. R., Zito, A., and Zuliani, L.

Subjects
Multiple Sclerosis, Anosmia, Clinical Sciences, neurological disorders, Neurodegenerative, Settore MED/26, demyelinating disease, COVID-19, demyelinating diseases, disease-modifying treatment, multiple sclerosis, Humans, neurological disorder, Aged, Neurology & Neurosurgery, SARS-CoV-2, Pain Research, Neurosciences, Brain Disorders, Settore MED/26 - NEUROLOGIA, Good Health and Well Being, Neurology, multiple sclerosi, Neurology (clinical), MuSC-19 Study Group, Ageusia, Human
Abstract

Background and purpose: Clinical outcomes of multiple sclerosis (MS) patients affected by coronavirus disease 2019 (COVID-19) have been thoroughly investigated, but a further analysis on main signs and symptoms and their risk factors still needs attention. The objective of this study was to group together and describe based on similarity the most common signs and symptoms of COVID-19 in MS patients and identify all factors associated with their manifestation. Method: Logistic and linear regression models were run to recognize factors associated with each pooled group of symptoms and their total number. Results: From March 2020 to November 2021, data were collected from 1354 MS patients with confirmed infection of COVID-19. Ageusia and anosmia was less frequent in older people (odds ratio [OR] 0.98; p=0.005) and more in smoker patients (OR 1.39; p=0.049). Smoke was also associated with an incremental number of symptoms (OR 1.24; p=0.031), substance abuse (drugs or alcohol), conjunctivitis and rash (OR 5.20; p=0.042) and the presence of at least one comorbidity with shortness of breath, tachycardia or chest pain (OR 1.24; p=0.008). Some disease-modifying therapies were associated with greater frequencies of certain COVID-19 symptoms (association between anti-CD20 therapies and increment in the number of concomitant symptoms: OR 1.29; p=0.05). Differences in frequencies between the three waves were found for flu-like symptoms (G1, p=0.024), joint or muscle pain (G2, p=0.013) and ageusia and anosmia (G5, p < 0.001). All cases should be referred to variants up to Delta. Conclusion: Several factors along with the choice of specific therapeutic approaches might have a different impact on the occurrence of some COVID-19 symptoms.

Published
2022

33. Study of medium-spin states of neutron-rich 87, 89, 91Rb isotopes

Author

Torres, D. A., Chapman, R., Kumar, V., Hadinia, B., Hodsdon, A., Labiche, M., Liang, X., O’Donnell, D., Ollier, J., Orlandi, R., Smith, J. F., Spohr, K. -M., Wady, P., Wang, Z. M., Corradi, L., Fioretto, E., Gadea, A., de Angelis, G., Mărginean, N., Napoli, D. R., Sahin, E., Stefanini, A. M., Valiente-Dobón, J. J., Vedova, F. D., Axiotis, M., Martinez, T., Szilner, S., Bazzacco, D., Beghini, S., Farnea, E., Mărginean, R., Mengoni, D., Montagnoli, G., Recchia, F., Scarlassara, F., Ur, C. A., Lenzi, S. M., Lunardi, S., Kröll, T., Haas, F., Faul, T., Hjorth-Jensen, M., Carlsson, B. G., Freeman, S. J., Smith, A. G., Jones, G., Thompson, N., Pollarolo, G., and Simpson, G. S.

Published
2019
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34. Electromagnetic properties of low-lying states in neutron-deficient Hg isotopes: Coulomb excitation of 182Hg, 184Hg, 186Hg and 188Hg

Author

Wrzosek-Lipska, K., Rezynkina, K., Bree, N., Zielińska, M., Gaffney, L. P., Petts, A., Andreyev, A., Bastin, B., Bender, M., Blazhev, A., Bruyneel, B., Butler, P. A., Carpenter, M. P., Cederkäll, J., Clément, E., Cocolios, T. E., Deacon, A. N., Diriken, J., Ekström, A., Fitzpatrick, C., Fraile, L. M., Fransen, Ch., Freeman, S. J., García-Ramos, J. E., Geibel, K., Gernhäuser, R., Grahn, T., Guttormsen, M., Hadinia, B., Hadyńska-Klȩk, K., Hass, M., Heenen, P. -H., Herzberg, R. -D., Hess, H., Heyde, K., Huyse, M., Ivanov, O., Jenkins, D. G., Julin, R., Kesteloot, N., Kröll, Th., Krücken, R., Larsen, A. C., Lutter, R., Marley, P., Napiorkowski, P. J., Orlandi, R., Page, R. D., Pakarinen, J., Patronis, N., Peura, P. J., Piselli, E., Próchniak, L., Rahkila, P., Rapisarda, E., Reiter, P., Robinson, A. P., Scheck, M., Siem, S., Singh Chakkal, K., Smith, J. F., Srebrny, J., Stefanescu, I., Tveten, G. M., Van Duppen, P., Van de Walle, J., Voulot, D., Warr, N., Wiens, A., and Wood, J. L.

Published
2019
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36. New K isomers in Cf248

Author

Orlandi, R., primary, Makii, H., additional, Nishio, K., additional, Hirose, K., additional, Asai, M., additional, Tsukada, K., additional, Sato, T. K., additional, Ito, Y., additional, Suzaki, F., additional, Nagame, Y., additional, Andreyev, A. N., additional, Ideguchi, E., additional, Aoi, N., additional, Pham, T. T., additional, Yan, S. Q., additional, Shen, Y. P., additional, Gao, B., additional, and Li, G., additional

Published
2022
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37. The EUFOREA pocket guide for chronic rhinosinusitis

Author

Hellings, P.W., primary, Fokkens, W.J., additional, Orlandi, R., additional, Adriaensen, G.F., additional, Alobid, I., additional, Baroody, F.M., additional, Bjermer, L., additional, Senior, B.A., additional, Cervin, A., additional, Cohen, N.A., additional, Constantinidis, J., additional, De Corso, E., additional, Desrosiers, M., additional, Diamant, Z., additional, Douglas, R.G., additional, Gane, S., additional, Gevaert, P., additional, Han, J.K., additional, Harvey, R.J., additional, Hopkins, C., additional, Kern, R.C., additional, Landis, B.N., additional, Lee, J.T., additional, Lee, S.E., additional, Leunig, A., additional, Lund, V.J., additional, Manuel-Sprekelsen, B., additional, Mullol, J., additional, Philpott, C., additional, Prokopakis, E., additional, Reitsma, S., additional, Ryan, D., additional, Salmi, S., additional, Scadding, G., additional, Schlosser, R.J., additional, Steinsvik, A., additional, Tomazic, P.V., additional, Van Staeyen, E., additional, Van Zele, T., additional, Vanderveken, O., additional, Viskens, A-S., additional, Conti, D., additional, and Wagenmann, M., additional

Published
2022
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38. Isolation of extracellular vesicles from bitch's amnion-derived cells culture and their CD59 expression: Preliminary results

Author

Pastore, S, Troisi, A, Romani, R, Bellezza, I, Gargaro, M, De Michele, A, Orlandi, R, Guerrera, G, Bazzano, M, and Polisca, A

Subjects
Immunomodulation, Complement system, Food Animals, Amnion derived mesenchymal stem cells, Equine, Pregnancy, Reproduction, Bitch, Animal Science and Zoology, Extracellular vesicles (EVs), Small Animals, CD59
Abstract

Extracellular vesicles (EVs) are small spherical particles surrounded by a membrane with an unusual lipid composition and a striking cholesterol/phospholipidic ratio. About 2000 lipid and 3500 protein species were identified in EVs secreted by different cell sources. EVs mediate cell to cell communication in proximity to or distant from the cell of origin. In particular, it was suggested that they represent modulators of multiple processes during pregnancy. The aim of this study was to identify the presence of EVs in canine amnion-derived cells (ASCs) culture and the expression of CD 59 on their surface. Amniotic membrane was collected in PBS with antibiotics added from 2 bitches during elective caesarean section. Cells culture was prepared and EVs were isolated. EVs were used to evaluate CD59 expression by flow cytofluorimetry. We found that the majority of EVs expressed CD59. Our results could increase the knowledge about the complex mechanisms that regulate the pregnancy in the bitch.

Published
2022

39. Proton-hole and core-excited states in the semi-magic nucleus 131In82

Author

Taprogge, J., Jungclaus, A., Grawe, H., Borzov, I. N., Nishimura, S., Doornenbal, P., Lorusso, G., Simpson, G. S., Söderström, P. -A., Sumikama, T., Xu, Z. Y., Baba, H., Browne, F., Fukuda, N., Gernhäuser, R., Gey, G., Inabe, N., Isobe, T., Jung, H. S., Kameda, D., Kim, G. D., Kim, Y. -K., Kojouharov, I., Kubo, T., Kurz, N., Kwon, Y. K., Li, Z., Sakurai, H., Schaffner, H., Shimizu, Y., Steiger, K., Suzuki, H., Takeda, H., Vajta, Zs., Watanabe, H., Wu, J., Yagi, A., Yoshinaga, K., Benzoni, G., Bönig, S., Chae, K. Y., Coraggio, L., Daugas, J. -M., Drouet, F., Gadea, A., Gargano, A., Ilieva, S., Itaco, N., Kondev, F. G., Kröll, T., Lane, G. J., Montaner-Pizá, A., Moschner, K., Mücher, D., Naqvi, F., Niikura, M., Nishibata, H., Odahara, A., Orlandi, R., Patel, Z., Podolyák, Zs., and Wendt, A.

Published
2016
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44. Chemokine CCL19 and Its Receptors CCR7 and CCRL1 in Chronic Rhinosinusitis

Author

Mahomva CR, Smith KA, Minkah PAB, Witt BL, Oakley GM, Orlandi RR, Alt JA, and Pulsipher A

Subjects
chronic rhinosinusitis with nasal polyps, chemokines, cytokines, gene expression, protein expression, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950
Abstract

Chengetai R Mahomva,1,&ast; Kristine A Smith,1,&ast; Prince AB Minkah,2 Benjamin L Witt,3 Gretchen M Oakley,1 Richard R Orlandi,1 Jeremiah A Alt,1,2,4 Abigail Pulsipher1,2,4 1Department of Otolaryngology-Head and Neck Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA; 2Department of Molecular Pharmaceutics, University of Utah College of Pharmacy, Salt Lake City, UT, USA; 3Cytopathology Section, University of Utah School of Medicine, Salt Lake City, UT, USA; 4Utah Center for Nanomedicine, University of Utah College of Pharmacy, Salt Lake City, UT, USA&ast;These authors contributed equally to this workCorrespondence: Abigail Pulsipher, University of Utah School of Medicine, Department of Otolaryngology-Head and Neck Surgery, 36 South Wasatch Drive, Salt Lake City, UT, 84112, USA, Tel +1 4342493268, Fax +1 8015855744, Email abigail.pulsipher@utah.eduBackground: CCL19 has been shown to predict disease severity in COVID-19 and treatment response in rheumatoid arthritis. CCL19 can exert both pro- and anti-inflammatory effects and is elevated in chronic rhinosinusitis (CRS). However, its role in CRS remains unknown. This study sought to determine the transcriptional changes in CCL19, its receptors, and associated cytokines and their association with disease severity in CRS.Methods: A clinical database of control subjects and patients with CRS was examined. Lund-Kennedy, Lund-Mackay, Sinonasal Outcomes Test 22 (SNOT-22), and rhinosinusitis disability index (RSDI) scores were collected at enrollment. mRNA was extracted from sinonasal tissues and subjected to multiplex gene expression analysis. Gene transcript differences between patients with CRS and controls were compared and correlated with disease severity metrics. Immunohistochemical analyses of CCL19, CCR7, and CCRL1 were conducted to compare differences in protein expression between cohorts. A subgroup analysis was performed to compare transcriptional and protein expression difference between patients with (CRSwNP) and without (CRSsNP) nasal polyps and controls.Results: Thirty-eight subjects (control group, n=7; CRS group, n=31) were included in this study. CCRL1 (p=0.0093) and CCR7 (p=0.017) levels were significantly elevated in CRS compared to those in controls. CCL19 (p=0.038) and CCR7 (p=0.0097) levels were elevated in CRSwNP and CCRL1 was elevated in CRSsNP (p=0.0004). CCR7 expression was significantly elevated in sinonasal epithelial cells in CRSwNP (p=0.04). CCL19 expression was positively correlated with TNFA expression (p< 0.0002). CCL19 and CCR7 expression was positively correlated with SNOT-22 and RSDI scores (p< 0.05).Conclusion: CCL19 and CCR7 may modulate TNF-α-driven pro-inflammatory signaling and contribute to increased disease severity in CRS. Mechanistic studies are required to further elucidate the role of CCRL1 in CRS.Keywords: chronic rhinosinusitis with nasal polyps, chemokines, cytokines, gene expression, protein expression

Published
2024

46. $\ensuremath{\gamma}$-ray spectroscopy of low-lying yrast and non-yrast states in neutron-rich $^{94,95,96}\mathrm{Kr}$

Author

Gerst, R.-B., Blazhev, A., Moschner, K., Doornenbal, P., Obertelli, A., Nomura, K., Ebran, J.-P., Hilaire, S., Libert, J., Authelet, G., Baba, H., Calvet, D., Château, F., Chen, S., Corsi, A., Delbart, A., Gheller, J.-M., Giganon, A., Gillibert, A., Lapoux, V., Motobayashi, T., Niikura, M., Paul, N., Roussé, J.-Y., Sakurai, H., Santamaria, C., Steppenbeck, D., Taniuchi, R., Uesaka, T., Ando, T., Arici, T., Browne, F., Bruce, A. M., Caroll, R., Chung, L. X., Cortés, M. L., Dewald, M., Ding, B., Flavigny, F., Franchoo, S., Górska, M., Gottardo, A., Jolie, J., Jungclaus, A., Lee, J., Lettmann, M., Linh, B. D., Liu, J., Liu, Z., Lizarazo, C., Momiyama, S., Nagamine, S., Nakatsuka, N., Nita, C. R., Nobs, C., Olivier, L., Orlandi, R., Patel, Z., Podolyák, Zs., Rudigier, M., Saito, T., Shand, C., Söderström, P.-A., Stefan, I., Vaquero, V., Werner, V., Wimmer, K., and Xu, Z.

Published
2022

47. γ-ray spectroscopy of low-lying yrast and non-yrast states in neutron- rich 94,95,96Kr

Author

Gerst, R-B, Blazhev, A., Moschner, K., Doornenbal, P., Obertelli, A., Nomura, K., Ebran, J-P, Hilaire, S., Libert, J., Authelet, G., Baba, H., Calvet, D., Chateau, F., Chen, S., Corsi, A., Delbart, A., Gheller, J-M, Giganon, A., Gillibert, A., Lapoux, V, Motobayashi, T., Niikura, M., Paul, N., Rousse, J-Y, Sakurai, H., Santamaria, C., Steppenbeck, D., Taniuchi, R., Uesaka, T., Ando, T., Arici, T., Browne, F., Bruce, A. M., Caroll, R., Chung, L. X., Cortes, M. L., Dewald, M., Ding, B., Flavigny, F., Franchoo, S., Gorska, M., Gottardo, A., Jolie, J., Jungclaus, A., Lee, J., Lettmann, M., Linh, B. D., Liu, J., Liu, Z., Lizarazo, C., Momiyama, S., Nagamine, S., Nakatsuka, N., Nita, C. R., Nobs, C., Olivier, L., Orlandi, R., Patel, Z., Podolyak, Zs, Rudigier, M., Saito, T., Shand, C., Soderstrom, P-A, Stefan, I, Vaquero, V., Werner, V, Wimmer, K., and Xu, Z.

Subjects
γ-ray spectroscopy, low-lying yrast state, non-yrast state
Abstract

We report on γ -ray spectroscopy of low-lying excited states in the neutron-rich 94, 95, 96Kr isotopes measured as part of the “Shell Evolution And Search for Two-plus energies At RIBF” (SEASTAR) campaign at the RIKEN Radioactive Isotope Beam Factory. Excited yrast and non-yrast states were observed, and half-lives extracted via GEANT4 simulations. In 94, 96Kr candidates for the 3− 1 state were identified. For 95Kr, the prompt SEASTAR data were combined with delayed spectroscopic data measured with the EURICA array to observe transitions on top of the known (7/2)+ isomer at a level energy of 195.5(3) keV. The comparison of the new experimental results with five-dimensional collective Hamiltonian (5DCH) and mapped interacting boson model (IBM) calculations, both using the Gogny D1M interaction, could suggest oblate-prolate shape coexistence already in 96Kr.

Published
2022

48. γ -ray spectroscopy of low-lying yrast and non-yrast states in neutron-rich Kr 94,95,96

Author

Gerst, R. B., Blazhev, A., Moschner, K., Doornenbal, P., Obertelli, A., Nomura, K., Ebran, J. P., Hilaire, S., Libert, J., Authelet, G., Baba, H., Calvet, D., Château, F., Chen, S., Corsi, A., Delbart, A., Gheller, J. M., Giganon, A., Gillibert, A., Lapoux, V., Motobayashi, T., Niikura, M., Paul, N., Roussé, J. Y., Sakurai, H., Santamaria, C., Steppenbeck, D., Taniuchi, R., Uesaka, T., Ando, T., Arici, T., Browne, F., Bruce, A. M., Caroll, R., Chung, L. X., Cortés, M. L., Dewald, M., Ding, B., Flavigny, F., Franchoo, S., Górska, M., Gottardo, A., Jolie, J., Jungclaus, Andrea, Lee, J., Lettmann, M., Linh, B.D., Liu, J., Liu, Z., Lizarazo, C., Momiyama, S., Nagamine, S., Nakatsuka, N., Nita, C.R., Nobs, C., Olivier, L., Orlandi, R., Patel, Z., Podolyák, Zs, Rudigier, M., Saito, T., Shand, C., Söderström, P. A., Stefan, I., Vaquero, Victor, Werner, V., Wimmer, K., Xu, Z., German Research Foundation, Federal Ministry of Education and Research (Germany), RIKEN Nishina Center for Accelerator-Based Science, Science and Technology Facilities Council (UK), Croatian Science Foundation, École Polytechnique Fédérale de Lausanne, National Natural Science Foundation of China, and Japan Society for the Promotion of Science

Abstract

11 pags., 16 figs., 1 tab., We report on γ-ray spectroscopy of low-lying excited states in the neutron-rich Kr94,95,96 isotopes measured as part of the "Shell Evolution And Search for Two-plus energies At RIBF"(SEASTAR) campaign at the RIKEN Radioactive Isotope Beam Factory. Excited yrast and non-yrast states were observed, and half-lives extracted via geant4 simulations. In Kr94,96 candidates for the 31- state were identified. For Kr95, the prompt SEASTAR data were combined with delayed spectroscopic data measured with the EURICA array to observe transitions on top of the known (7/2)+ isomer at a level energy of 195.5(3) keV. The comparison of the new experimental results with five-dimensional collective Hamiltonian (5DCH) and mapped interacting boson model (IBM) calculations, both using the Gogny D1M interaction, could suggest oblate-prolate shape coexistence already in Kr96., This work is supported by the Deutsche Forschungsgemeinschaft (DFG—German Research Foundation) under Grant No. BL 1513/1-1 and by the BMBF under Grants No. 05P15PKFNA, No. 05P19PKFNA, No. 05P15RDFN1, No. 05P19RDFN1, and No. 05P21RDFN1. We thank the RIKEN Nishina Centre accelerator staff and the BigRIPS team for providing the stable and high-intensity uranium beam and secondary beams, and the STFC (UK). The work of K. Nomura was supported by the Tenure Track Pilot Programme of the Croatian Science Foundation, the École Polytechnique Fédérale de Lausanne, and Project No. TTP-2018-07-3554, Exotic Nuclear Structure and Dynamics, with funds of the Croatian-Swiss Research Programme. B.D. and Z.L. were supported by the National Natural Science Foundation of China (Grants No. 12135004, No. 11635003, and No. 11961141004). R.T. was supported by JSPS Grant-in-Aid for JSPS Research Fellows JP14J08718.

Published
2022

49. Structure of the [formula omitted] As, Ge, Ga nuclei

Author

Sahin, E., de Angelis, G., Duchene, G., Faul, T., Gadea, A., Lisetskiy, A.F., Ackermann, D., Algora, A., Aydin, S., Azaiez, F., Bazzacco, D., Benzoni, G., Bostan, M., Byrski, T., Celikovic, I., Chapman, R., Corradi, L., Courtin, S., Curien, D., Pramanik, U. Datta, Didierjean, F., Dorvaux, O., Erduran, M.N., Erturk, S., Farnea, E., Fioretto, E., de France, G., Franchoo, S., Gall, B., Gottardo, A., Guiot, B., Haas, F., Ibrahim, F., Ince, E., Khouaja, A., Kusoglu, A., La Rana, G., Labiche, M., Lebhertz, D., Lenzi, S., Leoni, S., Lunardi, S., Mason, P., Mengoni, D., Michelagnoli, C., Modamio, V., Montagnoli, G., Montanari, D., Moro, R., Mouginot, B., Napoli, D.R., OʼDonnell, D., Oliveira, J.R.B., Ollier, J., Orlandi, R., Pollarolo, G., Recchia, F., Robin, J., Salsac, M.-D., Scarlassara, F., Singh, R.P., Silvestri, R., Smith, J.F., Stefan, I., Stefanini, A.M., Subotic, K., Szilner, S., Tonev, D., Torres, D.A., Trotta, M., Ujic, P., Ur, C., Valiente-Dobón, J.J., Verney, D., Yalcinkaya, M., Wady, P.T., Wiedemann, K.T., and Zuber, K.

Published
2012
Full Text
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50. The EUFOREA pocket guide for chronic rhinosinusitis.

Author

Hellings, P. W., Fokkens, W. J., Orlandi, R., Adriaensen, G. F., Alobid, I., Baroody, F. M., Bjermer, L., Senior, B. A., Cervin, A., Cohen, N. A., Constantinidis, J., De Corso, E., Desrosiers, M., Diamant, Z., Douglas, R. G., Gane, S., Gevaert, P., Han, J. K., Harvey, R. J., and Hopkins, C.

Published
2023
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