532 results on '"Orkin, S H"'
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2. Cell Cycle-Dependent Initiation and Lineage-Dependent Abrogation of GATA-1 Expression in Pure Differentiating Hematopoietic Progenitors
3. Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas
4. MicroRNA-21 Deficiency Leads to an Attenuated Asthma Response in Mice: 850
5. Epigenetic memory in induced pluripotent stem cells
6. The transcriptional network controlling pluripotency in ES cells: IL6A-1
7. TRANSCRIPTION FACTORS IN LINEAGE COMMITMENT AND CELL DIFFERENTIATION
8. The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability
9. Xp21 DNA microdeletion in a patient with chronic granulomatous disease, retinitis pigmentosa, and McLeod phenotype
10. Restriction site polymorphism in the phosphoglycerate kinase gene on the X chromosome
11. Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy
12. Delineating the mixed lineage leukemia gene expression network in hematopoietic stem cells
13. The Switch from Fetal to Adult Hemoglobin
14. Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas
15. Isolation of mouse X-chromosome specific DNA from an X-enriched lambda phage library derived from flow sorted chromosomes
16. Fetal expression of a human Aγ globin transgene rescues globin chain imbalance but not hemolysis in EKLF null mouse embryos
17. Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG
18. Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
19. Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line
20. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.
21. Silencing of human fetal globin expression is impaired in the absence of the adult beta-globin gene activator protein EKLF.
22. Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.
23. Complexity of the erythroid transcription factor NF-E2 as revealed by gene targeting of the mouse p18 NF-E2 locus.
24. Estrogen-induced apoptosis by inhibition of the erythroid transcription factor GATA-1
25. In vitro differentiation of murine embryonic stem cells. New approaches to old problems.
26. Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis.
27. Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2.
28. Ligand-dependent repression of the erythroid transcription factor GATA-1 by the estrogen receptor
29. Self-association of the erythroid transcription factor GATA-1 mediated by its zinc finger domains
30. Normal and Expanded Huntington’s Disease Gene Alleles Produce Distinguishable Proteins Due to Translation Across the CAG Repeat
31. Expression of c-MYC under the control of GATA-1 regulatory sequences causes erythroleukemia in transgenic mice.
32. Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF
33. Rescue of GATA-1-deficient embryonic stem cells by heterologous GATA-binding proteins
34. The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line
35. Hematopoietic development of vav-/- mouse embryonic stem cells.
36. Sequence-specific DNA binding of individual cut repeats of the human CCAAT displacement/cut homeodomain protein.
37. Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.
38. The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene.
39. Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox.
40. Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner
41. Loss of erythropoietin responsiveness in erythroid progenitors due to expression of the Evi-1 myeloid-transforming gene.
42. DNA-binding specificity of GATA family transcription factors
43. Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart.
44. In vivo protein-DNA interactions at hypersensitive site 3 of the human beta-globin locus control region.
45. In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction
46. Chronic Granulomatous Disease
47. Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells.
48. Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease.
49. Expression of GATA-binding proteins during embryonic development in Xenopus laevis.
50. Activation of the erythropoietin receptor promoter by transcription factor GATA-1.
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